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Conserved domains on  [gi|1063704822|ref|NP_001325074|]
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receptor like protein 21 [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1000136)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
 12-712 3.44e-53

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 199.69  E-value: 3.44e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822  12 CQYLIWVMLLLGQLHGCTSciEKEREALLELKKylmsrSRESGLDYvLPTWtnDTKSDCCQWDGIKCNRTSG-RVIELSV 90
Cdd:PLN00113    9 CPYLIFMLFFLFLNFSMLH--AEELELLLSFKS-----SINDPLKY-LSNW--NSSADVCLWQGITCNNSSRvVSIDLSG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822  91 GDMyfkeSSPLNLSLLH-PFeeVRSLNLSTEgynefngffddvegyrSLSGLRNLKIMDLSTnyfnystfpflnaatSLT 169
Cdd:PLN00113   79 KNI----SGKISSAIFRlPY--IQTINLSNN----------------QLSGPIPDDIFTTSS---------------SLR 121

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 170 TLILTYNEMDGPFPiKGlkDLTNLELLDLRANKLNGSM-QELIHLKKLKALDLSSNKFSSSMELQeLQNLINLEVLGLAQ 248
Cdd:PLN00113  122 YLNLSNNNFTGSIP-RG--SIPNLETLDLSNNMLSGEIpNDIGSFSSLKVLDLGGNVLVGKIPNS-LTNLTSLEFLTLAS 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 249 NHVDGPIPIEVfCKLKNLRDLDLKGNHFVGQIPLCLGSLKKLRVLDLSSNQLSGDLPSSFSSLESLEYLSLSDNNFDGSF 328
Cdd:PLN00113  198 NQLVGQIPREL-GQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPI 276

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 329 SlNPLTNLTNLKLFKLSSRShtiqvkmestwqpnfqLSvvvlrfcslEKIPSFLLYQKKLRLVDLSSNNLSGNIPTwLLT 408
Cdd:PLN00113  277 P-PSIFSLQKLISLDLSDNS----------------LS---------GEIPELVIQLQNLEILHLFSNNFTGKIPV-ALT 329

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 409 NNPELEVLQLQNNSFTiFPIPTMV---HNLQIFDFSANNI-GKFPDKMDHAlPNLVRLNGSNNGFQGYFPTSIGEMKNIS 484
Cdd:PLN00113  330 SLPRLQVLQLWSNKFS-GEIPKNLgkhNNLTVLDLSTNNLtGEIPEGLCSS-GNLFKLILFSNSLEGEIPKSLGACRSLR 407

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 485 FLDLSYNNFSGKLPRSFvTGCVSIMFLKLSHNKFSGRFLPRETNFPSLDVLRMDNNLFTGNIGGgLSNSTMLRILDMSNN 564
Cdd:PLN00113  408 RVRLQDNSFSGELPSEF-TKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPD-SFGSKRLENLDLSRN 485

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 565 GLSGAIPRwlfefpyldyvlisnnflegtippSLLGMPFLSFLDLSGNQFSGALPSHVDSelgiymflhnnnftgpipdt 644
Cdd:PLN00113  486 QFSGAVPR------------------------KLGSLSELMQLKLSENKLSGEIPDELSS-------------------- 521

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063704822 645 lLKSVQILDLRNNKLSGSIP-QFDDTQSINILLLKGNNLTGSIPRELCDLSNVRLLDLSDNKLNGVIPS 712
Cdd:PLN00113  522 -CKKLVSLDLSHNQLSGQIPaSFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPS 589
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 12-712 3.44e-53

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 199.69  E-value: 3.44e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822  12 CQYLIWVMLLLGQLHGCTSciEKEREALLELKKylmsrSRESGLDYvLPTWtnDTKSDCCQWDGIKCNRTSG-RVIELSV 90
Cdd:PLN00113    9 CPYLIFMLFFLFLNFSMLH--AEELELLLSFKS-----SINDPLKY-LSNW--NSSADVCLWQGITCNNSSRvVSIDLSG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822  91 GDMyfkeSSPLNLSLLH-PFeeVRSLNLSTEgynefngffddvegyrSLSGLRNLKIMDLSTnyfnystfpflnaatSLT 169
Cdd:PLN00113   79 KNI----SGKISSAIFRlPY--IQTINLSNN----------------QLSGPIPDDIFTTSS---------------SLR 121

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 170 TLILTYNEMDGPFPiKGlkDLTNLELLDLRANKLNGSM-QELIHLKKLKALDLSSNKFSSSMELQeLQNLINLEVLGLAQ 248
Cdd:PLN00113  122 YLNLSNNNFTGSIP-RG--SIPNLETLDLSNNMLSGEIpNDIGSFSSLKVLDLGGNVLVGKIPNS-LTNLTSLEFLTLAS 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 249 NHVDGPIPIEVfCKLKNLRDLDLKGNHFVGQIPLCLGSLKKLRVLDLSSNQLSGDLPSSFSSLESLEYLSLSDNNFDGSF 328
Cdd:PLN00113  198 NQLVGQIPREL-GQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPI 276

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 329 SlNPLTNLTNLKLFKLSSRShtiqvkmestwqpnfqLSvvvlrfcslEKIPSFLLYQKKLRLVDLSSNNLSGNIPTwLLT 408
Cdd:PLN00113  277 P-PSIFSLQKLISLDLSDNS----------------LS---------GEIPELVIQLQNLEILHLFSNNFTGKIPV-ALT 329

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 409 NNPELEVLQLQNNSFTiFPIPTMV---HNLQIFDFSANNI-GKFPDKMDHAlPNLVRLNGSNNGFQGYFPTSIGEMKNIS 484
Cdd:PLN00113  330 SLPRLQVLQLWSNKFS-GEIPKNLgkhNNLTVLDLSTNNLtGEIPEGLCSS-GNLFKLILFSNSLEGEIPKSLGACRSLR 407

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 485 FLDLSYNNFSGKLPRSFvTGCVSIMFLKLSHNKFSGRFLPRETNFPSLDVLRMDNNLFTGNIGGgLSNSTMLRILDMSNN 564
Cdd:PLN00113  408 RVRLQDNSFSGELPSEF-TKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPD-SFGSKRLENLDLSRN 485

