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Conserved domains on  [gi|16766746|ref|NP_462361|]
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CPA2 family K+:H+ antiporter [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

Protein Classification

glutathione-regulated potassium-efflux system protein KefB( domain architecture ID 11480016)

glutathione-regulated potassium-efflux system protein KefB is a pore-forming subunit of a potassium efflux system that facilitates K(+)/H(+) antiport and confers protection against electrophiles

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK03659 PRK03659
glutathione-regulated potassium-efflux system protein KefB; Provisional
 1-600 0e+00

glutathione-regulated potassium-efflux system protein KefB; Provisional


:

Pssm-ID: 179625 [Multi-domain]  Cd Length: 601  Bit Score: 1163.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    1 MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRL 80
Cdd:PRK03659   1 MEGSDLLTAGVLFLFAAVVAVPLAQRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   81 WQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV 160
Cdd:PRK03659  81 WQLRRSIFGVGAAQVLLSAAVLAGLLMLTDFSWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  161 IPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMA 240
Cdd:PRK03659 161 IPALALVPLLAGSADEHFDWMKIGMKVLAFAGMLIGGRYLLRPLFRFIAASGVREVFTAAALLLVLGSALFMDALGLSMA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  241 LGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRS 320
Cdd:PRK03659 241 LGTFIAGVLLAESEYRHELEIAIEPFKGLLLGLFFISVGMALNLGVLYTHLLWVLISVVVLVAVKGLVLYLLARLYGLRS 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  321 SERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEKPWVEDDK 400
Cdd:PRK03659 321 SERMQFAGVLSQGGEFAFVLFSAASSQRLLQGDQMALLLVVVTLSMMTTPLLMKLIDKWLARRLNGPEEEDEKPWVEDDK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  401 PQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMK 480
Cdd:PRK03659 401 PQVIIVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQLELLRAAGAEKAEAIVITCNEPEDTMK 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  481 LVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELI 560
Cdd:PRK03659 481 IVELCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQQHFRRLDMRMLRELM 560

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|.
gi 16766746  561 PEHS-DMVQISRAREARRELEEIFQREMQQERRQLDGWDEF 600
Cdd:PRK03659 561 PQHNgDVVQISRAKEARRELEEIFQREMQQERRQLDGWDEF 601
 
Name Accession Description Interval E-value
PRK03659 PRK03659
glutathione-regulated potassium-efflux system protein KefB; Provisional
 1-600 0e+00

glutathione-regulated potassium-efflux system protein KefB; Provisional


Pssm-ID: 179625 [Multi-domain]  Cd Length: 601  Bit Score: 1163.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    1 MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRL 80
Cdd:PRK03659   1 MEGSDLLTAGVLFLFAAVVAVPLAQRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   81 WQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV 160
Cdd:PRK03659  81 WQLRRSIFGVGAAQVLLSAAVLAGLLMLTDFSWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  161 IPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMA 240
Cdd:PRK03659 161 IPALALVPLLAGSADEHFDWMKIGMKVLAFAGMLIGGRYLLRPLFRFIAASGVREVFTAAALLLVLGSALFMDALGLSMA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  241 LGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRS 320
Cdd:PRK03659 241 LGTFIAGVLLAESEYRHELEIAIEPFKGLLLGLFFISVGMALNLGVLYTHLLWVLISVVVLVAVKGLVLYLLARLYGLRS 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  321 SERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEKPWVEDDK 400
Cdd:PRK03659 321 SERMQFAGVLSQGGEFAFVLFSAASSQRLLQGDQMALLLVVVTLSMMTTPLLMKLIDKWLARRLNGPEEEDEKPWVEDDK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  401 PQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMK 480
Cdd:PRK03659 401 PQVIIVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQLELLRAAGAEKAEAIVITCNEPEDTMK 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  481 LVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELI 560
Cdd:PRK03659 481 IVELCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQQHFRRLDMRMLRELM 560

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|.
gi 16766746  561 PEHS-DMVQISRAREARRELEEIFQREMQQERRQLDGWDEF 600
Cdd:PRK03659 561 PQHNgDVVQISRAKEARRELEEIFQREMQQERRQLDGWDEF 601
KefB COG0475
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
 4-383 1.18e-114

Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];


Pssm-ID: 440243 [Multi-domain]  Cd Length: 384  Bit Score: 346.75  E-value: 1.18e-114
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   4 ADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQL 83
Cdd:COG0475   3 ASLLLQLGLLLLAAVLAGLLARRLGLPSVLGYILAGILLGPSGLGLIEDSEALELLAELGVVLLLFLIGLELDLKRLRKM 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  84 RRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPA 163
Cdd:COG0475  83 GRRALGIGLLQVLLPFLLGFLLALLLGLSLAAALFLGAALAATSTAIVLKVLKELGLLKTPLGQLILGVALFDDIAAILL 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 164 LALVPLLAGSADEHFDWFKVAMKVLAF-AVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALG 242
Cdd:COG0475 163 LALVPALAGGGSVAGSLLLALLKALLFlALLLLVGRYLLRRLFRLVARTRSRELFLLFALLLVLLAAALAELLGLSAALG 242

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 243 TFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSE 322
Cdd:COG0475 243 AFLAGLVLAESEYRHELEEKIEPFGDLFLPLFFVSVGLSLDLSALLSNPLLALLLVLAAIVGKLLGAYLAARLFGLSRRE 322

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16766746 323 RMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRR 383
Cdd:COG0475 323 ALRIGLLLAPRGEFALVLASLGLSAGLISPELFAALVLVVLLTTLLTPLLLRLALRLAERA 383
2a37 TIGR00932
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
 26-283 2.65e-95

transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273348 [Multi-domain]  Cd Length: 273  Bit Score: 293.02  E-value: 2.65e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    26 RLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGL 105
Cdd:TIGR00932  13 RLGIPSVLGYLLAGVLIGPSGLGLISNVEGVNHLAEFGVILLMFLIGLELDLERLWKLRKAAFGVGVLQVLVPGVLLGLL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   106 L-MLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSA-DEHFDWFKV 183
Cdd:TIGR00932  93 LgHLLGLALGAAVVIGIILALSSTAVVVQVLKERGLLKTPFGQTVLGILLFQDIAVVPLLALLPLLATSAsTEHVALALL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   184 AMKVLAFAV-MLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENA 262
Cdd:TIGR00932 173 LLKVFLAFLlLVLLGRWLLRPVLRLTAELRPSELFTAGSLLLMFGSAYFADLLGLSMALGAFLAGVVLSESEYRHKLESD 252

                         250       260
                  ....*....|....*....|.
gi 16766746   263 IDPFKGLLLGLFFISVGMSLN 283
Cdd:TIGR00932 253 LEPIGGVLLPLFFISVGMSVD 273
Na_H_Exchanger pfam00999
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
 11-374 4.36e-57

Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.


Pssm-ID: 425982 [Multi-domain]  Cd Length: 377  Bit Score: 196.71  E-value: 4.36e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    11 VLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILH-FSELGVVFLMFIIGLELNPSRLWQLRRSIFG 89
Cdd:pfam00999   2 VLLILLALLAPLLARRLKLPPIVGLIIAGILLGPSGLGLISEVDEDLEvLSNLGLPPLLFLAGLELDLRELRKNGGSILL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    90 VGAAQVLLSAAVLAGLL--MLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALV 167
Cdd:pfam00999  82 LALLGVLIPFVLIGLLLylLGLGIPLLEALLFGAILSATSPVVVLAILKELGRVPERLGTLLLGESVLNDGVAVVLLAVL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   168 PLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIA--ASGVREVFTAATLLLVLSAALFMDALGLSMALGTFI 245
Cdd:pfam00999 162 LALAQGVGGGSDLGWLLLIFLVVAVGGLLLGLLIGWLLRLITrfTDDDRELEVLLVLLLALLAALLAEALGVSGILGAFL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   246 AGVLLAESEYRHELENAIDPF-KGLLLGLFFISVGMSLNLGVLYTHLLW-VAASVVILVVIKMLTLYLLARLYGIRSSER 323
Cdd:pfam00999 242 AGLVLSEYPFANKLSEKLEPFgYGLFNPLFFVLVGLSLDLSSLLLSVWIlVLLALVAILLGRFLGVFLLLRLLGLSLREA 321

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 16766746   324 MQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSM-----MTTPLLMK 374
Cdd:pfam00999 322 LIIGFGGLQRGAVSLALAAIGPLLGIIARELYPLLIVVVLFTVlvqgiTLKPLLFK 377
 
Name Accession Description Interval E-value
PRK03659 PRK03659
glutathione-regulated potassium-efflux system protein KefB; Provisional
 1-600 0e+00

glutathione-regulated potassium-efflux system protein KefB; Provisional


Pssm-ID: 179625 [Multi-domain]  Cd Length: 601  Bit Score: 1163.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    1 MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRL 80
Cdd:PRK03659   1 MEGSDLLTAGVLFLFAAVVAVPLAQRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   81 WQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV 160
Cdd:PRK03659  81 WQLRRSIFGVGAAQVLLSAAVLAGLLMLTDFSWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  161 IPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMA 240
Cdd:PRK03659 161 IPALALVPLLAGSADEHFDWMKIGMKVLAFAGMLIGGRYLLRPLFRFIAASGVREVFTAAALLLVLGSALFMDALGLSMA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  241 LGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRS 320
Cdd:PRK03659 241 LGTFIAGVLLAESEYRHELEIAIEPFKGLLLGLFFISVGMALNLGVLYTHLLWVLISVVVLVAVKGLVLYLLARLYGLRS 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  321 SERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEKPWVEDDK 400
Cdd:PRK03659 321 SERMQFAGVLSQGGEFAFVLFSAASSQRLLQGDQMALLLVVVTLSMMTTPLLMKLIDKWLARRLNGPEEEDEKPWVEDDK 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  401 PQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMK 480
Cdd:PRK03659 401 PQVIIVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQLELLRAAGAEKAEAIVITCNEPEDTMK 480

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  481 LVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELI 560
Cdd:PRK03659 481 IVELCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQQHFRRLDMRMLRELM 560

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|.
gi 16766746  561 PEHS-DMVQISRAREARRELEEIFQREMQQERRQLDGWDEF 600
Cdd:PRK03659 561 PQHNgDVVQISRAKEARRELEEIFQREMQQERRQLDGWDEF 601
PRK03562 PRK03562
glutathione-regulated potassium-efflux system protein KefC; Provisional
 1-597 0e+00

glutathione-regulated potassium-efflux system protein KefC; Provisional


Pssm-ID: 235131 [Multi-domain]  Cd Length: 621  Bit Score: 634.34  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    1 MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRL 80
Cdd:PRK03562   1 MMDSHTLIQALIYLGAAVLIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDVESILHFAEFGVVLMLFVIGLELDPQRL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   81 WQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV 160
Cdd:PRK03562  81 WKLRRSIFGGGALQMVACGGLLGLFCMLLGLRWQVALLIGLGLALSSTAIAMQAMNERNLMVTQMGRSAFAILLFQDIAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  161 IPALALVPLLAGSADEHFD---WFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGL 237
Cdd:PRK03562 161 IPLVAMIPLLAASGASTTLgafALSALKVAGALALVVLGGRYVTRPALRFVARSGLREVFTAVALFLVFGFGLLMEEVGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  238 SMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYG 317
Cdd:PRK03562 241 SMALGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIAVGMSIDFGTLLENPLRILILLLGFLAIKIAMLWLLARPLG 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  318 IRSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEkpwVE 397
Cdd:PRK03562 321 VPRKQRRWFAVLLGQGGEFAFVVFGAAQMANVLEPEWAKLLTLAVALSMAATPLLLVLLDRLEQSRTEEAREADE---ID 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  398 DDKPQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPED 477
Cdd:PRK03562 398 EQQPRVIIAGFGRFGQIVGRLLLSSGVKMTVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQT 477

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  478 TMKLVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLR 557
Cdd:PRK03562 478 SLQLVELVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKSGRLVLESLGLGPYEARERADRFRRHNLQMVE 557

