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Concise Results
Standard Results
Full Results
putative xanthine dehydrogenase molybdenum-binding subunit XdhA [Escherichia coli str. K-12 substr. MG1655]
Protein Classification
xanthine dehydrogenase molybdenum-binding subunit XdhA ( domain architecture ID 11484539 )
xanthine dehydrogenase molybdenum-binding subunit XdhA participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism)
List of domain hits
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
1-752
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1440.27
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 1 MRVDAIAKVTGRA R YTDDYVMAGM C YAKYVRSPIAHG YAV SI ND E Q ARSLPGV L A I FTWEDVPDIPF A TAGH A W T LD E N K 80
Cdd:PRK09970 8 MRVDAIAKVTGRA K YTDDYVMAGM L YAKYVRSPIAHG KVK SI DT E E ARSLPGV E A V FTWEDVPDIPF P TAGH P W S LD P N H 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 81 RD T ADRALLTRHVRHHGDAVA I VVARDELTAEKA AQ L VSI E WQ ELPVIT T PEAALAE D A A PIHNG - GNLLKQSTMSTGNV 159
Cdd:PRK09970 88 RD I ADRALLTRHVRHHGDAVA A VVARDELTAEKA LK L IKV E YE ELPVIT D PEAALAE G A P PIHNG r GNLLKQSTMSTGNV 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 160 QQTI D AADYQVQGHY Q TP VI QHCHME S VTS L A W MEDD S RITIVSSTQIPHIVRRVVGQAL D IPW SC VRVIKP F VGGGFGN 239
Cdd:PRK09970 168 QQTI K AADYQVQGHY E TP IV QHCHME N VTS Y A Y MEDD G RITIVSSTQIPHIVRRVVGQAL G IPW GK VRVIKP Y VGGGFGN 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 240 KQDVLEEP M AAFLTSK L GG I PVKVSLSREECFLATRTRHAFTID GQ MGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAG 319
Cdd:PRK09970 248 KQDVLEEP L AAFLTSK V GG R PVKVSLSREECFLATRTRHAFTID IK MGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAG 327
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 320 GNKVAYLYPRCAY A YSSKT C YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE I RLRNAAREGDANPL T GKRIY 399
Cdd:PRK09970 328 GNKVAYLYPRCAY K YSSKT V YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE F RLRNAAREGDANPL S GKRIY 407
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 400 SAGLPECLEKGRKIFEW E KRRAEC Q NQQGNLRRGVGVACFSYTS N TWPVG V EIAGARLLMNQDGT IN VQSGATEIGQG A D 479
Cdd:PRK09970 408 SAGLPECLEKGRKIFEW D KRRAEC K NQQGNLRRGVGVACFSYTS G TWPVG L EIAGARLLMNQDGT VQ VQSGATEIGQG S D 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 480 TVFSQMVAETVG V PVSDVRVISTQDTDVTPFDPGA F ASRQSYVA A PA L R S AAL L LKEKI I AHAAVMLHQSAMNL TL I K GH 559
Cdd:PRK09970 488 TVFSQMVAETVG I PVSDVRVISTQDTDVTPFDPGA Y ASRQSYVA G PA I R K AAL E LKEKI L AHAAVMLHQSAMNL DI I D GH 567
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 560 IV l V E RP E EPLMSL KD LAMDA F YHPERGGQ LS AESSIKTTTNPPAFGCTFVD LT VDIALCKVTINRILNVHDSGHILNPL 639
Cdd:PRK09970 568 IV - V K RP G EPLMSL EE LAMDA Y YHPERGGQ IT AESSIKTTTNPPAFGCTFVD VE VDIALCKVTINRILNVHDSGHILNPL 646
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 640 LAEGQVHGGMGMGIGWALFEEMIID A K S GVVRNPNLLDYK M PTM P DLPQLESAFVEI N EPQSAYGHKSLGEPPII PV A A A 719
Cdd:PRK09970 647 LAEGQVHGGMGMGIGWALFEEMIID E K T GVVRNPNLLDYK L PTM M DLPQLESAFVEI Y EPQSAYGHKSLGEPPII SP A P A 726
730 740 750
....*....|....*....|....*....|...
gi 16130768 720 IRNAV K MATGVAINTLP L TP K RL Y EEF HL AGLI 752
Cdd:PRK09970 727 IRNAV L MATGVAINTLP M TP Q RL F EEF KE AGLI 759
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
1-752
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1440.27
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 1 MRVDAIAKVTGRA R YTDDYVMAGM C YAKYVRSPIAHG YAV SI ND E Q ARSLPGV L A I FTWEDVPDIPF A TAGH A W T LD E N K 80
Cdd:PRK09970 8 MRVDAIAKVTGRA K YTDDYVMAGM L YAKYVRSPIAHG KVK SI DT E E ARSLPGV E A V FTWEDVPDIPF P TAGH P W S LD P N H 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 81 RD T ADRALLTRHVRHHGDAVA I VVARDELTAEKA AQ L VSI E WQ ELPVIT T PEAALAE D A A PIHNG - GNLLKQSTMSTGNV 159
Cdd:PRK09970 88 RD I ADRALLTRHVRHHGDAVA A VVARDELTAEKA LK L IKV E YE ELPVIT D PEAALAE G A P PIHNG r GNLLKQSTMSTGNV 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 160 QQTI D AADYQVQGHY Q TP VI QHCHME S VTS L A W MEDD S RITIVSSTQIPHIVRRVVGQAL D IPW SC VRVIKP F VGGGFGN 239
Cdd:PRK09970 168 QQTI K AADYQVQGHY E TP IV QHCHME N VTS Y A Y MEDD G RITIVSSTQIPHIVRRVVGQAL G IPW GK VRVIKP Y VGGGFGN 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 240 KQDVLEEP M AAFLTSK L GG I PVKVSLSREECFLATRTRHAFTID GQ MGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAG 319
Cdd:PRK09970 248 KQDVLEEP L AAFLTSK V GG R PVKVSLSREECFLATRTRHAFTID IK MGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAG 327
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 320 GNKVAYLYPRCAY A YSSKT C YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE I RLRNAAREGDANPL T GKRIY 399
Cdd:PRK09970 328 GNKVAYLYPRCAY K YSSKT V YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE F RLRNAAREGDANPL S GKRIY 407
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 400 SAGLPECLEKGRKIFEW E KRRAEC Q NQQGNLRRGVGVACFSYTS N TWPVG V EIAGARLLMNQDGT IN VQSGATEIGQG A D 479
Cdd:PRK09970 408 SAGLPECLEKGRKIFEW D KRRAEC K NQQGNLRRGVGVACFSYTS G TWPVG L EIAGARLLMNQDGT VQ VQSGATEIGQG S D 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 480 TVFSQMVAETVG V PVSDVRVISTQDTDVTPFDPGA F ASRQSYVA A PA L R S AAL L LKEKI I AHAAVMLHQSAMNL TL I K GH 559
Cdd:PRK09970 488 TVFSQMVAETVG I PVSDVRVISTQDTDVTPFDPGA Y ASRQSYVA G PA I R K AAL E LKEKI L AHAAVMLHQSAMNL DI I D GH 567
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 560 IV l V E RP E EPLMSL KD LAMDA F YHPERGGQ LS AESSIKTTTNPPAFGCTFVD LT VDIALCKVTINRILNVHDSGHILNPL 639
Cdd:PRK09970 568 IV - V K RP G EPLMSL EE LAMDA Y YHPERGGQ IT AESSIKTTTNPPAFGCTFVD VE VDIALCKVTINRILNVHDSGHILNPL 646
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 640 LAEGQVHGGMGMGIGWALFEEMIID A K S GVVRNPNLLDYK M PTM P DLPQLESAFVEI N EPQSAYGHKSLGEPPII PV A A A 719
Cdd:PRK09970 647 LAEGQVHGGMGMGIGWALFEEMIID E K T GVVRNPNLLDYK L PTM M DLPQLESAFVEI Y EPQSAYGHKSLGEPPII SP A P A 726
730 740 750
....*....|....*....|....*....|...