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 565 GLSGAIPRwlfefpyldyvlisnnflegtippSLLGMPFLSFLDLSGNQFSGALPSHVDSelgiymflhnnnftgpipdt 644
Cdd:PLN00113  486 QFSGAVPR------------------------KLGSLSELMQLKLSENKLSGEIPDELSS-------------------- 521

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063704822 645 lLKSVQILDLRNNKLSGSIP-QFDDTQSINILLLKGNNLTGSIPRELCDLSNVRLLDLSDNKLNGVIPS 712
Cdd:PLN00113  522 -CKKLVSLDLSHNQLSGQIPaSFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPS 589
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
95-450 7.56e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 80.75  E-value: 7.56e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822  95 FKESSPLNLSLLHPFEEVRSLNLSTEGYNEFNGFFDDVEGYRSLSGLRNLKIMDLSTNyfnystfPFLNAATSLTTLILT 174
Cdd:COG4886    49 LTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLS 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 175 YNEMDGPFPikGLKDLTNLELLDLRANKLNGSMQELIHLKKLKALDLSSNKFSSsmeL-QELQNLINLEVLGLAQNHVDg 253
Cdd:COG4886   122 GNQLTDLPE--ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTD---LpEELGNLTNLKELDLSNNQIT- 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 254 PIPiEVFCKLKNLRDLDLKGNHfVGQIPLCLGSLKKLRVLDLSSNQLSgDLPSSFSSLESLeYLSLSDNNFDgsfSLNPL 333
Cdd:COG4886   196 DLP-EPLGNLTNLEELDLSGNQ-LTDLPEPLANLTNLETLDLSNNQLT-DLPELGNLTNLE-ELDLSNNQLT---DLPPL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 334 TNLTNLKLFKLSSRSHTIQVKMESTWQPNFQLSVVVLRFCSLEKIPSFLLYQKKLRLVDLSSNNLSGNIPTWLLTNNPEL 413
Cdd:COG4886   269 ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLA 348

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1063704822 414 EVLQLQNNSFTIFPIPTMVHNLQIFDFSANNIGKFPD 450
Cdd:COG4886   349 LLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALL 385
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 133-301 4.09e-08

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 55.82  E-value: 4.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 133 EGYRSLSGLRNLkimDLSTNYFNYSTFPFLNAATSLTTL---ILTYNEMD---GPFPIKGLKDLT-NLELLDLRANKL-N 204
Cdd:cd00116    75 QGLTKGCGLQEL---DLSDNALGPDGCGVLESLLRSSSLqelKLNNNGLGdrgLRLLAKGLKDLPpALEKLVLGRNRLeG 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 205 GSMQELihlkklkALDLSSNKfsssmelqelqnliNLEVLGLAQNHVDGPiPIEVFCK----LKNLRDLDLKGNHF---- 276
Cdd:cd00116   152 ASCEAL-------AKALRANR--------------DLKELNLANNGIGDA-GIRALAEglkaNCNLEVLDLNNNGLtdeg 209

                         170       180
                  ....*....|....*....|....*
gi 1063704822 277 VGQIPLCLGSLKKLRVLDLSSNQLS 301
Cdd:cd00116   210 ASALAETLASLKSLEVLNLGDNNLT 234
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 35-79 4.59e-05

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 41.13  E-value: 4.59e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1063704822  35 EREALLELKKYLmsrsreSGLDYVLPTWTNDTkSDCCQWDGIKCN 79
Cdd:pfam08263   4 DGQALLAFKSSL------NDPPGALSSWNSSS-SDPCSWTGVTCD 41
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 12-712 3.44e-53

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 199.69  E-value: 3.44e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822  12 CQYLIWVMLLLGQLHGCTSciEKEREALLELKKylmsrSRESGLDYvLPTWtnDTKSDCCQWDGIKCNRTSG-RVIELSV 90
Cdd:PLN00113    9 CPYLIFMLFFLFLNFSMLH--AEELELLLSFKS-----SINDPLKY-LSNW--NSSADVCLWQGITCNNSSRvVSIDLSG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822  91 GDMyfkeSSPLNLSLLH-PFeeVRSLNLSTEgynefngffddvegyrSLSGLRNLKIMDLSTnyfnystfpflnaatSLT 169
Cdd:PLN00113   79 KNI----SGKISSAIFRlPY--IQTINLSNN----------------QLSGPIPDDIFTTSS---------------SLR 121

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 170 TLILTYNEMDGPFPiKGlkDLTNLELLDLRANKLNGSM-QELIHLKKLKALDLSSNKFSSSMELQeLQNLINLEVLGLAQ 248
Cdd:PLN00113  122 YLNLSNNNFTGSIP-RG--SIPNLETLDLSNNMLSGEIpNDIGSFSSLKVLDLGGNVLVGKIPNS-LTNLTSLEFLTLAS 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 249 NHVDGPIPIEVfCKLKNLRDLDLKGNHFVGQIPLCLGSLKKLRVLDLSSNQLSGDLPSSFSSLESLEYLSLSDNNFDGSF 328
Cdd:PLN00113  198 NQLVGQIPREL-GQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPI 276

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 329 SlNPLTNLTNLKLFKLSSRShtiqvkmestwqpnfqLSvvvlrfcslEKIPSFLLYQKKLRLVDLSSNNLSGNIPTwLLT 408
Cdd:PLN00113  277 P-PSIFSLQKLISLDLSDNS----------------LS---------GEIPELVIQLQNLEILHLFSNNFTGKIPV-ALT 329

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 409 NNPELEVLQLQNNSFTiFPIPTMV---HNLQIFDFSANNI-GKFPDKMDHAlPNLVRLNGSNNGFQGYFPTSIGEMKNIS 484
Cdd:PLN00113  330 SLPRLQVLQLWSNKFS-GEIPKNLgkhNNLTVLDLSTNNLtGEIPEGLCSS-GNLFKLILFSNSLEGEIPKSLGACRSLR 407

