|
Name |
Accession |
Description |
Interval |
E-value |
| DUF3668 |
pfam12416 |
Cep120 protein; This family includes the Cep120 protein which is associated with centriole ... |
118-340 |
1.01e-127 |
|
Cep120 protein; This family includes the Cep120 protein which is associated with centriole structure and function.
Pssm-ID: 463569 Cd Length: 226 Bit Score: 384.37 E-value: 1.01e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 118 KYTKFKSEIQISIALETDTKPP---VDSFKAKGAPPRDGKVPAILAGLDPRDIVAVLNEEGGYHQIGPAEYCTDSFIMSV 194
Cdd:pfam12416 1 KYTKQKPELLLSLALEKDSKPHtkdFDSFKAKPAPPRQSPGHSILANLLPSKLIPYLNEEEGYHQIGPADLCCDIFVLSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 195 TIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFNDLINPNFEPERASVRIRSSVEILRVYLALQSKLQIHLC 274
Cdd:pfam12416 81 TIAFATNLEQLVPSSMKLPEEKPGFFFYYSLLGNDVTNEPFKNLLNPNFEPERASVRIRSSLRVLRAYLSSQPYLQIHLC 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 275 CGDQSLGSTEIPLTGLLKKGSTEINQHPVTVEGAFTLDPPNRAKQKLAPIPVELAPTVGVSVALQR 340
Cdd:pfam12416 161 CGNQSLGSTEVSLQGLLPDNSTELERKPVTIEGAFVLNPPNRAKQDLPEVPLELKPTVGVTVTLRR 226
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
624-878 |
2.28e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.22 E-value: 2.28e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 624 ENQLKQKELahmQA-LAEEWKK-RDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQR 701
Cdd:COG1196 199 ERQLEPLER---QAeKAERYRElKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 702 nLQELQDSIRRAKEdcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPE--IRLQSEINLLT 779
Cdd:COG1196 276 -LEELELELEEAQA----EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEelEELEEELEEAE 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 780 LEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIR 859
Cdd:COG1196 351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430
|
250
....*....|....*....
gi 1769843730 860 NELNRLRQQEQKQYQDSTE 878
Cdd:COG1196 431 AELEEEEEEEEEALEEAAE 449
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
605-906 |
5.89e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 79.60 E-value: 5.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 605 EYKAALELEMWKEMQEDIfenQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASV 684
Cdd:COG1196 224 ELEAELLLLKLRELEAEL---EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 685 ESELQREKKELQsERQRNLQELQDSIRRAKEDCI-HQVELERL--KIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD 761
Cdd:COG1196 301 EQDIARLEERRR-ELEERLEELEEELAELEEELEeLEEELEELeeELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 762 QQN--NKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRY 839
Cdd:COG1196 380 ELEelAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1769843730 840 LAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYqDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEE 906
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAEAAARL-LLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
673-910 |
1.47e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 1.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 673 DLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKIL 752
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 753 EKEFQQFKDQQnnkpeIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEEL 832
Cdd:COG1196 301 EQDIARLEERR-----RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1769843730 833 EQMRLRylaAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDgphgsvLEEGLDDYLTRLIEERDTL 910
Cdd:COG1196 376 EAEEEL---EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE------LEEALAELEEEEEEEEEAL 444
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
630-935 |
7.67e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.79 E-value: 7.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 630 KELAHMQALAEEWKKRDRERESLVKKKvaeyTILEGKLQKTLIDLEKREQQLASVESELQR--EKKELQSERQRNLQELQ 707
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRELSSLQSEL----RRIENRLDELSQELSDASRKIGEIEKEIEQleQEEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 708 DSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYkiLEKEFQQFKDQQNNKPEIRlqSEINLLTlekVELER 787
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL--SHSRIPEIQAELSKLEEEV--SRIEARL---REIEQ 819
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 788 KLEsatksKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELeQMRLRYLAAEEKDTVKTERQ---ELLDIRNELNR 864
Cdd:TIGR02169 820 KLN-----RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL-NGKKEELEEELEELEAALRDlesRLGDLKKERDE 893
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1769843730 865 ----LRQQEQKQYQDSTEIASGKKdgpHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREILA 935
Cdd:TIGR02169 894 leaqLRELERKIEELEAQIEKKRK---RLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEE 965
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
610-910 |
4.11e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 4.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 610 LELEMwKEMQEDIFENQLKQKELAH-MQALAEEWKKRDRERESLVKKKVAEYTILEgKLQKTLIDLEKREQQLASVESEL 688
Cdd:TIGR02168 682 LEEKI-EELEEKIAELEKALAELRKeLEELEEELEQLRKELEELSRQISALRKDLA-RLEAEVEQLEERIAQLSKELTEL 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 689 QREKKELQSERQ----------RNLQELQDSIRRAKEDC---IHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKE 755
Cdd:TIGR02168 760 EAEIEELEERLEeaeeelaeaeAEIEELEAQIEQLKEELkalREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 756 FQQFKDQ--QNNKPEIRLQSEINLLTLEKVELERKLESATKSKlhykqqwgRALKELARLKQREQESQMARLkkQQEELE 833
Cdd:TIGR02168 840 LEDLEEQieELSEDIESLAAEIEELEELIEELESELEALLNER--------ASLEEALALLRSELEELSEEL--RELESK 909
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1769843730 834 QMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSvlEEGLDDYLTRLIEERDTL 910
Cdd:TIGR02168 910 RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDD--EEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
625-871 |
4.91e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.09 E-value: 4.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 625 NQLKQKELAhmqALAEEWKKRDRERESLvKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSErqrnLQ 704
Cdd:TIGR02168 220 AELRELELA---LLVLRLEELREELEEL-QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE----LY 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 705 ELQDSIRRAKEDCIHQVElerlKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVE 784
Cdd:TIGR02168 292 ALANEISRLEQQKQILRE----RLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----ELKEELESLEAELEE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 785 LERKLESATKSKLHYKQQWGRALKELARLKQRE--QESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNEL 862
Cdd:TIGR02168 363 LEAELEELESRLEELEEQLETLRSKVAQLELQIasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL 442
|
....*....
gi 1769843730 863 NRLRQQEQK 871
Cdd:TIGR02168 443 EELEEELEE 451
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
630-929 |
1.76e-11 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 68.23 E-value: 1.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 630 KELAHMQALAEEWKKRDRERESL-----VKKKVAEYTILEGKlqKTLIDLEKREQQLASVESELQREKKELQSERQRNLQ 704
Cdd:pfam17380 221 KEVQGMPHTLAPYEKMERRKESFnlaedVTTMTPEYTVRYNG--QTMTENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQ 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 705 ElqdSIRRAKEDCIHQVELERlkikQLEEDKHRLQQQLND-----AENKYKILEKEFQ----QFKDQQNNKPEIRlQSEI 775
Cdd:pfam17380 299 E---RLRQEKEEKAREVERRR----KLEEAEKARQAEMDRqaaiyAEQERMAMEREREleriRQEERKRELERIR-QEEI 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 776 -----NLLTLEKVELERK---------LESATKSKLhykqqwgraLKELARLKQREQESQMARLKKQQEELEQMRLRYLA 841
Cdd:pfam17380 371 ameisRMRELERLQMERQqknervrqeLEAARKVKI---------LEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 842 AEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGS-----VLEEGLDDYLTRLIEE---RDTLMR- 912
Cdd:pfam17380 442 EERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEeqrrkILEKELEERKQAMIEEerkRKLLEKe 521
|
330 340
....*....|....*....|..
gi 1769843730 913 -----TGVYNHEDRIISELDRQ 929
Cdd:pfam17380 522 meerqKAIYEEERRREAEEERR 543
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
595-839 |
4.36e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.00 E-value: 4.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 595 EIQTEPRETLEYKAALELEMwKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDL 674
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEV-SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 675 EKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDcihQVELERL--KIKQLEEDKHRLQQQLNDAENKYKIL 752
Cdd:TIGR02168 336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL---EEQLETLrsKVAQLELQIASLNNEIERLEARLERL 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 753 EKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ--ESQMARLKKQQE 830
Cdd:TIGR02168 413 EDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDaaERELAQLQARLD 492
|
....*....
gi 1769843730 831 ELEQMRLRY 839
Cdd:TIGR02168 493 SLERLQENL 501
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
664-878 |
6.34e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.62 E-value: 6.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 664 EGKLQKTLIDLEKREQQLASVESELqrEKKELQSERQRNLQELQDSIRRAkedcihQVELERLKIKQLEEDKHRLQQQLN 743
Cdd:TIGR02168 178 ERKLERTRENLDRLEDILNELERQL--KSLERQAEKAERYKELKAELREL------ELALLVLRLEELREELEELQEELK 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 744 DAENKYKILEKEFQQfkdqqnnkpeirLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ--ESQ 821
Cdd:TIGR02168 250 EAEEELEELTAELQE------------LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnlERQ 317
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1769843730 822 MARLKKQQEELEQMRLRYLA-----AEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTE 878
Cdd:TIGR02168 318 LEELEAQLEELESKLDELAEelaelEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
621-874 |
1.69e-10 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 65.32 E-value: 1.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 621 DIFENQLKQKElAHMQALAEEWKKRDRERESLVKKKVAEYTILEgkLQKTLIDLEKREQQLASVESELQR------EKKE 694
Cdd:COG4913 613 AALEAELAELE-EELAEAEERLEALEAELDALQERREALQRLAE--YSWDEIDVASAEREIAELEAELERldassdDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 695 LQSERQRnLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKI-----LEKEFQQFKDQQNNKpEI 769
Cdd:COG4913 690 LEEQLEE-LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLelralLEERFAAALGDAVER-EL 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 770 R--LQSEINLLTLEKVELERKLESATKSklhYKQQW--------------GRALKELARLKQR---EQESQMARLKKQQE 830
Cdd:COG4913 768 RenLEERIDALRARLNRAEEELERAMRA---FNREWpaetadldadleslPEYLALLDRLEEDglpEYEERFKELLNENS 844
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1769843730 831 ELEQMRLRYLAAEEKDTVkteRQELLDIRNELNRLRQQEQKQYQ 874
Cdd:COG4913 845 IEFVADLLSKLRRAIREI---KERIDPLNDSLKRIPFGPGRYLR 885
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
595-857 |
4.27e-10 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 62.24 E-value: 4.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 595 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYtiLEGKLQKTLIDL 674
Cdd:pfam13868 95 EKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY--LKEKAEREEERE 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 675 EKREQQLASVESELQREKKELQSERQRnlQELQDSIRRAKEDCIHQVElERLKIKQLEEDKHRLQQQLNDAENKYKILEK 754
Cdd:pfam13868 173 AEREEIEEEKEREIARLRAQQEKAQDE--KAERDELRAKLYQEEQERK-ERQKEREEAEKKARQRQELQQAREEQIELKE 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 755 EFQQFkdqqnnkpEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQwgralkELAR--LKQREQESQMARLKKQQEEL 832
Cdd:pfam13868 250 RRLAE--------EAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRL------EHRRelEKQIEEREEQRAAEREEELE 315
|
250 260
....*....|....*....|....*
gi 1769843730 833 EQMRLRYLAAEEKDTVKTERQELLD 857
Cdd:pfam13868 316 EGERLREEEAERRERIEEERQKKLK 340
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
607-940 |
4.65e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.93 E-value: 4.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 607 KAALELEmwkEMQEDIFENQLKQKELA-HMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVE 685
Cdd:TIGR02169 174 KALEELE---EVEENIERLDLIIDEKRqQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLE 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 686 SELQREKKELQ------SERQRNLQELQDSIRRAKEDCIHQV--ELERLK--IKQLEEDKHRLQQQLNDAENKYKILEKE 755
Cdd:TIGR02169 251 EELEKLTEEISelekrlEEIEQLLEELNKKIKDLGEEEQLRVkeKIGELEaeIASLERSIAEKERELEDAEERLAKLEAE 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 756 FQQFKDQ---------QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKqREQESQMARLK 826
Cdd:TIGR02169 331 IDKLLAEieelereieEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK-REINELKRELD 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 827 KQQEELEQMrlrylaaeekdtvkteRQELLDIRNELNRLRQQeQKQYQDSTE--IASGKKDGPHGSVLEEGLDDYLTRLI 904
Cdd:TIGR02169 410 RLQEELQRL----------------SEELADLNAAIAGIEAK-INELEEEKEdkALEIKKQEWKLEQLAADLSKYEQELY 472
|
330 340 350
....*....|....*....|....*....|....*.
gi 1769843730 905 EERDTLMRTgvynhEDRiISELDRQIREILAKSNAS 940
Cdd:TIGR02169 473 DLKEEYDRV-----EKE-LSKLQRELAEAEAQARAS 502
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
625-941 |
6.19e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 63.62 E-value: 6.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 625 NQLKQKELAHMQA----LAEEWKKRDRERESLVKKKVAEYTILEgklQKTLIDLEKREQQLASVESELQREKKELQSERQ 700
Cdd:PTZ00121 1500 DEAKKAAEAKKKAdeakKAEEAKKADEAKKAEEAKKADEAKKAE---EKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 701 RNLQELQDSIRRAKEDCIHQV-----ELERLKIKQL--EEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQS 773
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEARIEEVmklyeEEKKMKAEEAkkAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE 1656
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 774 EINllTLEKVELERKLESATKSKlhykqqwgralkELARLKQREQESQMARLKKQQEELEQM-RLRYLAAEEK---DTVK 849
Cdd:PTZ00121 1657 EEN--KIKAAEEAKKAEEDKKKA------------EEAKKAEEDEKKAAEALKKEAEEAKKAeELKKKEAEEKkkaEELK 1722
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 850 TERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRlieERDTLMRTGVYNHEDRIISELDRQ 929
Cdd:PTZ00121 1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRK---EKEAVIEEELDEEDEKRRMEVDKK 1799
|
330
....*....|..
gi 1769843730 930 IREIlaKSNASN 941
Cdd:PTZ00121 1800 IKDI--FDNFAN 1809
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
615-867 |
1.06e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.39 E-value: 1.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 615 WKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERE---SLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQRE 691
Cdd:PRK03918 164 YKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEkelEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEEL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 692 KKELQSERQrNLQELQDSIRRAKEdcihQVELERLKIKQLEEDKHRLQQQLNDAEnKYKILEKEFQQFKDQQNN--KPEI 769
Cdd:PRK03918 244 EKELESLEG-SKRKLEEKIRELEE----RIEELKKEIEELEEKVKELKELKEKAE-EYIKLSEFYEEYLDELREieKRLS 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 770 RLQSEINLLTLEKVELERKLESATKSKLHYKQqwgrALKELARLKQREQESQMARLKKqqEELEQMRLRyLAAEEKDTVK 849
Cdd:PRK03918 318 RLEEEINGIEERIKELEEKEERLEELKKKLKE----LEKRLEELEERHELYEEAKAKK--EELERLKKR-LTGLTPEKLE 390
|
250 260
....*....|....*....|..
gi 1769843730 850 TERQEL----LDIRNELNRLRQ 867
Cdd:PRK03918 391 KELEELekakEEIEEEISKITA 412
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
694-941 |
1.39e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 60.93 E-value: 1.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 694 ELQSERQRNLQELQDSIRRAKEdcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQ--QNNKPEIRL 771
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEK----ELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 772 QSEINLLtleKVELERKLESATKSKLHYK-------QQWGRALKELARLKQ--REQESQMARLKKQQEELEQmrLRYLAA 842
Cdd:COG4942 96 RAELEAQ---KEELAELLRALYRLGRQPPlalllspEDFLDAVRRLQYLKYlaPARREQAEELRADLAELAA--LRAELE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 843 EEKDTVKTERQELLDIRNELNRLRQQEQKQyqdsteIASGKKDgphgsvlEEGLDDYLTRLIEERDTLmrtgvynheDRI 922
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKL------LARLEKE-------LAELAAELAELQQEAEEL---------EAL 228
|
250
....*....|....*....
