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Conserved domains on  [gi|15229841|ref|NP_189985|]
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Bromo-adjacent homology (BAH) domain-containing protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BAH_plant_3 cd04713
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ...
 64-211 2.48e-83

BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


:

Pssm-ID: 240064  Cd Length: 146  Bit Score: 250.46  E-value: 2.48e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841  64 TGKGQNKKCHYETFEFHGKQYRLKDFVLLYPEDNkQKEYIAIIKDIYSQEKdGLVKMEVQWFYRREDIEEKHFGKWKTEN 143
Cdd:cd04713   1 TGKGKKKKCHYTSFEKDGNKYRLEDCVLLVPEDD-QKPYIAIIKDIYKQEE-GSLKLEVQWLYRPEEIEKKKGGNWKAED 78

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15229841 144 PREIFFSFHCDEVFAESVKYKCLVYFVPDDKQIPNRIHHSGFIVQMVYDNVRKKVRKFSHEGFEEEQK 211
Cdd:cd04713  79 PRELFYSFHRDEVPAESVLHPCKVAFVPKGKQIPLRKGHSGFIVRRVYDNVNKKLWKLTDQDYEDERQ 146
TFIIS_M super family cl47972
Transcription factor S-II (TFIIS), central domain; Transcription elongation by RNA polymerase ...
 286-354 1.48e-05

Transcription factor S-II (TFIIS), central domain; Transcription elongation by RNA polymerase II is regulated by the general elongation factor TFIIS. This factor stimulates RNA polymerase II to transcribe through regions of DNA that promote the formation of stalled ternary complexes. TFIIS is composed of three structural domains, termed I, II, and III. The two C-terminal domains (II and III), this domain and pfam01096 are required for transcription activity.


The actual alignment was detected with superfamily member pfam07500:

Pssm-ID: 462184  Cd Length: 112  Bit Score: 43.73  E-value: 1.48e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15229841   286 MCCESTGTSRKDVVQMVLALEEALYDSFADDVPKYNYKLELLVERLKNSR--VLATRLLNGELKPEQAIKM 354
Cdd:pfam07500  17 LAKDSTEASEEDALELAVEIEEALFKKFGGTNKKYKNKIRSLLFNLKDKKnpDLRRRVLSGEISPEKLVTM 87
 
Name Accession Description Interval E-value
BAH_plant_3 cd04713
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ...
 64-211 2.48e-83

BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240064  Cd Length: 146  Bit Score: 250.46  E-value: 2.48e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841  64 TGKGQNKKCHYETFEFHGKQYRLKDFVLLYPEDNkQKEYIAIIKDIYSQEKdGLVKMEVQWFYRREDIEEKHFGKWKTEN 143
Cdd:cd04713   1 TGKGKKKKCHYTSFEKDGNKYRLEDCVLLVPEDD-QKPYIAIIKDIYKQEE-GSLKLEVQWLYRPEEIEKKKGGNWKAED 78

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15229841 144 PREIFFSFHCDEVFAESVKYKCLVYFVPDDKQIPNRIHHSGFIVQMVYDNVRKKVRKFSHEGFEEEQK 211
Cdd:cd04713  79 PRELFYSFHRDEVPAESVLHPCKVAFVPKGKQIPLRKGHSGFIVRRVYDNVNKKLWKLTDQDYEDERQ 146
BAH pfam01426
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ...
 84-202 5.16e-20

BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.


Pssm-ID: 460207  Cd Length: 120  Bit Score: 84.67  E-value: 5.16e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841    84 YRLKDFVLLYPEDNKQKEYIAIIKDIYSQEKDGLVKMEVQWFYRREDIEEKHfGKWKteNPREIFFSFHCDEVFAESVKY 163
Cdd:pfam01426   3 YSVGDFVLVEPDDADEPYYVARIEELFEDTKNGKKMVRVQWFYRPEETVHRA-GKAF--NKDELFLSDEEDDVPLSAIIG 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 15229841   164 KCLVYFVPD--DKQIPNRIHHSGFIVQMVYDNVRKKVRKFS 202
Cdd:pfam01426  80 KCSVLHKSDleSLDPYKIKEPDDFFCELLYDPKTKSFKKLP 120
BAH smart00439
Bromo adjacent homology domain;
83-202 3.89e-17

Bromo adjacent homology domain;