gi 16130768 720 IRNAV K MATGVAINTLP L TP K RL Y EEF HL AGLI 752
Cdd:PRK09970 727 IRNAV L MATGVAINTLP M TP Q RL F EEF KE AGLI 759
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
2-747
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 820.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 2 RVD AI AKVTGRARYTDD YVMA GM C YA KY VRSP I AH GYAV SI NDEQ A RS LPGV L A IF T W ED V P DIP F ATA G HAWT ldenkr 81
Cdd:COG1529 16 RVD GP AKVTGRARYTDD IRLP GM L YA AV VRSP H AH ARIK SI DTSA A LA LPGV V A VL T G ED L P GLK F GLP G PDPD ------ 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 82 dta DRA L LTRH VR HH G DA VA I VVA RDELT A EK AA Q L VSI E WQE LP VITT PEAALA ED A API H -- NG GN LLKQSTMST G N V 159
Cdd:COG1529 90 --- QPP L ADDK VR YV G EP VA A VVA ETREA A RD AA E L IKV E YEP LP AVVD PEAALA PG A PLV H ee LP GN VAAEWRGER G D V 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 160 QQTIDA AD YQ V QGH Y Q TP VIQ H CH ME SVTSL A WMED D S R I T IVS STQ I PH I VRR VVGQ AL DI P WSC VRVI K P F VGGGFG N 239
Cdd:COG1529 167 DAAFAE AD VV V EAT Y T TP RLA H AP ME PRAAV A EWDG D G R L T VWA STQ G PH L VRR ALAR AL GL P PEK VRVI A P D VGGGFG G 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 240 K Q DV - L EE PM AA FLTS KLG G i PVK VS L S REE C FLA TRT RHA FTIDGQM G VNR DG TLKGYSL DV LSN TGAYAS H G HSIASA 318
Cdd:COG1529 247 K L DV y P EE VL AA LAAR KLG R - PVK LV L T REE D FLA DTH RHA TVQRVRL G ADK DG KITALRH DV VAD TGAYAS F G EAVLPL 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 319 G GNKVAYL Y PRCAYAYSSKTC YTN L P SA GA M RG Y G A PQ VV FA V ES ML D DA A TA LG I DPVE I RLRN AA R E GD AN P l TG KRI 398
Cdd:COG1529 326 G ATMATGP Y AIPNVRVEARAV YTN T P PT GA Y RG P G R PQ AA FA L ES AM D EL A EE LG M DPVE L RLRN LI R P GD FP P - TG QPY 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 399 Y S AG L P ECLEK GRKI F E W EK RRA ECQNQQGNLR RG V GVA CFSYT S N twp V G VEIAG AR LLM N Q DG TIN V QS GAT E IGQG A 478
Cdd:COG1529 405 D S GR L A ECLEK AAEA F G W GE RRA RPAEARAGKL RG I GVA AYIEG S G --- G G GDPES AR VRL N P DG SVT V YT GAT D IGQG H 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 479 D TV FS Q MV AE TV GVP VS DVRV I s TQ DTD V TP FDP G AFA SR QSY V AAP A L R S AA LL L K EK IIAH AA VM L HQSAMN L TLIK G 558
Cdd:COG1529 482 E TV LA Q IA AE EL GVP PE DVRV V - LG DTD L TP YGG G TGG SR STA V GGS A V R K AA EK L R EK LLEL AA HL L GADPED L EFED G 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 559 HIVLVE R P eepl M SL KD LA MD A F Y hperg G Q L S A ESSIKTT T N P - PA FG CTFVDLT VD IALCK V TIN R ILN VHD S G HIL N 637
Cdd:COG1529 561 RVRVPG R S ---- V SL AE LA AA A Y Y ----- G G L E A TGTYDPP T Y P t YS FG AHVAEVE VD PETGE V RVL R VVA VHD C G RVI N 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 638 PLL A EGQV H GG MGM GIG W AL F EE MII D a KS G VVR N P N LL DY KM P TMP D L P QL E SA FVE INE P QSAY G H K SL GEP PI I P VA 717
Cdd:COG1529 632 PLL V EGQV E GG VVQ GIG Q AL Y EE LVY D - ED G QLL N A N FA DY LV P RAA D V P EI E VI FVE TPD P TNPL G A K GV GEP GT I G VA 710
730 740 750
....*....|....*....|....*....|
gi 16130768 718 A AI R NAV KM ATGV A I NT LP L TP KRLYEEFH 747
Cdd:COG1529 711 P AI A NAV YD ATGV R I RD LP I TP EKVLAALR 740
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
409-687
5.19e-93
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 291.36
E-value: 5.19e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 409 K GRKIFEWEK RRAE CQNQ - Q GN LR RG V G V A CFSYT S NTW P VGVEI AGA RLLM N Q DG TIN V QS G A TE I GQG AD T VFS Q MV A 487
Cdd:pfam20256 1 K ALELSDYDE RRAE QAEF n R GN RK RG I G I A PYVEG S GLG P GALNQ AGA LVRL N P DG SVT V YT G G TE M GQG LE T KLA Q IA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 488 E TV G V P VS DVRV IST q DTD VT P FDP G AF ASR QSY V AAP A LRS AA LL L K E KIIAH AA VM L HQ S AMN L TLIK G HIVLVER P E 567
Cdd:pfam20256 81 E AL G I P PE DVRV VEG - DTD TV P NGG G TG ASR STD V GGN A VLL AA EK L R E RLLKI AA HL L EA S PED L EFED G KVYVKGD P R 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 568 E pl MSLKD LA MD A F yhp ER G GQ LSA ESS ----- IK T TTN PP ---- AF G CTFVDLT VD IALCK V TIN R ILN VHD S G HIL NP 638
