NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15224241|ref|NP_181849|]
View 

S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 12042358)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; similar to Arabidopsis thaliana methyltransferase PMTs

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0032259|GO:0008757|GO:0008168|GO:1904047
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 100-608 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


:

Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 852.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   100 NYLPCHDPSTARQY--SIERHYRRERHCPDiAQEKFRCLVPKPTGYKTPFPWPESRKYAWFRNVPFKRLAELKKTQNWVR 177
Cdd:pfam03141   1 DYIPCLDNKRAIKFllSRERMEHRERHCPP-PEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWVK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   178 LEGDRFVFPGGGTSFPGGVKDYVDVILSVLPL--ASGSIRTVLDIGCGVASFGAFLLNYKILTMSIAPRDIHEAQVQFAL 255
Cdd:pfam03141  80 VEGDKFTFPGGGTQFPHGADQYIDFIAQMIPDiaWGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQVQFAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   256 ERGLPAMLGVLSTYKLPYPSRSFDMVHCSRCLVNWTSYDGLYLMEVDRVLRPEGYWVLSGPPVasrvkfknQKRDSKELQ 335
Cdd:pfam03141 160 ERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPV--------YARTEEDLQ 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   336 NQMEKLNDVFRRLCWEKIAESYPVVIWRKPSNHlQCRKRLKALKFPGLC-SSSDPDAAWYKEMEPCITPLPDV-NDTNKT 413
Cdd:pfam03141 232 EIWKEMEDLTKSLCWKLVAKKGDIAIWQKPLNN-SCYNKREPGKKPPLCkDSDDPDAAWYVPMEACITPLPEVsHEVGGG 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   414 VLKNWPERLNHVP-RMKTGSIQGTTIAGFKADTNLWQRRVLYYDTKFK-FLSNGKYRNVIDMNAGLGGFAAALIKYPMWV 491
Cdd:pfam03141 311 WPEPWPARLTAVPpRLSSGQIGGVSPESFKADTELWKKRVNKYKRLLKlGIDWGKVRNVMDMNAGFGGFAAALIDLPVWV 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   492 MNVVPFDlKPNTLGVVYDRGLIGTYMNWCEALSTYPRTYDLIHANGVFSLYLDKCDIVDILLEMQRILRPEGAVIIRDRF 571
Cdd:pfam03141 391 MNVVPVD-SPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYKKRCNLVDILLEMDRILRPEGFVIIRDSV 469

                         490       500       510
                  ....*....|....*....|....*....|....*..
gi 15224241   572 DVLVKVKAITNQMRWNGTMYPEDNSVFDHGTILIVDN 608
Cdd:pfam03141 470 DVLDKVKKIAKAMRWEVRMTDTEDGPHVPEKILIAQK 506
 
Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 100-608 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 852.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   100 NYLPCHDPSTARQY--SIERHYRRERHCPDiAQEKFRCLVPKPTGYKTPFPWPESRKYAWFRNVPFKRLAELKKTQNWVR 177
Cdd:pfam03141   1 DYIPCLDNKRAIKFllSRERMEHRERHCPP-PEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWVK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   178 LEGDRFVFPGGGTSFPGGVKDYVDVILSVLPL--ASGSIRTVLDIGCGVASFGAFLLNYKILTMSIAPRDIHEAQVQFAL 255
Cdd:pfam03141  80 VEGDKFTFPGGGTQFPHGADQYIDFIAQMIPDiaWGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQVQFAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   256 ERGLPAMLGVLSTYKLPYPSRSFDMVHCSRCLVNWTSYDGLYLMEVDRVLRPEGYWVLSGPPVasrvkfknQKRDSKELQ 335
Cdd:pfam03141 160 ERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPV--------YARTEEDLQ 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   336 NQMEKLNDVFRRLCWEKIAESYPVVIWRKPSNHlQCRKRLKALKFPGLC-SSSDPDAAWYKEMEPCITPLPDV-NDTNKT 413
Cdd:pfam03141 232 EIWKEMEDLTKSLCWKLVAKKGDIAIWQKPLNN-SCYNKREPGKKPPLCkDSDDPDAAWYVPMEACITPLPEVsHEVGGG 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   414 VLKNWPERLNHVP-RMKTGSIQGTTIAGFKADTNLWQRRVLYYDTKFK-FLSNGKYRNVIDMNAGLGGFAAALIKYPMWV 491
Cdd:pfam03141 311 WPEPWPARLTAVPpRLSSGQIGGVSPESFKADTELWKKRVNKYKRLLKlGIDWGKVRNVMDMNAGFGGFAAALIDLPVWV 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   492 MNVVPFDlKPNTLGVVYDRGLIGTYMNWCEALSTYPRTYDLIHANGVFSLYLDKCDIVDILLEMQRILRPEGAVIIRDRF 571
Cdd:pfam03141 391 MNVVPVD-SPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYKKRCNLVDILLEMDRILRPEGFVIIRDSV 469

                         490       500       510
                  ....*....|....*....|....*....|....*..
gi 15224241   572 DVLVKVKAITNQMRWNGTMYPEDNSVFDHGTILIVDN 608
Cdd:pfam03141 470 DVLDKVKKIAKAMRWEVRMTDTEDGPHVPEKILIAQK 506
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 198-323 5.89e-11

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 60.78  E-value: 5.89e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 198 DYVDVILSVLPLASGSirTVLDIGCGvasFGAFLLNYKILTMSIAPRDIHEAQVQFALERGLPAMLGV----LSTYKLPY 273
Cdd:COG2226   9 DGREALLAALGLRPGA--RVLDLGCG---TGRLALALAERGARVTGVDISPEMLELARERAAEAGLNVefvvGDAEDLPF 83

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 15224241 274 PSRSFDMVHCSRCLVNWTSYDGLyLMEVDRVLRPEGYWVLS--GPPVASRVK 323
Cdd:COG2226  84 PDGSFDLVISSFVLHHLPDPERA-LAEIARVLKPGGRLVVVdfSPPDLAELE 134
 
Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 100-608 0e+00

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 852.37  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   100 NYLPCHDPSTARQY--SIERHYRRERHCPDiAQEKFRCLVPKPTGYKTPFPWPESRKYAWFRNVPFKRLAELKKTQNWVR 177
Cdd:pfam03141   1 DYIPCLDNKRAIKFllSRERMEHRERHCPP-PEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTKLAEEKGGQNWVK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   178 LEGDRFVFPGGGTSFPGGVKDYVDVILSVLPL--ASGSIRTVLDIGCGVASFGAFLLNYKILTMSIAPRDIHEAQVQFAL 255
Cdd:pfam03141  80 VEGDKFTFPGGGTQFPHGADQYIDFIAQMIPDiaWGGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHEAQVQFAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   256 ERGLPAMLGVLSTYKLPYPSRSFDMVHCSRCLVNWTSYDGLYLMEVDRVLRPEGYWVLSGPPVasrvkfknQKRDSKELQ 335
Cdd:pfam03141 160 ERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPV--------YARTEEDLQ 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   336 NQMEKLNDVFRRLCWEKIAESYPVVIWRKPSNHlQCRKRLKALKFPGLC-SSSDPDAAWYKEMEPCITPLPDV-NDTNKT 413
Cdd:pfam03141 232 EIWKEMEDLTKSLCWKLVAKKGDIAIWQKPLNN-SCYNKREPGKKPPLCkDSDDPDAAWYVPMEACITPLPEVsHEVGGG 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   414 VLKNWPERLNHVP-RMKTGSIQGTTIAGFKADTNLWQRRVLYYDTKFK-FLSNGKYRNVIDMNAGLGGFAAALIKYPMWV 491
Cdd:pfam03141 311 WPEPWPARLTAVPpRLSSGQIGGVSPESFKADTELWKKRVNKYKRLLKlGIDWGKVRNVMDMNAGFGGFAAALIDLPVWV 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   492 MNVVPFDlKPNTLGVVYDRGLIGTYMNWCEALSTYPRTYDLIHANGVFSLYLDKCDIVDILLEMQRILRPEGAVIIRDRF 571
Cdd:pfam03141 391 MNVVPVD-SPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLYKKRCNLVDILLEMDRILRPEGFVIIRDSV 469

                         490       500       510
                  ....*....|....*....|....*....|....*..
gi 15224241   572 DVLVKVKAITNQMRWNGTMYPEDNSVFDHGTILIVDN 608
Cdd:pfam03141 470 DVLDKVKKIAKAMRWEVRMTDTEDGPHVPEKILIAQK 506
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 198-323 5.89e-11

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 60.78  E-value: 5.89e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 198 DYVDVILSVLPLASGSirTVLDIGCGvasFGAFLLNYKILTMSIAPRDIHEAQVQFALERGLPAMLGV----LSTYKLPY 273
Cdd:COG2226   9 DGREALLAALGLRPGA--RVLDLGCG---TGRLALALAERGARVTGVDISPEMLELARERAAEAGLNVefvvGDAEDLPF 83