Pssm-ID: 214664 [Multi-domain]  Cd Length: 121  Bit Score: 76.56  E-value: 3.89e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841     83 QYRLKDFVLLYPEDNKQKEYIAIIKDIYSQEKDGLVKM-EVQWFYRREDIeekHFGKWKTENPREIFFSFHCDEVFAESV 161
Cdd:smart00439   1 TISVGDFVLVEPDDADEPYYIGRIEEIFETKKNSESKMvRVRWFYRPEET---VLEKAALFDKNEVFLSDEYDTVPLSDI 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 15229841    162 KYKCLVYFVPDDKQIPNRIHHSG---FIVQMVYDNVRKKVRKFS 202
Cdd:smart00439  78 IGKCNVLYKSDYPGLRPEGSIGEpdvFFCESAYDPEKGSFKKLP 121
TFIIS_M pfam07500
Transcription factor S-II (TFIIS), central domain; Transcription elongation by RNA polymerase ...
 286-354 1.48e-05

Transcription factor S-II (TFIIS), central domain; Transcription elongation by RNA polymerase II is regulated by the general elongation factor TFIIS. This factor stimulates RNA polymerase II to transcribe through regions of DNA that promote the formation of stalled ternary complexes. TFIIS is composed of three structural domains, termed I, II, and III. The two C-terminal domains (II and III), this domain and pfam01096 are required for transcription activity.


Pssm-ID: 462184  Cd Length: 112  Bit Score: 43.73  E-value: 1.48e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15229841   286 MCCESTGTSRKDVVQMVLALEEALYDSFADDVPKYNYKLELLVERLKNSR--VLATRLLNGELKPEQAIKM 354
Cdd:pfam07500  17 LAKDSTEASEEDALELAVEIEEALFKKFGGTNKKYKNKIRSLLFNLKDKKnpDLRRRVLSGEISPEKLVTM 87
 
Name Accession Description Interval E-value
BAH_plant_3 cd04713
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ...
 64-211 2.48e-83

BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240064  Cd Length: 146  Bit Score: 250.46  E-value: 2.48e-83
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841  64 TGKGQNKKCHYETFEFHGKQYRLKDFVLLYPEDNkQKEYIAIIKDIYSQEKdGLVKMEVQWFYRREDIEEKHFGKWKTEN 143
Cdd:cd04713   1 TGKGKKKKCHYTSFEKDGNKYRLEDCVLLVPEDD-QKPYIAIIKDIYKQEE-GSLKLEVQWLYRPEEIEKKKGGNWKAED 78

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15229841 144 PREIFFSFHCDEVFAESVKYKCLVYFVPDDKQIPNRIHHSGFIVQMVYDNVRKKVRKFSHEGFEEEQK 211
Cdd:cd04713  79 PRELFYSFHRDEVPAESVLHPCKVAFVPKGKQIPLRKGHSGFIVRRVYDNVNKKLWKLTDQDYEDERQ 146
BAH pfam01426
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ...
 84-202 5.16e-20

BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.


Pssm-ID: 460207  Cd Length: 120  Bit Score: 84.67  E-value: 5.16e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841    84 YRLKDFVLLYPEDNKQKEYIAIIKDIYSQEKDGLVKMEVQWFYRREDIEEKHfGKWKteNPREIFFSFHCDEVFAESVKY 163
Cdd:pfam01426   3 YSVGDFVLVEPDDADEPYYVARIEELFEDTKNGKKMVRVQWFYRPEETVHRA-GKAF--NKDELFLSDEEDDVPLSAIIG 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 15229841   164 KCLVYFVPD--DKQIPNRIHHSGFIVQMVYDNVRKKVRKFS 202
Cdd:pfam01426  80 KCSVLHKSDleSLDPYKIKEPDDFFCELLYDPKTKSFKKLP 120
BAH cd04370
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). ...
 81-202 6.01e-20

BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in mammalian DNA methyltransferases and the MTA1 subunits of histone deacetylase complexes. A BAH domain is also found in Yeast Sir3p and in the origin receptor complex protein 1 (Orc1p), where it was found to interact with the N-terminal lobe of the silence information regulator 1 protein (Sir1p), confirming the initial hypothesis that BAH plays a role in protein-protein interactions.


Pssm-ID: 239835 [Multi-domain]  Cd Length: 123  Bit Score: 84.75  E-value: 6.01e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841  81 GKQYRLKDFVLLYPED--NKQKEYIAIIKDIYsQEKDGLVKMEVQWFYRREDIEEKHFGkwkTENPREIFFSFHCDEVFA 158
Cdd:cd04370   1 GITYEVGDSVYVEPDDsiKSDPPYIARIEELW-EDTNGSKQVKVRWFYRPEETPKGLSP---FALRRELFLSDHLDEIPV 76

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 15229841 159 ESVKYKCLVYFVPDD---KQIPNRIHHSGFIVQMVYDNVRKKVRKFS 202
Cdd:cd04370  77 ESIIGKCKVLFVSEFeglKQRPNKIDTDDFFCRLAYDPTTKEFKALE 123
BAH smart00439
Bromo adjacent homology domain;
83-202 3.89e-17