Cdd:pfam20256 160 S -- VTFAE LA AA A Y --- GE G VG LSA TGF ytppd DE T GQG PP fayy PY G AHAAEVE VD PETGE V RVL R YVA VHD C G RVI NP 234
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 16130768 639 LLA EGQ VH GG MGM GIG W AL F EE MII D a KS G VVRNPN L L DYK M PT MP D L P 687
Cdd:pfam20256 235 AIV EGQ IE GG FVQ GIG L AL M EE LVY D - ED G QLLTAS L M DYK I PT AA D I P 282
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
1-742
9.51e-56
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 207.56
E-value: 9.51e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 1 M RVDAIAKV TG R A R Y T DD YVMAGM - CYAKY V R S PI AH GYA VSI NDEQ A R SLPGV LA I F T W E DVP D I pf A T A G hawtlden 79
Cdd:TIGR02969 581 M HLSGVKHA TG E A I Y C DD MPAVDQ e LFLTF V T S SR AH AKI VSI DLSE A L SLPGV VD I I T A E HLQ D A -- N T F G -------- 650
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 80 krdt ADRA L L T RH V RHH G DA V AI V V A RD E LT A EK AA QL V S I EWQE L - P V I T T P E A A laedaap I HNGGNLLKQSTMST GN 158
Cdd:TIGR02969 651 ---- TEKL L A T DK V HCV G QL V CA V I A DS E VQ A KQ AA KH V K I VYRD L e P L I L T I E E A ------- I QHKSFFEPERKLEY GN 719
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 159 V QQTIDAA D YQVQ G HYQTPVIQ H CH ME SVTS L AWME - D D SRITIVS STQ I P HIVRRV V GQA L DI P WSC V RVIKPF VGG G F 237
Cdd:TIGR02969 720 V DEAFKVV D QILE G EIHMGGQE H FY ME TQSM L VVPK g E D QEMDVYV STQ F P KYIQDI V AAT L KL P VNK V MCHVRR VGG A F 799
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 238 G N K -- QDVLEEPMA AF LTS K l G G IP V KVS L S R E E CF L A T RT RH AFTIDGQM G VNR DG TLKGYSLDVL SN T G AYASHGHSI 315
Cdd:TIGR02969 800 G G K vg KTSIMAAIT AF AAN K - H G RA V RCT L E R G E DM L I T GG RH PYLGKYKA G FMN DG RIVALDVEHY SN G G SSLDESLWV 878
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 316 ASA G GN K V -- AY LY P -- RC ayay SSKT C Y TNLPS AG A M RG Y G A PQ VVFAV E SMLDDA A TAL G ID P VEI R LR N AAR E G D AN 391
Cdd:TIGR02969 879 IEM G LL K M dn AY KF P nl RC ---- RGWA C R TNLPS NT A F RG F G F PQ AGLIT E ACITEV A AKC G LS P EKV R TI N MYK E I D QT 954
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 392 P LT g KR I YSAG L PE C LEKGRKIFEWEK R RAECQ -- N QQGNLR - RG VG V ACFSYTSNTWP V GVEI A G A RLLMNQ DG TIN V Q 468
Cdd:TIGR02969 955 P YK - QE I NAKN L FQ C WRECMAKSSYSE R KVAVE kf N AENYWK k RG LA V IPLKFPVGLGS V AMGQ A A A LVHIYL DG SVL V T 1033
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 469 S G AT E I GQG AD T VFS Q M V AETVGV P V S D V RVIS T QDTD V tpfd P GAF AS RQ S Y VA --- AP A LRS A A - L LLK -- E K II A ha 542
Cdd:TIGR02969 1034 H G GI E M GQG VH T KMI Q V V SRELKM P M S N V HLRG T STET V ---- P NTN AS GG S V VA dln GL A VKD A C q T LLK rl E P II S -- 1107
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 543 avmlhqsamnltlikghivlverp EE P LMSL KD L A MD AF yhp ERGGQ LSA ------- ES S I --- K TTTN P PAF ----- G C 607
Cdd:TIGR02969 1108 ------------------------ KN P QGTW KD W A QT AF --- DQSIS LSA vgyfrgy ES N I nwe K GEGH P FEY fvyga A C 1160
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 608 TF V D --- LT V D IALCKVT I nriln V H D S GH IL NP L L AE GQV H G GMGM G I G WALF EE MIIDAK s G VV -- R N PN ll D YK M P T 682
Cdd:TIGR02969 1161 SE V E idc LT G D HKNIRTD I ----- V M D V GH SI NP A L DI GQV E G AFIQ G M G LYTI EE LSYSPQ - G IL ys R G PN -- Q YK I P A 1232
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16130768 683 MP D L P - Q L ESA F VEIN E - PQSA Y GH K S LGE PPII --- P V AA AI RN AV KM A ------ T G VAIN T L PLTP KRL 742
Cdd:TIGR02969 1233 IC D I P t E L HIS F LPPS E h SNTL Y SS K G LGE SGVF lgc S V FF AI HD AV RA A rqergl S G PWKL T S PLTP EKI 1303
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
10-126
2.81e-37
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 134.95
E-value: 2.81e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 10 TG R ARY T DD YVMA GM CY A KY VRSP I AH GYAV SI NDEQ AR SL PGV L A IF T WE DVP DIPFATAGH awtldenkrd TADRA L L 89
Cdd:smart01008 1 TG E ARY G DD IRLP GM LH A AV VRSP V AH ARIK SI DTSA AR AM PGV V A VL T AK DVP GLNDFGPLG ---------- PDEPV L A 70
90 100 110
....*....|....*....|....*....|....*..