                        570       580       590       600
                 ....*....|....*....|....*....|....*....|..
gi 16766746  558 ELIPEHSDMVQ-ISRAREARRELEEIFQRE-MQQERRQLDGW 597
Cdd:PRK03562 558 EMAPHENDTKKrAAVAKQTSAMLSEIITEDrEHLSLIQRHGW 599
KefB COG0475
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
 4-383 1.18e-114

Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];


Pssm-ID: 440243 [Multi-domain]  Cd Length: 384  Bit Score: 346.75  E-value: 1.18e-114
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   4 ADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQL 83
Cdd:COG0475   3 ASLLLQLGLLLLAAVLAGLLARRLGLPSVLGYILAGILLGPSGLGLIEDSEALELLAELGVVLLLFLIGLELDLKRLRKM 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  84 RRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPA 163
Cdd:COG0475  83 GRRALGIGLLQVLLPFLLGFLLALLLGLSLAAALFLGAALAATSTAIVLKVLKELGLLKTPLGQLILGVALFDDIAAILL 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 164 LALVPLLAGSADEHFDWFKVAMKVLAF-AVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALG 242
Cdd:COG0475 163 LALVPALAGGGSVAGSLLLALLKALLFlALLLLVGRYLLRRLFRLVARTRSRELFLLFALLLVLLAAALAELLGLSAALG 242

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 243 TFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSE 322
Cdd:COG0475 243 AFLAGLVLAESEYRHELEEKIEPFGDLFLPLFFVSVGLSLDLSALLSNPLLALLLVLAAIVGKLLGAYLAARLFGLSRRE 322

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16766746 323 RMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRR 383
Cdd:COG0475 323 ALRIGLLLAPRGEFALVLASLGLSAGLISPELFAALVLVVLLTTLLTPLLLRLALRLAERA 383
2a37 TIGR00932
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
 26-283 2.65e-95

transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273348 [Multi-domain]  Cd Length: 273  Bit Score: 293.02  E-value: 2.65e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    26 RLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGL 105
Cdd:TIGR00932  13 RLGIPSVLGYLLAGVLIGPSGLGLISNVEGVNHLAEFGVILLMFLIGLELDLERLWKLRKAAFGVGVLQVLVPGVLLGLL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   106 L-MLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSA-DEHFDWFKV 183
Cdd:TIGR00932  93 LgHLLGLALGAAVVIGIILALSSTAVVVQVLKERGLLKTPFGQTVLGILLFQDIAVVPLLALLPLLATSAsTEHVALALL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   184 AMKVLAFAV-MLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENA 262
Cdd:TIGR00932 173 LLKVFLAFLlLVLLGRWLLRPVLRLTAELRPSELFTAGSLLLMFGSAYFADLLGLSMALGAFLAGVVLSESEYRHKLESD 252

                         250       260
                  ....*....|....*....|.
gi 16766746   263 IDPFKGLLLGLFFISVGMSLN 283
Cdd:TIGR00932 253 LEPIGGVLLPLFFISVGMSVD 273
RosB COG4651
Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and ...
 1-557 1.54e-93

Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and metabolism];


Pssm-ID: 443689 [Multi-domain]  Cd Length: 564  Bit Score: 298.43  E-value: 1.54e-93
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   1 MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRL 80
Cdd:COG4651   1 MHETPLITTIALILGLAAVLGLLAQRLRQPPIVGYLLAGVLIGPFTPGLVADVELIEQLAEIGVILLLFGVGLEFSLKDL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  81 WQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV 160
Cdd:COG4651  81 LAVRKIALPGALLQIALTTLLGFGIALLLGWSLGESLVFGLALSLSSTVVLLKLLEDRGELDTLHGRIAVGWLIVQDLAV 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 161 IPALALVPLLAGSADEHF-DWFKVAMKVLAF-AVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLS 238
Cdd:COG4651 161 VLMLVLLPALAGGGGGLLgTLGLTLLKVALFvALMLVVGRRVIPWLLHRVARTRSRELFLLAVLAICLGVAYLAALFGLS 240

