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Conserved domains on  [gi|1063734601|ref|NP_001332421|]
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high chlorophyll fluorescent 109 [Arabidopsis thaliana]

Protein Classification

PCRF domain-containing protein( domain architecture ID 1750053)

peptide chain release factor (PCRF) domain-containing protein similar to Homo sapiens mitochondrial peptide chain release factor 1 (MTRF1), MTRF1-like and 28S mitochondrial ribosomal protein S35 (MRPS35)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PCRF super family cl40670
This domain is found in peptide chain release factors;
79-356 4.38e-98

This domain is found in peptide chain release factors;


The actual alignment was detected with superfamily member TIGR00020:

Pssm-ID: 477417 [Multi-domain]  Cd Length: 364  Bit Score: 296.30  E-value: 4.38e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601  79 DFYTLRKDVEIASARVEEIRASANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAET 158
Cdd:TIGR00020   1 EINEVNNRIEDLTSRLDTVRGSLDPEKKKARLEELEKEMEDPNFWNDQERAQAVIKERSSLEAVLDTLEELKNSLEDLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 159 IVKLTEEMDSTDVSLLEEAMgiIKELNKSLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQR 238
Cdd:TIGR00020  81 LLELAVEEDDEETFNELDAE--LKALEKKLAELELRTMLSGEYDANNAYLTIQAGAGGTEAQDWASMLYRMYLRWAERRG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 239 YKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEEaVGIEIPEEDL 318
Cdd:TIGR00020 159 FKVEIIDYSEGEEAGIKSVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHTSFASVFVMPEVDDD-IDIEIKPEDL 237

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1063734601 319 DISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRC-TDR 356
Cdd:TIGR00020 238 RIDTYRASGAGGQHVNKTDSAVRITHIPTGIVVQCqNDR 276
 
Name Accession Description Interval E-value
prfB TIGR00020
peptide chain release factor 2; In many but not all taxa, there is a conserved real ...
 79-356 4.38e-98

peptide chain release factor 2; In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a Pfam model called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. [Protein synthesis, Translation factors]


Pssm-ID: 272858 [Multi-domain]  Cd Length: 364  Bit Score: 296.30  E-value: 4.38e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601  79 DFYTLRKDVEIASARVEEIRASANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAET 158
Cdd:TIGR00020   1 EINEVNNRIEDLTSRLDTVRGSLDPEKKKARLEELEKEMEDPNFWNDQERAQAVIKERSSLEAVLDTLEELKNSLEDLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 159 IVKLTEEMDSTDVSLLEEAMgiIKELNKSLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQR 238
Cdd:TIGR00020  81 LLELAVEEDDEETFNELDAE--LKALEKKLAELELRTMLSGEYDANNAYLTIQAGAGGTEAQDWASMLYRMYLRWAERRG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 239 YKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEEaVGIEIPEEDL 318
Cdd:TIGR00020 159 FKVEIIDYSEGEEAGIKSVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHTSFASVFVMPEVDDD-IDIEIKPEDL 237

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1063734601 319 DISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRC-TDR 356
Cdd:TIGR00020 238 RIDTYRASGAGGQHVNKTDSAVRITHIPTGIVVQCqNDR 276
PRK05589 PRK05589
peptide chain release factor 2; Provisional
 122-353 3.06e-84

peptide chain release factor 2; Provisional


Pssm-ID: 235520 [Multi-domain]  Cd Length: 325  Bit Score: 259.35  E-value: 3.06e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 122 FWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDStdvSLLEEAMGIIKELNKSLDKFELTQLLSGPY 201
Cdd:PRK05589    6 FWNDIKEAQEITSEEKYLKDKLDKYNHLRNRIEDIEVLCEMMSEEDD---EMKKEIISEVKNIKEEIDRFKIETLLSGEY 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 202 DKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVR 281
Cdd:PRK05589   83 DRNNAILTLHSGVGGTDAQDWTEMLLRMYTRWAEKKGYKVEIIDLLEGDEAGIKSVTLKITGEFAYGYLKAEKGIHRLVR 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063734601 282 QSPFNSKGLRQTSFSGVEVMPLLPEEAvGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRC 353
Cdd:PRK05589  163 ISPFNANGKRQTSFASVEVLPELTDDQ-DIEIRSEDLKIDTYRAGGAGGQHVNKTESAVRITHIPTGIVVQC 233
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 106-298 4.33e-64