gi 1769843730 923 ISELDRQIREILAKSNASN 941
Cdd:COG4942 229 IARLEAEAAAAAERTPAAG 247
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
594-869 |
2.17e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 61.53 E-value: 2.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 594 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEwkKRDRERESLVKKKVAEYTILEGKLQKTLID 673
Cdd:pfam02463 732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE--REKTEKLKVEEEKEEKLKAQEEELRALEEE 809
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 674 LEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ-----VELERLKIKQLEEDKHRLQQQLNDAENK 748
Cdd:pfam02463 810 LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELerleeEITKEELLQELLLKEEELEEQKLKDELE 889
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 749 YKIL----EKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHykqqwGRALKELARLKQREQESQMAR 824
Cdd:pfam02463 890 SKEEkekeEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLE-----EADEKEKEENNKEEEEERNKR 964
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1769843730 825 LKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQE 869
Cdd:pfam02463 965 LLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIR 1009
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
685-872 |
2.72e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.94 E-value: 2.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 685 ESELQREKKELQSERQRNLQELQDSIRRAKEDcIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQN 764
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEE-LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 765 NKPEI----RLQSEINLLTLEKVELERKLE---SATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRL 837
Cdd:COG4717 127 LLPLYqeleALEAELAELPERLEELEERLEelrELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206
|
170 180 190
....*....|....*....|....*....|....*
gi 1769843730 838 RYLAAEEKdtVKTERQELLDIRNELNRLRQQEQKQ 872
Cdd:COG4717 207 RLAELEEE--LEEAQEELEELEEELEQLENELEAA 239
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
599-909 |
2.93e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 61.31 E-value: 2.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 599 EPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKRE 678
Cdd:PTZ00121 1514 EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 679 QQLAsveSELQREKKELQSERQRNLQElqdsiRRAKEDCIHQVELERLKIKQL---EEDKHRLQQQLNDAENKYKILEKE 755
Cdd:PTZ00121 1594 IEEV---MKLYEEEKKMKAEEAKKAEE-----AKIKAEELKKAEEEKKKVEQLkkkEAEEKKKAEELKKAEEENKIKAAE 1665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 756 FQQFKDQQNNKPEIRLQSEinlltlekvELERKLESATKSKLHYKqqwgRALKELArlKQREQESQMARLKKQQEELEQM 835
Cdd:PTZ00121 1666 EAKKAEEDKKKAEEAKKAE---------EDEKKAAEALKKEAEEA----KKAEELK--KKEAEEKKKAEELKKAEEENKI 1730
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 836 RLRYLAAEEKDTvKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKdgphgSVLEEGLD--DYLTRLIEERDT 909
Cdd:PTZ00121 1731 KAEEAKKEAEED-KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE-----AVIEEELDeeDEKRRMEVDKKI 1800
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
615-868 |
3.12e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.24 E-value: 3.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 615 WKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKR----------------- 677
Cdd:TIGR02169 725 IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsripeiqaelskle 804
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 678 ------EQQLASVESELQR---EKKELQSERQrNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENK 748
Cdd:TIGR02169 805 eevsriEARLREIEQKLNRltlEKEYLEKEIQ-ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 749 YKILEKEFQQFKDQQNNkpeirLQSEINLLTLEkVELERKLESATKSKLHYKQQwgrALKELARLKQREQES-------- 820
Cdd:TIGR02169 884 LGDLKKERDELEAQLRE-----LERKIEELEAQ-IEKKRKRLSELKAKLEALEE---ELSEIEDPKGEDEEIpeeelsle 954
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1769843730 821 --QMARLKKQQ-------------EELEQMRLRYLAAEEK-DTVKTERQELLDIRNELNRLRQQ 868
Cdd:TIGR02169 955 dvQAELQRVEEeiralepvnmlaiQEYEEVLKRLDELKEKrAKLEEERKAILERIEEYEKKKRE 1018
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
668-849 |
3.86e-09 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 58.01 E-value: 3.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 668 QKTLIDLEKREQQLASVESELQREKKELQsERQRNLQELQDSIRRAKEDcIHQVELER----LKIKQLEEDKHRLQQQLN 743
Cdd:COG1579 6 LRALLDLQELDSELDRLEHRLKELPAELA-ELEDELAALEARLEAAKTE-LEDLEKEIkrleLEIEEVEARIKKYEEQLG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 744 DAENkykilEKEFQQfkdqqnnkpeirLQSEINLLTLEKVELE-------RKLESATKSKLHYKQQWGRALKELARLKQr 816
Cdd:COG1579 84 NVRN-----NKEYEA------------LQKEIESLKRRISDLEdeilelmERIEELEEELAELEAELAELEAELEEKKA- 145
|
170 180 190
....*....|....*....|....*....|...
gi 1769843730 817 EQESQMARLKKQQEELEQMRLRYLAAEEKDTVK 849
Cdd:COG1579 146 ELDEELAELEAELEELEAEREELAAKIPPELLA 178
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
645-933 |
8.59e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 59.54 E-value: 8.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 645 RDRERESLV-----KKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQ-----SERQRNLQELQDSIRRAK 714
Cdd:COG4913 595 RRRIRSRYVlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeySWDEIDVASAEREIAELE 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 715 EdcihqvELERLK--IKQLEEdkhrLQQQLNDAENKYKILEKEFQQFKDQQnnkpeIRLQSEINLLTLEKVELERKLESA 792
Cdd:COG4913 675 A------ELERLDasSDDLAA----LEEQLEELEAELEELEEELDELKGEI-----GRLEKELEQAEEELDELQDRLEAA 739
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 793 TKSKLHYKQQwgRALKELARLKQREQESQMAR-LKKQQEELEQMRLRylaaeekdtvkterqelldIRNELNRLRQQEQK 871
Cdd:COG4913 740 EDLARLELRA--LLEERFAAALGDAVERELREnLEERIDALRARLNR-------------------AEEELERAMRAFNR 798
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1769843730 872 QYQDST-EIASGKKDGP-----HGSVLEEGLDDYLTRLIEERDTLMRTGVynheDRIISELDRQIREI 933
Cdd:COG4913 799 EWPAETaDLDADLESLPeylalLDRLEEDGLPEYEERFKELLNENSIEFV----ADLLSKLRRAIREI 862
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
646-870 |
1.41e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.63 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 646 DRERESLVKKKVAEYTILEGKLQktliDLEKREQQLASVESELQREKKELQSERQRnLQELQDSIRRAKEDcihQVELER 725
Cdd:COG4717 52 EKEADELFKPQGRKPELNLKELK----ELEEELKEAEEKEEEYAELQEELEELEEE-LEELEAELEELREE---LEKLEK 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 726 LK-IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEinlltlekvELERKLESA-TKSKLHYKQQW 803
Cdd:COG4717 124 LLqLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELA---------ELQEELEELlEQLSLATEEEL 194
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1769843730 804 GRALKELARLKQREQESQmARLKKQQEELEQMRlrylaaeekdtvkterQELLDIRNELNRLRQQEQ 870
Cdd:COG4717 195 QDLAEELEELQQRLAELE-EELEEAQEELEELE----------------EELEQLENELEAAALEER 244
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
636-878 |
2.38e-08 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 57.57 E-value: 2.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 636 QALAEEWKKRDRER-----ESLVKKKVAEYTILEGKL----QKTLIDLEKRE--QQLASVESELQREKKELQSERQRNLQ 704
Cdd:pfam02029 62 EAFLDRTAKREERRqkrlqEALERQKEFDPTIADEKEsvaeRKENNEEEENSswEKEEKRDSRLGRYKEEETEIREKEYQ 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 705 E--LQDSIRRAKEDCIHQvELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEK 782
Cdd:pfam02029 142 EnkWSTEVRQAEEEGEEE-EDKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGEEEVTKLK 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 783 VELERKleSATKSKLHYKQQWGRALKE----LARLKQREQEsqmarlkKQQEELEQMRLRYLAAE-EKDTVKTERQELLD 857
Cdd:pfam02029 221 VTTKRR--QGGLSQSQEREEEAEVFLEaeqkLEELRRRRQE-------KESEEFEKLRQKQQEAElELEELKKKREERRK 291
|
250 260
....*....|....*....|.
gi 1769843730 858 IRNELNRLRQQEQKQYQDSTE 878
Cdd:pfam02029 292 LLEEEEQRRKQEEAERKLREE 312
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
613-872 |
2.95e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 57.77 E-value: 2.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 613 EMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKvAEYTILEGKLQKTLIDLEKREQQLASVESELqREK 692
Cdd:PRK03918 266 ERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL-REIEKRLSRLEEEINGIEERIKELEEKEERL-EEL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 693 KELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQ 772
Cdd:PRK03918 344 KKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 773 SEINLLTLEKVELE-----RKLESATKSKL--HYKQQWGRALKELARLKQREQEsqmarLKKQQEELEQMRLRylaAEEK 845
Cdd:PRK03918 424 LKKAIEELKKAKGKcpvcgRELTEEHRKELleEYTAELKRIEKELKEIEEKERK-----LRKELRELEKVLKK---ESEL 495
|
250 260
....*....|....*....|....*..
gi 1769843730 846 DTVKTERQELLDIRNELNRLRQQEQKQ 872
Cdd:PRK03918 496 IKLKELAEQLKELEEKLKKYNLEELEK 522
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
653-936 |
4.60e-08 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 56.45 E-value: 4.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 653 VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQsERQRNLQELQDSIRRAKEDCIHQVElerlKIKQLE 732
Cdd:COG4372 33 LRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELE-QLEEELEELNEQLQAAQAELAQAQE----ELESLQ 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 733 EDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVELERKLESAtksklhykqqwgraLKELAR 812
Cdd:COG4372 108 EEAEELQEELEELQKERQDLEQQRKQLEAQIA-----ELQSEIAEREEELKELEEQLESL--------------QEELAA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 813 LKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVL 892
Cdd:COG4372 169 LEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1769843730 893 EEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREILAK 936
Cdd:COG4372 249 EELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAA 292
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
618-856 |
5.56e-08 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 56.44 E-value: 5.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 618 MQEDIFENQLKQKELAHMQALAEEWKKRDRERESlvkkKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQS 697
Cdd:pfam07888 47 LQAQEAANRQREKEKERYKRDREQWERQRRELES----RVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 698 ERQRNLQ---ELQDSIRRAKEDCI-HQVELERLK---------IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQN 764
Cdd:pfam07888 123 QRAAHEArirELEEDIKTLTQRVLeRETELERMKerakkagaqRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLA 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 765 NKPE--IRLQSEINLLTL-------EKVELERKLE--SATKSKLHYKQQ----WGRALKELARLKQREQ-ESQMARLKKQ 828
Cdd:pfam07888 203 QRDTqvLQLQDTITTLTQklttahrKEAENEALLEelRSLQERLNASERkvegLGEELSSMAAQRDRTQaELHQARLQAA 282
|
250 260
....*....|....*....|....*...
gi 1769843730 829 QEELEQMRLRYLAAEEKDTVKTERQELL 856
Cdd:pfam07888 283 QLTLQLADASLALREGRARWAQERETLQ 310
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
611-855 |
6.31e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 56.67 E-value: 6.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 611 ELEMWKEMQEDIFENQLKQKELAHMQaLAEEWKKRDREREslvkkkvaEYTILEGKLQKTLIDLEKREQQLaSVESELQR 690
Cdd:pfam15921 332 ELREAKRMYEDKIEELEKQLVLANSE-LTEARTERDQFSQ--------ESGNLDDQLQKLLADLHKREKEL-SLEKEQNK 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 691 E---------------KKELqSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKE 755
Cdd:pfam15921 402 RlwdrdtgnsitidhlRREL-DDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKV 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 756 FQQFKDQQnnkpeIRLQSE---INLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQEsqmarLKKQQEEL 832
Cdd:pfam15921 481 VEELTAKK-----MTLESSertVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDH-----LRNVQTEC 550
|
250 260
....*....|....*....|...
gi 1769843730 833 EQMRLRylAAEEKDTVKTERQEL 855
Cdd:pfam15921 551 EALKLQ--MAEKDKVIEILRQQI 571
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
628-795 |
2.07e-07 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 53.00 E-value: 2.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 628 KQKELAHMQALAEEWKKRDRERESLvKKKVAEytiLEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQR--NLQE 705
Cdd:COG1579 5 DLRALLDLQELDSELDRLEHRLKEL-PAELAE---LEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARikKYEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 706 LQDSIRRAKE--DCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKpEIRLQSEINLLTLEKV 783
Cdd:COG1579 81 QLGNVRNNKEyeALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEK-KAELDEELAELEAELE 159
|
170
....*....|..
gi 1769843730 784 ELERKLESATKS 795
Cdd:COG1579 160 ELEAEREELAAK 171
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
657-881 |
2.46e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.92 E-value: 2.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 657 VAEYTILEGkLQKTLIDLEKREQQLASVEsELQREKKELQseRQRNLQELQDSIRRAKEDcIHQVELERLKIKQLEEDKH 736
Cdd:COG4913 231 VEHFDDLER-AHEALEDAREQIELLEPIR-ELAERYAAAR--ERLAELEYLRAALRLWFA-QRRLELLEAELEELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 737 RLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQseinlltlekvELERKLESATKSKLHYKQQWGRALKELARLKQR 816
Cdd:COG4913 306 RLEAELERLEARLDALREELDELEAQIRGNGGDRLE-----------QLEREIERLERELEERERRRARLEALLAALGLP 374
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 817 EQESQmarlkkqqEELEQMRLRylAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQD-STEIAS 881
Cdd:COG4913 375 LPASA--------EEFAALRAE--AAALLEALEEELEALEEALAEAEAALRDLRRELRElEAEIAS 430
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
673-835 |
2.88e-07 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 54.26 E-value: 2.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 673 DLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDcIHQVELER----LKIKQLEEDKHRLQQQLNDAENK 748
Cdd:pfam05667 307 QFTNEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESS-IQELEKEIkkleSSIKQVEEELEELKEQNEELEKQ 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 749 YKILEKEFQQFKDQQNNkpeirlqseinlltLEKveLERKLESATKSKLHYKQQWG----------RALKELARLKQREQ 818
Cdd:pfam05667 386 YKVKKKTLDLLPDAEEN--------------IAK--LQALVDASAQRLVELAGQWEkhrvplieeyRALKEAKSNKEDES 449
|
170
....*....|....*..
gi 1769843730 819 ESQMARLKKQQEELEQM 835
Cdd:pfam05667 450 QRKLEEIKELREKIKEV 466
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
616-862 |
3.74e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 54.26 E-value: 3.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 616 KEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKEL 695
Cdd:TIGR04523 349 KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 696 QSERQRNLQeLQDSIRRAKEDcIHQVElerLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKpeirlQSEI 775
Cdd:TIGR04523 429 ERLKETIIK-NNSEIKDLTNQ-DSVKE---LIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-----EKEL 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 776 NLLTLEKVELERKLESATK--SKLHYKQ--------QWGRALKELAR-LKQREQESQMARLKKQ----QEELEQMRLRYL 840
Cdd:TIGR04523 499 KKLNEEKKELEEKVKDLTKkiSSLKEKIeklesekkEKESKISDLEDeLNKDDFELKKENLEKEidekNKEIEELKQTQK 578
|
250 260
....*....|....*....|....*..
gi 1769843730 841 AAEEKDTVKTER-----QELLDIRNEL 862
Cdd:TIGR04523 579 SLKKKQEEKQELidqkeKEKKDLIKEI 605
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
644-910 |
8.06e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.05 E-value: 8.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 644 KRDRERESLVKKKVAEY----TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDcIH 719
Cdd:pfam02463 168 KRKKKEALKKLIEETENlaelIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE-LL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 720 QVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELER----------KL 789
Cdd:pfam02463 247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEklkesekekkKA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 790 ESATKSKLHYK--QQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYL---------AAEEKDTVKTERQELLDI 858
Cdd:pfam02463 327 EKELKKEKEEIeeLEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKkleserlssAAKLKEEELELKSEEEKE 406
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1769843730 859 RNELNRLRQQEQKQYQDSTEIASGKKdgphgSVLEEGLDDYLTRLIEERDTL 910
Cdd:pfam02463 407 AQLLLELARQLEDLLKEEKKEELEIL-----EEEEESIELKQGKLTEEKEEL 453
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
597-871 |
1.06e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.67 E-value: 1.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 597 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAE---YTILEGKL---QKT 670
Cdd:pfam02463 243 QELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLerrKVDDEEKLkesEKE 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 671 LIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRakedcihQVELERLKIKQLeeDKHRLQQQLNDAENKYK 750
Cdd:pfam02463 323 KKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKL-------QEKLEQLEEELL--AKKKLESERLSSAAKLK 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 751 ILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKlhykqqwgraLKELARLKQREQESQMARLKKQQE 830
Cdd:pfam02463 394 EEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI----------ELKQGKLTEEKEELEKQELKLLKD 463
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1769843730 831 ELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQK 871
Cdd:pfam02463 464 ELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESK 504
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
595-763 |
1.66e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.08 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 595 EIQTEPRETLEYKAALElEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLvkkkvAEYTILEGKLQKTLIDL 674
Cdd:COG4717 85 EKEEEYAELQEELEELE-EELEELEAELEELREELEKLEKLLQLLPLYQELEALEAEL-----AELPERLEELEERLEEL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 675 EKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEdcihqvELERL--KIKQLEEDKHRLQQQLNDAENKYKIL 752
Cdd:COG4717 159 RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE------ELEELqqRLAELEEELEEAQEELEELEEELEQL 232
|
170
....*....|.
gi 1769843730 753 EKEFQQFKDQQ 763
Cdd:COG4717 233 ENELEAAALEE 243
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
675-872 |
1.75e-06 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 51.88 E-value: 1.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 675 EKREQQLASVESELQREKKelQSERQRnLQELQDSIRRakedcihqVELERlKIKQLEEDKHRLQQQLNDAENKYKILEK 754
Cdd:pfam15709 313 EERSEEDPSKALLEKREQE--KASRDR-LRAERAEMRR--------LEVER-KRREQEEQRRLQQEQLERAEKMREELEL 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 755 EfqqfkdQQNNKPEIRL----QSEINLLTLEKVELERKLESATKSKLHYKQQ-WGRALKELARLKQREQESQMARLKKQQ 829
Cdd:pfam15709 381 E------QQRRFEEIRLrkqrLEEERQRQEEEERKQRLQLQAAQERARQQQEeFRRKLQELQRKKQQEEAERAEAEKQRQ 454
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1769843730 830 EEL------EQMRLRYLAAEEKDTVKTERQELLD-IRNELNRLRQQEQKQ 872
Cdd:pfam15709 455 KELemqlaeEQKRLMEMAEEERLEYQRQKQEAEEkARLEAEERRQKEEEA 504
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
678-875 |
3.42e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 50.79 E-value: 3.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 678 EQQLASVESELQREKKELQSERQRN-LQELQDsirrakedcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEkef 756
Cdd:COG3206 181 EEQLPELRKELEEAEAALEEFRQKNgLVDLSE-----------EAKLLLQQLSELESQLAEARAELAEAEARLAALR--- 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 757 QQFKDQQNNKPEIRLQSEINLLTLEKVELERKL--ESATKSKLHYK-QQWGRALKELARLKQREQESQMARLKKQQEELE 833
Cdd:COG3206 247 AQLGSGPDALPELLQSPVIQQLRAQLAELEAELaeLSARYTPNHPDvIALRAQIAALRAQLQQEAQRILASLEAELEALQ 326
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1769843730 834 QmRLRYLAAEEkDTVKTERQELLDIRNELNRLRQQ---EQKQYQD 875
Cdd:COG3206 327 A-REASLQAQL-AQLEARLAELPELEAELRRLEREvevARELYES 369
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
632-868 |
3.42e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 3.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 632 LAHMQALAEEWKKRDRERESLVKKKvAEYTILEG------KLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQE 705
Cdd:COG4913 224 FEAADALVEHFDDLERAHEALEDAR-EQIELLEPirelaeRYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRA 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 706 lqdsirrakedcihqvelerlKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQnnkpEIRLQSEINLLTLEKVEL 785
Cdd:COG4913 303 ---------------------ELARLEAELERLEARLDALREELDELEAQIRGNGGDR----LEQLEREIERLERELEER 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 786 ERKLESAtksklhykQQWGRALKELARLKQREQESQMARLKKQQEELEQMR--LRYLAAEEKDTVKTERQELLDIRNELN 863
Cdd:COG4913 358 ERRRARL--------EALLAALGLPLPASAEEFAALRAEAAALLEALEEELeaLEEALAEAEAALRDLRRELRELEAEIA 429
|
....*
gi 1769843730 864 RLRQQ 868
Cdd:COG4913 430 SLERR 434
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
624-872 |
3.55e-06 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 50.30 E-value: 3.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 624 ENQLKQKELAHMQALAEEwKKRDRERESLVKKKVAEYTILEGKLQktlidlEKREQQLASVESELQREKKELQSERQRNL 703
Cdd:pfam13868 25 DAQIAEKKRIKAEEKEEE-RRLDEMMEEERERALEEEEEKEEERK------EERKRYRQELEEQIEEREQKRQEEYEEKL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 704 QElqdsiRRAKEDCIHQVELERLKIKQLeedKHRLQQQLNdaenkykileKEFQQFKDQQNNKPEIRLQSEinlltlekV 783
Cdd:pfam13868 98 QE-----REQMDEIVERIQEEDQAEAEE---KLEKQRQLR----------EEIDEFNEEQAEWKELEKEEE--------R 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 784 ELERKLESATKSKLHYKQQWGRALKELARLKQREQE---SQMARLKKQQEELEQMRL-RYLAAEEKDTVKTERQELLDIR 859
Cdd:pfam13868 152 EEDERILEYLKEKAEREEEREAEREEIEEEKEREIArlrAQQEKAQDEKAERDELRAkLYQEEQERKERQKEREEAEKKA 231
|
250
....*....|...
gi 1769843730 860 NELNRLRQQEQKQ 872
Cdd:pfam13868 232 RQRQELQQAREEQ 244
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
571-884 |
3.73e-06 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 50.64 E-value: 3.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 571 SDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWK---EMQEDIFENQLKQKELAHMQALAEE-WKKRD 646
Cdd:pfam02029 25 EEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLDRTAKreeRRQKRLQEALERQKEFDPTIADEKEsVAERK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 647 RERESLVKKKVAEYTILEGKLQKTLID----LEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVE 722
Cdd:pfam02029 105 ENNEEEENSSWEKEEKRDSRLGRYKEEeteiREKEYQENKWSTEVRQAEEEGEEEEDKSEEAEEVPTENFAKEEVKDEKI 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 723 LERLKIKqlEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQS-EINLLTLEKVELERKLESATKS------ 795
Cdd:pfam02029 185 KKEKKVK--YESKVFLDQKRGHPEVKSQNGEEEVTKLKVTTKRRQGGLSQSqEREEEAEVFLEAEQKLEELRRRrqekes 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 796 ----KLHYKQQwgRALKELARLKQREQESQMARlkkqqEELEQMRlrylAAEEKDTVKTERQELLDIRNELNRLRQQ--E 869
Cdd:pfam02029 263 eefeKLRQKQQ--EAELELEELKKKREERRKLL-----EEEEQRR----KQEEAERKLREEEEKRRMKEEIERRRAEaaE 331
|
330
....*....|....*
gi 1769843730 870 QKQYQDSTEIASGKK 884
Cdd:pfam02029 332 KRQKLPEDSSSEGKK 346
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
601-813 |
3.80e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 3.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 601 RETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQ 680
Cdd:COG1196 308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 681 LASVESELQREKKELQS---------ERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKI 751
Cdd:COG1196 388 LLEALRAAAELAAQLEEleeaeeallERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1769843730 752 LEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARL 813
Cdd:COG1196 468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
599-894 |
5.01e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.91 E-value: 5.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 599 EPRETLEYKAALELEMWKEMQEdifENQLKQKelAHMQALAEEWKKRDREreslvKKKVAEYTILEGKLQKTLIDLEKRE 678
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKK---ADEAKKK--AEEAKKADEAKKKAEE-----AKKKADAAKKKAEEAKKAAEAAKAE 1351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 679 QQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELErlkiKQLEEDKHRLQQQLNDAENKYKilekefqq 758
Cdd:PTZ00121 1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAK----KKAEEDKKKADELKKAAAAKKK-------- 1419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 759 fKDQQNNKPEIRLQSEinlltlekvELERKLESATKS-KLHYKQQWGRALKELArlKQREQESQMARLKKQQEELEQMRL 837
Cdd:PTZ00121 1420 -ADEAKKKAEEKKKAD---------EAKKKAEEAKKAdEAKKKAEEAKKAEEAK--KKAEEAKKADEAKKKAEEAKKADE 1487
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1769843730 838 RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEE 894
Cdd:PTZ00121 1488 AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE 1544
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
619-872 |
5.96e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 5.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 619 QEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSE 698
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 699 RQRNLQELQDSIRRAkedcihqvelerLKIKQLEEDKHRLQQQ-LNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINL 777
Cdd:COG4942 99 LEAQKEELAELLRAL------------YRLGRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAE-----ELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 778 LTlekvELERKLESATKSKLHYKQQWGRALKELARLKQrEQESQMARLKKQQEELEQmRLRYLAAEEKdtvkterqellD 857
Cdd:COG4942 162 LA----ALRAELEAERAELEALLAELEEERAALEALKA-ERQKLLARLEKELAELAA-ELAELQQEAE-----------E 224
|
250
....*....|....*
gi 1769843730 858 IRNELNRLRQQEQKQ 872
Cdd:COG4942 225 LEALIARLEAEAAAA 239
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
598-926 |
6.24e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 50.11 E-value: 6.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 598 TEPRETLEYKAALELEMwKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKR 677
Cdd:pfam05483 391 SELEEMTKFKNNKEVEL-EELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHY 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 678 EQQLASVESELQREK----------KELQSERQRNLQELQD---SIRRAKEDCIHQVELERLKIKQLEEdkhrLQQQLND 744
Cdd:pfam05483 470 LKEVEDLKTELEKEKlknieltahcDKLLLENKELTQEASDmtlELKKHQEDIINCKKQEERMLKQIEN----LEEKEMN 545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 745 AENKYKILEKEFQQFKDQ--------QNNKPEIR---LQSEINLLTLEKV--ELERKLESATKSkLHYKQQWGRALKELA 811
Cdd:pfam05483 546 LRDELESVREEFIQKGDEvkckldksEENARSIEyevLKKEKQMKILENKcnNLKKQIENKNKN-IEELHQENKALKKKG 624
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 812 RLKQREQESQMARLKKQQEELEQMRLRYlaAEEKDTVKTE------RQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 885
Cdd:pfam05483 625 SAENKQLNAYEIKVNKLELELASAKQKF--EEIIDNYQKEiedkkiSEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKI 702
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1769843730 886 GPHGSVLEEGLDDYlTRLIEERDTLMrtGVYNHEDRIISEL 926
Cdd:pfam05483 703 AEMVALMEKHKHQY-DKIIEERDSEL--GLYKNKEQEQSSA 740
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
624-750 |
8.73e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.39 E-value: 8.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 624 ENQLKQKELahmQAlAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELqSERQRNL 703
Cdd:PRK12704 52 EAIKKEALL---EA-KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKEL-EQKQQEL 126
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1769843730 704 QELQDSIRRAKEDciHQVELERLKIKQLEEDKHRLqqqLNDAENKYK 750
Cdd:PRK12704 127 EKKEEELEELIEE--QLQELERISGLTAEEAKEIL---LEKVEEEAR 168
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
599-933 |
1.49e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.37 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 599 EPRETLEYKAALELEmwKEMQEDIFENQLKQKelahmqalAEEWKKRDRE--RESLVKKKVAEYTILEGKLQKTLIDLEK 676
Cdd:PTZ00121 1294 EAKKAEEKKKADEAK--KKAEEAKKADEAKKK--------AEEAKKKADAakKKAEEAKKAAEAAKAEAEAAADEAEAAE 1363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 677 REQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERL--------KIKQLEEDKHRLQQQLNDAENK 748
Cdd:PTZ00121 1364 EKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAaaakkkadEAKKKAEEKKKADEAKKKAEEA 1443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 749 YKI--LEKEFQQFKDQQNNKPEIRLQSEINLLTlEKVELERKLESATKSKLHYKQQwGRALKELARLKQREQESQMARLK 826
Cdd:PTZ00121 1444 KKAdeAKKKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEAKKKAEEAKKK-ADEAKKAAEAKKKADEAKKAEEA 1521
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 827 KQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNR---LRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRL 903
Cdd:PTZ00121 1522 KKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeeKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601
|
330 340 350
....*....|....*....|....*....|
gi 1769843730 904 IEERDTLMRTGVYNHEDRIISELDRQIREI 933
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEE 1631
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
680-857 |
1.51e-05 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 46.46 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 680 QLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK---HR----LQQQLNDAENKYKIL 752
Cdd:pfam08614 11 RLLDRTALLEAENAKLQSEPESVLPSTSSSKLSKASPQSASIQSLEQLLAQLREELaelYRsrgeLAQRLVDLNEELQEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 753 EKEFQQfkdqqnnkpeirLQSEINLLTLEKVELERKLESATksklhykqqwgRALKELARLKQReqesqmarlkkQQEEL 832
Cdd:pfam08614 91 EKKLRE------------DERRLAALEAERAQLEEKLKDRE-----------EELREKRKLNQD-----------LQDEL 136
|
170 180
....*....|....*....|....*.
gi 1769843730 833 EQMRLRYLAAEEK-DTVKTERQELLD 857
Cdd:pfam08614 137 VALQLQLNMAEEKlRKLEKENRELVE 162
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
561-909 |
1.54e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.89 E-value: 1.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 561 GLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDI-----FENQLKQKELAHM 635
Cdd:TIGR00606 730 GLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVtimerFQMELKDVERKIA 809
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 636 QALAE-----------EWKKRDRERESLVKKKVAEYTILegklQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQ 704
Cdd:TIGR00606 810 QQAAKlqgsdldrtvqQVNQEKQEKQHELDTVVSKIELN----RKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQ 885
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 705 ELQDSIRRAKE--DCIHQVELERLKIKQLEEDKHRLQQQ----LNDAENKYKILEKEFQQFKDQ---------------Q 763
Cdd:TIGR00606 886 FEEQLVELSTEvqSLIREIKDAKEQDSPLETFLEKDQQEkeelISSKETSNKKAQDKVNDIKEKvknihgymkdienkiQ 965
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 764 NNKPEIRLQSEINLLTLEKvelerKLESATKSKLHYKQQWGRALKELARLKQREQ--ESQMARLKKQQE--ELEQMRLRY 839
Cdd:TIGR00606 966 DGKDDYLKQKETELNTVNA-----QLEECEKHQEKINEDMRLMRQDIDTQKIQERwlQDNLTLRKRENElkEVEEELKQH 1040
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 840 LAAEEKDTVKTERQELLDIRNELNRLRQQE------QKQYQDSTEIASGKKDGPHGSVLEEgldDYLTRLIEERDT 909
Cdd:TIGR00606 1041 LKEMGQMQVLQMKQEHQKLEENIDLIKRNHvlalgrQKGYEKEIKHFKKELREPQFRDAEE---KYREMMIVMRTT 1113
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
624-864 |
1.56e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 48.97 E-value: 1.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 624 ENQLKQKELAHMQALAEewkkrdRERESLVKKKVAEYTILEGK-LQKTLIDLEKRE---QQLASVESELQREKKELQSER 699
Cdd:pfam05557 15 QNEKKQMELEHKRARIE------LEKKASALKRQLDRESDRNQeLQKRIRLLEKREaeaEEALREQAELNRLKKKYLEAL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 700 QRNLQELQDSIRRAKE--DCI--------HQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQ--NNKP 767
Cdd:pfam05557 89 NKKLNEKESQLADAREviSCLknelselrRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQssLAEA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 768 EIRLQseinlltlekvELERKLESATKSKLHYKQqwgrALKELARLKQREQEsqmarLKKQQEELEQMRlrylaaEEKDT 847
Cdd:pfam05557 169 EQRIK-----------ELEFEIQSQEQDSEIVKN----SKSELARIPELEKE-----LERLREHNKHLN------ENIEN 222
|
250
....*....|....*..