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 15224241 274 PSRSFDMVHCSRCLVNWTSYDGLyLMEVDRVLRPEGYWVLS--GPPVASRVK 323
Cdd:COG2226  84 PDGSFDLVISSFVLHHLPDPERA-LAEIARVLKPGGRLVVVdfSPPDLAELE 134
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 218-310 6.60e-09

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 53.44  E-value: 6.60e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   218 LDIGCGVASFGAFLLNYKILTMSIaprDIHEAQVQFALERGLPAMLGVL--STYKLPYPSRSFDMVHCSRCLvNWTSYDG 295
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGV---DISPEMLELAREKAPREGLTFVvgDAEDLPFPDNSFDLVLSSEVL-HHVEDPE 76

                          90
                  ....*....|....*
gi 15224241   296 LYLMEVDRVLRPEGY 310
Cdd:pfam08241  77 RALREIARVLKPGGI 91
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 217-309 2.89e-08

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 51.41  E-value: 2.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   217 VLDIGCGVASFGAFL---LNYKILTMsiaprDIHEAQVQFALERGLPAMLGV----LSTYKLPYPSRSFDMVHCSRCLVN 289
Cdd:pfam13649   1 VLDLGCGTGRLTLALarrGGARVTGV-----DLSPEMLERARERAAEAGLNVefvqGDAEDLPFPDGSFDLVVSSGVLHH 75

                          90       100
                  ....*....|....*....|.
gi 15224241   290 WTSYDGL-YLMEVDRVLRPEG 309
Cdd:pfam13649  76 LPDPDLEaALREIARVLKPGG 96
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 215-316 3.58e-07

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 49.25  E-value: 3.58e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 215 RTVLDIGCGvasFGAFLLnykiltmSIAPR-------DIHEAQVQFALERG--LPAMLGVLSTYKLPYPSRSFDMVHCSR 285
Cdd:COG2227  26 GRVLDVGCG---TGRLAL-------ALARRgadvtgvDISPEALEIARERAaeLNVDFVQGDLEDLPLEDGSFDLVICSE 95

                        90       100       110
                ....*....|....*....|....*....|.
gi 15224241 286 CLvNWTSYDGLYLMEVDRVLRPEGYWVLSGP 316
Cdd:COG2227  96 VL-EHLPDPAALLRELARLLKPGGLLLLSTP 125
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
443-567 2.91e-05

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 44.99  E-value: 2.91e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 443 ADTNLWQRRVLYYDTKFKFLSNGKYRNVIDMNAGLGGFAAALIKYpmwVMNVVPFDLKPNTLGVVYDRGLigtYMNWCEA 522
Cdd:COG4976  23 VEDLGYEAPALLAEELLARLPPGPFGRVLDLGCGTGLLGEALRPR---GYRLTGVDLSEEMLAKAREKGV---YDRLLVA 96

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 15224241 523 ----LSTYPRTYDLIHANGVFSlYLDkcDIVDILLEMQRILRPEGAVII 567
Cdd:COG4976  97 dladLAEPDGRFDLIVAADVLT-YLG--DLAAVFAGVARALKPGGLFIF 142
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 185-316 5.20e-05

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 43.76  E-value: 5.20e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 185 FPGGGTSFPGGVKDYVDVILSVLPLASGSirTVLDIGCGVASFGAFL---LNYKILTMsiaprDIHEAQVQFALER---- 257
Cdd:COG2230  25 FEDPDDTLEEAQEAKLDLILRKLGLKPGM--RVLDIGCGWGGLALYLarrYGVRVTGV-----TLSPEQLEYARERaaea 97

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15224241 258 GLPAMLGV-LSTYKLPYPSRSFDMVHCSRCL--VNWTSYDGlYLMEVDRVLRPEGYWVLSGP 316
Cdd:COG2230  98 GLADRVEVrLADYRDLPADGQFDAIVSIGMFehVGPENYPA-YFAKVARLLKPGGRLLLHTP 158
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 216-354 1.89e-04

