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Conserved domains on  [gi|1063703794|ref|NP_001324683|]
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myosin heavy chain-like protein [Arabidopsis thaliana]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
77-430 2.46e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 2.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   77 LQEELAEAYR-VKAQLADLHAGEVAKNL-EAEKQVRFFQGSVAAAFSERDKsvmeaekAEENAEMMSQKLSEIEMRLEEL 154
Cdd:TIGR02168  207 RQAEKAERYKeLKAELRELELALLVLRLeELREELEELQEELKEAEEELEE-------LTAELQELEEKLEELRLEVSEL 279
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  155 SSDCLVQKRLNDTLQADLAKLEEQtrtyagviEKFYDIRKASLCESLEMsLHEKCASLLDDPIEswtfndpsTSDYVAAL 234
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQ--------KQILRERLANLERQLEE-LEAQLEELESKLDE--------LAEELAEL 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  235 EGELGKVKNTVDNLQSKLRVGLEIENHLKKRVRALEKknivadglivngitdirhHHSQLRAYIIALLNEEGLYIKSISK 314
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELEELESRLEELEE------------------QLETLRSKVAQLELQIASLNNEIER 404
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  315 NVEEKLKL-HSSEVQNVVPPQHDLKPDESECRDVHMTTVVESCQVTKLAEASIAKIMAESRGDASEAFAQAlqekvgALL 393
Cdd:TIGR02168  405 LEARLERLeDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ------ALD 478
                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1063703794  394 LLSQQEERHLHEENVNAALQQKVDELQRNILQVTNEK 430
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2-108 5.34e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 5.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794    2 DLNLDENENLKARIKQLEHERNELQKDIEQlcmqqggpsiLGVAARMHFQRTASLEQEIESLKLKLAACTREKHNLQEEL 81
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDE----------LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750
                           90       100
                   ....*....|....*....|....*..
gi 1063703794   82 AEAyRVKAQLADLHAGEVAKNLEAEKQ 108
Cdd:COG4913    751 LEE-RFAAALGDAVERELRENLEERID 776
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
77-430 2.46e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 2.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   77 LQEELAEAYR-VKAQLADLHAGEVAKNL-EAEKQVRFFQGSVAAAFSERDKsvmeaekAEENAEMMSQKLSEIEMRLEEL 154
Cdd:TIGR02168  207 RQAEKAERYKeLKAELRELELALLVLRLeELREELEELQEELKEAEEELEE-------LTAELQELEEKLEELRLEVSEL 279
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  155 SSDCLVQKRLNDTLQADLAKLEEQtrtyagviEKFYDIRKASLCESLEMsLHEKCASLLDDPIEswtfndpsTSDYVAAL 234
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQ--------KQILRERLANLERQLEE-LEAQLEELESKLDE--------LAEELAEL 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  235 EGELGKVKNTVDNLQSKLRVGLEIENHLKKRVRALEKknivadglivngitdirhHHSQLRAYIIALLNEEGLYIKSISK 314
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELEELESRLEELEE------------------QLETLRSKVAQLELQIASLNNEIER 404
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  315 NVEEKLKL-HSSEVQNVVPPQHDLKPDESECRDVHMTTVVESCQVTKLAEASIAKIMAESRGDASEAFAQAlqekvgALL 393
Cdd:TIGR02168  405 LEARLERLeDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ------ALD 478
                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1063703794  394 LLSQQEERHLHEENVNAALQQKVDELQRNILQVTNEK 430
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
