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Conserved domains on  [gi|2022781848|ref|NP_001381130|]
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snRNA-activating protein complex subunit 4 isoform a [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
817-1215 1.91e-14

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 79.21  E-value: 1.91e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  817 PRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSEL 896
Cdd:PHA03247  2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL 2695
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  897 LQ------EKRLQEARAREATRGpvvLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAakpgTSGSwq 970
Cdd:PHA03247  2696 TSladpppPPPTPEPAPHALVSA---TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT----TAGP-- 2766
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  971 EAGTSAKDKRLSTMQALPLAPVFSEAEgTAPAASQAPALGPGQISVSCPESGLGQSQAPAAsrkqGLPEAPPFLPAAPSP 1050
Cdd:PHA03247  2767 PAPAPPAAPAAGPPRRLTRPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASPAG----PLPPPTSAQPTAPPP 2841
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1051 TPLPVQPlSLTHIGGphVATSVPlpVTWVLTAQGLLPVPV----PAVVSLPRPAGTPGPAGLLATLLPPLTEtRAAQGPR 1126
Cdd:PHA03247  2842 PPGPPPP-SLPLGGS--VAPGGD--VRRRPPSRSPAAKPAaparPPVRRLARPAVSRSTESFALPPDQPERP-PQPQAPP 2915
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1127 APALSSSWQPPANMNREPEPSCRTDTPAPPThALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRL 1206
Cdd:PHA03247  2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT-TDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTP 2994

                   ....*....
gi 2022781848 1207 PAFGGVIPA 1215
Cdd:PHA03247  2995 PLTGHSLSR 3003
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
401-448 4.00e-14

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


:

Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 67.63  E-value: 4.00e-14
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 2022781848   401 KGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLH 448
Cdd:smart00717    1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLK 48
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
297-357 2.30e-08

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 51.93  E-value: 2.30e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2022781848  297 WSREEEERLQAIAAAHGhLEWQKIAEELGtSRSAFQCLQKFQQHNKA-LKRKEWTEEEDRML 357
Cdd:pfam13921    1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPkISRGPWSKEEDQRL 60
PLN03091 super family cl33633
hypothetical protein; Provisional
399-502 2.69e-08

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PLN03091:

Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 58.06  E-value: 2.69e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  399 LKKGYWAPEEDAKLLQAVAKYGEQDWfkirEEVPGRSDAQ-----CRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGv 473
Cdd:PLN03091    12 LRKGLWSPEEDEKLLRHITKYGHGCW----SSVPKQAGLQrcgksCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLG- 86
                           90       100
                   ....*....|....*....|....*....
gi 2022781848  474 GHWAKIASELPHRSGSQCLSKWKIMMGKK 502
Cdd:PLN03091    87 NRWSQIAAQLPGRTDNEIKNLWNSCLKKK 115
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
346-397 1.44e-07

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


:

Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 49.14  E-value: 1.44e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 2022781848   346 RKEWTEEEDRMLTQLVQEMRVGShipYRRIVYYMEGRDSMQLIYRWTKSLDP 397
Cdd:smart00717    1 KGEWTEEEDELLIELVKKYGKNN---WEKIAKELPGRTAEQCRERWRNLLKP 49
SANT super family cl21498
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
262-305 1.36e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


The actual alignment was detected with superfamily member pfam13921:

Pssm-ID: 473887 [Multi-domain]  Cd Length: 60  Bit Score: 41.14  E-value: 1.36e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2022781848  262 DWEKISNInfEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERL 305
Cdd:pfam13921   19 DWKQIAKE--LGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
817-1215 1.91e-14

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 79.21  E-value: 1.91e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  817 PRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSEL 896
Cdd:PHA03247  2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL 2695
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  897 LQ------EKRLQEARAREATRGpvvLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAakpgTSGSwq 970
Cdd:PHA03247  2696 TSladpppPPPTPEPAPHALVSA---TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT----TAGP-- 2766
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  971 EAGTSAKDKRLSTMQALPLAPVFSEAEgTAPAASQAPALGPGQISVSCPESGLGQSQAPAAsrkqGLPEAPPFLPAAPSP 1050
Cdd:PHA03247  2767 PAPAPPAAPAAGPPRRLTRPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASPAG----PLPPPTSAQPTAPPP 2841
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1051 TPLPVQPlSLTHIGGphVATSVPlpVTWVLTAQGLLPVPV----PAVVSLPRPAGTPGPAGLLATLLPPLTEtRAAQGPR 1126
Cdd:PHA03247  2842 PPGPPPP-SLPLGGS--VAPGGD--VRRRPPSRSPAAKPAaparPPVRRLARPAVSRSTESFALPPDQPERP-PQPQAPP 2915
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1127 APALSSSWQPPANMNREPEPSCRTDTPAPPThALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRL 1206
Cdd:PHA03247  2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT-TDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTP 2994

                   ....*....
gi 2022781848 1207 PAFGGVIPA 1215
Cdd:PHA03247  2995 PLTGHSLSR 3003
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
401-448 4.00e-14

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 67.63  E-value: 4.00e-14
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 2022781848   401 KGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLH 448
Cdd:smart00717    1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLK 48
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
404-447 1.15e-13

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 66.44  E-value: 1.15e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2022781848  404 WAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRL 447
Cdd:cd00167      2 WTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
401-447 2.37e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.52  E-value: 2.37e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2022781848  401 KGYWAPEEDAKLLQAVAKYGEqDWFKIREEVPGRSDAQCRDRYLRRL 447
Cdd:pfam00249    1 RGPWTPEEDELLLEAVEKLGN-RWKKIAKLLPGRTDNQCKNRWQNYL 46
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
297-357 2.30e-08

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 51.93  E-value: 2.30e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2022781848  297 WSREEEERLQAIAAAHGhLEWQKIAEELGtSRSAFQCLQKFQQHNKA-LKRKEWTEEEDRML 357
Cdd:pfam13921    1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPkISRGPWSKEEDQRL 60
PLN03091 PLN03091
hypothetical protein; Provisional
399-502 2.69e-08

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 58.06  E-value: 2.69e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  399 LKKGYWAPEEDAKLLQAVAKYGEQDWfkirEEVPGRSDAQ-----CRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGv 473
Cdd:PLN03091    12 LRKGLWSPEEDEKLLRHITKYGHGCW----SSVPKQAGLQrcgksCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLG- 86
                           90       100
                   ....*....|....*....|....*....
gi 2022781848  474 GHWAKIASELPHRSGSQCLSKWKIMMGKK 502
Cdd:PLN03091    87 NRWSQIAAQLPGRTDNEIKNLWNSCLKKK 115
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
294-342 2.73e-08

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 51.46  E-value: 2.73e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*....
gi 2022781848   294 KQEWSREEEERLQAIAAAHGHLEWQKIAEELGTsRSAFQCLQKFQQHNK 342
Cdd:smart00717    1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPG-RTAEQCRERWRNLLK 48
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
346-397 1.44e-07

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 49.14  E-value: 1.44e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 2022781848   346 RKEWTEEEDRMLTQLVQEMRVGShipYRRIVYYMEGRDSMQLIYRWTKSLDP 397
Cdd:smart00717    1 KGEWTEEEDELLIELVKKYGKNN---WEKIAKELPGRTAEQCRERWRNLLKP 49
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
290-339 1.64e-07

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 49.23  E-value: 1.64e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2022781848  290 PSINKQEWSREEEERLQAIaAAHGHLEWQKIAEELGtsRSAFQCLQKFQQ 339
Cdd:cd11659      1 PSIKKTEWTREEDEKLLHL-AKLLPTQWRTIAPIVG--RTAQQCLERYNK 47
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
256-357 2.99e-07

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 54.79  E-value: 2.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  256 NRLDShDWEKISNINFE------GSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLeWQKIAEELGtSRS 329
Cdd:COG5147     29 EDLKA-LVKKLGPNNWSkvasllISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ-WSTIADYKD-RRT 105
                           90       100
                   ....*....|....*....|....*...
gi 2022781848  330 AFQCLQKFQQHNKALKRKEWTEEEDRML 357
Cdd:COG5147    106 AQQCVERYVNTLEDLSSTHDSKLQRRNE 133
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
836-1230 4.44e-07

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 54.20  E-value: 4.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  836 SSAQSTPGHLFPNVPAQ-EASKSASHKGSRRLASSRVER----TLPQASLLASTGPrPKPKTVSELLQEKRLQEAR--AR 908
Cdd:pfam17823   11 FSLPLSESHAAPADPRHfVLNKMWNGAGKQNASGDAVPRadnkSSEQ*NFCAATAA-PAPVTLTKGTSAAHLNSTEvtAE 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  909 EATRG-----PVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLS-GPGAPAAAKPGTSGSwqeAGTSAKDKRLS 982
Cdd:pfam17823   90 HTPHGtdlsePATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSeAFSAPRAAACRANAS---AAPRAAIAAAS 166
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  983 TMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTH 1062
Cdd:pfam17823  167 APHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVG 246
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1063 IGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETraaQGPRAPAlsSSWQPPANMNR 1142
Cdd:pfam17823  247 TVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQA---QGPIIQV--STDQPVHNTAG 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1143 EPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSShadPPEAEPPWSGRLPAfggVIPATEPRGTP 1222
Cdd:pfam17823  322 EPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSM---IPEVEATSPTTQPS---PLLPTQGAAGP 395

                   ....*...
gi 2022781848 1223 GSPSGTQE 1230
Cdd:pfam17823  396 GILLAPEQ 403
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
334-453 5.18e-07

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 54.02  E-value: 5.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  334 LQKFQQHNKALKRKE--WTEEEDRMLTQLVQEM------RVGSHIPYRrivyyMEGRDSMqliyRWTKSLDPGLKKGYWA 405
Cdd:COG5147      6 NKELQIKLMQTKRKGgsWKRTEDEDLKALVKKLgpnnwsKVASLLISS-----TGKQSSN----RWNNHLNPQLKKKNWS 76
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2022781848  406 PEEDAKLLQAVAKYGEQdWFKIREEVPGRSDAQCRDRYLRRLHFSLKK 453
Cdd:COG5147     77 EEEDEQLIDLDKELGTQ-WSTIADYKDRRTAQQCVERYVNTLEDLSST 123
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
349-412 3.31e-06

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 45.76  E-value: 3.31e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2022781848  349 WTEEEDRMLTQLVQEMrvgsHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKL 412
Cdd:pfam13921    1 WTEEEDEKLLKLVEKY----GNDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
470-496 4.31e-06

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 44.87  E-value: 4.31e-06
                           10        20
                   ....*....|....*....|....*..
gi 2022781848  470 KYGVGHWAKIASELPHRSGSQCLSKWK 496
Cdd:cd00167     16 KYGKNNWEKIAKELPGRTPKQCRERWR 42
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
470-496 5.70e-06

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 44.52  E-value: 5.70e-06
                            10        20
                    ....*....|....*....|....*..
gi 2022781848   470 KYGVGHWAKIASELPHRSGSQCLSKWK 496
Cdd:smart00717   18 KYGKNNWEKIAKELPGRTAEQCRERWR 44
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
399-495 4.68e-05

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 47.86  E-value: 4.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  399 LKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVgHWAK 478
Cdd:COG5147     18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGT-QWST 96
                           90
                   ....*....|....*..
gi 2022781848  479 IASELPHRSGSQCLSKW 495
Cdd:COG5147     97 IADYKDRRTAQQCVERY 113
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
262-305 1.36e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 41.14  E-value: 1.36e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2022781848  262 DWEKISNInfEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERL 305
Cdd:pfam13921   19 DWKQIAKE--LGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
193-359 1.91e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.03  E-value: 1.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  193 RKSVVSDRLQRL---LQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQdiNQLPEEALLGNRLD-SHDWEKISN 268
Cdd:TIGR00618  220 RKQVLEKELKHLreaLQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELR--AQEAVLEETQERINrARKAAPLAA 297
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  269 InfegSRSAEEIRKFWQNSeHPSINKQEWSReEEERLQAIAAAHGHLEWQKIAEELGTSRSafQCLQKFQQHNKALKRKE 348
Cdd:TIGR00618  298 H----IKAVTQIEQQAQRI-HTELQSKMRSR-AKLLMKRAAHVKQQSSIEEQRRLLQTLHS--QEIHIRDAHEVATSIRE 369
                          170
                   ....*....|....*
gi 2022781848  349 ----WTEEEDRMLTQ 359
Cdd:TIGR00618  370 iscqQHTLTQHIHTL 384
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
817-1215 1.91e-14

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 79.21  E-value: 1.91e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  817 PRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSEL 896
Cdd:PHA03247  2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL 2695
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  897 LQ------EKRLQEARAREATRGpvvLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAakpgTSGSwq 970
Cdd:PHA03247  2696 TSladpppPPPTPEPAPHALVSA---TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT----TAGP-- 2766
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  971 EAGTSAKDKRLSTMQALPLAPVFSEAEgTAPAASQAPALGPGQISVSCPESGLGQSQAPAAsrkqGLPEAPPFLPAAPSP 1050
Cdd:PHA03247  2767 PAPAPPAAPAAGPPRRLTRPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASPAG----PLPPPTSAQPTAPPP 2841
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1051 TPLPVQPlSLTHIGGphVATSVPlpVTWVLTAQGLLPVPV----PAVVSLPRPAGTPGPAGLLATLLPPLTEtRAAQGPR 1126
Cdd:PHA03247  2842 PPGPPPP-SLPLGGS--VAPGGD--VRRRPPSRSPAAKPAaparPPVRRLARPAVSRSTESFALPPDQPERP-PQPQAPP 2915
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1127 APALSSSWQPPANMNREPEPSCRTDTPAPPThALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRL 1206
Cdd:PHA03247  2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT-TDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTP 2994

                   ....*....
gi 2022781848 1207 PAFGGVIPA 1215
Cdd:PHA03247  2995 PLTGHSLSR 3003
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
401-448 4.00e-14

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 67.63  E-value: 4.00e-14
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 2022781848   401 KGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLH 448
Cdd:smart00717    1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLK 48
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
404-447 1.15e-13

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 66.44  E-value: 1.15e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2022781848  404 WAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRL 447
Cdd:cd00167      2 WTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
PHA03247 PHA03247
large tegument protein UL36; Provisional
812-1232 3.54e-13

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 74.97  E-value: 3.54e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  812 RKALPPRLPQAGARD--PPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPK 889
Cdd:PHA03247  2572 RPAPRPSEPAVTSRArrPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPER 2651
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  890 PKTVSELLQEKRLQEAR-------AREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLS-GPGAPAAA 961
Cdd:PHA03247  2652 PRDDPAPGRVSRPRRARrlgraaqASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPpGPAAARQA 2731
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  962 KPGTSGSWQEAGTSAKdkrlstmqalPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLgqSQAPAASRKQGLPEAP 1041
Cdd:PHA03247  2732 SPALPAAPAPPAVPAG----------PATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRL--TRPAVASLSESRESLP 2799
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1042 pfLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSlprPAGTPGPAGLLATLLPPLTETRA 1121
Cdd:PHA03247  2800 --SPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP---LGGSVAPGGDVRRRPPSRSPAAK 2874
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1122 AQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEAdgsvafvPGEAQVAREIPEPRTSSHADPPEAEPP 1201
Cdd:PHA03247  2875 PAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQ-------PQPPPPPQPQPPPPPPPRPQPPLAPTT 2947
                          410       420       430
                   ....*....|....*....|....*....|.
gi 2022781848 1202 WSGRLPAFGGVIPAtePRGTPGSPSGTQEPR 1232
Cdd:PHA03247  2948 DPAGAGEPSGAVPQ--PWLGALVPGRVAVPR 2976
PHA03247 PHA03247
large tegument protein UL36; Provisional
812-1307 8.42e-13

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 73.82  E-value: 8.42e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  812 RKALPPRLPQA--GARDPPvHLLQASSSAQSTPGHLFPNVPAQEASKSASH-------KGSRRLASSRV---ERTLPQAS 879
Cdd:PHA03247  2481 RRPAEARFPFAagAAPDPG-GGGPPDPDAPPAPSRLAPAILPDEPVGEPVHprmltwiRGLEELASDDAgdpPPPLPPAA 2559
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  880 LLASTG-----PRPKPKTVSELLQEKRLQEARAREATRG--PVVLPSQLLVSSSVILQPPLPHTPHgRPAPGPTVLNVPL 952
Cdd:PHA03247  2560 PPAAPDrsvppPRPAPRPSEPAVTSRARRPDAPPQSARPraPVDDRGDPRGPAPPSPLPPDTHAPD-PPPPSPSPAANEP 2638
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  953 SGPGaPAAAKPGTSGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASqaPALGPGQISVSCPESGLGQSQAP-AA 1031
Cdd:PHA03247  2639 DPHP-PPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAAR--PTVGSLTSLADPPPPPPTPEPAPhAL 2715
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1032 SRKQGLPEAP-------PFLPAAPSPTPLPVQPLSlthIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVvSLPRPAGTP- 1103
Cdd:PHA03247  2716 VSATPLPPGPaaarqasPALPAAPAPPAVPAGPAT---PGGPARPARPPTTAGPPAPAPPAAPAAGPPR-RLTRPAVASl 2791
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1104 GPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANmnrEPEPSCRTDTPAPPTHALSQSPAEADGSVAfvPGeAQVARE 1183
Cdd:PHA03247  2792 SESRESLPSPWDPADPPAAVLAPAAALPPAASPAGP---LPPPTSAQPTAPPPPPGPPPPSLPLGGSVA--PG-GDVRRR 2865
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1184 IP------------EPRTSSHADPPEAEPPWSGRLPAFGgviPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGA 1251
Cdd:PHA03247  2866 PPsrspaakpaapaRPPVRRLARPAVSRSTESFALPPDQ---PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2022781848 1252 LDLEKPPLPQPGPEKGALDlgllsqegeaatqQWLGGQRGVRVPLLGSRLPYQPPA 1307
Cdd:PHA03247  2943 LAPTTDPAGAGEPSGAVPQ-------------PWLGALVPGRVAVPRFRVPQPAPS 2985
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
401-447 2.37e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 62.52  E-value: 2.37e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2022781848  401 KGYWAPEEDAKLLQAVAKYGEqDWFKIREEVPGRSDAQCRDRYLRRL 447
Cdd:pfam00249    1 RGPWTPEEDELLLEAVEKLGN-RWKKIAKLLPGRTDNQCKNRWQNYL 46
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
404-457 3.28e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 60.02  E-value: 3.28e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2022781848  404 WAPEEDAKLLQAVAKYGeQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWN 457
Cdd:pfam13921    1 WTEEEDEKLLKLVEKYG-NDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWS 53
PHA03378 PHA03378
EBNA-3B; Provisional
901-1267 5.12e-10

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 64.32  E-value: 5.12e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  901 RLQEARAREATRGPVVL----PSQLLVSSSVILQPPLPHTPHgRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSA 976
Cdd:PHA03378   437 RTEQPRATPHSQAPTVVlhrpPTQPLEGPTGPLSVQAPLEPW-QPLPHPQVTPVILHQPPAQGVQAHGSMLDLLEKDDED 515
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  977 KDKRLSTMQALPLAP----------VFSE---AEGTAPAASQA------PALGPGQISV-------------SCPESGLG 1024
Cdd:PHA03378   516 MEQRVMATLLPPSPPqpragrrapcVYTEdldIESDEPASTEPvhdqllPAPGLGPLQIqpltspttsqlasSAPSYAQT 595
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1025 QSQAPAASRKQGLPEAPPFLPA--APSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGT 1102
Cdd:PHA03378   596 PWPVPHPSQTPEPPTTQSHIPEtsAPRQWPMPLRPIPMRPLRMQPITFNVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQ 675
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1103 PGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSV---AFVPGEAQ 1179
Cdd:PHA03378   676 PSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRArppAAAPGRAR 755
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1180 VAREIPEPRTSSHADPPEAEPpwsgRLPAFGGVIPATEPRgtpGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPL 1259
Cdd:PHA03378   756 PPAAAPGRARPPAAAPGAPTP----QPPPQAPPAPQQRPR---GAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQILRQL 828

                   ....*...
gi 2022781848 1260 PQPGPEKG 1267
Cdd:PHA03378   829 LTGGVKRG 836
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
297-357 2.30e-08

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 51.93  E-value: 2.30e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2022781848  297 WSREEEERLQAIAAAHGhLEWQKIAEELGtSRSAFQCLQKFQQHNKA-LKRKEWTEEEDRML 357
Cdd:pfam13921    1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPkISRGPWSKEEDQRL 60
PLN03091 PLN03091
hypothetical protein; Provisional
399-502 2.69e-08

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 58.06  E-value: 2.69e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  399 LKKGYWAPEEDAKLLQAVAKYGEQDWfkirEEVPGRSDAQ-----CRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGv 473
Cdd:PLN03091    12 LRKGLWSPEEDEKLLRHITKYGHGCW----SSVPKQAGLQrcgksCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLG- 86
                           90       100
                   ....*....|....*....|....*....
gi 2022781848  474 GHWAKIASELPHRSGSQCLSKWKIMMGKK 502
Cdd:PLN03091    87 NRWSQIAAQLPGRTDNEIKNLWNSCLKKK 115
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
294-342 2.73e-08

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 51.46  E-value: 2.73e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*....
gi 2022781848   294 KQEWSREEEERLQAIAAAHGHLEWQKIAEELGTsRSAFQCLQKFQQHNK 342
Cdd:smart00717    1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPG-RTAEQCRERWRNLLK 48
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
814-1200 5.24e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 57.69  E-value: 5.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  814 ALPPRLPQAGARDPPVhlLQASSSAQSTPghlfPNVPAQEASKSASHKGSRRLASSrvertlPQASLLASTGPRPKPKTV 893
Cdd:PRK07764   380 RLERRLGVAGGAGAPA--AAAPSAAAAAP----AAAPAPAAAAPAAAAAPAPAAAP------QPAPAPAPAPAPPSPAGN 447
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  894 SELLQEKRLQEARAREATRGPVVLPSQllvssSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPgtSGSWQEAG 973
Cdd:PRK07764   448 APAGGAPSPPPAAAPSAQPAPAPAAAP-----EPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATL--RERWPEIL 520
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  974 TSAKDKRLSTMQAL---------------------PLAPVFSEAE-----------------------GTAPAASQAPAL 1009
Cdd:PRK07764   521 AAVPKRSRKTWAILlpeatvlgvrgdtlvlgfstgGLARRFASPGnaevlvtalaeelggdwqveavvGPAPGAAGGEGP 600
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1010 GPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPV- 1088
Cdd:PRK07764   601 PAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAa 680
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1089 PVPAVVSLPRPAGTPGPAGLLATLLPPlteTRAAQGPRAPAlsSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEAD 1168
Cdd:PRK07764   681 PPPAPAPAAPAAPAGAAPAQPAPAPAA---TPPAGQADDPA--AQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAP 755
                          410       420       430
                   ....*....|....*....|....*....|..
gi 2022781848 1169 GSVAFVPGEAQVAREIPEPRTSSHADPPEAEP 1200
Cdd:PRK07764   756 AQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
346-397 1.44e-07

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 49.14  E-value: 1.44e-07
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 2022781848   346 RKEWTEEEDRMLTQLVQEMRVGShipYRRIVYYMEGRDSMQLIYRWTKSLDP 397
Cdd:smart00717    1 KGEWTEEEDELLIELVKKYGKNN---WEKIAKELPGRTAEQCRERWRNLLKP 49
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
290-339 1.64e-07

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 49.23  E-value: 1.64e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 2022781848  290 PSINKQEWSREEEERLQAIaAAHGHLEWQKIAEELGtsRSAFQCLQKFQQ 339
Cdd:cd11659      1 PSIKKTEWTREEDEKLLHL-AKLLPTQWRTIAPIVG--RTAQQCLERYNK 47
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
820-1227 2.99e-07

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 55.56  E-value: 2.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  820 PQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRvERTLPQASLLASTGPRPKPKTVSELLQE 899
Cdd:PHA03307    24 PPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPG-PGTEAPANESRSTPTWSLSTLAPASPAR 102
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  900 KRLQEARAREATRGPVVLPSQLLVSSSVilQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDK 979
Cdd:PHA03307   103 EGSPTPPGPSSPDPPPPTPPPASPPPSP--APDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPE 180
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  980 RLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQA---------PAASRKQGLPEAPPFLPAAPSP 1050
Cdd:PHA03307   181 ETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAAddagasssdSSSSESSGCGWGPENECPLPRP 260
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1051 TPLPVQPLSLTHIgGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGP-RAPA 1129
Cdd:PHA03307   261 APITLPTRIWEAS-GWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSEsSRGA 339
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1130 LSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLPAF 1209
Cdd:PHA03307   340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDA 419
                          410
                   ....*....|....*...
gi 2022781848 1210 GGVIPATEPRGTPGSPSG 1227
Cdd:PHA03307   420 GAASGAFYARYPLLTPSG 437
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
256-357 2.99e-07

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 54.79  E-value: 2.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  256 NRLDShDWEKISNINFE------GSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLeWQKIAEELGtSRS 329
Cdd:COG5147     29 EDLKA-LVKKLGPNNWSkvasllISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ-WSTIADYKD-RRT 105
                           90       100
                   ....*....|....*....|....*...
gi 2022781848  330 AFQCLQKFQQHNKALKRKEWTEEEDRML 357
Cdd:COG5147    106 AQQCVERYVNTLEDLSSTHDSKLQRRNE 133
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
296-340 3.14e-07

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 47.96  E-value: 3.14e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 2022781848  296 EWSREEEERLQAIAAAHGHLEWQKIAEELGTsRSAFQCLQKFQQH 340
Cdd:cd00167      1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPG-RTPKQCRERWRNL 44
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
836-1230 4.44e-07

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 54.20  E-value: 4.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  836 SSAQSTPGHLFPNVPAQ-EASKSASHKGSRRLASSRVER----TLPQASLLASTGPrPKPKTVSELLQEKRLQEAR--AR 908
Cdd:pfam17823   11 FSLPLSESHAAPADPRHfVLNKMWNGAGKQNASGDAVPRadnkSSEQ*NFCAATAA-PAPVTLTKGTSAAHLNSTEvtAE 89
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  909 EATRG-----PVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLS-GPGAPAAAKPGTSGSwqeAGTSAKDKRLS 982
Cdd:pfam17823   90 HTPHGtdlsePATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSeAFSAPRAAACRANAS---AAPRAAIAAAS 166
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  983 TMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTH 1062
Cdd:pfam17823  167 APHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVG 246
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1063 IGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETraaQGPRAPAlsSSWQPPANMNR 1142
Cdd:pfam17823  247 TVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQA---QGPIIQV--STDQPVHNTAG 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1143 EPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSShadPPEAEPPWSGRLPAfggVIPATEPRGTP 1222
Cdd:pfam17823  322 EPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSM---IPEVEATSPTTQPS---PLLPTQGAAGP 395

                   ....*...
gi 2022781848 1223 GSPSGTQE 1230
Cdd:pfam17823  396 GILLAPEQ 403
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
930-1264 5.02e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.61  E-value: 5.02e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  930 QPPLPHTPHGRPAPGPtvlnvplSGPGAPAAAKPGTSGSWQEAGT-SAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPA 1008
Cdd:PRK07764   397 AAPSAAAAAPAAAPAP-------AAAAPAAAAAPAPAAAPQPAPApAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPA 469
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1009 LGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAA---------------------------PSPTPLPVQP--LS 1059
Cdd:PRK07764   470 PAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDaatlrerwpeilaavpkrsrktwaillPEATVLGVRGdtLV 549
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1060 LTH--------IGGPHVATSVplpVTwVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALS 1131
Cdd:PRK07764   550 LGFstgglarrFASPGNAEVL---VT-ALAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPA 625
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1132 SSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEA-----DGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRL 1206
Cdd:PRK07764   626 APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDasdggDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP 705
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2022781848 1207 PAFGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGP 1264
Cdd:PRK07764   706 AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPA 763
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
876-1248 5.05e-07

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 54.77  E-value: 5.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  876 PQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLpsqllVSSSVILQP---PLPHTP-HGRPAPGPTVLNVP 951
Cdd:pfam03154  189 PGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTL-----IQQTPTLHPqrlPSPHPPlQPMTQPPPPSQVSP 263
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  952 LSGPGAPAAAKPGTSGSWQEAGTSAKDKRLSTmQALPLAPVFSEAEGTAPAASQAPalgpgqisvscpesglGQSQApaa 1031
Cdd:pfam03154  264 QPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPP-QPFPLTPQSSQSQVPPGPSPAAP----------------GQSQQ--- 323
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1032 srkqgLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQG-LLPVPVPAVVSLPRPAGTPGPAGLLA 1110
Cdd:pfam03154  324 -----RIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQShKHPPHLSGPSPFQMNSNLPPPPALKP 398
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1111 TLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPA-----PPTHALSQSPAEAD-GSVAFVPGEAQVAREI 1184
Cdd:pfam03154  399 LSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPpaashPPTSGLHQVPSQSPfPQHPFVPGGPPPITPP 478
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1185 PEPRTSSHADPPEAEPPWSGRlPAFGGVIPATEPRGTPG------SPSGTQEPRGPlgleKLPLRQPGPE 1248
Cdd:pfam03154  479 SGPPTSTSSAMPGIQPPSSAS-VSSSGPVPAAVSCPLPPvqikeeALDEAEEPESP----PPPPRSPSPE 543
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
334-453 5.18e-07

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 54.02  E-value: 5.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  334 LQKFQQHNKALKRKE--WTEEEDRMLTQLVQEM------RVGSHIPYRrivyyMEGRDSMqliyRWTKSLDPGLKKGYWA 405
Cdd:COG5147      6 NKELQIKLMQTKRKGgsWKRTEDEDLKALVKKLgpnnwsKVASLLISS-----TGKQSSN----RWNNHLNPQLKKKNWS 76
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2022781848  406 PEEDAKLLQAVAKYGEQdWFKIREEVPGRSDAQCRDRYLRRLHFSLKK 453
Cdd:COG5147     77 EEEDEQLIDLDKELGTQ-WSTIADYKDRRTAQQCVERYVNTLEDLSST 123
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
878-1234 1.52e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 53.25  E-value: 1.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  878 ASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVIlqPPLPHTPHGRPAPGPTVLNVPLSGPGA 957
Cdd:PHA03307    57 AGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPT--PPGPSSPDPPPPTPPPASPPPSPAPDL 134
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  958 PAAAKPGTSGSwqeagtsakdKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESG---LGQSQAPAASRK 1034
Cdd:PHA03307   135 SEMLRPVGSPG----------PPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPpaePPPSTPPAAASP 204
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1035 QGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTwVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLP 1114
Cdd:PHA03307   205 RPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGC-GWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPG 283
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1115 PLTETRAAQGPRAPALSSSwqppanmnrepepSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHAD 1194
Cdd:PHA03307   284 PASSSSSPRERSPSPSPSS-------------PGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRS 350
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 2022781848 1195 PPEAEPPwsgrlPAFGGVIPATEPRGTPGSPSGTQEPRGP 1234
Cdd:PHA03307   351 PSPSRPP-----PPADPSSPRKRPRPSRAPSSPAASAGRP 385
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
349-412 3.31e-06

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 45.76  E-value: 3.31e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2022781848  349 WTEEEDRMLTQLVQEMrvgsHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKL 412
Cdd:pfam13921    1 WTEEEDEKLLKLVEKY----GNDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
960-1170 4.24e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 51.42  E-value: 4.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  960 AAKPGTSGSWQEAGTSAKDKRLSTMQAL----PLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQ 1035
Cdd:PRK12323   362 AFRPGQSGGGAGPATAAAAPVAQPAPAAaapaAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASA 441
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1036 GLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGP----AGLLAT 1111
Cdd:PRK12323   442 RGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPaqpdAAPAGW 521
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2022781848 1112 LLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGS 1170
Cdd:PRK12323   522 VAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGD 580
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
470-496 4.31e-06

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 44.87  E-value: 4.31e-06
                           10        20
                   ....*....|....*....|....*..
gi 2022781848  470 KYGVGHWAKIASELPHRSGSQCLSKWK 496
Cdd:cd00167     16 KYGKNNWEKIAKELPGRTPKQCRERWR 42
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1000-1270 4.96e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 51.39  E-value: 4.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1000 APAASQAPAlGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVAtsvPLPVTWV 1079
Cdd:PRK07003   361 AVTGGGAPG-GGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAA---PAPPATA 436
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1080 LTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSswqppanmnREPEPSCrtdtpAPPTHA 1159
Cdd:PRK07003   437 DRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAA---------FEPAPRA-----AAPSAA 502
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1160 LSQSPAEADGSVAFVPGEAQVAREIPEPRTSShADPPEAEPPWSGrlpafGGVIPATEPRGTPGSPSGTQEPRGPLGLEK 1239
Cdd:PRK07003   503 TPAAVPDARAPAAASREDAPAAAAPPAPEARP-PTPAAAAPAARA-----GGAAAALDVLRNAGMRVSSDRGARAAAAAK 576
                          250       260       270
                   ....*....|....*....|....*....|.
gi 2022781848 1240 LPLRQPGPEKGALDLEKPPLPQPGPEKGALD 1270
Cdd:PRK07003   577 PAAAPAAAPKPAAPRVAVQVPTPRARAATGD 607
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
470-496 5.70e-06

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 44.52  E-value: 5.70e-06
                            10        20
                    ....*....|....*....|....*..
gi 2022781848   470 KYGVGHWAKIASELPHRSGSQCLSKWK 496
Cdd:smart00717   18 KYGKNNWEKIAKELPGRTAEQCRERWR 44
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
987-1215 8.81e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 50.26  E-value: 8.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  987 LPLAPVFSEAEGTAPAASQAPALGPG----QISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTH 1062
Cdd:PRK12323   361 LAFRPGQSGGGAGPATAAAAPVAQPApaaaAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQAS 440
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1063 IGGPhVATSVPLPVtwvltaqgllPVPVPAVVSLPRPAGTPGPAglLATLLPPLTETRAAQGPRAPALSSSWQPPANMNR 1142
Cdd:PRK12323   441 ARGP-GGAPAPAPA----------PAAAPAAAARPAAAGPRPVA--AAAAAAPARAAPAAAPAPADDDPPPWEELPPEFA 507
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2022781848 1143 EPEPSCRTDTPAPPTHALSQSPAEADGSVAF-VPGEAQVAREIPEPRTSSHADPPEAEPPWS--GRLPAFGGVIPA 1215
Cdd:PRK12323   508 SPAPAQPDAAPAGWVAESIPDPATADPDDAFeTLAPAPAAAPAPRAAAATEPVVAPRPPRASasGLPDMFDGDWPA 583
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
931-1138 9.92e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 50.26  E-value: 9.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  931 PPLPHTPHGRPAPG---PTVLNVPLSGPGAPAAAKPGTSGSWQEAGtSAKDKRLSTMQALPLApvfSEAEGTAPAASQAP 1007
Cdd:PRK12323   375 ATAAAAPVAQPAPAaaaPAAAAPAPAAPPAAPAAAPAAAAAARAVA-AAPARRSPAPEALAAA---RQASARGPGGAPAP 450
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1008 ALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAqglLP 1087
Cdd:PRK12323   451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAES---IP 527
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2022781848 1088 VPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAqgPRAPALSSSWQPPA 1138
Cdd:PRK12323   528 DPATADPDDAFETLAPAPAAAPAPRAAAATEPVVA--PRPPRASASGLPDM 576
PHA03247 PHA03247
large tegument protein UL36; Provisional
930-1272 1.69e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 1.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  930 QPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGT---SAKDKRLSTMQALPLAPVFSEaegtaPAASQA 1006
Cdd:PHA03247  2414 QPDPPGPPDVRFVGSEEIEELPFVSPGGDVLAGLAADGDPFFARTilgAPFSLSLLLGELFPGAPVYRR-----PAEARF 2488
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1007 P-ALGPGqisvscPESGLGQSQAPAASRKQGLPeAPPFLPAAPSPTPLPVQPLSLTH---------IGGPhvatSVPLPv 1076
Cdd:PHA03247  2489 PfAAGAA------PDPGGGGPPDPDAPPAPSRL-APAILPDEPVGEPVHPRMLTWIRgleelasddAGDP----PPPLP- 2556
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1077 twvltaqgllPVPVPAVV--SLPRPAGTPGPAGLLAtllpplteTRAAQGPRAPALSSSWQPPANmNREPEPSCRTDTPA 1154
Cdd:PHA03247  2557 ----------PAAPPAAPdrSVPPPRPAPRPSEPAV--------TSRARRPDAPPQSARPRAPVD-DRGDPRGPAPPSPL 2617
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1155 PPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLP--AFGGVIPATEPR------------- 1219
Cdd:PHA03247  2618 PPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLgrAAQASSPPQRPRrraarptvgslts 2697
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2022781848 1220 -GTPGSPSGTQEPRGPLGLEKLPLrQPGPEKGALDLEKPPL---PQPGPEKGALDLG 1272
Cdd:PHA03247  2698 lADPPPPPPTPEPAPHALVSATPL-PPGPAAARQASPALPAapaPPAVPAGPATPGG 2753
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
294-340 2.30e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 42.88  E-value: 2.30e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2022781848  294 KQEWSREEEERLQAIAAAHGHlEWQKIAEELGTsRSAFQCLQKFQQH 340
Cdd:pfam00249    1 RGPWTPEEDELLLEAVEKLGN-RWKKIAKLLPG-RTDNQCKNRWQNY 45
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
903-1202 3.29e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 48.69  E-value: 3.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  903 QEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEaGTSAKDKRLS 982
Cdd:PRK07003   372 VPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGD-DAADGDAPVP 450
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  983 TMQALPLAPVFSEAEGTA-PAASQAPALGPGqisvscpesglgqSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLT 1061
Cdd:PRK07003   451 AKANARASADSRCDERDAqPPADSGSASAPA-------------SDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1062 HIGGPHVAtSVPLPvtwvltaqgLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMN 1141
Cdd:PRK07003   518 REDAPAAA-APPAP---------EARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKP 587
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2022781848 1142 REPEPSCRTDTPAPPTHALSQSPAEAdgsvafvpgeaqvareipePRTSSHADPPEAEPPW 1202
Cdd:PRK07003   588 AAPRVAVQVPTPRARAATGDAPPNGA-------------------ARAEQAAESRGAPPPW 629
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1064-1302 3.90e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 48.33  E-value: 3.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1064 GGPHVATSVPLPVTWVLtaqgllPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNRE 1143
Cdd:PRK12323   370 GGAGPATAAAAPVAQPA------PAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARG 443
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1144 PEPSCRTDTPAPPTHALSQSPAEADgsvafvpgeaqvareiPEPRTSSHADPPEAEPPWSGRLPAFGGVIPATEPRGTPG 1223
Cdd:PRK12323   444 PGGAPAPAPAPAAAPAAAARPAAAG----------------PRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFA 507
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1224 SPSGTQEPRGPLGLEKLPLRQPG---PEKGALDLEKPPLPQPGPEKGALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSR 1300
Cdd:PRK12323   508 SPAPAQPDAAPAGWVAESIPDPAtadPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAAR 587

                   ..
gi 2022781848 1301 LP 1302
Cdd:PRK12323   588 LP 589
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
399-495 4.68e-05

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 47.86  E-value: 4.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  399 LKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVgHWAK 478
Cdd:COG5147     18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGT-QWST 96
                           90
                   ....*....|....*..
gi 2022781848  479 IASELPHRSGSQCLSKW 495
Cdd:COG5147     97 IADYKDRRTAQQCVERY 113
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
931-1216 4.74e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 47.99  E-value: 4.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  931 PPLPHTPHGRPAP---GPTVLNVPLSGP---GAPAAAKPGT-SGSWQEAGTSAKDKRLSTmqalplaPVFSEAEGTAPAA 1003
Cdd:pfam05109  449 PSSTHVPTNLTAPastGPTVSTADVTSPtpaGTTSGASPVTpSPSPRDNGTESKAPDMTS-------PTSAVTTPTPNAT 521
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1004 SQAPALGPGQISVSCPESGlgqSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQP-LSLThigGPHVATSVPLPVTWVLTA 1082
Cdd:pfam05109  522 SPTPAVTTPTPNATSPTLG---KTSPTSAVTTPTPNATSPTPAVTTPTPNATIPtLGKT---SPTSAVTTPTPNATSPTV 595
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1083 QGLLP------------VPVPAVVSLPRPAGTPGPAGLLATLLppltETRAAQGPRAPALSSSWQPPANMNR-------- 1142
Cdd:pfam05109  596 GETSPqanttnhtlggtSSTPVVTSPPKNATSAVTTGQHNITS----SSTSSMSLRPSSISETLSPSTSDNStshmpllt 671
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1143 EPEPS-----------------CRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPePRTSSHADPPEAEPPWSGR 1205
Cdd:pfam05109  672 SAHPTggenitqvtpaststhhVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTP-PKNATSPQAPSGQKTAVPT 750
                          330
                   ....*....|.
gi 2022781848 1206 LPAFGGVIPAT 1216
Cdd:pfam05109  751 VTSTGGKANST 761
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
397-443 5.69e-05

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 41.91  E-value: 5.69e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2022781848  397 PGLKKGYWAPEEDAKLLQAVAKYGEQdWFKIREEVpGRSDAQCRDRY 443
Cdd:cd11659      1 PSIKKTEWTREEDEKLLHLAKLLPTQ-WRTIAPIV-GRTAQQCLERY 45
PHA03247 PHA03247
large tegument protein UL36; Provisional
559-1059 6.24e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 6.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  559 LLSPQYMVPDMDLWVPARQSTSQPWRGGAGAWLGGPAAslsPPKGSSASQGGSKEASTTAAAPgeetsPVQVPARAHGPV 638
Cdd:PHA03247  2554 PLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDA---PPQSARPRAPVDDRGDPRGPAP-----PSPLPPDTHAPD 2625
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  639 PRSAQASHSADTRPAGAEKQALEGGRRLLTVPVETVLRVLRANTAARSCTQKEQLRQPPLPTSSPGVSSGDSVARSHVQw 718
Cdd:PHA03247  2626 PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP- 2704
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  719 lrHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDVVVPCTQASqrPAVVQTQADGLREQLQQARLASTPvftlftqlf 798
Cdd:PHA03247  2705 --PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG--PATPGGPARPARPPTTAGPPAPAP--------- 2771
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  799 hidtagclevvrerKALPPRLPQAGARDPPVhllqaSSSAQSTPGHLFPNVPAqEASKSASHKGSRRLASSRVERTLPQA 878
Cdd:PHA03247  2772 --------------PAAPAAGPPRRLTRPAV-----ASLSESRESLPSPWDPA-DPPAAVLAPAAALPPAASPAGPLPPP 2831
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  879 SLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSvilQPPLPHTPhgRPAPGPTVLNVPLSGPGAP 958
Cdd:PHA03247  2832 TSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPA---RPPVRRLA--RPAVSRSTESFALPPDQPE 2906
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  959 AAAKPgtsgswqEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQ--SQAPAASRKQG 1036
Cdd:PHA03247  2907 RPPQP-------QAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlvPGRVAVPRFRV 2979
                          490       500
                   ....*....|....*....|...
gi 2022781848 1037 LPEAPPFLPAAPSPTPLPVQPLS 1059
Cdd:PHA03247  2980 PQPAPSREAPASSTPPLTGHSLS 3002
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
938-1156 7.36e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 47.29  E-value: 7.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  938 HGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDKRlstmqalplAPVFSEAEGTAPAASQAPALGPGQISVS 1017
Cdd:PRK07764   590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGA---------AAAPAEASAAPAPGVAAPEHHPKHVAVP 660
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1018 CPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLP 1097
Cdd:PRK07764   661 DASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVP 740
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2022781848 1098 RPaGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPAnmnrEPEPSCRTDTPAPP 1156
Cdd:PRK07764   741 LP-PEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS----EEEEMAEDDAPSMD 794
PHA03378 PHA03378
EBNA-3B; Provisional
874-1209 1.19e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 46.98  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  874 TLPQASLLASTGP----RPKPKTVSELLQEKRLQEARAREAT---RGPVVL---PSQLLVSSSVILQPPLPHTPHGRPAP 943
Cdd:PHA03378   578 TSPTTSQLASSAPsyaqTPWPVPHPSQTPEPPTTQSHIPETSaprQWPMPLrpiPMRPLRMQPITFNVLVFPTPHQPPQV 657
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  944 GPTVLNV----PLSGPGAPAAAKPGTSGSWQEAGTsakdkrlsTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCP 1019
Cdd:PHA03378   658 EITPYKPtwtqIGHIPYQPSPTGANTMLPIQWAPG--------TMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAA 729
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1020 ESGLGQSQAPAASRKQGlPEAPPFLPAAPSPTPLPVQPLSlthiGGPHVATSVPLPVTWVLTAQ----GLLPVPVPAV-- 1093
Cdd:PHA03378   730 APGRARPPAAAPGRARP-PAAAPGRARPPAAAPGRARPPA----AAPGAPTPQPPPQAPPAPQQrprgAPTPQPPPQAgp 804
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1094 ----VSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSwQPPANMNREPEPSCRTDT-PAPPTHALSQSPAEAD 1168
Cdd:PHA03378   805 tsmqLMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALER-QAAAGPTPSPGSGTSDKIvQAPVFYPPVLQPIQVM 883
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2022781848 1169 GSVAFV---------------PGEAQVA-----REIPEPRTSSHADPPEAEPPWSGRLPAF 1209
Cdd:PHA03378   884 RQLGSVraaaastvtqapteyTGERRGVgpmhpTDIPPSKRAKTDAYVESQPPHGGQSHSF 944
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
404-443 1.36e-04

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 41.01  E-value: 1.36e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2022781848  404 WAPEEDAKLLQAVAKYGEQDWFKIREE---VPGRSDAQCRDRY 443
Cdd:cd11660      3 WTDEEDEALVEGVEKYGVGNWAKILKDyffVNNRTSVDLKDKW 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
262-305 1.36e-04

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 41.14  E-value: 1.36e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 2022781848  262 DWEKISNInfEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERL 305
Cdd:pfam13921   19 DWKQIAKE--LGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
292-411 3.11e-04

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 45.16  E-value: 3.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  292 INKQEWSREEEERLQAIAAAHGHLEWQKIAEELgTSRSAFQC-LQKFQQHNKALKRKEWTEEEDRMLTQLVQEMrvGSHI 370
Cdd:COG5147     18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLL-ISSTGKQSsNRWNNHLNPQLKKKNWSEEEDEQLIDLDKEL--GTQW 94
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 2022781848  371 pyRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAK 411
Cdd:COG5147     95 --STIADYKDRRTAQQCVERYVNTLEDLSSTHDSKLQRRNE 133
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
233-375 3.50e-04

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 45.16  E-value: 3.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  233 KQGREAEKEiQDINQLPE-----EALLGNRLDSHDWEKISNINFE----GSRSAEEIRKFWQNSEHPSINKQEWSREEEE 303
Cdd:COG5147    222 KKGETLALE-QEINEYKEkkglsRKQFCERIWSTDRDEDKFWPNIykklPYRDKKSIYKHLRRKYNIFEQRGKWTKEEEQ 300
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2022781848  304 RLQAIAAAHGHLeWQKIAEELGTSRSafQCLQKFQQHNK---ALKRKEWTEEEDRMLTQLVQEMRVGSHiPYRRI 375
Cdd:COG5147    301 ELAKLVVEHGGS-WTEIGKLLGRMPN--DCRDRWRDYVKcgdTLKRNRWSIEEEELLDKVVNEMRLEAQ-QSSRI 371
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
792-1319 5.91e-04

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 44.48  E-value: 5.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  792 TLFTQLFHIDTAGCLEVVRERKALPPRLP----QAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLA 867
Cdd:COG3321    839 QLWVAGVPVDWSALYPGRGRRRVPLPTYPfqreDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAA 918
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  868 SSRVERTLPQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTV 947
Cdd:COG3321    919 LALAAAALAALLALVALAAAAAALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAA 998
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  948 LNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQ 1027
Cdd:COG3321    999 AAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELA 1078
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1028 APAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAG 1107
Cdd:COG3321   1079 LAAAALALAAALAAAALALALAALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAA 1158
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1108 LLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEP 1187
Cdd:COG3321   1159 LAAALAAALLAAAALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLAL 1238
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1188 RTSSHADPPEAE-PPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEK 1266
Cdd:COG3321   1239 AAAAAAVAALAAaAAALLAALAALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAA 1318
                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2022781848 1267 GALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSRLPYQPPALCSLRALSGLLL 1319
Cdd:COG3321   1319 AALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAAAAAAAALAAAAGAAA 1371
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
966-1235 7.10e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 7.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  966 SGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGlgqSQAPAASRKQGLPEAPPflP 1045
Cdd:PHA03307    37 SGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLS---TLAPASPAREGSPTPPG--P 111
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1046 AAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGllpVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGP 1125
Cdd:PHA03307   112 SSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAA---SPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSS 188
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1126 RAPALSSSWQPPANMNREPEP------SCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVARE----IPEPRTSSHADP 1195
Cdd:PHA03307   189 PPAEPPPSTPPAAASPRPPRRsspisaSASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPEnecpLPRPAPITLPTR 268
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2022781848 1196 PEAEPPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGPL 1235
Cdd:PHA03307   269 IWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPA 308
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
1006-1307 1.06e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1006 APALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPflPAAPSPTPLPVQplslthigGPHVATSVPLPVTWVLTAQGL 1085
Cdd:PRK07764   385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAA--APAPAAAPQPAP--------APAPAPAPPSPAGNAPAGGAP 454
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1086 LPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPAlSSSWQPPANMNREPEPS-----------CRTDTPA 1154
Cdd:PRK07764   455 SPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPA-APAAPAGADDAATLRERwpeilaavpkrSRKTWAI 533
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1155 PPTHAlsqSPAEADGSV---AFV----------PGEAQVAREIPEPRT-------------SSHADPPEAEPPWSGRLPA 1208
Cdd:PRK07764   534 LLPEA---TVLGVRGDTlvlGFStgglarrfasPGNAEVLVTALAEELggdwqveavvgpaPGAAGGEGPPAPASSGPPE 610
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1209 FGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEKGALDLGLLSQEGEAATQQWLG- 1287
Cdd:PRK07764   611 EAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAp 690
                          330       340
                   ....*....|....*....|.
gi 2022781848 1288 -GQRGVRVPLLGSRLPYQPPA 1307
Cdd:PRK07764   691 aAPAGAAPAQPAPAPAATPPA 711
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
398-502 1.11e-03

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 42.37  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  398 GLKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVP-GRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGvGHW 476
Cdd:PLN03212    22 GMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGlLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLG-NRW 100
                           90       100
                   ....*....|....*....|....*.
gi 2022781848  477 AKIASELPHRSGSQCLSKWKIMMGKK 502
Cdd:PLN03212   101 SLIAGRIPGRTDNEIKNYWNTHLRKK 126
PHA03247 PHA03247
large tegument protein UL36; Provisional
942-1186 1.25e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  942 APGPTVLNVPLSGpGAPAAAKPGTSGSWQ-EAGTSAKDKRlstmqalPLAPVFSEAEGTAPAASQAPALGPGQISVSCPE 1020
Cdd:PHA03247   254 APAPPPVVGEGAD-RAPETARGATGPPPPpEAAAPNGAAA-------PPDGVWGAALAGAPLALPAPPDPPPPAPAGDAE 325
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1021 SGLGQSQAPAASRKQGLPEA--PPFLPAAPSPTPLPvqPLSLTHI-GGPHVATSVPLPVTWVLTA--------------- 1082
Cdd:PHA03247   326 EEDDEDGAMEVVSPLPRPRQhyPLGFPKRRRPTWTP--PSSLEDLsAGRHHPKRASLPTRKRRSArhaatpfargpggdd 403
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1083 QGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTEtraAQGPRAPALSSSWQPPANMNREPEPSCRTDT---------- 1152
Cdd:PHA03247   404 QTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAE---PGSDDGPAPPPERQPPAPATEPAPDDPDDATrkaldalrer 480
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 2022781848 1153 --PAPPTHALSQ----SPAEADGSVAFVPGEAQVAREIPE 1186
Cdd:PHA03247   481 rpPEPPGADLAEllgrHPDTAGTVVRLAAREAAIAREVAE 520
PHA03379 PHA03379
EBNA-3A; Provisional
676-1234 1.25e-03

EBNA-3A; Provisional


Pssm-ID: 223066 [Multi-domain]  Cd Length: 935  Bit Score: 43.51  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  676 RVLRANTAARSCTQKEQLRQPPLPTSSpgvssgdsVARSHVQWLRHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDV 755
Cdd:PHA03379   388 RLLLMRAGKLTERAREALEKASEPTYG--------TPRPPVEKPRPEVPQSLETATSHGSAQVPEPPPVHDLEPGPLHDQ 459
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  756 --VVPCTQASQRPAVVQTQADGLREQ--LQQARLASTPVFTLFTQLFHIDTAGCLEVvrERKALPPRLPQAGARDP-PVH 830
Cdd:PHA03379   460 hsMAPCPVAQLPPGPLQDLEPGDQLPgvVQDGRPACAPVPAPAGPIVRPWEASLSQV--PGVAFAPVMPQPMPVEPvPVP 537
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  831 LLQASSSAQSTPGHLFPNVPAQEAsksashkGSRRLAssrvERTLPqasllASTGPRPkPKTVSELLQEKRLQEARA-RE 909
Cdd:PHA03379   538 TVALERPVCPAPPLIAMQGPGETS-------GIVRVR----ERWRP-----APWTPNP-PRSPSQMSVRDRLARLRAeAQ 600
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  910 ATRGPV-VLPSQL-LVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTsakdkrlstmQAL 987
Cdd:PHA03379   601 PYQASVeVQPPQLtQVSPQQPMEYPLEPEQQMFPGSPFSQVADVMRAGGVPAMQPQYFDLPLQQPIS----------QGA 670
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  988 PLAPVFSEAEGTAPAASQAPALgpgqisvscPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPH 1067
Cdd:PHA03379   671 PLAPLRASMGPVPPVPATQPQY---------FDIPLTEPINQGASAAHFLPQQPMEGPLVPERWMFQGATLSQSVRPGVA 741
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1068 VATSVPLPVTWVLTAQGllpvpvPAVVSLPRPAgTPGP-AGLLATLLPPLTETRAAQGPRapALSSSWQPPANMNREPEP 1146
Cdd:PHA03379   742 QSQYFDLPLTQPINHGA------PAAHFLHQPP-MEGPwVPEQWMFQGAPPSQGTDVVQH--QLDALGYVLHVLNHPGVP 812
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1147 ScrtdTPAPPTHALSQS----PAEADGSvafvpGEAQVAREIPEP-RTSSHADPPEAEPPWSGRLPafgGVIPATEPRGT 1221
Cdd:PHA03379   813 V----SPAVNQYHVSQAafglPIDEDES-----GEGSDTSEPCEAlDLSIHGRPCPQAPEWPVQGE---GGQDATEVLDL 880
                          570
                   ....*....|...
gi 2022781848 1222 pgSPSGTQEPRGP 1234
Cdd:PHA03379   881 --SIHGRPRPRTP 891
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
193-359 1.91e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.03  E-value: 1.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  193 RKSVVSDRLQRL---LQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQdiNQLPEEALLGNRLD-SHDWEKISN 268
Cdd:TIGR00618  220 RKQVLEKELKHLreaLQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELR--AQEAVLEETQERINrARKAAPLAA 297
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  269 InfegSRSAEEIRKFWQNSeHPSINKQEWSReEEERLQAIAAAHGHLEWQKIAEELGTSRSafQCLQKFQQHNKALKRKE 348
Cdd:TIGR00618  298 H----IKAVTQIEQQAQRI-HTELQSKMRSR-AKLLMKRAAHVKQQSSIEEQRRLLQTLHS--QEIHIRDAHEVATSIRE 369
                          170
                   ....*....|....*
gi 2022781848  349 ----WTEEEDRMLTQ 359
Cdd:TIGR00618  370 iscqQHTLTQHIHTL 384
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
954-1234 3.17e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.14  E-value: 3.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  954 GPGAPAAAKPGtsgswqeagtsakdkrlstmqALPlapvfseaegtAPAASQAPALGPGQISVSCPESGlgqsQAPAASR 1033
Cdd:PRK07003   368 PGGGVPARVAG---------------------AVP-----------APGARAAAAVGASAVPAVTAVTG----AAGAALA 411
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1034 KQGLPEAPPFLPAAPSPTPLPVQplslthiggphVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTP--GPAGLLAT 1111
Cdd:PRK07003   412 PKAAAAAAATRAEAPPAAPAPPA-----------TADRGDDAADGDAPVPAKANARASADSRCDERDAQPpaDSGSASAP 480
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1112 LLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHA--LSQSPAEADGSVAFVPGEAQVAREI----- 1184
Cdd:PRK07003   481 ASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPapEARPPTPAAAAPAARAGGAAAALDVlrnag 560
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2022781848 1185 -----PEPRTSSHADPPEAEPPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGP 1234
Cdd:PRK07003   561 mrvssDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAAR 615
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
470-499 4.38e-03

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 36.78  E-value: 4.38e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2022781848  470 KYGVGHWAKIASELP---HRSGSQCLSKWKIMM 499
Cdd:cd11660     17 KYGVGNWAKILKDYFfvnNRTSVDLKDKWRNLK 49
PRK10263 PRK10263
DNA translocase FtsK; Provisional
905-1232 7.26e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.22  E-value: 7.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  905 ARAREATRGPVVLPSQLLVSSSVILQP-------PLPHTPHGRPAPGPTvlnvplSGPGAPAAAKPGTSGS--WQEagts 975
Cdd:PRK10263   330 TQSWAAPVEPVTQTPPVASVDVPPAQPtvawqpvPGPQTGEPVIAPAPE------GYPQQSQYAQPAVQYNepLQQ---- 399
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  976 akdkrlstmqalPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPflPAAPSPTPLPV 1055
Cdd:PRK10263   400 ------------PVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQS--TFAPQSTYQTE 465
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1056 QPlslthiggphvatsVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRapaLSSSWQ 1135
Cdd:PRK10263   466 QT--------------YQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQ---LAAWYQ 528
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848 1136 PPANMNREPEPSCRTdtpAPPTHALSQSPAEAdgsvafVPGEAQVAREIPEPRTSSHADPPEAEPPWSgrlPAFGGVipa 1215
Cdd:PRK10263   529 PIPEPVKEPEPIKSS---LKAPSVAAVPPVEA------AAAVSPLASGVKKATLATGAAATVAAPVFS---LANSGG--- 593
                          330
                   ....*....|....*..
gi 2022781848 1216 tePRGTPGSPSGTQEPR 1232
Cdd:PRK10263   594 --PRPQVKEGIGPQLPR 608
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
939-1061 9.20e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 9.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022781848  939 GRPAPGPTVLNVPLSGPGAPAAAKPGTSGSwQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSC 1018
Cdd:PRK14951   369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAA-AAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVAL 447
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 2022781848 1019 PESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLT 1061
Cdd:PRK14951   448 APAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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