|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
1-510 |
0e+00 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 1082.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 1 MSNIDIEGILKELPNDG-RTPKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILA 79
Cdd:PLN02461 1 MANIDIEGILKGLPADGlRRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 80 AVMLDTKGPEIRTGFLKDGNPIQLKEGQEITITTDYDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNA 159
Cdd:PLN02461 81 AVMLDTKGPEIRTGFLKDGKPVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 160 GTVICRCENTAMLGERKNVNLPGVVVDLPTLTDKDVEDILKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMS 239
Cdd:PLN02461 161 GTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDILQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLIS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 240 KVENQEGVLNFDEILRETDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 319
Cdd:PLN02461 241 KVENQEGLDNFDDILAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 320 NAVLDGTDCVMLSGESAAGAYPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMSTLESLASSAVRTANKAKAKLII 399
Cdd:PLN02461 321 NAVLDGTDCVMLSGETAAGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSPLESLASSAVRTANKVKASLIV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 400 VLTRGGTTAKLVAKYRPAVPILSVVVPVFTSDTFNWSCSDESPARHSLIYRGLIPVLGEGSAKATDSESTEEIIESALKS 479
Cdd:PLN02461 401 VLTRGGTTARLVAKYRPAVPILSVVVPEITTDSFDWSCSDEAPARHSLIYRGLIPVLAEGSAKATDSESTEEILEAAIEH 480
|
490 500 510
....*....|....*....|....*....|.
gi 15242863 480 ATEKGLCNHGDAVVALHRIGAASVIKICVVK 510
Cdd:PLN02461 481 AKKKGLCKPGDSVVALHRIGGASVIKILTVK 511
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
20-509 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 726.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 20 PKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGN 99
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 100 PIQLKEGQEITITTDY-DIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNAgTVICRCENTAMLGERKNV 178
Cdd:cd00288 82 DISLKAGDKFLVTTDPaAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDK-TLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 179 NLPGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMSKVENQEGVLNFDEILRETD 258
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADL-RFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 259 AFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 338
Cdd:cd00288 240 GIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 339 AYPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAV 418
Cdd:cd00288 320 KYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 419 PILSVvvpvftsdTFNwscsdESPARHSLIYRGLIPVLGEgSAKATDSESTEEIIESALKSATEKGLCNHGDAVVALHRI 498
Cdd:cd00288 400 PIIAV--------TRN-----EQTARQLHLYRGVYPVLFE-EPKPGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGW 465
|
490
....*....|....*
gi 15242863 499 ----GAASVIKICVV 509
Cdd:cd00288 466 pvgsGSTNTMRILTV 480
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
21-509 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 638.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 21 KTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:COG0469 4 RTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG-P 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 101 IQLKEGQEITITTDyDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNAgtVICRCENTAMLGERKNVNL 180
Cdd:COG0469 83 VELKKGDTFTLTTD-DVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDE--VVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 181 PGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMSKVENQEGVLNFDEILRETDAF 260
Cdd:COG0469 160 PGVGLSLPALTEKDREDL-KFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 261 MVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAY 340
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 341 PEIAVKTMAKICIEAESSLDYNTIFKEmiRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAVPI 420
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRRILDR--LRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPI 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 421 LSVvvpvftsdtfnwsCSDESPARHSLIYRGLIPVLGEgsakatDSESTEEIIESALKSATEKGLCNHGDAVV-----AL 495
Cdd:COG0469 397 LAL-------------TPNERTARRLALVWGVYPVLVD------DVESTDEMIEEAVEALLEEGLVKPGDLVVitagvPV 457
|
490
....*....|....