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 485 FLDLSYNNFSGKLPRSFvTGCVSIMFLKLSHNKFSGRFLPRETNFPSLDVLRMDNNLFTGNIGGgLSNSTMLRILDMSNN 564
Cdd:PLN00113  408 RVRLQDNSFSGELPSEF-TKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPD-SFGSKRLENLDLSRN 485

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 565 GLSGAIPRwlfefpyldyvlisnnflegtippSLLGMPFLSFLDLSGNQFSGALPSHVDSelgiymflhnnnftgpipdt 644
Cdd:PLN00113  486 QFSGAVPR------------------------KLGSLSELMQLKLSENKLSGEIPDELSS-------------------- 521

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063704822 645 lLKSVQILDLRNNKLSGSIP-QFDDTQSINILLLKGNNLTGSIPRELCDLSNVRLLDLSDNKLNGVIPS 712
Cdd:PLN00113  522 -CKKLVSLDLSHNQLSGQIPaSFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPS 589
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 215-734 6.10e-53

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 199.30  E-value: 6.10e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 215 KLKALDLSSNKFSSSMELQELQnLINLEVLGLAQNHVDGPIPIEVFCKLKNLRDLDLKGNHFVGQIPLclGSLKKLRVLD 294
Cdd:PLN00113   70 RVVSIDLSGKNISGKISSAIFR-LPYIQTINLSNNQLSGPIPDDIFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLD 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 295 LSSNQLSGDLPSSFSSLESLEYLSLSDNNFDGSFSlNPLTNLTNLKLFKLSSRSHTIQVKMESTWQPNfqLSVVVLRFCS 374
Cdd:PLN00113  147 LSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIP-NSLTNLTSLEFLTLASNQLVGQIPRELGQMKS--LKWIYLGYNN 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 375 LE-KIPSFLLYQKKLRLVDLSSNNLSGNIPTwLLTNNPELEVLQLQNNSFTiFPIPTMVHNLQifdfsannigkfpdkmd 453
Cdd:PLN00113  224 LSgEIPYEIGGLTSLNHLDLVYNNLTGPIPS-SLGNLKNLQYLFLYQNKLS-GPIPPSIFSLQ----------------- 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 454 halpNLVRLNGSNNGFQGYFPTSIGEMKNISFLDLSYNNFSGKLPRSfVTGCVSIMFLKLSHNKFSGRFLPRETNFPSLD 533
Cdd:PLN00113  285 ----KLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVA-LTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLT 359

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 534 VLRMDNNLFTGNIGGGLSNSTMLRILDMSNNGLSGAIPRWLFEFPYLDYVLISNNFLEGTIPPSLLGMPFLSFLDLSGNQ 613
Cdd:PLN00113  360 VLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNN 439

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 614 FSGALPSHVDSELGIYMF-LHNNNFTGPIPDTL-LKSVQILDLRNNKLSGSIPQ-FDDTQSINILLLKGNNLTGSIPREL 690
Cdd:PLN00113  440 LQGRINSRKWDMPSLQMLsLARNKFFGGLPDSFgSKRLENLDLSRNQFSGAVPRkLGSLSELMQLKLSENKLSGEIPDEL 519

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*..
gi 1063704822 691 CDLSNVRLLDLSDNKLNGVIPSCLSN---LSFGRLQEDAMALNIPPS 734
Cdd:PLN00113  520 SSCKKLVSLDLSHNQLSGQIPASFSEmpvLSQLDLSQNQLSGEIPKN 566
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 391-740 1.97e-34

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 141.91  E-value: 1.97e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 391 VDLSSNNLSGNIptwlltnnpelevlqlqnnSFTIFPIPTmvhnLQIFDFSANNI-GKFPDKMDHALPNLVRLNGSNNGF 469
Cdd:PLN00113   74 IDLSGKNISGKI-------------------SSAIFRLPY----IQTINLSNNQLsGPIPDDIFTTSSSLRYLNLSNNNF 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 470 QGYFPTsiGEMKNISFLDLSYNNFSGKLPRSfVTGCVSIMFLKLSHNKFSGRFLPRETNFPSLDVLRMDNNLFTGNIGGG 549
Cdd:PLN00113  131 TGSIPR--GSIPNLETLDLSNNMLSGEIPND-IGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRE 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 550 LSNSTMLRILDMSNNGLSGAIPRWLFEFPYLDYVLISNNFLEGTIPPSLLGMPFLSFLDLSGNQFSGALPSHVDS----- 624
Cdd:PLN00113  208 LGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSlqkli 287

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 625 --------------ELGIYM----FLH--NNNFTGPIPDTL--LKSVQILDLRNNKLSGSIPQ-FDDTQSINILLLKGNN 681
Cdd:PLN00113  288 sldlsdnslsgeipELVIQLqnleILHlfSNNFTGKIPVALtsLPRLQVLQLWSNKFSGEIPKnLGKHNNLTVLDLSTNN 367

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063704822 682 LTGSIPRELCDLSNVRLLDLSDNKLNGVIPSCLS---NLSFGRLQEDAMALNIPPSFLQTSL 740
Cdd:PLN00113  368 LTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGacrSLRRVRLQDNSFSGELPSEFTKLPL 429
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 136-476 5.32e-24

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 108.40  E-value: 5.32e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 136 RSLSGLRNLKIMDLSTNYFNYSTFPFLNAATSLTTLILTYNEMDGPFPIKgLKDLTNLELLDLRANKLNGSMQELI-HLK 214
Cdd:PLN00113  206 RELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSS-LGNLKNLQYLFLYQNKLSGPIPPSIfSLQ 284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 215 KLKALDLSSNKFSSsmELQEL-QNLINLEVLGLAQNHVDGPIPIEVfCKLKNLRDLDLKGNHFVGQIPLCLGSLKKLRVL 293
Cdd:PLN00113  285 KLISLDLSDNSLSG--EIPELvIQLQNLEILHLFSNNFTGKIPVAL-TSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVL 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 294 DLSSNQLSGDLPSSFSSLESLEYL------------------------SLSDNNFDGS----FSLNPLTNLTNLKLFKLS 345
Cdd:PLN00113  362 DLSTNNLTGEIPEGLCSSGNLFKLilfsnslegeipkslgacrslrrvRLQDNSFSGElpseFTKLPLVYFLDISNNNLQ 441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 346 SRSHTIQVKMestwqPNFQ-LSVVVLRFC----------SLEK-----------IPSFLLYQKKLRLVDLSSNNLSGNIP 403
Cdd:PLN00113  442 GRINSRKWDM-----PSLQmLSLARNKFFgglpdsfgskRLENldlsrnqfsgaVPRKLGSLSELMQLKLSENKLSGEIP 516

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 404 TWLlTNNPELEVLQLQNN--------SFTIFPIptmvhnLQIFDFSANNI-GKFPDKMDHaLPNLVRLNGSNNGFQGYFP 474
Cdd:PLN00113  517 DEL-SSCKKLVSLDLSHNqlsgqipaSFSEMPV------LSQLDLSQNQLsGEIPKNLGN-VESLVQVNISHNHLHGSLP 588


                  ..
gi 1063704822 475 TS 476
Cdd:PLN00113  589 ST 590
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
95-450 7.56e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 80.75  E-value: 7.56e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822  95 FKESSPLNLSLLHPFEEVRSLNLSTEGYNEFNGFFDDVEGYRSLSGLRNLKIMDLSTNyfnystfPFLNAATSLTTLILT 174
Cdd:COG4886    49 LTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLS 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 175 YNEMDGPFPikGLKDLTNLELLDLRANKLNGSMQELIHLKKLKALDLSSNKFSSsmeL-QELQNLINLEVLGLAQNHVDg 253
Cdd:COG4886   122 GNQLTDLPE--ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTD---LpEELGNLTNLKELDLSNNQIT- 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 254 PIPiEVFCKLKNLRDLDLKGNHfVGQIPLCLGSLKKLRVLDLSSNQLSgDLPSSFSSLESLeYLSLSDNNFDgsfSLNPL 333
Cdd:COG4886   196 DLP-EPLGNLTNLEELDLSGNQ-LTDLPEPLANLTNLETLDLSNNQLT-DLPELGNLTNLE-ELDLSNNQLT---DLPPL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 334 TNLTNLKLFKLSSRSHTIQVKMESTWQPNFQLSVVVLRFCSLEKIPSFLLYQKKLRLVDLSSNNLSGNIPTWLLTNNPEL 413
Cdd:COG4886   269 ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLA 348

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1063704822 414 EVLQLQNNSFTIFPIPTMVHNLQIFDFSANNIGKFPD 450
Cdd:COG4886   349 LLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALL 385
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
143-493 1.63e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 79.59  E-value: 1.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 143 NLKIMDLSTNYFNYSTFPFLNAATSLTTLILTYNEMDGPFPIKGLKDLTNLELLDLRANKLNGSMQELIHLKKLKALDLS 222
Cdd:COG4886    25 ILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLS 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 223 SNKfsssmelqELQNLINLEVLGLAQNHVDGpIPIEvFCKLKNLRDLDLKGNHFvGQIPLCLGSLKKLRVLDLSSNQLSg 302
Cdd:COG4886   105 GNE--------ELSNLTNLESLDLSGNQLTD-LPEE-LANLTNLKELDLSNNQL-TDLPEPLGNLTNLKSLDLSNNQLT- 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 303 DLPSSFSSLESLEYLSLSDNNFDgSFSlNPLTNLTNLKLFKLSSrshtiqvkmestwqpnfqlsvvvlrfCSLEKIPSFL 382
Cdd:COG4886   173 DLPEELGNLTNLKELDLSNNQIT-DLP-EPLGNLTNLEELDLSG--------------------------NQLTDLPEPL 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 383 LYQKKLRLVDLSSNNLSgNIPTwlLTNNPELEVLQLQNNSFTIFPIPTMVHNLQIFDFSANNIGKFPDKMDHALPNLVRL 462
Cdd:COG4886   225 ANLTNLETLDLSNNQLT-DLPE--LGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSL 301

                         330       340       350
                  ....*....|....*....|....*....|.
gi 1063704822 463 NGSNNGFQGYFPTSIGEMKNISFLDLSYNNF 493
Cdd:COG4886   302 LLLLLLLNLLELLILLLLLTTLLLLLLLLKG 332
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
316-744 2.32e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 76.13  E-value: 2.32e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 316 YLSLSDNNFDGSFSLNPLTNLTNLKLFKLSSRSHTIQVKMESTWQPNFQLSVVVLRFCSLEKIPSFLLYQKKLRLVDLSS 395
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 396 NNLSGNIPTWLLTNNPELEVLQLQNNSFTifpipTMVHNLQIFDFSANNIGKFPDKMDHaLPNLVRLNGSNNGFQgYFPT 475
Cdd:COG4886    81 LLSLLLLGLTDLGDLTNLTELDLSGNEEL-----SNLTNLESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLT-DLPE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 476 SIGEMKNISFLDLSYNNFSGkLPRSFvTGCVSIMFLKLSHNKFSgrFLPRE-TNFPSLDVLRMDNNLFTgNIGGGLSNST 554
Cdd:COG4886   154 PLGNLTNLKSLDLSNNQLTD-LPEEL-GNLTNLKELDLSNNQIT--DLPEPlGNLTNLEELDLSGNQLT-DLPEPLANLT 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 555 MLRILDMSNNGLSgAIPrWLFEFPYLDYVLISNNFLEGTipPSLLGMPFLSFLDLSGNQFSGALPSHVDSELGIYMFLHN 634
Cdd:COG4886   229 NLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLL 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 635 NNFTGPIPDTLLKSVQILDLRNNKLSGSIPQFDDTQSINILLLKGNNLTGSIPRELCDLSNVRLLDLSDNKLNGVIPSCL 714
Cdd:COG4886   305 LLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLAL 384

                         410       420       430
                  ....*....|....*....|....*....|
gi 1063704822 715 SNLSFGRLQEDAMALNIPPSFLQTSLEMEL 744
Cdd:COG4886   385 LLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
360-750 5.59e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.89  E-value: 5.59e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 360 QPNFQLSVVVLRFCSLEKIPSFLLYQKKLRLVDLSSNNLSGNIPTWLLTNNPELEVLQLQNNSFTIFPIPTMVHNLQIFD 439
Cdd:COG4886     2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 440 FSANNIGkfpDKMDHALPNLVRLNGSNNgfqgyfpTSIGEMKNISFLDLSYNNFSgKLPRSFvTGCVSIMFLKLSHNKFS 519
Cdd:COG4886    82 LSLLLLG---LTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLT-DLPEEL-ANLTNLKELDLSNNQLT 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 520 grFLPRE-TNFPSLDVLRMDNNLFTgNIGGGLSNSTMLRILDMSNNGLSgAIPRWLFEFPYLDYVLISNNFLEgTIPPSL 598
Cdd:COG4886   150 --DLPEPlGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT-DLPEPL 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 599 LGMPFLSFLDLSGNQFSgALPSHVDSELGIYMFLHNNNFTGPIPDTLLKSVQILDLRNNKLSG-SIPQFDDTQSINILLL 677
Cdd:COG4886   225 ANLTNLETLDLSNNQLT-DLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDlKLKELELLLGLNSLLL 303

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1063704822 678 KGNNLTGSIPRELCDLSNVRLLDLSDNKLNGVIPSCLSNLSFGRLQEDAMALNIPPSFLQTSLEMELYKSTFL 750
Cdd:COG4886   304 LLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLE 376
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
169-495 1.80e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 69.96  E-value: 1.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 169 TTLILTYNEMDGPFPIKGLKDLTNLELLDLRANKLNGSMQELIHLKKLKALDLSSNKFSSSMELQELQNLINLEVLGLAQ 248
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 249 NHVDGPIPIEVFCKLKNLRDLDLKGNHFvgqiplcLGSLKKLRVLDLSSNQLSgDLPSSFSSLESLEYLSLSDNNFdgSF 328
Cdd:COG4886    81 LLSLLLLGLTDLGDLTNLTELDLSGNEE-------LSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQL--TD 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 329 SLNPLTNLTNLKLFKLSSrshtiqvkmestwqpnfqlsvvvlrfCSLEKIPSFLLYQKKLRLVDLSSNNLSgNIPTWlLT 408
Cdd:COG4886   151 LPEPLGNLTNLKSLDLSN--------------------------NQLTDLPEELGNLTNLKELDLSNNQIT-DLPEP-LG 202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 409 NNPELEVLQLQNNSFTIFPIP-TMVHNLQIFDFSANNIGKFPDKMDhaLPNLVRLNGSNNGFQGYfpTSIGEMKNISFLD 487
Cdd:COG4886   203 NLTNLEELDLSGNQLTDLPEPlANLTNLETLDLSNNQLTDLPELGN--LTNLEELDLSNNQLTDL--PPLANLTNLKTLD 278


                  ....*...
gi 1063704822 488 LSYNNFSG 495
Cdd:COG4886   279 LSNNQLTD 286
PLN03150 PLN03150
hypothetical protein; Provisional
 559-664 2.21e-11

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 67.53  E-value: 2.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 559 LDMSNNGLSGAIPRWLFEFPYLDYVLISNNFLEGTIPPSLLGMPFLSFLDLSGNQFSGAlpshvdselgiymflhnnnft 638
Cdd:PLN03150  423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGS--------------------- 481

                          90       100
                  ....*....|....*....|....*...
gi 1063704822 639 gpIPDTL--LKSVQILDLRNNKLSGSIP 664
Cdd:PLN03150  482 --IPESLgqLTSLRILNLNGNSLSGRVP 507
PLN03150 PLN03150
hypothetical protein; Provisional
 632-714 8.82e-09

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 59.06  E-value: 8.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 632 LHNNNFTGPIPDTL--LKSVQILDLRNNKLSGSIP-QFDDTQSINILLLKGNNLTGSIPRELCDLSNVRLLDLSDNKLNG 708
Cdd:PLN03150  425 LDNQGLRGFIPNDIskLRHLQSINLSGNSIRGNIPpSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSG 504


                  ....*.
gi 1063704822 709 VIPSCL 714
Cdd:PLN03150  505 RVPAAL 510
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 133-301 4.09e-08

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 55.82  E-value: 4.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 133 EGYRSLSGLRNLkimDLSTNYFNYSTFPFLNAATSLTTL---ILTYNEMD---GPFPIKGLKDLT-NLELLDLRANKL-N 204
Cdd:cd00116    75 QGLTKGCGLQEL---DLSDNALGPDGCGVLESLLRSSSLqelKLNNNGLGdrgLRLLAKGLKDLPpALEKLVLGRNRLeG 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 205 GSMQELihlkklkALDLSSNKfsssmelqelqnliNLEVLGLAQNHVDGPiPIEVFCK----LKNLRDLDLKGNHF---- 276
Cdd:cd00116   152 ASCEAL-------AKALRANR--------------DLKELNLANNGIGDA-GIRALAEglkaNCNLEVLDLNNNGLtdeg 209

                         170       180
                  ....*....|....*....|....*
gi 1063704822 277 VGQIPLCLGSLKKLRVLDLSSNQLS 301
Cdd:cd00116   210 ASALAETLASLKSLEVLNLGDNNLT 234
PLN03150 PLN03150
hypothetical protein; Provisional
 532-638 5.09e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 56.36  E-value: 5.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 532 LDVLRMDNNLFTGNIGGGLSNSTMLRILDMSNNGLSGAIPRWLFEFPYLDYVLISNNFLEGTIPPSLLGMPFLSFLDLSG 611
Cdd:PLN03150  420 IDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNG 499

                          90       100
                  ....*....|....*....|....*....
gi 1063704822 612 NQFSGALPSHVDSELgiymfLHNN--NFT 638
Cdd:PLN03150  500 NSLSGRVPAALGGRL-----LHRAsfNFT 523
PLN03150 PLN03150
hypothetical protein; Provisional
 244-326 1.38e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 55.21  E-value: 1.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 244 LGLAQNHVDGPIPIEVfCKLKNLRDLDLKGNHFVGQIPLCLGSLKKLRVLDLSSNQLSGDLPSSFSSLESLEYLSLSDNN 323
Cdd:PLN03150  423 LGLDNQGLRGFIPNDI-SKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS 501


                  ...
gi 1063704822 324 FDG 326
Cdd:PLN03150  502 LSG 504
PLN03150 PLN03150
hypothetical protein; Provisional
 446-521 2.60e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 54.05  E-value: 2.60e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063704822 446 GKFPDKMDhALPNLVRLNGSNNGFQGYFPTSIGEMKNISFLDLSYNNFSGKLPRSfVTGCVSIMFLKLSHNKFSGR 521
Cdd:PLN03150  432 GFIPNDIS-KLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPES-LGQLTSLRILNLNGNSLSGR 505
PLN03150 PLN03150
hypothetical protein; Provisional
 232-305 5.30e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 53.28  E-value: 5.30e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063704822 232 LQELQNlINLevlglAQNHVDGPIPIEvFCKLKNLRDLDLKGNHFVGQIPLCLGSLKKLRVLDLSSNQLSGDLP 305
Cdd:PLN03150  441 LRHLQS-INL-----SGNSIRGNIPPS-LGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
PLN03150 PLN03150
hypothetical protein; Provisional
 462-571 5.67e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 53.28  E-value: 5.67e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 462 LNGSNNGFQGYFPTSIGEMKNISFLDLSYNNFSGKLPRSFvtgcvsimflklshnkfsgrflpreTNFPSLDVLRMDNNL 541
Cdd:PLN03150  423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSL-------------------------GSITSLEVLDLSYNS 477

                          90       100       110
                  ....*....|....*....|....*....|
gi 1063704822 542 FTGNIGGGLSNSTMLRILDMSNNGLSGAIP 571
Cdd:PLN03150  478 FNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
361-646 6.08e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.16  E-value: 6.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 361 PNFQLSVVVLRFCsLEKipsfllYQKKLRLVDLSSNNLSGNIP----TWLLTNN-----PE-----LEVLQLQNNSFTIF 426
Cdd:PRK15370  163 ANREEAVQRMRDC-LKN------NKTELRLKILGLTTIPACIPeqitTLILDNNelkslPEnlqgnIKTLYANSNQLTSI 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 427 PiPTMVHNLQIFDFSANNIGKFPDKMDHALPNLVRlngSNNGFQGyFPTSIGEmkNISFLDLSYNNFSGkLPRSFVTGcv 506
Cdd:PRK15370  236 P-ATLPDTIQEMELSINRITELPERLPSALQSLDL---FHNKISC-LPENLPE--ELRYLSVYDNSIRT-LPAHLPSG-- 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 507 sIMFLKLSHNKFSgrFLPrETNFPSLDVLRMDNNLFTgniggGLSNS--TMLRILDMSNNGLSgAIPRWLfeFPYLDYVL 584
Cdd:PRK15370  306 -ITHLNVQSNSLT--ALP-ETLPPGLKTLEAGENALT-----SLPASlpPELQVLDVSKNQIT-VLPETL--PPTITTLD 373

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063704822 585 ISNNFLEgTIPPSLLGMpfLSFLDLSGNQFSgALPSHVDSELGiymflhnnnfTGPIPDTLL 646
Cdd:PRK15370  374 VSRNALT-NLPENLPAA--LQIMQASRNNLV-RLPESLPHFRG----------EGPQPTRII 421
PLN03150 PLN03150
hypothetical protein; Provisional
 652-718 7.09e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.90  E-value: 7.09e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063704822 652 LDLRNNKLSGSIP----QFDDTQSINillLKGNNLTGSIPRELCDLSNVRLLDLSDNKLNGVIPSCLSNLS 718
Cdd:PLN03150  423 LGLDNQGLRGFIPndisKLRHLQSIN---LSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLT 490
PLN03150 PLN03150
hypothetical protein; Provisional
 579-736 1.11e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.13  E-value: 1.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 579 YLDYVLISNNFLEGTIPPSLLGMPFLSFLDLSGNQFSGALPSHVdselgiymflhnnnftGPIPdtllkSVQILDLRNNK 658
Cdd:PLN03150  419 FIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSL----------------GSIT-----SLEVLDLSYNS 477

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 659 LSGSIPQ-FDDTQSINILLLKGNNLTGSIPRELcdlsNVRLL-----DLSDNK-LNGV--IPSCLSNLSFGrlQEDAMAL 729
Cdd:PLN03150  478 FNGSIPEsLGQLTSLRILNLNGNSLSGRVPAAL----GGRLLhrasfNFTDNAgLCGIpgLRACGPHLSVG--AKIGIAF 551


                  ....*..
gi 1063704822 730 NIPPSFL 736
Cdd:PLN03150  552 GVSVAFL 558
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 184-301 1.27e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.17  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 184 IKGLKDLTNLELLDLRANKLNgSMQELIHLKKLKALDLSSNKFSssmELQELQNLINLEVLGLAQNHVDGPIPIE----- 258
Cdd:cd21340    39 IENLEFLTNLTHLYLQNNQIE-KIENLENLVNLKKLYLGGNRIS---VVEGLENLTNLEELHIENQRLPPGEKLTfdprs 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1063704822 259 VFCKLKNLRDLDLKGNHFvgQIPLCLGSLKKLRVLDLSSNQLS 301
Cdd:cd21340   115 LAALSNSLRVLNISGNNI--DSLEPLAPLRNLEQLDASNNQIS 155
PLN03150 PLN03150
hypothetical protein; Provisional
 106-205 1.39e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 48.66  E-value: 1.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 106 LHPFEEVRSLNLSTEGYNEFNGFFDDVEGYR-----SLSGLRNLKIMDLSTNYFNYSTFPFLNAATSLTTLILTYNEMDG 180
Cdd:PLN03150  401 QHPWSGADCQFDSTKGKWFIDGLGLDNQGLRgfipnDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNG 480

                          90       100
                  ....*....|....*....|....*
gi 1063704822 181 PFPiKGLKDLTNLELLDLRANKLNG 205
Cdd:PLN03150  481 SIP-ESLGQLTSLRILNLNGNSLSG 504
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 162-301 2.44e-05

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 47.48  E-value: 2.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 162 LNAATSLTTLILTYNEMD---GPFPIKGLKDLTNLELLDLRANKLN--GSM---QELIHLKKLKALDLSSNKFSSS-MEL 232
Cdd:COG5238   204 LTQNTTVTTLWLKRNPIGdegAEILAEALKGNKSLTTLDLSNNQIGdeGVIalaEALKNNTTVETLYLSGNQIGAEgAIA 283

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063704822 233 --QELQNLINLEVLGLAQNHVDGPIPI---EVFCKLKNLRDLDLKGNHF--VGQIPL--CLGSLKKLRVLDLSSNQLS 301
Cdd:COG5238   284 laKALQGNTTLTSLDLSVNRIGDEGAIalaEGLQGNKTLHTLNLAYNGIgaQGAIALakALQENTTLHSLDLSDNQIG 361
PLN03150 PLN03150
hypothetical protein; Provisional
 213-287 2.88e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.50  E-value: 2.88e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063704822 213 LKKLKALDLSSNKFSSSMELQeLQNLINLEVLGLAQNHVDGPIPiEVFCKLKNLRDLDLKGNHFVGQIPLCLGSL 287
Cdd:PLN03150  441 LRHLQSINLSGNSIRGNIPPS-LGSITSLEVLDLSYNSFNGSIP-ESLGQLTSLRILNLNGNSLSGRVPAALGGR 513
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 35-79 4.59e-05

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 41.13  E-value: 4.59e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1063704822  35 EREALLELKKYLmsrsreSGLDYVLPTWTNDTkSDCCQWDGIKCN 79
Cdd:pfam08263   4 DGQALLAFKSSL------NDPPGALSSWNSSS-SDPCSWTGVTCD 41
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 184-341 4.64e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 45.55  E-value: 4.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 184 IKGLKDLTNLELLDLRANKLNgSMQELIHLKKLKALDLSSNKFSssmELQELQNLINLEVLGLAQNHvdgpipIEVFC-- 261
Cdd:cd21340    17 IDNLSLCKNLKVLYLYDNKIT-KIENLEFLTNLTHLYLQNNQIE---KIENLENLVNLKKLYLGGNR------ISVVEgl 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 262 -KLKNLRDLDLKGNH-FVGQI----PLCLGSLKK-LRVLDLSSNQLSgDLpSSFSSLESLEYLSLSDNNFDG----SFSL 330
Cdd:cd21340    87 eNLTNLEELHIENQRlPPGEKltfdPRSLAALSNsLRVLNISGNNID-SL-EPLAPLRNLEQLDASNNQISDleelLDLL 164

                         170
                  ....*....|.
gi 1063704822 331 NPLTNLTNLKL 341
Cdd:cd21340   165 SSWPSLRELDL 175
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 257-494 1.72e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 44.65  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 257 IEVFCKLKNLRDLDLKGNHF----VGQIPLCLGSLKKLRVLDLSSNQLSGD------LPSSFSSLESLEYLSLSDNNF-- 324
Cdd:cd00116    16 TELLPKLLCLQVLRLEGNTLgeeaAKALASALRPQPSLKELCLSLNETGRIprglqsLLQGLTKGCGLQELDLSDNALgp 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 325 DGSFSLNPLTNLTNLKLFKLSSRSHTIQ---VKMESTWQPNFQLSVVVLRFCSLEKIPSF-----LLYQKKLRLVDLSSN 396
Cdd:cd00116    96 DGCGVLESLLRSSSLQELKLNNNGLGDRglrLLAKGLKDLPPALEKLVLGRNRLEGASCEalakaLRANRDLKELNLANN 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 397 NLSGNIPTWL---LTNNPELEVLQLQNNSFT------IFPIPTMVHNLQIFDFSANNIG-----KFPDKMDHALPNLVRL 462
Cdd:cd00116   176 GIGDAGIRALaegLKANCNLEVLDLNNNGLTdegasaLAETLASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTL 255

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1063704822 463 NGSNN-----GFQGyFPTSIGEMKNISFLDLSYNNFS 494
Cdd:cd00116   256 SLSCNditddGAKD-LAEVLAEKESLLELDLRGNKFG 291
LRR_8 pfam13855
Leucine rich repeat;
648-706 2.21e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 2.21e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063704822 648 SVQILDLRNNKLSgSIPQ--FDDTQSINILLLKGNNLTGSIPRELCDLSNVRLLDLSDNKL 706
Cdd:pfam13855   2 NLRSLDLSNNRLT-SLDDgaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 138-303 2.76e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.40  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 138 LSGLRNLKIMDLSTNYFNYS----TFPFLNAATSLTTLILTYNEMDGPFPI---KGLKDLTNLELLDLRANKLNGS---- 206
Cdd:COG5238   232 LKGNKSLTTLDLSNNQIGDEgviaLAEALKNNTTVETLYLSGNQIGAEGAIalaKALQGNTTLTSLDLSVNRIGDEgaia 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 207 -MQELIHLKKLKALDLSSNKFSSS-MEL--QELQNLINLEVLGLAQNHVdGPIPIEVFCKL----KNLRDLDLKGN--HF 276
Cdd:COG5238   312 lAEGLQGNKTLHTLNLAYNGIGAQgAIAlaKALQENTTLHSLDLSDNQI-GDEGAIALAKYlegnTTLRELNLGKNniGK 390

