NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|16804422|ref|NP_465907|]
View 

monovalent cation/H+ antiporter subunit G [Listeria monocytogenes EGD-e]

Protein Classification

cation:proton antiporter( domain architecture ID 10014012)

cation:proton antiporter functions in maintaining cation homeostasis and the pH of actively metabolizing cells; it may also be involved in regulating cell volume

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK12585 PRK12585
putative monovalent cation/H+ antiporter subunit G; Reviewed
 1-197 1.77e-114

putative monovalent cation/H+ antiporter subunit G; Reviewed


:

Pssm-ID: 183610  Cd Length: 197  Bit Score: 323.94  E-value: 1.77e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422    1 MNVIIEIIISIMIIIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT 80
Cdd:PRK12585   1 MNVIIEIIISIMILIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   81 TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKDDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ 160
Cdd:PRK12585  81 TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKDDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ 160

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 16804422  161 EREREEQTIEEQSDDSEHEIIEQDESETESDDDKSEK 197
Cdd:PRK12585 161 EREREEQTIEEQSDDSEHEIIEQDESETESDDDKTEK 197
 
Name Accession Description Interval E-value
PRK12585 PRK12585
putative monovalent cation/H+ antiporter subunit G; Reviewed
 1-197 1.77e-114

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 183610  Cd Length: 197  Bit Score: 323.94  E-value: 1.77e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422    1 MNVIIEIIISIMIIIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT 80
Cdd:PRK12585   1 MNVIIEIIISIMILIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   81 TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKDDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ 160
Cdd:PRK12585  81 TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKDDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ 160

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 16804422  161 EREREEQTIEEQSDDSEHEIIEQDESETESDDDKSEK 197
Cdd:PRK12585 161 EREREEQTIEEQSDDSEHEIIEQDESETESDDDKTEK 197
MnhG COG1320
Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];
16-110 1.95e-28

Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440931  Cd Length: 110  Bit Score: 102.64  E-value: 1.95e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422  16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSgeGFNARVLLAVLFIFLTTPVASHLINRAAYDT 95
Cdd:COG1320  13 GALFALVGAIGLLRLPDFYTRLHAATKATTLGLGLILLGVALYFGSG--AVSLKLLLIILFLLLTAPVAAHLLARAAYRS 90

                        90
                ....*....|....*.
gi 16804422  96 GVPLAIR-IRDQLRSV 110
Cdd:COG1320  91 GVPPWEKtVVDELAED 106
PhaG_MnhG_YufB pfam03334
Na+/H+ antiporter subunit; This family includes PhaG from Rhizobium meliloti, MnhG from ...
 16-93 9.12e-27

Na+/H+ antiporter subunit; This family includes PhaG from Rhizobium meliloti, MnhG from Staphylococcus aureus, YufB from Bacillus subtilis.


Pssm-ID: 460887  Cd Length: 82  Bit Score: 97.13  E-value: 9.12e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16804422    16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLTTPVASHLINRAAY 93
Cdd:pfam03334   5 GAFFALVGAIGLLRLPDVYTRLHAATKADTLGLGLILLGLALYFGLGGGGVALKLLLIILFLLLTAPVAAHLIARAAY 82
CPA3_mnhG_phaG TIGR01300
monovalent cation/proton antiporter, MnhG/PhaG subunit; This model represents a subfamily of ...
 16-107 1.47e-22

monovalent cation/proton antiporter, MnhG/PhaG subunit; This model represents a subfamily of small, transmembrane proteins believed to be components of Na+/H+ and K+/H+ antiporters. Members, including proteins designated MnhG from Staphylococcus aureus and PhaG from Rhizobium meliloti, show some similarity to chain L of the NADH dehydrogenase I, which also translocates protons. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130367  Cd Length: 97  Bit Score: 86.99  E-value: 1.47e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422    16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLTTPVASHLINRAAYDT 95
Cdd:TIGR01300   6 GAFFTLLGAIGLVRFPDVYTRLHAATKGTTLGTILILLGVALIALVLDLAVSIKLLLIALFILLTNPVGAHLLARAAYLS 85

