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Conserved domains on  [gi|1063696628|ref|NP_001322207|]
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ILITYHIA [Arabidopsis thaliana]

Protein Classification

IPI1/TEX10 family protein( domain architecture ID 12145868)

IPI1/TEX10 family protein similar to human testis-expressed protein 10 (TEX10) that functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, and Saccharomyces cerevisiae pre-rRNA-processing protein IPI1 that is a component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA; contains a HEAT repeat domain that may function as a scaffold, anchoring and/or adaptor protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HSH155 super family cl26678
U2 snRNP spliceosome subunit [RNA processing and modification];
1932-2597 3.35e-11

U2 snRNP spliceosome subunit [RNA processing and modification];


The actual alignment was detected with superfamily member COG5181:

Pssm-ID: 227508 [Multi-domain]  Cd Length: 975  Bit Score: 69.21  E-value: 3.35e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1932 LKEIMPILMStlissLASPSSERRQVAG------RSLGELVRKLGERVLPLIIPILSkglkDPDVDKRqgvCIGLNEVMA 2005
Cdd:COG5181    205 FNKVLPMLMS-----RELEDQERHLVVKlidrllYGLDDLKVPYVHKILVVVGPLLI----DEDLKRR---CMGREIILN 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2006 SAGRSQLlSFMdqlIPTIRTALCDSALEVRESAGLAFSTLYKSAGLQAMDEIIPTLLEALEDDEMSTTALDGLKQIISVR 2085
Cdd:COG5181    273 LVYRCGL-GFS---VSSMRPDITSKDEYVRNVTGRAVGVVADALGVEELLPFLEALCGSRKSWEARHTGIRIAQQICELL 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2086 TAAVLPH------ILPKLV---HLPLSALNAHALGALAEVAG---------------AGFNTHLGTILPALLSAMGGENK 2141
Cdd:COG5181    349 GRSRLSHlgpllkCISKLLkdrSRFVRIDTANALSYLAELVGpygieqfdevlcplwEGASQHRGKELVSFLKAMGFIIP 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2142 EVQ-ELAQEAAERVVLVI-------DEEGVETLLseLLKGVSDSQASI-------------------RRSSAYLIGY--- 2191
Cdd:COG5181    429 LMSpEYACHDTREHMEIVfrefkspDEEMKKDLL--VVERICDKVGTDtpwklrdqvspeffspfwrRRSAGDRRSYkqv 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2192 FFKSSKLYLIDEAPNMISTLIVMLSDSDSTTVAVSWEALARVIGSVPK-EVLPSYIKLVRDAVSTA------RDKERRKR 2264
Cdd:COG5181    507 VLTTVILAKMGGDPRVSRKILEYYSDEPEPYRKMNAGLVSRIFSRLGRlGFDERLEERLYDSILNAfqeqdtTVGLILPC 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2265 KGGYVVIPGLCLPKSLKPLLPVFLQGLISGSAELREQAAIGLGELIEVTSEQALKEFVIPITGPLIRIIGDRFPWQVKSA 2344
Cdd:COG5181    587 FSTVLVSLEFRGKPHLSMIVSTILKLLRSKPPDVRIRAADLMGSLAKVLKACGETKELAKLGNILYENLGEDYPEVLGSI 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2345 ILATLIILIQRGGMALKPFLPQLQTTFVKCLQDSTRTIRSSAAVALGKLSALS-TRIDP-----LVGDLMTSFQAADSGV 2418
Cdd:COG5181    667 LKAICSIYSVHRFRSMQPPISGILPSLTPILRNKHQKVVANTIALVGTICMNSpEYIGVrewmrICFELVDSLKSWNKEI 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2419 REAILSAMrGVIkhaGKSIGPAvrvRIFDLLKDLMHHEDDQVRISATSMLGVLSQYleAAQLSVLLQEVNDLSaSQNWGA 2498
Cdd:COG5181    747 RRNATETF-GCI---SRAIGPQ---DVLDILLNNLKVQERQQRVCTSVAISIVAEY--CGPFSVLPTLMSDYE-TPEANV 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2499 RHGSVLCISSLLK--HNpstiMTSSLFSSMLNSLKSSLKDekfplRESSTKALGRLLLKQLATDPSNTKVV---IDVLSS 2573
Cdd:COG5181    817 QNGVLKAMCFMFEyiGQ----ASLDYVYSITPLLEDALTD-----RDPVHRQTAMNVIRHLVLNCPGTGDEdaaIHLLNL 887

