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Conserved domains on  [gi|15229000|ref|NP_191234|]
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plant/protein [Arabidopsis thaliana]

Protein Classification

O-fucosyltransferase family protein( domain architecture ID 94843)

O-fucosyltransferase family protein may be involved in glycan metabolism by O-fucosylation of protein substrates

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
O-FucT_like super family cl16914
GDP-fucose protein O-fucosyltransferase and related proteins; O-fucosyltransferase-like ...
 223-366 2.21e-05

GDP-fucose protein O-fucosyltransferase and related proteins; O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.


The actual alignment was detected with superfamily member cd11296:

Pssm-ID: 450121  Cd Length: 206  Bit Score: 45.10  E-value: 2.21e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229000 223 DRSNRSAVMLPYSFLPNMA-------AAKLRNAAEKIKAQL-----GDYDAIHVRRGDKLKTRKDRFGVERIQFPHLDRD 290
Cdd:cd11296  26 ILLGRTLVLPLCLACPIRLvgkhlrfSPEIRKLADRFVRKLlglpgGPYLAVHLRRGDFEVECCHLAKWMGEYLEECLLS 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229000 291 TrpEFILRRIE--KRIPRGRTLFIGSNERKPG-FFSPL-AVRYKLAYSSNFSEILDPII---ENNYQLFMMERLVMMGAk 363
Cdd:cd11296 106 A--EEIAEKIKelMAERKLKVVYVATDEADREeLREELrKAGIRVVTKDDLLEDAELLElekLDNYLLSLVDQEICSRA- 182


                ...
gi 15229000 364 TYF 366
Cdd:cd11296 183 DVF 185
 
Name Accession Description Interval E-value
O-FucT_like cd11296
GDP-fucose protein O-fucosyltransferase and related proteins; O-fucosyltransferase-like ...
 223-366 2.21e-05

GDP-fucose protein O-fucosyltransferase and related proteins; O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.


Pssm-ID: 211383  Cd Length: 206  Bit Score: 45.10  E-value: 2.21e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229000 223 DRSNRSAVMLPYSFLPNMA-------AAKLRNAAEKIKAQL-----GDYDAIHVRRGDKLKTRKDRFGVERIQFPHLDRD 290
Cdd:cd11296  26 ILLGRTLVLPLCLACPIRLvgkhlrfSPEIRKLADRFVRKLlglpgGPYLAVHLRRGDFEVECCHLAKWMGEYLEECLLS 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229000 291 TrpEFILRRIE--KRIPRGRTLFIGSNERKPG-FFSPL-AVRYKLAYSSNFSEILDPII---ENNYQLFMMERLVMMGAk 363
Cdd:cd11296 106 A--EEIAEKIKelMAERKLKVVYVATDEADREeLREELrKAGIRVVTKDDLLEDAELLElekLDNYLLSLVDQEICSRA- 182


                ...
gi 15229000 364 TYF 366
Cdd:cd11296 183 DVF 185
 
Name Accession Description Interval E-value
O-FucT_like cd11296
GDP-fucose protein O-fucosyltransferase and related proteins; O-fucosyltransferase-like ...
 223-366 2.21e-05

GDP-fucose protein O-fucosyltransferase and related proteins; O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.


Pssm-ID: 211383  Cd Length: 206  Bit Score: 45.10  E-value: 2.21e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229000 223 DRSNRSAVMLPYSFLPNMA-------AAKLRNAAEKIKAQL-----GDYDAIHVRRGDKLKTRKDRFGVERIQFPHLDRD 290
Cdd:cd11296  26 ILLGRTLVLPLCLACPIRLvgkhlrfSPEIRKLADRFVRKLlglpgGPYLAVHLRRGDFEVECCHLAKWMGEYLEECLLS 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229000 291 TrpEFILRRIE--KRIPRGRTLFIGSNERKPG-FFSPL-AVRYKLAYSSNFSEILDPII---ENNYQLFMMERLVMMGAk 363
Cdd:cd11296 106 A--EEIAEKIKelMAERKLKVVYVATDEADREeLREELrKAGIRVVTKDDLLEDAELLElekLDNYLLSLVDQEICSRA- 182


                ...
gi 15229000 364 TYF 366
Cdd:cd11296 183 DVF 185
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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