Bromo adjacent homology domain;


Pssm-ID: 214664 [Multi-domain]  Cd Length: 121  Bit Score: 76.56  E-value: 3.89e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841     83 QYRLKDFVLLYPEDNKQKEYIAIIKDIYSQEKDGLVKM-EVQWFYRREDIeekHFGKWKTENPREIFFSFHCDEVFAESV 161
Cdd:smart00439   1 TISVGDFVLVEPDDADEPYYIGRIEEIFETKKNSESKMvRVRWFYRPEET---VLEKAALFDKNEVFLSDEYDTVPLSDI 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 15229841    162 KYKCLVYFVPDDKQIPNRIHHSG---FIVQMVYDNVRKKVRKFS 202
Cdd:smart00439  78 IGKCNVLYKSDYPGLRPEGSIGEpdvFFCESAYDPEKGSFKKLP 121
BAH_BAHCC1 cd04714
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ...
 85-168 1.08e-08

BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240065  Cd Length: 121  Bit Score: 52.79  E-value: 1.08e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841  85 RLKDFVLLYPEDNKQKEYIAIIKDIYsQEKDGLVKMEVQWFYRREdieEKHFGKWKTENPREIFFSFHCDEVFAESVKYK 164
Cdd:cd04714   5 RVGDCVLFKSPGRPSLPYVARIESLW-EDPEGNMVVRVKWYYRPE---ETKGGRKPNHGEKELFASDHQDENSVQTIEHK 80


                ....
gi 15229841 165 CLVY 168
Cdd:cd04714  81 CYVL 84
BAH_plant_1 cd04721
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ...
 81-163 5.53e-06

BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240072  Cd Length: 130  Bit Score: 45.51  E-value: 5.53e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841  81 GKQYRLKDFVLLYPEdnKQKEYIAIIKDIYsQEKDGLVKMEVQWFYRREDieekhFGKW---KTENPREIFFSFHCDEVF 157
Cdd:cd04721   5 GVTISVHDFVYVLSE--EEDRYVAYIEDLY-EDKKGSKMVKVRWFHTTDE-----VGAAlspDSVNPREIFLSPNLQVIS 76


                ....*.
gi 15229841 158 AESVKY 163
Cdd:cd04721  77 VECIDG 82
TFIIS_M pfam07500
Transcription factor S-II (TFIIS), central domain; Transcription elongation by RNA polymerase ...
 286-354 1.48e-05

Transcription factor S-II (TFIIS), central domain; Transcription elongation by RNA polymerase II is regulated by the general elongation factor TFIIS. This factor stimulates RNA polymerase II to transcribe through regions of DNA that promote the formation of stalled ternary complexes. TFIIS is composed of three structural domains, termed I, II, and III. The two C-terminal domains (II and III), this domain and pfam01096 are required for transcription activity.


Pssm-ID: 462184  Cd Length: 112  Bit Score: 43.73  E-value: 1.48e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15229841   286 MCCESTGTSRKDVVQMVLALEEALYDSFADDVPKYNYKLELLVERLKNSR--VLATRLLNGELKPEQAIKM 354
Cdd:pfam07500  17 LAKDSTEASEEDALELAVEIEEALFKKFGGTNKKYKNKIRSLLFNLKDKKnpDLRRRVLSGEISPEKLVTM 87
BAH_Orc1p_like cd04715
BAH, or Bromo Adjacent Homology domain, as present in the Schizosaccharomyces pombe homolog of ...
 62-177 1.07e-03

BAH, or Bromo Adjacent Homology domain, as present in the Schizosaccharomyces pombe homolog of Saccharomyces cerevisiae Orc1p and similar proteins. Orc1 is part of the Yeast Sir1-origin recognition complex, the Orc1p BAH doman functions in epigenetic silencing. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240066  Cd Length: 159  Bit Score: 39.41  E-value: 1.07e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229841  62 KFTGKGQNKKC--HYETFEFHGKQYRLKDFVLLYPEDNkqKEYIAIIKDIYSQEKDGLVKM-EVQWFYRREDIEEKHFGK 138
Cdd:cd04715   6 VKRGEGGKKKDgqFYRSFTYDGVEYRLYDDVYVHNGDS--EPYIGKIIKIYETAIDSGKKKvKVIWFFRPSEIRMELKGE 83

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 15229841 139 WKTeNPREIFFSFHCDEVFA-----ESVKYKCLVYFVPDDKQIP 177
Cdd:cd04715  84 PKR-HINEVFLACGRGEGLAninllESIIGKCNVVCISEDFRNP 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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