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Conserved domains on  [gi|15223004|ref|NP_172849|]
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WRKY DNA-binding protein 4 [Arabidopsis thaliana]

Protein Classification

WRKY transcription factor( domain architecture ID 10654900)

WRKY transcription factor is predominantly found in plants and is involved in multiple aspects of plant growth, development and stress response

CATH:  2.20.25.80
Gene Ontology:  GO:0003700
PubMed:  20304701
SCOP:  4003937

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 408-465 5.54e-36

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


:

Pssm-ID: 214815  Cd Length: 59  Bit Score: 127.60  E-value: 5.54e-36
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 15223004    408 LDDGYRWRKYGQKVVKGNPYPRSYYKCT-TPGCGVRKHVERAATDPKAVVTTYEGKHNH 465
Cdd:smart00774   1 LDDGYQWRKYGQKVIKGSPYPRSYYRCTyTQGCPAKKQVQRSDDDPSVVEVTYEGEHTH 59
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 229-284 6.01e-35

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


:

Pssm-ID: 214815  Cd Length: 59  Bit Score: 124.91  E-value: 6.01e-35
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 15223004    229 DDGYNWRKYGQKQVKGSEFPRSYYKCTN-PGCPVKKKVERSL-DGQVTEIIYKGQHNH 284
Cdd:smart00774   2 DDGYQWRKYGQKVIKGSPYPRSYYRCTYtQGCPAKKQVQRSDdDPSVVEVTYEGEHTH 59
 
Name Accession Description Interval E-value
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 408-465 5.54e-36

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


Pssm-ID: 214815  Cd Length: 59  Bit Score: 127.60  E-value: 5.54e-36
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 15223004    408 LDDGYRWRKYGQKVVKGNPYPRSYYKCT-TPGCGVRKHVERAATDPKAVVTTYEGKHNH 465
Cdd:smart00774   1 LDDGYQWRKYGQKVIKGSPYPRSYYRCTyTQGCPAKKQVQRSDDDPSVVEVTYEGEHTH 59
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 229-284 6.01e-35

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


Pssm-ID: 214815  Cd Length: 59  Bit Score: 124.91  E-value: 6.01e-35
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 15223004    229 DDGYNWRKYGQKQVKGSEFPRSYYKCTN-PGCPVKKKVERSL-DGQVTEIIYKGQHNH 284
Cdd:smart00774   2 DDGYQWRKYGQKVIKGSPYPRSYYRCTYtQGCPAKKQVQRSDdDPSVVEVTYEGEHTH 59
WRKY pfam03106
WRKY DNA -binding domain;
410-465 3.13e-34

WRKY DNA -binding domain;


Pssm-ID: 460808  Cd Length: 57  Bit Score: 122.97  E-value: 3.13e-34
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15223004   410 DGYRWRKYGQKVVKGNPYPRSYYKCT-TPGCGVRKHVERAATDPKAVVTTYEGKHNH 465
Cdd:pfam03106   1 DGYSWRKYGQKQIKGSKFPRSYYRCThKPGCPAKKQVQRSPDDPSIFEVTYEGEHTH 57
WRKY pfam03106
WRKY DNA -binding domain;
230-284 3.69e-34

WRKY DNA -binding domain;


Pssm-ID: 460808  Cd Length: 57  Bit Score: 122.58  E-value: 3.69e-34
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15223004   230 DGYNWRKYGQKQVKGSEFPRSYYKCTN-PGCPVKKKVERSL-DGQVTEIIYKGQHNH 284
Cdd:pfam03106   1 DGYSWRKYGQKQIKGSKFPRSYYRCTHkPGCPAKKQVQRSPdDPSIFEVTYEGEHTH 57
 
Name Accession Description Interval E-value
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 408-465 5.54e-36

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


Pssm-ID: 214815  Cd Length: 59  Bit Score: 127.60  E-value: 5.54e-36
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 15223004    408 LDDGYRWRKYGQKVVKGNPYPRSYYKCT-TPGCGVRKHVERAATDPKAVVTTYEGKHNH 465
Cdd:smart00774   1 LDDGYQWRKYGQKVIKGSPYPRSYYRCTyTQGCPAKKQVQRSDDDPSVVEVTYEGEHTH 59
WRKY smart00774
DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a ...
 229-284 6.01e-35

DNA binding domain; The WRKY domain is a DNA binding domain found in one or two copies in a superfamily of plant transcription factors. These transcription factors are involved in the regulation of various physiological programs that are unique to plants, including pathogen defense, senescence and trichome development. The domain is a 60 amino acid region that is defined by the conserved amino acid sequence WRKYGQK at its N-terminal end, together with a novel zinc-finger-like motif. It binds specifically to the DNA sequence motif (T)(T)TGAC(C/T), which is known as the W box. The invariant TGAC core is essential for function and WRKY binding.


Pssm-ID: 214815  Cd Length: 59  Bit Score: 124.91  E-value: 6.01e-35
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 15223004    229 DDGYNWRKYGQKQVKGSEFPRSYYKCTN-PGCPVKKKVERSL-DGQVTEIIYKGQHNH 284
Cdd:smart00774   2 DDGYQWRKYGQKVIKGSPYPRSYYRCTYtQGCPAKKQVQRSDdDPSVVEVTYEGEHTH 59
WRKY pfam03106
WRKY DNA -binding domain;
410-465 3.13e-34

WRKY DNA -binding domain;


Pssm-ID: 460808  Cd Length: 57  Bit Score: 122.97  E-value: 3.13e-34
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15223004   410 DGYRWRKYGQKVVKGNPYPRSYYKCT-TPGCGVRKHVERAATDPKAVVTTYEGKHNH 465
Cdd:pfam03106   1 DGYSWRKYGQKQIKGSKFPRSYYRCThKPGCPAKKQVQRSPDDPSIFEVTYEGEHTH 57
WRKY pfam03106
WRKY DNA -binding domain;
230-284 3.69e-34

WRKY DNA -binding domain;


Pssm-ID: 460808  Cd Length: 57  Bit Score: 122.58  E-value: 3.69e-34
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15223004   230 DGYNWRKYGQKQVKGSEFPRSYYKCTN-PGCPVKKKVERSL-DGQVTEIIYKGQHNH 284
Cdd:pfam03106   1 DGYSWRKYGQKQIKGSKFPRSYYRCTHkPGCPAKKQVQRSPdDPSIFEVTYEGEHTH 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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