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Conserved domains on  [gi|165905593|ref|NP_080281|]
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cilia- and flagella-associated protein 418 [Mus musculus]

Protein Classification

RMP domain-containing protein( domain architecture ID 10633200)

RMP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RMP pfam14996
Retinal Maintenance; RMP is encoded for by a gene, C8orf37. Mutations in the gene cause two ...
 64-209 4.59e-82

Retinal Maintenance; RMP is encoded for by a gene, C8orf37. Mutations in the gene cause two types of retinal dystrophies: cone-rod dystrophy type 16 (CORD16) and retinitis pigmentosa type 64 (RP64). CORD16 affects the cone receptors which detect red, green or blue wavelengths of light and RP64 affects the cone receptors first and then the rod receptors. Both of these affect the photo-receptors in the eye leading to colour blindness or blindness respectively.


:

Pssm-ID: 464431  Cd Length: 154  Bit Score: 240.74  E-value: 4.59e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 165905593   64 LDSLINEIFEEPDFDRKSF--------QKFKSKSSSNTCVRAPMQGVSKSCSPVYLSGSAIPCGIGTNTSQRACDRLRCV 135
Cdd:pfam14996   1 LDDLLDEICEEDDKDPKGKpkpisprpASPGKSSDASKSSRASSQAGSKRCCPVYLGGSSVPNGIGTSTSQRACDQLRCT 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 165905593  136 ACDFRIVSYNDYMWDKSCDYLFFRNNMPEFHKLKTKLIEKKGARAYACQCSWRTVEELTDLQTDHQLRWVCGKH 209
Cdd:pfam14996  81 ACDFRVVSFDDYKWDQSCDYLFFRNNMPDFEKLRAKLKKKPGSRAYACQCSWRSVDELTDLRNDPQLRWVCGKH 154
 
Name Accession Description Interval E-value
RMP pfam14996
Retinal Maintenance; RMP is encoded for by a gene, C8orf37. Mutations in the gene cause two ...
 64-209 4.59e-82

Retinal Maintenance; RMP is encoded for by a gene, C8orf37. Mutations in the gene cause two types of retinal dystrophies: cone-rod dystrophy type 16 (CORD16) and retinitis pigmentosa type 64 (RP64). CORD16 affects the cone receptors which detect red, green or blue wavelengths of light and RP64 affects the cone receptors first and then the rod receptors. Both of these affect the photo-receptors in the eye leading to colour blindness or blindness respectively.


Pssm-ID: 464431  Cd Length: 154  Bit Score: 240.74  E-value: 4.59e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 165905593   64 LDSLINEIFEEPDFDRKSF--------QKFKSKSSSNTCVRAPMQGVSKSCSPVYLSGSAIPCGIGTNTSQRACDRLRCV 135
Cdd:pfam14996   1 LDDLLDEICEEDDKDPKGKpkpisprpASPGKSSDASKSSRASSQAGSKRCCPVYLGGSSVPNGIGTSTSQRACDQLRCT 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 165905593  136 ACDFRIVSYNDYMWDKSCDYLFFRNNMPEFHKLKTKLIEKKGARAYACQCSWRTVEELTDLQTDHQLRWVCGKH 209
Cdd:pfam14996  81 ACDFRVVSFDDYKWDQSCDYLFFRNNMPDFEKLRAKLKKKPGSRAYACQCSWRSVDELTDLRNDPQLRWVCGKH 154
 
Name Accession Description Interval E-value
RMP pfam14996
Retinal Maintenance; RMP is encoded for by a gene, C8orf37. Mutations in the gene cause two ...
 64-209 4.59e-82

Retinal Maintenance; RMP is encoded for by a gene, C8orf37. Mutations in the gene cause two types of retinal dystrophies: cone-rod dystrophy type 16 (CORD16) and retinitis pigmentosa type 64 (RP64). CORD16 affects the cone receptors which detect red, green or blue wavelengths of light and RP64 affects the cone receptors first and then the rod receptors. Both of these affect the photo-receptors in the eye leading to colour blindness or blindness respectively.


Pssm-ID: 464431  Cd Length: 154  Bit Score: 240.74  E-value: 4.59e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 165905593   64 LDSLINEIFEEPDFDRKSF--------QKFKSKSSSNTCVRAPMQGVSKSCSPVYLSGSAIPCGIGTNTSQRACDRLRCV 135
Cdd:pfam14996   1 LDDLLDEICEEDDKDPKGKpkpisprpASPGKSSDASKSSRASSQAGSKRCCPVYLGGSSVPNGIGTSTSQRACDQLRCT 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 165905593  136 ACDFRIVSYNDYMWDKSCDYLFFRNNMPEFHKLKTKLIEKKGARAYACQCSWRTVEELTDLQTDHQLRWVCGKH 209
Cdd:pfam14996  81 ACDFRVVSFDDYKWDQSCDYLFFRNNMPDFEKLRAKLKKKPGSRAYACQCSWRSVDELTDLRNDPQLRWVCGKH 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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