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Conserved domains on  [gi|15237948|ref|NP_197234|]
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homeodomain GLABROUS 9 [Arabidopsis thaliana]

Protein Classification

homeobox-leucine zipper protein( domain architecture ID 11078707)

homeobox-leucine zipper protein containing a C-terminal lipid-binding START domain and belonging to the HD-ZIP homeobox family of transcription factors, similar to Arabidopsis thaliana HD-ZIP protein HDG7 that binds to the DNA sequence 5'-GCATTAAATGC-3'

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
START_ArGLABRA2_like cd08875
C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related ...
239-460 5.31e-80

C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins; This subfamily includes the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of the Arabidopsis homeobox protein GLABRA 2 and related proteins. The START domain family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. Most proteins in this subgroup contain an N-terminal homeobox DNA-binding domain, some contain a leucine zipper. ArGLABRA2 plays a role in the differentiation of hairless epidermal cells of the Arabidopsis root. It acts in a cell-position-dependent manner to suppress root hair formation in those cells.


:

Pssm-ID: 176884  Cd Length: 229  Bit Score: 254.50  E-value: 5.31e-80
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948 239 MLEAAEKAVSEVLSLIQMDDTMWKKSSIDDRLVIDPGLYEKYFTKTNTNGRP----ESSKDVVVVQMDAGNLIDIFLTAE 314
Cdd:cd08875   4 LLELAEEAMDELLKLAQGGEPLWIKSPGMKPEILNPDEYERMFPRHGGSKPGgfttEASRACGLVMMNAIKLVEILMDVN 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948 315 KWARLFPTIVNEAKTIHVLDS-VDHRGKTFSRVIYEQLHILSPLVPPREFMILRTCQQIEDNVWMIADVSC-HLPNIEFD 392
Cdd:cd08875  84 KWSELFPGIVSKAKTLQVISTgNGGNRNGTLQLMYAELQVPSPLVPTREFYFLRYCKQLEDGLWAVVDVSIdGVQTAPPP 163
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237948 393 LSFPICTKRPSGVLIQALPHGFSKVTWIEHVVVNDNRVrpHKLYRDLLYGGFGYGARRWTVTLERTCE 460
Cdd:cd08875 164 ASFVRCRRLPSGCLIQDMPNGYSKVTWVEHVEVDEKPV--HLLYRYLVSSGLAFGATRWVATLQRQCE 229
Homeodomain pfam00046
Homeodomain;
27-82 9.64e-19

Homeodomain;


:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 80.24  E-value: 9.64e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15237948    27 KKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAK 82
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
 
Name Accession Description Interval E-value
START_ArGLABRA2_like cd08875
C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related ...
239-460 5.31e-80

C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins; This subfamily includes the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of the Arabidopsis homeobox protein GLABRA 2 and related proteins. The START domain family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. Most proteins in this subgroup contain an N-terminal homeobox DNA-binding domain, some contain a leucine zipper. ArGLABRA2 plays a role in the differentiation of hairless epidermal cells of the Arabidopsis root. It acts in a cell-position-dependent manner to suppress root hair formation in those cells.


Pssm-ID: 176884  Cd Length: 229  Bit Score: 254.50  E-value: 5.31e-80
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948 239 MLEAAEKAVSEVLSLIQMDDTMWKKSSIDDRLVIDPGLYEKYFTKTNTNGRP----ESSKDVVVVQMDAGNLIDIFLTAE 314
Cdd:cd08875   4 LLELAEEAMDELLKLAQGGEPLWIKSPGMKPEILNPDEYERMFPRHGGSKPGgfttEASRACGLVMMNAIKLVEILMDVN 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948 315 KWARLFPTIVNEAKTIHVLDS-VDHRGKTFSRVIYEQLHILSPLVPPREFMILRTCQQIEDNVWMIADVSC-HLPNIEFD 392
Cdd:cd08875  84 KWSELFPGIVSKAKTLQVISTgNGGNRNGTLQLMYAELQVPSPLVPTREFYFLRYCKQLEDGLWAVVDVSIdGVQTAPPP 163
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237948 393 LSFPICTKRPSGVLIQALPHGFSKVTWIEHVVVNDNRVrpHKLYRDLLYGGFGYGARRWTVTLERTCE 460
Cdd:cd08875 164 ASFVRCRRLPSGCLIQDMPNGYSKVTWVEHVEVDEKPV--HLLYRYLVSSGLAFGATRWVATLQRQCE 229
START pfam01852
START domain;
241-461 3.25e-22

