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Conserved domains on  [gi|15220732|ref|NP_174326|]
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alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03037 PLN03037
lipase class 3 family protein; Provisional
 1-529 0e+00

lipase class 3 family protein; Provisional


:

Pssm-ID: 215547  Cd Length: 525  Bit Score: 969.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732    1 MENALVKTPLRKLRRRRTKRVWRlkQKLKLAWKSIKIRVKSHLpgflstKKHLFHIKSRKEEQDLSQV-------AQRIC 73
Cdd:PLN03037   1 MENALVKTPVTSRKLRRRKTKRV--WKLKLAWKAIKKAVKSHL------KKHLLHMKCRKEEKQLSQVsdggqlqAERIK 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732   74 KISNDSTKSLAFLLQLPkYSADDFLDRGDLMTPAASPREKISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVY 153
Cdd:PLN03037  73 KISNHSTKSLAFLLQLP-YTADDFIDRGDLMTPTRSPRENISKMWREIHGSNNWENLLDPLHPWLRREVVKYGEFVEATY 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  154 DSLDFDPLSEFCGSSRYNRNKLFEELGLTRHGYKVTKYIYAMSRVDVPQWFLSSALGETWSKDSNWMGFVAVSGDRESLR 233
Cdd:PLN03037 152 DAFDFDPLSEFCGSCRYNRHKLFEELGLTKHGYKVTKYIYAMSHVDVPQWFLRSATGETWSKDSNWMGFVAVSGDRESQR 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  234 IGRRDIVVAWRGTVTPTEWFMDLRTSMEPFDCEGKHGKTVVKVQSGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFF 313
Cdd:PLN03037 232 IGRRDIVVAWRGTVAPTEWFMDLRTSLEPFDCDGDHGKNVVKVQSGFLSIYKSKSELTRYNKLSASEQVMEEVKRLVNFF 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  314 KDRGEEVSLTITGHSLGGALALMNAYEAARDVPALSgNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPG 393
Cdd:PLN03037 312 KDRGEEVSLTITGHSLGGALALLNAYEAARSVPALS-NISVISFGAPRVGNLAFKEKLNELGVKVLRVVNKQDIVPKLPG 390

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  394 IVFNKVLNKLNPITSRLNWVYRHVGTQLKLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVASVNK 473
Cdd:PLN03037 391 IIFNKILNKLNPITSRLNWVYRHVGTQLKLDMFSSPYLKRESDLGGAHNLEVYLHLLDGFHGKKLGFRWNARRDLALVNK 470

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15220732  474 STDMLLDHLRIPEFWYQVAHKGLILNKQtGRWVKPVRAPEDIPSPLPTGPKPIYSL 529
Cdd:PLN03037 471 STDMLIEELRIPEFWYQVPHKGLVLNKQ-GRWVKPVRAPEDIPSPFSTGPKPIYIL 525
 
Name Accession Description Interval E-value
PLN03037 PLN03037
lipase class 3 family protein; Provisional
 1-529 0e+00

lipase class 3 family protein; Provisional


Pssm-ID: 215547  Cd Length: 525  Bit Score: 969.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732    1 MENALVKTPLRKLRRRRTKRVWRlkQKLKLAWKSIKIRVKSHLpgflstKKHLFHIKSRKEEQDLSQV-------AQRIC 73
Cdd:PLN03037   1 MENALVKTPVTSRKLRRRKTKRV--WKLKLAWKAIKKAVKSHL------KKHLLHMKCRKEEKQLSQVsdggqlqAERIK 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732   74 KISNDSTKSLAFLLQLPkYSADDFLDRGDLMTPAASPREKISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVY 153
Cdd:PLN03037  73 KISNHSTKSLAFLLQLP-YTADDFIDRGDLMTPTRSPRENISKMWREIHGSNNWENLLDPLHPWLRREVVKYGEFVEATY 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  154 DSLDFDPLSEFCGSSRYNRNKLFEELGLTRHGYKVTKYIYAMSRVDVPQWFLSSALGETWSKDSNWMGFVAVSGDRESLR 233
Cdd:PLN03037 152 DAFDFDPLSEFCGSCRYNRHKLFEELGLTKHGYKVTKYIYAMSHVDVPQWFLRSATGETWSKDSNWMGFVAVSGDRESQR 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  234 IGRRDIVVAWRGTVTPTEWFMDLRTSMEPFDCEGKHGKTVVKVQSGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFF 313
Cdd:PLN03037 232 IGRRDIVVAWRGTVAPTEWFMDLRTSLEPFDCDGDHGKNVVKVQSGFLSIYKSKSELTRYNKLSASEQVMEEVKRLVNFF 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  314 KDRGEEVSLTITGHSLGGALALMNAYEAARDVPALSgNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPG 393
Cdd:PLN03037 312 KDRGEEVSLTITGHSLGGALALLNAYEAARSVPALS-NISVISFGAPRVGNLAFKEKLNELGVKVLRVVNKQDIVPKLPG 390

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  394 IVFNKVLNKLNPITSRLNWVYRHVGTQLKLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVASVNK 473
Cdd:PLN03037 391 IIFNKILNKLNPITSRLNWVYRHVGTQLKLDMFSSPYLKRESDLGGAHNLEVYLHLLDGFHGKKLGFRWNARRDLALVNK 470

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15220732  474 STDMLLDHLRIPEFWYQVAHKGLILNKQtGRWVKPVRAPEDIPSPLPTGPKPIYSL 529
Cdd:PLN03037 471 STDMLIEELRIPEFWYQVPHKGLVLNKQ-GRWVKPVRAPEDIPSPFSTGPKPIYIL 525
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 171-451 9.02e-52

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 176.13  E-value: 9.02e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 171 NRNKLFEELGLTRHGYKVTKYIYAMSRVDvPQWFLSSALG----ETWSKDSNWMGFVAVSGDReslrigrRDIVVAWRGT 246
Cdd:cd00519   1 DYEKLKYYAKLAAAAYCVDANILAKAVVF-ADIALLNVFSpdklLKTDKQYDTQGYVAVDHDR-------KTIVIAFRGT 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 247 VTPTEWFMDLRTSMEPFDCEGKHGktvVKVQSGFLSIYNSKSELTRYNKESASEQtmdevkrlvnffkdrGEEVSLTITG 326
Cdd:cd00519  73 VSLADWLTDLDFSPVPLDPPLCSG---GKVHSGFYSAYKSLYNQVLPELKSALKQ---------------YPDYKIIVTG 134

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 327 HSLGGALALMNAYEAARDVPalSGNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPgivfnkvlnklnPI 406
Cdd:cd00519 135 HSLGGALASLLALDLRLRGP--GSDVTVYTFGQPRVGNAAFAEYLESTKGRVYRVVHGNDIVPRLP------------PG 200

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*
gi 15220732 407 TSRLNWVYRHVGTQLKLDvfsspyvkrdsdlgraHNLEVYLHVLD 451
Cdd:cd00519 201 SLTPPEGYTHVGTEVWID----------------HLPYFYIDALC 229
Lipase_3 pfam01764
Lipase (class 3);
240-395 5.12e-47

Lipase (class 3);


Pssm-ID: 396362 [Multi-domain]  Cd Length: 139  Bit Score: 160.12  E-value: 5.12e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732   240 VVAWRGTVTPTEWFMDLRTSMEPFDCEGKHGktvVKVQSGFLSIYnskseltrynkESASEQTMDEVKRLVNFFKDrgee 319
Cdd:pfam01764   1 VVAFRGTNSILDWLTDFDFSLTPFKDFFLGG---GKVHSGFLSAY-----------TSVREQVLAELKRLLEKYPD---- 62

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15220732   320 VSLTITGHSLGGALALMNAYEAARDVPALSGNISVISFGAPRVGNLAFKEKLNSLGVK-VLRVVNKQDIVPKLPGIV 395
Cdd:pfam01764  63 YSIVVTGHSLGGALASLAALDLVENGLRLSSRVTVVTFGQPRVGNLEFAKLHDSQGPKfSYRVVHQRDIVPRLPPIV 139
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
235-448 2.01e-25

Predicted lipase [Lipid transport and metabolism];


Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 105.61  E-value: 2.01e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 235 GRRDIVVAWRGTVTPTEWFMDLRTSMEPFdcegKHGKTVVKVQSGFLSIYNSkseltrynkesASEQTMDEVKRLvnffk 314
Cdd:COG3675  25 SDDEVIVAFRGTESLTDWLTNLNAAQVPY----PFAKTGGKVHRGFYRALQS-----------LRELLEDALRPL----- 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 315 drGEEVSLTITGHSLGGALALMNAYEAARDVPalSGNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPgi 394
Cdd:COG3675  85 --SPGKRLYVTGHSLGGALATLAAADLERNYI--FPVRGLYTFGQPRVGDRSFAKYYNLHVPNSYRIVNNNDIVPLLP-- 158

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 15220732 395 vfnkvlnklnpitsRLNWVYRHVGTQLKLDVFSSPYVKRDSDLGRAHNLEVYLH 448
Cdd:COG3675 159 --------------PVWMGYDHVGKLLWLDSLRKDMLTDHSMDNYIHHTDLSQL 198
 
Name Accession Description Interval E-value
PLN03037 PLN03037
lipase class 3 family protein; Provisional
 1-529 0e+00

lipase class 3 family protein; Provisional


Pssm-ID: 215547  Cd Length: 525  Bit Score: 969.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732    1 MENALVKTPLRKLRRRRTKRVWRlkQKLKLAWKSIKIRVKSHLpgflstKKHLFHIKSRKEEQDLSQV-------AQRIC 73
Cdd:PLN03037   1 MENALVKTPVTSRKLRRRKTKRV--WKLKLAWKAIKKAVKSHL------KKHLLHMKCRKEEKQLSQVsdggqlqAERIK 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732   74 KISNDSTKSLAFLLQLPkYSADDFLDRGDLMTPAASPREKISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVY 153
Cdd:PLN03037  73 KISNHSTKSLAFLLQLP-YTADDFIDRGDLMTPTRSPRENISKMWREIHGSNNWENLLDPLHPWLRREVVKYGEFVEATY 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  154 DSLDFDPLSEFCGSSRYNRNKLFEELGLTRHGYKVTKYIYAMSRVDVPQWFLSSALGETWSKDSNWMGFVAVSGDRESLR 233
Cdd:PLN03037 152 DAFDFDPLSEFCGSCRYNRHKLFEELGLTKHGYKVTKYIYAMSHVDVPQWFLRSATGETWSKDSNWMGFVAVSGDRESQR 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  234 IGRRDIVVAWRGTVTPTEWFMDLRTSMEPFDCEGKHGKTVVKVQSGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFF 313
Cdd:PLN03037 232 IGRRDIVVAWRGTVAPTEWFMDLRTSLEPFDCDGDHGKNVVKVQSGFLSIYKSKSELTRYNKLSASEQVMEEVKRLVNFF 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  314 KDRGEEVSLTITGHSLGGALALMNAYEAARDVPALSgNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPG 393
Cdd:PLN03037 312 KDRGEEVSLTITGHSLGGALALLNAYEAARSVPALS-NISVISFGAPRVGNLAFKEKLNELGVKVLRVVNKQDIVPKLPG 390

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  394 IVFNKVLNKLNPITSRLNWVYRHVGTQLKLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVASVNK 473
Cdd:PLN03037 391 IIFNKILNKLNPITSRLNWVYRHVGTQLKLDMFSSPYLKRESDLGGAHNLEVYLHLLDGFHGKKLGFRWNARRDLALVNK 470

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15220732  474 STDMLLDHLRIPEFWYQVAHKGLILNKQtGRWVKPVRAPEDIPSPLPTGPKPIYSL 529
Cdd:PLN03037 471 STDMLIEELRIPEFWYQVPHKGLVLNKQ-GRWVKPVRAPEDIPSPFSTGPKPIYIL 525
PLN02310 PLN02310
triacylglycerol lipase
 104-519 0e+00

triacylglycerol lipase


Pssm-ID: 215176  Cd Length: 405  Bit Score: 636.64  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  104 MTPAASPREKISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVYDSLDFDPLSEFCGSSRYNRNKLFEELGLTR 183
Cdd:PLN02310   1 MTPTRYLEENMSNKWHEIHGSSNWEHLLDPLHPWLRREILKYGEFAQATYDAFDFDPLSEYCGSCRYNRHKLFETLGLTK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  184 HGYKVTKYIYAMSRVDVPQWFLSSAlgETWSKDSNWMGFVAVSGDRESLRIGRRDIVVAWRGTVTPTEWFMDLRTSMEPF 263
Cdd:PLN02310  81 HGYKVKKYIYALSHVDVPHWLKRSQ--ATWSKDSNWMGYVAVSRDEESQRIGRRDIMVAWRGTVAPSEWFLDLETKLEHI 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  264 DcegkhgKTVVKVQSGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFFKDRGEEVSLTITGHSLGGALALMNAYEAAR 343
Cdd:PLN02310 159 D------NTNVKVQEGFLKIYKSKDESTRYNKLSASEQVMQEVKRLVNFYRGKGEEVSLTVTGHSLGGALALLNAYEAAT 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  344 DVPALSgnISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPGIVfNKVLNKLNPITSRLNWVYRHVGTQLKL 423
Cdd:PLN02310 233 TIPDLF--VSVISFGAPRVGNIAFKEKLNELGVKTLRVVVKQDKVPKLPGLL-NKMLNKFHGLTGKLNWVYRHVGTQLKL 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  424 DVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVASVNKSTDMLLDHLRIPEFWYQVAHKGLILNkQTG 503
Cdd:PLN02310 310 DAFSSPYLKRESDLSGCHNLELYLHLIDGFHSEDSKFRWNARRDLALVNKGSDMLIEDLGIPEFWYQFPYKGLMLN-TYG 388

                        410
                 ....*....|....*..
gi 15220732  504 RWVKPVRA-PEDIPSPL 519
Cdd:PLN02310 389 RWVKPGRVdQEDIFSSI 405
PLN02761 PLN02761
lipase class 3 family protein
 72-515 1.33e-136

lipase class 3 family protein


Pssm-ID: 215406 [Multi-domain]  Cd Length: 527  Bit Score: 405.97  E-value: 1.33e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732   72 ICKISNDSTKSLAFLLQLPKYSADDFLDRGDlMTPAASPREK---ISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEF 148
Cdd:PLN02761  43 ICSSSCTSISSSTTQQKQSNKQTHVSDNKRE-EEPEEELEEKevsLREIWREVQGCNNWEGLLDPMNNHLRREIIRYGEF 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  149 VESVYDSLDFDPLSEFCGSSRYNRNKLFEELGLTRH-GYKVTKYIYAMSRVDVPQWFLSSALGETWSKDSNWMGFVAVSG 227
Cdd:PLN02761 122 AQACYDSFDFDPHSKYCGSCKYHPSDFFQNLDLHLHkGYTITRYLYATSNINLPNFFQKSKLSSIWSQHANWMGYVAVAT 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  228 DRESL-RIGRRDIVVAWRGTVTPTEWFMDLRTSMepfdCEGKHGKT-VVKVQSGFLSIYNSKSELTRYNKESASEQTMDE 305
Cdd:PLN02761 202 DEEEVkRLGRRDIVIAWRGTVTYLEWIYDLKDIL----CSANFGDDpSIKIELGFHDLYTKKEDSCKFSSFSAREQVLAE 277

