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Conserved domains on  [gi|1063705259|ref|NP_001324955|]
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protein FLC EXPRESSOR [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 31-218 1.03e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259   31 RNRARSVILEDRiaiqhREIQSLLNDNQRLAVAHIGLKDQLNVAKRELERLLETAVKVKAEGEAKVREVyqNALRMEAEA 110
Cdd:TIGR02168  665 SAKTNSSILERR-----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI--SALRKDLAR 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259  111 rvidgLGAELGQVRSDVQRLGSDRQELATELAMFDDEMAKAKPNSDRAIEV-----------KLEIEILRGEIRKGRAAL 179
Cdd:TIGR02168  738 -----LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEieeleaqieqlKEELKALREALDELRAEL 812

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1063705259  180 ELEKKTRASNLHHERGMEKTIDHLNREIVKLEEELVDLE 218
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 31-218 1.03e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259   31 RNRARSVILEDRiaiqhREIQSLLNDNQRLAVAHIGLKDQLNVAKRELERLLETAVKVKAEGEAKVREVyqNALRMEAEA 110
Cdd:TIGR02168  665 SAKTNSSILERR-----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI--SALRKDLAR 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259  111 rvidgLGAELGQVRSDVQRLGSDRQELATELAMFDDEMAKAKPNSDRAIEV-----------KLEIEILRGEIRKGRAAL 179
Cdd:TIGR02168  738 -----LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEieeleaqieqlKEELKALREALDELRAEL 812

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1063705259  180 ELEKKTRASNLHHERGMEKTIDHLNREIVKLEEELVDLE 218
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 101-218 4.69e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 38.18  E-value: 4.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259  101 QNALRMeaeaRVIDGLGAELGQVRSDV---QRLGSDR-QELATELAMFDDEMAKAKPNSDRAIE----VKLEIEILRGEI 172
Cdd:pfam15921  311 QNSMYM----RQLSDLESTVSQLRSELreaKRMYEDKiEELEKQLVLANSELTEARTERDQFSQesgnLDDQLQKLLADL 386

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1063705259  173 RKGRAALELEKKTRASNLHHERGMEKTIDHLNREIVKLEEELVDLE 218
Cdd:pfam15921  387 HKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLE 432
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 31-218 1.03e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259   31 RNRARSVILEDRiaiqhREIQSLLNDNQRLAVAHIGLKDQLNVAKRELERLLETAVKVKAEGEAKVREVyqNALRMEAEA 110
Cdd:TIGR02168  665 SAKTNSSILERR-----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI--SALRKDLAR 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259  111 rvidgLGAELGQVRSDVQRLGSDRQELATELAMFDDEMAKAKPNSDRAIEV-----------KLEIEILRGEIRKGRAAL 179
Cdd:TIGR02168  738 -----LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEieeleaqieqlKEELKALREALDELRAEL 812

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1063705259  180 ELEKKTRASNLHHERGMEKTIDHLNREIVKLEEELVDLE 218
Cdd:TIGR02168  813 TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 28-220 5.80e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 5.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259   28 ESDRNRARSVILEDRIAIQHREIQSLLNDNQRLAVAHIGLKDQLNVAKRELERLLETAVKVKAEGEAKVREVYQNALRME 107
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259  108 AEARVIDGLGAELGQVRSDVQRLGSDRQELATELAMFDDEMAKAkpnSDRAIEVKLEIEILRGEIRKGRAALELEKKTRA 187
Cdd:TIGR02168  800 ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL---EEQIEELSEDIESLAAEIEELEELIEELESELE 876

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1063705259  188 SNLHHERGMEKTIDHLNREIVKLEEELVDLETK 220
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESK 909
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 20-219 4.51e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 38.51  E-value: 4.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259   20 RLLESQLIESDRNRARSVILEDRIAIQH----REIQSLLNDNQRLAVAHIGLKDQLNVAKRELERLLETAVKVKAEGEAK 95
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIeeleREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDY 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259   96 VREvyqnalrmeaearvIDGLGAELGQVRSDVQRLGSDRQELATELAMFDDEMAKAKpnsDRAIEVKLEIEILRGEIRKG 175
Cdd:TIGR02169  391 REK--------------LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE---AKINELEEEKEDKALEIKKQ 453

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1063705259  176 RAALELEKKTRASNLHHERGMEKTIDHLNREIVKLEEELVDLET 219
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEA 497
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 101-218 4.69e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 38.18  E-value: 4.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705259  101 QNALRMeaeaRVIDGLGAELGQVRSDV---QRLGSDR-QELATELAMFDDEMAKAKPNSDRAIE----VKLEIEILRGEI 172
Cdd:pfam15921  311 QNSMYM----RQLSDLESTVSQLRSELreaKRMYEDKiEELEKQLVLANSELTEARTERDQFSQesgnLDDQLQKLLADL 386

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1063705259  173 RKGRAALELEKKTRASNLHHERGMEKTIDHLNREIVKLEEELVDLE 218
Cdd:pfam15921  387 HKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLE 432
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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