                          90
                  ....*....|..
gi 16804422    96 GVPLAIRIRDQL 107
Cdd:TIGR01300  86 GVKPSRSVVDAL 97
 
Name Accession Description Interval E-value
PRK12585 PRK12585
putative monovalent cation/H+ antiporter subunit G; Reviewed
 1-197 1.77e-114

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 183610  Cd Length: 197  Bit Score: 323.94  E-value: 1.77e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422    1 MNVIIEIIISIMIIIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT 80
Cdd:PRK12585   1 MNVIIEIIISIMILIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   81 TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKDDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ 160
Cdd:PRK12585  81 TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKDDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ 160

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 16804422  161 EREREEQTIEEQSDDSEHEIIEQDESETESDDDKSEK 197
Cdd:PRK12585 161 EREREEQTIEEQSDDSEHEIIEQDESETESDDDKTEK 197
MnhG COG1320
Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];
16-110 1.95e-28

Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440931  Cd Length: 110  Bit Score: 102.64  E-value: 1.95e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422  16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSgeGFNARVLLAVLFIFLTTPVASHLINRAAYDT 95
Cdd:COG1320  13 GALFALVGAIGLLRLPDFYTRLHAATKATTLGLGLILLGVALYFGSG--AVSLKLLLIILFLLLTAPVAAHLLARAAYRS 90

                        90
                ....*....|....*.
gi 16804422  96 GVPLAIR-IRDQLRSV 110
Cdd:COG1320  91 GVPPWEKtVVDELAED 106
PhaG_MnhG_YufB pfam03334
Na+/H+ antiporter subunit; This family includes PhaG from Rhizobium meliloti, MnhG from ...
 16-93 9.12e-27

Na+/H+ antiporter subunit; This family includes PhaG from Rhizobium meliloti, MnhG from Staphylococcus aureus, YufB from Bacillus subtilis.


Pssm-ID: 460887  Cd Length: 82  Bit Score: 97.13  E-value: 9.12e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16804422    16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLTTPVASHLINRAAY 93
Cdd:pfam03334   5 GAFFALVGAIGLLRLPDVYTRLHAATKADTLGLGLILLGLALYFGLGGGGVALKLLLIILFLLLTAPVAAHLIARAAY 82
PRK12674 PRK12674
putative monovalent cation/H+ antiporter subunit G; Reviewed
 16-99 4.92e-25

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 237169  Cd Length: 99  Bit Score: 93.35  E-value: 4.92e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFfhSGEGFNARVLLAVLFIFLTTPVASHLINRAAYDT 95
Cdd:PRK12674  14 GAFFALVGAIGLVRLPDVYTRLHAATKATTLGLGLVLLASALYF--AGGGNSLKALLIILFLFLTAPVAAHLLARAAYRT 91


                 ....
gi 16804422   96 GVPL 99
Cdd:PRK12674  92 GVPL 95
PRK12586 PRK12586
Na+/H+ antiporter subunit G;
16-100 1.19e-23

Na+/H+ antiporter subunit G;


Pssm-ID: 237147  Cd Length: 145  Bit Score: 91.38  E-value: 1.19e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLTTPVASHLINRAAYDT 95
Cdd:PRK12586  19 GSIIALISAIGIVKFQDVFLRSHAATKSSTLSVLLTLIGVLIYFIVNTGFFSVRLLLSLVFINLTSPVGMHLIARAAYRN 98


                 ....*
gi 16804422   96 GVPLA 100
Cdd:PRK12586  99 GAYMY 103
CPA3_mnhG_phaG TIGR01300
monovalent cation/proton antiporter, MnhG/PhaG subunit; This model represents a subfamily of ...
 16-107 1.47e-22

monovalent cation/proton antiporter, MnhG/PhaG subunit; This model represents a subfamily of small, transmembrane proteins believed to be components of Na+/H+ and K+/H+ antiporters. Members, including proteins designated MnhG from Staphylococcus aureus and PhaG from Rhizobium meliloti, show some similarity to chain L of the NADH dehydrogenase I, which also translocates protons. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130367  Cd Length: 97  Bit Score: 86.99  E-value: 1.47e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422    16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLTTPVASHLINRAAYDT 95
Cdd:TIGR01300   6 GAFFTLLGAIGLVRFPDVYTRLHAATKGTTLGTILILLGVALIALVLDLAVSIKLLLIALFILLTNPVGAHLLARAAYLS 85