                         170       180
                  ....*....|....*....|....*...
gi 1063704822 277 VGQIPLCLGSLK-KLRVLDLSSNQLSGD 303
Cdd:COG5238   391 QGAEALIDALQTnRLHTLILDGNLIGAE 418
LRR_8 pfam13855
Leucine rich repeat;
240-300 5.85e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.66  E-value: 5.85e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063704822 240 NLEVLGLAQNHVDGpIPIEVFCKLKNLRDLDLKGNHFVGQIPLCLGSLKKLRVLDLSSNQL 300
Cdd:pfam13855   2 NLRSLDLSNNRLTS-LDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 433-500 1.02e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.50  E-value: 1.02e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063704822 433 HNLQIFDFSANNI-GKFPDKMDhALPNLVRLNGSNNGFQGYFPTSIGEMKNISFLDLSYNNFSGKLPRS 500
Cdd:PLN03150  442 RHLQSINLSGNSIrGNIPPSLG-SITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAA 509
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 138-268 1.21e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.31  E-value: 1.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 138 LSGLRNLKIMDLSTNYFnySTFPFLNAATSLTTLILTYNEMDG-------PFPIKGLkdLTNLELLDLRANKLnGSMQEL 210
Cdd:cd21340    64 LENLVNLKKLYLGGNRI--SVVEGLENLTNLEELHIENQRLPPgekltfdPRSLAAL--SNSLRVLNISGNNI-DSLEPL 138

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063704822 211 IHLKKLKALDLSSNKFSSSMELQE-LQNLINLEVLGLAQNHVdgpipievfCKLKNLRD 268
Cdd:cd21340   139 APLRNLEQLDASNNQISDLEELLDlLSSWPSLRELDLTGNPV---------CKKPKYRD 188
PLN03150 PLN03150
hypothetical protein; Provisional
 269-341 2.03e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.73  E-value: 2.03e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063704822 269 LDLKGNHFVGQIPLCLGSLKKLRVLDLSSNQLSGDLPSSFSSLESLEYLSLSDNNFDGSF--SLNPLTNLTNLKL 341
Cdd:PLN03150  423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIpeSLGQLTSLRILNL 497
LRR_8 pfam13855
Leucine rich repeat;
166-226 2.21e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 2.21e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063704822 166 TSLTTLILTYNEMDGpFPIKGLKDLTNLELLDLRANKLNG-SMQELIHLKKLKALDLSSNKF 226
Cdd:pfam13855   1 PNLRSLDLSNNRLTS-LDDGAFKGLSNLKVLDLSNNLLTTlSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 206-345 3.08e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.77  E-value: 3.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 206 SMQELIHLKKLKALDLSSNKFSSsmeLQELQNLINLEVLGLAQNHVDgpiPIEVFCKLKNLRDLDLKGNHfvgqipLC-- 283
Cdd:cd21340    16 KIDNLSLCKNLKVLYLYDNKITK---IENLEFLTNLTHLYLQNNQIE---KIENLENLVNLKKLYLGGNR------ISvv 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 284 --LGSLKKLRVLDLSSNQLSGDLPSSFSSLESL------EYLSLSDNNFDgsfSLNPLTNLTNLKLFKLS 345
Cdd:cd21340    84 egLENLTNLEELHIENQRLPPGEKLTFDPRSLAalsnslRVLNISGNNID---SLEPLAPLRNLEQLDAS 150
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 432-682 3.79e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 40.42  E-value: 3.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 432 VHNLQIFDFSANNIG----KFPDKMDHALPNLVRLNGSNN--GFQGYFPTSIGEM----KNISFLDLSYNNFSGKLPRSF 501
Cdd:cd00116    22 LLCLQVLRLEGNTLGeeaaKALASALRPQPSLKELCLSLNetGRIPRGLQSLLQGltkgCGLQELDLSDNALGPDGCGVL 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 502 --VTGCVSIMFLKLSHNKFSGRFLPR-----ETNFPSLDVLRMDNNLFTGN----IGGGLSNSTMLRILDMSNNGLSGAI 570
Cdd:cd00116   102 esLLRSSSLQELKLNNNGLGDRGLRLlakglKDLPPALEKLVLGRNRLEGAsceaLAKALRANRDLKELNLANNGIGDAG 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 571 PRWLFE----FPYLDYVLISNNFLE----GTIPPSLLGMPFLSFLDLSGNQFSGALPSHVDSELGIY------MFLHNNN 636
Cdd:cd00116   182 IRALAEglkaNCNLEVLDLNNNGLTdegaSALAETLASLKSLEVLNLGDNNLTDAGAAALASALLSPnislltLSLSCND 261

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063704822 637 FT--------GPIPDTllKSVQILDLRNNKLSgsipQFDDTQSINILLLKGNNL 682
Cdd:cd00116   262 ITddgakdlaEVLAEK--ESLLELDLRGNKFG----EEGAQLLAESLLEPGNEL 309
LRR_8 pfam13855
Leucine rich repeat;
556-614 8.11e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 8.11e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063704822 556 LRILDMSNNGLSGAIPRWLFEFPYLDYVLISNNFLEGTIPPSLLGMPFLSFLDLSGNQF 614
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 104-300 8.86e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 39.26  E-value: 8.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 104 SLLHPFEEVRSLNLsteGYNEFNGffddvEGYRSLSGL----RNLKIMDLSTNYFNYSTFPFLnaatslttliltynemd 179
Cdd:cd00116   131 GLKDLPPALEKLVL---GRNRLEG-----ASCEALAKAlranRDLKELNLANNGIGDAGIRAL----------------- 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 180 gpfpIKGLKDLTNLELLDLRANKLN----GSMQELI-HLKKLKALDLSSNKFSS----SMELQELQNLINLEVLGLAQNH 250
Cdd:cd00116   186 ----AEGLKANCNLEVLDLNNNGLTdegaSALAETLaSLKSLEVLNLGDNNLTDagaaALASALLSPNISLLTLSLSCND 261

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063704822 251 V--DGPIP-IEVFCKLKNLRDLDLKGNHF-------VGQIPLCLGSlkKLRVLDLSSNQL 300
Cdd:cd00116   262 ItdDGAKDlAEVLAEKESLLELDLRGNKFgeegaqlLAESLLEPGN--ELESLWVKDDSF 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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