protein ITPRID1 isoform 2 [Mus musculus]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| KRAP_IP3R_bind super family | cl20655 | Ki-ras-induced actin-interacting protein-IP3R-interacting domain; This family includes the ... |
1-68 | 1.58e-28 | ||
Ki-ras-induced actin-interacting protein-IP3R-interacting domain; This family includes the N-terminus of the actin-interacting protein sperm-specific antigen 2, or KRAP (Ki-ras-induced actin-interacting protein). This region is found to be the residues that interact with inositol 1,4,5-trisphosphate receptor (IP3R). KRAP was first localized as a membrane-bound form with extracellular regions suggesting it might be involved in the regulation of filamentous actin and signals from the outside of the cells. It has now been shown to be critical for the proper subcellular localization and function of IP3R. Inositol 1,4,5-trisphosphate receptor functions as the Ca2+ release channel on specialized endoplasmic reticulum membranes, so the subcellular localization of IP3R is crucial for its proper function. The actual alignment was detected with superfamily member pfam14722: Pssm-ID: 464280 Cd Length: 145 Bit Score: 111.66 E-value: 1.58e-28
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| Name | Accession | Description | Interval | E-value | ||
| KRAP_IP3R_bind | pfam14722 | Ki-ras-induced actin-interacting protein-IP3R-interacting domain; This family includes the ... |
1-68 | 1.58e-28 | ||
Ki-ras-induced actin-interacting protein-IP3R-interacting domain; This family includes the N-terminus of the actin-interacting protein sperm-specific antigen 2, or KRAP (Ki-ras-induced actin-interacting protein). This region is found to be the residues that interact with inositol 1,4,5-trisphosphate receptor (IP3R). KRAP was first localized as a membrane-bound form with extracellular regions suggesting it might be involved in the regulation of filamentous actin and signals from the outside of the cells. It has now been shown to be critical for the proper subcellular localization and function of IP3R. Inositol 1,4,5-trisphosphate receptor functions as the Ca2+ release channel on specialized endoplasmic reticulum membranes, so the subcellular localization of IP3R is crucial for its proper function. Pssm-ID: 464280 Cd Length: 145 Bit Score: 111.66 E-value: 1.58e-28
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| Name | Accession | Description | Interval | E-value | ||
| KRAP_IP3R_bind | pfam14722 | Ki-ras-induced actin-interacting protein-IP3R-interacting domain; This family includes the ... |
1-68 | 1.58e-28 | ||
Ki-ras-induced actin-interacting protein-IP3R-interacting domain; This family includes the N-terminus of the actin-interacting protein sperm-specific antigen 2, or KRAP (Ki-ras-induced actin-interacting protein). This region is found to be the residues that interact with inositol 1,4,5-trisphosphate receptor (IP3R). KRAP was first localized as a membrane-bound form with extracellular regions suggesting it might be involved in the regulation of filamentous actin and signals from the outside of the cells. It has now been shown to be critical for the proper subcellular localization and function of IP3R. Inositol 1,4,5-trisphosphate receptor functions as the Ca2+ release channel on specialized endoplasmic reticulum membranes, so the subcellular localization of IP3R is crucial for its proper function. Pssm-ID: 464280 Cd Length: 145 Bit Score: 111.66 E-value: 1.58e-28
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