gi 16130768 90 TRH VR HH G DA VA I VVA RD E LT A EK AA QL V SI E WQ ELP 126
Cdd:smart01008 71 DDK VR YV G QP VA A VVA ET E EA A RD AA EA V KV E YE ELP 107
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
1-752
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1440.27
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 1 MRVDAIAKVTGRA R YTDDYVMAGM C YAKYVRSPIAHG YAV SI ND E Q ARSLPGV L A I FTWEDVPDIPF A TAGH A W T LD E N K 80
Cdd:PRK09970 8 MRVDAIAKVTGRA K YTDDYVMAGM L YAKYVRSPIAHG KVK SI DT E E ARSLPGV E A V FTWEDVPDIPF P TAGH P W S LD P N H 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 81 RD T ADRALLTRHVRHHGDAVA I VVARDELTAEKA AQ L VSI E WQ ELPVIT T PEAALAE D A A PIHNG - GNLLKQSTMSTGNV 159
Cdd:PRK09970 88 RD I ADRALLTRHVRHHGDAVA A VVARDELTAEKA LK L IKV E YE ELPVIT D PEAALAE G A P PIHNG r GNLLKQSTMSTGNV 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 160 QQTI D AADYQVQGHY Q TP VI QHCHME S VTS L A W MEDD S RITIVSSTQIPHIVRRVVGQAL D IPW SC VRVIKP F VGGGFGN 239
Cdd:PRK09970 168 QQTI K AADYQVQGHY E TP IV QHCHME N VTS Y A Y MEDD G RITIVSSTQIPHIVRRVVGQAL G IPW GK VRVIKP Y VGGGFGN 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 240 KQDVLEEP M AAFLTSK L GG I PVKVSLSREECFLATRTRHAFTID GQ MGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAG 319
Cdd:PRK09970 248 KQDVLEEP L AAFLTSK V GG R PVKVSLSREECFLATRTRHAFTID IK MGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAG 327
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 320 GNKVAYLYPRCAY A YSSKT C YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE I RLRNAAREGDANPL T GKRIY 399
Cdd:PRK09970 328 GNKVAYLYPRCAY K YSSKT V YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE F RLRNAAREGDANPL S GKRIY 407
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 400 SAGLPECLEKGRKIFEW E KRRAEC Q NQQGNLRRGVGVACFSYTS N TWPVG V EIAGARLLMNQDGT IN VQSGATEIGQG A D 479
Cdd:PRK09970 408 SAGLPECLEKGRKIFEW D KRRAEC K NQQGNLRRGVGVACFSYTS G TWPVG L EIAGARLLMNQDGT VQ VQSGATEIGQG S D 487
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 480 TVFSQMVAETVG V PVSDVRVISTQDTDVTPFDPGA F ASRQSYVA A PA L R S AAL L LKEKI I AHAAVMLHQSAMNL TL I K GH 559
Cdd:PRK09970 488 TVFSQMVAETVG I PVSDVRVISTQDTDVTPFDPGA Y ASRQSYVA G PA I R K AAL E LKEKI L AHAAVMLHQSAMNL DI I D GH 567
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 560 IV l V E RP E EPLMSL KD LAMDA F YHPERGGQ LS AESSIKTTTNPPAFGCTFVD LT VDIALCKVTINRILNVHDSGHILNPL 639
Cdd:PRK09970 568 IV - V K RP G EPLMSL EE LAMDA Y YHPERGGQ IT AESSIKTTTNPPAFGCTFVD VE VDIALCKVTINRILNVHDSGHILNPL 646
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 640 LAEGQVHGGMGMGIGWALFEEMIID A K S GVVRNPNLLDYK M PTM P DLPQLESAFVEI N EPQSAYGHKSLGEPPII PV A A A 719
Cdd:PRK09970 647 LAEGQVHGGMGMGIGWALFEEMIID E K T GVVRNPNLLDYK L PTM M DLPQLESAFVEI Y EPQSAYGHKSLGEPPII SP A P A 726
730 740 750
....*....|....*....|....*....|...
gi 16130768 720 IRNAV K MATGVAINTLP L TP K RL Y EEF HL AGLI 752
Cdd:PRK09970 727 IRNAV L MATGVAINTLP M TP Q RL F EEF KE AGLI 759
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
2-747
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 820.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 2 RVD AI AKVTGRARYTDD YVMA GM C YA KY VRSP I AH GYAV SI NDEQ A RS LPGV L A IF T W ED V P DIP F ATA G HAWT ldenkr 81
Cdd:COG1529 16 RVD GP AKVTGRARYTDD IRLP GM L YA AV VRSP H AH ARIK SI DTSA A LA LPGV V A VL T G ED L P GLK F GLP G PDPD ------ 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 82 dta DRA L LTRH VR HH G DA VA I VVA RDELT A EK AA Q L VSI E WQE LP VITT PEAALA ED A API H -- NG GN LLKQSTMST G N V 159
Cdd:COG1529 90 --- QPP L ADDK VR YV G EP VA A VVA ETREA A RD AA E L IKV E YEP LP AVVD PEAALA PG A PLV H ee LP GN VAAEWRGER G D V 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 160 QQTIDA AD YQ V QGH Y Q TP VIQ H CH ME SVTSL A WMED D S R I T IVS STQ I PH I VRR VVGQ AL DI P WSC VRVI K P F VGGGFG N 239
Cdd:COG1529 167 DAAFAE AD VV V EAT Y T TP RLA H AP ME PRAAV A EWDG D G R L T VWA STQ G PH L VRR ALAR AL GL P PEK VRVI A P D VGGGFG G 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 240 K Q DV - L EE PM AA FLTS KLG G i PVK VS L S REE C FLA TRT RHA FTIDGQM G VNR DG TLKGYSL DV LSN TGAYAS H G HSIASA 318
Cdd:COG1529 247 K L DV y P EE VL AA LAAR KLG R - PVK LV L T REE D FLA DTH RHA TVQRVRL G ADK DG KITALRH DV VAD TGAYAS F G EAVLPL 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 319 G GNKVAYL Y PRCAYAYSSKTC YTN L P SA GA M RG Y G A PQ VV FA V ES ML D DA A TA LG I DPVE I RLRN AA R E GD AN P l TG KRI 398
Cdd:COG1529 326 G ATMATGP Y AIPNVRVEARAV YTN T P PT GA Y RG P G R PQ AA FA L ES AM D EL A EE LG M DPVE L RLRN LI R P GD FP P - TG QPY 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 399 Y S AG L P ECLEK GRKI F E W EK RRA ECQNQQGNLR RG V GVA CFSYT S N twp V G VEIAG AR LLM N Q DG TIN V QS GAT E IGQG A 478
Cdd:COG1529 405 D S GR L A ECLEK AAEA F G W GE RRA RPAEARAGKL RG I GVA AYIEG S G --- G G GDPES AR VRL N P DG SVT V YT GAT D IGQG H 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 479 D TV FS Q MV AE TV GVP VS DVRV I s TQ DTD V TP FDP G AFA SR QSY V AAP A L R S AA LL L K EK IIAH AA VM L HQSAMN L TLIK G 558
Cdd:COG1529 482 E TV LA Q IA AE EL GVP PE DVRV V - LG DTD L TP YGG G TGG SR STA V GGS A V R K AA EK L R EK LLEL AA HL L GADPED L EFED G 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 559 HIVLVE R P eepl M SL KD LA MD A F Y hperg G Q L S A ESSIKTT T N P - PA FG CTFVDLT VD IALCK V TIN R ILN VHD S G HIL N 637
Cdd:COG1529 561 RVRVPG R S ---- V SL AE LA AA A Y Y ----- G G L E A TGTYDPP T Y P t YS FG AHVAEVE VD PETGE V RVL R VVA VHD C G RVI N 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 638 PLL A EGQV H GG MGM GIG W AL F EE MII D a KS G VVR N P N LL DY KM P TMP D L P QL E SA FVE INE P QSAY G H K SL GEP PI I P VA 717
Cdd:COG1529 632 PLL V EGQV E GG VVQ GIG Q AL Y EE LVY D - ED G QLL N A N FA DY LV P RAA D V P EI E VI FVE TPD P TNPL G A K GV GEP GT I G VA 710
730 740 750
....*....|....*....|....*....|
gi 16130768 718 A AI R NAV KM ATGV A I NT LP L TP KRLYEEFH 747
Cdd:COG1529 711 P AI A NAV YD ATGV R I RD LP I TP EKVLAALR 740
PRK09800
PRK09800 putative hypoxanthine oxidase; Provisional
2-742
4.90e-128
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain]
Cd Length: 956
Bit Score: 404.60
E-value: 4.90e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 2 RV DA IAK V TGRAR Y TD D Y V M A GM C YA K YV RSP I AH GYAVSINDEQ A RS LPGV LAIF T WEDV PDI PFATA G HAWT lden KR 81
Cdd:PRK09800 178 KT DA AKM V QAKPC Y VE D R V T A DA C VI K ML RSP H AH ALITHLDVSK A EA LPGV VHVI T HLNC PDI YYTPG G QSAP ---- EP 253
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 82 DTA DR ALLTRHV RH H GD A VA I VVA RD E LT A EK A AQ L VSI E WQE L PVITTPEA A L AEDA API H NG ---------------- 145
Cdd:PRK09800 254 SPL DR RMFGKKM RH V GD R VA A VVA ES E EI A LE A LK L IDV E YEV L KPVMSIDE A M AEDA PVV H DE pvvyvagapdtleddn 333
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 146 --------------------- G N LLKQSTMST G NVQQTIDA AD YQVQGH Y QTPVI Q H C HM E SVTSLAW M e D DS R IT I VS S 204
Cdd:PRK09800 334 shaaqrgehmiinfpigsrpr K N IAASIHGHI G DMDKGFAD AD VIIERT Y NSTQA Q Q C PT E THICFTR M - D GD R LV I HA S 412
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 205 TQ I P HIV RR V V GQALDIPWSC V R VIK PF VGGGFG N KQD V L E E PMA A FL T s KLG G I PV KVSLS REE C F L A TRT RH AFTIDG 284
Cdd:PRK09800 413 TQ V P WHL RR Q V ARLVGMKQHK V H VIK ER VGGGFG S KQD I L L E EVC A WA T - CVT G R PV LFRYT REE E F I A NTS RH VAKVTV 491
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 285 QM G VNR DG T L KGYSL D VLS NTG A Y AS H GHSIASA G GNKVAY LYP RCAYAYSSK T C Y T N LPSA GA MR GYGAP QVV FA VESM 364
Cdd:PRK09800 492 KL G AKK DG R L TAVKM D FRA NTG P Y GN H SLTVPCN G PALSLP LYP CDNVDFQVT T Y Y S N ICPN GA YQ GYGAP KGN FA ITMA 571
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 365 L DDA A TA L G ID PV EI RL RN AAR EG D ----------- AN P LTGKRIY S AG L P E C L EK GR KIFE W EKRRA ecqn Q Q G NLRR G 433
Cdd:PRK09800 572 L AEL A EQ L Q ID QL EI IE RN RVH EG Q elkilgaigeg KA P TSVPSAA S CA L E E I L RQ GR EMIQ W SSPKP ---- Q N G DWHI G 647
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 434 V GVA CFSYT S NT w P v GVEI A GARLLMNQ DGT IN V Q SG ATE IG Q G A DTV FSQMV AE TVGV P VS DV R VIS T q DTD VTP FD P G 513
Cdd:PRK09800 648 R GVA IIMQK S GI - P - DIDQ A NCMIKLES DGT FI V H SG GAD IG T G L DTV VTKLA AE VLHC P PQ DV H VIS G - DTD HAL FD K G 724
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 514 A F AS RQSYVAAP A L R S AA LL L K EKI IA H A A V ML HQSAMNLT L IKGHI V LVERP E epl M S LK D L A MDA fyhp E R G --- G Q L 590
Cdd:PRK09800 725 A Y AS SGTCFSGN A A R L AA EN L R EKI LF H G A Q ML GEPVADVQ L ATPGV V RGKKG E --- V S FG D I A HKG ---- E T G tgf G S L 797
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 591 SAES S IK T TTNPPAF G CT F VDLT V DIALCKVTINRILNVH D S G HIL NP L LA E GQ VH G GMGMG IG WALF EE M I I DA K s G VV 670
Cdd:PRK09800 798 VGTG S YI T PDFAFPY G AN F AEVA V NTRTGEIRLDKFYALL D C G TPV NP E LA L GQ IY G ATLRA IG HSMS EE I I Y DA E - G HP 876
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16130768 671 RNPN L LD Y KM P TMP D L P QLES A F - V EINEPQSAY G H KS LG E PPIIPV A A AI RN A VKM A T G VAINTLPL TP KRL 742
Cdd:PRK09800 877 LTRD L RS Y GA P KIG D I P RDFR A V l V PSDDKVGPF G A KS IS E IGVNGA A P AI AT A IHD A C G IWLREWHF TP EKI 949
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
409-687
5.19e-93
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 291.36
E-value: 5.19e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 409 K GRKIFEWEK RRAE CQNQ - Q GN LR RG V G V A CFSYT S NTW P VGVEI AGA RLLM N Q DG TIN V QS G A TE I GQG AD T VFS Q MV A 487
Cdd:pfam20256 1 K ALELSDYDE RRAE QAEF n R GN RK RG I G I A PYVEG S GLG P GALNQ AGA LVRL N P DG SVT V YT G G TE M GQG LE T KLA Q IA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 488 E TV G V P VS DVRV IST q DTD VT P FDP G AF ASR QSY V AAP A LRS AA LL L K E KIIAH AA VM L HQ S AMN L TLIK G HIVLVER P E 567
Cdd:pfam20256 81 E AL G I P PE DVRV VEG - DTD TV P NGG G TG ASR STD V GGN A VLL AA EK L R E RLLKI AA HL L EA S PED L EFED G KVYVKGD P R 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 568 E pl MSLKD LA MD A F yhp ER G GQ LSA ESS ----- IK T TTN PP ---- AF G CTFVDLT VD IALCK V TIN R ILN VHD S G HIL NP 638
Cdd:pfam20256 160 S -- VTFAE LA AA A Y --- GE G VG LSA TGF ytppd DE T GQG PP fayy PY G AHAAEVE VD PETGE V RVL R YVA VHD C G RVI NP 234
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 16130768 639 LLA EGQ VH GG MGM GIG W AL F EE MII D a KS G VVRNPN L L DYK M PT MP D L P 687
Cdd:pfam20256 235 AIV EGQ IE GG FVQ GIG L AL M EE LVY D - ED G QLLTAS L M DYK I PT AA D I P 282
MoCoBD_1
pfam02738 Molybdopterin cofactor-binding domain;
157-384
9.60e-89
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain]
Cd Length: 244
Bit Score: 278.95
E-value: 9.60e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 157 G N V QQTIDA AD YQ V Q G H Y Q T PVIQ H CH ME SVTS LA - WMED D S R I T IV SSTQ I PH I VRR V V GQA L D IP WSC VRVI K P F VGG 235
Cdd:pfam02738 16 G D V EAAFAE AD HV V E G E Y R T GRQE H FY ME TRAA LA v PDDE D G R L T VY SSTQ G PH L VRR L V ARV L G IP ENK VRVI V P R VGG 95
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 236 GFG N K - Q DVL EE PM AA FLTS K L G G i PVK VS L S REE CF LAT RT RH A F T I DGQM G VNR DG TLKGYSL D VLSNT GAYA SHGHS 314
Cdd:pfam02738 96 GFG G K t Q SYP EE AL AA LAAR K T G R - PVK WV L D REE DM LAT GH RH P F L I KYKV G ADK DG KILALDV D LYADG GAYA DLSPA 174
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 315 IASAGGNKVAYL Y PRCAYAYSSKTC YTN L P SA GA M RG Y G A PQ VV FA V E SML D DA A TA LG I DP V E I R L RN A 384
Cdd:pfam02738 175 VPERALSHLDGP Y KIPNVRVDGRAV YTN T P PN GA F RG F G R PQ GM FA L E RLM D EL A EE LG M DP L E L R R RN L 244
PLN02906
PLN02906 xanthine dehydrogenase
9-742
7.97e-70
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain]
Cd Length: 1319
Bit Score: 249.62
E-value: 7.97e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 9 VTG R A R Y T DD YV M - AGMCY A KY V R S PIA H GYAV SI N D EQ A R S L PG VLA IF TWE DVP --- D I pfata G HAW t L DE nkrdta 84
Cdd:PLN02906 578 VTG E A E Y A DD IP M p PNTLH A AL V L S TKP H ARIL SI D D SE A K S S PG FAG IF LAK DVP gdn M I ----- G PVV - H DE ------ 645
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 85 d RALL T RH V RHH G DAVAI VVA RDELT A EK AA QL V SI E WQ ELP V I TTP E A A L ae D A API H NG gnll KQSTMST G N V QQTID 164
Cdd:PLN02906 646 - ELFA T DV V TCV G QVIGV VVA DTQEN A KA AA RK V KV E YE ELP A I LSI E E A I -- E A GSF H PN ---- TERRLEK G D V ELCFA 718
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 165 -- AA D YQVQ G HY Q TPVIQ H CHM E SVT SL A W - MEDDSRITIV SSTQ I P HIVRRV V GQA L DI P W S C V RVIKPFV GGGFG N K q 241
Cdd:PLN02906 719 sg QC D RIIE G EV Q MGGQE H FYL E PNS SL V W t SDSGNEVHMI SSTQ A P QKHQKY V AHV L GL P M S K V VCKTKRI GGGFG G K - 797
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 242 dvle E PMA AF LT ------ SK L GGI PVK VS L S R EECFLA T RT RHAF TIDGQM G VNRD G TLKGYS L DVLS N T G AYASHGHSI 315
Cdd:PLN02906 798 ---- E TRS AF IA aaaavp AY L LNR PVK LT L D R DVDMMI T GQ RHAF LGKYKV G FTNE G KILALD L EIYN N G G NSLDLSGAV 873
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 316 A saggn KV A YLYPRCA Y AYSS ----- KT C Y TN L PS AG A M RG Y G A PQ VVFAV E SMLDDA A TA L GID P V EIR LR N AAR EG DA 390
Cdd:PLN02906 874 L ----- ER A MFHSDNV Y EIPN vrivg NV C F TN F PS NT A F RG F G G PQ GMLIT E NWIQRI A VE L NKS P E EIR EM N FQG EG SV 948
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 391 NPL t G KRIYSAG LP ECLEKGRKIFEWE KRR A E C --- QNQQGNLR RGV GVA cfsytsntw P VGVE I AGARLL MNQ ------ 461
Cdd:PLN02906 949 THY - G QVLQHCT LP QLWDELKVSCDFL KRR E E V def NAKNRWKK RGV AMV --------- P TKFG I SFTTKF MNQ agalvh 1018
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 462 --- DGT IN V QS G AT E I GQG AD T VFS Q MV A ETVGV P V S D V r V IS TQD TD VT P -- FDPG A F AS RQS Y V A apalrs A A L LLK E 536
Cdd:PLN02906 1019 vyt DGT VL V TH G GV E M GQG LH T KVA Q VA A SAFNI P L S S V - F IS ETS TD KV P na SPTA A S AS SDM Y G A ------ A V L DAC E 1091
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 537 K I I A HAAVM lhqsamnltlikghivlve RPEEPLM S LKD L AMDAFY hp E R g GQ LSA --------- ESSI KT TTNP P ---- 603
Cdd:PLN02906 1092 Q I K A RMEPV ------------------- ASKLNFS S FAE L VTACYF -- Q R - ID LSA hgfyitpdi GFDW KT GKGN P fnyf 1149
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 604 AF G CT F VD ----- LT V D IALCK V T I nriln V H D S G HIL NP LLAE GQ VH G GMGM G I GW ALF EE MII - DA KSGVV R NPN L L - 676
Cdd:PLN02906 1150 TY G AA F AE veidt LT G D FHTRR V D I ----- V M D L G YSI NP AIDI GQ IE G AFVQ G L GW VAL EE LKW g DA AHKWI R PGS L F t 1224
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 677 ---- D YK M P TMP D L P Q ------ L ES A fvei NE P QSAYGH K SL GEPP IIPV A A --- AI RN A V K M A - TG V AINT ----- L P L 737
Cdd:PLN02906 1225 cgpg T YK I P SVN D I P F kfnvsl L KG A ---- PN P KAIHSS K AV GEPP FFLA A S vff AI KD A I K A A r AE V GLHG wfpld T P A 1300
....*
gi 16130768 738 TP K R L 742
Cdd:PLN02906 1301 TP E R I 1305
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
1-742
9.51e-56
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 207.56
E-value: 9.51e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 1 M RVDAIAKV TG R A R Y T DD YVMAGM - CYAKY V R S PI AH GYA VSI NDEQ A R SLPGV LA I F T W E DVP D I pf A T A G hawtlden 79
Cdd:TIGR02969 581 M HLSGVKHA TG E A I Y C DD MPAVDQ e LFLTF V T S SR AH AKI VSI DLSE A L SLPGV VD I I T A E HLQ D A -- N T F G -------- 650
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 80 krdt ADRA L L T RH V RHH G DA V AI V V A RD E LT A EK AA QL V S I EWQE L - P V I T T P E A A laedaap I HNGGNLLKQSTMST GN 158
Cdd:TIGR02969 651 ---- TEKL L A T DK V HCV G QL V CA V I A DS E VQ A KQ AA KH V K I VYRD L e P L I L T I E E A ------- I QHKSFFEPERKLEY GN 719
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 159 V QQTIDAA D YQVQ G HYQTPVIQ H CH ME SVTS L AWME - D D SRITIVS STQ I P HIVRRV V GQA L DI P WSC V RVIKPF VGG G F 237
Cdd:TIGR02969 720 V DEAFKVV D QILE G EIHMGGQE H FY ME TQSM L VVPK g E D QEMDVYV STQ F P KYIQDI V AAT L KL P VNK V MCHVRR VGG A F 799
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 238 G N K -- QDVLEEPMA AF LTS K l G G IP V KVS L S R E E CF L A T RT RH AFTIDGQM G VNR DG TLKGYSLDVL SN T G AYASHGHSI 315
Cdd:TIGR02969 800 G G K vg KTSIMAAIT AF AAN K - H G RA V RCT L E R G E DM L I T GG RH PYLGKYKA G FMN DG RIVALDVEHY SN G G SSLDESLWV 878
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 316 ASA G GN K V -- AY LY P -- RC ayay SSKT C Y TNLPS AG A M RG Y G A PQ VVFAV E SMLDDA A TAL G ID P VEI R LR N AAR E G D AN 391
Cdd:TIGR02969 879 IEM G LL K M dn AY KF P nl RC ---- RGWA C R TNLPS NT A F RG F G F PQ AGLIT E ACITEV A AKC G LS P EKV R TI N MYK E I D QT 954
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 392 P LT g KR I YSAG L PE C LEKGRKIFEWEK R RAECQ -- N QQGNLR - RG VG V ACFSYTSNTWP V GVEI A G A RLLMNQ DG TIN V Q 468
Cdd:TIGR02969 955 P YK - QE I NAKN L FQ C WRECMAKSSYSE R KVAVE kf N AENYWK k RG LA V IPLKFPVGLGS V AMGQ A A A LVHIYL DG SVL V T 1033
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 469 S G AT E I GQG AD T VFS Q M V AETVGV P V S D V RVIS T QDTD V tpfd P GAF AS RQ S Y VA --- AP A LRS A A - L LLK -- E K II A ha 542
Cdd:TIGR02969 1034 H G GI E M GQG VH T KMI Q V V SRELKM P M S N V HLRG T STET V ---- P NTN AS GG S V VA dln GL A VKD A C q T LLK rl E P II S -- 1107
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 543 avmlhqsamnltlikghivlverp EE P LMSL KD L A MD AF yhp ERGGQ LSA ------- ES S I --- K TTTN P PAF ----- G C 607
Cdd:TIGR02969 1108 ------------------------ KN P QGTW KD W A QT AF --- DQSIS LSA vgyfrgy ES N I nwe K GEGH P FEY fvyga A C 1160
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 608 TF V D --- LT V D IALCKVT I nriln V H D S GH IL NP L L AE GQV H G GMGM G I G WALF EE MIIDAK s G VV -- R N PN ll D YK M P T 682
Cdd:TIGR02969 1161 SE V E idc LT G D HKNIRTD I ----- V M D V GH SI NP A L DI GQV E G AFIQ G M G LYTI EE LSYSPQ - G IL ys R G PN -- Q YK I P A 1232
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16130768 683 MP D L P - Q L ESA F VEIN E - PQSA Y GH K S LGE PPII --- P V AA AI RN AV KM A ------ T G VAIN T L PLTP KRL 742
Cdd:TIGR02969 1233 IC D I P t E L HIS F LPPS E h SNTL Y SS K G LGE SGVF lgc S V FF AI HD AV RA A rqergl S G PWKL T S PLTP EKI 1303
PLN00192
PLN00192 aldehyde oxidase
5-727
6.71e-41
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain]
Cd Length: 1344
Bit Score: 162.19
E-value: 6.71e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 5 A I A KV ------ T G R A R Y T DD YVMAGM C - Y AKYVR S PIAHGYAVS I NDEQARSLP GVLA IF T WE D V P dipfa TA G hawtld 77
Cdd:PLN00192 582 P I K KV gaalqa S G E A V Y V DD IPSPKN C l Y GAFIY S TKPLARVKG I KFKSNLVPQ GVLA VI T FK D I P ----- KG G ------ 650
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 78 E N --- K RDTADRA L LTRH V RHH - G DAV A I VVA RDELT A EK AA Q L VSI E WQ ---- E L P VI T TPE A alaedaapihnggnl L 149
Cdd:PLN00192 651 Q N igs K TIFGPEP L FADE V TRC a G QRI A L VVA DTQKH A DM AA N L AVV E YD tenl E P P IL T VED A --------------- V 715
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 150 K Q S TM ---------- ST G NVQQTIDA AD YQVQGHYQTPVI Q - HCH ME SV T S LA WMED D SR I TIV SSTQ I P HI V RR V VGQA 218
Cdd:PLN00192 716 K R S SL fevppflypk PV G DISKGMAE AD HKILSAEIKLGS Q y YFY ME TQ T A LA LPDE D NC I VVY SSTQ C P EY V HS V IARC 795
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 219 L D IP WSC VRVI KPF VGGGFG N K Q d V LEE P M A --- A FLTS KL GG i PV KVS L S R EECFLATRT RH AFT I DGQM G VNR DG TLK 295
Cdd:PLN00192 796 L G IP EHN VRVI TRR VGGGFG G K A - V KSM P V A tac A LAAF KL QR - PV RMY L N R KTDMIMAGG RH PMK I TYSV G FKS DG KIT 873
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 296 GYS LD V L S N T G AYASHGHSIAS agg N KVAY L -- Y PRC A YAYSS K T C Y TNL P S AG AMR GY G AP Q VVFAV E SMLDDA A TA L G 373
Cdd:PLN00192 874 ALH LD I L I N A G ISPDISPIMPR --- N IIGA L kk Y DWG A LSFDI K V C K TNL S S RS AMR AP G EV Q GSYIA E AIIEHV A ST L S 950
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 374 I D PVEI R LR N AA reg DANP L tg K RI Y SAGLP E CL E KGRKIF e W E K -------- R R A E CQNQ -- QG N LRRGV G VAC ---- F 439
Cdd:PLN00192 951 M D VDSV R KI N LH --- TYES L -- K LF Y GDSAG E PS E YTLPSI - W D K lasssefk Q R T E MVKE fn RS N KWKKR G ISR vpiv H 1024
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 440 SYTSNTW P VG V E I agarll MN q DG T I N V QS G AT EIGQG AD T VFS QM V A -------- ETVGVPVSDV RVI S tqd T D VTPFD 511
Cdd:PLN00192 1025 EVMLRPT P GK V S I ------ LS - DG S I A V EV G GI EIGQG LW T KVK QM A A fglgmikc DGGEDLLDKI RVI Q --- S D TLSMI 1094
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 512 P G A F -- A S RQ S YVAAP A L R SAALL L K E K iiahaavm L HQSAMN L TLIK G HIVLVERPEEPL M SLKD L AMDAF Y H P E rggq 589
Cdd:PLN00192 1095 Q G G F ta G S TT S ESSCE A V R LCCVI L V E R -------- L KPIKER L QEQM G SVTWDMLISQAY M QSVN L SASSY Y T P D ---- 1162
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 590 lsaessi KTTTNPPAF G CTFVDLT VD IALCKV TI N R ILNVH D S G HI LNP LLAE GQ VH G GMGM GIG WALF EE MIIDAK s G V 669
Cdd:PLN00192 1163 ------- PSSMEYLNY G AAVSEVE VD LLTGET TI L R SDIIY D C G QS LNP AVDL GQ IE G AFVQ GIG FFML EE YTTNSD - G L 1234
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16130768 670 V RNPNLLD YK M PT MPDL P Q les A F - VEI N ep Q S AYGH ------ K SL GEPP II --- P V AA A I R N A VKM A 727
Cdd:PLN00192 1235 V VTDGTWT YK I PT VDTI P K --- Q F n VEI L -- N S GHHK krvlss K AS GEPP LL laa S V HC A T R A A IRE A 1297
Ald_Xan_dh_C
pfam01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
10-126
5.05e-39
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain]
Cd Length: 107
Bit Score: 139.68
E-value: 5.05e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 10 TG R A R Y T DD YVMA G MC Y AKY VRS P IAH GYA VSI NDEQ A RS LPGV L A IF T WE D V P DIPFATAGHA wtldenkrdt A D RALL 89
Cdd:pfam01315 1 TG E A V Y V DD IPAP G NL Y GAF VRS T IAH AKI VSI DTSA A LA LPGV V A VI T AK D L P GGNYNIGPIP ---------- L D PLFA 70
90 100 110
....*....|....*....|....*....|....*..
gi 16130768 90 T RH VRH H G DAV A I VVA R DE L TA EK AA Q LV SI E WQ ELP 126
Cdd:pfam01315 71 T DK VRH V G QPI A A VVA D DE E TA RR AA K LV KV E YE ELP 107
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
10-126
2.81e-37
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 134.95
E-value: 2.81e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16130768 10 TG R ARY T DD YVMA GM CY A KY VRSP I AH GYAV SI NDEQ AR SL PGV L A IF T WE DVP DIPFATAGH awtldenkrd TADRA L L 89
Cdd:smart01008 1 TG E ARY G DD IRLP GM LH A AV VRSP V AH ARIK SI DTSA AR AM PGV V A VL T AK DVP GLNDFGPLG ---------- PDEPV L A 70
90 100 110
....*....|....*....|....*....|....*..
gi 16130768 90 TRH VR HH G DA VA I VVA RD E LT A EK AA QL V SI E WQ ELP 126
Cdd:smart01008 71 DDK VR YV G QP VA A VVA ET E EA A RD AA EA V KV E YE ELP 107
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
