MATE efflux family protein [Arabidopsis thaliana]
Protein Classification
MATE family efflux transporter( domain architecture ID 10192094)
MATE (multidrug and toxic compound extrusion) family efflux transporter functions in protecting cells against oxidative stress and bile salts and may be part of the SOS system; similar to Arabidopsis thaliana MATE proteins which confer aluminum tolerance
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||
| MATE_DinF_like | cd13136 | DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
50-390 | 2.55e-82 | ||||||
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR). : Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 258.26 E-value: 2.55e-82
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| Name | Accession | Description | Interval | E-value | ||||||
| MATE_DinF_like | cd13136 | DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
50-390 | 2.55e-82 | ||||||
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR). Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 258.26 E-value: 2.55e-82
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| matE | TIGR00797 | putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
50-390 | 1.22e-68 | ||||||
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other] Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 220.19 E-value: 1.22e-68
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| NorM | COG0534 | Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
51-385 | 5.91e-44 | ||||||
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 157.61 E-value: 5.91e-44
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| PRK10367 | PRK10367 | DNA-damage-inducible SOS response protein; Provisional |
162-380 | 3.17e-11 | ||||||
DNA-damage-inducible SOS response protein; Provisional Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 64.37 E-value: 3.17e-11
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| MatE | pfam01554 | MatE; The MatE domain |
54-258 | 3.98e-09 | ||||||
MatE; The MatE domain Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 55.26 E-value: 3.98e-09
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| Name | Accession | Description | Interval | E-value | ||||||
| MATE_DinF_like | cd13136 | DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
50-390 | 2.55e-82 | ||||||
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR). Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 258.26 E-value: 2.55e-82
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| matE | TIGR00797 | putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
50-390 | 1.22e-68 | ||||||
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other] Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 220.19 E-value: 1.22e-68
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| NorM | COG0534 | Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
51-385 | 5.91e-44 | ||||||
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 157.61 E-value: 5.91e-44
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| MATE_NorM_like | cd13137 | Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
54-389 | 9.63e-28 | ||||||
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 113.38 E-value: 9.63e-28
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| MATE_like_1 | cd13140 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
167-381 | 1.42e-25 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 107.23 E-value: 1.42e-25
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| MATE_yoeA_like | cd13138 | Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
166-381 | 2.05e-23 | ||||||
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 101.00 E-value: 2.05e-23
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| MATE_MepA_like | cd13143 | Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
148-384 | 3.44e-21 | ||||||
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump. Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 94.50 E-value: 3.44e-21
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| MATE_like_8 | cd13134 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
167-389 | 5.34e-19 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 88.33 E-value: 5.34e-19
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| MATE_like | cd12082 | Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
167-385 | 6.45e-19 | ||||||
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 87.76 E-value: 6.45e-19
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| MATE_MJ0709_like | cd13147 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
166-363 | 2.51e-16 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 80.28 E-value: 2.51e-16
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| MATE_like_7 | cd13133 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
165-389 | 3.57e-15 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 76.80 E-value: 3.57e-15
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| MATE_like_4 | cd13144 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
167-302 | 3.85e-15 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 76.50 E-value: 3.85e-15
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| MATE_like_2 | cd13149 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
52-303 | 1.49e-14 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 74.65 E-value: 1.49e-14
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| MATE_like_12 | cd13142 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
166-385 | 4.63e-14 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 73.38 E-value: 4.63e-14
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| MATE_like_6 | cd13146 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
167-384 | 2.51e-13 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 70.89 E-value: 2.51e-13
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| MATE_NorM_like | cd13131 | Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
54-385 | 5.20e-13 | ||||||
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate. Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 69.84 E-value: 5.20e-13
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| PRK10367 | PRK10367 | DNA-damage-inducible SOS response protein; Provisional |
162-380 | 3.17e-11 | ||||||
DNA-damage-inducible SOS response protein; Provisional Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 64.37 E-value: 3.17e-11
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| MATE_like_14 | cd13139 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
166-364 | 8.81e-10 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 59.93 E-value: 8.81e-10
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| MatE | pfam01554 | MatE; The MatE domain |
54-258 | 3.98e-09 | ||||||
MatE; The MatE domain Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 55.26 E-value: 3.98e-09
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| MATE_like_3 | cd13148 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
170-289 | 5.49e-09 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 57.67 E-value: 5.49e-09
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| MATE_like_5 | cd13145 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
167-380 | 6.41e-09 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 57.22 E-value: 6.41e-09
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| vmrA | PRK09575 | MATE family efflux transporter; |
148-284 | 4.56e-07 | ||||||
MATE family efflux transporter; Pssm-ID: 236576 [Multi-domain] Cd Length: 453 Bit Score: 51.53 E-value: 4.56e-07
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| MurJ | COG0728 | Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope ... |
168-372 | 5.14e-07 | ||||||
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 440492 [Multi-domain] Cd Length: 503 Bit Score: 51.69 E-value: 5.14e-07
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| MATE_NorM_like | cd13137 | Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
170-287 | 8.61e-07 | ||||||
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 50.59 E-value: 8.61e-07
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| MATE_like_9 | cd13135 | Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
52-285 | 4.62e-06 | ||||||
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 48.44 E-value: 4.62e-06
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| MATE_MurJ_like | cd13123 | MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
168-289 | 7.71e-06 | ||||||
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR). Pssm-ID: 240528 [Multi-domain] Cd Length: 420 Bit Score: 47.83 E-value: 7.71e-06
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| MATE_eukaryotic | cd13132 | Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
177-286 | 4.62e-05 | ||||||
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress. Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 45.26 E-value: 4.62e-05
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| murJ_mviN | TIGR01695 | murein biosynthesis integral membrane protein MurJ; This model represents MurJ (previously ... |
212-289 | 2.21e-04 | ||||||
murein biosynthesis integral membrane protein MurJ; This model represents MurJ (previously MviN), a family of integral membrane proteins predicted to have ten or more transmembrane regions. Members have been suggested to act as a lipid II flippase, translocated a precursor of murein. However, it appears FtsW has that activity. Flippase activity for MurJ has not been shown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan] Pssm-ID: 273763 [Multi-domain] Cd Length: 502 Bit Score: 43.08 E-value: 2.21e-04
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| NorM | COG0534 | Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
170-287 | 3.88e-04 | ||||||
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 42.44 E-value: 3.88e-04
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| Polysacc_synt_C | pfam14667 | Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
211-289 | 1.09e-03 | ||||||
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins. Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 39.09 E-value: 1.09e-03
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| PRK10189 | PRK10189 | EmmdR/YeeO family multidrug/toxin efflux MATE transporter; |
160-290 | 1.22e-03 | ||||||
EmmdR/YeeO family multidrug/toxin efflux MATE transporter; Pssm-ID: 182293 [Multi-domain] Cd Length: 478 Bit Score: 40.87 E-value: 1.22e-03
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| RfbX | COG2244 | Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
170-286 | 1.97e-03 | ||||||
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 39.93 E-value: 1.97e-03
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| MurJ | pfam03023 | Lipid II flippase MurJ; Peptidoglycan synthesis (PG) biosynthesis involves the formation of ... |
212-296 | 2.43e-03 | ||||||
Lipid II flippase MurJ; Peptidoglycan synthesis (PG) biosynthesis involves the formation of peptidoglycan precursor lipid II (undecaprenyl-pyrophosphate-linked N-acetyl glucosamine-N-acetyl muramic acid-pentapeptide) on the cytosolic face of the cell membrane. Lipid II is then translocated across the membrane and its glycopeptide moiety becomes incorporated into the growing cell wall mesh. MviN, renamed as MurJ, is a lipid II flippase essential for cell wall peptidoglycan synthesis. MurJ belongs to the MVF (mouse virulence factor) family of MOP superfamily transporters, which also includes the MATE (multidrug and toxic compound extrusion) transporter and eukaryotic OLF (oligosaccharidyl-lipid flippase) families. In addition to the canonical MOP transporter core consisting of 12 transmembrane helices (TMs), MurJ has two additional C-terminal TMs (13 and 14) of unknown function. Structural analysis indicates that the N lobe (TMs 1-6) and C lobe (TMs 7-14) are arranged in an inward-facing N-shape conformation, rather than the outward-facing V-shape conformation observed in all existing MATE transporter structures. Furthermore, a hydrophobic groove is formed by two C-terminal transmembrane helices, which leads into a large central cavity that is mostly cationic. Mutagenesis studies, revealed a solvent-exposed cavity that is essential for function. Mutation of conserved residues (Ser17, Arg18, Arg24, Arg52, and Arg255) at the proximal site failed to complement MurJ function, consistent with the idea that these residues are important for recognizing the diphosphate and/or sugar moieties of lipid II. It has also been suggested that the chloride ion in the central cavity and a zinc ion at the beginning of TM 7 might be functionally important. Pssm-ID: 397249 [Multi-domain] Cd Length: 451 Bit Score: 39.97 E-value: 2.43e-03
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| PRK01766 | PRK01766 | multidrug efflux protein; Reviewed |
170-287 | 5.38e-03 | ||||||
multidrug efflux protein; Reviewed Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 38.64 E-value: 5.38e-03
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