7-449 2.53e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 2.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   7 ENENLKARIKQLEHERNELQKDIEQLCMQQ-GGPSILGVAARM---HFQR---TASLEQEIESLKLKLAACTREKHNLQE 79
Cdd:PRK02224  200 EEKDLHERLNGLESELAELDEEIERYEEQReQARETRDEADEVleeHEERreeLETLEAEIEDLRETIAETEREREELAE 279
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  80 ELAEAYRVKAQLADLHAGEVAKnleaekqvrffqgsvaAAFSERDKSVmeaekaeenaemMSQKLSEIEMRLEELSSDcL 159
Cdd:PRK02224  280 EVRDLRERLEELEEERDDLLAE----------------AGLDDADAEA------------VEARREELEDRDEELRDR-L 330
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 160 VQKRLN--------DTLQADLAKLEEQT---RTYAGVIEKFYDIRKASLcESLEMSLHEkcaslLDDPIESW--TFNDPS 226
Cdd:PRK02224  331 EECRVAaqahneeaESLREDADDLEERAeelREEAAELESELEEAREAV-EDRREEIEE-----LEEEIEELreRFGDAP 404
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 227 T-----SDYVAALEGELGKVKNTVDNLQSKLRvglEIENHLKKRVRALEKKNI------VADGLIVNGITDIRHHHSQLR 295
Cdd:PRK02224  405 VdlgnaEDFLEELREERDELREREAELEATLR---TARERVEEAEALLEAGKCpecgqpVEGSPHVETIEEDRERVEELE 481
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 296 AYIIALLNEeglyIKSISKNVEEKLKLHSSEVQnvVPPQHDLKPDESECRDVHMTTVVEscQVTKLAEASIAKIMAESRG 375
Cdd:PRK02224  482 AELEDLEEE----VEEVEERLERAEDLVEAEDR--IERLEERREDLEELIAERRETIEE--KRERAEELRERAAELEAEA 553
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063703794 376 DASEAFAQALQEKVgallllsqQEERhlheeNVNAALQQKVDELQRNILQVtnEKVRTLM-ELAQLRQEYQSLRE 449
Cdd:PRK02224  554 EEKREAAAEAEEEA--------EEAR-----EEVAELNSKLAELKERIESL--ERIRTLLaAIADAEDEIERLRE 613
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
7-449 8.75e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 8.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   7 ENENLKARIKQLEHERNELQKDIEQLCmqqggpsilgvaarmhfQRTASLEQEIESLKLKLAACTREKHNLQEELAEAYR 86
Cdd:COG1196   289 EEYELLAELARLEQDIARLEERRRELE-----------------ERLEELEEELAELEEELEELEEELEELEEELEEAEE 351
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  87 VKAQLADLHAGEVAKNLEAEKQVRFFQGSVAAA----FSERDKSVMEAEKAEENAEMMSQKLSEIEMRLEELSSDCLVQK 162
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELaeelLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 163 RLNDTLQADLAKLEEQTRTYAGVIEKFYDIRKASLCESLEMSLHEKCASLLDDPIESWTFNDPSTSDYVAALEGELGKVK 242
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 243 NTVDN-LQSKLRVGLEIENHLKKRVRALEkkNIVADGLIVNGITDIRhhhSQLRAYIIALLNE-----EGLYIKSISKNV 316
Cdd:COG1196   512 AALLLaGLRGLAGAVAVLIGVEAAYEAAL--EAALAAALQNIVVEDD---EVAAAAIEYLKAAkagraTFLPLDKIRARA 586
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 317 EEKLKLHSSEVQNVVPPQHDLKPDESECRDVHMTTVVESCQVTKLAEASIaKIMAESRGDASEAFAQALQEKVGALLLLS 396
Cdd:COG1196   587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL-RRAVTLAGRLREVTLEGEGGSAGGSLTGG 665
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063703794 397 QQEERHLHEENVNAALQQKVDELQRNILQVTNEKVRTLMELAQLRQEYQSLRE 449
Cdd:COG1196   666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2-108 5.34e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 5.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794    2 DLNLDENENLKARIKQLEHERNELQKDIEQlcmqqggpsiLGVAARMHFQRTASLEQEIESLKLKLAACTREKHNLQEEL 81
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDE----------LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750
                           90       100
                   ....*....|....*....|....*..
gi 1063703794   82 AEAyRVKAQLADLHAGEVAKNLEAEKQ 108
Cdd:COG4913    751 LEE-RFAAALGDAVERELRENLEERID 776
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
77-430 2.46e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 2.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   77 LQEELAEAYR-VKAQLADLHAGEVAKNL-EAEKQVRFFQGSVAAAFSERDKsvmeaekAEENAEMMSQKLSEIEMRLEEL 154
Cdd:TIGR02168  207 RQAEKAERYKeLKAELRELELALLVLRLeELREELEELQEELKEAEEELEE-------LTAELQELEEKLEELRLEVSEL 279
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  155 SSDCLVQKRLNDTLQADLAKLEEQtrtyagviEKFYDIRKASLCESLEMsLHEKCASLLDDPIEswtfndpsTSDYVAAL 234
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQ--------KQILRERLANLERQLEE-LEAQLEELESKLDE--------LAEELAEL 342
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  235 EGELGKVKNTVDNLQSKLRVGLEIENHLKKRVRALEKknivadglivngitdirhHHSQLRAYIIALLNEEGLYIKSISK 314
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELEELESRLEELEE------------------QLETLRSKVAQLELQIASLNNEIER 404
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  315 NVEEKLKL-HSSEVQNVVPPQHDLKPDESECRDVHMTTVVESCQVTKLAEASIAKIMAESRGDASEAFAQAlqekvgALL 393
Cdd:TIGR02168  405 LEARLERLeDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ------ALD 478
                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1063703794  394 LLSQQEERHLHEENVNAALQQKVDELQRNILQVTNEK 430
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
7-449 2.53e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 2.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   7 ENENLKARIKQLEHERNELQKDIEQLCMQQ-GGPSILGVAARM---HFQR---TASLEQEIESLKLKLAACTREKHNLQE 79
Cdd:PRK02224  200 EEKDLHERLNGLESELAELDEEIERYEEQReQARETRDEADEVleeHEERreeLETLEAEIEDLRETIAETEREREELAE 279
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  80 ELAEAYRVKAQLADLHAGEVAKnleaekqvrffqgsvaAAFSERDKSVmeaekaeenaemMSQKLSEIEMRLEELSSDcL 159
Cdd:PRK02224  280 EVRDLRERLEELEEERDDLLAE----------------AGLDDADAEA------------VEARREELEDRDEELRDR-L 330
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 160 VQKRLN--------DTLQADLAKLEEQT---RTYAGVIEKFYDIRKASLcESLEMSLHEkcaslLDDPIESW--TFNDPS 226
Cdd:PRK02224  331 EECRVAaqahneeaESLREDADDLEERAeelREEAAELESELEEAREAV-EDRREEIEE-----LEEEIEELreRFGDAP 404
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 227 T-----SDYVAALEGELGKVKNTVDNLQSKLRvglEIENHLKKRVRALEKKNI------VADGLIVNGITDIRHHHSQLR 295
Cdd:PRK02224  405 VdlgnaEDFLEELREERDELREREAELEATLR---TARERVEEAEALLEAGKCpecgqpVEGSPHVETIEEDRERVEELE 481
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 296 AYIIALLNEeglyIKSISKNVEEKLKLHSSEVQnvVPPQHDLKPDESECRDVHMTTVVEscQVTKLAEASIAKIMAESRG 375
Cdd:PRK02224  482 AELEDLEEE----VEEVEERLERAEDLVEAEDR--IERLEERREDLEELIAERRETIEE--KRERAEELRERAAELEAEA 553
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063703794 376 DASEAFAQALQEKVgallllsqQEERhlheeNVNAALQQKVDELQRNILQVtnEKVRTLM-ELAQLRQEYQSLRE 449
Cdd:PRK02224  554 EEKREAAAEAEEEA--------EEAR-----EEVAELNSKLAELKERIESL--ERIRTLLaAIADAEDEIERLRE 613
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
7-449 8.75e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 8.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   7 ENENLKARIKQLEHERNELQKDIEQLCmqqggpsilgvaarmhfQRTASLEQEIESLKLKLAACTREKHNLQEELAEAYR 86
Cdd:COG1196   289 EEYELLAELARLEQDIARLEERRRELE-----------------ERLEELEEELAELEEELEELEEELEELEEELEEAEE 351
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  87 VKAQLADLHAGEVAKNLEAEKQVRFFQGSVAAA----FSERDKSVMEAEKAEENAEMMSQKLSEIEMRLEELSSDCLVQK 162
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELaeelLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 163 RLNDTLQADLAKLEEQTRTYAGVIEKFYDIRKASLCESLEMSLHEKCASLLDDPIESWTFNDPSTSDYVAALEGELGKVK 242
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 243 NTVDN-LQSKLRVGLEIENHLKKRVRALEkkNIVADGLIVNGITDIRhhhSQLRAYIIALLNE-----EGLYIKSISKNV 316