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 203.00  E-value: 4.33e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 106 LEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDstdvsLLEEAMGIIKELN 185
Cdd:pfam03462   1 LEERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEAYREYKQALEDLEEAKELLEDPE-----LAELAEEELEELE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 186 KSLDKF--ELTQLLS--GPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEI 261
Cdd:pfam03462  76 KRLEELeeELKLLLLpkDPNDDKNAILEIRAGAGGDEAALFAGDLFRMYTRYAERKGWKVEVLDYSETEAGGIKEATFEI 155

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063734601 262 EGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGV 298
Cdd:pfam03462 156 SGEGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 103-365 1.48e-44

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 157.47  E-value: 1.48e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 103 LQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETivklTEEM--DSTDVSLLEEAMGI 180
Cdd:COG0216     6 LEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEE----AKELleEESDPEMREMAKEE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 181 IKELNKSLDKFE--LTQLL--SGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKS 256
Cdd:COG0216    82 LEELEARLEELEeeLKILLlpKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGYKE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 257 ATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPllpE-EAVGIEIPEEDLDISFTRAGGKGGQNVNK 335
Cdd:COG0216   162 VIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLP---EaEEVDVEINPKDLRIDTFRSSGAGGQHVNT 238

                         250       260       270
                  ....*....|....*....|....*....|
gi 1063734601 336 VETAVRITHIPTGVAVRCTDrvgccrgEKS 365
Cdd:COG0216   239 TDSAVRITHLPTGIVVECQD-------ERS 261
PCRF smart00937
This domain is found in peptide chain release factors;
161-273 4.34e-39

This domain is found in peptide chain release factors;


Pssm-ID: 214923 [Multi-domain]  Cd Length: 116  Bit Score: 135.67  E-value: 4.34e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601  161 KLTEEMDstDVSLLEEAMGIIKELN----KSLDKFELTQLLSG-PYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGE 235
Cdd:smart00937   1 ELLEEEE--DDEMRELAEEELEELEaeleEELEELLKLLLLPKdPNDDKNAILEIRAGAGGDEAALFAGDLLRMYLRYAE 78

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1063734601  236 KQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGE 273
Cdd:smart00937  79 RKGWKVEVLDESEGELGGIKEATLKISGEGAYGKLKFE 116
 
Name Accession Description Interval E-value
prfB TIGR00020
peptide chain release factor 2; In many but not all taxa, there is a conserved real ...
 79-356 4.38e-98

peptide chain release factor 2; In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a Pfam model called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. [Protein synthesis, Translation factors]


Pssm-ID: 272858 [Multi-domain]  Cd Length: 364  Bit Score: 296.30  E-value: 4.38e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601  79 DFYTLRKDVEIASARVEEIRASANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAET 158
Cdd:TIGR00020   1 EINEVNNRIEDLTSRLDTVRGSLDPEKKKARLEELEKEMEDPNFWNDQERAQAVIKERSSLEAVLDTLEELKNSLEDLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 159 IVKLTEEMDSTDVSLLEEAMgiIKELNKSLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQR 238
Cdd:TIGR00020  81 LLELAVEEDDEETFNELDAE--LKALEKKLAELELRTMLSGEYDANNAYLTIQAGAGGTEAQDWASMLYRMYLRWAERRG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 239 YKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEEaVGIEIPEEDL 318
Cdd:TIGR00020 159 FKVEIIDYSEGEEAGIKSVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHTSFASVFVMPEVDDD-IDIEIKPEDL 237

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1063734601 319 DISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRC-TDR 356
Cdd:TIGR00020 238 RIDTYRASGAGGQHVNKTDSAVRITHIPTGIVVQCqNDR 276
PRK05589 PRK05589
peptide chain release factor 2; Provisional
 122-353 3.06e-84

peptide chain release factor 2; Provisional


Pssm-ID: 235520 [Multi-domain]  Cd Length: 325  Bit Score: 259.35  E-value: 3.06e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 122 FWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDStdvSLLEEAMGIIKELNKSLDKFELTQLLSGPY 201
Cdd:PRK05589    6 FWNDIKEAQEITSEEKYLKDKLDKYNHLRNRIEDIEVLCEMMSEEDD---EMKKEIISEVKNIKEEIDRFKIETLLSGEY 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 202 DKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVR 281
Cdd:PRK05589   83 DRNNAILTLHSGVGGTDAQDWTEMLLRMYTRWAEKKGYKVEIIDLLEGDEAGIKSVTLKITGEFAYGYLKAEKGIHRLVR 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063734601 282 QSPFNSKGLRQTSFSGVEVMPLLPEEAvGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRC 353
Cdd:PRK05589  163 ISPFNANGKRQTSFASVEVLPELTDDQ-DIEIRSEDLKIDTYRAGGAGGQHVNKTESAVRITHIPTGIVVQC 233
PRK07342 PRK07342
peptide chain release factor 2; Provisional
 116-353 1.35e-72

