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Conserved domains on  [gi|31377618|ref|NP_061949|]
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UDP-glucuronosyltransferase 1A8 precursor [Homo sapiens]

Protein Classification

UDP-glycosyltransferase family protein( domain architecture ID 11989770)

UDP-glycosyltransferase family protein similar to UDP-glucuronosyltransferase (UDPGT), which is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds

EC:  2.4.-.-
Gene Ontology:  GO:0008194|GO:0006486
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
26-521 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


:

Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 853.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618    26 GKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLG--KSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVR 103
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   104 SLFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEGA-Q 182
Cdd:pfam00201  81 GTVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSgG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   183 CPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYP 262
Cdd:pfam00201 161 LPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEFP 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   263 KPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNL 342
Cdd:pfam00201 241 RPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPSTL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   343 ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 422
Cdd:pfam00201 321 GNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLLN 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   423 ALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFI 502
Cdd:pfam00201 401 ALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAFI 480

                         490
                  ....*....|....*....
gi 31377618   503 TFKCCAYGYRKCLGKKGRV 521
Cdd:pfam00201 481 TFKCCLFGYRKFVGKKKRV 499
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
26-521 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 853.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618    26 GKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLG--KSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVR 103
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   104 SLFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEGA-Q 182
Cdd:pfam00201  81 GTVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSgG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   183 CPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYP 262
Cdd:pfam00201 161 LPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEFP 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   263 KPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNL 342
Cdd:pfam00201 241 RPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPSTL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   343 ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 422
Cdd:pfam00201 321 GNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLLN 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   423 ALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFI 502
Cdd:pfam00201 401 ALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAFI 480

                         490
                  ....*....|....*....
gi 31377618   503 TFKCCAYGYRKCLGKKGRV 521
Cdd:pfam00201 481 TFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 28-443 4.19e-77

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 248.23  E-value: 4.19e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  28 LLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEvswqlgkslnctvktYSTSYTLEDLDREFMDFADAQWKAQVRSLFS 107
Cdd:cd03784   4 LFVPFPGQGHVNPMLPLAKALAARGHEVTVATPP---------------FNFADLVEAAGLTFVPVGDDPDELELDSETN 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 108 LFLSSSNGFFNLFFSHCRSLFNDrkLVEYLKESS-FDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEegaqCPAP 186
Cdd:cd03784  69 LGPDSLLELLRRLLKAADELLDD--LLAALRSSWkPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSA----YLHP 142

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 187 LSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIaseilqTPVTAYDLYSHTSIWLlrtdfvldYPKPVM 266
Cdd:cd03784 143 FGVLNLLLSSLLEPELFLDPLLEVLDRLRERLGLPPFSLVLLLL------RLVPPLYVIGPTFPSL--------PPDRPR 208

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 267 PNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS---NLA 343
Cdd:cd03784 209 LPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRLP 288

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 344 NNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENA 423
Cdd:cd03784 289 DNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAKA 368

                       410       420
                ....*....|....*....|
gi 31377618 424 LKAVINDKSYKENIMRLSSL 443
Cdd:cd03784 369 VREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 258-504 4.77e-43

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 160.12  E-value: 4.77e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  258 VLDYPKPVMPNMIFIGGINCHQGKPLPM--EFEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQT 329
Cdd:PHA03392 256 VFDNNRPVPPSVQYLGGLHLHKKPPQPLddYLEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYN 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  330 VLWRYTGT-RPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 408
Cdd:PHA03392 331 VLWKYDGEvEAINLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGR 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  409 TLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsld 487
Cdd:PHA03392 411 ALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY---- 486

                        250
                 ....*....|....*..
gi 31377618  488 VIGFLLAVVLTVAFITF 504
Cdd:PHA03392 487 FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
259-441 2.04e-31

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 122.27  E-value: 2.04e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 259 LDYPKPVMP-NMIFIGGINCHQGKPLPmefeAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGT 337
Cdd:COG1819  85 LEYPRPPDPaNVRFVGPLLPDGPAELP----PWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGL 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 338 RPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE 414
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237

