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Conserved domains on  [gi|2082815036|ref|NP_001382791|]
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cytoplasmic polyadenylated homeobox-like protein 2 [Homo sapiens]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10052840)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

Gene Ontology:  GO:0003677|GO:0006357|GO:0043565
PubMed:  1357790|26464018|21557080

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 31-79 4.27e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


:

Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 58.02  E-value: 4.27e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2082815036  31 FSEELLQELKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRARL 79
Cdd:cd00086     7 FTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKL 55
 
Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 31-79 4.27e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 58.02  E-value: 4.27e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2082815036  31 FSEELLQELKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRARL 79
Cdd:cd00086     7 FTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKL 55
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 31-78 2.43e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 55.72  E-value: 2.43e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 2082815036   31 FSEELLQELKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRAR 78
Cdd:smart00389   8 FTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAK 55
Homeodomain pfam00046
Homeodomain;
31-78 3.05e-08

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 49.81  E-value: 3.05e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2082815036  31 FSEELLQELKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRAR 78
Cdd:pfam00046   7 FTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAK 54
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
39-88 3.43e-03

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 37.80  E-value: 3.43e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2082815036  39 LKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRARlppEERQRIF 88
Cdd:COG5576    66 LEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAK---EKKKRSG 112
 
Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 31-79 4.27e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 58.02  E-value: 4.27e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2082815036  31 FSEELLQELKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRARL 79
Cdd:cd00086     7 FTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKL 55
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 31-78 2.43e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 55.72  E-value: 2.43e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 2082815036   31 FSEELLQELKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRAR 78
Cdd:smart00389   8 FTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAK 55
Homeodomain pfam00046
Homeodomain;
31-78 3.05e-08

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 49.81  E-value: 3.05e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2082815036  31 FSEELLQELKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRAR 78
Cdd:pfam00046   7 FTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAK 54
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
39-88 3.43e-03

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 37.80  E-value: 3.43e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2082815036  39 LKEIFGENGYPDFTTRKTLANKFDCPVNVINNWFQNNRARlppEERQRIF 88
Cdd:COG5576    66 LEREFEINPYPSSITRIKLSLLLNMPPKSVQIWFQNKRAK---EKKKRSG 112
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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