gi 1769843730 848 VKTERQELLDIRNELNR 864
Cdd:pfam05557 223 KLLLKEEVEDLKRKLER 239
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
594-881 |
1.98e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.52 E-value: 1.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 594 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKElahmqALAEEWKKRDRERE---SLVKKKVAEYTILEGKLQKT 670
Cdd:PRK03918 487 KVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKA-----EEYEKLKEKLIKLKgeiKSLKKELEKLEELKKKLAEL 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 671 LIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKE--DCIHQVELERLKIKQLEEDKHRLQQQLNDAENK 748
Cdd:PRK03918 562 EKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLElkDAEKELEREEKELKKLEEELDKAFEELAETEKR 641
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 749 YKILEKEFQQFKdQQNNKPEIRLQSEinlltlEKVELERKLEsatksklhykqqwgRALKELARLKQREQESqMARLKKQ 828
Cdd:PRK03918 642 LEELRKELEELE-KKYSEEEYEELRE------EYLELSRELA--------------GLRAELEELEKRREEI-KKTLEKL 699
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1769843730 829 QEELEQMRlryLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQ-YQDSTEIAS 881
Cdd:PRK03918 700 KEELEERE---KAKKELEKLEKALERVEELREKVKKYKALLKERaLSKVGEIAS 750
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
666-884 |
2.07e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 2.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 666 KLQKTLIDLEKREQQLASVESELQREKKELQSErqrnLQELQDSIRRAKEdcihqvelerlKIKQLEEDKHRLQQQLNDA 745
Cdd:COG3883 20 AKQKELSELQAELEAAQAELDALQAELEELNEE----YNELQAELEALQA-----------EIDKLQAEIAEAEAEIEER 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 746 ENKYKilekefQQFKDQQNNKpeiRLQSEINLLT--------LEKVELERKLESATKSKLhyKQQwgRALKELARLKQRE 817
Cdd:COG3883 85 REELG------ERARALYRSG---GSVSYLDVLLgsesfsdfLDRLSALSKIADADADLL--EEL--KADKAELEAKKAE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1769843730 818 QESQMARLKKQQEELEQMRlrylaaEEKDTVKTERQELldirneLNRLRQQEQKQYQDSTEIASGKK 884
Cdd:COG3883 152 LEAKLAELEALKAELEAAK------AELEAQQAEQEAL------LAQLSAEEAAAEAQLAELEAELA 206
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
597-878 |
2.63e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.21 E-value: 2.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 597 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQAlaEEWKKRDRERESL--VKKKVAEYTILEGKLQKTLIDL 674
Cdd:PTZ00121 1582 KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA--EELKKAEEEKKKVeqLKKKEAEEKKKAEELKKAEEEN 1659
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 675 EKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEdcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEK 754
Cdd:PTZ00121 1660 KIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE----AKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEA 1735
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 755 EFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQwgrALKELARLKQREQESQMARLKKQQEELEQ 834
Cdd:PTZ00121 1736 KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE---ELDEEDEKRRMEVDKKIKDIFDNFANIIE 1812
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1769843730 835 --MRLRYLAAEEKDTVKTERQELLDIRN-ELNRLRQQEQKQYQDSTE 878
Cdd:PTZ00121 1813 ggKEGNLVINDSKEMEDSAIKEVADSKNmQLEEADAFEKHKFNKNNE 1859
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
594-871 |
2.70e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.97 E-value: 2.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 594 SEIQTEPRETLEYKAALELEMWKEMQEDIfeNQLKQKELAHMQALaEEWKKRDRERESLVKKKVAEYTILEGKLQKTlid 673
Cdd:pfam07888 110 SEELSEEKDALLAQRAAHEARIRELEEDI--KTLTQRVLERETEL-ERMKERAKKAGAQRKEEEAERKQLQAKLQQT--- 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 674 lekrEQQLASVESELQrEKKELQSERQRNLQELQDSIRRA--KEDCIHQVELERlkiKQLEEDKHRLQQQLNDAENKYKI 751
Cdd:pfam07888 184 ----EEELRSLSKEFQ-ELRNSLAQRDTQVLQLQDTITTLtqKLTTAHRKEAEN---EALLEELRSLQERLNASERKVEG 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 752 LEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVELERKLESATKSKLHYKQQWG---------------RALK---ELARL 813
Cdd:pfam07888 256 LGEELSSMAAQRD-----RTQAELHQARLQAAQLTLQLADASLALREGRARWAqeretlqqsaeadkdRIEKlsaELQRL 330
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1769843730 814 KQREQESQMARLKKQQE-----------------ELEQMR--LRyLAAEEKDTVKTERQELLDirnelnRLRQQEQK 871
Cdd:pfam07888 331 EERLQEERMEREKLEVElgrekdcnrvqlsesrrELQELKasLR-VAQKEKEQLQAEKQELLE------YIRQLEQR 400
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
609-868 |
3.29e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.81 E-value: 3.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 609 ALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKlQKTLIDL----EKREQQLASV 684
Cdd:pfam15921 437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESS-ERTVSDLtaslQEKERAIEAT 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 685 ESELQRekkeLQSERQRNLQELQ------DSIRRAKEDCihqvelERLKIKQLEEDK--HRLQQQLndaENKYKILEKEF 756
Cdd:pfam15921 516 NAEITK----LRSRVDLKLQELQhlknegDHLRNVQTEC------EALKLQMAEKDKviEILRQQI---ENMTQLVGQHG 582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 757 QQFKDQQNNKPEirLQSEINLLTLEKVELerklesatksklhykqqwgRALKELARLKQREQESQMARLkkqqeELEQMR 836
Cdd:pfam15921 583 RTAGAMQVEKAQ--LEKEINDRRLELQEF-------------------KILKDKKDAKIRELEARVSDL-----ELEKVK 636
|
250 260 270
....*....|....*....|....*....|....*....
gi 1769843730 837 LRYLAAEEKDTVKTERQELLDI-------RNELNRLRQQ 868
Cdd:pfam15921 637 LVNAGSERLRAVKDIKQERDQLlnevktsRNELNSLSED 675
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
653-932 |
3.49e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.20 E-value: 3.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 653 VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRrakedcihQVELERLKIKQLE 732
Cdd:COG4372 8 VGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEE--------ELEQARSELEQLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 733 EDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELAR 812
Cdd:COG4372 80 EELEELNEQLQAAQAELAQAQEELESLQEEAE-----ELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 813 LkqreqESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVL 892
Cdd:COG4372 155 L-----EEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEA 229
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1769843730 893 EEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIRE 932
Cdd:COG4372 230 KLGLALSALLDALELEEDKEELLEEVILKEIEELELAILV 269
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
657-834 |
3.55e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.47 E-value: 3.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 657 VAEYTILEGKLQKTLIDLEKREQQLasveseLQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEdkh 736
Cdd:PRK12704 19 VIGYFVRKKIAEAKIKEAEEEAKRI------LEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK--- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 737 RLQQqlndaenKYKILEKefqqfKDQQNNKPEIRLQSEINLLTLEKVELERKLESAtkSKLHYKQQwgRALKELARLKQR 816
Cdd:PRK12704 90 RLLQ-------KEENLDR-----KLELLEKREEELEKKEKELEQKQQELEKKEEEL--EELIEEQL--QELERISGLTAE 153
|
170
....*....|....*...
gi 1769843730 817 EQESQMarLKKQQEELEQ 834
Cdd:PRK12704 154 EAKEIL--LEKVEEEARH 169
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
698-868 |
3.66e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.74 E-value: 3.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 698 ERQRNLQELQDSIRRAKEDC-IHQVELERLK---------IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkp 767
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIaELEKALAELRkeleeleeeLEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA--- 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 768 eiRLQSEINLLTLEKVELERKLESATKsklhykqqwgrALKELARLKQrEQESQMARLkkqQEELEQMRLRYLAAEEKdt 847
Cdd:TIGR02168 751 --QLSKELTELEAEIEELEERLEEAEE-----------ELAEAEAEIE-ELEAQIEQL---KEELKALREALDELRAE-- 811
|
170 180
....*....|....*....|.
gi 1769843730 848 VKTERQELLDIRNELNRLRQQ 868
Cdd:TIGR02168 812 LTLLNEEAANLRERLESLERR 832
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
607-785 |
3.69e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 3.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 607 KAALELEMWKEMQE--DIFENQLKQKEL-AHMQALAEEWKKRDRERESLVKKKVAeytiLEGKLQKTLIDLEKRE-QQLA 682
Cdd:COG4913 266 AARERLAELEYLRAalRLWFAQRRLELLeAELEELRAELARLEAELERLEARLDA----LREELDELEAQIRGNGgDRLE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 683 SVESELQREKKELQsERQRNLQELQDSIR--------------RAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENK 748
Cdd:COG4913 342 QLEREIERLERELE-ERERRRARLEALLAalglplpasaeefaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1769843730 749 YKILEKEFQQFKDQQNNKPE--IRLQSEIN-LLTLEKVEL 785
Cdd:COG4913 421 LRELEAEIASLERRKSNIPArlLALRDALAeALGLDEAEL 460
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
647-900 |
3.90e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 47.73 E-value: 3.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 647 RERESLVKKKVAEYTILEGK--LQKTLIDLEKRE-----QQLASVESELQREKKELqsERQRNLQELQDSIRRAKEDCIH 719
Cdd:TIGR00606 712 KSTESELKKKEKRRDEMLGLapGRQSIIDLKEKEipelrNKLQKVNRDIQRLKNDI--EEQETLLGTIMPEEESAKVCLT 789
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 720 QVELERLKIKQLEEDKHRLQQQLndAENKYKILEKEFQQFKDQQNNKpeirlQSEINLLTlEKVELERKLESATKSKLHY 799
Cdd:TIGR00606 790 DVTIMERFQMELKDVERKIAQQA--AKLQGSDLDRTVQQVNQEKQEK-----QHELDTVV-SKIELNRKLIQDQQEQIQH 861
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 800 KQQWGRALK----ELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQD 875
Cdd:TIGR00606 862 LKSKTNELKseklQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQD 941
|
250 260 270
....*....|....*....|....*....|.
gi 1769843730 876 STEIASGKKDGPHG------SVLEEGLDDYL 900
Cdd:TIGR00606 942 KVNDIKEKVKNIHGymkdieNKIQDGKDDYL 972
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
629-912 |
4.19e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.66 E-value: 4.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 629 QKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQktlidLEKREQQLASVESELQREKKELQSERQRNLQELQD 708
Cdd:TIGR00618 552 TSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQN-----ITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 709 SIRRAKEDCIHQVELErlkikQLEEDKHRLQQQLNDAENKYKILE-KEFQQFKDQQNNKPEIRLQSEINLLTLEKVELER 787
Cdd:TIGR00618 627 LQDVRLHLQQCSQELA-----LKLTALHALQLTLTQERVREHALSiRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQ 701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 788 K-------LESATKSKLHYKQQWGRALKELARLKQRE----------QESQMARLKKQQEELEQMRLRYLAAEEKDtvkT 850
Cdd:TIGR00618 702 CqtllrelETHIEEYDREFNEIENASSSLGSDLAAREdalnqslkelMHQARTVLKARTEAHFNNNEEVTAALQTG---A 778
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1769843730 851 ERQELldIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMR 912
Cdd:TIGR00618 779 ELSHL--AAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLE 838
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
595-874 |
5.17e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 47.12 E-value: 5.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 595 EIQTEPRETLEYKAALELEMwKEMQE--DIFENQLKQKE------LAHMQALAEEWKKRDRERESL---VKKKVAEYTIL 663
Cdd:pfam10174 458 QREREDRERLEELESLKKEN-KDLKEkvSALQPELTEKEsslidlKEHASSLASSGLKKDSKLKSLeiaVEQKKEECSKL 536
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 664 EGKLQKTlidlekreQQLASVEselqREKKELqSERQRNLQelQDSIRRAKEDCIHQVELERL--KIKQLEEDKHrlqqq 741
Cdd:pfam10174 537 ENQLKKA--------HNAEEAV----RTNPEI-NDRIRLLE--QEVARYKEESGKAQAEVERLlgILREVENEKN----- 596
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 742 lnDAENKYKILEK-EFQQFKDQQNNKPEIR-LQSEINLLTLEKVELERKLESATKSKlHYKQQWGRALKELARLKQrEQE 819
Cdd:pfam10174 597 --DKDKKIAELESlTLRQMKEQNKKVANIKhGQQEMKKKGAQLLEEARRREDNLADN-SQQLQLEELMGALEKTRQ-ELD 672
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 820 SQMARL---------------------KKQQEELEQMRLRYL--AAEEKDT-----------VKTERQELLDIRNELNRL 865
Cdd:pfam10174 673 ATKARLsstqqslaekdghltnlraerRKQLEEILEMKQEALlaAISEKDAniallelssskKKKTQEEVMALKREKDRL 752
|
....*....
gi 1769843730 866 RQQEQKQYQ 874
Cdd:pfam10174 753 VHQLKQQTQ 761
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
639-910 |
5.22e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 47.34 E-value: 5.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 639 AEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESEL------------QREK-----KELQSERQR 701
Cdd:PRK02224 344 AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIeelrerfgdapvDLGNaedflEELREERDE 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 702 ----------NLQELQDSIRRAK------------------------EDCIHQVELERLKIKQLEEDKHRLQQQLNDAEn 747
Cdd:PRK02224 424 lrereaeleaTLRTARERVEEAEalleagkcpecgqpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAE- 502
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 748 KYKILEKEFQQFKDQQNNKPEIRLQSEINL---------LTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ 818
Cdd:PRK02224 503 DLVEAEDRIERLEERREDLEELIAERRETIeekreraeeLRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA 582
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 819 EsqmarLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELN------------RLRQQEQKQYQDSTEIASGKKDg 886
Cdd:PRK02224 583 E-----LKERIESLERIRTLLAAIADAEDEIERLREKREALAELNderrerlaekreRKRELEAEFDEARIEEAREDKE- 656
|
330 340
....*....|....*....|....
gi 1769843730 887 pHGSVLEEGLDDYLTRLIEERDTL 910
Cdd:PRK02224 657 -RAEEYLEQVEEKLDELREERDDL 679
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
594-941 |
5.24e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.42 E-value: 5.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 594 SEIQTEPRETLEyKAALELEMWKEMQEDIFEN------QLKQKELAHMQALAEEWK----------KRDRERESLvkkKV 657
Cdd:pfam15921 137 SQSQEDLRNQLQ-NTVHELEAAKCLKEDMLEDsntqieQLRKMMLSHEGVLQEIRSilvdfeeasgKKIYEHDSM---ST 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 658 AEYTILEGKLQKTLIDLEKR----EQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDciHQVELERLKIK---- 729
Cdd:pfam15921 213 MHFRSLGSAISKILRELDTEisylKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISE--HEVEITGLTEKassa 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 730 ---------QLE--EDKHRLQ-----QQLNDAENKYKILEKEFQQFKDQQNNKPEiRLQSEINLLTLEKVE--LERKLES 791
Cdd:pfam15921 291 rsqansiqsQLEiiQEQARNQnsmymRQLSDLESTVSQLRSELREAKRMYEDKIE-ELEKQLVLANSELTEarTERDQFS 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 792 ATKSKLHYKQQwgralKELARLKQREQEsqmARLKKQQEEleqmRLRYLAAEEKDTVKTERQELLDIRNELNRL------ 865
Cdd:pfam15921 370 QESGNLDDQLQ-----KLLADLHKREKE---LSLEKEQNK----RLWDRDTGNSITIDHLRRELDDRNMEVQRLeallka 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 866 -RQQEQKQYQDSTEIASGKKDGPHG----SVLEEGLDDYLTRLIEERdTLMRTGVYNHEdRIISELDRQIREILAKSNAS 940
Cdd:pfam15921 438 mKSECQGQMERQMAAIQGKNESLEKvsslTAQLESTKEMLRKVVEEL-TAKKMTLESSE-RTVSDLTASLQEKERAIEAT 515
|
.
gi 1769843730 941 N 941
Cdd:pfam15921 516 N 516
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
598-872 |
6.11e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.09 E-value: 6.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 598 TEPRETLEYKAALELEMWKEMQED---IFENQLKQKELAHMQA---LAEEWKKRDRERESLVKKKVAeytiLEGKLQKTL 671
Cdd:pfam01576 315 TAAQQELRSKREQEVTELKKALEEetrSHEAQLQEMRQKHTQAleeLTEQLEQAKRNKANLEKAKQA----LESENAELQ 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 672 IDLekREQQLASVESELQREKKELQ----------SERQRnlQELQDSIRRAkedcihQVELERLK--IKQLEEDKHRLQ 739
Cdd:pfam01576 391 AEL--RTLQQAKQDSEHKRKKLEGQlqelqarlseSERQR--AELAEKLSKL------QSELESVSslLNEAEGKNIKLS 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 740 QQLNDAENKYKILEKEFQQFKDQQNNkpeirLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQE 819
Cdd:pfam01576 461 KDVSSLESQLQDTQELLQEETRQKLN-----LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEE 535
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1769843730 820 SQMA------RLKKQQEELEQMRLRY----LAAEEKDTVKTE-RQELLDIRNELNRLRQ----QEQKQ 872
Cdd:pfam01576 536 DAGTlealeeGKKRLQRELEALTQQLeekaAAYDKLEKTKNRlQQELDDLLVDLDHQRQlvsnLEKKQ 603
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
655-875 |
6.18e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.93 E-value: 6.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 655 KKVAEYtilegKLQKTLIDLEKREQQLASVESELQREKKELQSERQRnLQELQDSIRRakedcihQVELERLKIKQLEED 734
Cdd:COG3206 196 AALEEF-----RQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAE-AEARLAALRA-------QLGSGPDALPELLQS 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 735 KH--RLQQQLNDAENKYKILEKEFqqfkdqQNNKPEIR-LQSEINlltlekvELERKLESATksklhyKQQWGRALKELA 811
Cdd:COG3206 263 PViqQLRAQLAELEAELAELSARY------TPNHPDVIaLRAQIA-------ALRAQLQQEA------QRILASLEAELE 323
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 812 RLKQREQE--SQMARLKKQQEELEQMRLRYLAAEEKdtVKTERQELLDIRNELNRLRQQEQKQYQD 875
Cdd:COG3206 324 ALQAREASlqAQLAQLEARLAELPELEAELRRLERE--VEVARELYESLLQRLEEARLAEALTVGN 387
|
|
| CEP63 |
pfam17045 |
Centrosomal protein of 63 kDa; CEP63 is a family of eukaryotic proteins involved in centriole ... |
617-872 |
6.23e-05 |
|
Centrosomal protein of 63 kDa; CEP63 is a family of eukaryotic proteins involved in centriole activity.