START domain;


Pssm-ID: 426476  Cd Length: 205  Bit Score: 95.16  E-value: 3.25e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948   241 EAAEKAVSEVLSLIQMDDTMWKKSSiddrlvidPGLYEKYFTKTNTNGRPESSKDVVVVQMDAGNLI-DIFLTAEKWArL 319
Cdd:pfam01852   1 ELAEEAAQELLKLALSDEPGWVLLS--------SNENGDVVLQIVEPDHGEASRASGVVPMVAALLVaELLKDMEYRA-Q 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948   320 FPTIVNEAKTIHVLDSvdhrgKTFSRVIYEQLHILSPlVPPREFMILRTCQQIEDNVWMIADVSCHLPNIEFDLSFPICT 399
Cdd:pfam01852  72 WDKDVRSAETLEVISS-----GGDLQYYVAALVAPSP-LSPRDFVFLRYWRRLGGGVYVIVDRSVTHPQFPPSSGYVRAE 145
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15237948   400 KRPSGVLIQALPHGFSKVTWIEHVVVNDNrvRPHKLYRDLLYGGFGYGARRWTVTLERTCER 461
Cdd:pfam01852 146 RLPSGYLIQPCGNGPSKVTWVSHADLKGW--LPSWLLRSLYKSGMPEGAKTWVATLQRLCEK 205
START smart00234
in StAR and phosphatidylcholine transfer protein; putative lipid-binding domain in StAR and ...
243-461 1.47e-19

in StAR and phosphatidylcholine transfer protein; putative lipid-binding domain in StAR and phosphatidylcholine transfer protein


Pssm-ID: 214575  Cd Length: 205  Bit Score: 87.49  E-value: 1.47e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948    243 AEKAVSEVLSLIQMDDTMWKKSSiddrlVIDPGlyEKYFTKTNTNGRP-ESSKDVVVVQMDAGNLI-DIFLTAEKWArLF 320
Cdd:smart00234   2 AEEAAAELLKMAAASEEGWVLSS-----ENENG--DEVRSIFSPGRKPgEAFRLVGVVPMVCADLVeELMDDLEYRP-EW 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948    321 PTIVNEAKTIHVLDSVDhrgktfsrVIYeqlHILSP----LVPPREFMILRTCQQIEDNVWMIADVSCHLPNIEFDLSFP 396
Cdd:smart00234  74 DKNVAKAETLEVIDNGT--------VIY---HYVSKfaagPVSPRDFVFVRYWREDEDGSYAVVDVSVTHPTSPPESGYV 142
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15237948    397 ICTKRPSGVLIQALPHGFSKVTWIEHVVVNDnRVrPHKLYRDLLYGGFGYGARRWTVTLERTCER 461
Cdd:smart00234 143 RAENLPSGLLIEPLGNGPSKVTWVSHADLKG-WL-PHWLVRSLIKSGLAEFAKTLVATLQKHCAK 205
Homeodomain pfam00046
Homeodomain;
27-82 9.64e-19

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 80.24  E-value: 9.64e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15237948    27 KKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAK 82
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
27-85 3.28e-16

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 73.05  E-value: 3.28e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15237948  27 KKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAKSHN 85
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
27-82 3.42e-15

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 70.36  E-value: 3.42e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 15237948     27 KKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAK 82
Cdd:smart00389   2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
7-102 6.24e-15

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 72.85  E-value: 6.24e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948   7 DNSSDERENDVDAntnnRHEKKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAKSHNE 86
Cdd:COG5576  36 DSEMKLERKQDGS----SPPKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRS 111
                        90
                ....*....|....*.
gi 15237948  87 KADNAALRAENIKIRR 102
Cdd:COG5576 112 GKVEQRPGEEEADLAK 127
 
Name Accession Description Interval E-value
START_ArGLABRA2_like cd08875
C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related ...
239-460 5.31e-80

C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins; This subfamily includes the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of the Arabidopsis homeobox protein GLABRA 2 and related proteins. The START domain family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. Most proteins in this subgroup contain an N-terminal homeobox DNA-binding domain, some contain a leucine zipper. ArGLABRA2 plays a role in the differentiation of hairless epidermal cells of the Arabidopsis root. It acts in a cell-position-dependent manner to suppress root hair formation in those cells.