                          730       740
                   ....*....|....*....|....
gi 1063696628 2574 IVSALHDDSSEVRRRALSSLKAFA 2597
Cdd:COG5181    888 LWPNILEPSPHVIQSFDEGMESFA 911
HEAT COG1413
HEAT repeat [General function prediction only];
1688-1855 1.20e-06

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 50.01  E-value: 1.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1688 VRSVAARAVGSLirgmGEdnfPDLVPWLFETLKSDTSNVeRYGAAQglseviaALGTDYFENILPDLIRHCSHQKASVRD 1767
Cdd:COG1413      1 VRRAAARALGRL----GD---PAAVPALIAALADEDPDV-RAAAAR-------ALGRLGDPRAVPALLEALKDPDPEVRA 65

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1768 GYLtlfkflpRSLGAQFQKylqLVLPAILDGLADENESVRDAALGAghvLVEHHATTSLPLLLPAVEDgifnDNWRIRQS 1847
Cdd:COG1413     66 AAA-------EALGRIGDP---EAVPALIAALKDEDPEVRRAAAEA---LGRLGDPAAVPALLEALKD----PDWEVRRA 128


                   ....*...
gi 1063696628 1848 SVELLGDL 1855
Cdd:COG1413    129 AARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
1503-1609 3.71e-04

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 43.08  E-value: 3.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1503 QLSAYGVKLVLPSLLKGLEDKAWRTKQSSVQLLGAMAfcapqqlsqcLPRVVPKLTEVLTDTHPKVQSAGQLALqqvgSV 1582
Cdd:COG1413      8 ALGRLGDPAAVPALIAALADEDPDVRAAAARALGRLG----------DPRAVPALLEALKDPDPEVRAAAAEAL----GR 73

                           90       100
                   ....*....|....*....|....*..
gi 1063696628 1583 IKNPEIsslVPTLLLALTDPNEYTRHA 1609
Cdd:COG1413     74 IGDPEA---VPALIAALKDEDPEVRRA 97
 
Name Accession Description Interval E-value
HSH155 COG5181
U2 snRNP spliceosome subunit [RNA processing and modification];
1932-2597 3.35e-11

U2 snRNP spliceosome subunit [RNA processing and modification];


Pssm-ID: 227508 [Multi-domain]  Cd Length: 975  Bit Score: 69.21  E-value: 3.35e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1932 LKEIMPILMStlissLASPSSERRQVAG------RSLGELVRKLGERVLPLIIPILSkglkDPDVDKRqgvCIGLNEVMA 2005
Cdd:COG5181    205 FNKVLPMLMS-----RELEDQERHLVVKlidrllYGLDDLKVPYVHKILVVVGPLLI----DEDLKRR---CMGREIILN 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2006 SAGRSQLlSFMdqlIPTIRTALCDSALEVRESAGLAFSTLYKSAGLQAMDEIIPTLLEALEDDEMSTTALDGLKQIISVR 2085
Cdd:COG5181    273 LVYRCGL-GFS---VSSMRPDITSKDEYVRNVTGRAVGVVADALGVEELLPFLEALCGSRKSWEARHTGIRIAQQICELL 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2086 TAAVLPH------ILPKLV---HLPLSALNAHALGALAEVAG---------------AGFNTHLGTILPALLSAMGGENK 2141
Cdd:COG5181    349 GRSRLSHlgpllkCISKLLkdrSRFVRIDTANALSYLAELVGpygieqfdevlcplwEGASQHRGKELVSFLKAMGFIIP 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2142 EVQ-ELAQEAAERVVLVI-------DEEGVETLLseLLKGVSDSQASI-------------------RRSSAYLIGY--- 2191
Cdd:COG5181    429 LMSpEYACHDTREHMEIVfrefkspDEEMKKDLL--VVERICDKVGTDtpwklrdqvspeffspfwrRRSAGDRRSYkqv 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2192 FFKSSKLYLIDEAPNMISTLIVMLSDSDSTTVAVSWEALARVIGSVPK-EVLPSYIKLVRDAVSTA------RDKERRKR 2264
Cdd:COG5181    507 VLTTVILAKMGGDPRVSRKILEYYSDEPEPYRKMNAGLVSRIFSRLGRlGFDERLEERLYDSILNAfqeqdtTVGLILPC 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2265 KGGYVVIPGLCLPKSLKPLLPVFLQGLISGSAELREQAAIGLGELIEVTSEQALKEFVIPITGPLIRIIGDRFPWQVKSA 2344
Cdd:COG5181    587 FSTVLVSLEFRGKPHLSMIVSTILKLLRSKPPDVRIRAADLMGSLAKVLKACGETKELAKLGNILYENLGEDYPEVLGSI 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2345 ILATLIILIQRGGMALKPFLPQLQTTFVKCLQDSTRTIRSSAAVALGKLSALS-TRIDP-----LVGDLMTSFQAADSGV 2418
Cdd:COG5181    667 LKAICSIYSVHRFRSMQPPISGILPSLTPILRNKHQKVVANTIALVGTICMNSpEYIGVrewmrICFELVDSLKSWNKEI 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2419 REAILSAMrGVIkhaGKSIGPAvrvRIFDLLKDLMHHEDDQVRISATSMLGVLSQYleAAQLSVLLQEVNDLSaSQNWGA 2498
Cdd:COG5181    747 RRNATETF-GCI---SRAIGPQ---DVLDILLNNLKVQERQQRVCTSVAISIVAEY--CGPFSVLPTLMSDYE-TPEANV 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2499 RHGSVLCISSLLK--HNpstiMTSSLFSSMLNSLKSSLKDekfplRESSTKALGRLLLKQLATDPSNTKVV---IDVLSS 2573
Cdd:COG5181    817 QNGVLKAMCFMFEyiGQ----ASLDYVYSITPLLEDALTD-----RDPVHRQTAMNVIRHLVLNCPGTGDEdaaIHLLNL 887

                          730       740
                   ....*....|....*....|....
gi 1063696628 2574 IVSALHDDSSEVRRRALSSLKAFA 2597
Cdd:COG5181    888 LWPNILEPSPHVIQSFDEGMESFA 911
HEAT COG1413
HEAT repeat [General function prediction only];
1688-1855 1.20e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 50.01  E-value: 1.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1688 VRSVAARAVGSLirgmGEdnfPDLVPWLFETLKSDTSNVeRYGAAQglseviaALGTDYFENILPDLIRHCSHQKASVRD 1767
Cdd:COG1413      1 VRRAAARALGRL----GD---PAAVPALIAALADEDPDV-RAAAAR-------ALGRLGDPRAVPALLEALKDPDPEVRA 65

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1768 GYLtlfkflpRSLGAQFQKylqLVLPAILDGLADENESVRDAALGAghvLVEHHATTSLPLLLPAVEDgifnDNWRIRQS 1847
Cdd:COG1413     66 AAA-------EALGRIGDP---EAVPALIAALKDEDPEVRRAAAEA---LGRLGDPAAVPALLEALKD----PDWEVRRA 128


                   ....*...
gi 1063696628 1848 SVELLGDL 1855
Cdd:COG1413    129 AARALGRL 136
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 2339-2393 3.23e-04

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 40.81  E-value: 3.23e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063696628 2339 WQVKSAILATLIILIQRGGMALKPFLPQLQTTFVKCLQDSTRTIRSSAAVALGKL 2393
Cdd:pfam13513    1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
HEAT COG1413
HEAT repeat [General function prediction only];
1503-1609 3.71e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 43.08  E-value: 3.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1503 QLSAYGVKLVLPSLLKGLEDKAWRTKQSSVQLLGAMAfcapqqlsqcLPRVVPKLTEVLTDTHPKVQSAGQLALqqvgSV 1582
Cdd:COG1413      8 ALGRLGDPAAVPALIAALADEDPDVRAAAARALGRLG----------DPRAVPALLEALKDPDPEVRAAAAEAL----GR 73

                           90       100
                   ....*....|....*....|....*..
gi 1063696628 1583 IKNPEIsslVPTLLLALTDPNEYTRHA 1609
Cdd:COG1413     74 IGDPEA---VPALIAALKDEDPEVRRA 97
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
1793-2043 1.16e-03

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 44.46  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1793 PAILDGLADENESVRDAALGAGHVLVEhhaTTSLPlllPAVEDGIFNDNWRIRQSSVELLGDLLfkvAGTSGKALLEGGS 1872
Cdd:PRK13800   655 PALVAALGDGAAAVRRAAAEGLRELVE---VLPPA---PALRDHLGSPDPVVRAAALDVLRALR---AGDAALFAAALGD 725

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1873 DDEGASTEAQgRAIIDIlgmDKRNEVLAAlymvRTDVSLSVRQAALHVWKTIVANTPKTLkeimpilmSTLISSLASPSS 1952
Cdd:PRK13800   726 PDHRVRIEAV-RALVSV---DDVESVAGA----ATDENREVRIAVAKGLATLGAGGAPAG--------DAVRALTGDPDP 789

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1953 ERRQVAGRSLGELvrklgeRVLPLIIPILSKGLKDPDVDKRQGVCIGLNEVMASAGrsqllsfmdqlIPTIRTALCDSAL 2032
Cdd:PRK13800   790 LVRAAALAALAEL------GCPPDDVAAATAALRASAWQVRQGAARALAGAAADVA-----------VPALVEALTDPHL 852

                          250
                   ....*....|.
gi 1063696628 2033 EVRESAGLAFS 2043
Cdd:PRK13800   853 DVRKAAVLALT 863
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 1525-1579 1.23e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 38.89  E-value: 1.23e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063696628 1525 WRTKQSSVQLLGAMAFCAPQQLSQCLPRVVPKLTEVLTDTHPKVQSAGQLALQQV 1579
Cdd:pfam13513    1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
 
Name Accession Description Interval E-value
HSH155 COG5181
U2 snRNP spliceosome subunit [RNA processing and modification];
1932-2597 3.35e-11

U2 snRNP spliceosome subunit [RNA processing and modification];


Pssm-ID: 227508 [Multi-domain]  Cd Length: 975  Bit Score: 69.21  E-value: 3.35e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1932 LKEIMPILMStlissLASPSSERRQVAG------RSLGELVRKLGERVLPLIIPILSkglkDPDVDKRqgvCIGLNEVMA 2005
Cdd:COG5181    205 FNKVLPMLMS-----RELEDQERHLVVKlidrllYGLDDLKVPYVHKILVVVGPLLI----DEDLKRR---CMGREIILN 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2006 SAGRSQLlSFMdqlIPTIRTALCDSALEVRESAGLAFSTLYKSAGLQAMDEIIPTLLEALEDDEMSTTALDGLKQIISVR 2085
Cdd:COG5181    273 LVYRCGL-GFS---VSSMRPDITSKDEYVRNVTGRAVGVVADALGVEELLPFLEALCGSRKSWEARHTGIRIAQQICELL 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2086 TAAVLPH------ILPKLV---HLPLSALNAHALGALAEVAG---------------AGFNTHLGTILPALLSAMGGENK 2141
Cdd:COG5181    349 GRSRLSHlgpllkCISKLLkdrSRFVRIDTANALSYLAELVGpygieqfdevlcplwEGASQHRGKELVSFLKAMGFIIP 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2142 EVQ-ELAQEAAERVVLVI-------DEEGVETLLseLLKGVSDSQASI-------------------RRSSAYLIGY--- 2191
Cdd:COG5181    429 LMSpEYACHDTREHMEIVfrefkspDEEMKKDLL--VVERICDKVGTDtpwklrdqvspeffspfwrRRSAGDRRSYkqv 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2192 FFKSSKLYLIDEAPNMISTLIVMLSDSDSTTVAVSWEALARVIGSVPK-EVLPSYIKLVRDAVSTA------RDKERRKR 2264
Cdd:COG5181    507 VLTTVILAKMGGDPRVSRKILEYYSDEPEPYRKMNAGLVSRIFSRLGRlGFDERLEERLYDSILNAfqeqdtTVGLILPC 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2265 KGGYVVIPGLCLPKSLKPLLPVFLQGLISGSAELREQAAIGLGELIEVTSEQALKEFVIPITGPLIRIIGDRFPWQVKSA 2344
Cdd:COG5181    587 FSTVLVSLEFRGKPHLSMIVSTILKLLRSKPPDVRIRAADLMGSLAKVLKACGETKELAKLGNILYENLGEDYPEVLGSI 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2345 ILATLIILIQRGGMALKPFLPQLQTTFVKCLQDSTRTIRSSAAVALGKLSALS-TRIDP-----LVGDLMTSFQAADSGV 2418
Cdd:COG5181    667 LKAICSIYSVHRFRSMQPPISGILPSLTPILRNKHQKVVANTIALVGTICMNSpEYIGVrewmrICFELVDSLKSWNKEI 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2419 REAILSAMrGVIkhaGKSIGPAvrvRIFDLLKDLMHHEDDQVRISATSMLGVLSQYleAAQLSVLLQEVNDLSaSQNWGA 2498
Cdd:COG5181    747 RRNATETF-GCI---SRAIGPQ---DVLDILLNNLKVQERQQRVCTSVAISIVAEY--CGPFSVLPTLMSDYE-TPEANV 816

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2499 RHGSVLCISSLLK--HNpstiMTSSLFSSMLNSLKSSLKDekfplRESSTKALGRLLLKQLATDPSNTKVV---IDVLSS 2573
Cdd:COG5181    817 QNGVLKAMCFMFEyiGQ----ASLDYVYSITPLLEDALTD-----RDPVHRQTAMNVIRHLVLNCPGTGDEdaaIHLLNL 887

                          730       740
                   ....*....|....*....|....
gi 1063696628 2574 IVSALHDDSSEVRRRALSSLKAFA 2597
Cdd:COG5181    888 LWPNILEPSPHVIQSFDEGMESFA 911
HEAT COG1413
HEAT repeat [General function prediction only];
1688-1855 1.20e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 50.01  E-value: 1.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1688 VRSVAARAVGSLirgmGEdnfPDLVPWLFETLKSDTSNVeRYGAAQglseviaALGTDYFENILPDLIRHCSHQKASVRD 1767
Cdd:COG1413      1 VRRAAARALGRL----GD---PAAVPALIAALADEDPDV-RAAAAR-------ALGRLGDPRAVPALLEALKDPDPEVRA 65

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1768 GYLtlfkflpRSLGAQFQKylqLVLPAILDGLADENESVRDAALGAghvLVEHHATTSLPLLLPAVEDgifnDNWRIRQS 1847
Cdd:COG1413     66 AAA-------EALGRIGDP---EAVPALIAALKDEDPEVRRAAAEA---LGRLGDPAAVPALLEALKD----PDWEVRRA 128


                   ....*...
gi 1063696628 1848 SVELLGDL 1855
Cdd:COG1413    129 AARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
2370-2489 2.19e-05

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.55  E-value: 2.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2370 TFVKCLQDSTRTIRSSAAVALGKLSAlstriDPLVGDLMTSFQAADSGVREAILSAMRgvikhagkSIGPAvrvRIFDLL 2449
Cdd:COG1413     20 ALIAALADEDPDVRAAAARALGRLGD-----PRAVPALLEALKDPDPEVRAAAAEALG--------RIGDP---EAVPAL 83

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1063696628 2450 KDLMHHEDDQVRISATSMLGVLSqylEAAQLSVLLQEVND 2489
Cdd:COG1413     84 IAALKDEDPEVRRAAAEALGRLG---DPAAVPALLEALKD 120
HEAT COG1413
HEAT repeat [General function prediction only];
2530-2630 1.36e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 44.23  E-value: 1.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2530 LKSSLKDEKFPLRESSTKALGRL-------LLKQLATDPSNT--KVVIDVLSSI---------VSALHDDSSEVRRRALS 2591
Cdd:COG1413     21 LIAALADEDPDVRAAAARALGRLgdpravpALLEALKDPDPEvrAAAAEALGRIgdpeavpalIAALKDEDPEVRRAAAE 100

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1063696628 2592 SLKAFakDNPSATmanisvigPPLAECLKDGNTPVRLAA 2630
Cdd:COG1413    101 ALGRL--GDPAAV--------PALLEALKDPDWEVRRAA 129
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 2339-2393 3.23e-04

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 40.81  E-value: 3.23e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063696628 2339 WQVKSAILATLIILIQRGGMALKPFLPQLQTTFVKCLQDSTRTIRSSAAVALGKL 2393
Cdd:pfam13513    1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
HEAT COG1413
HEAT repeat [General function prediction only];
1503-1609 3.71e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 43.08  E-value: 3.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1503 QLSAYGVKLVLPSLLKGLEDKAWRTKQSSVQLLGAMAfcapqqlsqcLPRVVPKLTEVLTDTHPKVQSAGQLALqqvgSV 1582
Cdd:COG1413      8 ALGRLGDPAAVPALIAALADEDPDVRAAAARALGRLG----------DPRAVPALLEALKDPDPEVRAAAAEAL----GR 73

                           90       100
                   ....*....|....*....|....*..
gi 1063696628 1583 IKNPEIsslVPTLLLALTDPNEYTRHA 1609
Cdd:COG1413     74 IGDPEA---VPALIAALKDEDPEVRRA 97
HEAT COG1413
HEAT repeat [General function prediction only];
2298-2469 6.53e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 42.31  E-value: 6.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2298 LREQAAIGLGELievTSEQALKefvipitgPLIRIIGDRFPwQVKSAILATLiiliqrGGMALKPFLPQLqttfVKCLQD 2377
Cdd:COG1413      1 VRRAAARALGRL---GDPAAVP--------ALIAALADEDP-DVRAAAARAL------GRLGDPRAVPAL----LEALKD 58

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2378 STRTIRSSAAVALGKLSALSTrIDPLVGDLmtsfQAADSGVREAILSAMrGVIKHAgksigpavrvRIFDLLKDLMHHED 2457
Cdd:COG1413     59 PDPEVRAAAAEALGRIGDPEA-VPALIAAL----KDEDPEVRRAAAEAL-GRLGDP----------AAVPALLEALKDPD 122

                          170
                   ....*....|..
gi 1063696628 2458 DQVRISATSMLG 2469
Cdd:COG1413    123 WEVRRAAARALG 134
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
1793-2043 1.16e-03

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 44.46  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1793 PAILDGLADENESVRDAALGAGHVLVEhhaTTSLPlllPAVEDGIFNDNWRIRQSSVELLGDLLfkvAGTSGKALLEGGS 1872
Cdd:PRK13800   655 PALVAALGDGAAAVRRAAAEGLRELVE---VLPPA---PALRDHLGSPDPVVRAAALDVLRALR---AGDAALFAAALGD 725

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1873 DDEGASTEAQgRAIIDIlgmDKRNEVLAAlymvRTDVSLSVRQAALHVWKTIVANTPKTLkeimpilmSTLISSLASPSS 1952
Cdd:PRK13800   726 PDHRVRIEAV-RALVSV---DDVESVAGA----ATDENREVRIAVAKGLATLGAGGAPAG--------DAVRALTGDPDP 789

