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Conserved domains on  [gi|1063729056|ref|NP_196664|]
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aberrant root formation protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Kinetochor_Ybp2 super family cl07251
Uncharacterized protein family, YAP/Alf4/glomulin; This entry contains a number of protein ...
45-580 3.71e-69

Uncharacterized protein family, YAP/Alf4/glomulin; This entry contains a number of protein families with apparently unrelated functions. These include the YAP binding proteins of yeasts. These are stress response and redox homeostasis proteins, induced by hydrogen peroxide or induced in response to alkylating agent methyl methanesulphonate (MMS). The family includes Aberrant root formation protein 4 (Alf4) of Arabidopsis thaliana (Mouse-ear cress), which is required for the initiation of lateral roots independent from auxin signalling. It may also function in maintaining the pericycle in the mitotically competent state needed for lateral root formation. The family includes glomulin (FAP68), which is essential for normal development of the vasculature and may represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12.


The actual alignment was detected with superfamily member pfam08568:

Pssm-ID: 400745  Cd Length: 624  Bit Score: 235.45  E-value: 3.71e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056  45 RVRELLAlcfSSVEEAGGFQDFESFVTELVSCLDSLyenvaldanNELENDVIEEVLDEILKVLsspQMDQDVIDALSFH 124
Cdd:pfam08568   2 AVEELLD---PLAEEAPPATDYLTYLTLLELYLEEV---------NEYSIDEKEELLPELLELL---QDNPDLTYEIGWD 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 125 LPKVTSKFADIS----SRCLQLVEEIVDRFVEACNPRDMLSILCEALDAARCY------------HSASTCSTP----LL 184
Cdd:pfam08568  67 LPKLLLKFLPASnvndDPLVKLIMECFEDLARLGNPKELLLKVCELLSELSPEddedsdddkeskKEIEEPFELkqycLL 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 185 HGLSKVFILIQRRHYEQ-LKVAVPIVLNVLKDISLETDVQVEDLFDKALG---------------IASSIRDVSSKLNNE 248
Cdd:pfam08568 147 ELLSSLLKRIQTKYPSRfLAMALSAILNAVTNNPTEETLEDDEFILRRVYtfkrpyipprpasapDPEASSEELSKIKED 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 249 EEAKVRCLLCLYVIQITAIISVSIRDKAASCiplviQLEPFLTSCGLTHLGLITGNDTEKLMSTVAGDDDEFITSFpDIS 328
Cdd:pfam08568 227 ESALQRKLLQSFLTQLLKSYLLSFSVKWDPG-----LLPELIRPGRLLLEDYFEVDEELSERDTILGRLVALATSF-DID 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 329 LGASLLFICAKISHEVAEAANAVLGSVVDELQNNPVKRWQAygMLKYIL------------SSGDLLWEFKR-------- 388
Cdd:pfam08568 301 LSDEFLLFCIKESRPLYESLPKDEDEDKAELFEEVPKDYEA--SYTYSLfkiaiekeipldRHGILLLLTIRyfenelfs 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 389 -------HAIEFLLDIT-----------KGVTSSQCNDEQIDCSDYT--------PGIYATLQ----------------- 425
Cdd:pfam08568 379 lpkisfpDAIYLYLRFTgpslyspffqnKGLEDSLLYWLWVALTSNSielaelpdKVFKVFLQalllitcrqpnpelryi 458
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 426 -------VLSDIPAPHRFDVLRALVTNSRSPSMTAILLGLVKDSMSKSSLQD----------TDCAAVDTHVIELVELVL 488
Cdd:pfam08568 459 tltlltrLLHLHPEDVRFKFIRDTLENCPYESAKGSAIGILKDLMLKALKSSqsselqlpprPNIFLTPHRLSELLSLVL 538
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 489 RPPQGGPPLLP------DQSDAILAALNLYRFALlfesreceagkerskvgSDILSKKNLEKAYKEWLLPLRTLVSCSIA 562
Cdd:pfam08568 539 NSPDGLLNDESnktdlqQNLDLILAYLNLLYYLK-----------------KKWDLRVTLPVFLKEYLEPLKTLLNSSEA 601
                         650
                  ....*....|....*...
gi 1063729056 563 ENLKEDhGQESSLDDVGL 580
Cdd:pfam08568 602 ELEAEK-EPEEKLIDIAN 618
 
Name Accession Description Interval E-value
Kinetochor_Ybp2 pfam08568
Uncharacterized protein family, YAP/Alf4/glomulin; This entry contains a number of protein ...
45-580 3.71e-69

Uncharacterized protein family, YAP/Alf4/glomulin; This entry contains a number of protein families with apparently unrelated functions. These include the YAP binding proteins of yeasts. These are stress response and redox homeostasis proteins, induced by hydrogen peroxide or induced in response to alkylating agent methyl methanesulphonate (MMS). The family includes Aberrant root formation protein 4 (Alf4) of Arabidopsis thaliana (Mouse-ear cress), which is required for the initiation of lateral roots independent from auxin signalling. It may also function in maintaining the pericycle in the mitotically competent state needed for lateral root formation. The family includes glomulin (FAP68), which is essential for normal development of the vasculature and may represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12.


Pssm-ID: 400745  Cd Length: 624  Bit Score: 235.45  E-value: 3.71e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056  45 RVRELLAlcfSSVEEAGGFQDFESFVTELVSCLDSLyenvaldanNELENDVIEEVLDEILKVLsspQMDQDVIDALSFH 124
Cdd:pfam08568   2 AVEELLD---PLAEEAPPATDYLTYLTLLELYLEEV---------NEYSIDEKEELLPELLELL---QDNPDLTYEIGWD 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 125 LPKVTSKFADIS----SRCLQLVEEIVDRFVEACNPRDMLSILCEALDAARCY------------HSASTCSTP----LL 184
Cdd:pfam08568  67 LPKLLLKFLPASnvndDPLVKLIMECFEDLARLGNPKELLLKVCELLSELSPEddedsdddkeskKEIEEPFELkqycLL 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 185 HGLSKVFILIQRRHYEQ-LKVAVPIVLNVLKDISLETDVQVEDLFDKALG---------------IASSIRDVSSKLNNE 248
Cdd:pfam08568 147 ELLSSLLKRIQTKYPSRfLAMALSAILNAVTNNPTEETLEDDEFILRRVYtfkrpyipprpasapDPEASSEELSKIKED 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 249 EEAKVRCLLCLYVIQITAIISVSIRDKAASCiplviQLEPFLTSCGLTHLGLITGNDTEKLMSTVAGDDDEFITSFpDIS 328
Cdd:pfam08568 227 ESALQRKLLQSFLTQLLKSYLLSFSVKWDPG-----LLPELIRPGRLLLEDYFEVDEELSERDTILGRLVALATSF-DID 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 329 LGASLLFICAKISHEVAEAANAVLGSVVDELQNNPVKRWQAygMLKYIL------------SSGDLLWEFKR-------- 388
Cdd:pfam08568 301 LSDEFLLFCIKESRPLYESLPKDEDEDKAELFEEVPKDYEA--SYTYSLfkiaiekeipldRHGILLLLTIRyfenelfs 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 389 -------HAIEFLLDIT-----------KGVTSSQCNDEQIDCSDYT--------PGIYATLQ----------------- 425
Cdd:pfam08568 379 lpkisfpDAIYLYLRFTgpslyspffqnKGLEDSLLYWLWVALTSNSielaelpdKVFKVFLQalllitcrqpnpelryi 458
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 426 -------VLSDIPAPHRFDVLRALVTNSRSPSMTAILLGLVKDSMSKSSLQD----------TDCAAVDTHVIELVELVL 488
Cdd:pfam08568 459 tltlltrLLHLHPEDVRFKFIRDTLENCPYESAKGSAIGILKDLMLKALKSSqsselqlpprPNIFLTPHRLSELLSLVL 538
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 489 RPPQGGPPLLP------DQSDAILAALNLYRFALlfesreceagkerskvgSDILSKKNLEKAYKEWLLPLRTLVSCSIA 562
Cdd:pfam08568 539 NSPDGLLNDESnktdlqQNLDLILAYLNLLYYLK-----------------KKWDLRVTLPVFLKEYLEPLKTLLNSSEA 601
                         650
                  ....*....|....*...
gi 1063729056 563 ENLKEDhGQESSLDDVGL 580
Cdd:pfam08568 602 ELEAEK-EPEEKLIDIAN 618
 
Name Accession Description Interval E-value
Kinetochor_Ybp2 pfam08568
Uncharacterized protein family, YAP/Alf4/glomulin; This entry contains a number of protein ...
45-580 3.71e-69

Uncharacterized protein family, YAP/Alf4/glomulin; This entry contains a number of protein families with apparently unrelated functions. These include the YAP binding proteins of yeasts. These are stress response and redox homeostasis proteins, induced by hydrogen peroxide or induced in response to alkylating agent methyl methanesulphonate (MMS). The family includes Aberrant root formation protein 4 (Alf4) of Arabidopsis thaliana (Mouse-ear cress), which is required for the initiation of lateral roots independent from auxin signalling. It may also function in maintaining the pericycle in the mitotically competent state needed for lateral root formation. The family includes glomulin (FAP68), which is essential for normal development of the vasculature and may represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12.


Pssm-ID: 400745  Cd Length: 624  Bit Score: 235.45  E-value: 3.71e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056  45 RVRELLAlcfSSVEEAGGFQDFESFVTELVSCLDSLyenvaldanNELENDVIEEVLDEILKVLsspQMDQDVIDALSFH 124
Cdd:pfam08568   2 AVEELLD---PLAEEAPPATDYLTYLTLLELYLEEV---------NEYSIDEKEELLPELLELL---QDNPDLTYEIGWD 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 125 LPKVTSKFADIS----SRCLQLVEEIVDRFVEACNPRDMLSILCEALDAARCY------------HSASTCSTP----LL 184
Cdd:pfam08568  67 LPKLLLKFLPASnvndDPLVKLIMECFEDLARLGNPKELLLKVCELLSELSPEddedsdddkeskKEIEEPFELkqycLL 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 185 HGLSKVFILIQRRHYEQ-LKVAVPIVLNVLKDISLETDVQVEDLFDKALG---------------IASSIRDVSSKLNNE 248
Cdd:pfam08568 147 ELLSSLLKRIQTKYPSRfLAMALSAILNAVTNNPTEETLEDDEFILRRVYtfkrpyipprpasapDPEASSEELSKIKED 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 249 EEAKVRCLLCLYVIQITAIISVSIRDKAASCiplviQLEPFLTSCGLTHLGLITGNDTEKLMSTVAGDDDEFITSFpDIS 328
Cdd:pfam08568 227 ESALQRKLLQSFLTQLLKSYLLSFSVKWDPG-----LLPELIRPGRLLLEDYFEVDEELSERDTILGRLVALATSF-DID 300
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 329 LGASLLFICAKISHEVAEAANAVLGSVVDELQNNPVKRWQAygMLKYIL------------SSGDLLWEFKR-------- 388
Cdd:pfam08568 301 LSDEFLLFCIKESRPLYESLPKDEDEDKAELFEEVPKDYEA--SYTYSLfkiaiekeipldRHGILLLLTIRyfenelfs 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 389 -------HAIEFLLDIT-----------KGVTSSQCNDEQIDCSDYT--------PGIYATLQ----------------- 425
Cdd:pfam08568 379 lpkisfpDAIYLYLRFTgpslyspffqnKGLEDSLLYWLWVALTSNSielaelpdKVFKVFLQalllitcrqpnpelryi 458
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 426 -------VLSDIPAPHRFDVLRALVTNSRSPSMTAILLGLVKDSMSKSSLQD----------TDCAAVDTHVIELVELVL 488
Cdd:pfam08568 459 tltlltrLLHLHPEDVRFKFIRDTLENCPYESAKGSAIGILKDLMLKALKSSqsselqlpprPNIFLTPHRLSELLSLVL 538
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063729056 489 RPPQGGPPLLP------DQSDAILAALNLYRFALlfesreceagkerskvgSDILSKKNLEKAYKEWLLPLRTLVSCSIA 562
Cdd:pfam08568 539 NSPDGLLNDESnktdlqQNLDLILAYLNLLYYLK-----------------KKWDLRVTLPVFLKEYLEPLKTLLNSSEA 601
                         650
                  ....*....|....*...
gi 1063729056 563 ENLKEDhGQESSLDDVGL 580
Cdd:pfam08568 602 ELEAEK-EPEEKLIDIAN 618
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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