Pssm-ID: 176884  Cd Length: 229  Bit Score: 254.50  E-value: 5.31e-80
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948 239 MLEAAEKAVSEVLSLIQMDDTMWKKSSIDDRLVIDPGLYEKYFTKTNTNGRP----ESSKDVVVVQMDAGNLIDIFLTAE 314
Cdd:cd08875   4 LLELAEEAMDELLKLAQGGEPLWIKSPGMKPEILNPDEYERMFPRHGGSKPGgfttEASRACGLVMMNAIKLVEILMDVN 83
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948 315 KWARLFPTIVNEAKTIHVLDS-VDHRGKTFSRVIYEQLHILSPLVPPREFMILRTCQQIEDNVWMIADVSC-HLPNIEFD 392
Cdd:cd08875  84 KWSELFPGIVSKAKTLQVISTgNGGNRNGTLQLMYAELQVPSPLVPTREFYFLRYCKQLEDGLWAVVDVSIdGVQTAPPP 163
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15237948 393 LSFPICTKRPSGVLIQALPHGFSKVTWIEHVVVNDNRVrpHKLYRDLLYGGFGYGARRWTVTLERTCE 460
Cdd:cd08875 164 ASFVRCRRLPSGCLIQDMPNGYSKVTWVEHVEVDEKPV--HLLYRYLVSSGLAFGATRWVATLQRQCE 229
START pfam01852
START domain;
241-461 3.25e-22

START domain;


Pssm-ID: 426476  Cd Length: 205  Bit Score: 95.16  E-value: 3.25e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948   241 EAAEKAVSEVLSLIQMDDTMWKKSSiddrlvidPGLYEKYFTKTNTNGRPESSKDVVVVQMDAGNLI-DIFLTAEKWArL 319
Cdd:pfam01852   1 ELAEEAAQELLKLALSDEPGWVLLS--------SNENGDVVLQIVEPDHGEASRASGVVPMVAALLVaELLKDMEYRA-Q 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948   320 FPTIVNEAKTIHVLDSvdhrgKTFSRVIYEQLHILSPlVPPREFMILRTCQQIEDNVWMIADVSCHLPNIEFDLSFPICT 399
Cdd:pfam01852  72 WDKDVRSAETLEVISS-----GGDLQYYVAALVAPSP-LSPRDFVFLRYWRRLGGGVYVIVDRSVTHPQFPPSSGYVRAE 145
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15237948   400 KRPSGVLIQALPHGFSKVTWIEHVVVNDNrvRPHKLYRDLLYGGFGYGARRWTVTLERTCER 461
Cdd:pfam01852 146 RLPSGYLIQPCGNGPSKVTWVSHADLKGW--LPSWLLRSLYKSGMPEGAKTWVATLQRLCEK 205
START smart00234
in StAR and phosphatidylcholine transfer protein; putative lipid-binding domain in StAR and ...
243-461 1.47e-19

in StAR and phosphatidylcholine transfer protein; putative lipid-binding domain in StAR and phosphatidylcholine transfer protein