peptide chain release factor 2; Provisional


Pssm-ID: 235997 [Multi-domain]  Cd Length: 339  Bit Score: 230.15  E-value: 1.35e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 116 KATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEmdSTDVSLLEEAMGIIKELNKSLDKFELTQ 195
Cdd:PRK07342    2 KAEDPSLWNDAQEAQKLMRERQQLDDSINGINHLEQTLNDNIELIAMGEE--EGDKSIVEDAEKTIRDLKDEIDRRQIDA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 196 LLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKG 275
Cdd:PRK07342   80 LLSGEADANDTYLEVHAGAGGTESQDWASMLLRMYTRWAERQGRKVEVLEVHDGEEAGIKSATILVKGHNAYGWLKTESG 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063734601 276 THRIVRQSPFNSKGLRQTSFSGVEVMPLLpEEAVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRC 353
Cdd:PRK07342  160 VHRLVRISPYDSNARRHTSFASIWVYPVI-DDNIEVDVNESDVRIDTYRSSGAGGQHVNTTDSAVRITHIPTGIVVQC 236
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 106-298 4.33e-64

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 203.00  E-value: 4.33e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 106 LEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDstdvsLLEEAMGIIKELN 185
Cdd:pfam03462   1 LEERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEAYREYKQALEDLEEAKELLEDPE-----LAELAEEELEELE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 186 KSLDKF--ELTQLLS--GPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEI 261
Cdd:pfam03462  76 KRLEELeeELKLLLLpkDPNDDKNAILEIRAGAGGDEAALFAGDLFRMYTRYAERKGWKVEVLDYSETEAGGIKEATFEI 155

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063734601 262 EGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGV 298
Cdd:pfam03462 156 SGEGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
PRK08787 PRK08787
peptide chain release factor 2; Provisional
 150-353 2.60e-63

peptide chain release factor 2; Provisional


Pssm-ID: 136970 [Multi-domain]  Cd Length: 313  Bit Score: 205.28  E-value: 2.60e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 150 KTMVEDAETIVKLTEEMDSTDVSLLEE----AMGIIKELNK---SLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDW 222
Cdd:PRK08787    4 KTVIGIADVLSGLADAGELLDLAESEQdedtALAVIADLDKyqaHVEKLEFQRMFSGQMDGANAFVDIQAGAGGTEAQDW 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 223 ADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMP 302
Cdd:PRK08787   84 AEILLRMYLRWAESRGWKTELMEVSGGEVAGIKSATVRIEGEYAYGWLKTEIGVHRLVRKSPFDSDNRRHTSFTSVFVSP 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1063734601 303 LLpEEAVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRC 353
Cdd:PRK08787  164 EV-DDNIEIDINPADLRTDVYRSSGAGGQHVNKTESAVRITHIPTNTVVAC 213
PRK06746 PRK06746
peptide chain release factor 2; Provisional
 122-353 7.50e-63

peptide chain release factor 2; Provisional


Pssm-ID: 75726 [Multi-domain]  Cd Length: 326  Bit Score: 204.58  E-value: 7.50e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 122 FWDDRTKAQETLSSLNDLKDrmrLLSEFKTMVEDAETIvKLTEEM--DSTDVSLLEEAMGIIKELNKSLDKFELTQLLSG 199
Cdd:PRK06746    6 FWDDQQGAQAVINEANALKD---MVGKFRQLDETFENL-EITHELlkEEYDEDLHEELESEVKGLIQEMNEYELQLLLSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 200 PYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRI 279
Cdd:PRK06746   82 PYDKNNAILELHPGAGGTESQDWGSMLLRMYTRWAEKRGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063734601 280 VRQSPFNSKGLRQTSFSGVEVMPLLPEEaVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRC 353
Cdd:PRK06746  162 VRISPFDSSGRRHTSFVSCEVVPEFNDE-VEIEVRTEDLKIDTYRASGAGGQHVNTTDSAVRITHTPTNTVVTC 234
prfA PRK00591
peptide chain release factor 1; Validated
 101-365 7.28e-49