Pssm-ID: 465338 [Multi-domain] Cd Length: 264 Bit Score: 45.58 E-value: 6.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 617 EMQE-----DIFENQLKQKELAHMQALaeEWKKRDRERESLVKKKVAEYTILE-GKLQKTLIDLE--------KREQQLA 682
Cdd:pfam17045 7 ELQElmkqiDIMVAHKKSEWEGQTRAL--ETRLDIREEELLSARNTLERKHKEiGLLRQQLEELEkgkqelvaKYEQQLQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 683 SVESELQREKKELQSERQRNLQELQDSIRRAKEDcihQVELERLKIKQ-------LEEDKHRL--QQQLNDAENKYKILE 753
Cdd:pfam17045 85 KLQEELSKLKRSYEKLQRKQLKEAREEAKSREED---RSELSRLNGKLeefrqksLEWEQQRLqyQQQVASLEAQRKALA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 754 KEFQQFK-----DQQNNKPEI--RLQSEINLLTlekveleRKLESATKSkLHykqqwgralkelarlkqreqesqmarlk 826
Cdd:pfam17045 162 EQSSLIQsaayqVQLEGRKQCleASQSEIQRLR-------SKLERAQDS-LC---------------------------- 205
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 827 kqQEELEQMRLRYLAAEEKDTVKT---ERQELLD-----------IRNELNRLRQQEQKQ 872
Cdd:pfam17045 206 --AQELELERLRMRVSELGDSNRKlleEQQRLLEelrmsqrqlqvLQNELMELKATLQSQ 263
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
638-831 |
7.37e-05 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 46.48 E-value: 7.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 638 LAEEWKKRDRERESLVKKKVAEytiLEGKLQKtliDLEKREQQLASVESElQREKKELQSERQRNLQELQDSIRRAKEDC 717
Cdd:pfam15709 328 REQEKASRDRLRAERAEMRRLE---VERKRRE---QEEQRRLQQEQLERA-EKMREELELEQQRRFEEIRLRKQRLEEER 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 718 IHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQfKDQQNNKPEIRLQSEINLLTLEkvELERKLESATKSKL 797
Cdd:pfam15709 401 QRQEEEERKQRLQLQAAQERARQQQEEFRRKLQELQRKKQQ-EEAERAEAEKQRQKELEMQLAE--EQKRLMEMAEEERL 477
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1769843730 798 HYKQQWGRAlKELARLK---QREQESQMARL-----KKQQEE 831
Cdd:pfam15709 478 EYQRQKQEA-EEKARLEaeeRRQKEEEAARLaleeaMKQAQE 518
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
677-844 |
8.09e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 46.87 E-value: 8.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 677 REQQLASVESELQrEKKELQSERQRNLQELQdsirRAKEDcihqveLERLKIKQL--------EEDKHRLQQQLNDAENK 748
Cdd:PRK04863 784 REKRIEQLRAERE-ELAERYATLSFDVQKLQ----RLHQA------FSRFIGSHLavafeadpEAELRQLNRRRVELERA 852
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 749 YKILEKEFQQFKDQ-QNNKPEI----RLQSEINLL---TLEK--VELERKLESATKSKLhYKQQWGRALKELarlkqreq 818
Cdd:PRK04863 853 LADHESQEQQQRSQlEQAKEGLsalnRLLPRLNLLadeTLADrvEEIREQLDEAEEAKR-FVQQHGNALAQL-------- 923
|
170 180
....*....|....*....|....*.
gi 1769843730 819 ESQMARLKKQQEELEQMRLRYLAAEE 844
Cdd:PRK04863 924 EPIVSVLQSDPEQFEQLKQDYQQAQQ 949
|
|
| Granin |
pfam01271 |
Granin (chromogranin or secretogranin); |
594-897 |
9.50e-05 |
|
Granin (chromogranin or secretogranin);
Pssm-ID: 279595 [Multi-domain] Cd Length: 584 Bit Score: 46.18 E-value: 9.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 594 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQ-ALAEEWKKRDRERESLVKKKVAEYTilegklQKTLI 672
Cdd:pfam01271 98 NEPGGHSRENQPYALQVEKEFKTDHSDDYETQQWEEEKLKHMRfPLRYEENSEEKHSEREGELSEVFEN------PRSQA 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 673 DLEKREQQLASVESElQREKKELQSERQRNLQELQDSIRRAKEdciHQVELERLKIKQlEEDKHRLQQQLNDAENKYKIL 752
Cdd:pfam01271 172 TLKKVFEEVSRLDTP-SKQKREKSDEREKSSQESGEDTYRQEN---IPQEDQVGPEDQ-EPSEEGEEDATQEEVKRSRPR 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 753 EKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQ--QE 830
Cdd:pfam01271 247 THHGRSLPDESSRGGQLGLEEEASEEEEEYGEESRGLSAVQTYLLRLVNARGRGRSEKRAERERSEESEEEELKRAspYE 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 831 ELEQMRLRYL--AAEEKDTVKTERQ-----------ELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLD 897
Cdd:pfam01271 327 ELEITANLQIppSEEERMLKKAGRSprgrvdeagalEALEALEEKRKLDLDHSRVFESSEDGAPRAPQGAWVEALRNYLS 406
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
738-870 |
1.11e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.16 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 738 LQQQLNDAENKYKILEKEFQQFKdQQNNkpEIRLQSEINLLTLEKVELERKLESAT------KSKLHY-KQQWGRALKEL 810
Cdd:COG3206 180 LEEQLPELRKELEEAEAALEEFR-QKNG--LVDLSEEAKLLLQQLSELESQLAEARaelaeaEARLAAlRAQLGSGPDAL 256
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1769843730 811 ARLKQREQESQM-ARLKKQQEELEQMRLRYLAA--------EEKDTVKTERQE-----LLDIRNELNRLRQQEQ 870
Cdd:COG3206 257 PELLQSPVIQQLrAQLAELEAELAELSARYTPNhpdvialrAQIAALRAQLQQeaqriLASLEAELEALQAREA 330
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
593-906 |
1.20e-04 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 45.90 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 593 PSEIqtePRETLEYKAALELEMWKEMQED-------IFENQLKQKELAHMQALAEEWKKR-----DRERESLVKKKVAEY 660
Cdd:pfam07111 232 PPEV---HSQTWELERQELLDTMQHLQEDradlqatVELLQVRVQSLTHMLALQEEELTRkiqpsDSLEPEFPKKCRSLL 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 661 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQElQDSIRRAKEDCIHQVELERLKIKQL-------EE 733
Cdd:pfam07111 309 NRWREKVFALMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQE-QAILQRALQDKAAEVEVERMSAKGLqmelsraQE 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 734 DKHRLQQQLNDAENKYKI-----------LEKEFQQFKDQQNNKPE--------IRLQSEINLLTLEKVELER-KLESAT 793
Cdd:pfam07111 388 ARRRQQQQTASAEEQLKFvvnamsstqiwLETTMTRVEQAVARIPSlsnrlsyaVRKVHTIKGLMARKVALAQlRQESCP 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 794 KSKL-------------HYKQQWGRALKEL---ARLKQreQESQMARlkkQQEELEQMRLRYLAAEEKDTVKTERQELLD 857
Cdd:pfam07111 468 PPPPappvdadlsleleQLREERNRLDAELqlsAHLIQ--QEVGRAR---EQGEAERQQLSEVAQQLEQELQRAQESLAS 542
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1769843730 858 IRNELNRLRQQEQKQYQDSTEIAS--GKKDGPHGSVLEEGLDDYLTRLIEE 906
Cdd:pfam07111 543 VGQQLEVARQGQQESTEEAASLRQelTQQQEIYGQALQEKVAEVETRLREQ 593
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
607-789 |
1.21e-04 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 45.44 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 607 KAALELEMwKEMQED-------IFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTI----LEGKLQKTLIDLE 675
Cdd:pfam15742 153 KKQLEERI-KEASENeaklkqqYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSQQQLriqqQEAQLKQLENEKR 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 676 KREQQLASVE------SELQREKKELQSERQRNLQELQDSIR--------------RAKEDCIHQVELERLKIKQLEEDK 735
Cdd:pfam15742 232 KSDEHLKSNQelseklSSLQQEKEALQEELQQVLKQLDVHVRkynekhhhhkaklrRAKDRLVHEVEQRDERIKQLENEI 311
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1769843730 736 HRLQQQLNdaenkykiLEKEFQQFKDQQNNKpeirlqseinlLTLEKVELERKL 789
Cdd:pfam15742 312 GILQQQSE--------KEKAFQKQVTAQNEI-----------LLLEKRKLLEQL 346
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
601-880 |
1.48e-04 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 44.91 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 601 RETLEYKAALELEMWKEMQEDIF-----ENQLKQKELAHMQALAEEWKKRDRERESlvkkkvaeytilegKLQKTLIDLE 675
Cdd:pfam13868 36 AEEKEEERRLDEMMEEERERALEeeeekEEERKEERKRYRQELEEQIEEREQKRQE--------------EYEEKLQERE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 676 KREQQLASVESELQREKKELQSERQRNLQELQDSIR---RAKEDCIHQVELERLKIKQLEEDKHRLQQQLnDAENKYKIL 752
Cdd:pfam13868 102 QMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEeqaEWKELEKEEEREEDERILEYLKEKAEREEER-EAEREEIEE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 753 EKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELErklesatksklhYKQQWGRALKELARLKQREQESQMARLKKQQEEL 832
Cdd:pfam13868 181 EKEREIARLRAQQEKAQDEKAERDELRAKLYQEE------------QERKERQKEREEAEKKARQRQELQQAREEQIELK 248
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1769843730 833 EQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIA 880
Cdd:pfam13868 249 ERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELE 296
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
674-871 |
1.53e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 45.62 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 674 LEKREQQLASVESELQREK---KELQSERQRNLQELQDSIRRAKEDCIH------QVELERLKiKQLEEDKHRLQQ-QLN 743
Cdd:pfam06160 181 LEKLEEETDALEELMEDIPplyEELKTELPDQLEELKEGYREMEEEGYAlehlnvDKEIQQLE-EQLEENLALLENlELD 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 744 DAENK-----------YKILEKEFQQFKDQQNNKPEIRlqSEINLLTLEKVELERKLEsatksklHYKQQWGRALKELAR 812
Cdd:pfam06160 260 EAEEAleeieeridqlYDLLEKEVDAKKYVEKNLPEIE--DYLEHAEEQNKELKEELE-------RVQQSYTLNENELER 330
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 813 lkQREQESQMARLKKQQEELEQ-----------MRLRYLAAEEKDTVKTERQEllDIRNELNRLRQQEQK 871
Cdd:pfam06160 331 --VRGLEKQLEELEKRYDEIVErleekevayseLQEELEEILEQLEEIEEEQE--EFKESLQSLRKDELE 396
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
666-885 |
1.66e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.40 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 666 KLQKTLIDLEKREQQLASVES---ELQREKKELQSERQRNLQELQDsirraKEDCIHQVELERLK-------IKQLEEDK 735
Cdd:TIGR04523 139 NIDKFLTEIKKKEKELEKLNNkynDLKKQKEELENELNLLEKEKLN-----IQKNIDKIKNKLLKlelllsnLKKKIQKN 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 736 HRLQQQLNDAENKYKILEKEFQQfkdqqnnkpeirLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQ 815
Cdd:TIGR04523 214 KSLESQISELKKQNNQLKDNIEK------------KQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNK 281
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1769843730 816 R--EQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNrlrQQEQKQYQDSTEIASGKKD 885
Cdd:TIGR04523 282 KikELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQIS---QNNKIISQLNEQISQLKKE 350
|
|
| CCDC34 |
pfam13904 |
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ... |
623-767 |
1.68e-04 |
|
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.
Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 43.93 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 623 FENQLKQKELAHMQ-ALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESElQREKKELQSERQR 701
Cdd:pfam13904 57 YENWLAAKQRQRQKeLQAQKEEREKEEQEAELRKRLAKEKYQEWLQRKARQQTKKREESHKQKAAE-SASKSLAKPERKV 135
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 702 nlqeLQDSIRRAKEDCIhQVELERLKIKQLEEDKHRLQQQLNDAENKyKILEKEFQQFKDQQNNKP 767
Cdd:pfam13904 136 ----SQEEAKEVLQEWE-RKKLEQQQRKREEEQREQLKKEEEEQERK-QLAEKAWQKWMKNVKNKP 195
|
|
| C2 |
pfam00168 |
C2 domain; |
9-114 |
1.70e-04 |
|
C2 domain;
Pssm-ID: 425499 [Multi-domain] Cd Length: 104 Bit Score: 41.54 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 9 LIVVSILEGRHFPKRPKHMLV---VEAKFDGEQ--LATDPVDHTDQPEFATELAWEIdrkalhqHRLQRTPIKLQCFALD 83
Cdd:pfam00168 2 RLTVTVIEAKNLPPKDGNGTSdpyVKVYLLDGKqkKKTKVVKNTLNPVWNETFTFSV-------PDPENAVLEIEVYDYD 74
|
90 100 110
....*....|....*....|....*....|.
gi 1769843730 84 pVTSAKETIGYIVLDLRTAQETKQAPKWYQL 114
Cdd:pfam00168 75 -RFGRDDFIGEVRIPLSELDSGEGLDGWYPL 104
|
|
| CCDC34 |
pfam13904 |
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several ... |
668-844 |
2.07e-04 |
|
Coiled-coil domain-containing protein 3; This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.