Pssm-ID: 214575  Cd Length: 205  Bit Score: 87.49  E-value: 1.47e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948    243 AEKAVSEVLSLIQMDDTMWKKSSiddrlVIDPGlyEKYFTKTNTNGRP-ESSKDVVVVQMDAGNLI-DIFLTAEKWArLF 320
Cdd:smart00234   2 AEEAAAELLKMAAASEEGWVLSS-----ENENG--DEVRSIFSPGRKPgEAFRLVGVVPMVCADLVeELMDDLEYRP-EW 73
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948    321 PTIVNEAKTIHVLDSVDhrgktfsrVIYeqlHILSP----LVPPREFMILRTCQQIEDNVWMIADVSCHLPNIEFDLSFP 396
Cdd:smart00234  74 DKNVAKAETLEVIDNGT--------VIY---HYVSKfaagPVSPRDFVFVRYWREDEDGSYAVVDVSVTHPTSPPESGYV 142
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15237948    397 ICTKRPSGVLIQALPHGFSKVTWIEHVVVNDnRVrPHKLYRDLLYGGFGYGARRWTVTLERTCER 461
Cdd:smart00234 143 RAENLPSGLLIEPLGNGPSKVTWVSHADLKG-WL-PHWLVRSLIKSGLAEFAKTLVATLQKHCAK 205
Homeodomain pfam00046
Homeodomain;
27-82 9.64e-19

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 80.24  E-value: 9.64e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15237948    27 KKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAK 82
Cdd:pfam00046   1 RRKRTTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
27-85 3.28e-16

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 73.05  E-value: 3.28e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15237948  27 KKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAKSHN 85
Cdd:cd00086   1 RRKRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
27-82 3.42e-15

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 70.36  E-value: 3.42e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 15237948     27 KKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAK 82
Cdd:smart00389   2 RRKRTSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
7-102 6.24e-15

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 72.85  E-value: 6.24e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948   7 DNSSDERENDVDAntnnRHEKKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAKSHNE 86
Cdd:COG5576  36 DSEMKLERKQDGS----SPPKSKRRRTTDEQLMVLEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAKEKKKRS 111
                        90
                ....*....|....*.
gi 15237948  87 KADNAALRAENIKIRR 102
Cdd:COG5576 112 GKVEQRPGEEEADLAK 127
START cd00177
Lipid-binding START domain of mammalian STARD1-STARD15 and related proteins; This family ...
244-423 1.39e-10

Lipid-binding START domain of mammalian STARD1-STARD15 and related proteins; This family includes the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, and related domains, such as the START domain of the Arabidopsis homeobox protein GLABRA 2. The mammalian STARDs are grouped into 8 subfamilies. This family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. For some members of this family, specific lipids that bind in this pocket are known; these include cholesterol (STARD1/STARD3/ STARD4/STARD5), 25-hydroxycholesterol (STARD5), phosphatidylcholine (STARD2/ STARD7/STARD10), phosphatidylethanolamine (STARD10) and ceramides (STARD11). The START domain is found either alone or in association with other domains. Mammalian STARDs participate in the control of various cellular processes including lipid trafficking between intracellular compartments, lipid metabolism, and modulation of signaling events. Mutation or altered expression of STARDs is linked to diseases such as cancer, genetic disorders, and autoimmune disease. The Arabidopsis homeobox protein GLABRA 2 suppresses root hair formation in hairless epidermal root cells.


Pssm-ID: 176851 [Multi-domain]  Cd Length: 193  Bit Score: 61.20  E-value: 1.39e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948 244 EKAVSEVLSLIQmDDTMWKKSSIDDRLvidpglyeKYFTKTNTNGRPESSKDVVVVQMDAGNLIDIFLTAE---KWARLF 320
Cdd:cd00177   1 EEAIEELLELLE-EPEGWKLVKEKDGV--------KIYTKPYEDSGLKLLKAEGVIPASPEQVFELLMDIDlrkKWDKNF 71
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15237948 321 ptivneaKTIHVLDSVDHRgktfSRVIYEQLHiLSPLVPPREFMILRTCQQIEDNVWMIADVSCHLPNIEFDLSFPICTK 400
Cdd:cd00177  72 -------EEFEVIEEIDEH----TDIIYYKTK-PPWPVSPRDFVYLRRRRKLDDGTYVIVSKSVDHDSHPKEKGYVRAEI 139
                       170       180
                ....*....|....*....|...
gi 15237948 401 RPSGVLIQALPHGFSKVTWIEHV 423
Cdd:cd00177 140 KLSGWIIEPLDPGKTKVTYVLQV 162
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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