                          90
                  ....*....|..
gi 16804422    96 GVPLAIRIRDQL 107
Cdd:TIGR01300  86 GVKPSRSVVDAL 97
PRK12587 PRK12587
putative monovalent cation/H+ antiporter subunit G; Reviewed
 16-98 6.51e-22

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 183612  Cd Length: 118  Bit Score: 85.99  E-value: 6.51e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLTTPVASHLINRAAYDT 95
Cdd:PRK12587  17 GALISALAAIGLLRLEDVYSRAHAAGKASTLGAMSLLFGTFLYFIATQGYVNMQLIVGIIFVLITGPLSSHMIMKAAYNI 96


                 ...
gi 16804422   96 GVP 98
Cdd:PRK12587  97 KTP 99
PRK12672 PRK12672
putative monovalent cation/H+ antiporter subunit G; Reviewed
 21-97 1.18e-12

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 183671  Cd Length: 118  Bit Score: 61.65  E-value: 1.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   21 ILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGY-FFHSGEGFNARVL-------LAVLFIFLTTPVASHLINRAA 92
Cdd:PRK12672  19 LLGSIALHRFPDVYTRLHGATKCTTFGTIFAVLAVVTHaLYRLRLTGDPKYLqmalhsfVALIALLLTNPVGAHAIARAA 98


                 ....*
gi 16804422   93 YDTGV 97
Cdd:PRK12672  99 HLSGY 103
PRK12671 PRK12671
putative monovalent cation/H+ antiporter subunit G; Reviewed
 16-92 1.47e-12

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 183670  Cd Length: 120  Bit Score: 61.58  E-value: 1.47e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16804422   16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLTTPVASHLINRAA 92
Cdd:PRK12671  22 GAGLTLIGTIGLVRLKSFYERLHAPTLGTSWGAGGILIASILYFSVLQSRPVLHEVLIGVFVVVTTPVTLMLLSRAA 98
PRK12670 PRK12670
putative monovalent cation/H+ antiporter subunit G; Reviewed
 16-93 1.27e-11

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 183669  Cd Length: 99  Bit Score: 58.58  E-value: 1.27e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16804422   16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLfatVGYFFHSGEG-FNARVLLAVLFIFLTTPVASHLINRAAY 93
Cdd:PRK12670  13 GIFLIVISVIGVIRFPDFYTRLHAAGITDSLGAALIL---IGLAMQCGFSvFTVKVLLLICLLWITSTTASYALARSAY 88
PRK12675 PRK12675
putative monovalent cation/H+ antiporter subunit G; Reviewed
 16-97 4.61e-11

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 171652  Cd Length: 104  Bit Score: 57.10  E-value: 4.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVgyfFHSGEGFNARVLLAVL--FIFLTTPVASHLINRAAY 93
Cdd:PRK12675  10 GYSIMFFGALGLLRFPDVYTRLHAATKCDTGGAMGIILALA---LASDASLLIKLKFLVLafLIAMINPMVSHAIARGAY 86


                 ....
gi 16804422   94 DTGV 97
Cdd:PRK12675  87 KMGI 90
PRK12592 PRK12592
putative monovalent cation/H+ antiporter subunit G; Reviewed
 16-97 1.01e-03

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 183613  Cd Length: 126  Bit Score: 37.53  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16804422   16 GGLLSILAAIGVIRLPDVYTRTHAAGISNTFGvslLLFATVG---------YFFHSGEGFNARVLLAVLFIFLTTPVASH 86
Cdd:PRK12592  18 GAFLSFSASIGLIRFRDTMSRVHAITKPQTTG---LILTVVGaiirvlgheDFDQSQRGDLGVLVLLVLFALLTSPVTAQ 94

                         90
                 ....*....|.
gi 16804422   87 LINRAAYDTGV 97
Cdd:PRK12592  95 RVGRVSRREGL 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH