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Conserved domains on  [gi|1904615183|ref|NP_001373795|]
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uncharacterized protein C22orf31 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF4662 super family cl21379
Domain of unknown function (DUF4662); This family of proteins is found in eukaryotes. Proteins ...
1-222 1.75e-117

Domain of unknown function (DUF4662); This family of proteins is found in eukaryotes. Proteins in this family are approximately 290 amino acids in length.


The actual alignment was detected with superfamily member pfam15578:

Pssm-ID: 464771  Cd Length: 269  Bit Score: 336.47  E-value: 1.75e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904615183   1 MARTCAKQNINAPAPATTSSWEVVRNPLIASSFSLVKLVLRRQLKNKCCPPPCKFGEGKLSKRLKHKDDSVMKATQQARK 80
Cdd:pfam15578  41 TAKTCASQNIPAPTPGTTSSWEVVKNPLISSSFSLVKLVLRRQLKDKCCPFPEKFGEKKPEKKLKPKDKATRRATQRNRI 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904615183  81 RNFISSKSKQPAGH-------RRPAGGIRESKESSKEKKLTVRQDLEDRYAEHVAATQALPQDSGTAAWKGRVLLPETQK 153
Cdd:pfam15578 121 RNQIKSKLKQPPGQppgrrpaRRPAGGIEESKESSKEKKQTVEQDLEERYAEHVAATQDLPTDAGTAAWKGPALLPETRK 200
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1904615183 154 RQQLSEDTLTIHGLPTEGYQALYHAVVEPMLWNPSGTPKRYSLELGKAIKQKLWEALCSQGAISEGAQR 222
Cdd:pfam15578 201 RQMLSEDTLTIHGLPRELYRALYHSVVEPMLWNPSGTPKRYSLELGKAIKQKLWEALCTQAAAPEAAQP 269
 
Name Accession Description Interval E-value
DUF4662 pfam15578
Domain of unknown function (DUF4662); This family of proteins is found in eukaryotes. Proteins ...
1-222 1.75e-117

Domain of unknown function (DUF4662); This family of proteins is found in eukaryotes. Proteins in this family are approximately 290 amino acids in length.


Pssm-ID: 464771  Cd Length: 269  Bit Score: 336.47  E-value: 1.75e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904615183   1 MARTCAKQNINAPAPATTSSWEVVRNPLIASSFSLVKLVLRRQLKNKCCPPPCKFGEGKLSKRLKHKDDSVMKATQQARK 80
Cdd:pfam15578  41 TAKTCASQNIPAPTPGTTSSWEVVKNPLISSSFSLVKLVLRRQLKDKCCPFPEKFGEKKPEKKLKPKDKATRRATQRNRI 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904615183  81 RNFISSKSKQPAGH-------RRPAGGIRESKESSKEKKLTVRQDLEDRYAEHVAATQALPQDSGTAAWKGRVLLPETQK 153
Cdd:pfam15578 121 RNQIKSKLKQPPGQppgrrpaRRPAGGIEESKESSKEKKQTVEQDLEERYAEHVAATQDLPTDAGTAAWKGPALLPETRK 200
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1904615183 154 RQQLSEDTLTIHGLPTEGYQALYHAVVEPMLWNPSGTPKRYSLELGKAIKQKLWEALCSQGAISEGAQR 222
Cdd:pfam15578 201 RQMLSEDTLTIHGLPRELYRALYHSVVEPMLWNPSGTPKRYSLELGKAIKQKLWEALCTQAAAPEAAQP 269
 
Name Accession Description Interval E-value
DUF4662 pfam15578
Domain of unknown function (DUF4662); This family of proteins is found in eukaryotes. Proteins ...
1-222 1.75e-117

Domain of unknown function (DUF4662); This family of proteins is found in eukaryotes. Proteins in this family are approximately 290 amino acids in length.


Pssm-ID: 464771  Cd Length: 269  Bit Score: 336.47  E-value: 1.75e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904615183   1 MARTCAKQNINAPAPATTSSWEVVRNPLIASSFSLVKLVLRRQLKNKCCPPPCKFGEGKLSKRLKHKDDSVMKATQQARK 80
Cdd:pfam15578  41 TAKTCASQNIPAPTPGTTSSWEVVKNPLISSSFSLVKLVLRRQLKDKCCPFPEKFGEKKPEKKLKPKDKATRRATQRNRI 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904615183  81 RNFISSKSKQPAGH-------RRPAGGIRESKESSKEKKLTVRQDLEDRYAEHVAATQALPQDSGTAAWKGRVLLPETQK 153
Cdd:pfam15578 121 RNQIKSKLKQPPGQppgrrpaRRPAGGIEESKESSKEKKQTVEQDLEERYAEHVAATQDLPTDAGTAAWKGPALLPETRK 200
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1904615183 154 RQQLSEDTLTIHGLPTEGYQALYHAVVEPMLWNPSGTPKRYSLELGKAIKQKLWEALCSQGAISEGAQR 222
Cdd:pfam15578 201 RQMLSEDTLTIHGLPRELYRALYHSVVEPMLWNPSGTPKRYSLELGKAIKQKLWEALCTQAAAPEAAQP 269
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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