Pssm-ID: 464032 [Multi-domain] Cd Length: 221 Bit Score: 43.54 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 668 QKTLIDLEKREQQLASVESELQREKKELQSERQRNLQElqdsirRAKEDcihqvelerlkikQLEEDKHRLqqqlndAEN 747
Cdd:pfam13904 41 ARKLEGLKLERQPLEAYENWLAAKQRQRQKELQAQKEE------REKEE-------------QEAELRKRL------AKE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 748 KYK--ILEKEFQQFKDQQNNKPeirlQSEINLLTLEKVELERKlESATKSKLHYKQQWgraLKELARLKQREQESQMARL 825
Cdd:pfam13904 96 KYQewLQRKARQQTKKREESHK----QKAAESASKSLAKPERK-VSQEEAKEVLQEWE---RKKLEQQQRKREEEQREQL 167
|
170
....*....|....*....
gi 1769843730 826 KKQQEELEQMRLRYLAAEE 844
Cdd:pfam13904 168 KKEEEEQERKQLAEKAWQK 186
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
687-885 |
2.09e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 44.89 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 687 ELQREKKELQSER---QRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILE-------KEF 756
Cdd:pfam07888 38 ECLQERAELLQAQeaaNRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSasseelsEEK 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 757 QQFKDQQ-NNKPEIR-LQSEINLLTLEKVELERKLESATKsklhykqqwgRALKELARLKQREQESQMARLKKQQEELEQ 834
Cdd:pfam07888 118 DALLAQRaAHEARIReLEEDIKTLTQRVLERETELERMKE----------RAKKAGAQRKEEEAERKQLQAKLQQTEEEL 187
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1769843730 835 MRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 885
Cdd:pfam07888 188 RSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEE 238
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
557-910 |
2.16e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.34 E-value: 2.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 557 LEDYGLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPretlEYKAALELEMwKEMQEDIFENQLKQKELAHMQ 636
Cdd:TIGR00618 175 LDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYH----ERKQVLEKEL-KHLREALQQTQQSHAYLTQKR 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 637 ALAEEWKKRDRERESLVKKkVAEYTILEGKLQKTLIDLEKR----------------EQQLASVESELQREKKELQSERQ 700
Cdd:TIGR00618 250 EAQEEQLKKQQLLKQLRAR-IEELRAQEAVLEETQERINRArkaaplaahikavtqiEQQAQRIHTELQSKMRSRAKLLM 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 701 R---------NLQELQDSIRRAKEDCIH----------------QVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKE 755
Cdd:TIGR00618 329 KraahvkqqsSIEEQRRLLQTLHSQEIHirdahevatsireiscQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQRE 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 756 F--QQFKDQQNNKPEIRL---------------------QSEINLLTLEKVELE------RKLESATKSKLHYKQQWGRA 806
Cdd:TIGR00618 409 QatIDTRTSAFRDLQGQLahakkqqelqqryaelcaaaiTCTAQCEKLEKIHLQesaqslKEREQQLQTKEQIHLQETRK 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 807 LKELARLKQREQESQmARLKKQQEELEQ---------------MRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQK 871
Cdd:TIGR00618 489 KAVVLARLLELQEEP-CPLCGSCIHPNParqdidnpgpltrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQE 567
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1769843730 872 QYQDSTEIA----SGKKDGPHGSVLEEGLDDYLTRLIEERDTL 910
Cdd:TIGR00618 568 IQQSFSILTqcdnRSKEDIPNLQNITVRLQDLTEKLSEAEDML 610
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
663-845 |
2.47e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.44 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 663 LEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRnLQELQDSIRRAKEdcihqvELERLKiKQLEEDKHRLQQQL 742
Cdd:COG3883 21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-LEALQAEIDKLQA------EIAEAE-AEIEERREELGERA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 743 NDAenkYK----------ILE-KEFQQFKDQ---------QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQ 802
Cdd:COG3883 93 RAL---YRsggsvsyldvLLGsESFSDFLDRlsalskiadADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1769843730 803 wgraLKELARlKQREQESQMARLKKQQEELEQMRLRYLAAEEK 845
Cdd:COG3883 170 ----KAELEA-QQAEQEALLAQLSAEEAAAEAQLAELEAELAA 207
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
653-825 |
2.51e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 2.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 653 VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQS-ERQRNLQELQDSIRRAKE------DCIHQVELER 725
Cdd:COG4717 76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKlEKLLQLLPLYQELEALEAelaelpERLEELEERL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 726 LKIKQLEEDKHRLQQQLNDAENKykiLEKEFQQFkDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGR 805
Cdd:COG4717 156 EELRELEEELEELEAELAELQEE---LEELLEQL-SLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231
|
170 180
....*....|....*....|
gi 1769843730 806 ALKELARLKQREQESQMARL 825
Cdd:COG4717 232 LENELEAAALEERLKEARLL 251
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
674-864 |
2.69e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 44.70 E-value: 2.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 674 LEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEdkhRLQQQLNDAENKYKile 753
Cdd:PRK12705 25 LKKRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEE---RLVQKEEQLDARAE--- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 754 kefqqfkdqqnnkpeirlqsEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEElE 833
Cdd:PRK12705 99 --------------------KLDNLENQLEEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLDAELE-E 157
|
170 180 190
....*....|....*....|....*....|.
gi 1769843730 834 QMRLRYLAAEEKDTVKTERQELLDIRNELNR 864
Cdd:PRK12705 158 EKAQRVKKIEEEADLEAERKAQNILAQAMQR 188
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
678-878 |
2.71e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 45.04 E-value: 2.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 678 EQQLASVESELQREKKELQSERQRnLQELQDSIrrakedcihqvelerLKIKQLEEDKHRlqqQLNDAENKYKILEKEFQ 757
Cdd:PRK10929 108 EQEILQVSSQLLEKSRQAQQEQDR-AREISDSL---------------SQLPQQQTEARR---QLNEIERRLQTLGTPNT 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 758 QFKDQQNnkpeIRLQSEINLLTLEKVELERKLESAtksklHYKQqwgralkELARLkqreqesQMARLKKQQEELEQmrl 837
Cdd:PRK10929 169 PLAQAQL----TALQAESAALKALVDELELAQLSA-----NNRQ-------ELARL-------RSELAKKRSQQLDA--- 222
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1769843730 838 rylaaeekdtvkterqELLDIRNELNRLRQQEQKQYQDSTE 878
Cdd:PRK10929 223 ----------------YLQALRNQLNSQRQREAERALESTE 247
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
661-934 |
2.80e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.93 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 661 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDkhrlqq 740
Cdd:COG1196 581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE------ 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 741 QLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQES 820
Cdd:COG1196 655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 821 QMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRL------------RQQEQKQYqdsteiasgkkdgph 888
Cdd:COG1196 735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaieeyeELEERYDF--------------- 799
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1769843730 889 gsvLEEGLDDyltrLIEERDTLMrtgvynhedRIISELDRQIREIL 934
Cdd:COG1196 800 ---LSEQRED----LEEARETLE---------EAIEEIDRETRERF 829
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
594-755 |
3.96e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 3.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 594 SEIQTEPRETLEYKAALElEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQktliD 673
Cdd:TIGR02169 301 AEIASLERSIAEKERELE-DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE----E 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 674 LEKREQQLASVESELQREKKELQSER---QRNLQELQDSIRRA------------------------KEDCIHQVELERL 726
Cdd:TIGR02169 376 VDKEFAETRDELKDYREKLEKLKREInelKRELDRLQEELQRLseeladlnaaiagieakineleeeKEDKALEIKKQEW 455
|
170 180
....*....|....*....|....*....
gi 1769843730 727 KIKQLEEDKHRLQQQLNDAENKYKILEKE 755
Cdd:TIGR02169 456 KLEQLAADLSKYEQELYDLKEEYDRVEKE 484
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
598-871 |
4.19e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.40 E-value: 4.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 598 TEPRETLEYKAAlELEMWKEMQEDiFENQLKQKELAH-------------MQALAEEWKKRDRERESLVKKKvaeytile 664
Cdd:pfam01576 1 TRQEEEMQAKEE-ELQKVKERQQK-AESELKELEKKHqqlceeknalqeqLQAETELCAEAEEMRARLAARK-------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 665 GKLQKTLIDLEKREQQLASVESELQREKKELQSerqrNLQELQDSIRrAKEDCIHQVELERL----KIKQLEEDKHRLQQ 740
Cdd:pfam01576 71 QELEEILHELESRLEEEEERSQQLQNEKKKMQQ----HIQDLEEQLD-EEEAARQKLQLEKVtteaKIKKLEEDILLLED 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 741 QLNDAENKYKILEKEFQQFKDQQNNKPE--IRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQR-- 816
Cdd:pfam01576 146 QNSKLSKERKLLEERISEFTSNLAEEEEkaKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQia 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1769843730 817 EQESQMARLK----KQQEELE--QMRLRYLAAEEKDTVKTERQ---ELLDIRNELNRLRQQEQK 871
Cdd:pfam01576 226 ELQAQIAELRaqlaKKEEELQaaLARLEEETAQKNNALKKIREleaQISELQEDLESERAARNK 289
|
|
| MscS_porin |
pfam12795 |
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part ... |
646-878 |
4.48e-04 |
|
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part of the turgor-driven solute efflux system that protects bacteria from lysis in the event of osmotic shock. The MscS protein alone is sufficient to form a functional mechanosensitive channel gated directly by tension in the lipid bilayer. The MscS proteins are heptamers of three transmembrane subunits with seven converging M3 domains, and this MscS_porin is towards the N-terminal of the molecules. The high concentration of negative charges at the extracellular entrance of the pore helps select the cations for efflux.
Pssm-ID: 432790 [Multi-domain] Cd Length: 238 Bit Score: 43.06 E-value: 4.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 646 DRERESLVKKKVAEYtilegkLQKTLIDLEKRE---QQLASVESELQREKKELQsERQRNLQELQDSIRRAKedcihQVE 722
Cdd:pfam12795 7 KAKLDEAAKKKLLQD------LQQALSLLDKIDaskQRAAAYQKALDDAPAELR-ELRQELAALQAKAEAAP-----KEI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 723 LERLKIKQLEedkhrlqQQLNDAENKYKILEKEFQQFKDQ---QNNKPEiRLQSEINLLTLEKVELERKLESATKSKlhy 799
Cdd:pfam12795 75 LASLSLEELE-------QRLLQTSAQLQELQNQLAQLNSQlieLQTRPE-RAQQQLSEARQRLQQIRNRLNGPAPPG--- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 800 kQQWGRALKELARLKQREQESQMARLKKQQE------ELEQMRLRYLAAEekdtVKTERQELLDIRNELNRLRQQEQKQY 873
Cdd:pfam12795 144 -EPLSEAQRWALQAELAALKAQIDMLEQELLsnnnrqDLLKARRDLLTLR----IQRLEQQLQALQELLNEKRLQEAEQA 218
|
....*
gi 1769843730 874 QDSTE 878
Cdd:pfam12795 219 VAQTE 223
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
725-878 |
5.04e-04 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 42.20 E-value: 5.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 725 RLKIKQLEEDKHRLQQQLNDAENKYKIL-------EKEFQQFKDQQNNKPEI--RLQSEINLLTLEKVELERKLESATKS 795
Cdd:pfam15619 10 LHKIKELQNELAELQSKLEELRKENRLLkrlqkrqEKALGKYEGTESELPQLiaRHNEEVRVLRERLRRLQEKERDLERK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 796 KLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKdTVKTERQ-ELLDirNELNRLRQQEQKQYQ 874
Cdd:pfam15619 90 LKEKEAELLRLRDQLKRLEKLSEDKNLAEREELQKKLEQLEAKLEDKDEK-IQDLERKlELEN--KSFRRQLAAEKKKHK 166
|
....
gi 1769843730 875 DSTE 878
Cdd:pfam15619 167 EAQE 170
|
|
| DUF4659 |
pfam15558 |
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins ... |
629-885 |
6.37e-04 |
|
Domain of unknown function (DUF4659); This family of proteins is found in eukaryotes. Proteins in this family are typically between 427 and 674 amino acids in length. There are two completely conserved residues (D and I) that may be functionally important.
Pssm-ID: 464768 [Multi-domain] Cd Length: 374 Bit Score: 43.10 E-value: 6.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 629 QKELAHMQALAEEWKKRDRERESLvkkkvaEYTILEGKLQKTLIDLEKRE---QQLASVESELQREKKELQSERQRNLQE 705
Cdd:pfam15558 37 LRRRDQKRQETLERERRLLLQQSQ------EQWQAEKEQRKARLGREERRradRREKQVIEKESRWREQAEDQENQRQEK 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 706 LQDSIRRAKEDCIHQVelERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLeKVEL 785
Cdd:pfam15558 111 LERARQEAEQRKQCQE--QRLKEKEEELQALREQNSLQLQERLEEACHKRQLKEREEQKKVQENNLSELLNHQAR-KVLV 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 786 ERK-----------LE-SATKSKLHYKQQWGRALKEL-ARLKQREQESQMARLK-KQQEELEQMRLRYLAAEEK------ 845
Cdd:pfam15558 188 DCQakaeellrrlsLEqSLQRSQENYEQLVEERHRELrEKAQKEEEQFQRAKWRaEEKEEERQEHKEALAELADrkiqqa 267
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1769843730 846 -----DTVKTERQELLDIRNE------LNRLR-QQEQKQYQDSTEIASGKKD 885
Cdd:pfam15558 268 rqvahKTVQDKAQRARELNLEreknhhILKLKvEKEEKCHREGIKEAIKKKE 319
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
610-834 |
6.81e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 42.70 E-value: 6.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 610 LELEMW--KEMQEDI-----FENQLKQKELAHMQALAEEWKKRDRERESLVKKK---VAEYTILEGK---------LQKT 670
Cdd:smart00787 65 LELYQFscKELKKYIsegrdLFKEIEEETLINNPPLFKEYFSASPDVKLLMDKQfqlVKTFARLEAKkmwyewrmkLLEG 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 671 LIDlekreqQLASVESELQREKKELQSERQRnLQELQDSIRRAKEDCIHQVELERlkikQLEEDKHRLQQ-QLNDAENKY 749
Cdd:smart00787 145 LKE------GLDENLEGLKEDYKLLMKELEL-LNSIKPKLRDRKDALEEELRQLK----QLEDELEDCDPtELDRAKEKL 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 750 KILEKEFQQFKDQQNNkpeirlqseinlLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREqESQMARLKKQQ 829
Cdd:smart00787 214 KKLLQEIMIKVKKLEE------------LEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFT-FKEIEKLKEQL 280
|
....*
gi 1769843730 830 EELEQ 834
Cdd:smart00787 281 KLLQS 285
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
616-831 |
7.43e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.83 E-value: 7.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 616 KEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLasvESELQREKKEL 695
Cdd:COG4942 30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL---RAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 696 --------QSERQRNLQEL------QDSIRRAKEdcIHQVELERLK-IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFK 760
Cdd:COG4942 107 aellralyRLGRQPPLALLlspedfLDAVRRLQY--LKYLAPARREqAEELRADLAELAALRAELEAERAELEALLAELE 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1769843730 761 DQQNnkpeiRLQSEINlltlEKVELERKLESATKSKlhykqqwgraLKELARLKQREQ--ESQMARLKKQQEE 831
Cdd:COG4942 185 EERA-----ALEALKA----ERQKLLARLEKELAEL----------AAELAELQQEAEelEALIARLEAEAAA 238
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
598-930 |
9.00e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.29 E-value: 9.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 598 TEPRETLEYKAALE----LEMWKEMQEDIFENQLKQKELA--HMQALAEEW-------KKRDRERESLVKKKVAEYTIL- 663
Cdd:pfam12128 374 TAKYNRRRSKIKEQnnrdIAGIKDKLAKIREARDRQLAVAedDLQALESELreqleagKLEFNEEEYRLKSRLGELKLRl 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 664 -------EGKLQKTLIDL------EKREQQLASVESeLQREKKELQSERQRNLQELQDSIRRAKEdciHQVELERLKiKQ 730
Cdd:pfam12128 454 nqatatpELLLQLENFDErierarEEQEAANAEVER-LQSELRQARKRRDQASEALRQASRRLEE---RQSALDELE-LQ 528
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 731 LEEDKHRLQQQLND-----AENKYKILEKEFQQFKDQQnnkPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGR 805
Cdd:pfam12128 529 LFPQAGTLLHFLRKeapdwEQSIGKVISPELLHRTDLD---PEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRER 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 806 ALK-----ELARLKQREQESQMARLKKQQEEL---------------------------EQMRLRYLAAEEKDTVKTERQ 853
Cdd:pfam12128 606 LDKaeealQSAREKQAAAEEQLVQANGELEKAsreetfartalknarldlrrlfdekqsEKDKKNKALAERKDSANERLN 685
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1769843730 854 ElLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLmRTGVYNHEDRIISELDRQI 930
Cdd:pfam12128 686 S-LEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAAR-RSGAKAELKALETWYKRDL 760
|
|
| BRE1 |
pfam08647 |
BRE1 E3 ubiquitin ligase; BRE1 is an E3 ubiquitin ligase that has been shown to act as a ... |
629-746 |
1.35e-03 |
|
BRE1 E3 ubiquitin ligase; BRE1 is an E3 ubiquitin ligase that has been shown to act as a transcriptional activator through direct activator interactions.
Pssm-ID: 462547 [Multi-domain] Cd Length: 95 Bit Score: 38.72 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 629 QKELAHMQAlaeEWKKRDrereSLVKKKVAEYTILEGKLQKTLIDLEKREQQLAsvesELQREKKELQSERqRNLQelqd 708
Cdd:pfam08647 2 QTELVKLEQ---AFEELS----EQLDKKVKDLTILEEKKLRLEAEKAKADQKYF----AAMRSKDALENEN-KKLN---- 65
|
90 100 110
....*....|....*....|....*....|....*...
gi 1769843730 709 sirrakedciHQVELERLKIKQLEEDKHRLQQQLNDAE 746
Cdd:pfam08647 66 ----------TLLSKSSELIEQLKETEKEFVRKLKNLE 93
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
639-880 |
1.69e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.44 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 639 AEEWKKRDRERESLVKKKVAEYTILEGklqktlidlEKREQQLASVESELQREKKELQSERQRNLQElqdsIRRAKEDCI 718
Cdd:PTZ00121 1196 AEDARKAEAARKAEEERKAEEARKAED---------AKKAEAVKKAEEAKKDAEEAKKAEEERNNEE----IRKFEEARM 1262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 719 HQVELERLKIKQLEEDKhrlQQQLNDAENKYKilekefqqfKDQQNNKPEIRLQSEINlltlEKVELERKLESATKSKLH 798
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARK---ADELKKAEEKKK---------ADEAKKAEEKKKADEAK----KKAEEAKKADEAKKKAEE 1326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 799 YKQQwGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTE 878
Cdd:PTZ00121 1327 AKKK-ADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405
|
..
gi 1769843730 879 IA 880
Cdd:PTZ00121 1406 KA 1407
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
596-867 |
1.83e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.34 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 596 IQTEPRETLEYKAALE-LEMWKEMQEDIfENQLKQKElAHMQALAEEWKKRDRERESLVK--KKVAEYTILEGKLQKTLI 672
Cdd:TIGR00606 195 RQTQGQKVQEHQMELKyLKQYKEKACEI-RDQITSKE-AQLESSREIVKSYENELDPLKNrlKEIEHNLSKIMKLDNEIK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 673 DLEKREQQLASVESEL----------------------QREKKELQSERQRNLQELQDSIRRAKEDCIHQVELE-RLKIK 729
Cdd:TIGR00606 273 ALKSRKKQMEKDNSELelkmekvfqgtdeqlndlyhnhQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLvEQGRL 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 730 QLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRlqseiNLLTLEKVELERKLESATK------SKLHYKQQW 803
Cdd:TIGR00606 353 QLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIK-----NFHTLVIERQEDEAKTAAQlcadlqSKERLKQEQ 427
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 804 GRALKELARLKQREQESQMARLKKQQEELEQMR--LRYLAAEEKDTVKTErQELLDIRNELNRLRQ 867
Cdd:TIGR00606 428 ADEIRDEKKGLGRTIELKKEILEKKQEELKFVIkeLQQLEGSSDRILELD-QELRKAERELSKAEK 492
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
663-765 |
2.02e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.12 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 663 LEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQEL----QDSIRRAKE--DCIHQVELERLKIKQLEEDKH 736
Cdd:PRK00409 528 LERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAekeaQQAIKEAKKeaDEIIKELRQLQKGGYASVKAH 607
|
90 100
....*....|....*....|....*....
gi 1769843730 737 RLQQQLNDAENKYKILEKEFQQFKDQQNN 765
Cdd:PRK00409 608 ELIEARKRLNKANEKKEKKKKKQKEKQEE 636
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
682-813 |
2.11e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 682 ASVESELQREKKELQSERQRNLQELQDSIRRAKEDciHQVELERL--KIKQLEEDKHRLQQQLNDAENKYKILEKEFQQF 759
Cdd:COG2433 376 LSIEEALEELIEKELPEEEPEAEREKEHEERELTE--EEEEIRRLeeQVERLEAEVEELEAELEEKDERIERLERELSEA 453
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 760 KDQQNNkpEIRLQSEINLLTLEKVELERKLESA--TKSKLHYKQQwgrALKELARL 813
Cdd:COG2433 454 RSEERR--EIRKDREISRLDREIERLERELEEEreRIEELKRKLE---RLKELWKL 504
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
726-882 |
2.49e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 726 LKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDqqnnkpeirlqsEINLLTLEKVELERKLESATKSKLHYKQQWG- 804
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKT------------ELEDLEKEIKRLELEIEEVEARIKKYEEQLGn 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 805 -RALKELARLkQREQESQMARLKK-QQEELEQM----RLRYLAAEEKDTVKTERQELLDIRNELN----RLRQQEQKQYQ 874
Cdd:COG1579 85 vRNNKEYEAL-QKEIESLKRRISDlEDEILELMerieELEEELAELEAELAELEAELEEKKAELDeelaELEAELEELEA 163
|
....*...
gi 1769843730 875 DSTEIASG 882
Cdd:COG1579 164 EREELAAK 171
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
578-876 |
2.56e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.82 E-value: 2.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 578 SAVQQKPSSLPPAPCPSEIQTEPRETLEyKAALELEMWKEMQEDIfeNQLKQK------ELAHMQALAEEWKKRDRE--R 649
Cdd:PRK11281 39 ADVQAQLDALNKQKLLEAEDKLVQQDLE-QTLALLDKIDRQKEET--EQLKQQlaqapaKLRQAQAELEALKDDNDEetR 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 650 ESLVKKKVAEytiLEGKLQKTLIDLEKREQQLASVESEL--QREKKE-LQSERQRNLQELQdsirrakedcihqvELERL 726
Cdd:PRK11281 116 ETLSTLSLRQ---LESRLAQTLDQLQNAQNDLAEYNSQLvsLQTQPErAQAALYANSQRLQ--------------QIRNL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 727 KIKQLEEDK---HRLQQQLNdAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLEsatksklhykqqw 803
Cdd:PRK11281 179 LKGGKVGGKalrPSQRVLLQ-AEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQ------------- 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1769843730 804 grALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQ--KQYQDS 876
Cdd:PRK11281 245 --LLQEAINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLKATEKLNTLTQQNLrvKNWLDR 317
|
|
| GBP_C |
cd16269 |
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
615-778 |
2.58e-03 |
|
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.
Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 41.02 E-value: 2.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 615 WKEMQEDIFE--NQLKQKELAHMQALAEEWKKrdrereslvKKKVAEyTILEGKLQKTLIDLEKREQQLASVESELQREK 692
Cdd:cd16269 147 YLEDREKLVEkyRQVPRKGVKAEEVLQEFLQS---------KEAEAE-AILQADQALTEKEKEIEAERAKAEAAEQERKL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 693 KElqsERQRNL-QELQDSIRRakedciHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNkpeiRL 771
Cdd:cd16269 217 LE---EQQRELeQKLEDQERS------YEEHLRQLKEKMEEERENLLKEQERALESKLKEQEALLEEGFKEQAE----LL 283
|
....*..
gi 1769843730 772 QSEINLL 778
Cdd:cd16269 284 QEEIRSL 290
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
599-872 |
2.95e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 41.75 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 599 EPRETLEYKAAL------ELEMWKEMQEDIFENQLKQKELaHMQALAEEWK-KRDRERESL------VKKKVAEYTILEG 665
Cdd:pfam12128 251 NTLESAELRLSHlhfgykSDETLIASRQEERQETSAELNQ-LLRTLDDQWKeKRDELNGELsaadaaVAKDRSELEALED 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 666 KLQKTL-IDLEKREQ---QLASVESEL--QREKKELQSERQRNLQELQDSiRRAKEDCIHQVELERLKiKQLEEDKHRLQ 739
Cdd:pfam12128 330 QHGAFLdADIETAAAdqeQLPSWQSELenLEERLKALTGKHQDVTAKYNR-RRSKIKEQNNRDIAGIK-DKLAKIREARD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 740 QQLNDAENKYKILEKEFQQFKDQQNNkpEIRLQSEINLLTLEkvELERKLESATKSKlhykqqwgrALKElarlkqrEQE 819
Cdd:pfam12128 408 RQLAVAEDDLQALESELREQLEAGKL--EFNEEEYRLKSRLG--ELKLRLNQATATP---------ELLL-------QLE 467
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1769843730 820 SQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQ 872
Cdd:pfam12128 468 NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQS 520
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
623-941 |
3.15e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.25 E-value: 3.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 623 FENQLKQKE-LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVEselqrEKKELQSERQR 701
Cdd:pfam05483 211 LEMHFKLKEdHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLE-----EKTKLQDENLK 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 702 NLQELQDSIRRAKEDCIHQVELERLKIKQLEED---------------------------KHRL---------------- 738
Cdd:pfam05483 286 ELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDlqiatkticqlteekeaqmeelnkakaAHSFvvtefeattcsleell 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 739 ---QQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV-------------------------------- 783
Cdd:pfam05483 366 rteQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKIlaedeklldekkqfekiaeelkgkeqelifll 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 784 --------ELERKLESATKSKLHYKQQWGRALKEL--ARLKQREQESQMARLKKQQEELEQ----MRLRyLAAEEKDTVK 849
Cdd:pfam05483 446 qarekeihDLEIQLTAIKTSEEHYLKEVEDLKTELekEKLKNIELTAHCDKLLLENKELTQeasdMTLE-LKKHQEDIIN 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 850 TERQE-------------LLDIRNELNRLRqQEQKQYQDSTEIASGKKDGPHGSVLEEGL-DDYLTRLIEERDTLMRTGV 915
Cdd:pfam05483 525 CKKQEermlkqienleekEMNLRDELESVR-EEFIQKGDEVKCKLDKSEENARSIEYEVLkKEKQMKILENKCNNLKKQI 603
|
410 420
....*....|....*....|....*.
gi 1769843730 916 YNhEDRIISELDRQIREILAKSNASN 941
Cdd:pfam05483 604 EN-KNKNIEELHQENKALKKKGSAEN 628
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
607-896 |
3.17e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.57 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 607 KAALELEMWK------EMQEDIFEN-----QLKQKELAHMQalaEEWKKRDRERESLVKKKvAEYTILEGKLQ------- 668
Cdd:TIGR00606 285 NSELELKMEKvfqgtdEQLNDLYHNhqrtvREKERELVDCQ---RELEKLNKERRLLNQEK-TELLVEQGRLQlqadrhq 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 669 --KTLIDLEKREQQLasvESELQREKKELQSERQ-RNLQEL-----QDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQ 740
Cdd:TIGR00606 361 ehIRARDSLIQSLAT---RLELDGFERGPFSERQiKNFHTLvierqEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKG 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 741 QLNDAENKYKILEKEFQQFKDqqnnkpeirlqseinlltleKVELERKLESATKSKLHYKQQWGRALKELARL-KQREQE 819
Cdd:TIGR00606 438 LGRTIELKKEILEKKQEELKF--------------------VIKELQQLEGSSDRILELDQELRKAERELSKAeKNSLTE 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 820 SQMARLKK-QQEELEQMR-LRYLAAE--EKDTVKTERQELLDI-RNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEE 894
Cdd:TIGR00606 498 TLKKEVKSlQNEKADLDRkLRKLDQEmeQLNHHTTTRTQMEMLtKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED 577
|
..
gi 1769843730 895 GL 896
Cdd:TIGR00606 578 WL 579
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
628-853 |
3.20e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.29 E-value: 3.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 628 KQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQseRQRNLQELQ 707
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIA 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 708 DSIRRAKEDCIHQVeleRLKIKQLEEdKHRLQQQLNDAENKykiLEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELER 787
Cdd:COG4717 374 ALLAEAGVEDEEEL---RAALEQAEE-YQELKEELEELEEQ---LEELLGELEELLEALDEEELEEELEELEEELEELEE 446
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1769843730 788 KLESATKSKLHYKQQWgRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAA---EEKDTVKTERQ 853
Cdd:COG4717 447 ELEELREELAELEAEL-EQLEEDGELAELLQELEELKAELRELAEEWAALKLALElleEAREEYREERL 514
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
666-861 |
3.46e-03 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 41.04 E-value: 3.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 666 KLQKTL-IDLEKREQQLASVESELQREKKELQ------SERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHR- 737
Cdd:pfam15964 371 RLEKELaSQQEKRAQEKEALRKEMKKEREELGatmlalSQNVAQLEAQVEKVTREKNSLVSQLEEAQKQLASQEMDVTKv 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 738 ---LQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQsEINLLTLEKVELERKLESAtksklhyKQQWGRALKELAR-- 812
Cdd:pfam15964 451 cgeMRYQLNQTKMKKDEAEKEHREYRTKTGRQLEIKDQ-EIEKLGLELSESKQRLEQA-------QQDAARAREECLKlt 522
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1769843730 813 --LKQREQESQMARLKK---QQEELEQMRLRYLAAEEKDTVKTERQELLDIRNE 861
Cdd:pfam15964 523 elLGESEHQLHLTRLEKesiQQSFSNEAKAQALQAQQREQELTQKMQQMEAQHD 576
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
594-868 |
3.87e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 40.88 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 594 SEIQTEPRETLEYKAALEL--EMWKEMQEDIFENQLKQKELA-HMQALAE-EWKKRDRERESLVKKKVAEYTILEGKLQK 669
Cdd:pfam05557 125 LELQSTNSELEELQERLDLlkAKASEAEQLRQNLEKQQSSLAeAEQRIKElEFEIQSQEQDSEIVKNSKSELARIPELEK 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 670 TLIDLEKR--------------EQQLASVESELQREKK------ELQSERQRNLQELQDSIRRAKEDCIHQV--ELERLK 727
Cdd:pfam05557 205 ELERLREHnkhlnenienklllKEEVEDLKRKLEREEKyreeaaTLELEKEKLEQELQSWVKLAQDTGLNLRspEDLSRR 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 728 IKQLEEDKHRLQQQLNDAENKYKILEK---EFQQFKDQQNNKPE-------------IRLQSEINLLTLEKVELERKLES 791
Cdd:pfam05557 285 IEQLQQREIVLKEENSSLTSSARQLEKarrELEQELAQYLKKIEdlnkklkrhkalvRRLQRRVLLLTKERDGYRAILES 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 792 ATK--SKLHYKQQWGRALKELARLKQREQ---ESQMARLKKQQEELEQMRLRYLAAE-----------------EKDTVK 849
Cdd:pfam05557 365 YDKelTMSNYSPQLLERIEEAEDMTQKMQahnEEMEAQLSVAEEELGGYKQQAQTLErelqalrqqesladpsySKEEVD 444
|
330
....*....|....*....
gi 1769843730 850 TERQELLDIRNELNRLRQQ 868
Cdd:pfam05557 445 SLRRKLETLELERQRLREQ 463
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
601-797 |
4.40e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.52 E-value: 4.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 601 RETLEYKAALELEMWKEMQEDIFENQLKQKELAhmQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLI------DL 674
Cdd:COG4942 57 LAALERRIAALARRIRALEQELAALEAELAELE--KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLspedflDA 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 675 EKREQQLASVESELQREKKELQSERQRnLQELQDSIRRAKEdcihqvELERLKiKQLEEDKHRLQQQLNDAENKYKILEK 754
Cdd:COG4942 135 VRRLQYLKYLAPARREQAEELRADLAE-LAALRAELEAERA------ELEALL-AELEEERAALEALKAERQKLLARLEK 206
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1769843730 755 EFQQFKDQ--QNNKPEIRLQSEINLLTLEKVELERKLESATKSKL 797
Cdd:COG4942 207 ELAELAAElaELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
640-745 |
4.47e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.50 E-value: 4.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 640 EEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLAsvesELQREKKELQSERQRnLQELQDSIRRAKEDciH 719
Cdd:pfam13851 36 AELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLE----NYEKDKQSLKNLKAR-LKVLEKELKDLKWE--H 108
|
90 100
....*....|....*....|....*.