gi 15242863 496 HRIGAASVIKICVV 509
Cdd:COG0469 458 GVPGTTNTLKVHRV 471
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
21-503 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 564.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 21 KTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:TIGR01064 2 RTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGG-E 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 101 IQLKEGQEITITTDYDIK-GDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNagTVICRCENTAMLGERKNVN 179
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKGeGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGD--KVICEVLNGGTLKSKKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 180 LPGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSH-SKSIMLMSKVENQEGVLNFDEILRETD 258
Cdd:TIGR01064 159 LPGADVDLPALSEKDKKDL-KFGVEQGVDMVAASFVRTAEDVLEVREVLGEKgAKDVKIIAKIENQEGVDNIDEIAEASD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 259 AFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 338
Cdd:TIGR01064 238 GIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 339 AYPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAV 418
Cdd:TIGR01064 318 KYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 419 PILSVVVpvftsdtfnwscsDESPARHSLIYRGLIPVLGEGSAkatdsESTEEIIESALKSATEKGLCNHGDAVVALHRI 498
Cdd:TIGR01064 398 PIIAVTP-------------NERVARQLALYWGVFPFLVDEEP-----SDTDARVNKALELLKEKGIVKKGDLVVVIQGG 459
|
....*
gi 15242863 499 GAASV 503
Cdd:TIGR01064 460 PIGGE 464
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
20-365 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 562.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 20 PKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDG- 98
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 99 NPIQLKEGQEITITTDYDIKG--DEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPnAGTVICRCENTAMLGERK 176
Cdd:pfam00224 82 KDIELKAGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDD-DKTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 177 NVNLPGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMSKVENQEGVLNFDEILRE 256
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADL-RFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 257 TDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESA 336
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*....
gi 15242863 337 AGAYPEIAVKTMAKICIEAESSLDYNTIF 365
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
1-510 |
0e+00 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 1082.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 1 MSNIDIEGILKELPNDG-RTPKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILA 79
Cdd:PLN02461 1 MANIDIEGILKGLPADGlRRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 80 AVMLDTKGPEIRTGFLKDGNPIQLKEGQEITITTDYDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNA 159
Cdd:PLN02461 81 AVMLDTKGPEIRTGFLKDGKPVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 160 GTVICRCENTAMLGERKNVNLPGVVVDLPTLTDKDVEDILKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMS 239
Cdd:PLN02461 161 GTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDILQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLIS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 240 KVENQEGVLNFDEILRETDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 319
Cdd:PLN02461 241 KVENQEGLDNFDDILAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 320 NAVLDGTDCVMLSGESAAGAYPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMSTLESLASSAVRTANKAKAKLII 399
Cdd:PLN02461 321 NAVLDGTDCVMLSGETAAGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSPLESLASSAVRTANKVKASLIV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 400 VLTRGGTTAKLVAKYRPAVPILSVVVPVFTSDTFNWSCSDESPARHSLIYRGLIPVLGEGSAKATDSESTEEIIESALKS 479
Cdd:PLN02461 401 VLTRGGTTARLVAKYRPAVPILSVVVPEITTDSFDWSCSDEAPARHSLIYRGLIPVLAEGSAKATDSESTEEILEAAIEH 480
|
490 500 510
....*....|....*....|....*....|.
gi 15242863 480 ATEKGLCNHGDAVVALHRIGAASVIKICVVK 510
Cdd:PLN02461 481 AKKKGLCKPGDSVVALHRIGGASVIKILTVK 511
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
20-509 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 726.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 20 PKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGN 99
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 100 PIQLKEGQEITITTDY-DIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNAgTVICRCENTAMLGERKNV 178
Cdd:cd00288 82 DISLKAGDKFLVTTDPaAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDK-TLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 179 NLPGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMSKVENQEGVLNFDEILRETD 258
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADL-RFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 259 AFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 338
Cdd:cd00288 240 GIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 339 AYPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAV 418
Cdd:cd00288 320 KYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 419 PILSVvvpvftsdTFNwscsdESPARHSLIYRGLIPVLGEgSAKATDSESTEEIIESALKSATEKGLCNHGDAVVALHRI 498
Cdd:cd00288 400 PIIAV--------TRN-----EQTARQLHLYRGVYPVLFE-EPKPGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGW 465
|
490
....*....|....*
gi 15242863 499 ----GAASVIKICVV 509
Cdd:cd00288 466 pvgsGSTNTMRILTV 480
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
21-509 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 638.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 21 KTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:COG0469 4 RTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG-P 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 101 IQLKEGQEITITTDyDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNAgtVICRCENTAMLGERKNVNL 180
Cdd:COG0469 83 VELKKGDTFTLTTD-DVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDE--VVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 181 PGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMSKVENQEGVLNFDEILRETDAF 260
Cdd:COG0469 160 PGVGLSLPALTEKDREDL-KFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 261 MVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAY 340
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 341 PEIAVKTMAKICIEAESSLDYNTIFKEmiRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAVPI 420
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRRILDR--LRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPI 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 421 LSVvvpvftsdtfnwsCSDESPARHSLIYRGLIPVLGEgsakatDSESTEEIIESALKSATEKGLCNHGDAVV-----AL 495
Cdd:COG0469 397 LAL-------------TPNERTARRLALVWGVYPVLVD------DVESTDEMIEEAVEALLEEGLVKPGDLVVitagvPV 457
|
490
....*....|....