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1953 ERRQVAGRSLGELvrklgeRVLPLIIPILSKGLKDPDVDKRQGVCIGLNEVMASAGrsqllsfmdqlIPTIRTALCDSAL 2032
Cdd:PRK13800   790 LVRAAALAALAEL------GCPPDDVAAATAALRASAWQVRQGAARALAGAAADVA-----------VPALVEALTDPHL 852

                          250
                   ....*....|.
gi 1063696628 2033 EVRESAGLAFS 2043
Cdd:PRK13800   853 DVRKAAVLALT 863
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 1525-1579 1.23e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 38.89  E-value: 1.23e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063696628 1525 WRTKQSSVQLLGAMAFCAPQQLSQCLPRVVPKLTEVLTDTHPKVQSAGQLALQQV 1579
Cdd:pfam13513    1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
HEAT COG1413
HEAT repeat [General function prediction only];
2447-2597 2.00e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 40.77  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 2447 DLLKDLMHHEDDQVRISATSMLGVLSqylEAAQLSVLLQEVNDlsasQNWGARHGSVLCISSLlkHNPSTImtsslfssm 2526
Cdd:COG1413     19 PALIAALADEDPDVRAAAARALGRLG---DPRAVPALLEALKD----PDPEVRAAAAEALGRI--GDPEAV--------- 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063696628 2527 lNSLKSSLKDEKFPLRESSTKALGRLllkqlatdpsNTKVVIDVLssiVSALHDDSSEVRRRALSSLKAFA 2597
Cdd:COG1413     81 -PALIAALKDEDPEVRRAAAEALGRL----------GDPAAVPAL---LEALKDPDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
1791-1965 3.59e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 40.00  E-value: 3.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1791 VLPAILDGLADENESVRDAALGAghvLVEHHATTSLPLLLPAVEDgifnDNWRIRQSSVELLGDLlfkvagtsgkalleg 1870
Cdd:COG1413     17 AVPALIAALADEDPDVRAAAARA---LGRLGDPRAVPALLEALKD----PDPEVRAAAAEALGRI--------------- 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1871 gsddegasteaQGRAIIDILgmdkrnevLAALymvrTDVSLSVRQAALHvwktivantpkTLKEIM-PILMSTLISSLAS 1949
Cdd:COG1413     75 -----------GDPEAVPAL--------IAAL----KDEDPEVRRAAAE-----------ALGRLGdPAAVPALLEALKD 120

                          170
                   ....*....|....*.
gi 1063696628 1950 PSSERRQVAGRSLGEL 1965
Cdd:COG1413    121 PDWEVRRAAARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
1966-2117 6.87e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 39.23  E-value: 6.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1966 VRKLGERVLPLIIPILSKGLKDPDVDKRQGVCIGLNEVMASAGrsqllsfmdqlIPTIRTALCDSALEVRESAGLAFSTL 2045
Cdd:COG1413      6 ARALGRLGDPAAVPALIAALADEDPDVRAAAARALGRLGDPRA-----------VPALLEALKDPDPEVRAAAAEALGRI 74

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063696628 2046 yksaglqAMDEIIPTLLEALEDDEMS--TTALDGLKQIisvRTAAVLPHILPKLVHlPLSALNAHALGALAEVA 2117
Cdd:COG1413     75 -------GDPEAVPALIAALKDEDPEvrRAAAEALGRL---GDPAAVPALLEALKD-PDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
1551-1699 7.48e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 39.23  E-value: 7.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1551 PRVVPKLTEVLTDTHPKVQSAGQLALQQVGSviknpeiSSLVPTLLLALTDPNEYTRH-ALDTLLQTTfvnsvDAPSLAL 1629
Cdd:COG1413     15 PAAVPALIAALADEDPDVRAAAARALGRLGD-------PRAVPALLEALKDPDPEVRAaAAEALGRIG-----DPEAVPA 82

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696628 1630 LVPIvhrgLRERSSETKKKASQIVGNMCSLVTepkdmipyigllLPEVKKVLVDPIPEVRSVAARAVGSL 1699
Cdd:COG1413     83 LIAA----LKDEDPEVRRAAAEALGRLGDPAA------------VPALLEALKDPDWEVRRAAARALGRL 136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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