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Conserved domains on  [gi|2172664212|ref|NP_001386119|]
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coiled-coil domain-containing protein 177 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4659 super family cl37893
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...
 328-701 5.01e-73

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.


The actual alignment was detected with superfamily member pfam15558:

Pssm-ID: 464768 [Multi-domain]  Cd Length: 374  Bit Score: 241.09  E-value: 5.01e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 328 GVPERDRKIAALMLARHQEERLLLEQRAAAHGQWEQQRVRAEQRREREEREKQRALEQGRRAWAAQVEERRGRRGREERE 407
Cdd:pfam15558   1 VVPERDRKIAALMLARHKEEQRMRELQQQAALAWEELRRRDQKRQETLERERRLLLQQSQEQWQAEKEQRKARLGREERR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 408 AARRRQQQCERSEERRRELAERQGLLRRERVERAARDDRLRKLQQEQNLKQREEGLQEGRERAELVRRERAQRAARARQK 487
Cdd:pfam15558  81 RADRREKQVIEKESRWREQAEDQENQRQEKLERARQEAEQRKQCQEQRLKEKEEELQALREQNSLQLQERLEEACHKRQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 488 QEGQLQREKRELSRAERARHEALLRGRVRQQQEEREGLRSSLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKE 567
Cdd:pfam15558 161 KEREEQKKVQENNLSELLNHQARKVLVDCQAKAEELLRRLSLEQSLQRSQENYEQLVEERHRELREKAQKEEEQFQRAKW 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 568 AAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLE 647
Cdd:pfam15558 241 RAEEKEEERQEHKEALAELADRKIQQARQVAHKTVQDKAQRARELNLEREKNHHILKLKVEKEEKCHREGIKEAIKKKEQ 320

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2172664212 648 RSEQLSRERRSALESARSTARASFHVREKVREETNTRSFDRMVREAQLHASLDR 701
Cdd:pfam15558 321 RSEQISREKEATLEEARKTARASFHMREKVREETNNRTFDKMALEAQLHASLQR 374
 
Name Accession Description Interval E-value
DUF4659 pfam15558
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...
 328-701 5.01e-73

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.


Pssm-ID: 464768 [Multi-domain]  Cd Length: 374  Bit Score: 241.09  E-value: 5.01e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 328 GVPERDRKIAALMLARHQEERLLLEQRAAAHGQWEQQRVRAEQRREREEREKQRALEQGRRAWAAQVEERRGRRGREERE 407
Cdd:pfam15558   1 VVPERDRKIAALMLARHKEEQRMRELQQQAALAWEELRRRDQKRQETLERERRLLLQQSQEQWQAEKEQRKARLGREERR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 408 AARRRQQQCERSEERRRELAERQGLLRRERVERAARDDRLRKLQQEQNLKQREEGLQEGRERAELVRRERAQRAARARQK 487
Cdd:pfam15558  81 RADRREKQVIEKESRWREQAEDQENQRQEKLERARQEAEQRKQCQEQRLKEKEEELQALREQNSLQLQERLEEACHKRQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 488 QEGQLQREKRELSRAERARHEALLRGRVRQQQEEREGLRSSLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKE 567
Cdd:pfam15558 161 KEREEQKKVQENNLSELLNHQARKVLVDCQAKAEELLRRLSLEQSLQRSQENYEQLVEERHRELREKAQKEEEQFQRAKW 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 568 AAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLE 647
Cdd:pfam15558 241 RAEEKEEERQEHKEALAELADRKIQQARQVAHKTVQDKAQRARELNLEREKNHHILKLKVEKEEKCHREGIKEAIKKKEQ 320

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2172664212 648 RSEQLSRERRSALESARSTARASFHVREKVREETNTRSFDRMVREAQLHASLDR 701
Cdd:pfam15558 321 RSEQISREKEATLEEARKTARASFHMREKVREETNNRTFDKMALEAQLHASLQR 374
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 448-680 9.06e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 9.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 448 RKLQQEQNLKQREEGLQEGRERAELVRRERAQRAARARQKQEGQLQREKRELSRAE-RARHEALLRGRVRQQQEEREGLR 526
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEElRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 527 SslEASLGRAQENYEQLQEQRARELRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKA 606
Cdd:COG1196   296 E--LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2172664212 607 RRVIQTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLERSEQLSRERRSALESARSTARASFHVREKVREE 680
Cdd:COG1196   374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
PTZ00121 PTZ00121
MAEBL; Provisional
 445-687 5.51e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 5.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  445 DRLRKLQQEQNLKQR---EEGLQEGRERAELVRRERAQRAARARQKQEGQLQREKRELSRAERARHEAllrGRVRQQQEE 521
Cdd:PTZ00121  1555 EELKKAEEKKKAEEAkkaEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA---EELKKAEEE 1631

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  522 REGLRS--SLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAE 599
Cdd:PTZ00121  1632 KKKVEQlkKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  600 EAVQQKARRViqTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLERSEQLSRERRSALESARSTARASfhVREKVRE 679
Cdd:PTZ00121  1712 AEEKKKAEEL--KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV--IEEELDE 1787


                   ....*...
gi 2172664212  680 ETNTRSFD 687
Cdd:PTZ00121  1788 EDEKRRME 1795
 
Name Accession Description Interval E-value
DUF4659 pfam15558
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ...
 328-701 5.01e-73

Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.


Pssm-ID: 464768 [Multi-domain]  Cd Length: 374  Bit Score: 241.09  E-value: 5.01e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 328 GVPERDRKIAALMLARHQEERLLLEQRAAAHGQWEQQRVRAEQRREREEREKQRALEQGRRAWAAQVEERRGRRGREERE 407
Cdd:pfam15558   1 VVPERDRKIAALMLARHKEEQRMRELQQQAALAWEELRRRDQKRQETLERERRLLLQQSQEQWQAEKEQRKARLGREERR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 408 AARRRQQQCERSEERRRELAERQGLLRRERVERAARDDRLRKLQQEQNLKQREEGLQEGRERAELVRRERAQRAARARQK 487
Cdd:pfam15558  81 RADRREKQVIEKESRWREQAEDQENQRQEKLERARQEAEQRKQCQEQRLKEKEEELQALREQNSLQLQERLEEACHKRQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 488 QEGQLQREKRELSRAERARHEALLRGRVRQQQEEREGLRSSLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKE 567
Cdd:pfam15558 161 KEREEQKKVQENNLSELLNHQARKVLVDCQAKAEELLRRLSLEQSLQRSQENYEQLVEERHRELREKAQKEEEQFQRAKW 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 568 AAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLE 647
Cdd:pfam15558 241 RAEEKEEERQEHKEALAELADRKIQQARQVAHKTVQDKAQRARELNLEREKNHHILKLKVEKEEKCHREGIKEAIKKKEQ 320

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2172664212 648 RSEQLSRERRSALESARSTARASFHVREKVREETNTRSFDRMVREAQLHASLDR 701
Cdd:pfam15558 321 RSEQISREKEATLEEARKTARASFHMREKVREETNNRTFDKMALEAQLHASLQR 374
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 448-680 9.06e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 9.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 448 RKLQQEQNLKQREEGLQEGRERAELVRRERAQRAARARQKQEGQLQREKRELSRAE-RARHEALLRGRVRQQQEEREGLR 526
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEElRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 527 SslEASLGRAQENYEQLQEQRARELRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKA 606
Cdd:COG1196   296 E--LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2172664212 607 RRVIQTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLERSEQLSRERRSALESARSTARASFHVREKVREE 680
Cdd:COG1196   374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
PTZ00121 PTZ00121
MAEBL; Provisional
 445-687 5.51e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.22  E-value: 5.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  445 DRLRKLQQEQNLKQR---EEGLQEGRERAELVRRERAQRAARARQKQEGQLQREKRELSRAERARHEAllrGRVRQQQEE 521
Cdd:PTZ00121  1555 EELKKAEEKKKAEEAkkaEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA---EELKKAEEE 1631

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  522 REGLRS--SLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAE 599
Cdd:PTZ00121  1632 KKKVEQlkKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  600 EAVQQKARRViqTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLERSEQLSRERRSALESARSTARASfhVREKVRE 679
Cdd:PTZ00121  1712 AEEKKKAEEL--KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV--IEEELDE 1787


                   ....*...
gi 2172664212  680 ETNTRSFD 687
Cdd:PTZ00121  1788 EDEKRRME 1795
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 314-693 1.09e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 314 ERIVRQVRAERGLRGVPERDRKIAALMLARHQEERLLLEQRAAAHGQWEQQRVRAEQRREREEREKQRALEQGRRAWAAQ 393
Cdd:COG1196   281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 394 VEERRGRRGREEREAARRRQQQCERSEERRRELAERQGLLRRERVERAARDDRLRKLQQEQNLKQREEGLQEGRERAELV 473
Cdd:COG1196   361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 474 RRERAQRAARARQKQEGQLQREKRELSRAERARHEALLRGRVRQQQEEREGLRSSLEASLGRAQENYEQLQEQRARELRE 553
Cdd:COG1196   441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 554 RARREELQGRRAKEAAERKEREhqAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTRLEKERAQRANKEKVERDEDC 633
Cdd:COG1196   521 GLAGAVAVLIGVEAAYEAALEA--ALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 634 RRRELLQAIGRKLERSEQLSRERRSALESARSTARASFHVREKVREETNTRSFDRMVREA 693
Cdd:COG1196   599 AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 331-632 1.23e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 1.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 331 ERDRKIAAlmlaRHQEERLLLEQRAAAHGQWEQQRVRAEQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAAR 410
Cdd:COG1196   206 ERQAEKAE----RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 411 RRQQQCERSEERRRELAERQGLLRRERVERAARDDRLRKLQQEQNLKQREEGLQEGRERAELVRRERAQRAARARQKQEG 490
Cdd:COG1196   282 ELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 491 QLQREKRELSRAERARHEALLRGRVRQQQEEREGLR-SSLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKEAA 569
Cdd:COG1196   362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAElAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2172664212 570 ERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTRLEKERAQRANKEKVERDED 632
Cdd:COG1196   442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 491-702 9.74e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.16  E-value: 9.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 491 QLQREKRELSRAERARHEALLRGRVRQQQEEREGL---RSSLEASLGRAQENYEQLQEQRARELRERARREELQgRRAKE 567
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELEAELEELeaeLEELEAELAELEAELEELRLELEELELELEEAQAEE-YELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 568 AAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTRLEKERAQRANK-EKVERDEDCRRRELLQAIGRKL 646
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEElEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2172664212 647 ERSEQLSRERRSALESARSTARASFHVREKVREETNTRSFDRMVREAQLHASLDRK 702
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431
PTZ00121 PTZ00121
MAEBL; Provisional
 445-680 1.66e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 1.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  445 DRLRKLQQEqnlKQREEglqEGRERAELVRRERAQRAARARQKQEGQLQREKRELSRAERARHEALLRGRVRQQQEEREG 524
Cdd:PTZ00121  1408 DELKKAAAA---KKKAD---EAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE 1481

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  525 LRSSLEASlGRAQENYEQLQEQRARELRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAEEAvqQ 604
Cdd:PTZ00121  1482 AKKADEAK-KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEL--K 1558

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2172664212  605 KARrviqtrlEKERAQRANKEKVERDEDCRRRELLQAI--GRKLERSEQLSRERRSALESARSTARASFHVREKVREE 680
Cdd:PTZ00121  1559 KAE-------EKKKAEEAKKAEEDKNMALRKAEEAKKAeeARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAE 1629
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 331-669 1.91e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.01  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 331 ERDRKIAALMLARHQEERLLLEQRAAAHGqwEQQRVRAEQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAAR 410
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEE--LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 411 RRQQQCERSEERRRELAERQGLLRRERVERAARDDRLRKLQQEQNLKQREEGLQEGRERAELVRRERAQRAARARQKQEG 490
Cdd:COG1196   328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 491 QLQREKRELSRAERARHEALLrgrvRQQQEEREGLRSSLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKEAAE 570
Cdd:COG1196   408 AEEALLERLERLEEELEELEE----ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 571 RKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTrlekERAQRANKEKVERDEDCRRRELLQAIGRKLERSE 650
Cdd:COG1196   484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA----VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVA 559

                         330
                  ....*....|....*....
gi 2172664212 651 QLSRERRSALESARSTARA 669
Cdd:COG1196   560 AAAIEYLKAAKAGRATFLP 578
PTZ00121 PTZ00121
MAEBL; Provisional
 445-702 1.98e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  445 DRLRKLQQ----EQNLKQREEGLQEGRERAELVRRERAQRAARARQKQE---GQLQREKRELSRAERARHEALLRGRVRQ 517
Cdd:PTZ00121  1525 DEAKKAEEakkaDEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEedkNMALRKAEEAKKAEEARIEEVMKLYEEE 1604

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  518 QQEEREGLRSSLEASLgraqeNYEQL-QEQRARELRERARREELQGRRAKEAAERKEREHQAHLEALARAGE--RRLQHA 594
Cdd:PTZ00121  1605 KKMKAEEAKKAEEAKI-----KAEELkKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEedKKKAEE 1679

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  595 AQVAEEAVQQKARRVIQTRLEKERAQRANK---EKVERDEDCRRRELLQAIgrKLERSEQLSRERRSALESARSTARASF 671
Cdd:PTZ00121  1680 AKKAEEDEKKAAEALKKEAEEAKKAEELKKkeaEEKKKAEELKKAEEENKI--KAEEAKKEAEEDKKKAEEAKKDEEEKK 1757

                          250       260       270
                   ....*....|....*....|....*....|.
gi 2172664212  672 HVREKVREETNTRSFDRMVREAQLHASLDRK 702
Cdd:PTZ00121  1758 KIAHLKKEEEKKAEEIRKEKEAVIEEELDEE 1788
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
445-682 3.66e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  445 DRLRKLQQE-QNLKQREEGLQEGRERAELVRRERAQRAARARQKQEGQLQREKRELSRAERARHE-ALLRGRVRQQQEER 522
Cdd:COG4913    225 EAADALVEHfDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRlELLEAELEELRAEL 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  523 EGL---RSSLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAE 599
Cdd:COG4913    305 ARLeaeLERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212  600 eavqqkARRVIQTRLEKERAQRANKEKverdedcRRRELLQAIGRKLERSEQLSRERRSaLESARSTARASFH-VREKVR 678
Cdd:COG4913    385 ------LRAEAAALLEALEEELEALEE-------ALAEAEAALRDLRRELRELEAEIAS-LERRKSNIPARLLaLRDALA 450


                   ....
gi 2172664212  679 EETN 682
Cdd:COG4913    451 EALG 454
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 362-701 4.23e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 4.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 362 EQQRVRAEQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQQQCERSEERRRELAERQGLLRRERVERA 441
Cdd:COG1196   206 ERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 442 ARDDRLRKLQQEQNLKQREEGLQEGRERAElvrreraqraararqKQEGQLQREKRELSRAERARHEALLrgRVRQQQEE 521
Cdd:COG1196   286 AQAEEYELLAELARLEQDIARLEERRRELE---------------ERLEELEEELAELEEELEELEEELE--ELEEELEE 348

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 522 REGLRSSLEASLGRAQENYEQLQEQrarelRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAEEA 601
Cdd:COG1196   349 AEEELEEAEAELAEAEEALLEAEAE-----LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 602 VQQKARRVIQTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLERSEQLSRERRSALESARSTARASFHVREKVREet 681
Cdd:COG1196   424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA-- 501

                         330       340
                  ....*....|....*....|
gi 2172664212 682 NTRSFDRMVREAQLHASLDR 701
Cdd:COG1196   502 DYEGFLEGVKAALLLAGLRG 521
PRK12705 PRK12705
hypothetical protein; Provisional
 490-636 4.76e-03

hypothetical protein; Provisional


Pssm-ID: 237178 [Multi-domain]  Cd Length: 508  Bit Score: 40.08  E-value: 4.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 490 GQLQREKRELSRAERARHEALLRGRVRQQQEEREGLRSSLEASLGRAQENYEQLQEQRARELRERARREELQGRRAK--- 566
Cdd:PRK12705   23 VLLKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKldn 102

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2172664212 567 -----EAAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTRLEKERAQRANKEKVERDEDCRRR 636
Cdd:PRK12705  103 lenqlEEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEAERK 177
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 310-701 5.35e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.31  E-value: 5.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 310 AQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEERLLLEQRAAAHGQWEQQRVRAEQRREREEREKQRALEQGRRA 389
Cdd:COG1196   379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 390 WAAQVEERRGRRGREEREAARRRQQQCERSEERRRELAERQGLLRRERVERAARDDRLRKLQQEQNLKQREEGLQEGRER 469
Cdd:COG1196   459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 470 AELVRRERAQRAARARQKQEGQLQREKRELSRAERARHEALLRGRVRQQQEEREGLRSSLEASLGRAQEN-YEQLQEQRA 548
Cdd:COG1196   539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLrEADARYYVL 618

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2172664212 549 RELRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVIQTRLEKERAQRANKEKVE 628
Cdd:COG1196   619 GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA 698

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2172664212 629 RDEDCRRRELLQAIGRKLERSEQLSRERRSALESARSTARASFHVREKVREETNTRSFDRMVREAQLHASLDR 701
Cdd:COG1196   699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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