NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1063732299|ref|NP_001330040|]
View 

SART-1 family [Arabidopsis thaliana]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SART-1 super family cl25746
SART-1 family; SART-1 is a protein involved in cell cycle arrest and pre-mRNA splicing. It has ...
 178-727 1.34e-42

SART-1 family; SART-1 is a protein involved in cell cycle arrest and pre-mRNA splicing. It has been shown to be a component of U4/U6 x U5 tri-snRNP complex in human, Schizosaccharomyces pombe and Saccharomyces cerevisiae. SART-1 is a known tumour antigen in a range of cancers recognized by T cells.


The actual alignment was detected with superfamily member pfam03343:

Pssm-ID: 460888 [Multi-domain]  Cd Length: 569  Bit Score: 163.67  E-value: 1.34e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 178 LQNRILKMREERKKKA----------EDASDALSWVARSRKIEEKrnAEKQRAQQLSRIFEEQDNLNQGENEDGEdgEHL 247
Cdd:pfam03343   3 LKEKIKKAREKRERNAklegkglgedDEDDDAKAWVKKSKKRQKA--IAKAKARELEEELGEEEAEKAAQAEYTS--KDL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 248 SGVKVLHGLEKVVEGGAVILTLKDQSVLTDgdvnNEIDMLENVEIGEQKRRNEAYEAAKKKKGiYDDKFNDDPG-AEKKM 326
Cdd:pfam03343  79 AGLKVGHDLDDFLEGEEQILTLKDTGVLLD----EEEDELENVNLAEKEKLKKNLELKKKKPG-YDPYDDDEDGeGEKGI 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 327 LPQYDE----AATDEGIFLDAKGRFTGEAEKKLEELRKRIQGQTthtfEDLNSSA-KVSSDYFSQEEMLKFKKPKKKkql 401
Cdd:pfam03343 154 LSKYDEeidgKKKKKGFTLDGQGSTAEEREALAEEIAEKLKKQL----LSLDYLKlEPASDYLDESEIFKFKKPKKK--- 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 402 rkkdkldlsmleaeavasglgaedlgSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPfkRDEDE 481
Cdd:pfam03343 227 --------------------------KKKKTRKKAKKDDDLLILFPGEADLGLPSDDDDMDVDSEPIGVERLT--RDVIE 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 482 SMVladDAEDLYKSLEKARRLALIKKEEagSGPQAVAHLVAsstnqTTDDNTTTGDETQENTVVFTEMGDFVWGLQ-REN 560
Cdd:pfam03343 279 NFV---DDDDLQAALARQRRAALKKRKK--LRPEDIARQLK-----EEREEEEEDEEEEDGGLVIDETSEFVRNLGaIPT 348

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 561 DVRKPESEDVFMEEDVAPKAPVEVKEEHPDGLTEVNDTDMDAAEDSSDTKEITPDENIH-------------EVAVGKGL 627
Cdd:pfam03343 349 YERAGNRRKPVPVSPVADEEDEEEDMFEEDGDVDMEDESYEDAEEEEAEEEAREEEESDedladitgtgleeEPTVSQGL 428

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 628 SGALKLLKDRGTLKEKVEWGG----------------------RNMDKKKSKLVGIVDDDGGKEsKDKESK--------- 676
Cdd:pfam03343 429 GATLALLRQKGLLEESTAEELererrqkflaeklrlereleeqARLQRERDRASGRLDKMSARE-REEYARrenrqreqq 507

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063732299 677 ------DRFK-----DIRIERTDEFGRTLTPKEAFRLLSHKFHGKGPGKMKEEKRMKQYQEE 727
Cdd:pfam03343 508 earplaEFFEkdykpDVKLKYVDEFGRELNQKEAFKHLSHQFHGKGSGKMKTEKRLKKIEEE 569
SF-CC1 super family cl36939
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 38-148 1.22e-12

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


The actual alignment was detected with superfamily member TIGR01622:

Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 71.10  E-value: 1.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  38 RSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNE 117
Cdd:TIGR01622   1 RYRDRERERLRDSSSAGDRDRRRDKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPREKRRRRG 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1063732299 118 KEKDKDRARVKERASKKSHEDD-DETHKAAER 148
Cdd:TIGR01622  81 DSYRRRRDDRRSRREKPRARDGtPEPLTEDER 112
 
Name Accession Description Interval E-value
SART-1 pfam03343
SART-1 family; SART-1 is a protein involved in cell cycle arrest and pre-mRNA splicing. It has ...
 178-727 1.34e-42

SART-1 family; SART-1 is a protein involved in cell cycle arrest and pre-mRNA splicing. It has been shown to be a component of U4/U6 x U5 tri-snRNP complex in human, Schizosaccharomyces pombe and Saccharomyces cerevisiae. SART-1 is a known tumour antigen in a range of cancers recognized by T cells.