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 239 MALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGI 318
Cdd:COG4651 241 FALGAFLAGMVLAESEYSHQAAAELLPLRDAFAVLFFVSVGMLFDPSFLLENPLPVLALLLIVLIGKPLIAFLIVLALGY 320

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 319 RSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEEND----EKP 394
Cdd:COG4651 321 PLRTALLVGLSLAQIGEFSFILAALGLSLGLLSEEAYQLILAVAILTIALSPYLIALADPLYARLERRPPLAArlerDRP 400

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 395 WVEDDKPQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNE 474
Cdd:COG4651 401 EESDLVVHVVVVGGGGGGGGLALRLLLRGIVVVVVVDNVEEVVRARRRGGIAGGGGAAADLELLAALLAAAAIAVVAIPA 480

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 475 PEDTMKLVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMR 554
Cdd:COG4651 481 AAAALLLIAAARRALPLLIIIARAARRAEEEELLLAGAVEVVVEEEEEAAEAALLLLLLLLLLRALAERAILRAARRRLR 560


                ...
gi 16766746 555 MLR 557
Cdd:COG4651 561 AER 563
Kch COG1226
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];
279-555 1.52e-64

Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];


Pssm-ID: 440839 [Multi-domain]  Cd Length: 279  Bit Score: 213.05  E-value: 1.52e-64
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 279 GMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALL 358
Cdd:COG1226   1 LGLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLAALALAALLLLLLLAGGGGFFLLLLLAAAALLLLLLLAAALL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 359 LVTVTLSMMTTPLLMKGIDKW--LSRRLNGPEENDEKPWVEDDKPQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAV 436
Cdd:COG1226  81 LLLVLLLLLLLLLLLLLLALLllLLALAAREEEAEAAEDAIDLEGHVIIAGFGRVGQIVARLLRAEGIPFVVIDLDPERV 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 437 NLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFPHLHILARARGRVEAHELLQAGVTQFS 516
Cdd:COG1226 161 EELRRFGIKVYYGDATRPDVLEAAGIERARALVVAIDDPEAALRIVELARELNPDLKIIARARDREHAEELRQAGADEVV 240

                       250       260       270
                ....*....|....*....|....*....|....*....
gi 16766746 517 RETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRM 555
Cdd:COG1226 241 RETFESALQLARHALEALGVPEEEAARAIQEFRRRDYER 279
Na_H_Exchanger pfam00999
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
 11-374 4.36e-57

Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.


Pssm-ID: 425982 [Multi-domain]  Cd Length: 377  Bit Score: 196.71  E-value: 4.36e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    11 VLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILH-FSELGVVFLMFIIGLELNPSRLWQLRRSIFG 89
Cdd:pfam00999   2 VLLILLALLAPLLARRLKLPPIVGLIIAGILLGPSGLGLISEVDEDLEvLSNLGLPPLLFLAGLELDLRELRKNGGSILL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746    90 VGAAQVLLSAAVLAGLL--MLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALV 167
Cdd:pfam00999  82 LALLGVLIPFVLIGLLLylLGLGIPLLEALLFGAILSATSPVVVLAILKELGRVPERLGTLLLGESVLNDGVAVVLLAVL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   168 PLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIA--ASGVREVFTAATLLLVLSAALFMDALGLSMALGTFI 245
Cdd:pfam00999 162 LALAQGVGGGSDLGWLLLIFLVVAVGGLLLGLLIGWLLRLITrfTDDDRELEVLLVLLLALLAALLAEALGVSGILGAFL 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   246 AGVLLAESEYRHELENAIDPF-KGLLLGLFFISVGMSLNLGVLYTHLLW-VAASVVILVVIKMLTLYLLARLYGIRSSER 323
Cdd:pfam00999 242 AGLVLSEYPFANKLSEKLEPFgYGLFNPLFFVLVGLSLDLSSLLLSVWIlVLLALVAILLGRFLGVFLLLRLLGLSLREA 321

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 16766746   324 MQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSM-----MTTPLLMK 374
Cdd:pfam00999 322 LIIGFGGLQRGAVSLALAAIGPLLGIIARELYPLLIVVVLFTVlvqgiTLKPLLFK 377
PRK10669 PRK10669
putative cation:proton antiport protein; Provisional
 26-526 1.04e-53

putative cation:proton antiport protein; Provisional


Pssm-ID: 182633 [Multi-domain]  Cd Length: 558  Bit Score: 192.24  E-value: 1.04e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   26 RLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGL 105
Cdd:PRK10669  27 RLRISPLVGYLLAGVLAGPFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKSIAIPGAIAQIAVATLLGMAL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  106 LMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEH-------- 177
Cdd:PRK10669 107 SAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLVMVLTLVLLPAVAGMMEQGdvgfatla 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  178 FDWFKVAMKVLAF-AVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAAL----FMDAlglSMALGTFIAGVLLAE 252
Cdd:PRK10669 187 VDLGITIGKVIAFiAIMMLVGRRLVPWILARSAATGSRELFTLSVLALALGIAFgaveLFDV---SFALGAFFAGMVLNE 263

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  253 SEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQ 332
Cdd:PRK10669 264 SELSHRAAHDTLPLRDAFAVLFFVSVGMLFDPMILIQQPLAVLATLAIIVFGKSLAAFFLVRLFGHSRRTALTIAASLAQ 343

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  333 GGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRlNGPEENDEKPWVEDDKP-------QVIV 405
Cdd:PRK10669 344 IGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFTLLERYLAKT-ETLEEQTLEEAIEEEKQipvdicnHALL 422

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  406 VGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVALC 485
Cdd:PRK10669 423 VGYGRVGSLLGEKLLAAGIPLVVIETSRTRVDELRERGIRAVLGNAANEEIMQLAHLDCARWLLLTIPNGYEAGEIVASA 502

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....
gi 16766746  486 QQHFPHLHILARARGRVEAHELLQAGVTQF---SRETFSSALEL 526
Cdd:PRK10669 503 REKRPDIEIIARAHYDDEVAYITERGANQVvmgEREIARTMLEL 546
TrkA_N pfam02254
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ...
 403-514 1.23e-25

TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.


Pssm-ID: 426679 [Multi-domain]  Cd Length: 115  Bit Score: 101.83  E-value: 1.23e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   403 VIVVGFGRFGQVIARLLMANKMrITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLV 482
Cdd:pfam02254   1 IIIIGYGRVGRSLAEELSEGGD-VVVIDKDEERVEELREEGVPVVVGDATDEEVLEEAGIEEADAVIAATGDDEANILIV 79

                          90       100       110
                  ....*....|....*....|....*....|..
gi 16766746   483 ALCQQHFPHLHILARARGRVEAHELLQAGVTQ 514
Cdd:pfam02254  80 LLARELNPDKKIIARANDPEHAELLRRLGADH 111
NhaP COG0025
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
5-317 2.22e-17

NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];


Pssm-ID: 439796 [Multi-domain]  Cd Length: 506  Bit Score: 85.40  E-value: 2.22e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   5 DLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPW-GLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQL 83
Cdd:COG0025   2 ELLLLILLLLLLGLLSQWLARRLKLPAPLLLLLAGILLGPGlGLELDPELGDLEPLLELFLPPLLFEAALNLDLRELRRN 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  84 RRSIFGVGAAQVLLSAAVLAGLLM-LADFLWQAAVVggIGLAMSST--AMALQLMREKGMNR-------SESgqlgfsvl 153
Cdd:COG0025  82 GRPILRLAVVGVLLTTLAVALAAHwLLGLPLAAALL--LGAILAPTdpVAVSPILRRLGVPKrlrtileGES-------- 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 154 LFQDLAVIPALALVplLAGSADEHFDWFKVAMKVLAFAVM-----LIGGrYLLRPVFRFIAASGVREVFTAATLLLVLSA 228
Cdd:COG0025 152 LLNDATALVLFVLA--LAAALGGGFSLGEALLDFLLAILGgilvgLLLG-WLLGRLLRRLPDPLLEILLTLALPFLAYLL 228

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 229 AlfmDALGLSMALGTFIAGVLLAESEYRH---ELENAIDPFKG----LLLGLFFISVGMSLNLGVL-YTHLLWVAASVVI 300
Cdd:COG0025 229 A---EALHGSGVLAVVVAGLVLGNAGRRSlspETRLQLLEFWEtlefLLNSLLFVLLGAQLPLILLgALGLGGILLVLLA 305

                       330
                ....*....|....*..
gi 16766746 301 LVVIKMLTLYLLARLYG 317
Cdd:COG0025 306 LLVVRPLWVFLSLALRG 322
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 335-567 5.03e-16

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 78.96  E-value: 5.03e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 335 EFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPL---LMKGIDKWLSRRLNGPEEN-DEKPWVEDDKPQVIVVGFGR 410
Cdd:COG0569  26 YGLLITLTTVTTLGGGLLDPVTLVAAIFLIGVVIIPLgytLITFGDAVLFGGLLEALRRrRMERGIKKLKMHVIIIGAGR 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746 411 FGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFP 490
Cdd:COG0569 106 VGRSLARELEEEGHDVVVIDKDPERVERLAEEDVLVIVGDATDEEVLEEAGIEDADAVIAATGDDEANILACLLAKELGV 185

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16766746 491 hLHILARARGRVEAHELLQAGVTqfsrETFSSALELGRKTLVSLgMHPHQAQraQLHFRRLDMRMLRELIPEHSDMV 567
Cdd:COG0569 186 -PRIIARANDPEYADLLERLGAD----VVISPERLAARRIARLL-LRPGVLD--VLELADGDAEIVEVTVPEGSPLV 254
PLN03159 PLN03159
cation/H(+) antiporter 15; Provisional
 32-372 3.18e-08

cation/H(+) antiporter 15; Provisional


Pssm-ID: 215608 [Multi-domain]  Cd Length: 832  Bit Score: 56.82  E-value: 3.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746   32 VLGYLLAGIAIGPWGLGFIS----------DVDEILHFSELGVVFLMFIIGLELNpsrLWQLRRSifGVGAAQVLLSAAV 101
Cdd:PLN03159  70 VISEILGGVILGPSVLGQSEvfantifplrSVMVLETMANLGLLYFLFLVGVEMD---ISVIRRT--GKKALAIAIAGMA 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  102 LAGLLMLA---------DFLWQAAVVGGIGLAMSSTAMAL--QLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLL 170
Cdd:PLN03159 145 LPFCIGLAfsfifhqvsRNVHQGTFILFLGVALSVTAFPVlaRILAEIKLINTELGRIAMSAALVNDMCAWILLALAIAL 224

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  171 AGSADEHFDWFKVAMKVLAFAVMLIggrYLLRPVFRFIAAS-----GVREVFTAATLLLVLSAALFMDALGLSMALGTFI 245
Cdd:PLN03159 225 AENDSTSLASLWVLLSSVAFVLFCF---YVVRPGIWWIIRRtpegeTFSEFYICLILTGVMISGFITDAIGTHSVFGAFV 301

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766746  246 AGVLLAESEYRHELENAIDPF-KGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILV--VIKMLTLYLLARLYGIRSSE 322
Cdd:PLN03159 302 FGLVIPNGPLGVTLIEKLEDFvSGLLLPLFFAISGLKTNVTKIQGPATWGLLVLVIIMasAGKIMGTIIIAFFYTMPFRE 381

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 16766746  323 RMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALL-LVTVTLSMMTTPLL 372
Cdd:PLN03159 382 GITLGFLMNTKGLVEMIVLNVGRDQEVLDDESFAVMvLVAVAMTALITPVV 432
trkA PRK09496
Trk system potassium transporter TrkA;
403-469 3.25e-03

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 40.11  E-value: 3.25e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16766746  403 VIVVGFGRFGQVIARLLMANKMRITVLERDIGAVN-LMRKYGYKVYYGDATQVELLRSAGAEAAESIV 469
Cdd:PRK09496   3 IIIVGAGQVGYTLAENLSGENNDVTVIDTDEERLRrLQDRLDVRTVVGNGSSPDVLREAGAEDADLLI 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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