                       170       180
                ....*....|....*....|....*..
gi 31377618 415 MTSEDLENALKAVINDKSYKENIMRLS 441
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 297-440 5.07e-19

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 88.97  E-value: 5.07e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   297 HGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGS 372
Cdd:TIGR01426 225 RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNVEVRQWVPQLEILKK--ADAFITHGGM 301

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 31377618   373 HGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRL 440
Cdd:TIGR01426 302 NSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAERLRKM 369
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
26-521 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 853.24  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618    26 GKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLG--KSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVR 103
Cdd:pfam00201   1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGpgKPSNLKFETYPTSATKEELENPFPKRQMQWFEEASF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   104 SLFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEGA-Q 182
Cdd:pfam00201  81 GTVWSYFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKVSgG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   183 CPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYP 262
Cdd:pfam00201 161 LPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLGRPVTLPELMSKASVWLIRSYWDLEFP 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   263 KPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNL 342
Cdd:pfam00201 241 RPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPSTL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   343 ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 422
Cdd:pfam00201 321 GNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLLN 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   423 ALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFI 502
Cdd:pfam00201 401 ALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAFI 480

                         490
                  ....*....|....*....
gi 31377618   503 TFKCCAYGYRKCLGKKGRV 521
Cdd:pfam00201 481 TFKCCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 28-443 4.19e-77

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 248.23  E-value: 4.19e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  28 LLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEvswqlgkslnctvktYSTSYTLEDLDREFMDFADAQWKAQVRSLFS 107
Cdd:cd03784   4 LFVPFPGQGHVNPMLPLAKALAARGHEVTVATPP---------------FNFADLVEAAGLTFVPVGDDPDELELDSETN 68

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 108 LFLSSSNGFFNLFFSHCRSLFNDrkLVEYLKESS-FDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEegaqCPAP 186
Cdd:cd03784  69 LGPDSLLELLRRLLKAADELLDD--LLAALRSSWkPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSA----YLHP 142

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 187 LSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIaseilqTPVTAYDLYSHTSIWLlrtdfvldYPKPVM 266
Cdd:cd03784 143 FGVLNLLLSSLLEPELFLDPLLEVLDRLRERLGLPPFSLVLLLL------RLVPPLYVIGPTFPSL--------PPDRPR 208

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 267 PNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS---NLA 343
Cdd:cd03784 209 LPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRLP 288

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 344 NNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENA 423
Cdd:cd03784 289 DNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAKA 368

                       410       420
                ....*....|....*....|
gi 31377618 424 LKAVINDKSYKENIMRLSSL 443
Cdd:cd03784 369 VREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 258-504 4.77e-43

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 160.12  E-value: 4.77e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  258 VLDYPKPVMPNMIFIGGINCHQGKPLPM--EFEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQT 329
Cdd:PHA03392 256 VFDNNRPVPPSVQYLGGLHLHKKPPQPLddYLEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYN 330

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  330 VLWRYTGT-RPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 408
Cdd:PHA03392 331 VLWKYDGEvEAINLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGR 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  409 TLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsld 487
Cdd:PHA03392 411 ALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY---- 486

                        250
                 ....*....|....*..
gi 31377618  488 VIGFLLAVVLTVAFITF 504
Cdd:PHA03392 487 FMSYILVPLVTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
259-441 2.04e-31

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 122.27  E-value: 2.04e-31
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 259 LDYPKPVMP-NMIFIGGINCHQGKPLPmefeAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGT 337
Cdd:COG1819  85 LEYPRPPDPaNVRFVGPLLPDGPAELP----PWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGL 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 338 RPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE 414
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237

                       170       180
                ....*....|....*....|....*..
gi 31377618 415 MTSEDLENALKAVINDKSYKENIMRLS 441
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 297-440 5.07e-19

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 88.97  E-value: 5.07e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   297 HGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGS 372
Cdd:TIGR01426 225 RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNVEVRQWVPQLEILKK--ADAFITHGGM 301

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 31377618   373 HGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRL 440
Cdd:TIGR01426 302 NSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAERLRKM 369
PLN02410 PLN02410
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 290-402 1.63e-12

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 178032 [Multi-domain]  Cd Length: 451  Bit Score: 69.30  E-value: 1.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  290 YINASGEHGIVVFSLGSM-VSEIPEkkAMAIADALGKIPQTVLWRytgTRPSNLANNT-----------------ILVKW 351
Cdd:PLN02410 257 WLNKQKKNSVIFVSLGSLaLMEINE--VMETASGLDSSNQQFLWV---IRPGSVRGSEwieslpkefskiisgrgYIVKW 331

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 31377618  352 LPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME 402
Cdd:PLN02410 332 APQKEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLE 382
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 253-432 4.18e-12

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 68.16  E-value: 4.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  253 LRTDFVLDYPK-------PVMPNMIFIGGINchqGKPLPME-----FEAYINASGEHGIVVFSLGSMVsEIPEKKAMAIA 320
Cdd:PLN02152 208 LEPEFLTAIPNiemvavgPLLPAEIFTGSES---GKDLSVRdqsssYTLWLDSKTESSVIYVSFGTMV-ELSKKQIEELA 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  321 DAL--GKIP-------------------QTVLWRYTGTRpSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESI 379
Cdd:PLN02152 284 RALieGKRPflwvitdklnreakiegeeETEIEKIAGFR-HELEEVGMIVSWCSQIEVLRHRAVGCFVTHCGWSSSLESL 362

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 31377618  380 CNGVPMVMMPLFGDQMDNAKRME---TKGAGVTLNVLEMTSE-DLENALKAVINDKS 432
Cdd:PLN02152 363 VLGVPVVAFPMWSDQPANAKLLEeiwKTGVRVRENSEGLVERgEIRRCLEAVMEEKS 419
PLN03015 PLN03015
UDP-glucosyl transferase
 264-418 1.57e-09

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 60.09  E-value: 1.57e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  264 PVMPnmifIGGI---NCHQGKPLPMeFEaYINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLW------RY 334
Cdd:PLN03015 237 PVYP----IGPIvrtNVHVEKRNSI-FE-WLDKQGERSVVYVCLGSG-GTLTFEQTVELAWGLELSGQRFVWvlrrpaSY 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  335 TG-----------TRPSNLANNT-----ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 398
Cdd:PLN03015 310 LGasssdddqvsaSLPEGFLDRTrgvglVVTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNA 389

                        170       180
                 ....*....|....*....|
gi 31377618  399 KrMETKGAGVTLNVLEMTSE 418
Cdd:PLN03015 390 T-LLTEEIGVAVRTSELPSE 408
PLN02210 PLN02210
UDP-glucosyl transferase
 290-427 1.93e-09

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 59.66  E-value: 1.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  290 YINASGEHGIVVFSLGSMVSEIpEKKAMAIADALGKIPQTVLWRytgTRPSNLANNT------------ILVKWLPQNDL 357
Cdd:PLN02210 262 WLDKQARSSVVYISFGSMLESL-ENQVETIAKALKNRGVPFLWV---IRPKEKAQNVqvlqemvkegqgVVLEWSPQEKI 337

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 31377618  358 LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVL----EMTSEDLENALKAV 427
Cdd:PLN02210 338 LSHMAISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPIDARLLvDVFGIGVRMRNDavdgELKVEEVERCIEAV 412
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 290-443 5.01e-09

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 58.50  E-value: 5.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  290 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIpqTVLWRYTGTRPSNL---------ANNTILVKWLPQNDLLGH 360
Cdd:PLN02173 257 WLDKRPQGSVVYIAFGSM-AKLSSEQMEEIASAISNF--SYLWVVRASEESKLppgfletvdKDKSLVLKWSPQLQVLSN 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  361 PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME-TKGAGVTLNVLEMTS----EDLENALKAVIN---DKS 432
Cdd:PLN02173 334 KAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQdVWKVGVRVKAEKESGiakrEEIEFSIKEVMEgekSKE 413

                        170
                 ....*....|.
gi 31377618  433 YKENIMRLSSL 443
Cdd:PLN02173 414 MKENAGKWRDL 424
PLN02555 PLN02555
limonoid glucosyltransferase
 348-439 5.54e-09

limonoid glucosyltransferase


Pssm-ID: 178170 [Multi-domain]  Cd Length: 480  Bit Score: 58.27  E-value: 5.54e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  348 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL------NVLEMTSEDL 420
Cdd:PLN02555 341 IVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYLvDVFKTGVRLcrgeaeNKLITREEVA 420

                         90       100
                 ....*....|....*....|.
gi 31377618  421 ENALKAVINDKS--YKENIMR 439
Cdd:PLN02555 421 ECLLEATVGEKAaeLKQNALK 441
PLN00164 PLN00164
glucosyltransferase; Provisional
 350-398 1.40e-08

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 56.99  E-value: 1.40e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 31377618  350 KWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 398
Cdd:PLN00164 345 TWAPQKEILAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNA 393
PLN02534 PLN02534
UDP-glycosyltransferase
 347-412 1.50e-08

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 57.18  E-value: 1.50e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 31377618  347 ILVK-WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNV 412
Cdd:PLN02534 346 LLIKgWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQFLNEKLIvEVLRIGVRVGV 413
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 351-398 2.44e-08

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 56.53  E-value: 2.44e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 31377618  351 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 398
Cdd:PLN02992 345 WAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNA 392
PLN03004 PLN03004
UDP-glycosyltransferase
 290-442 3.57e-08

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 55.85  E-value: 3.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  290 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLWryTGTRPSNLANNTILVK------------------- 350
Cdd:PLN03004 263 WLDSQPEKSVVFLCFGSL-GLFSKEQVIEIAVGLEKSGQRFLW--VVRNPPELEKTELDLKsllpegflsrtedkgmvvk 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  351 -WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLE---MTSEDLENALK 425
Cdd:PLN03004 340 sWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMIvDEIKIAISMNESEtgfVSSTEVEKRVQ 419

                        170
                 ....*....|....*..
gi 31377618  426 AVINDKSYKENIMRLSS 442
Cdd:PLN03004 420 EIIGECPVRERTMAMKN 436
PLN02167 PLN02167
UDP-glycosyltransferase family protein
 260-401 3.59e-08

UDP-glycosyltransferase family protein


Pssm-ID: 215112 [Multi-domain]  Cd Length: 475  Bit Score: 55.96  E-value: 3.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  260 DYPkPVMPnmifIGGINCHQGKPLPMEFEA-------YINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW 332
Cdd:PLN02167 241 NYP-PVYP----VGPILSLKDRTSPNLDSSdrdrimrWLDDQPESSVVFLCFGSLGS-LPAPQIKEIAQALELVGCRFLW 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  333 --RYTGTR--------PSNLANNT----ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 398
Cdd:PLN02167 315 siRTNPAEyaspyeplPEGFMDRVmgrgLVCGWAPQVEILAHKAIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQLNA 394


                 ...
gi 31377618  399 KRM 401
Cdd:PLN02167 395 FTM 397
PLN02562 PLN02562
UDP-glycosyltransferase
 299-440 2.22e-07

UDP-glycosyltransferase


Pssm-ID: 215305  Cd Length: 448  Bit Score: 53.35  E-value: 2.22e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  299 IVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYT-----GTRPS---NLANNTILVKWLPQNDLLGHPMTRAFITHA 370
Cdd:PLN02562 275 VIYISFGSWVSPIGESNVRTLALALEASGRPFIWVLNpvwreGLPPGyveRVSKQGKVVSWAPQLEVLKHQAVGCYLTHC 354

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 31377618  371 GSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNvlEMTSEDLENALKAVINDKSYKENIMRL 440
Cdd:PLN02562 355 GWNSTMEAIQCQKRLLCYPVAGDQFVNCAYIvDVWKIGVRIS--GFGQKEVEEGLRKVMEDSGMGERLMKL 423
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 348-441 5.87e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 52.10  E-value: 5.87e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  348 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL-----------NVLEM 415
Cdd:PLN02554 346 VIGWAPQVAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEMvEELGLAVEIrkywrgdllagEMETV 425

                         90       100
                 ....*....|....*....|....*..
gi 31377618  416 TSEDLENALKAVI-NDKSYKENIMRLS 441
Cdd:PLN02554 426 TAEEIERGIRCLMeQDSDVRKRVKEMS 452
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 240-399 1.41e-06

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 50.78  E-value: 1.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  240 TAYDLYSHtSIWLLRTDFvlDYP----KPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSeIPEKK 315
Cdd:PLN02448 216 SFYELEAQ-AIDALKSKF--PFPvypiGPSIPYMELKDNSSSSNNEDNEPDYFQWLDSQPEGSVLYVSLGSFLS-VSSAQ 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  316 AMAIADALGKIPQTVLW---RYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFG 392
Cdd:PLN02448 292 MDEIAAGLRDSGVRFLWvarGEASRLKEICGDMGLVVPWCDQLKVLCHSSVGGFWTHCGWNSTLEAVFAGVPMLTFPLFW 371


                 ....*..
gi 31377618  393 DQMDNAK 399
Cdd:PLN02448 372 DQPLNSK 378
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 347-398 4.69e-06

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 49.10  E-value: 4.69e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 31377618  347 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 398
Cdd:PLN02863 346 VIRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQFVNA 397
PLN02207 PLN02207
UDP-glycosyltransferase
 267-401 5.41e-06

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 48.88  E-value: 5.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  267 PNMIFIGGINCHQGKPLPM-------EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLWRYTGTRP 339
Cdd:PLN02207 238 PSVYAVGPIFDLKAQPHPEqdlarrdELMKWLDDQPEASVVFLCFGSMGR-LRGPLVKEIAHGLELCQYRFLWSLRTEEV 316

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 31377618  340 SN-----------LANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 401
Cdd:PLN02207 317 TNddllpegfldrVSGRGMICGWSPQVEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNAFLM 389
PLN02208 PLN02208
glycosyltransferase family protein
 351-432 1.23e-05

glycosyltransferase family protein


Pssm-ID: 177858  Cd Length: 442  Bit Score: 47.70  E-value: 1.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  351 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALK 425
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQV-LFTRLMTEEFEVSVEVSRektgwFSKESLSNAIK 396


                 ....*..
gi 31377618  426 AVINDKS 432
Cdd:PLN02208 397 SVMDKDS 403
PLN03007 PLN03007
UDP-glucosyltransferase family protein
 299-443 2.64e-05

UDP-glucosyltransferase family protein


Pssm-ID: 178584 [Multi-domain]  Cd Length: 482  Bit Score: 46.78  E-value: 2.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  299 IVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW--RYTGTRPSN------------LANNTILVKWLPQNDLLGHPMTR 364
Cdd:PLN03007 287 VIYLSFGSVAS-FKNEQLFEIAAGLEGSGQNFIWvvRKNENQGEKeewlpegfeertKGKGLIIRGWAPQVLILDHQATG 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  365 AFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLEM--------TSEDLENALKAVINDKSYKE 435
Cdd:PLN03007 366 GFVTHCGWNSLLEGVAAGLPMVTWPVGAEQFYNEKLVtQVLRTGVSVGAKKLvkvkgdfiSREKVEKAVREVIVGEEAEE 445


                 ....*...
gi 31377618  436 NIMRLSSL 443
Cdd:PLN03007 446 RRLRAKKL 453
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 367-447 2.87e-05

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 44.63  E-value: 2.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618   367 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSS 442
Cdd:pfam04101  76 ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNPLRLAEMAKASK 155


                  ....*
gi 31377618   443 LHKDR 447
Cdd:pfam04101 156 ASGFK 160
PLN00414 PLN00414
glycosyltransferase family protein
 298-462 5.76e-05

glycosyltransferase family protein


Pssm-ID: 177807 [Multi-domain]  Cd Length: 446  Bit Score: 45.78  E-value: 5.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  298 GIVVFSLGSMVSEIPEKKAMAIADALgkiPQTVLWRYTGtrpsnlaNNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYE 377
Cdd:PLN00414 276 GMELTGLPFLIAVMPPKGSSTVQEAL---PEGFEERVKG-------RGIVWEGWVEQPLILSHPSVGCFVNHCGFGSMWE 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  378 SICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALKAVINDKSYKENIMRLSSLH-KDRPVEP 451
Cdd:PLN00414 346 SLVSDCQIVFIPQLADQV-LITRLLTEELEVSVKVQRedsgwFSKESLRDTVKSVMDKDSEIGNLVKRNHKKlKETLVSP 424

                        170
                 ....*....|.
gi 31377618  452 LDLAVFWVEFV 462
Cdd:PLN00414 425 GLLSGYADKFV 435
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 367-441 8.34e-05

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 44.90  E-value: 8.34e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 367 ITHAGSHGVYESICNGVPMVMMPLF----GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 438
Cdd:cd03785 257 ISRAGASTIAELTAAGKPAILIPYPyaadDHQEANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDperlKKMAEAAK 336


                ...
gi 31377618 439 RLS 441
Cdd:cd03785 337 KLA 339
MurG COG0707
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ...
 367-441 1.83e-04

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440471 [Multi-domain]  Cd Length: 363  Bit Score: 43.96  E-value: 1.83e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 367 ITHAGSHGVYESICNGVPMVMMPL-F---GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 438
Cdd:COG0707 263 ISRAGASTVAELAALGKPAILVPLpHaadDHQTKNARALVEAGAAVLIPQSELTPEKLAEALEELLEDperlAKMAEAAR 342


                ...
gi 31377618 439 RLS 441
Cdd:COG0707 343 ALA 345
PLN02764 PLN02764
glycosyltransferase family protein
 351-439 2.37e-04

glycosyltransferase family protein


Pssm-ID: 178364  Cd Length: 453  Bit Score: 43.51  E-value: 2.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618  351 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKgAGVTLNVLE-----MTSEDLENALK 425
Cdd:PLN02764 324 WVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIVLVPQLGDQVLNTRLLSDE-LKVSVEVAReetgwFSKESLRDAIN 402

                         90
                 ....*....|....
gi 31377618  426 AVINDKSYKENIMR 439
Cdd:PLN02764 403 SVMKRDSEIGNLVK 416
PLN02670 PLN02670
transferase, transferring glycosyl groups
 347-408 2.66e-04

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 43.35  E-value: 2.66e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31377618  347 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 408
Cdd:PLN02670 342 IHVGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQGLNTRLLHGKKLGL 403
murG PRK00726
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
 367-439 1.42e-03

undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional


Pssm-ID: 234825 [Multi-domain]  Cd Length: 357  Bit Score: 40.88  E-value: 1.42e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31377618  367 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 439
Cdd:PRK00726 257 ICRAGASTVAELAAAGLPAILVPLphaaDDHQTANARALVDAGAALLIPQSDLTPEKLAEKLLELLSDPERLEAMAE 333
GT28_Beta-DGS-like cd17507
beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol ...
 355-440 1.48e-03

beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340861 [Multi-domain]  Cd Length: 364  Bit Score: 40.76  E-value: 1.48e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31377618 355 NDLLGhpMTRAFITHAGSHGVYESICNGVPMVM-MPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSY 433
Cdd:cd17507 262 NELMA--ASDLVITKPGGLTISEALARGLPVIIyDPIPGQEEENADFLENNGAGIIARDPEELLEIVARLIDPPSLLRMM 339


                ....*..
gi 31377618 434 KENIMRL 440
Cdd:cd17507 340 SEAAKEL 346
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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