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Conserved domains on  [gi|15236236|ref|NP_195225|]
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myb domain protein 32 [Arabidopsis thaliana]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 999994)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03091 super family cl33633
hypothetical protein; Provisional
 1-163 1.35e-75

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PLN03091:

Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 237.18  E-value: 1.35e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236    1 MGRSPCCEKDHTNKGAWTKEEDDKLISYIKAHGEGCWRSLPRSAGLQRCGKSCRLRWINYLRPDLKRGNFTLEEDDLIIK 80
Cdd:PLN03091   1 MGRHSCCYKQKLRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236   81 LHSLLGNKWSLIATRLPGRTDNEIKNYWNTHVKRKLLRKGIDPATHRPINETKTSQDSS-DSSKTEDPLVKILSFGPQLE 159
Cdd:PLN03091  81 LHAVLGNRWSQIAAQLPGRTDNEIKNLWNSCLKKKLRQRGIDPNTHKPLSEVENGEDKNpPTDDKSDKASSVVSNELNLL 160


                 ....
gi 15236236  160 KIAN 163
Cdd:PLN03091 161 KADN 164
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 1-163 1.35e-75

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 237.18  E-value: 1.35e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236    1 MGRSPCCEKDHTNKGAWTKEEDDKLISYIKAHGEGCWRSLPRSAGLQRCGKSCRLRWINYLRPDLKRGNFTLEEDDLIIK 80
Cdd:PLN03091   1 MGRHSCCYKQKLRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236   81 LHSLLGNKWSLIATRLPGRTDNEIKNYWNTHVKRKLLRKGIDPATHRPINETKTSQDSS-DSSKTEDPLVKILSFGPQLE 159
Cdd:PLN03091  81 LHAVLGNRWSQIAAQLPGRTDNEIKNLWNSCLKKKLRQRGIDPNTHKPLSEVENGEDKNpPTDDKSDKASSVVSNELNLL 160


                 ....
gi 15236236  160 KIAN 163
Cdd:PLN03091 161 KADN 164
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 11-109 3.04e-16

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 77.91  E-value: 3.04e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236  11 HTNKGAWTKEEDDKLISYIKAHGEGCWRSLPRSAGLqRCGKSCRLRWINYLRPDLKRGNFTLEEDDLIIKLHSLLGNKWS 90
Cdd:COG5147  17 KRKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLIS-STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWS 95

                        90
                ....*....|....*....
gi 15236236  91 LIATRLPGRTDNEIKNYWN 109
Cdd:COG5147  96 TIADYKDRRTAQQCVERYV 114
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 67-111 4.87e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 70.23  E-value: 4.87e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 15236236    67 RGNFTLEEDDLIIKLHSLLGNKWSLIATRLPGRTDNEIKNYWNTH 111
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNY 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
67-114 1.44e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 1.44e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 15236236     67 RGNFTLEEDDLIIKLHSLLG-NKWSLIATRLPGRTDNEIKNYWNTHVKR 114
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 69-112 6.92e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 56.04  E-value: 6.92e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 15236236  69 NFTLEEDDLIIKLHSLLG-NKWSLIATRLPGRTDNEIKNYWNTHV 112
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
PLN03091 PLN03091
hypothetical protein; Provisional
 1-163 1.35e-75

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 237.18  E-value: 1.35e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236    1 MGRSPCCEKDHTNKGAWTKEEDDKLISYIKAHGEGCWRSLPRSAGLQRCGKSCRLRWINYLRPDLKRGNFTLEEDDLIIK 80
Cdd:PLN03091   1 MGRHSCCYKQKLRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236   81 LHSLLGNKWSLIATRLPGRTDNEIKNYWNTHVKRKLLRKGIDPATHRPINETKTSQDSS-DSSKTEDPLVKILSFGPQLE 159
Cdd:PLN03091  81 LHAVLGNRWSQIAAQLPGRTDNEIKNLWNSCLKKKLRQRGIDPNTHKPLSEVENGEDKNpPTDDKSDKASSVVSNELNLL 160


                 ....
gi 15236236  160 KIAN 163
Cdd:PLN03091 161 KADN 164
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 4-166 4.81e-65

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 203.77  E-value: 4.81e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236    4 SPCCEKDHTNKGAWTKEEDDKLISYIKAHGEGCWRSLPRSAGLQRCGKSCRLRWINYLRPDLKRGNFTLEEDDLIIKLHS 83
Cdd:PLN03212  15 TPCCTKMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236   84 LLGNKWSLIATRLPGRTDNEIKNYWNTHVKRKLLRKGIDPATHRPINETKTSQDSSDSSKTEDPLVKILSFGPQLEKIAN 163
Cdd:PLN03212  95 LLGNRWSLIAGRIPGRTDNEIKNYWNTHLRKKLLRQGIDPQTHKPLDANNIHKPEEEVSGGQKYPIEPISSSHTDDTTVN 174


                 ...
gi 15236236  164 FGD 166
Cdd:PLN03212 175 GGD 177
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 11-109 3.04e-16

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 77.91  E-value: 3.04e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15236236  11 HTNKGAWTKEEDDKLISYIKAHGEGCWRSLPRSAGLqRCGKSCRLRWINYLRPDLKRGNFTLEEDDLIIKLHSLLGNKWS 90
Cdd:COG5147  17 KRKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLIS-STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWS 95

                        90
                ....*....|....*....
gi 15236236  91 LIATRLPGRTDNEIKNYWN 109
Cdd:COG5147  96 TIADYKDRRTAQQCVERYV 114
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 67-111 4.87e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 70.23  E-value: 4.87e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 15236236    67 RGNFTLEEDDLIIKLHSLLGNKWSLIATRLPGRTDNEIKNYWNTH 111
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNY 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
67-114 1.44e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 58.00  E-value: 1.44e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 15236236     67 RGNFTLEEDDLIIKLHSLLG-NKWSLIATRLPGRTDNEIKNYWNTHVKR 114
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 14-61 2.91e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 57.13  E-value: 2.91e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 15236236    14 KGAWTKEEDDKLISYIKAHGeGCWRSLPRSAGLqRCGKSCRLRWINYL 61
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLG-NRWKKIAKLLPG-RTDNQCKNRWQNYL 46
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 69-112 6.92e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 56.04  E-value: 6.92e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 15236236  69 NFTLEEDDLIIKLHSLLG-NKWSLIATRLPGRTDNEIKNYWNTHV 112
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 17-75 2.16e-10

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 55.39  E-value: 2.16e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 15236236    17 WTKEEDDKLISYIKAHGEGcWRSLPRSAGlQRCGKSCRLRWINYLRPDLKRGNFTLEED 75
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGND-WKQIAKELG-RRTPKQCFDRWRRKLNPKISRGPWSKEED 57
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
14-63 7.02e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 53.38  E-value: 7.02e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 15236236     14 KGAWTKEEDDKLISYIKAHGEGCWRSLPRSAGLqRCGKSCRLRWINYLRP 63
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPG-RTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 16-61 1.72e-09

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 52.19  E-value: 1.72e-09
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 15236236  16 AWTKEEDDKLISYIKAHGEGCWRSLPRSAGLqRCGKSCRLRWINYL 61
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPG-RTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 70-116 8.95e-08

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 48.08  E-value: 8.95e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 15236236    70 FTLEEDDLIIKLHSLLGNKWSLIATRLPGRTDNEIKNYWNTHVKRKL 116
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKLNPKI 47
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
 63-102 1.50e-03

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 35.75  E-value: 1.50e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|
gi 15236236  63 PDLKRGNFTLEEDDLIIKLHSLLGNKWSLIAtRLPGRTDN 102
Cdd:cd11659   1 PSIKKTEWTREEDEKLLHLAKLLPTQWRTIA-PIVGRTAQ 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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