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 168.72  E-value: 7.28e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 101 ANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETivklTEEM--DSTDVSLLEEAM 178
Cdd:PRK00591    6 DKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKQAQEDLEE----AKEMleEESDPEMREMAK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 179 GIIKELNKSLDKFE--LTQLL--SGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGI 254
Cdd:PRK00591   82 EELKELEERLEELEeeLKILLlpKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERQGWKVEILSASEGELGGY 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 255 KSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEeaVGIEIPEEDLDISFTRAGGKGGQNVN 334
Cdd:PRK00591  162 KEVIAEISGDGVYSKLKFESGVHRVQRVPATESQGRIHTSAATVAVLPEAEE--VEVEINPKDLRIDTFRSSGAGGQHVN 239

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1063734601 335 KVETAVRITHIPTGVAVRCTDrvgccrgEKS 365
Cdd:PRK00591  240 TTDSAVRITHLPTGIVVECQD-------ERS 263
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 103-365 1.48e-44

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 157.47  E-value: 1.48e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 103 LQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETivklTEEM--DSTDVSLLEEAMGI 180
Cdd:COG0216     6 LEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEE----AKELleEESDPEMREMAKEE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 181 IKELNKSLDKFE--LTQLL--SGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKS 256
Cdd:COG0216    82 LEELEARLEELEeeLKILLlpKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGYKE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601 257 ATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPllpE-EAVGIEIPEEDLDISFTRAGGKGGQNVNK 335
Cdd:COG0216   162 VIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLP---EaEEVDVEINPKDLRIDTFRSSGAGGQHVNT 238

                         250       260       270
                  ....*....|....*....|....*....|
gi 1063734601 336 VETAVRITHIPTGVAVRCTDrvgccrgEKS 365
Cdd:COG0216   239 TDSAVRITHLPTGIVVECQD-------ERS 261
PCRF smart00937
This domain is found in peptide chain release factors;
161-273 4.34e-39

This domain is found in peptide chain release factors;


Pssm-ID: 214923 [Multi-domain]  Cd Length: 116  Bit Score: 135.67  E-value: 4.34e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063734601  161 KLTEEMDstDVSLLEEAMGIIKELN----KSLDKFELTQLLSG-PYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGE 235
Cdd:smart00937   1 ELLEEEE--DDEMRELAEEELEELEaeleEELEELLKLLLLPKdPNDDKNAILEIRAGAGGDEAALFAGDLLRMYLRYAE 78

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1063734601  236 KQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGE 273
Cdd:smart00937  79 RKGWKVEVLDESEGELGGIKEATLKISGEGAYGKLKFE 116
RF-1 pfam00472
RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and ...
 307-355 6.07e-23

RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. The domain contains a highly conserved motif GGQ, where the glutamine is thought to coordinate the water that mediates the hydrolysis.


Pssm-ID: 459823 [Multi-domain]  Cd Length: 111  Bit Score: 92.49  E-value: 6.07e-23
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1063734601 307 EAVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTD 355
Cdd:pfam00472   1 DEIEIEIDPKDLRIDTFRSSGAGGQHVNKTDSAVRLTHIPTGIVVKCQD 49
PrfB COG1186
Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein ...
 311-353 5.86e-17

Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein chain release factor PrfB is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440799 [Multi-domain]  Cd Length: 140  Bit Score: 76.71  E-value: 5.86e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063734601 311 IEIPEEDLDISFTRAGGKGGQNVNKVETAVRITH------------IPTGVAVRC 353
Cdd:COG1186    21 IEIPESDLRIDTYRASGAGGQNVNKVSSAVRLTHdiassslpdsrlTPGGIVVKA 75
PRK09256 PRK09256
aminoacyl-tRNA hydrolase;
311-340 1.11e-09

aminoacyl-tRNA hydrolase;


Pssm-ID: 181730 [Multi-domain]  Cd Length: 138  Bit Score: 56.31  E-value: 1.11e-09
                          10        20        30
                  ....*....|....*....|....*....|
gi 1063734601 311 IEIPEEDLDISFTRAGGKGGQNVNKVETAV 340
Cdd:PRK09256    8 LVIPENELEWRFIRASGPGGQNVNKVSTAV 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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