Pssm-ID: 460888 [Multi-domain]  Cd Length: 569  Bit Score: 163.67  E-value: 1.34e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 178 LQNRILKMREERKKKA----------EDASDALSWVARSRKIEEKrnAEKQRAQQLSRIFEEQDNLNQGENEDGEdgEHL 247
Cdd:pfam03343   3 LKEKIKKAREKRERNAklegkglgedDEDDDAKAWVKKSKKRQKA--IAKAKARELEEELGEEEAEKAAQAEYTS--KDL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 248 SGVKVLHGLEKVVEGGAVILTLKDQSVLTDgdvnNEIDMLENVEIGEQKRRNEAYEAAKKKKGiYDDKFNDDPG-AEKKM 326
Cdd:pfam03343  79 AGLKVGHDLDDFLEGEEQILTLKDTGVLLD----EEEDELENVNLAEKEKLKKNLELKKKKPG-YDPYDDDEDGeGEKGI 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 327 LPQYDE----AATDEGIFLDAKGRFTGEAEKKLEELRKRIQGQTthtfEDLNSSA-KVSSDYFSQEEMLKFKKPKKKkql 401
Cdd:pfam03343 154 LSKYDEeidgKKKKKGFTLDGQGSTAEEREALAEEIAEKLKKQL----LSLDYLKlEPASDYLDESEIFKFKKPKKK--- 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 402 rkkdkldlsmleaeavasglgaedlgSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPfkRDEDE 481
Cdd:pfam03343 227 --------------------------KKKKTRKKAKKDDDLLILFPGEADLGLPSDDDDMDVDSEPIGVERLT--RDVIE 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 482 SMVladDAEDLYKSLEKARRLALIKKEEagSGPQAVAHLVAsstnqTTDDNTTTGDETQENTVVFTEMGDFVWGLQ-REN 560
Cdd:pfam03343 279 NFV---DDDDLQAALARQRRAALKKRKK--LRPEDIARQLK-----EEREEEEEDEEEEDGGLVIDETSEFVRNLGaIPT 348

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 561 DVRKPESEDVFMEEDVAPKAPVEVKEEHPDGLTEVNDTDMDAAEDSSDTKEITPDENIH-------------EVAVGKGL 627
Cdd:pfam03343 349 YERAGNRRKPVPVSPVADEEDEEEDMFEEDGDVDMEDESYEDAEEEEAEEEAREEEESDedladitgtgleeEPTVSQGL 428

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 628 SGALKLLKDRGTLKEKVEWGG----------------------RNMDKKKSKLVGIVDDDGGKEsKDKESK--------- 676
Cdd:pfam03343 429 GATLALLRQKGLLEESTAEELererrqkflaeklrlereleeqARLQRERDRASGRLDKMSARE-REEYARrenrqreqq 507

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063732299 677 ------DRFK-----DIRIERTDEFGRTLTPKEAFRLLSHKFHGKGPGKMKEEKRMKQYQEE 727
Cdd:pfam03343 508 earplaEFFEkdykpDVKLKYVDEFGRELNQKEAFKHLSHQFHGKGSGKMKTEKRLKKIEEE 569
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 38-148 1.22e-12

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 71.10  E-value: 1.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  38 RSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNE 117
Cdd:TIGR01622   1 RYRDRERERLRDSSSAGDRDRRRDKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPREKRRRRG 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1063732299 118 KEKDKDRARVKERASKKSHEDD-DETHKAAER 148
Cdd:TIGR01622  81 DSYRRRRDDRRSRREKPRARDGtPEPLTEDER 112
PTZ00121 PTZ00121
MAEBL; Provisional
 31-509 1.20e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 1.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   31 RRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREK-DKSRDRVKEKDKEKERNRHKD 109
Cdd:PTZ00121  1335 KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKADELKKAA 1414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  110 RENERDNEKEKDKDRARVKERASKKSHEDD--DETHKAAERYEHSDNrGLNEGGDNVDAASSGKEASALDLQNRILKMRE 187
Cdd:PTZ00121  1415 AAKKKADEAKKKAEEKKKADEAKKKAEEAKkaDEAKKKAEEAKKAEE-AKKKAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  188 ERKKKAED---ASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGENEDgedgehlsgvkvlhglekvvegga 264
Cdd:PTZ00121  1494 EAKKKADEakkAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD------------------------ 1549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  265 viltlkdqsvltdgdvnnEIDMLENVEIGEQKRRNEAYEAAKKKKGIYDDKFNDDPGAEKKMLPQYDEAATDEGIFLDAK 344
Cdd:PTZ00121  1550 ------------------ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE 1611

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  345 GRFTGEAEKKLEELRKRIQGQTTHTFEDLNSSAKVSsdyfSQEEMLKFKKPKKKKQLRKKDKLDLSMLEAEAVASglgAE 424
Cdd:PTZ00121  1612 AKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK----KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK---AE 1684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  425 DLGSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPFKRDEDESmvlADDAEDLYKSLEKARRLAL 504
Cdd:PTZ00121  1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED---KKKAEEAKKDEEEKKKIAH 1761


                   ....*
gi 1063732299  505 IKKEE 509
Cdd:PTZ00121  1762 LKKEE 1766
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-501 1.52e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 1.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   4 EKSKSRHEIREERADYEGSpvREHRDGRRKEkdhrSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRD 83
Cdd:COG1196   285 EAQAEEYELLAELARLEQD--IARLEERRRE----LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  84 KEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRglneggDN 163
Cdd:COG1196   359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL------AE 432

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 164 VDAASSGKEASALDLQNRILKMREERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGENEDGED 243
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 244 GEHLSGVKVLHGLEKVVEGGAVILTLKDQSVLTDGDVNNEIDMLENVE--IGEQKRRNEAYEAAKKKKGIYDDKFNDDPG 321
Cdd:COG1196   513 ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaIEYLKAAKAGRATFLPLDKIRARAALAAAL 592

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 322 AEKKMLPQYDEAATDEGIFLDAKGRFTGEAEKKLEELRKRIQGQTTH--TFEDLNSSAKVSSDYFSQEEMLKFKKPKKKK 399
Cdd:COG1196   593 ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAvtLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 400 QLRKKDKLDLSMLEAEAVASGLGAEDLGSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPFKRDE 479
Cdd:COG1196   673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                         490       500
                  ....*....|....*....|..
gi 1063732299 480 DESMVLADDAEDLYKSLEKARR 501
Cdd:COG1196   753 LEELPEPPDLEELERELERLER 774
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 4-163 2.55e-06

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 51.06  E-value: 2.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   4 EKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREkiRDKDHRRDKEKERDRKRSRDEDTEkeisRGRD 83
Cdd:PRK12678  123 EAAQARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEEEE--RDERRRRGDREDRQAEAERGERGR----REER 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  84 KEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAE----RYEHSDNRGLNE 159
Cdd:PRK12678  197 GRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGrrgrRFRDRDRRGRRG 276


                  ....
gi 1063732299 160 GGDN 163
Cdd:PRK12678  277 GDGG 280
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 68-137 7.30e-05

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 46.68  E-value: 7.30e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  68 RSRDEDTEKEISRGRDKEREKdksRDRVKEKDKEKERNRHKDRENERdnekekdkdrarvKERASKKSHE 137
Cdd:pfam03154 587 KKREEALEKAKREAEQKAREE---KEREKEKEKEREREREREREAER-------------AAKASSSSHE 640
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 29-177 2.11e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.90  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  29 DGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHK 108
Cdd:NF033609  675 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 754

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299 109 DRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  755 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 823
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 5.21e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.74  E-value: 5.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  699 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 778

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  779 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 835
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 6.84e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 6.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  697 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 776

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  777 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 833
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 7.51e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 7.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  693 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 772

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  773 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 829
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 29-177 9.05e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.97  E-value: 9.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  29 DGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHK 108
Cdd:NF033609  651 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 730

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299 109 DRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  731 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 799
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 1.53e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 1.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  691 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 770

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRArvKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  771 DSDSD--SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 825
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 1.73e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 782

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRArvKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  783 DSDSD--SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 837
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-177 2.10e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.82  E-value: 2.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  39 SKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEK 118
Cdd:NF033609  601 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 680

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299 119 EKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  681 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 739
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 11-245 5.25e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 40.36  E-value: 5.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   11 EIREERADYEGSPVRE------HRDGRRKEKDHRSKDK-----EKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEIS 79
Cdd:TIGR00927  639 EHTGERTGEEGERPTEaegengEESGGEAEQEGETETKgenesEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHE 718

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   80 RGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETH-KAAERYEHSDNRGLN 158
Cdd:TIGR00927  719 GETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEiQAGEDGEMKGDEGAE 798

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  159 EGGDNVDAASSGKEASALDLQNRILKMREERKKKAedasdalswvarsrkiEEKRNAEKQ-RAQQLSRIFEEQDNLNQGE 237
Cdd:TIGR00927  799 GKVEHEGETEAGEKDEHEGQSETQADDTEVKDETG----------------EQELNAENQgEAKQDEKGVDGGGGSDGGD 862


                   ....*...
gi 1063732299  238 NEDGEDGE 245
Cdd:TIGR00927  863 SEEEEEEE 870
 
Name Accession Description Interval E-value
SART-1 pfam03343
SART-1 family; SART-1 is a protein involved in cell cycle arrest and pre-mRNA splicing. It has ...
 178-727 1.34e-42

SART-1 family; SART-1 is a protein involved in cell cycle arrest and pre-mRNA splicing. It has been shown to be a component of U4/U6 x U5 tri-snRNP complex in human, Schizosaccharomyces pombe and Saccharomyces cerevisiae. SART-1 is a known tumour antigen in a range of cancers recognized by T cells.


Pssm-ID: 460888 [Multi-domain]  Cd Length: 569  Bit Score: 163.67  E-value: 1.34e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 178 LQNRILKMREERKKKA----------EDASDALSWVARSRKIEEKrnAEKQRAQQLSRIFEEQDNLNQGENEDGEdgEHL 247
Cdd:pfam03343   3 LKEKIKKAREKRERNAklegkglgedDEDDDAKAWVKKSKKRQKA--IAKAKARELEEELGEEEAEKAAQAEYTS--KDL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 248 SGVKVLHGLEKVVEGGAVILTLKDQSVLTDgdvnNEIDMLENVEIGEQKRRNEAYEAAKKKKGiYDDKFNDDPG-AEKKM 326
Cdd:pfam03343  79 AGLKVGHDLDDFLEGEEQILTLKDTGVLLD----EEEDELENVNLAEKEKLKKNLELKKKKPG-YDPYDDDEDGeGEKGI 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 327 LPQYDE----AATDEGIFLDAKGRFTGEAEKKLEELRKRIQGQTthtfEDLNSSA-KVSSDYFSQEEMLKFKKPKKKkql 401
Cdd:pfam03343 154 LSKYDEeidgKKKKKGFTLDGQGSTAEEREALAEEIAEKLKKQL----LSLDYLKlEPASDYLDESEIFKFKKPKKK--- 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 402 rkkdkldlsmleaeavasglgaedlgSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPfkRDEDE 481
Cdd:pfam03343 227 --------------------------KKKKTRKKAKKDDDLLILFPGEADLGLPSDDDDMDVDSEPIGVERLT--RDVIE 278

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 482 SMVladDAEDLYKSLEKARRLALIKKEEagSGPQAVAHLVAsstnqTTDDNTTTGDETQENTVVFTEMGDFVWGLQ-REN 560
Cdd:pfam03343 279 NFV---DDDDLQAALARQRRAALKKRKK--LRPEDIARQLK-----EEREEEEEDEEEEDGGLVIDETSEFVRNLGaIPT 348

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 561 DVRKPESEDVFMEEDVAPKAPVEVKEEHPDGLTEVNDTDMDAAEDSSDTKEITPDENIH-------------EVAVGKGL 627
Cdd:pfam03343 349 YERAGNRRKPVPVSPVADEEDEEEDMFEEDGDVDMEDESYEDAEEEEAEEEAREEEESDedladitgtgleeEPTVSQGL 428

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 628 SGALKLLKDRGTLKEKVEWGG----------------------RNMDKKKSKLVGIVDDDGGKEsKDKESK--------- 676
Cdd:pfam03343 429 GATLALLRQKGLLEESTAEELererrqkflaeklrlereleeqARLQRERDRASGRLDKMSARE-REEYARrenrqreqq 507

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063732299 677 ------DRFK-----DIRIERTDEFGRTLTPKEAFRLLSHKFHGKGPGKMKEEKRMKQYQEE 727
Cdd:pfam03343 508 earplaEFFEkdykpDVKLKYVDEFGRELNQKEAFKHLSHQFHGKGSGKMKTEKRLKKIEEE 569
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 38-148 1.22e-12

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 71.10  E-value: 1.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  38 RSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNE 117
Cdd:TIGR01622   1 RYRDRERERLRDSSSAGDRDRRRDKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPREKRRRRG 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1063732299 118 KEKDKDRARVKERASKKSHEDD-DETHKAAER 148
Cdd:TIGR01622  81 DSYRRRRDDRRSRREKPRARDGtPEPLTEDER 112
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 32-142 5.38e-12

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 69.18  E-value: 5.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  32 RKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRE 111
Cdd:TIGR01622   5 RERERLRDSSSAGDRDRRRDKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPREKRRRRGDSYR 84

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1063732299 112 NERDNEKEKD-KDRARVKERASKKSHEDDDET 142
Cdd:TIGR01622  85 RRRDDRRSRReKPRARDGTPEPLTEDERDRRT 116
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 57-187 1.32e-11

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 67.64  E-value: 1.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  57 RRDKEKERDRKRSRDEDTEKEisrgRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSH 136
Cdd:TIGR01622   2 YRDRERERLRDSSSAGDRDRR----RDKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPREKRR 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1063732299 137 EDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALDLQNRILKMRE 187
Cdd:TIGR01622  78 RRGDSYRRRRDDRRSRREKPRARDGTPEPLTEDERDRRTVFVQQLAARARE 128
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 5-127 5.59e-11

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 65.71  E-value: 5.59e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   5 KSKSRHEIREERadyegspvREHRDGRRKEKD-HRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRD 83
Cdd:TIGR01622   3 RDRERERLRDSS--------SAGDRDRRRDKGrERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPRE 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1063732299  84 KEREKDKSRDRvKEKDKEKERNRHKDRENERDNEKEKDKDRARV 127
Cdd:TIGR01622  75 KRRRRGDSYRR-RRDDRRSRREKPRARDGTPEPLTEDERDRRTV 117
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
 40-161 3.55e-10

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 63.37  E-value: 3.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  40 KDKEKDYDREKIRDKDhrRDKEKERDRKRSRDEDTEK------------EISRGRDKEREKDKSRDRVKEKDKEKERNRH 107
Cdd:TIGR01642   1 RDEEPDREREKSRGRD--RDRSSERPRRRSRDRSRFRdrhrrsrersyrEDSRPRDRRRYDSRSPRSLRYSSVRRSRDRP 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063732299 108 KDRENERD-NEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGG 161
Cdd:TIGR01642  79 RRRSRSVRsIEQHRRRLRDRSPSNQWRKDDKKRSLWDIKPPGYELVTADQAKASQ 133
SF-CC1 TIGR01622
splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors ...
 62-155 1.26e-09

splicing factor, CC1-like family; This model represents a subfamily of RNA splicing factors including the Pad-1 protein (N. crassa), CAPER (M. musculus) and CC1.3 (H.sapiens). These proteins are characterized by an N-terminal arginine-rich, low complexity domain followed by three (or in the case of 4 H. sapiens paralogs, two) RNA recognition domains (rrm: pfam00706). These splicing factors are closely related to the U2AF splicing factor family (TIGR01642). A homologous gene from Plasmodium falciparum was identified in the course of the analysis of that genome at TIGR and was included in the seed.


Pssm-ID: 273721 [Multi-domain]  Cd Length: 494  Bit Score: 61.47  E-value: 1.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  62 KERDRKRSRDEDTekeiSRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDE 141
Cdd:TIGR01622   1 RYRDRERERLRDS----SSAGDRDRRRDKGRERSRDRSRDRERSRSRRRDRHRDRDYYRGRERRSRSRRPNRRYRPREKR 76

                          90
                  ....*....|....
gi 1063732299 142 THKAAERYEHSDNR 155
Cdd:TIGR01622  77 RRRGDSYRRRRDDR 90
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
 13-131 5.76e-08

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 56.05  E-value: 5.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  13 REERADYEGSpvrEHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDteKEISRGRDKEREKDKSR 92
Cdd:TIGR01642   3 EEPDREREKS---RGRDRDRSSERPRRRSRDRSRFRDRHRRSRERSYREDSRPRDRRRYDS--RSPRSLRYSSVRRSRDR 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1063732299  93 DRVKEKDKEK-ERNRHKDRENERDNEKEKDKDRARVKERA 131
Cdd:TIGR01642  78 PRRRSRSVRSiEQHRRRLRDRSPSNQWRKDDKKRSLWDIK 117
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
 5-125 6.17e-08