gi 1769843730 720 QVELERLkiKQLEEDKHRLQQQLNDA 745
Cdd:pfam13851 109 EVLEQRF--EKVERERDELYDKFEAA 132
|
|
| COG5644 |
COG5644 |
U3 small nucleolar RNA-associated protein 14 [Function unknown]; |
583-898 |
4.55e-03 |
|
U3 small nucleolar RNA-associated protein 14 [Function unknown];
Pssm-ID: 227931 [Multi-domain] Cd Length: 869 Bit Score: 40.84 E-value: 4.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 583 KPSSLPPAPCPSEIQTEPRETLEYKaaleleMWKEMQEDIFENQ---LKQKELAHMQALAEEWKKRDRE---------RE 650
Cdd:COG5644 315 ETARPVPSNNGLASSFEPRTESERK------MHQALLDAGLENEsalKKQEELALNKLSVEEVAERTRQlrfmrelmfRE 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 651 SLVKKKVAEytILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEdcihqvELERLkiKQ 730
Cdd:COG5644 389 ERKAKRVAK--IKSKTYRKIRKNRKEKEMALIPKSEDLENEKSEEARALERMTQRHKNTSSWTRK------MLERA--SH 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 731 LEEDKHRLQQQLNDAEN-KYKILEKEFQQFKDqqnnkpeIRLQSEINLLTLEKVELERKlesATKSKLHYKQQWGRALKE 809
Cdd:COG5644 459 GEGTREAVNEQIRKGDElMQRIHGKEIMDGED-------VSEFSDSDYDTNEQVSTAFE---KIRNEEELKGVLGMKFMR 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 810 LARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTV--KTERQELLDIRNELNRL--RQQEQKQYQDST-------E 878
Cdd:COG5644 529 DASNRQMAASKISVADLVKVENGDDIDVGELDEVGGDAIyaNAGRREVFPVVEQRRKLapRKRKEDFVTPSTsleksmdR 608
|
330 340
....*....|....*....|
gi 1769843730 879 IASGKKDGPHGSVLEEGLDD 898
Cdd:COG5644 609 ILHGQKKRAEGAVVFEKPLE 628
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
635-787 |
4.62e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 40.18 E-value: 4.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 635 MQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNlQELQDSIRRAk 714
Cdd:pfam15905 154 MSSLSMELMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSET-EKLLEYITEL- 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 715 EDCIHQVELERLKIKQLEED------------------KHRLQQQLNDAENKYKILEKEFQQfKDQQNNKPEIRLQSEIN 776
Cdd:pfam15905 232 SCVSEQVEKYKLDIAQLEELlkekndeieslkqsleekEQELSKQIKDLNEKCKLLESEKEE-LLREYEEKEQTLNAELE 310
|
170
....*....|.
gi 1769843730 777 LLTlEKVELER 787
Cdd:pfam15905 311 ELK-EKLTLEE 320
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
616-888 |
4.70e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 40.83 E-value: 4.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 616 KEMQEDIFENQLKQKELAHMQALAEEWK-KRDRERESLVKKKVAEYtilegKLQKTLIDLEKreqqlasveSELQREKKE 694
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREKKLRETEEvEFSLKAEVLIQKFGRSL-----KAKKRFSLLKK---------ETIYLQSAQ 875
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 695 LQSERQRNLQELQDSIRRAKEDCIHQVELERLKI---KQLEEDkhrLQQQLNDAENKYKILEK-------EFQQFKDQQN 764
Cdd:COG5022 876 RVELAERQLQELKIDVKSISSLKLVNLELESEIIelkKSLSSD---LIENLEFKTELIARLKKllnnidlEEGPSIEYVK 952
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 765 NKPEIRLQSEINLLTLEKVELERKLESATKSKLHYK------QQWGRALKELARLKQREQESqmarlKKQQEELEQMRLR 838
Cdd:COG5022 953 LPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNkanselKNFKKELAELSKQYGALQES-----TKQLKELPVEVAE 1027
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1769843730 839 YLAAEEKD-TVKTERQELLDIRnELNRLRQQEQKQYQDSTEIASGKKDGPH 888
Cdd:COG5022 1028 LQSASKIIsSESTELSILKPLQ-KLKGLLLLENNQLQARYKALKLRRENSL 1077
|
|
| HlpA |
COG2825 |
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ... |
635-721 |
5.13e-03 |
|
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 38.66 E-value: 5.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 635 MQALAEEWKKRDRERESLVKKKVAEYTILEGKLQK-----TLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDS 709
Cdd:COG2825 41 GKAAQKKLEKEFKKRQAELQKLEKELQALQEKLQKeaatlSEEERQKKERELQKKQQELQRKQQEAQQDLQKRQQELLQP 120
|
90
....*....|..
gi 1769843730 710 IRRAKEDCIHQV 721
Cdd:COG2825 121 ILEKIQKAIKEV 132
|
|
| F-BAR_PACSIN |
cd07655 |
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein ... |
694-872 |
5.22e-03 |
|
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons (PACSIN) proteins; F-BAR domains are dimerization modules that bind and bend membranes and are found in proteins involved in membrane dynamics and actin reorganization. Protein kinase C and Casein kinase Substrate in Neurons (PACSIN) proteins, also called Synaptic dynamin-associated proteins (Syndapins), act as regulators of cytoskeletal and membrane dynamics. They bind both dynamin and Wiskott-Aldrich syndrome protein (WASP), and may provide direct links between the actin cytoskeletal machinery through WASP and dynamin-dependent endocytosis. Vetebrates harbor three isoforms with distinct expression patterns and specific functions. PACSINs contain an N-terminal F-BAR domain and a C-terminal SH3 domain. F-BAR domains form banana-shaped dimers with a positively-charged concave surface that binds to negatively-charged lipid membranes. They can induce membrane deformation in the form of long tubules.
Pssm-ID: 153339 [Multi-domain] Cd Length: 258 Bit Score: 39.60 E-value: 5.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 694 ELQSERQRNLQ-ELQDSIRRAKEDCIHQVELERLK-IKQLEEDKHRLQQQ-------LNDAENKYKILEKEFQQFKDQQN 764
Cdd:cd07655 78 ELHLSIRDKLLnDVVEEVKTWQKENYHKSMMGGFKeTKEAEDGFAKAQKPwakllkkVEKAKKAYHAACKAEKSAQKQEN 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 765 NKpeirlQSEINLLTlEKV-ELERKLESATKSKLHYKQQWGRALKELARLKQREQESqMARLKKQQEELEQMRLRYLaae 843
Cdd:cd07655 158 NA-----KSDTSLSP-DQVkKLQDKVEKCKQEVSKTKDKYEKALEDLNKYNPRYMED-MEQVFDKCQEFEEKRLDFF--- 227
|
170 180
....*....|....*....|....*....
gi 1769843730 844 ekdtvkteRQELLDIRNELNRLRQQEQKQ 872
Cdd:cd07655 228 --------KEILLSYHRHLDLSTNPSFKA 248
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
594-874 |
5.53e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.26 E-value: 5.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 594 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEwKKRDRERESLVKKKVAEYTILEGKLQKtlid 673
Cdd:pfam07888 80 SRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAH-EARIRELEEDIKTLTQRVLERETELER---- 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 674 LEKREQQLASVESELQREKKELQS------------------------ERQRNLQELQDSIRR--AKEDCIHQVELErlk 727
Cdd:pfam07888 155 MKERAKKAGAQRKEEEAERKQLQAklqqteeelrslskefqelrnslaQRDTQVLQLQDTITTltQKLTTAHRKEAE--- 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 728 IKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNnkpeiRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGR-- 805
Cdd:pfam07888 232 NEALLEELRSLQERLNASERKVEGLGEELSSMAAQRD-----RTQAELHQARLQAAQLTLQLADASLALREGRARWAQer 306
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1769843730 806 ------ALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDT----VKTERQELLDIRNELnRLRQQEQKQYQ 874
Cdd:pfam07888 307 etlqqsAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREKDCnrvqLSESRRELQELKASL-RVAQKEKEQLQ 384
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
601-932 |
5.75e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.41 E-value: 5.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 601 RETLEyKAALELEMWKEMQEDIFEnqLKQkELAHMQALAEEwkkRDRERESLvKKKVAEytilegkLQKTLIDLEKREQQ 680
Cdd:PRK02224 233 RETRD-EADEVLEEHEERREELET--LEA-EIEDLRETIAE---TEREREEL-AEEVRD-------LRERLEELEEERDD 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 681 LASvESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFqqfk 760
Cdd:PRK02224 298 LLA-EAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESEL---- 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 761 dqQNNKPEIRLQSEinlltlEKVELERKLESATKSKLHYKQQWGRA-------LKELARLKQREQESQmARLKKQQEELE 833
Cdd:PRK02224 373 --EEAREAVEDRRE------EIEELEEEIEELRERFGDAPVDLGNAedfleelREERDELREREAELE-ATLRTARERVE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 834 QMRlRYLAA-------------EEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDyL 900
Cdd:PRK02224 444 EAE-ALLEAgkcpecgqpvegsPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERRED-L 521
|
330 340 350
....*....|....*....|....*....|..
gi 1769843730 901 TRLIEERdtlmRTGVYNHEDRiISELDRQIRE 932
Cdd:PRK02224 522 EELIAER----RETIEEKRER-AEELRERAAE 548
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
666-872 |
6.00e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 40.39 E-value: 6.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 666 KLQKTLIDLEKREQQLASVESELQREKKELQsERQRNLQELQDSIRRaKEDCIHQV--ELERLK--------------IK 729
Cdd:TIGR04523 240 EINEKTTEISNTQTQLNQLKDEQNKIKKQLS-EKQKELEQNNKKIKE-LEKQLNQLksEISDLNnqkeqdwnkelkseLK 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 730 QLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNK--PEIRLQSEINlltlEKVELERKLESATKSKLHYKQQWGRAL 807
Cdd:TIGR04523 318 NQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSesENSEKQRELE----EKQNEIEKLKKENQSYKQEIKNLESQI 393
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1769843730 808 KELAR-LKQREQESQM--ARLKKQQEEL-----EQMRLRYLAAEEKDTVK--TERQELLDIR-NELNRLRQQEQKQ 872
Cdd:TIGR04523 394 NDLESkIQNQEKLNQQkdEQIKKLQQEKellekEIERLKETIIKNNSEIKdlTNQDSVKELIiKNLDNTRESLETQ 469
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
632-937 |
6.11e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.71 E-value: 6.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 632 LAHMQALAEEWKKRDRERESLV--KKKVAEYTILEGKLQktlIDLEKREQQLASV-ESELQREK----------KELQSE 698
Cdd:PRK04863 289 LELRRELYTSRRQLAAEQYRLVemARELAELNEAESDLE---QDYQAASDHLNLVqTALRQQEKieryqadleeLEERLE 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 699 RQRNLQELQDSirrakedcihQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLL 778
Cdd:PRK04863 366 EQNEVVEEADE----------QQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLCGLPDL 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 779 TLEKV-----ELERKLESATKSKLHYKQ----------QWGRALKELARL-----------KQREQESQMARLKKQQEEL 832
Cdd:PRK04863 436 TADNAedwleEFQAKEQEATEELLSLEQklsvaqaahsQFEQAYQLVRKIagevsrseawdVARELLRRLREQRHLAEQL 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 833 EQMRLRyLAAEEKDTVKTERQELLdirneLNRLRQQEQKQYQDSTEIASGKKDgpHGSVLEEgLDDYLTRLIEERDTLmr 912
Cdd:PRK04863 516 QQLRMR-LSELEQRLRQQQRAERL-----LAEFCKRLGKNLDDEDELEQLQEE--LEARLES-LSESVSEARERRMAL-- 584
|
330 340
....*....|....*....|....*
gi 1769843730 913 tgvynheDRIISELDRQIREILAKS 937
Cdd:PRK04863 585 -------RQQLEQLQARIQRLAARA 602
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
654-868 |
6.28e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.14 E-value: 6.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 654 KKKVAEYTILEGKLQKTLIDLEKREQQ----LASVESELQREKKELQSERQRNLQELQDSIRRAKEdcihqveleRLKIK 729
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEellaALGLPPDLSPEELLELLDRIEELQELLREAEELEE---------ELQLE 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 730 QLEEDKHRLQQQLN-DAENKYKILEKEFQQFKDQQNNKPEIRLQseinlLTLEKVELERKLESATKSKLhyKQQWGRALK 808
Cdd:COG4717 367 ELEQEIAALLAEAGvEDEEELRAALEQAEEYQELKEELEELEEQ-----LEELLGELEELLEALDEEEL--EEELEELEE 439
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 809 ELARLkQREQESQMARLKKQQEELEQMrlrylaaEEKDTVKTERQELLDIRNELNRLRQQ 868
Cdd:COG4717 440 ELEEL-EEELEELREELAELEAELEQL-------EEDGELAELLQELEELKAELRELAEE 491
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
656-940 |
6.60e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.33 E-value: 6.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 656 KVAEYTILEGKLQKTLIDLEKREQQLASVE--SELQREKKELQSERQRNLQELQDSIR---------------------- 711
Cdd:PRK04863 339 LVQTALRQQEKIERYQADLEELEERLEEQNevVEEADEQQEENEARAEAAEEEVDELKsqladyqqaldvqqtraiqyqq 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 712 ------RAKEDC------IHQVE--LERLKIKQLEEDKHRLQ--QQLNDAENKYKILEKEFQQFKdqqnnkpeiRLQSEI 775
Cdd:PRK04863 419 avqaleRAKQLCglpdltADNAEdwLEEFQAKEQEATEELLSleQKLSVAQAAHSQFEQAYQLVR---------KIAGEV 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 776 NLLTLEKV--ELERKLESAtKSKLHYKQQWGRALKELAR--LKQREQESQMARLKKQ--------------QEELEQMR- 836
Cdd:PRK04863 490 SRSEAWDVarELLRRLREQ-RHLAEQLQQLRMRLSELEQrlRQQQRAERLLAEFCKRlgknlddedeleqlQEELEARLe 568
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 837 -LRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQK--QYQDSTEiasgkKDGPH-GSVLE--EGLDDYLTRLIE-ERDT 909
Cdd:PRK04863 569 sLSESVSEARERRMALRQQLEQLQARIQRLAARAPAwlAAQDALA-----RLREQsGEEFEdsQDVTEYMQQLLErEREL 643
|
330 340 350
....*....|....*....|....*....|....
gi 1769843730 910 LMrtgvynHEDRI---ISELDRQIREILAKSNAS 940
Cdd:PRK04863 644 TV------ERDELaarKQALDEEIERLSQPGGSE 671
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
687-868 |
6.87e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 39.51 E-value: 6.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 687 ELQREKKELQSERQRNLQELQDSIRRAKEdcihqvelERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNk 766
Cdd:COG1340 12 ELEEKIEELREEIEELKEKRDELNEELKE--------LAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDE- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 767 peirLQSEINLLTLEKVELERKLESATKSKLHYKQqwgrALKELARLKQREQES------------QMARLKKQQEELEQ 834
Cdd:COG1340 83 ----LNEKLNELREELDELRKELAELNKAGGSIDK----LRKEIERLEWRQQTEvlspeeekelveKIKELEKELEKAKK 154
|
170 180 190
....*....|....*....|....*....|....
gi 1769843730 835 MRlrylaaEEKDTVKTERQELLDIRNELNRLRQQ 868
Cdd:COG1340 155 AL------EKNEKLKELRAELKELRKEAEEIHKK 182
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
633-891 |
8.38e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 39.43 E-value: 8.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 633 AHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESE---LQREKKELQSERQRNLQELQDS 709
Cdd:COG3883 12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEidkLQAEIAEAEAEIEERREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 710 IRRAKEDCIHQVELERL--------------KIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQqnnkpeirLQSEI 775
Cdd:COG3883 92 ARALYRSGGSVSYLDVLlgsesfsdfldrlsALSKIADADADLLEELKADKAELEAKKAELEAKLAE--------LEALK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 776 NLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQEL 855
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 243
|
250 260 270
....*....|....*....|....*....|....*.
gi 1769843730 856 LDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSV 891
Cdd:COG3883 244 ASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAA 279
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
657-868 |
8.74e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 39.88 E-value: 8.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 657 VAEYTILEGKLQKTLIDLEKREQQLA---SVESELQREKKELQSERQ-------------RNLQELQDSIRRAKEDC--- 717
Cdd:PRK01156 182 ISNIDYLEEKLKSSNLELENIKKQIAddeKSHSITLKEIERLSIEYNnamddynnlksalNELSSLEDMKNRYESEIkta 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 718 ---IHQVELERLKIKQLEEdkhRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEI--RLQSEINlltlEKVELERKLESA 792
Cdd:PRK01156 262 esdLSMELEKNNYYKELEE---RHMKIINDPVYKNRNYINDYFKYKNDIENKKQIlsNIDAEIN----KYHAIIKKLSVL 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1769843730 793 TKSKLHY---KQQWGRALKELARLKQREQESQMA-------RLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNEL 862
Cdd:PRK01156 335 QKDYNDYikkKSRYDDLNNQILELEGYEMDYNSYlksieslKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEI 414
|
....*.
gi 1769843730 863 NRLRQQ 868
Cdd:PRK01156 415 NVKLQD 420
|
|
| |