Cdd:COG1196   512 AALLLaGLRGLAGAVAVLIGVEAAYEAAL--EAALAAALQNIVVEDD---EVAAAAIEYLKAAkagraTFLPLDKIRARA 586
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 317 EEKLKLHSSEVQNVVPPQHDLKPDESECRDVHMTTVVESCQVTKLAEASIaKIMAESRGDASEAFAQALQEKVGALLLLS 396
Cdd:COG1196   587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL-RRAVTLAGRLREVTLEGEGGSAGGSLTGG 665
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063703794 397 QQEERHLHEENVNAALQQKVDELQRNILQVTNEKVRTLMELAQLRQEYQSLRE 449
Cdd:COG1196   666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
7-181 1.63e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   7 ENENLKARIKQLEHERNELQKDIEQLcmqqggpsilGVAARMHFQRTASLEQEIESLKLKLAACTREKHNLQEELAEAYR 86
Cdd:COG1196   261 ELAELEAELEELRLELEELELELEEA----------QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  87 VKAQLADLHAGEVAKNLEAEKQVRFFQGSVAAAFSERDKSVMEAEKAEENAEMMSQKLSEIEMRLEELSSDCLVQKRLND 166
Cdd:COG1196   331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410
                         170
                  ....*....|....*
gi 1063703794 167 TLQADLAKLEEQTRT 181
Cdd:COG1196   411 ALLERLERLEEELEE 425
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
2-443 3.90e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.31  E-value: 3.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   2 DLNLDENENLKARIKQLEHERNELQKDIEQLcmqqggpsilgvAARMHFQRT--ASLEQEIESLKLKLAACTREKHNLQE 79
Cdd:COG1196   305 ARLEERRRELEERLEELEEELAELEEELEEL------------EEELEELEEelEEAEEELEEAEAELAEAEEALLEAEA 372
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  80 ELAEAYRVKAQLADLHAGEVAKNLEAEKQVRFFQGSVAAAFSERDKSVMEAEKAEENAEMMSQKLSEIEMRLEELSSDcl 159
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE-- 450
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 160 vQKRLNDTLQADLAKLEEQTRTYAGVIEKFYDIRKASLCESLEMSLHEKCASLLDDPIESWTFNDPSTSD---------- 229
Cdd:COG1196   451 -EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavavl 529
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 230 ------YVAALEGELGKVknTVDNLQSKLRVGLEIENHLKKrvRALEKKNIVADGLIVNGITDIRHHHSQLRAYIIALLN 303
Cdd:COG1196   530 igveaaYEAALEAALAAA--LQNIVVEDDEVAAAAIEYLKA--AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 304 EEGLYIKSISKNVEEKLKLHSSEVqnvvppqhdlkpdesecRDVHMTTVVESCQVTKLAEASIAKIMAESRGDASEAFAQ 383
Cdd:COG1196   606 SDLREADARYYVLGDTLLGRTLVA-----------------ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR 668
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794 384 ALQEKVGALLLLSQQEERHLHEENVNAALQQKVDELQRNILQVTNEKVRTLMELAQLRQE 443
Cdd:COG1196   669 ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
6-318 4.46e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.05  E-value: 4.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794    6 DENENLKARIKQLEHERNELQKD---IEQLCMQQggPSILGVAARMHFQRTASLEQ----------EIESLKLKLAACTR 72
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSLQSElrrIENRLDEL--SQELSDASRKIGEIEKEIEQleqeeeklkeRLEELEEDLSSLEQ 751
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   73 EKHNLQEELAEAYRVKAQL-ADLHAGEVAKN-LEAEKQVRFFQGSVAAAfSERDKSVMEaekaeenaemMSQKLSEIEMR 150
Cdd:TIGR02169  752 EIENVKSELKELEARIEELeEDLHKLEEALNdLEARLSHSRIPEIQAEL-SKLEEEVSR----------IEARLREIEQK 820
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  151 LEELSSDCLVQKRLNDTLQADLAKLEEQTRTYAGVIEKFyDIRKASLCESLEmslhEKCASLLDdpieswtfndpstsdy 230
Cdd:TIGR02169  821 LNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL-NGKKEELEEELE----ELEAALRD---------------- 879
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  231 vaaLEGELGKVKNTVDNLQSKLRVgleienhLKKRVRALEKKnivadglivngITDIRHHHSQLRAYIIALLNEEGLYIK 310
Cdd:TIGR02169  880 ---LESRLGDLKKERDELEAQLRE-------LERKIEELEAQ-----------IEKKRKRLSELKAKLEALEEELSEIED 938

                   ....*...
gi 1063703794  311 SISKNVEE 318
Cdd:TIGR02169  939 PKGEDEEI 946
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2-108 5.34e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 5.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794    2 DLNLDENENLKARIKQLEHERNELQKDIEQlcmqqggpsiLGVAARMHFQRTASLEQEIESLKLKLAACTREKHNLQEEL 81
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDE----------LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL 750
                           90       100
                   ....*....|....*....|....*..
gi 1063703794   82 AEAyRVKAQLADLHAGEVAKNLEAEKQ 108
Cdd:COG4913    751 LEE-RFAAALGDAVERELRENLEERID 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
7-181 5.71e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 39.67  E-value: 5.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794    7 ENENLKARIKQLEHERNELQKDIEQLcmqqggpsilGVAARMHFQRTASLEQEIESLKLKLAACTREKHNLQEELAeayR 86
Cdd:TIGR02169  351 RRDKLTEEYAELKEELEDLRAELEEV----------DKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQ---R 417
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   87 VKAQLADLHAGevAKNLEAEKqvrffqgsvaAAFSERDKSVMEAEKAEENAEM-MSQKLSEIEMRLEELSSDC-LVQKRL 164
Cdd:TIGR02169  418 LSEELADLNAA--IAGIEAKI----------NELEEEKEDKALEIKKQEWKLEqLAADLSKYEQELYDLKEEYdRVEKEL 485
                          170
                   ....*....|....*..
gi 1063703794  165 NDtLQADLAKLEEQTRT 181
Cdd:TIGR02169  486 SK-LQRELAEAEAQARA 501
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
9-108 7.10e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 39.29  E-value: 7.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   9 ENLKARIKQLEHERNELQKDIEQLcmqqggpsilgvaarmHFQRTASLEQEIESLKLKLAACTREKHNLQEELAEAYRVK 88
Cdd:COG0542   414 DELERRLEQLEIEKEALKKEQDEA----------------SFERLAELRDELAELEEELEALKARWEAEKELIEEIQELK 477
                          90       100
                  ....*....|....*....|..
gi 1063703794  89 AQLADLHA--GEVAKNLEAEKQ 108
Cdd:COG0542   478 EELEQRYGkiPELEKELAELEE 499
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
6-273 7.57e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.27  E-value: 7.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794    6 DENENLKARIKQLEHERNELQKDIEQLCMQQGGPSILGVAARMHFQRtasLEQEIESLKLKLAactrekhNLQEELAEAY 85
Cdd:TIGR02168  691 EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR---LEAEVEQLEERIA-------QLSKELTELE 760
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794   86 RVKAQLADLHAGEVAKNLEAEKQVRFFQGSVAAAFSERDKSVMEAEKAEENAEMMSQKLSEIEMRLEELSSDCLVQKRLN 165
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063703794  166 DTLQADLAKLEEQTRTYAGVIEKfydirkaslCESLEMSLHEKCASLLDDpieswtfndpstsdyVAALEGELGKVKNTV 245
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEE---------LEELIEELESELEALLNE---------------RASLEEALALLRSEL 896
                          250       260
                   ....*....|....*....|....*...
gi 1063703794  246 DNLQSKLRvglEIENHLKKRVRALEKKN 273
Cdd:TIGR02168  897 EELSEELR---ELESKRSELRRELEELR 921
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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