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 42.02  E-value: 1.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   216 TVLDIGCGvASFGAFLLNYKILTMS-IAPRDIHEAQVQFALER-------GLPAMLGVLSTYKLPYPSRSFDMVHCsRCL 287
Cdd:pfam13847   6 RVLDLGCG-TGHLSFELAEELGPNAeVVGIDISEEAIEKARENaqklgfdNVEFEQGDIEELPELLEDDKFDVVIS-NCV 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15224241   288 VNWTSYDGLYLMEVDRVLRPEGYwVLSGPPVASRVKFKNQKRDSKELQNQMEKLNDVFRRLCWEKIA 354
Cdd:pfam13847  84 LNHIPDPDKVLQEILRVLKPGGR-LIISDPDSLAELPAHVKEDSTYYAGCVGGAILKKKLYELLEEA 149
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
197-314 2.42e-04

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 42.29  E-value: 2.42e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 197 KDYVDVILSVLPLASGsiRTVLDIGCGVASFGAFLLNYKILTMSIaprDIHEAQVQFALERGLPAMLGVLSTYKLPYPSR 276
Cdd:COG4976  32 ALLAEELLARLPPGPF--GRVLDLGCGTGLLGEALRPRGYRLTGV---DLSEEMLAKAREKGVYDRLLVADLADLAEPDG 106

                        90       100       110       120
                ....*....|....*....|....*....|....*....|.
gi 15224241 277 SFDMVHCSRCLvnwtSYDG---LYLMEVDRVLRPEGYWVLS 314
Cdd:COG4976 107 RFDLIVAADVL----TYLGdlaAVFAGVARALKPGGLFIFS 143
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 520-563 6.03e-04

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 39.47  E-value: 6.03e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 15224241   520 CEALSTYPRTYDLIHANGVFSlYLDKCDIVDILLEMQRILRPEG 563
Cdd:pfam13649  54 AEDLPFPDGSFDLVVSSGVLH-HLPDPDLEAALREIARVLKPGG 96
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 218-310 8.33e-04

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 38.89  E-value: 8.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241   218 LDIGCGVASFGAFLLNYKILTMSIApRDIHEAQVQFALERGLPAMLGVLSTYKLP------YPSRSFDMVHCSRCLvNWT 291
Cdd:pfam08242   1 LEIGCGTGTLLRALLEALPGLEYTG-LDISPAALEAARERLAALGLLNAVRVELFqldlgeLDPGSFDVVVASNVL-HHL 78

                          90
                  ....*....|....*....
gi 15224241   292 SYDGLYLMEVDRVLRPEGY 310
Cdd:pfam08242  79 ADPRAVLRNIRRLLKPGGV 97
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 448-569 1.99e-03

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 38.82  E-value: 1.99e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 448 WQRRVLYYDTKFKF---LSNGKYRNVIDMNAGLGGFAAALIKYpmwVMNVVPFDLKPNTLGV----VYDRGLIGTYMNW- 519
Cdd:COG2226   1 FDRVAARYDGREALlaaLGLRPGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELarerAAEAGLNVEFVVGd 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 15224241 520 CEALSTYPRTYDLIHANGVFSlYLDkcDIVDILLEMQRILRPEGAVIIRD 569
Cdd:COG2226  78 AEDLPFPDGSFDLVISSFVLH-HLP--DPERALAEIARVLKPGGRLVVVD 124
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 191-357 2.95e-03

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 39.51  E-value: 2.95e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 191 SFPGGVKDYVDVILSVLPLASGSIRtVLDIGCGVASFGAFL---LNYKILTMSIAPRDIHEAQvQFALERGLPAMLGVLS 267
Cdd:COG0500   5 YYSDELLPGLAALLALLERLPKGGR-VLDLGCGTGRNLLALaarFGGRVIGIDLSPEAIALAR-ARAAKAGLGNVEFLVA 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15224241 268 TYK--LPYPSRSFDMVhCSRCLVNWTSYDGL--YLMEVDRVLRPEGYWVLSgPPVASRVKFKNQKRDSKELQNQMEKLND 343
Cdd:COG0500  83 DLAelDPLPAESFDLV-VAFGVLHHLPPEEReaLLRELARALKPGGVLLLS-ASDAAAALSLARLLLLATASLLELLLLL 160

                       170
                ....*....|....
gi 15224241 344 VFRRLCWEKIAESY 357
Cdd:COG0500 161 RLLALELYLRALLA 174
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 520-563 5.52e-03

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 36.58  E-value: 5.52e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 15224241   520 CEALSTYPRTYDLIHANGVFSlYLDkcDIVDILLEMQRILRPEG 563
Cdd:pfam08242  56 LDLGELDPGSFDVVVASNVLH-HLA--DPRAVLRNIRRLLKPGG 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH