NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1063721732|ref|NP_001319903|]
View 

Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

Protein Classification

solute carrier family 25 protein( domain architecture ID 13310014)

solute carrier 25 family (SLC25) protein which transfers molecules across the membranes of organelles, usually mitochondria

Gene Ontology:  GO:0016020|GO:1990542
TCDB:  2.A.29

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
513-604 1.10e-28

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 109.67  E-value: 1.10e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 513 QPTTLQTLTCGGLAGSAAAFFTTPFDVVKTRLQTQIPGSRNQHPSVYQTLQSIRRQEGLRGLYRGLIPRLVMYMSQGAIF 592
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81
                          90
                  ....*....|..
gi 1063721732 593 FASYEFYKSVLS 604
Cdd:pfam00153  82 FGTYETLKRLLL 93
PTZ00168 super family cl33169
mitochondrial carrier protein; Provisional
333-599 2.85e-25

mitochondrial carrier protein; Provisional


The actual alignment was detected with superfamily member PTZ00168:

Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 105.39  E-value: 2.85e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 333 GALAGISVSLCLHPLDTVKTMIQScrleEKSLcntgrsiiSERGFSGLYRGIASNIASSAPISALYTFTYETVKGTLLPL 412
Cdd:PTZ00168   10 GALSGVIVDAVLYPIDSIKTNIQA----KKSF--------SFSDIKKLYSGILPTLVGTVPASAFFYCFYELSKKLLTEY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 413 FPKEYCSLAHCLAGGSASIATSFIFTPSERIKQQMQVSSHYrNCWTALVGIIQKGGLLS-LYAGWTAVLCRNIPHSIIKF 491
Cdd:PTZ00168   78 RENISKTNLYLISTSIAEITACIVRLPFEIVKQNMQVSGNI-SVLKTIYEITQREGLPSfLGKSYFVMIVREIPFDCIQY 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 492 YVYENMKQMVLPSPGPCGEMAqpTTLQTLTCGGLAGSAAAFFTTPFDVVKTRlqtQIPGSRnqhpSVYQTLQSIrRQEGL 571
Cdd:PTZ00168  157 FLWETLKEKAKKDFGKFSKKY--PSITSAICGGLAGGIAGFLTTPVDVIKSR---QIIYGK----SYIETVTEI-AEEGY 226
                         250       260
                  ....*....|....*....|....*...
gi 1063721732 572 RGLYRGLIPRLVMYMSQGAIFFASYEFY 599
Cdd:PTZ00168  227 LTFYKGCCFRSSYLFFGGLIFFGSLRFF 254
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
513-604 1.10e-28

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 109.67  E-value: 1.10e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 513 QPTTLQTLTCGGLAGSAAAFFTTPFDVVKTRLQTQIPGSRNQHPSVYQTLQSIRRQEGLRGLYRGLIPRLVMYMSQGAIF 592
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81
                          90
                  ....*....|..
gi 1063721732 593 FASYEFYKSVLS 604
Cdd:pfam00153  82 FGTYETLKRLLL 93
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
333-599 2.85e-25

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 105.39  E-value: 2.85e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 333 GALAGISVSLCLHPLDTVKTMIQScrleEKSLcntgrsiiSERGFSGLYRGIASNIASSAPISALYTFTYETVKGTLLPL 412
Cdd:PTZ00168   10 GALSGVIVDAVLYPIDSIKTNIQA----KKSF--------SFSDIKKLYSGILPTLVGTVPASAFFYCFYELSKKLLTEY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 413 FPKEYCSLAHCLAGGSASIATSFIFTPSERIKQQMQVSSHYrNCWTALVGIIQKGGLLS-LYAGWTAVLCRNIPHSIIKF 491
Cdd:PTZ00168   78 RENISKTNLYLISTSIAEITACIVRLPFEIVKQNMQVSGNI-SVLKTIYEITQREGLPSfLGKSYFVMIVREIPFDCIQY 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 492 YVYENMKQMVLPSPGPCGEMAqpTTLQTLTCGGLAGSAAAFFTTPFDVVKTRlqtQIPGSRnqhpSVYQTLQSIrRQEGL 571
Cdd:PTZ00168  157 FLWETLKEKAKKDFGKFSKKY--PSITSAICGGLAGGIAGFLTTPVDVIKSR---QIIYGK----SYIETVTEI-AEEGY 226
                         250       260
                  ....*....|....*....|....*...
gi 1063721732 572 RGLYRGLIPRLVMYMSQGAIFFASYEFY 599
Cdd:PTZ00168  227 LTFYKGCCFRSSYLFFGGLIFFGSLRFF 254
Mito_carr pfam00153
Mitochondrial carrier protein;
328-410 7.15e-17

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 76.16  E-value: 7.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 328 RHAFAGALAGISVSLCLHPLDTVKTMIQSCRLEEKSLC----NTGRSIISERGFSGLYRGIASNIASSAPISALYTFTYE 403
Cdd:pfam00153   7 ASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGrgilDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTYE 86

                  ....*..
gi 1063721732 404 TVKGTLL 410
Cdd:pfam00153  87 TLKRLLL 93
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
424-603 1.02e-06

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 50.92  E-value: 1.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 424 LAGG-SASIATSfIFTPSERIKQQMQVSSHYRNCWTALV----GII-------QKGGLLSLYAGWTAVLCRNIPHSIIKF 491
Cdd:PTZ00169   12 LMGGiSAAISKT-AVAPIERVKMLIQTQDSIPEIKSGKVprysGIVncfrrvsKEQGVLSLWRGNTANVIRYFPTQAFNF 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 492 YVYENMKQMvLPspgpcgEMAQPTTLQTLTC-----GGLAGSAAAFFTTPFDVVKTRLQTQI-PGSRNQHPSVYQTLQSI 565
Cdd:PTZ00169   91 AFKDYFKNM-FP------KYNQKTDFWKFFGvnilsGGLAGASSLLIVYPLDFARTRLASDIgKGGDREFTGLFDCLMKI 163
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063721732 566 RRQEGLRGLYRGL---IPRLVMYmsQGAiFFASYEFYKSVL 603
Cdd:PTZ00169  164 SKQTGFLSLYQGFgvsVQGIIVY--RGA-YFGLYDSAKALL 201
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
513-604 1.10e-28

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 109.67  E-value: 1.10e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 513 QPTTLQTLTCGGLAGSAAAFFTTPFDVVKTRLQTQIPGSRNQHPSVYQTLQSIRRQEGLRGLYRGLIPRLVMYMSQGAIF 592
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81
                          90
                  ....*....|..
gi 1063721732 593 FASYEFYKSVLS 604
Cdd:pfam00153  82 FGTYETLKRLLL 93
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
333-599 2.85e-25

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 105.39  E-value: 2.85e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 333 GALAGISVSLCLHPLDTVKTMIQScrleEKSLcntgrsiiSERGFSGLYRGIASNIASSAPISALYTFTYETVKGTLLPL 412
Cdd:PTZ00168   10 GALSGVIVDAVLYPIDSIKTNIQA----KKSF--------SFSDIKKLYSGILPTLVGTVPASAFFYCFYELSKKLLTEY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 413 FPKEYCSLAHCLAGGSASIATSFIFTPSERIKQQMQVSSHYrNCWTALVGIIQKGGLLS-LYAGWTAVLCRNIPHSIIKF 491
Cdd:PTZ00168   78 RENISKTNLYLISTSIAEITACIVRLPFEIVKQNMQVSGNI-SVLKTIYEITQREGLPSfLGKSYFVMIVREIPFDCIQY 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 492 YVYENMKQMVLPSPGPCGEMAqpTTLQTLTCGGLAGSAAAFFTTPFDVVKTRlqtQIPGSRnqhpSVYQTLQSIrRQEGL 571
Cdd:PTZ00168  157 FLWETLKEKAKKDFGKFSKKY--PSITSAICGGLAGGIAGFLTTPVDVIKSR---QIIYGK----SYIETVTEI-AEEGY 226
                         250       260
                  ....*....|....*....|....*...
gi 1063721732 572 RGLYRGLIPRLVMYMSQGAIFFASYEFY 599
Cdd:PTZ00168  227 LTFYKGCCFRSSYLFFGGLIFFGSLRFF 254
Mito_carr pfam00153
Mitochondrial carrier protein;
328-410 7.15e-17

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 76.16  E-value: 7.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 328 RHAFAGALAGISVSLCLHPLDTVKTMIQSCRLEEKSLC----NTGRSIISERGFSGLYRGIASNIASSAPISALYTFTYE 403
Cdd:pfam00153   7 ASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGrgilDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTYE 86

                  ....*..
gi 1063721732 404 TVKGTLL 410
Cdd:pfam00153  87 TLKRLLL 93
Mito_carr pfam00153
Mitochondrial carrier protein;
420-502 2.70e-15

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 71.53  E-value: 2.70e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 420 LAHCLAGGSASIATSFIFTPSERIKQQMQVSSH-----YRNCWTALVGIIQKGGLLSLYAGWTAVLCRNIPHSIIKFYVY 494
Cdd:pfam00153   6 LASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgkskGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85

                  ....*...
gi 1063721732 495 ENMKQMVL 502
Cdd:pfam00153  86 ETLKRLLL 93
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
424-603 1.02e-06

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 50.92  E-value: 1.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 424 LAGG-SASIATSfIFTPSERIKQQMQVSSHYRNCWTALV----GII-------QKGGLLSLYAGWTAVLCRNIPHSIIKF 491
Cdd:PTZ00169   12 LMGGiSAAISKT-AVAPIERVKMLIQTQDSIPEIKSGKVprysGIVncfrrvsKEQGVLSLWRGNTANVIRYFPTQAFNF 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 492 YVYENMKQMvLPspgpcgEMAQPTTLQTLTC-----GGLAGSAAAFFTTPFDVVKTRLQTQI-PGSRNQHPSVYQTLQSI 565
Cdd:PTZ00169   91 AFKDYFKNM-FP------KYNQKTDFWKFFGvnilsGGLAGASSLLIVYPLDFARTRLASDIgKGGDREFTGLFDCLMKI 163
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063721732 566 RRQEGLRGLYRGL---IPRLVMYmsQGAiFFASYEFYKSVL 603
Cdd:PTZ00169  164 SKQTGFLSLYQGFgvsVQGIIVY--RGA-YFGLYDSAKALL 201
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
333-577 4.23e-06

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 49.00  E-value: 4.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 333 GALAGISVSLcLHPLDTVKTMIQ---------SCRLEEKS-LCNTGRSIISERGFSGLYRGIASNIASSAPISAlYTFTY 402
Cdd:PTZ00169   15 GISAAISKTA-VAPIERVKMLIQtqdsipeikSGKVPRYSgIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQA-FNFAF 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 403 ETVKGTLLPLFPKE------YCslAHCLAGGSASIATSFIFTPSE--RIKQQMQVSSHYRNCWTALVGIIQK----GGLL 470
Cdd:PTZ00169   93 KDYFKNMFPKYNQKtdfwkfFG--VNILSGGLAGASSLLIVYPLDfaRTRLASDIGKGGDREFTGLFDCLMKiskqTGFL 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721732 471 SLYAGWTAVLCRNIPHSIIKFYVYENMKQMVLPSPGPCGEMAQPTTLQTLTcgglagSAAAFFTTPFDVVKTRLQT---Q 547
Cdd:PTZ00169  171 SLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYKWAVAQTVT------ILAGLISYPFDTVRRRMMMmsgR 244
                         250       260       270
                  ....*....|....*....|....*....|
gi 1063721732 548 IPGSRNQHPSVYQTLQSIRRQEGLRGLYRG 577
Cdd:PTZ00169  245 KAKSEIQYTGTLDCWKKILKNEGLGGFFKG 274
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH
HHS Vulnerability Disclosure