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Conserved domains on  [gi|1063725345|ref|NP_001329564|]
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GPCR-type G protein 2 [Arabidopsis thaliana]

Protein Classification

GPHR and ABA GPCR domain-containing protein( domain architecture ID 10576095)

GPHR N-terminal and ABA GPCR domain-containing protein containing domains similar to the N-terminal 5TM region of Golgi pH regulator (GPHR) proteins, which play vital roles in the transport of newly synthesized proteins from the Golgi to the plasma membrane, and to GPCR (G protein-coupled receptor)-type G proteins (GTG1 and GTG2), which function as abscisic acid (ABA) receptors in Arabidopsis thaliana

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GPHR_N pfam12537
The Golgi pH Regulator (GPHR) Family N-terminal; GPHR_N is the N-terminal 5TM region of the ...
 142-209 8.67e-24

The Golgi pH Regulator (GPHR) Family N-terminal; GPHR_N is the N-terminal 5TM region of the Golgi pH regulator proteins in eukaryotes. It plays vital roles in the transport of newly synthesized proteins from the Golgi to the plasma membrane, in the glycosylation of proteins along the exocytic pathway and the structural organization of the Golgi apparatus.


:

Pssm-ID: 463623  Cd Length: 68  Bit Score: 93.36  E-value: 8.67e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063725345 142 FFSMPQLVSRIGVIGVTLMAVLSGFGAVNLPYSYISLFIREIEESEIKSLERQLMQSMETCIAKKKKI 209
Cdd:pfam12537   1 FFLIENVLSRVGVIGVTLMAILSGFGAVSTPYYTFSLFLRPVTESDINNLERRLEHTRDLLAEKRKEL 68
ABA_GPCR super family cl13817
Abscisic acid G-protein coupled receptor; This domain family is found in eukaryotes, and is ...
 284-373 2.52e-16

Abscisic acid G-protein coupled receptor; This domain family is found in eukaryotes, and is typically between 177 and 216 amino acids in length. This family is part of the abscisic acid (ABA) G-protein coupled receptor. ABA is a stress hormone in plants.


The actual alignment was detected with superfamily member pfam12430:

Pssm-ID: 463577  Cd Length: 186  Bit Score: 76.49  E-value: 2.52e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063725345 284 AFSRTWKGHVQNFLGYACSIYCVYKMLKSLQSVVFKE----------AGTKDPVTMMISIFLQF-FDIGVDAALLSQYIS 352
Cdd:pfam12430   1 QRSSTLLGKLLNVFGYAFSIYCVYRILNTLLNLLPRIyshsfnlfasSSSSDPIARTLAKLLLRhFDPDLDLDAWSRQIS 80

                          90       100
                  ....*....|....*....|.
gi 1063725345 353 LLFIGMLIVISVRGFLTNLMK 373
Cdd:pfam12430  81 LLLSGVLFLCSFSSVLTTFSS 101
 
Name Accession Description Interval E-value
GPHR_N pfam12537
The Golgi pH Regulator (GPHR) Family N-terminal; GPHR_N is the N-terminal 5TM region of the ...
 142-209 8.67e-24

The Golgi pH Regulator (GPHR) Family N-terminal; GPHR_N is the N-terminal 5TM region of the Golgi pH regulator proteins in eukaryotes. It plays vital roles in the transport of newly synthesized proteins from the Golgi to the plasma membrane, in the glycosylation of proteins along the exocytic pathway and the structural organization of the Golgi apparatus.


Pssm-ID: 463623  Cd Length: 68  Bit Score: 93.36  E-value: 8.67e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063725345 142 FFSMPQLVSRIGVIGVTLMAVLSGFGAVNLPYSYISLFIREIEESEIKSLERQLMQSMETCIAKKKKI 209
Cdd:pfam12537   1 FFLIENVLSRVGVIGVTLMAILSGFGAVSTPYYTFSLFLRPVTESDINNLERRLEHTRDLLAEKRKEL 68
ABA_GPCR pfam12430
Abscisic acid G-protein coupled receptor; This domain family is found in eukaryotes, and is ...
 284-373 2.52e-16

Abscisic acid G-protein coupled receptor; This domain family is found in eukaryotes, and is typically between 177 and 216 amino acids in length. This family is part of the abscisic acid (ABA) G-protein coupled receptor. ABA is a stress hormone in plants.


Pssm-ID: 463577  Cd Length: 186  Bit Score: 76.49  E-value: 2.52e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063725345 284 AFSRTWKGHVQNFLGYACSIYCVYKMLKSLQSVVFKE----------AGTKDPVTMMISIFLQF-FDIGVDAALLSQYIS 352
Cdd:pfam12430   1 QRSSTLLGKLLNVFGYAFSIYCVYRILNTLLNLLPRIyshsfnlfasSSSSDPIARTLAKLLLRhFDPDLDLDAWSRQIS 80

                          90       100
                  ....*....|....*....|.
gi 1063725345 353 LLFIGMLIVISVRGFLTNLMK 373
Cdd:pfam12430  81 LLLSGVLFLCSFSSVLTTFSS 101
 
Name Accession Description Interval E-value
GPHR_N pfam12537
The Golgi pH Regulator (GPHR) Family N-terminal; GPHR_N is the N-terminal 5TM region of the ...
 142-209 8.67e-24

The Golgi pH Regulator (GPHR) Family N-terminal; GPHR_N is the N-terminal 5TM region of the Golgi pH regulator proteins in eukaryotes. It plays vital roles in the transport of newly synthesized proteins from the Golgi to the plasma membrane, in the glycosylation of proteins along the exocytic pathway and the structural organization of the Golgi apparatus.


Pssm-ID: 463623  Cd Length: 68  Bit Score: 93.36  E-value: 8.67e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063725345 142 FFSMPQLVSRIGVIGVTLMAVLSGFGAVNLPYSYISLFIREIEESEIKSLERQLMQSMETCIAKKKKI 209
Cdd:pfam12537   1 FFLIENVLSRVGVIGVTLMAILSGFGAVSTPYYTFSLFLRPVTESDINNLERRLEHTRDLLAEKRKEL 68
ABA_GPCR pfam12430
Abscisic acid G-protein coupled receptor; This domain family is found in eukaryotes, and is ...
 284-373 2.52e-16

Abscisic acid G-protein coupled receptor; This domain family is found in eukaryotes, and is typically between 177 and 216 amino acids in length. This family is part of the abscisic acid (ABA) G-protein coupled receptor. ABA is a stress hormone in plants.


Pssm-ID: 463577  Cd Length: 186  Bit Score: 76.49  E-value: 2.52e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063725345 284 AFSRTWKGHVQNFLGYACSIYCVYKMLKSLQSVVFKE----------AGTKDPVTMMISIFLQF-FDIGVDAALLSQYIS 352
Cdd:pfam12430   1 QRSSTLLGKLLNVFGYAFSIYCVYRILNTLLNLLPRIyshsfnlfasSSSSDPIARTLAKLLLRhFDPDLDLDAWSRQIS 80

                          90       100
                  ....*....|....*....|.
gi 1063725345 353 LLFIGMLIVISVRGFLTNLMK 373
Cdd:pfam12430  81 LLLSGVLFLCSFSSVLTTFSS 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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