gi 15242863 496 HRIGAASVIKICVV 509
Cdd:COG0469 458 GVPGTTNTLKVHRV 471
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-499 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 571.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 2 SNIDIEGILKELP-NDGRTPKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAM-QNTGILA 79
Cdd:PTZ00066 19 TNISLDKILEPISdNDLRQKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAkARPNANL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 80 AVMLDTKGPEIRTGFLKDGNPIQLKEGQEITITTDYDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNa 159
Cdd:PTZ00066 99 GILLDTKGPEIRTGFLKNHKPITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDD- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 160 gTVICRCENTAMLGERKNVNLPGVVVDLPTLTDKDVEDILKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMS 239
Cdd:PTZ00066 178 -YIITKVLNNATIGERKNMNLPGVKVELPVIGEKDKNDILNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIP 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 240 KVENQEGVLNFDEILRETDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 319
Cdd:PTZ00066 257 KIENIEGLINFDEILAESDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVA 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 320 NAVLDGTDCVMLSGESAAGAYPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMSTLESLASSAVRTANKAKAKLII 399
Cdd:PTZ00066 337 NAVLDGTDCVMLSGETANGKFPVEAVNIMAKICFEAETCIDYRVLYHAIHLAVPTPVSVQEAVARSAVETAEDINAKLII 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 400 VLTRGGTTAKLVAKYRPAVPILSVvvpvftsdtfnwsCSDESPARHSLIYRGLIpvlgegSAKATDSESTEEIIESALKS 479
Cdd:PTZ00066 417 ALTETGNTARLISKYRPSCTILAL-------------SASPSVVKSLSVARGVT------TYVVNSFQGTDVVIRNAIAL 477
|
490 500
....*....|....*....|
gi 15242863 480 ATEKGLCNHGDAVVALHRIG 499
Cdd:PTZ00066 478 AKERGLVESGDSAIAVHGVK 497
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
21-503 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 564.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 21 KTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:TIGR01064 2 RTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGG-E 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 101 IQLKEGQEITITTDYDIK-GDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNagTVICRCENTAMLGERKNVN 179
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKGeGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGD--KVICEVLNGGTLKSKKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 180 LPGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSH-SKSIMLMSKVENQEGVLNFDEILRETD 258
Cdd:TIGR01064 159 LPGADVDLPALSEKDKKDL-KFGVEQGVDMVAASFVRTAEDVLEVREVLGEKgAKDVKIIAKIENQEGVDNIDEIAEASD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 259 AFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 338
Cdd:TIGR01064 238 GIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 339 AYPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAV 418
Cdd:TIGR01064 318 KYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 419 PILSVVVpvftsdtfnwscsDESPARHSLIYRGLIPVLGEGSAkatdsESTEEIIESALKSATEKGLCNHGDAVVALHRI 498
Cdd:TIGR01064 398 PIIAVTP-------------NERVARQLALYWGVFPFLVDEEP-----SDTDARVNKALELLKEKGIVKKGDLVVVIQGG 459
|
....*
gi 15242863 499 GAASV 503
Cdd:TIGR01064 460 PIGGE 464
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
20-365 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 562.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 20 PKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDG- 98
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 99 NPIQLKEGQEITITTDYDIKG--DEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPnAGTVICRCENTAMLGERK 176
Cdd:pfam00224 82 KDIELKAGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDD-DKTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 177 NVNLPGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMSKVENQEGVLNFDEILRE 256
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADL-RFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 257 TDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESA 336
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*....
gi 15242863 337 AGAYPEIAVKTMAKICIEAESSLDYNTIF 365
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
21-493 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 527.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 21 KTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:PRK05826 5 RTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG-K 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 101 IQLKEGQEITITTDYDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNagTVICRCENTAMLGERKNVNL 180
Cdd:PRK05826 84 ITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGD--EVETEVKNGGPLSNNKGINI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 181 PGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSH-SKSIMLMSKVENQEGVLNFDEILRETDA 259
Cdd:PRK05826 162 PGGGLSLPALTEKDKADI-KFAAEQGVDYIAVSFVRSAEDVEEARRLLREAgCPHAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 260 FMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGA 339
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 340 YPEIAVKTMAKICIEAESSLDYNTIFKEMIRATplpMSTLESLASSAVRTANKAK-AKLIIVLTRGGTTAKLVAKYRPAV 418
Cdd:PRK05826 321 YPVEAVEAMARICKGAEKEFSINLSKHRLDRQF---DRIDEAIAMSAMYAANHLKgVKAIVALTESGRTARLISRFRPGA 397
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15242863 419 PILSVvvpvftsdtfnwsCSDESPARHSLIYRGLIPVLGEGSAkatdseSTEEIIESALKSATEKGLCNHGDAVV 493
Cdd:PRK05826 398 PIFAV-------------TRDEKTQRRLALYRGVYPVLFDSAA------DTDDAAEEALRLLLEKGLVESGDLVV 453
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
22-506 |
0e+00 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 522.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 22 TKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTgFLKDGNPI 101
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQV-INKTEKPI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 102 QLKEGQEITITTDYDIKGDEKTISMSYKKLPVDVKPGNTILCAD--------GSISLAVVscDPNAGTVICRCENTAML- 172
Cdd:PLN02765 109 SLKAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVGQylftgsetTSVWLEVD--EVKGDDVVCTVKNSATLa 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 173 GERKNVNLPGVVVDLPTLTDKDVEDILKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHS-KSIMLMSKVENQEGVLNFD 251
Cdd:PLN02765 187 GSLFTLHVSQVRIDLPTLSEKDKEVISTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlSQTQIFAKIENVEGLTHFD 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 252 EILRETDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTaTQMLESMIKSPRPTRAEATDVANAVLDGTDCVML 331
Cdd:PLN02765 267 EILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILL 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 332 SGESAAGAYPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLV 411
Cdd:PLN02765 346 GAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKKTVKYVGEPMSHLESIASSAVRAAIKVKASVIIVFTSSGRAARLI 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 412 AKYRPAVPILSVVVPVFTSDTFNWSCSDESPARHSLIYRGLIPVLGEGSAKATDSESTEE-IIESALKSATEKGLCNHGD 490
Cdd:PLN02765 426 AKYRPTMPVLSVVIPRLKTNQLKWSFTGAFQARQCLIVRGLFPMLADPRHSAESTSATNEsVLKVALDHGKAAGVIKSHD 505
|
490
....*....|....*.
gi 15242863 491 AVVALHRIGAASVIKI 506
Cdd:PLN02765 506 RVVVCQKVGDSSVVKI 521
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
21-493 |
4.64e-179 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 511.14 E-value: 4.64e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 21 KTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGNP 100
Cdd:PRK09206 3 KTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGGND 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 101 IQLKEGQEITITTDYDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCdpNAGTVICRCENTAMLGERKNVNL 180
Cdd:PRK09206 83 VSLKAGQTFTFTTDKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAI--TGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 181 PGVVVDLPTLTDKDVEDiLKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHS-KSIMLMSKVENQEGVLNFDEILRETDA 259
Cdd:PRK09206 161 PGVSIALPALAEKDKQD-LIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGgENIQIISKIENQEGLNNFDEILEASDG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 260 FMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGA 339
Cdd:PRK09206 240 IMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 340 YPEIAVKTMAKICIEAE----SSLDYNTIFKEMiRATplpmstlESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYR 415
Cdd:PRK09206 320 YPLEAVSIMATICERTDrvmnSRLESNNDNRKL-RIT-------EAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYF 391
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15242863 416 PAVPILSVVvpvftsdtfnwscSDESPARHSLIYRGLIPVLgegsAKATDseSTEEIIESALKSATEKGLCNHGDAVV 493
Cdd:PRK09206 392 PDATILALT-------------TNEKTARQLVLSKGVVPQL----VKEIA--STDDFYRLGKELALQSGLAQKGDVVV 450
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
21-493 |
3.43e-158 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 462.47 E-value: 3.43e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 21 KTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:PRK06354 9 RTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDG-P 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 101 IQLKEGQEITITTDyDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNAGTVICRCENTAMLGERKNVNL 180
Cdd:PRK06354 88 IELKTGDEFILTSR-EVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKADGELHCKVLVGGVLSNKKGVNF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 181 PGVVVDLPTLTDKDVEDILkWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHS-KSIMLMSKVENQEGVLNFDEILRETDA 259
Cdd:PRK06354 167 PGVSLSLPAITEKDREDLI-FGLEQGVDWIALSFVRNPSDVLEIRELIEEHNgKHIPIIAKIEKQEAIDNIDAILELCDG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 260 FMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGA 339
Cdd:PRK06354 246 LMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGD 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 340 YPEIAVKTMAKICIEAESSLDYNTIFKEMiratPLPMSTLESLASSAV-RTANKAKAKLIIVLTRGGTTAKLVAKYRPAV 418
Cdd:PRK06354 326 YPVEAVQTMATIAVRIEKDLPYRDILSKR----PEFTTTITNAISQAVsHIALQLDAAAIVTLTKSGATARNVSKYRPKT 401
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15242863 419 PILSVVvpvftsdtfnwscSDESPARH-SLIYrGLIPVLGEgsakatDSESTEEIIESALKSATEKGLCNHGDAVV 493
Cdd:PRK06354 402 PILAVT-------------PNESVARRlQLVW-GVTPLLVL------DAPSTDETFDAAINVAQESGLLKQGDLVV 457
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
46-496 |
6.78e-144 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 421.00 E-value: 6.78e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 46 MNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDGNPIqLKEGQEITITTD--YDIKGDEKT 123
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAV-MERGATCYVTTDpaFADKGTKDK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 124 ISMSYKKLPVDVKPGNTILCADGSISLAVVSCDpNAGTVICRCENTAMLGERKNVNLPGVVVDLPTLTDKDVEDiLKWGV 203
Cdd:PTZ00300 80 FYIDYQNLSKVVRPGGYIYIDDGILILHVQSHE-DEQTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCAD-LQFGV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 204 PNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMSKVENQEGVLNFDEILRETDAFMVARGDLGMEIPIEKIFLAQKMM 283
Cdd:PTZ00300 158 EQGVDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKIL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 284 IYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKTMAKICIEAESSLDYNT 363
Cdd:PTZ00300 238 ISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 364 IFKEMIRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAVPILSVVVPVFTSDTFNwscsdespa 443
Cdd:PTZ00300 318 FFNSIKKLQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLN--------- 388
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 15242863 444 rhslIYRGLIPVLGEGSAKATDsESTEEIIESALKSATEKGLCNHGDAVVALH 496
Cdd:PTZ00300 389 ----ITQGVESVFFDAERLGHD-EGKEQRVAMGVGFAKSKGYVQSGDLMVVVH 436
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
18-493 |
2.51e-142 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 417.79 E-value: 2.51e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 18 RTPKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKD 97
Cdd:PRK06247 3 RNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFAD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 98 GnPIQLKEGQEITITTDyDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNAgtVICRCENTAMLGERKN 177
Cdd:PRK06247 83 G-KVQLANGQTFRLDVD-DAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDD--VVCRVVEGGPVSDRKG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 178 VNLPGVVVDLPTLTDKDVEDiLKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHsksIMLMSKVENQEGVLNFDEILRET 257
Cdd:PRK06247 159 VSLPGTVLSVSALTEKDRAD-LEFALELGVDWVALSFVQRPEDVEEVRKIIGGR---VPVMAKIEKPQAIDRLEAIVEAS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 258 DAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAA 337
Cdd:PRK06247 235 DAIMVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETAS 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 338 GAYPEIAVKTMAKICIEAESSLDYNTIfkemIRAT-PLPMSTLESLASSAVR-TANKAKAKLIIVLTRGGTTAKLVAKYR 415
Cdd:PRK06247 315 GKYPVEAVRTMARIIRQVERDPTYPPL----IHAQrPQPEATKRDAISYAARdIAERLDLAALVAYTSSGDTALRAARER 390
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15242863 416 PAVPILsvvvpVFTSDTfnwscsdESPARHSLIYrGLIPVLGEgsakatDSESTEEIIESALKSATEKGLCNHGDAVV 493
Cdd:PRK06247 391 PPLPIL-----ALTPNP-------ETARRLALTW-GVHCVVVD------DARDTDDMVRRADRIALAEGFYKRGDRVV 449
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
21-492 |
3.19e-106 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 328.81 E-value: 3.19e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 21 KTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRT-AMQNTGILAAVMLDTKGPEIRTGFLKDgn 99
Cdd:PLN02623 111 KTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEyNAQSKDNVIAIMLDTKGPEVRSGDLPQ-- 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 100 PIQLKEGQEITITTDYDIkGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVScdPNAGTVICRCENTAMLGERKNVN 179
Cdd:PLN02623 189 PIMLEEGQEFTFTIKRGV-STEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKS--KTSDSVKCEVVDGGELKSRRHLN 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 180 LPGVVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSKSIMLMSKVENQEGVLNFDEILRETDA 259
Cdd:PLN02623 266 VRGKSATLPSITEKDWEDI-KFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIITASDG 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 260 FMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGA 339
Cdd:PLN02623 345 AMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGK 424
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 340 YPEIAVKTMAKICIEAESSLDYNTIFKEMIRATPLPMStlESLASSAVRTANKAKAKlIIVLTRGGTTAKLVAKYRPAVP 419
Cdd:PLN02623 425 FPLKAVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMS--EMFAFHATMMANTLGTS-IIVFTRTGFMAILLSHYRPSGT 501
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242863 420 ILSvvvpvFTsdtfnwscSDESPARHSLIYRGLIPVLGEGSAKAtdsestEEIIESALKSATEKGLCNHGDAV 492
Cdd:PLN02623 502 IFA-----FT--------NEKRIQQRLALYQGVCPIYMQFSDDA------EETFARALSLLLNKGMVKEGEEV 555
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
25-356 |
3.50e-87 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 272.20 E-value: 3.50e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 25 VCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAavmlDTKGPEIRTGFLKdGNPIQLK 104
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSIKILG----DVQGPKIRLGEIK-GEQITLQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 105 EGQEITITTDyDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAV--VSCDpnagTVICRCENTAMLGERKNVNLPG 182
Cdd:PRK06739 81 AGDSFILHTQ-PVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVekVSTD----KIETKVKTGGNISSHKGVNLPG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 183 VVVDLPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHSK-SIMLMSKVENQEGVLNFDEILRETDAFM 261
Cdd:PRK06739 156 AIVRLPAITEKDKKDI-QFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKEtSPNLIAKIETMEAIENFQDICKEADGIM 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 262 VARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYP 341
Cdd:PRK06739 235 IARGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHP 314
|
330
....*....|....*
gi 15242863 342 EIAVKTMAKICIEAE 356
Cdd:PRK06739 315 IESVSTLRLVSEFAE 329
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
19-510 |
1.11e-86 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 275.86 E-value: 1.11e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 19 TPKTKIVCTLGPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKDG 98
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDLGGA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 99 NPIQLKEGQEITITT-DYDIKGDEKTISMSYKKLPVDVKPGNTILCADGSISLAVVscDPNAGTVICRCENTAMLGERKN 177
Cdd:PLN02762 104 SSAKAEDGEEWTFTVrKFDGSRPEFTIQVNYDGFAEDVKVGDELVVDGGMVRFEVI--EKIGPDVKCKCTDPGLLLPRAN 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 178 VNL--PGVVVD-----LPTLTDKDVEDIlKWGVPNNIDMIALSFVRKGSDLVNVRKVLGSHS--KSIMLMSKVENQEGVL 248
Cdd:PLN02762 182 LTFwrDGSLVRernamLPTISSKDWLDI-DFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSrdSDIGVIAKIESLDSLK 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 249 NFDEILRETDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDC 328
Cdd:PLN02762 261 NLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRADA 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 329 VMLSGESAAGAYPEIAVKTMAKICIEAESSLDYNTIFKEMIR---ATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGG 405
Cdd:PLN02762 341 LMLSGESAMGLYPEKALSVLRSVSLRMELWSREEKRHEALELpqlSSSLSDRISEEICNSAAKMANNLGVDAIFVYTKHG 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 406 TTAKLVAKYRPAVPILSvvvpvFTSDTfnwscsdesPARHSL-IYRGLIPVLGEGSakaTDSESTEEIIESALKSateKG 484
Cdd:PLN02762 421 HMASLLSRNRPDCPIFA-----FTDTT---------SVRRRLnLQWGLIPFRLDFS---DDMESNLNKTFSLLKA---RG 480
|
490 500
....*....|....*....|....*.
gi 15242863 485 LCNHGDAVVALHRIGAASVIKICVVK 510
Cdd:PLN02762 481 MIKSGDLVIAVSDLTPSSMLQSIQVR 506
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
286-493 |
5.41e-47 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 165.84 E-value: 5.41e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 286 KCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKTMAKICIEAESSLDYNTIF 365
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 366 KEmiRATPLPMSTLESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAVPILSVVvpvftsdtfnwscSDESPARH 445
Cdd:COG3848 81 VP--RAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVT-------------PSERVARQ 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 15242863 446 SLIYRGLIPVLGEgsakatDSESTEEIIESALKSATEKGLCNHGDAVV 493
Cdd:COG3848 146 LSLVWGVYPLLVE------ESASTDEMFAVAVALALEAGLVKDGDLVV 187
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
19-331 |
1.04e-42 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 158.64 E-value: 1.04e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 19 TPKTKIVCTL-GPASRSVTMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIRTGFLKD 97
Cdd:PRK08187 132 ARRTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVAG 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 98 GNPIQ-LKEGQEITITTDYDIKGDEKT---ISMSYKKLPVDVKPGNTILCADGSISLAVVSCDPNAgtVICRCENTAMLG 173
Cdd:PRK08187 212 PLGKTrLYTGDRLALVAQGPPRRIDEEhfqVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGG--ALLEVTHARPKG 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 174 ER----KNVNLPGVVVDLPTLTDKDVEDiLKWgVPNNIDMIALSFVRKGSDL------VNVRKVLGSHSKSIMLmsKVEN 243
Cdd:PRK08187 290 LKlkpeKGLNFPDTALDLPALTEKDRAD-LDF-VARHADLVGYSFVQSPGDVealqaaLAARRPDDWRKLGLVL--KIET 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 244 QEGVLNFDEIL-----RETDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDV 318
Cdd:PRK08187 366 PRAVANLPELIvqaagRQPFGVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDA 445
|
330
....*....|...
gi 15242863 319 ANAvlDGTDCVML 331
Cdd:PRK08187 446 AMA--ARAECVML 456
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
28-351 |
1.17e-34 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 137.39 E-value: 1.17e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 28 LGPASRS------VTM----------IEKLLKAGMNVARFNFSHGSHEYHQETLDNLRTAMQNTGILAAVMLDTKGPEIR 91
Cdd:PRK14725 132 LGPPPSGrptrimVTLpteaaddpdlVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLR 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 92 TGFLKDG------------------------------------------------------------------------- 98
Cdd:PRK14725 212 TGPIAPGprviklrptrdalgrvltparlwltasespppspppgpvglpvdpewlarlepgdelrftdargkkrkltvte 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 99 ---------------------------------------NPIQLKEGQEITITTDyDIKGD-------EKTISMSYKKLP 132
Cdd:PRK14725 292 vddegvlaegsqtaylangtllrlgrhdstrvgglppveQKLRLKVGDRLVLTRD-DAPGDpaqgdapPARISCTLPEAF 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 133 VDVKPGNTILCADGSISLAVVSCDPNAGTV-ICRC-ENTAMLGERKNVNLPGVVVDLPTLTDKDVED---ILKWGvpnni 207
Cdd:PRK14725 371 RAARVGERVWFDDGKIGAVVVKVEADEVELrITHArPGGSKLKAGKGINLPDSHLPLPALTDKDLEDlafVAKHA----- 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 208 DMIALSFVRKGSDlvnVRKVLGSHSK----SIMLMSKVENQEGVLNFDEILRETDAF-----MVARGDLGMEIPIEKIFL 278
Cdd:PRK14725 446 DIVALSFVRSPED---VRLLLDALEKlgadDLGVVLKIETRRAFENLPRILLEAMRHprfgvMIARGDLAVEVGFERLAE 522
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15242863 279 AQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLdgTDCVMLSgesaAGAYPEIAVKTMAKI 351
Cdd:PRK14725 523 VQEEILWLCEAAHVPVIWATQVLESLAKKGLPSRAEITDAAMALR--AECVMLN----KGPHIVEAVRVLDDI 589
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
380-506 |
1.39e-25 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 101.02 E-value: 1.39e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15242863 380 ESLASSAVRTANKAKAKLIIVLTRGGTTAKLVAKYRPAVPILSVvvpvftsdtfnwsCSDESPARHSLIYRGLIPVLGEg 459
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAV-------------TPNELTARQLALYWGVYPVLFD- 66
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 15242863 460 sakatDSESTEEIIESALKSATEKGLCNHGDAVVALHRI-----GAASVIKI 506
Cdd:pfam02887 67 -----EAETTDEMLRRAVKVAKEAGLVKKGDLVVITAGVpfgvsGTTNTLKV 113
|
|
| |