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  306 VKRLVNFF--KDRGEEVSLTITGHSLGGALALMNAYEAAR----DVPALSGN--ISVISFGAPRVGNLAFKEKLNSLGVK 377
Cdd:PLN02761 278 VKRLVEYYgtEEEGHEISITVTGHSLGASLALVSAYDIAElnlnHVPENNYKipITVFSFSGPRVGNLRFKERCDELGVK 357

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  378 VLRVVNKQDIVPKLPGIVFNKVL--NKLNPITSRLNWVYRHVGTQLKLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHR 455
Cdd:PLN02761 358 VLRVVNVHDKVPSVPGIFTNEKFqfQKYVEEKTSFPWSYAHVGVELALDHKKSPFLKPTKDLGCAHNLEALLHLVDGYHG 437

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  456 K----KSGFRVNARRDVASVNKSTDMLLDHLRIPEFWYQVAHKGLILNKQtGRWVKPVR------APEDI 515
Cdd:PLN02761 438 KdeeaEKRFCLVTKRDIALVNKSCDFLRSEYHVPPCWRQDENKGMVKASD-GRWVLPDRprlephGPEDI 506
PLN02719 PLN02719
triacylglycerol lipase
 108-514 3.21e-128

triacylglycerol lipase


Pssm-ID: 178321  Cd Length: 518  Bit Score: 384.05  E-value: 3.21e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  108 ASPREKISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVYDSLDFDPLSEFCGSSRYNRNKLFEELGLTRHGYK 187
Cdd:PLN02719  82 AKESKRLRDTWRKIQGEDDWAGLMDPMDPVLRSELIRYGEMAQACYDAFDFDPFSRYCGSCRFTRRHLFDSLGIIDSGYE 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  188 VTKYIYAMSRVDVPQWFLSSALGETWSKDSNWMGFVAVSGDRESL--RIGRRDIVVAWRGTVTPTEWFMDLRTSMEPFDC 265
Cdd:PLN02719 162 VARYLYATSNINLPNFFSKSRWSKVWSKNANWIGYVAVSDDDEATrcRLGRRDIAIAWRGTVTRLEWIADLKDFLKPVSG 241

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  266 EG-KHGKTVVKVQSGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFFKD-RGEEVSLTITGHSLGGALALMNAYEAA- 342
Cdd:PLN02719 242 NGfRCPDPAVKAESGFLDLYTDKDTCCNFSKFSAREQVLTEVKRLVERYGDeEGEELSITVTGHSLGGALAVLSAYDVAe 321

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  343 ----RDVPALSGNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPGIVFN-KVLNKLNPITSRLNWVYRHV 417
Cdd:PLN02719 322 mglnRTRKGKVIPVTAFTYGGPRVGNIRFKERIEELGVKVLRVVNEHDVVAKSPGLFLNeRAPQALMKLAGGLPWCYSHV 401

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  418 GTQLKLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVASVNKSTDMLLDHLRIPEFWYQVAHKGLI 497
Cdd:PLN02719 402 GEMLPLDHQKSPFLKPTVDLSTAHNLEALLHLLDGYHGKGQRFVLSSGRDPALVNKASDFLKDHFMVPPYWRQDANKGMV 481

                        410
                 ....*....|....*..
gi 15220732  498 LNKQtGRWVKPVRAPED 514
Cdd:PLN02719 482 RNTD-GRWIQPDRIRAD 497
PLN02753 PLN02753
triacylglycerol lipase
 58-518 6.96e-127

triacylglycerol lipase


Pssm-ID: 178354  Cd Length: 531  Bit Score: 380.98  E-value: 6.96e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732   58 SRKEEQDLSQVaqrICKISNDSTKSLAFLLQLPKYSADDFLDRGDLMTPAASPRE--KISKMWRELHGSNNWENLLDPLH 135
Cdd:PLN02753  48 SRTDESSLSAV---ISRLERERRERQGLLIDEAEGAGELWLTAEDIRRRDKKTEEerRLRDTWRKIQGEDDWAGLIDPMD 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  136 PWLRREVTKYGEFVESVYDSLDFDPLSEFCGSSRYNRNKLFEELGLTRHGYKVTKYIYAMSRVDVPQWFLSSALGETWSK 215
Cdd:PLN02753 125 PILRSELIRYGEMAQACYDAFDFDPASKYCGTSRFSRLDFFDSLGMIDSGYEVARYLYATSNINLPNFFSKSRWSKVWSK 204

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  216 DSNWMGFVAVSGDRESL-RIGRRDIVVAWRGTVTPTEWFMDLRTSMEPFDCEG-KHGKTVVKVQSGFLSIYNSKSELTRY 293
Cdd:PLN02753 205 NANWMGYVAVSDDETSRnRLGRRDIAIAWRGTVTKLEWIADLKDYLKPVSENKiRCPDPAVKVESGFLDLYTDKDTTCKF 284

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  294 NKESASEQTMDEVKRLVNFFKDRGE-EVSLTITGHSLGGALALMNAYEAARDVPALSGN-----ISVISFGAPRVGNLAF 367
Cdd:PLN02753 285 AKFSAREQILTEVKRLVEEHGDDDDsDLSITVTGHSLGGALAILSAYDIAEMGLNRSKKgkvipVTVLTYGGPRVGNVRF 364

