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Conserved domains on  [gi|15237300|ref|NP_200103|]
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timeless family protein [Arabidopsis thaliana]

Protein Classification

timeless family protein( domain architecture ID 10521730)

timeless family protein such as fungal topoisomerase 1-associated factor 1 that forms a fork protection complex (FPC) with CSM3, which is required for chromosome segregation during meiosis and DNA damage repair

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TIMELESS pfam04821
Timeless protein; The timeless gene in Drosophila melanogaster and its homologs in a number of ...
38-297 1.37e-66

Timeless protein; The timeless gene in Drosophila melanogaster and its homologs in a number of other insects and mammals (including human) are involved in circadian rhythm control. This family includes a related proteins from a number of fungal species.


:

Pssm-ID: 461444  Cd Length: 273  Bit Score: 225.53  E-value: 1.37e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300     38 GYSKSEYCLDNLKDLLRFLRRDD-PESREVFKQVCAWNIVSKDLIPIIEHYQ--DEHNLVLNAVKVLVFLTMPIEP---- 110
Cdd:pfam04821    1 VYVLGDDCLACLKDLKRWLRRDDdDNRRDVARALAEANLVQNDLLPILLQWTegDGKKIALACLELLVNLTWPLELltee 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300    111 ----SSDDIPQQLEYLWGLKSAITFSNIVAVIVSLLEAPLeNLELDVFNEEDWKLVQLVLTLFRNLLAIHDVSPIQKAGE 186
Cdd:pfam04821   81 etvnQRRHYPQLQKAQLGYKRAILDYKVLKAVVRLLLPPL-AKPREDRTERDNGIIELVLYLIRNILAIPPPPENEKRSS 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300    187 STCYFLSLRDQFLEVLSRENVMDIVLVITQTIEGFNsLLRHDNLLLLEIYHYILLGQDMELVAKAP----EKLDQGKQAS 262
Cdd:pfam04821  160 DGAEDDILHSAVIWAFHEQGVLDLLLTLASSIGSDF-EFQQWNVLLLEIIYLLFKGQDPESLASASspdeERSTSEKKRD 238
                          250       260       270
                   ....*....|....*....|....*....|....*
gi 15237300    263 VDSLKTLMKEEEvKRKLARLNNMNQRHSQFGGTFT 297
Cdd:pfam04821  239 GDELSDLLEKEK-KMKRAQARNASSRHSRFGGTLS 272
Csa3 super family cl34607
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
846-987 2.10e-03

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


The actual alignment was detected with superfamily member COG3415:

Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 41.76  E-value: 2.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300  846 RRLVLDGDMDIKIKDLYDRYKDDKNCSRLIAENLVpDGGISAAQVTNKLkQLGLET----RKRLRRGGTDHLdatslaQP 921
Cdd:COG3415    1 SRLTLTEEERRDLEKLLRKTKDAREARRLRAVLLL-AEGLSVREIAERL-GVSRSTvyrwLKRYREGGLAGL------KD 72
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237300  922 SNTRKRVSSFSKEQETLIKELYKKFK-DEKRCCYL--IASELGSEN--TYTTAQVSRKLKQLGLRLPRGKK 987
Cdd:COG3415   73 RPRGGRPSKLSDEQRERLLELLREKSpDQGSRWTLaeLAELLEEEFgvEVSPSTVRRLLKRLGLSYKKPRP 143
 
Name Accession Description Interval E-value
TIMELESS pfam04821
Timeless protein; The timeless gene in Drosophila melanogaster and its homologs in a number of ...
38-297 1.37e-66

Timeless protein; The timeless gene in Drosophila melanogaster and its homologs in a number of other insects and mammals (including human) are involved in circadian rhythm control. This family includes a related proteins from a number of fungal species.


Pssm-ID: 461444  Cd Length: 273  Bit Score: 225.53  E-value: 1.37e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300     38 GYSKSEYCLDNLKDLLRFLRRDD-PESREVFKQVCAWNIVSKDLIPIIEHYQ--DEHNLVLNAVKVLVFLTMPIEP---- 110
Cdd:pfam04821    1 VYVLGDDCLACLKDLKRWLRRDDdDNRRDVARALAEANLVQNDLLPILLQWTegDGKKIALACLELLVNLTWPLELltee 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300    111 ----SSDDIPQQLEYLWGLKSAITFSNIVAVIVSLLEAPLeNLELDVFNEEDWKLVQLVLTLFRNLLAIHDVSPIQKAGE 186
Cdd:pfam04821   81 etvnQRRHYPQLQKAQLGYKRAILDYKVLKAVVRLLLPPL-AKPREDRTERDNGIIELVLYLIRNILAIPPPPENEKRSS 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300    187 STCYFLSLRDQFLEVLSRENVMDIVLVITQTIEGFNsLLRHDNLLLLEIYHYILLGQDMELVAKAP----EKLDQGKQAS 262
Cdd:pfam04821  160 DGAEDDILHSAVIWAFHEQGVLDLLLTLASSIGSDF-EFQQWNVLLLEIIYLLFKGQDPESLASASspdeERSTSEKKRD 238
                          250       260       270
                   ....*....|....*....|....*....|....*
gi 15237300    263 VDSLKTLMKEEEvKRKLARLNNMNQRHSQFGGTFT 297
Cdd:pfam04821  239 GDELSDLLEKEK-KMKRAQARNASSRHSRFGGTLS 272
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
846-987 2.10e-03

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 41.76  E-value: 2.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300  846 RRLVLDGDMDIKIKDLYDRYKDDKNCSRLIAENLVpDGGISAAQVTNKLkQLGLET----RKRLRRGGTDHLdatslaQP 921
Cdd:COG3415    1 SRLTLTEEERRDLEKLLRKTKDAREARRLRAVLLL-AEGLSVREIAERL-GVSRSTvyrwLKRYREGGLAGL------KD 72
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237300  922 SNTRKRVSSFSKEQETLIKELYKKFK-DEKRCCYL--IASELGSEN--TYTTAQVSRKLKQLGLRLPRGKK 987
Cdd:COG3415   73 RPRGGRPSKLSDEQRERLLELLREKSpDQGSRWTLaeLAELLEEEFgvEVSPSTVRRLLKRLGLSYKKPRP 143
 
Name Accession Description Interval E-value
TIMELESS pfam04821
Timeless protein; The timeless gene in Drosophila melanogaster and its homologs in a number of ...
38-297 1.37e-66

Timeless protein; The timeless gene in Drosophila melanogaster and its homologs in a number of other insects and mammals (including human) are involved in circadian rhythm control. This family includes a related proteins from a number of fungal species.


Pssm-ID: 461444  Cd Length: 273  Bit Score: 225.53  E-value: 1.37e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300     38 GYSKSEYCLDNLKDLLRFLRRDD-PESREVFKQVCAWNIVSKDLIPIIEHYQ--DEHNLVLNAVKVLVFLTMPIEP---- 110
Cdd:pfam04821    1 VYVLGDDCLACLKDLKRWLRRDDdDNRRDVARALAEANLVQNDLLPILLQWTegDGKKIALACLELLVNLTWPLELltee 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300    111 ----SSDDIPQQLEYLWGLKSAITFSNIVAVIVSLLEAPLeNLELDVFNEEDWKLVQLVLTLFRNLLAIHDVSPIQKAGE 186
Cdd:pfam04821   81 etvnQRRHYPQLQKAQLGYKRAILDYKVLKAVVRLLLPPL-AKPREDRTERDNGIIELVLYLIRNILAIPPPPENEKRSS 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300    187 STCYFLSLRDQFLEVLSRENVMDIVLVITQTIEGFNsLLRHDNLLLLEIYHYILLGQDMELVAKAP----EKLDQGKQAS 262
Cdd:pfam04821  160 DGAEDDILHSAVIWAFHEQGVLDLLLTLASSIGSDF-EFQQWNVLLLEIIYLLFKGQDPESLASASspdeERSTSEKKRD 238
                          250       260       270
                   ....*....|....*....|....*....|....*
gi 15237300    263 VDSLKTLMKEEEvKRKLARLNNMNQRHSQFGGTFT 297
Cdd:pfam04821  239 GDELSDLLEKEK-KMKRAQARNASSRHSRFGGTLS 272
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
846-987 2.10e-03

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 41.76  E-value: 2.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237300  846 RRLVLDGDMDIKIKDLYDRYKDDKNCSRLIAENLVpDGGISAAQVTNKLkQLGLET----RKRLRRGGTDHLdatslaQP 921
Cdd:COG3415    1 SRLTLTEEERRDLEKLLRKTKDAREARRLRAVLLL-AEGLSVREIAERL-GVSRSTvyrwLKRYREGGLAGL------KD 72
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15237300  922 SNTRKRVSSFSKEQETLIKELYKKFK-DEKRCCYL--IASELGSEN--TYTTAQVSRKLKQLGLRLPRGKK 987
Cdd:COG3415   73 RPRGGRPSKLSDEQRERLLELLREKSpDQGSRWTLaeLAELLEEEFgvEVSPSTVRRLLKRLGLSYKKPRP 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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