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 56.05  E-value: 6.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   5 KSKSRHEIREERADYEGSPVRE-HRDGRRKEKDHRSKDKEkdyDREKIRDKDHR-RDKEKERDRKRSRDEDTEKEISRGR 82
Cdd:TIGR01642   1 RDEEPDREREKSRGRDRDRSSErPRRRSRDRSRFRDRHRR---SRERSYREDSRpRDRRRYDSRSPRSLRYSSVRRSRDR 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1063732299  83 DKEREKDKSRDrvkEKDKEKERNRHKDRENERDNEKEKDKDRA 125
Cdd:TIGR01642  78 PRRRSRSVRSI---EQHRRRLRDRSPSNQWRKDDKKRSLWDIK 117
PTZ00121 PTZ00121
MAEBL; Provisional
 31-509 1.20e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 1.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   31 RRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREK-DKSRDRVKEKDKEKERNRHKD 109
Cdd:PTZ00121  1335 KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKADELKKAA 1414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  110 RENERDNEKEKDKDRARVKERASKKSHEDD--DETHKAAERYEHSDNrGLNEGGDNVDAASSGKEASALDLQNRILKMRE 187
Cdd:PTZ00121  1415 AAKKKADEAKKKAEEKKKADEAKKKAEEAKkaDEAKKKAEEAKKAEE-AKKKAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  188 ERKKKAED---ASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGENEDgedgehlsgvkvlhglekvvegga 264
Cdd:PTZ00121  1494 EAKKKADEakkAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD------------------------ 1549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  265 viltlkdqsvltdgdvnnEIDMLENVEIGEQKRRNEAYEAAKKKKGIYDDKFNDDPGAEKKMLPQYDEAATDEGIFLDAK 344
Cdd:PTZ00121  1550 ------------------ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE 1611

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  345 GRFTGEAEKKLEELRKRIQGQTTHTFEDLNSSAKVSsdyfSQEEMLKFKKPKKKKQLRKKDKLDLSMLEAEAVASglgAE 424
Cdd:PTZ00121  1612 AKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK----KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK---AE 1684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  425 DLGSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPFKRDEDESmvlADDAEDLYKSLEKARRLAL 504
Cdd:PTZ00121  1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED---KKKAEEAKKDEEEKKKIAH 1761


                   ....*
gi 1063732299  505 IKKEE 509
Cdd:PTZ00121  1762 LKKEE 1766
U2AF_lg TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ...
 4-110 1.23e-06

U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.


Pssm-ID: 273727 [Multi-domain]  Cd Length: 509  Bit Score: 51.82  E-value: 1.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   4 EKSKSRHEIREERADYEGSPVREHRDgRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEkeisrgrD 83
Cdd:TIGR01642  18 DRSSERPRRRSRDRSRFRDRHRRSRE-RSYREDSRPRDRRRYDSRSPRSLRYSSVRRSRDRPRRRSRSVRSI-------E 89

                          90       100
                  ....*....|....*....|....*..
gi 1063732299  84 KEREKDKSRDRVKEKDKEKERNRHKDR 110
Cdd:TIGR01642  90 QHRRRLRDRSPSNQWRKDDKKRSLWDI 116
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 4-501 1.52e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 1.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   4 EKSKSRHEIREERADYEGSpvREHRDGRRKEkdhrSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRD 83
Cdd:COG1196   285 EAQAEEYELLAELARLEQD--IARLEERRRE----LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  84 KEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRglneggDN 163
Cdd:COG1196   359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL------AE 432

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 164 VDAASSGKEASALDLQNRILKMREERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGENEDGED 243
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 244 GEHLSGVKVLHGLEKVVEGGAVILTLKDQSVLTDGDVNNEIDMLENVE--IGEQKRRNEAYEAAKKKKGIYDDKFNDDPG 321
Cdd:COG1196   513 ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaIEYLKAAKAGRATFLPLDKIRARAALAAAL 592

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 322 AEKKMLPQYDEAATDEGIFLDAKGRFTGEAEKKLEELRKRIQGQTTH--TFEDLNSSAKVSSDYFSQEEMLKFKKPKKKK 399
Cdd:COG1196   593 ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAvtLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 400 QLRKKDKLDLSMLEAEAVASGLGAEDLGSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPFKRDE 479
Cdd:COG1196   673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                         490       500
                  ....*....|....*....|..
gi 1063732299 480 DESMVLADDAEDLYKSLEKARR 501
Cdd:COG1196   753 LEELPEPPDLEELERELERLER 774
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-510 2.13e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.48  E-value: 2.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   2 EVEKSKSRHEIREERADYEGSpVREHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRG 81
Cdd:COG1196   208 QAEKAERYRELKEELKELEAE-LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  82 RDKEREKDKSRDRVkEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDN--RGLNE 159
Cdd:COG1196   287 QAEEYELLAELARL-EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAelAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 160 GGDNVDAASSGKEASALDLQNRIL-KMREERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGEN 238
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEELLeALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 239 EDGEDGEHLSgVKVLHGLEKVVEGGAVILTLKDQSVLTDGDVnNEIDMLENVEIGEQKRRNEAYEAAKKKKGIYDDKFND 318
Cdd:COG1196   446 EAAEEEAELE-EEEEALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 319 DPGAEKKMLPQYDEAA--TDEGIFLDAKGRFTGEAEKKLEELRKRiQGQTTHTFEDLNSSAKVSSDYFSQEEMLKFKKPK 396
Cdd:COG1196   524 GAVAVLIGVEAAYEAAleAALAAALQNIVVEDDEVAAAAIEYLKA-AKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299 397 KKKQLRKKDKLDLSMLEAEAVASGLGAEDLGSRKDGRRQAMKEEKERIEYEKRSNAYQEAIAKADEASRLLRREQVQPFK 476
Cdd:COG1196   603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                         490       500       510
                  ....*....|....*....|....*....|....
gi 1063732299 477 RDEDESMVLADDAEDLYKSLEKARRLALIKKEEA 510
Cdd:COG1196   683 ELAERLAEEELELEEALLAEEEEERELAEAEEER 716
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 4-163 2.55e-06

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 51.06  E-value: 2.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   4 EKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREkiRDKDHRRDKEKERDRKRSRDEDTEkeisRGRD 83
Cdd:PRK12678  123 EAAQARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEEEE--RDERRRRGDREDRQAEAERGERGR----REER 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  84 KEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAE----RYEHSDNRGLNE 159
Cdd:PRK12678  197 GRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGrrgrRFRDRDRRGRRG 276


                  ....
gi 1063732299 160 GGDN 163
Cdd:PRK12678  277 GDGG 280
PTZ00121 PTZ00121
MAEBL; Provisional
 2-510 1.10e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299    2 EVEKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKI----------RDKDHRRDKEKERDRKRSRD 71
Cdd:PTZ00121  1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAeavkkaeeakKDAEEAKKAEEERNNEEIRK 1256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   72 EDTEKEISRGRD----KEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDD---DETHK 144
Cdd:PTZ00121  1257 FEEARMAHFARRqaaiKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKkkaDAAKK 1336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  145 AAERYEHSDNRGLNEGGDNVDAASSGKEASALDlqnriLKMREERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLS 224
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA-----EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELK 1411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  225 RIFEEQDNLNQGENEDGEdgehlsgVKVLHGLEKVVEGGAVILTLKDQSVLTDGDVNNEIDMLENVEIGEQKRRNEAYEA 304
Cdd:PTZ00121  1412 KAAAAKKKADEAKKKAEE-------KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  305 AK--KKKGIYDDKFNDDPGAEKKMLPQYDEAATDEGIFLDAKGRFTGEAEK-----KLEELRKRIQGQTTHTFEDLNSSA 377
Cdd:PTZ00121  1485 ADeaKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKadeakKAEEKKKADELKKAEELKKAEEKK 1564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  378 KVSSDYFSQEEMLKFKKPKKKKQLRKKDKLDLSMLEAEAvASGLGAEDLGSRKDGRRQA---MKEEKERIEYEKRSNAYQ 454
Cdd:PTZ00121  1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEE-EKKMKAEEAKKAEEAKIKAeelKKAEEEKKKVEQLKKKEA 1643

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299  455 EAIAKADEasrlLRREQVQPFKRDEDESMVLADD---AEDLYKSLEKARRLALIKKEEA 510
Cdd:PTZ00121  1644 EEKKKAEE----LKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEA 1698
PTZ00121 PTZ00121
MAEBL; Provisional
 4-361 1.23e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.37  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299    4 EKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERdRKRSRDEDTEKEISRGRD 83
Cdd:PTZ00121  1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEA-KKKAEEKKKADEAKKKAE 1441

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   84 KEREKDKSRDRVKEKDKEKERNRhKDRENERDNEKEKDKDRARVKERASKKSHEDD---DETHKAAERYEHSDNRGLNEG 160
Cdd:PTZ00121  1442 EAKKADEAKKKAEEAKKAEEAKK-KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKkkaDEAKKAAEAKKKADEAKKAEE 1520

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  161 GDNVDAASSGKEA-SALDLQNRILKMREERKKKAEDASDA--LSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGE 237
Cdd:PTZ00121  1521 AKKADEAKKAEEAkKADEAKKAEEKKKADELKKAEELKKAeeKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  238 NEDGEDGEhlsgvkvLHGLEKVVEGgavilTLKDQSVLTDGDVNNEIDMLENVEiGEQKRRNEAYEAAKKKKGIYDDKFN 317
Cdd:PTZ00121  1601 YEEEKKMK-------AEEAKKAEEA-----KIKAEELKKAEEEKKKVEQLKKKE-AEEKKKAEELKKAEEENKIKAAEEA 1667

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1063732299  318 DDPGAEKKMLPQYDEAATDEGIFLDAKGRfTGEAEKKLEELRKR 361
Cdd:PTZ00121  1668 KKAEEDKKKAEEAKKAEEDEKKAAEALKK-EAEEAKKAEELKKK 1710
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 20-165 1.69e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 48.36  E-value: 1.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  20 EGSPVREHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEisRGRDKEREKDKSRDRVKEKD 99
Cdd:PRK12678  123 EAAQARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDRED--RQAEAERGERGRREERGRDG 200

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063732299 100 KEKERNRHKDRENERDNEKEKDkdrarvkeraskksHEDDDETHKAAERYEHSDNRGLNEGGDNVD 165
Cdd:PRK12678  201 DDRDRRDRREQGDRREERGRRD--------------GGDRRGRRRRRDRRDARGDDNREDRGDRDG 252
PTZ00121 PTZ00121
MAEBL; Provisional
 4-511 1.70e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 1.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299    4 EKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREK----------------IRDKDHRRDKE-KERDR 66
Cdd:PTZ00121  1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRkfeearmahfarrqaaIKAEEARKADElKKAEE 1288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   67 KRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRA-RVKERASKKSHEDDDETHKA 145
Cdd:PTZ00121  1289 KKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAaKAEAEAAADEAEAAEEKAEA 1368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  146 AERYEHSDNRGLNEGGDNVD----AASSGKEASALDLQNRILKMREERKKKAEDASDALSWVARS----RKIEEKRNA-- 215
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKKKAEekkkADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAdeakKKAEEAKKAde 1448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  216 ------EKQRAQQLSRIFEEQDNLNQGEN--EDGEDGEHLSGvKVLHGLEKVVEGGAVILTLKDQSVLTDGDVNNEIDML 287
Cdd:PTZ00121  1449 akkkaeEAKKAEEAKKKAEEAKKADEAKKkaEEAKKADEAKK-KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA 1527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  288 ENVEigEQKRRNEAYEAAKKKKGIYDDKFNDDPGA-EKKMLPQYDEAATDEGIFLDAKGRFTGEAEKKLEELRKRIQGQT 366
Cdd:PTZ00121  1528 KKAE--EAKKADEAKKAEEKKKADELKKAEELKKAeEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  367 THTFEDLNSS--AKVSSDYFSQEEMLKFKKPKKKKQLRKKDKLDLSMLEAEAVASGLGAEDLGSRKDGRRQAMKEEKERI 444
Cdd:PTZ00121  1606 KMKAEEAKKAeeAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299  445 EYEKRSNAYQEAIAKADEASRLLRREQVQPFKRDE--DESMVLADDAEDLYKSLEKARRLALIKKEEAG 511
Cdd:PTZ00121  1686 DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEElkKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEE 1754
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 13-121 1.79e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 48.36  E-value: 1.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  13 REERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKiRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSR 92
Cdd:PRK12678  183 AEAERGERGRREERGRDGDDRDRRDRREQGDRREERGR-RDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGR 261