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  368 KEKLNSLGVKVLRVVNKQDIVPKLPGIVFNKVL-NKLNPITSRLNWVYRHVGTQLKLDVFSSPYVKRDSDLGRAHNLEVY 446
Cdd:PLN02753 365 KDRMEELGVKVLRVVNVHDVVPKSPGLFLNESRpHALMKIAEGLPWCYSHVGEELALDHQNSPFLKPSVDLSTAHNLEAM 444

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15220732  447 LHVLDGFHRKKSGFRVNARRDVASVNKSTDMLLDHLRIPEFWYQVAHKGLILNKQtGRWVKPVR-APEDIPSP 518
Cdd:PLN02753 445 LHLLDGYHGKGERFVLSSGRDHALVNKASDFLKEHLQIPPFWRQDANKGMVRNSE-GRWIQAERlRFEDHHSP 516
PLN02802 PLN02802
triacylglycerol lipase
 104-469 1.37e-112

triacylglycerol lipase


Pssm-ID: 215432  Cd Length: 509  Bit Score: 343.68  E-value: 1.37e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  104 MTPAASPREKISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVYDSLDFDPLSEFCGSSRYNRnklfeeLGLTR 183
Cdd:PLN02802 123 KSEEPSPRGTIASRWRELHGENGWEGLLDPLDENLRRELVRYGEFVQAAYHAFHSNPAMSAEAPGRPRH------VALPD 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  184 HGYKVTKYIYAMSRVDVPQWFLSSALGETWSKDSNWMGFVAVSGD-RESLRIGRRDIVVAWRGTVTPTEWFMDLRTSMEP 262
Cdd:PLN02802 197 RSYRVTKSLFATSSVGLPKWADDVAPDGWMTQRSSWVGYVAVCDSpREIRRMGRRDIVIALRGTATCLEWAENLRAGLVP 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  263 FDCEGKHGKTVV--KVQSGFLSIYNSKSEltryNKESASEQTMDEVKRLVNFFKdrGEEVSLTITGHSLGGALALMNAYE 340
Cdd:PLN02802 277 MPGDDDDAGDQEqpKVECGFLSLYKTAGA----HVPSLSESVVGEVRRLMEKYK--GEELSITVTGHSLGAALALLVADE 350

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  341 AARDVPALSgNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPGIVFNKVLNKlnpitsrlnWVYRHVGTQ 420
Cdd:PLN02802 351 LATCVPAAP-PVAVFSFGGPRVGNRAFADRLNARGVKVLRVVNAQDVVTRVPGIAPREELHK---------WAYAHVGAE 420

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 15220732  421 LKLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVA 469
Cdd:PLN02802 421 LRLDSKMSPYLRPDADVACCHDLEAYLHLVDGFLGSNCPFRANAKRSLL 469
PLN02571 PLN02571
triacylglycerol lipase
 114-505 2.96e-97

triacylglycerol lipase


Pssm-ID: 215309  Cd Length: 413  Bit Score: 300.65  E-value: 2.96e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  114 ISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVYDSLDFDPLSEFCGSSRYNRNKLFEELGLTR---HGYKVTK 190
Cdd:PLN02571  18 IAKRWRHLSGQNHWKGLLDPLDQDLREYIIHYGEMAQATYDTFNIQKASKFAGSSLYAKKDFFAKVGLEKgnpYKYKVTK 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  191 YIYAMSRVDVPQWFLSSALG-ETWSKDSNWMGFVAVSGDRESLRIGRRDIVVAWRGTVTPTEWFMDLRTSMEPFDCEGKH 269
Cdd:PLN02571  98 FLYATSQIHVPEAFILKSLSrEAWSKESNWMGYVAVATDEGKALLGRRDIVIAWRGTVQTLEWVNDFEFNLVSASKIFGE 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  270 GKTVVKVQSGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFFKDrgEEVSLTITGHSLGGALALMNA-------YEAA 342
Cdd:PLN02571 178 SNDQPKVHQGWYSIYTSDDERSPFNKTSARDQVLNEVGRLVEKYKD--EEISITICGHSLGAALATLNAvdivangFNRS 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  343 RDVPALSGNISVISFGAPRVGNLAFKEKLNSL-GVKVLRVVNKQDIVPKLPGIvfnkvlnklnpitsrlnwVYRHVGTQL 421
Cdd:PLN02571 256 KSRPNKSCPVTAFVFASPRVGDSDFKKLFSGLkDLRVLRVRNLPDVIPNYPLI------------------GYSDVGEEL 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  422 KLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVASVNKSTDMLLDHLRIPEFWYQVAHKGLIlNKQ 501
Cdd:PLN02571 318 PIDTRKSKYLKSPGNLSTWHNLEAYLHGVAGTQGSKGGFRLEVNRDIALVNKSVDGLKDEYLVPGSWRVQKNKGMV-QQA 396


                 ....
gi 15220732  502 TGRW 505
Cdd:PLN02571 397 DGSW 400
PLN02408 PLN02408
phospholipase A1
 120-466 9.30e-95

phospholipase A1


Pssm-ID: 215228  Cd Length: 365  Bit Score: 292.51  E-value: 9.30e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  120 ELHGSNNWENLLDPLHPWLRREVTKYGEFVESVYDSLDFDPLSEFCGSSRYNRNKLFEELGLTRHGYKVTKYIYAMSRVD 199
Cdd:PLN02408   2 EYQGIRNWDGLLDPLDDNLRGEILRYGDFVEAAYKSFDFDPSSPTYATCRFPKSTLLERSGLPNTGYRLTKHLRATSGIQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  200 VPQWFLSSAlgeTW-SKDSNWMGFVAVSGDRESL-RIGRRDIVVAWRGTVTPTEWFMDLRTSM-----EPFDCEGKHGKT 272
Cdd:PLN02408  82 LPRWIEKAP---SWvATQSSWIGYVAVCQDKEEIaRLGRRDVVIAFRGTATCLEWLENLRATLtrlpnAPTDMNGSGDGS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  273 VVKVQSGFLSIYNSKSELtrynKESASEQTMDEVKRLVNFFKDrgEEVSLTITGHSLGGALALMNAYEAA---RDVPAls 349
Cdd:PLN02408 159 GPMVESGFLSLYTSGTAM----GPSLQEMVREEIARLLQSYGD--EPLSLTITGHSLGAALATLTAYDIKttfKRAPM-- 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  350 gnISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPGIVF---NKVLNKLNPITSRL-----------NWVYR 415
Cdd:PLN02408 231 --VTVISFGGPRVGNRSFRRQLEKQGTKVLRIVNSDDVITKVPGFVIdgeNDVAKKRDVNVAGLpswiqkrvedtQWVYA 308

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 15220732  416 HVGTQLKLDVFSSPYVKRdSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARR 466
Cdd:PLN02408 309 EVGRELRLSSKDSPYLNS-INVATCHDLKTYLHLVNGFVSSTCPFRATAKR 358
PLN02324 PLN02324
triacylglycerol lipase
 112-505 1.34e-94

triacylglycerol lipase


Pssm-ID: 177958  Cd Length: 415  Bit Score: 294.23  E-value: 1.34e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  112 EKISKMWRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVYDSLDFDPLSEFCGSSRYNRNKLFEELGLTRHG---YKV 188
Cdd:PLN02324   3 EGIPKRWKVLSGQNKWKGLLDPLDPDLRRYIIHYGEMSQVGYDAFNWDRKSKYAGDCYYSKNELFARTGFLKANpfrYEV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  189 TKYIYAMSRVDVPQWFLSSALG-ETWSKDSNWMGFVAVSGDRESLRIGRRDIVVAWRGTVTPTEWFMDLRTSMEP----F 263
Cdd:PLN02324  83 TKYIYATASIKLPICFIVKSLSkDASRVQTNWMGYIAVATDQGKAMLGRRDIVVAWRGTLQPYEWANDFDFPLESaisvF 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  264 dcEGKHGKTVVKVQSGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFFKDrgEEVSLTITGHSLGGALALMNAY---- 339
Cdd:PLN02324 163 --PVTDPKDNPRIGSGWLDIYTASDSRSPYDTTSAQEQVQGELKRLLELYKN--EEISITFTGHSLGAVMSVLSAAdlvy 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  340 -EAARDVPALSGN---ISVISFGAPRVGNLAFKEKLNSLG-VKVLRVVNKQDIVPKLPGIVFNKvlnklnpitsrlnwvy 414
Cdd:PLN02324 239 gKKNKINISLQKKqvpITVFAFGSPRIGDHNFKNLVDSLQpLNILRIVNVPDVAPHYPLLLYTE---------------- 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  415 rhVGTQLKLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVASVNKSTDMLLDHLRIPEFWYQVAHK 494
Cdd:PLN02324 303 --IGEVLEINTLNSTYLKRSLNFRNYHNLEAYLHGVAGMQDTQGEFKLEINRDIALVNKGLDALEDKYLVPGHWWVLENK 380

                        410
                 ....*....|.
gi 15220732  495 GLiLNKQTGRW 505
Cdd:PLN02324 381 GM-VQSDDGTW 390
PLN02454 PLN02454
triacylglycerol lipase
 118-518 2.16e-94

triacylglycerol lipase


Pssm-ID: 215249  Cd Length: 414  Bit Score: 293.28  E-value: 2.16e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  118 WRELHGSNNWENLLDPLHPWLRREVTKYGEFVESVYDSLDFDPLSEFCGSSRYNRNKLFEELGLTRHG-YKVTKYIYAMS 196
Cdd:PLN02454   9 WPELLGSANWDGLLDPLDLSLRELILRCGDFCQATYDSFNNDQNSKYCGASRYGKSSFFDKVMLEAASdYEVAAFLYATA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  197 RVDVPQWFLSSALG-ETWSKDSNWMGFVAVSGDRESLRIGRRDIVVAWRGTVTPTEWFMDLR---TSMEPF--------- 263
Cdd:PLN02454  89 RVSLPEAFLLHSMSrESWDRESNWIGYIAVTSDERTKALGRREIYVAWRGTTRNYEWVDVLGaklTSADPLlpgpeqdgv 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  264 -----DCEGKHGKTVVKVQSGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFFKDrgEEVSLTITGHSLGGALALMNA 338
Cdd:PLN02454 169 vsgssSDSDDDDEKGPKVMLGWLTIYTSDDPRSPFTKLSARSQLLAKIKELLERYKD--EKLSIVLTGHSLGASLATLAA 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  339 YEAARDVpaLSGN---ISVISFGAPRVGNLAFKEKLNSL-GVKVLRVVNKQDIVPKLPGIVFNkvlnklnpitsrlnwvY 414
Cdd:PLN02454 247 FDIVENG--VSGAdipVTAIVFGSPQVGNKEFNDRFKEHpNLKILHVRNTIDLIPHYPGGLLG----------------Y 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  415 RHVGTQLKLDVFSSPYVKRDSDLGRAHNLEVYLHVLDGFHRKKSGFRVNARRDVASVNKSTDMLLDHLRIPEFWYQVAHK 494
Cdd:PLN02454 309 VNTGTELVIDTRKSPFLKDSKNPGDWHNLQAMLHVVAGWNGKKGEFELKVKRSLALVNKSCAFLKDECLVPGSWWVEKNK 388

                        410       420
                 ....*....|....*....|....
gi 15220732  495 GLILNkQTGRWVKPVRAPEDIPSP 518
Cdd:PLN02454 389 GMVRG-EDGEWVLAPPAEEDLPVP 411
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 171-451 9.02e-52

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 176.13  E-value: 9.02e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 171 NRNKLFEELGLTRHGYKVTKYIYAMSRVDvPQWFLSSALG----ETWSKDSNWMGFVAVSGDReslrigrRDIVVAWRGT 246
Cdd:cd00519   1 DYEKLKYYAKLAAAAYCVDANILAKAVVF-ADIALLNVFSpdklLKTDKQYDTQGYVAVDHDR-------KTIVIAFRGT 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 247 VTPTEWFMDLRTSMEPFDCEGKHGktvVKVQSGFLSIYNSKSELTRYNKESASEQtmdevkrlvnffkdrGEEVSLTITG 326
Cdd:cd00519  73 VSLADWLTDLDFSPVPLDPPLCSG---GKVHSGFYSAYKSLYNQVLPELKSALKQ---------------YPDYKIIVTG 134

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 327 HSLGGALALMNAYEAARDVPalSGNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPgivfnkvlnklnPI 406
Cdd:cd00519 135 HSLGGALASLLALDLRLRGP--GSDVTVYTFGQPRVGNAAFAEYLESTKGRVYRVVHGNDIVPRLP------------PG 200

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*
gi 15220732 407 TSRLNWVYRHVGTQLKLDvfsspyvkrdsdlgraHNLEVYLHVLD 451
Cdd:cd00519 201 SLTPPEGYTHVGTEVWID----------------HLPYFYIDALC 229
Lipase_3 pfam01764
Lipase (class 3);
240-395 5.12e-47

Lipase (class 3);


Pssm-ID: 396362 [Multi-domain]  Cd Length: 139  Bit Score: 160.12  E-value: 5.12e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732   240 VVAWRGTVTPTEWFMDLRTSMEPFDCEGKHGktvVKVQSGFLSIYnskseltrynkESASEQTMDEVKRLVNFFKDrgee 319
Cdd:pfam01764   1 VVAFRGTNSILDWLTDFDFSLTPFKDFFLGG---GKVHSGFLSAY-----------TSVREQVLAELKRLLEKYPD---- 62

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15220732   320 VSLTITGHSLGGALALMNAYEAARDVPALSGNISVISFGAPRVGNLAFKEKLNSLGVK-VLRVVNKQDIVPKLPGIV 395
Cdd:pfam01764  63 YSIVVTGHSLGGALASLAALDLVENGLRLSSRVTVVTFGQPRVGNLEFAKLHDSQGPKfSYRVVHQRDIVPRLPPIV 139
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
235-448 2.01e-25

Predicted lipase [Lipid transport and metabolism];


Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 105.61  E-value: 2.01e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 235 GRRDIVVAWRGTVTPTEWFMDLRTSMEPFdcegKHGKTVVKVQSGFLSIYNSkseltrynkesASEQTMDEVKRLvnffk 314
Cdd:COG3675  25 SDDEVIVAFRGTESLTDWLTNLNAAQVPY----PFAKTGGKVHRGFYRALQS-----------LRELLEDALRPL----- 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 315 drGEEVSLTITGHSLGGALALMNAYEAARDVPalSGNISVISFGAPRVGNLAFKEKLNSLGVKVLRVVNKQDIVPKLPgi 394
Cdd:COG3675  85 --SPGKRLYVTGHSLGGALATLAAADLERNYI--FPVRGLYTFGQPRVGDRSFAKYYNLHVPNSYRIVNNNDIVPLLP-- 158

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 15220732 395 vfnkvlnklnpitsRLNWVYRHVGTQLKLDVFSSPYVKRDSDLGRAHNLEVYLH 448
Cdd:COG3675 159 --------------PVWMGYDHVGKLLWLDSLRKDMLTDHSMDNYIHHTDLSQL 198
Lipase cd00741
Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and ...
 297-483 2.10e-21

Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238382 [Multi-domain]  Cd Length: 153  Bit Score: 90.64  E-value: 2.10e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 297 SASEQTMDEVKRLVNFFKDRGEEVSLTITGHSLGGALALMNAYEAARDVPalSGNISVISFGAPRVGNLAFKEK--LNSL 374
Cdd:cd00741   5 KAARSLANLVLPLLKSALAQYPDYKIHVTGHSLGGALAGLAGLDLRGRGL--GRLVRVYTFGPPRVGNAAFAEDrlDPSD 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 375 GVKVLRVVNKQDIVPKLPGIvfnkvlnklnpitsrlNWVYRHVGTqlkldvfsspyvkrdsdlgrahnlEVYLHVLDGFH 454
Cdd:cd00741  83 ALFVDRIVNDNDIVPRLPPG----------------GEGYPHGGA------------------------EFYINGGKSQP 122

                       170       180
                ....*....|....*....|....*....
gi 15220732 455 RKKSGFRVNARRDVASVNKSTDMLLDHLR 483
Cdd:cd00741 123 GCCKNVLEAVDIDFGNIGLSGNGLCDHLR 151
PLN00413 PLN00413
triacylglycerol lipase
 204-392 1.61e-12

triacylglycerol lipase


Pssm-ID: 165792  Cd Length: 479  Bit Score: 69.66  E-value: 1.61e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  204 FLSSALGETWSKDsnWMGFVAVSGDRESLR----IGRRD-------IVVAWRGT--VTPTEWFMDLrtsmepfDCEGKHG 270
Cdd:PLN00413 158 FIRSVLHDHWKMD--LLGFYSCPNDFDKQRstevIVIKDtkddpnlIIVSFRGTdpFDADDWCTDL-------DLSWHEV 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  271 KTVVKVQSGFLSIYNSKSEltRYNKESASEQTMDE--------VKRLVNFFKDRGEEVSLTITGHSLGGALA-LMNAYEA 341
Cdd:PLN00413 229 KNVGKIHGGFMKALGLPKE--GWPEEINLDETQNAtsllayytILRHLKEIFDQNPTSKFILSGHSLGGALAiLFTAVLI 306

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15220732  342 ARDVPALSGNIS-VISFGAPRVGNLAF----KEKLNSLGVKVLRVVNKQDIVPKLP 392
Cdd:PLN00413 307 MHDEEEMLERLEgVYTFGQPRVGDEDFgifmKDKLKEFDVKYERYVYCNDMVPRLP 362
CVT17 COG5153
Putative lipase ATG15 (essential for vacuolar disintegration of autophagic bodies) ...
 238-389 4.92e-12

Putative lipase ATG15 (essential for vacuolar disintegration of autophagic bodies) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444061  Cd Length: 405  Bit Score: 67.73  E-value: 4.92e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732 238 DIVVAWRGTVTPTEWFMDLRTSMEPFDCEGKH--GKTVVKVQSGFlsiynSKSELTRYNKESASEQTMdeVKRLVNFFKD 315
Cdd:COG5153  46 DTIIAFRGTQGKPDWKTDINASLHDYDEKNKEadEKLPLQVHEGF-----EQYAAQVMDLDYDGAEEL--AAEVKKQYPD 118

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15220732 316 RgeevSLTITGHSLGGALAlmnayeaarDVPALSGNISVISFGAPRVGNLAFKEKLNSlGVKVLRVVNKQDIVP 389
Cdd:COG5153 119 A----ELSLTGHSLGGALA---------SLVAVATGLSKVTFAAPGSGNHALADDLGK-RIDAGEFVKSLDAVA 178
PLN02934 PLN02934
triacylglycerol lipase
 278-392 4.11e-07

triacylglycerol lipase


Pssm-ID: 215504  Cd Length: 515  Bit Score: 52.48  E-value: 4.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  278 SGFLSIYNSKSELTRYNKESASEQTMDEVKRLVNFFKDrgeeVSLTITGHSLGGALALM--NAYEAARDVPALSGNISVI 355
Cdd:PLN02934 283 TSELKEEESKKNLLEMVERSAYYAVRSKLKSLLKEHKN----AKFVVTGHSLGGALAILfpTVLVLQEETEVMKRLLGVY 358

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 15220732  356 SFGAPRVGNLAF----KEKLNSLGVKVLRVVNKQDIVPKLP 392
Cdd:PLN02934 359 TFGQPRIGNRQLgkfmEAQLNYPVPRYFRVVYCNDLVPRLP 399
PLN02162 PLN02162
triacylglycerol lipase
 239-392 2.03e-06

triacylglycerol lipase


Pssm-ID: 177821  Cd Length: 475  Bit Score: 50.43  E-value: 2.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  239 IVVAWRGT--VTPTEWFMDLRTSMEPFdcegkhgKTVVKVQSGFLSIYNSKSElTRYNKESAS---EQTMDEVKRLVNFF 313
Cdd:PLN02162 200 IVVSFRGTepFEAADWCTDLDLSWYEL-------KNVGKVHAGFSRALGLQKD-GGWPKENISllhQYAYYTIRQMLRDK 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220732  314 KDRGEEVSLTITGHSLGGAL-ALMNAYEAARDVPALSGNIS-VISFGAPRVGNLAFKEKLNSL----GVKVLRVVNKQDI 387
Cdd:PLN02162 272 LARNKNLKYILTGHSLGGALaALFPAILAIHGEDELLDKLEgIYTFGQPRVGDEDFGEFMKGVvkkhGIEYERFVYNNDV 351


                 ....*
gi 15220732  388 VPKLP 392
Cdd:PLN02162 352 VPRVP 356
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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