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Conserved domains on  [gi|7524978|ref|NP_050076|]
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hypothetical protein DidioMp09 (mitochondrion) [Dictyostelium discoideum]

Protein Classification

LAGLIDADG family homing endonuclease( domain architecture ID 10469810)

LAGLIDADG family homing endonuclease belongs to a large family of homing endonucleases that each contain one or two copies of a motif that resembles the consensus sequence LAGLIDADG and is directly involved in the DNA cutting process

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
13-107 5.24e-13

LAGLIDADG endonuclease;


:

Pssm-ID: 395767  Cd Length: 101  Bit Score: 63.04  E-value: 5.24e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7524978     13 WVGLMDGVGSIEVNHYRMKNL---QYRLVLNVNDSSENMAMLLKIQQVIG-GYLIKRKEKALIAWTINN-KMQIEDVIKI 87
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgyRVRLRFQISLHSKDENLLEKIKNYLGiGSISKRKNDNTVIYIISNsKKSLNIIIPY 80

                          90       100
                  ....*....|....*....|
gi 7524978     88 FEDYNLVTVRKRNQLQFLKE 107
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKKI 100
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
144-230 6.73e-07

LAGLIDADG endonuclease;


:

Pssm-ID: 395767  Cd Length: 101  Bit Score: 46.47  E-value: 6.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7524978    144 FSGFVEATGSFCIRAQKEKY---------FRIA-HRYDMPLLLNLIIKFNITTKLREQKNEQYAIEIYKKT-LLEVLITH 212
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSykgyrvrlrFQISlHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNSKkSLNIIIPY 80

                          90
                  ....*....|....*...
gi 7524978    213 FEKYPLLGDKKNSLETFK 230
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFK 98
 
Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
13-107 5.24e-13

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 63.04  E-value: 5.24e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7524978     13 WVGLMDGVGSIEVNHYRMKNL---QYRLVLNVNDSSENMAMLLKIQQVIG-GYLIKRKEKALIAWTINN-KMQIEDVIKI 87
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgyRVRLRFQISLHSKDENLLEKIKNYLGiGSISKRKNDNTVIYIISNsKKSLNIIIPY 80

                          90       100
                  ....*....|....*....|
gi 7524978     88 FEDYNLVTVRKRNQLQFLKE 107
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKKI 100
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
144-230 6.73e-07

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 46.47  E-value: 6.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7524978    144 FSGFVEATGSFCIRAQKEKY---------FRIA-HRYDMPLLLNLIIKFNITTKLREQKNEQYAIEIYKKT-LLEVLITH 212
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSykgyrvrlrFQISlHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNSKkSLNIIIPY 80

                          90
                  ....*....|....*...
gi 7524978    213 FEKYPLLGDKKNSLETFK 230
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFK 98
 
Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
13-107 5.24e-13

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 63.04  E-value: 5.24e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7524978     13 WVGLMDGVGSIEVNHYRMKNL---QYRLVLNVNDSSENMAMLLKIQQVIG-GYLIKRKEKALIAWTINN-KMQIEDVIKI 87
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgyRVRLRFQISLHSKDENLLEKIKNYLGiGSISKRKNDNTVIYIISNsKKSLNIIIPY 80

                          90       100
                  ....*....|....*....|
gi 7524978     88 FEDYNLVTVRKRNQLQFLKE 107
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKKI 100
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
144-230 6.73e-07

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 46.47  E-value: 6.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7524978    144 FSGFVEATGSFCIRAQKEKY---------FRIA-HRYDMPLLLNLIIKFNITTKLREQKNEQYAIEIYKKT-LLEVLITH 212
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSykgyrvrlrFQISlHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNSKkSLNIIIPY 80

                          90
                  ....*....|....*...
gi 7524978    213 FEKYPLLGDKKNSLETFK 230
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFK 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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