                          90       100
                  ....*....|....*....|....*....
gi 1063732299  93 DRVKEKDKEKERNRHKDRENERDNEKEKD 121
Cdd:PRK12678  262 RGRRFRDRDRRGRRGGDGGNEREPELRED 290
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 68-137 7.30e-05

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 46.68  E-value: 7.30e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  68 RSRDEDTEKEISRGRDKEREKdksRDRVKEKDKEKERNRHKDRENERdnekekdkdrarvKERASKKSHE 137
Cdd:pfam03154 587 KKREEALEKAKREAEQKAREE---KEREKEKEKEREREREREREAER-------------AAKASSSSHE 640
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1-226 2.10e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 2.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   1 MEVEKSKSRHEIREERADyEGSPVREHRDGRRK----EKDHRSKDKEKDYDREKIRDKD--------HRRDKEKERDRKR 68
Cdd:pfam17380 372 MEISRMRELERLQMERQQ-KNERVRQELEAARKvkilEEERQRKIQQQKVEMEQIRAEQeearqrevRRLEEERAREMER 450

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  69 SRDEDTEKEISRGRDKEREKDKSRDRVkEKDKEKERNRHKDRENERDNEKE-KDKDRARVKERASKKSHEDDDETHKAAe 147
Cdd:pfam17380 451 VRLEEQERQQQVERLRQQEEERKRKKL-ELEKEKRDRKRAEEQRRKILEKElEERKQAMIEEERKRKLLEKEMEERQKA- 528

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299 148 RYEHSDNRGLNEGGDNVDAASSGKEasaldLQNRILKMREERKKKaeDASDALSWVARSRKIEEKRNAEKQRAQQLSRI 226
Cdd:pfam17380 529 IYEEERRREAEEERRKQQEMEERRR-----IQEQMRKATEERSRL--EAMEREREMMRQIVESEKARAEYEATTPITTI 600
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 29-177 2.11e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.90  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  29 DGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHK 108
Cdd:NF033609  675 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 754

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299 109 DRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  755 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 823
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 13-141 2.29e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 44.89  E-value: 2.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  13 REERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSR 92
Cdd:PRK12678  154 TEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRR 233

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1063732299  93 DRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDE 141
Cdd:PRK12678  234 DRRDARGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGGDGGNE 282
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 4-129 3.23e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 44.12  E-value: 3.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   4 EKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRD 83
Cdd:PRK12678  159 DAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDA 238

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1063732299  84 KEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKE 129
Cdd:PRK12678  239 RGDDNREDRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGGDGGNERE 284
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 5.21e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.74  E-value: 5.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  699 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 778

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  779 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 835
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 6.84e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 6.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  697 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 776

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  777 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 833
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 7.51e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 7.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  693 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 772

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  773 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 829
PTZ00121 PTZ00121
MAEBL; Provisional
 2-239 8.19e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 8.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299    2 EVEKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRG 81
Cdd:PTZ00121  1603 EEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK 1682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   82 RDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRglnegg 161
Cdd:PTZ00121  1683 AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK------ 1756

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063732299  162 dnvdaassgkeasaldlqNRILKMREERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGENE 239
Cdd:PTZ00121  1757 ------------------KKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 4-181 8.92e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 42.97  E-value: 8.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   4 EKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRD 83
Cdd:PRK12678   67 AATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAARKAG 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  84 KEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDN 163
Cdd:PRK12678  147 EGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDR 226

                         170
                  ....*....|....*...
gi 1063732299 164 VDAASSGKEASALDLQNR 181
Cdd:PRK12678  227 RGRRRRRDRRDARGDDNR 244
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 29-177 9.05e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.97  E-value: 9.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  29 DGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHK 108
Cdd:NF033609  651 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 730

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299 109 DRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  731 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 799
PTZ00121 PTZ00121
MAEBL; Provisional
 4-243 1.09e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299    4 EKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDK---EKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISR 80
Cdd:PTZ00121  1137 EDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAkkaEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEE 1216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   81 GRDKEREKDKSRDRVKE---KDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHE--DDDETHKAAERYEHSDNR 155
Cdd:PTZ00121  1217 ARKAEDAKKAEAVKKAEeakKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEarKADELKKAEEKKKADEAK 1296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  156 GLNEGGDNVDAASSGKEASALDlqnRILKMREERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQ 235
Cdd:PTZ00121  1297 KAEEKKKADEAKKKAEEAKKAD---EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK 1373


                   ....*...
gi 1063732299  236 GENEDGED 243
Cdd:PTZ00121  1374 EEAKKKAD 1381
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 1.53e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 1.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  691 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 770

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRArvKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  771 DSDSD--SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 825
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 41-177 1.73e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 42.20  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  41 DKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEK 120
Cdd:NF033609  703 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 782

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063732299 121 DKDRArvKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  783 DSDSD--SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 837
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 39-177 2.10e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 41.82  E-value: 2.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  39 SKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEISRGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEK 118
Cdd:NF033609  601 ASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 680

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063732299 119 EKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASALD 177
Cdd:NF033609  681 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 739
PTZ00121 PTZ00121
MAEBL; Provisional
 2-239 2.26e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 2.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299    2 EVEKSKSRHEIREERADYEGSPVREHR-DGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRS--RDEDTEKEI 78
Cdd:PTZ00121  1556 ELKKAEEKKKAEEAKKAEEDKNMALRKaEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElkKAEEEKKKV 1635

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   79 SRGRDKEREKDKSRDRVKekdKEKERNRHKDRENERDNEKEKDK-DRARVKERASKKSHEDDDETHKAAERYEHSDNrgl 157
Cdd:PTZ00121  1636 EQLKKKEAEEKKKAEELK---KAEEENKIKAAEEAKKAEEDKKKaEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK--- 1709

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  158 neggdnvdaassgKEASALDLQNRILKMREERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGE 237
Cdd:PTZ00121  1710 -------------KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776


                   ..
gi 1063732299  238 NE 239
Cdd:PTZ00121  1777 KE 1778
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 11-245 5.25e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 40.36  E-value: 5.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   11 EIREERADYEGSPVRE------HRDGRRKEKDHRSKDK-----EKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEIS 79
Cdd:TIGR00927  639 EHTGERTGEEGERPTEaegengEESGGEAEQEGETETKgenesEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHE 718

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   80 RGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETH-KAAERYEHSDNRGLN 158
Cdd:TIGR00927  719 GETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEiQAGEDGEMKGDEGAE 798

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  159 EGGDNVDAASSGKEASALDLQNRILKMREERKKKAedasdalswvarsrkiEEKRNAEKQ-RAQQLSRIFEEQDNLNQGE 237
Cdd:TIGR00927  799 GKVEHEGETEAGEKDEHEGQSETQADDTEVKDETG----------------EQELNAENQgEAKQDEKGVDGGGGSDGGD 862


                   ....*...
gi 1063732299  238 NEDGEDGE 245
Cdd:TIGR00927  863 SEEEEEEE 870
PTZ00112 PTZ00112
origin recognition complex 1 protein; Provisional
 25-225 6.41e-03

origin recognition complex 1 protein; Provisional


Pssm-ID: 240274 [Multi-domain]  Cd Length: 1164  Bit Score: 40.36  E-value: 6.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   25 REHRDGRRKEKDHRSKDKEKDYDREKIRDKDHRRDKEKERDRKRSRDEDTEKEIsrgrDKEREKDKSRDRVKEKDKEKer 104
Cdd:PTZ00112   180 RNKEISNKQLKKQTNVTHTTCYDKMRRSPRNTSTIKNNTNDKNKEKNKEKDKNI----KKDRDGDKQTKRNSEKSKVQ-- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  105 NRHKDRENERDNEKEKDKDRARVK---------ERASKKSHEDDDETHKAAERYEHSDNRGLNEGGDNVDAASSGKEASA 175
Cdd:PTZ00112   254 NSHFDVRILRSYTKENKKDEKNVVsgirssvllKRKSQCLRKDSYVYSNHQKKAKTGDPKNIIHRNNGSSNSNNDDTSSS 333

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1063732299  176 LDLQNRILKMRE--ERKKKAEDASDALSwvarSRKIEEKRNAEKQRAQQLSR 225
Cdd:PTZ00112   334 NHLGSNRISNRNpsSPYKKQTTTKHTNN----TKNNKYNKTKTTQKFNHPLR 381
PTZ00121 PTZ00121
MAEBL; Provisional
 4-586 9.53e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 9.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299    4 EKSKSRHEIREERADYEGSPVREHRDGRRKEKDHRSKDKEKDYDREKI----RDKDHRRDKEKERDRKRSRDEDTEKEIS 79
Cdd:PTZ00121  1119 EAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAeearKAEDAKKAEAARKAEEVRKAEELRKAED 1198

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299   80 RGRDKEREKDKSRDRVKEKDKEKERNRHKDRENERDNEKEKDKDRARVKERASKKSHEDDDETHKAAERYEHSDNRGLNE 159
Cdd:PTZ00121  1199 ARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR 1278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  160 GGDNVDAASSGKEASALDLQNRILKMrEERKKKAEDASDALSWVARSRKIEEKRNAEKQRAQQLSRIFEEQDNLNQGENE 239
Cdd:PTZ00121  1279 KADELKKAEEKKKADEAKKAEEKKKA-DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD 1357

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  240 DGEDGEHLSGVKVLHGLEKVVEGGAVILTLKDQSVLTDGDVNNEIDMLENVEIGEQKRRNEAYEAAKKKkgiyddkfndd 319
Cdd:PTZ00121  1358 EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKK----------- 1426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  320 pGAEKKMLPQYDEAATDEGIFLDAKGRftGEAEKKLEELRKRIQgqtthtfedlnsSAKVSSDYFSQEEMLKFKKPKKKK 399
Cdd:PTZ00121  1427 -AEEKKKADEAKKKAEEAKKADEAKKK--AEEAKKAEEAKKKAE------------EAKKADEAKKKAEEAKKADEAKKK 1491

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  400 QLRKKDKLDLSMLEAEAVASGLGAEDLGSRKDGRRQAMKEEKERIEYEKRSNAYQEA--IAKADEASRLLRREQVQPFKR 477
Cdd:PTZ00121  1492 AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAdeLKKAEELKKAEEKKKAEEAKK 1571

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063732299  478 DEDESMVLADDAEDLyKSLEKARRLALIKKEEAGSGPQAVAhlvASSTNQTTDDNTTTGDETQENTVVFTEMGDFVWGLQ 557
Cdd:PTZ00121  1572 AEEDKNMALRKAEEA-KKAEEARIEEVMKLYEEEKKMKAEE---AKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK 1647

                          570       580
                   ....*....|....*....|....*....
gi 1063732299  558 RENDVRKPESEDVFMEEDVAPKAPVEVKE 586
Cdd:PTZ00121  1648 KAEELKKAEEENKIKAAEEAKKAEEDKKK 1676
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH