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Conserved domains on  [gi|30686992|ref|NP_194307|]
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alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

Protein Classification

lipase ROG1 family protein( domain architecture ID 10523695)

lipase ROG1 family protein with an alpha/beta hydrolase fold; similar to Saccharomyces cerevisiae revertant of glycogen synthase kinase mutation protein 1 (ROG1) and lipid droplet phospholipase 1 (LPL1)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF676 pfam05057
Putative serine esterase (DUF676); This family of proteins are probably serine esterase type ...
89-313 3.59e-91

Putative serine esterase (DUF676); This family of proteins are probably serine esterase type enzymes with an alpha/beta hydrolase fold.


:

Pssm-ID: 309968  Cd Length: 212  Bit Score: 273.98  E-value: 3.59e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992    89 EKPDHLVVMVNGIVGSAADWKYAAEQFVKKFPDKVLVHRSESNSATLTFDGVDKMGERLANEVLGVVKHRSGLKKISFVA 168
Cdd:pfam05057   2 SKKDHLVVLVHGLWGNSADMEYVAEQLEKKLPDELIVFLMSSNNVSKTFKGIDVMGERLANEVLEFVQDGSDGKKISFVG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992   169 HSLGGLVARYAIGKLYEQPGEvdsldspskeksaRGGEIAGLEPMNFITFATPHLGSRGHRQFpILCGLPFLERTASQTA 248
Cdd:pfam05057  82 HSLGGLIARYAIGKLYDKAMT-------------FKGFFKGLEPMNFITLASPHLGVLGNSPL-INWGLWFLEKLKKSLS 147
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30686992   249 HLAAGRTGKHLFLVDNDDGNAPLLIRMATDSDDLKFISALNAFKRRVAYANVNFDSMVGWRTSSI 313
Cdd:pfam05057 148 MGQLGKTGRDLFLKDVYDGINSLLYKLLTDESDLKFISALGAFKRRILYANVVNDYIAPLYTSKL 212
 
Name Accession Description Interval E-value
DUF676 pfam05057
Putative serine esterase (DUF676); This family of proteins are probably serine esterase type ...
89-313 3.59e-91

Putative serine esterase (DUF676); This family of proteins are probably serine esterase type enzymes with an alpha/beta hydrolase fold.


Pssm-ID: 309968  Cd Length: 212  Bit Score: 273.98  E-value: 3.59e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992    89 EKPDHLVVMVNGIVGSAADWKYAAEQFVKKFPDKVLVHRSESNSATLTFDGVDKMGERLANEVLGVVKHRSGLKKISFVA 168
Cdd:pfam05057   2 SKKDHLVVLVHGLWGNSADMEYVAEQLEKKLPDELIVFLMSSNNVSKTFKGIDVMGERLANEVLEFVQDGSDGKKISFVG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992   169 HSLGGLVARYAIGKLYEQPGEvdsldspskeksaRGGEIAGLEPMNFITFATPHLGSRGHRQFpILCGLPFLERTASQTA 248
Cdd:pfam05057  82 HSLGGLIARYAIGKLYDKAMT-------------FKGFFKGLEPMNFITLASPHLGVLGNSPL-INWGLWFLEKLKKSLS 147
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30686992   249 HLAAGRTGKHLFLVDNDDGNAPLLIRMATDSDDLKFISALNAFKRRVAYANVNFDSMVGWRTSSI 313
Cdd:pfam05057 148 MGQLGKTGRDLFLKDVYDGINSLLYKLLTDESDLKFISALGAFKRRILYANVVNDYIAPLYTSKL 212
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
88-222 2.41e-11

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 60.23  E-value: 2.41e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992  88 AEKPDHLVVMVNGIVGSAADWKYAAEQFVKK-FPdkVLVHRSESNSATltfdgVDKMGERLANEVLGVVKhRSGLKKISF 166
Cdd:COG1075   1 YAATRYPVVLVHGLGGSAASWAPLAPRLRAAgYP--VYALNYPSTNGS-----IEDSAEQLAAFVDAVLA-ATGAEKVDL 72
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 30686992 167 VAHSLGGLVARYAIgKLYEQPGEVDSLdspskeksarggeiaglepmnfITFATPH 222
Cdd:COG1075  73 VGHSMGGLVARYYL-KRLGGAAKVARV----------------------VTLGTPH 105
 
Name Accession Description Interval E-value
DUF676 pfam05057
Putative serine esterase (DUF676); This family of proteins are probably serine esterase type ...
89-313 3.59e-91

Putative serine esterase (DUF676); This family of proteins are probably serine esterase type enzymes with an alpha/beta hydrolase fold.


Pssm-ID: 309968  Cd Length: 212  Bit Score: 273.98  E-value: 3.59e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992    89 EKPDHLVVMVNGIVGSAADWKYAAEQFVKKFPDKVLVHRSESNSATLTFDGVDKMGERLANEVLGVVKHRSGLKKISFVA 168
Cdd:pfam05057   2 SKKDHLVVLVHGLWGNSADMEYVAEQLEKKLPDELIVFLMSSNNVSKTFKGIDVMGERLANEVLEFVQDGSDGKKISFVG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992   169 HSLGGLVARYAIGKLYEQPGEvdsldspskeksaRGGEIAGLEPMNFITFATPHLGSRGHRQFpILCGLPFLERTASQTA 248
Cdd:pfam05057  82 HSLGGLIARYAIGKLYDKAMT-------------FKGFFKGLEPMNFITLASPHLGVLGNSPL-INWGLWFLEKLKKSLS 147
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30686992   249 HLAAGRTGKHLFLVDNDDGNAPLLIRMATDSDDLKFISALNAFKRRVAYANVNFDSMVGWRTSSI 313
Cdd:pfam05057 148 MGQLGKTGRDLFLKDVYDGINSLLYKLLTDESDLKFISALGAFKRRILYANVVNDYIAPLYTSKL 212
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
88-222 2.41e-11

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 60.23  E-value: 2.41e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992  88 AEKPDHLVVMVNGIVGSAADWKYAAEQFVKK-FPdkVLVHRSESNSATltfdgVDKMGERLANEVLGVVKhRSGLKKISF 166
Cdd:COG1075   1 YAATRYPVVLVHGLGGSAASWAPLAPRLRAAgYP--VYALNYPSTNGS-----IEDSAEQLAAFVDAVLA-ATGAEKVDL 72
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 30686992 167 VAHSLGGLVARYAIgKLYEQPGEVDSLdspskeksarggeiaglepmnfITFATPH 222
Cdd:COG1075  73 VGHSMGGLVARYYL-KRLGGAAKVARV----------------------VTLGTPH 105
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
95-193 2.33e-05

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 45.38  E-value: 2.33e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992  95 VVMVNGIVGSAADWKYAAEQFVKKFpdKVLVH------RSESNSATLTFDgvdkmgeRLANEVLGVVKHRsGLKKISFVA 168
Cdd:COG0596  26 VVLLHGLPGSSYEWRPLIPALAAGY--RVIAPdlrghgRSDKPAGGYTLD-------DLADDLAALLDAL-GLERVVLVG 95
                        90       100
                ....*....|....*....|....*.
gi 30686992 169 HSLGGLVA-RYAIgklyEQPGEVDSL 193
Cdd:COG0596  96 HSMGGMVAlELAA----RHPERVAGL 117
Lipase_2 pfam01674
Lipase (class 2); This family consists of hypothetical C. elegans proteins and lipases. ...
95-180 4.65e-04

Lipase (class 2); This family consists of hypothetical C. elegans proteins and lipases. Lipases or triacylglycerol acylhydrolases hydrolyse ester bonds in triacylglycerol giving diacylglycerol, monoacylglycerol, glycerol and free fatty acids. Swiss:P37957 is an extracellular lipase from B. subtilis 168.


Pssm-ID: 396304 [Multi-domain]  Cd Length: 218  Bit Score: 41.18  E-value: 4.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686992    95 VVMVNGIVGSAAD-WKYAAEQFVKK-FPDKVLV-----HRSESNSATLTFDGVDKMGERlanEVLGVVKHRSGLKKISFV 167
Cdd:pfam01674   4 VIFVHGNSGLAAGgWSKLSQYFKERgYTLAELYattwgDGNESTSLQRAEKCEYVKQIR---RFIEAVLGYTGAAKVDIV 80
                          90
                  ....*....|...
gi 30686992   168 AHSLGGLVARYAI 180
Cdd:pfam01674  81 AHSMGVPIARKAI 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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