|
Name |
Accession |
Description |
Interval |
E-value |
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
80-788 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 565.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 80 DLQQFKKisDIENFFINledNPKGVIPCMNAAVhkVLFDQWETNEfeNVMKINVRLHNYPESsISLKNLRAAYIGKLVTV 159
Cdd:COG1241 41 DLYSFDP--DLADDLLE---NPDEVLEAAEEAL--REIDLEPYDV--SLGDAHVRITNLPET-VPIRDIRSDHIGKLISV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 160 HGTVVKVSTVKPLVTQMAFDCGKCKTGITREFTDGKFSPPLKCDshGC-KSKTFTPIRSSAQTIDFQKIRVQElqKPEDH 238
Cdd:COG1241 111 EGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECP--GCgRQGPFKLLPEKSEFIDAQKIRIQE--PPEDL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 239 EEGRVPRTVECELMEDLVDICIPGDVVTVTGIIGVINNymDIGGGKSKtknqgFYYLFIEAVSVKntKRQSAFENSEdss 318
Cdd:COG1241 187 PGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQR--TSGRGKST-----IFDLYLEANSIE--VEEKEFEEIE--- 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 319 ssaqtadvgdlysFSQRDLEFIVKFKEeyGSDTFRRILHSVCPSIYGHEIVKAGITLSLFGGVRKHSMDRNKVpvRGDIH 398
Cdd:COG1241 255 -------------ITEEDEEKIKELSK--DPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRI--RGDIH 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 399 VIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTRAGLTVAVVKDS-MTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQ 477
Cdd:COG1241 318 ILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDfGTGRWTLEAGALVLADGGLACIDELDKMREEDR 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 478 -ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPVGGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSE 556
Cdd:COG1241 398 sALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELAR 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 557 HIMSLHSASG----ETSPALKKFKPvnaasqnagyanmhaegnsllsrlrldsekdddfsPVPGQLLRKYISYARNFVNP 632
Cdd:COG1241 478 HILKVHRAGElleqEIEEETEEVKP-----------------------------------EIDPDLLRKYIAYARRNVFP 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 633 KMSKDAGEIIQKFYLKLRDHNTSADST-PITARQLESLVRLAQARARVDLREEITVQDAMDVVEIMKESLYDKLID-EHG 710
Cdd:COG1241 523 VLTEEAKDLIEDFYVDMRKKGEDEDSPvPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDpETG 602
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 711 VVDF-----GRSggMSQQKEAKRFLSALDKQSElQQKDCFSVSEMYSLADRIGLRVPDIDTFLENLNIAGYLLKKGPKTY 785
Cdd:COG1241 603 KFDIdvietGTS--KSQRDKMKLIKDIIKELEE-ESSGGAPIEDVIEEAEEEGIDREKAEELIEKLKRKGEIYEPKPGHY 679
|
...
gi 1063708510 786 QVL 788
Cdd:COG1241 680 KKV 682
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
354-700 |
1.80e-175 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 505.53 E-value: 1.80e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 354 RILHSVCPSIYGHEIVKAGITLSLFGGVRKHSMDRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTR 433
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 434 AGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPVG 513
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 514 GHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDElldkqVSEHIMSLHsasgetspalkkfkpvnaasqnagyanmhae 593
Cdd:cd17759 161 GHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSE-----EHDHLLSEH------------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 594 gnsllsrlrldsekdddfspvpGQLLRKYISYARNFVNPKMSKDAGEIIQKFYLKLRDHNTSADSTPITARQLESLVRLA 673
Cdd:cd17759 205 ----------------------HQLLRKYISYARQYVNPVLSKDASEALQEFYLELRKQNQLADSSPITTRQLESLIRLT 262
|
330 340
....*....|....*....|....*..
gi 1063708510 674 QARARVDLREEITVQDAMDVVEIMKES 700
Cdd:cd17759 263 EARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
143-701 |
8.80e-167 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 492.16 E-value: 8.80e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 143 ISLKNLRAAYIGKLVTVHGTVVKVSTVKPLVTQMAFDCGKCKTGITREFTDGKFSPPLKCDSHGCKSKTFTPIRSSAQT- 221
Cdd:smart00350 3 SSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTPFSLNHERSTf 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 222 IDFQKIRVQELqkPEDHEEGRVPRTVECELMEDLVDICIPGDVVTVTGIigvinnYMDIGGGKSKTKNQGFYYL--FIEA 299
Cdd:smart00350 83 IDFQKIKLQES--PEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGI------YRNVPYGFKLNTVKGLPVFatYIEA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 300 VSVKNTKRQSAFENSEDSSSSAQTADVGDLYSFSQRDlefivkfkeeygsDTFRRILHSVCPSIYGHEIVKAGITLSLFG 379
Cdd:smart00350 155 NHVRKLDYKRSFEDSSFSVQSLSDEEEEEIRKLSKDP-------------DIYERLARSLAPSIYGHEDIKKAILLLLFG 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 380 GVRKHSmdRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTRAGLTVAVVKDSMTNDYAFEAGAMVLA 459
Cdd:smart00350 222 GVHKNL--PDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLA 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 460 DGGLCCIDEFDKMTTEHQ-ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPVGGHYNRAKTVNENLKMSAALLSRFDL 538
Cdd:smart00350 300 DNGVCCIDEFDKMDDSDRtAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 539 VFILLDKPDELLDKQVSEHIMSLHsasgetspalkkfkpvnaasqnagyanmhaegnsllsRLRLDSEKDDDFSPVPGQL 618
Cdd:smart00350 380 LFVVLDEVDEERDRELAKHVVDLH-------------------------------------RYSHPEEDEAFEPPLSQEK 422
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 619 LRKYISYARNFVNPKMSKDAGEIIQKFYLKLRDH---NTSADSTPITARQLESLVRLAQARARVDLREEITVQDAMDVVE 695
Cdd:smart00350 423 LRKYIAYAREKIKPKLSEEAADKLVKAYVDLRKEdsqTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIR 502
|
....*.
gi 1063708510 696 IMKESL 701
Cdd:smart00350 503 LLRESI 508
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
354-700 |
1.10e-129 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 389.01 E-value: 1.10e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 354 RILHSVCPSIYGHEIVKAGITLSLFGGVRKhsMDRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTR 433
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQK--ILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 434 AGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQ-ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPV 512
Cdd:cd17706 79 AGLTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRtALHEAMEQQTISIAKAGIVTTLNARCSILAAANPK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 513 GGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLHSASgetSPALKKfkpvnaasqnagyanmha 592
Cdd:cd17706 159 GGRYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGS---DPEEQV------------------ 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 593 egnsllsrlrldsEKDDDFSPVPGQLLRKYISYARNfVNPKMSKDAGEIIQKFYLKLRDHNTSADSTPITARQLESLVRL 672
Cdd:cd17706 218 -------------KPEEDGIPIDIELLRKYILYARQ-IHPKISEEAREKLVRWYVELRKESERRSTIPITARQLESVIRL 283
|
330 340
....*....|....*....|....*...
gi 1063708510 673 AQARARVDLREEITVQDAMDVVEIMKES 700
Cdd:cd17706 284 AEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
354-697 |
1.18e-116 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 355.22 E-value: 1.18e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 354 RILHSVCPSIYGHEIVKAGITLSLFGGVRKHSMDrnKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTR 433
Cdd:cd17761 2 KIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPD--GTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 434 AGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQ-ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPV 512
Cdd:cd17761 80 AGLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRsALHEAMEQQTISIAKAGIVATLNARAAVLAAANPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 513 GGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLHSAsGETSpalkKFKPVnaasqnagyanmha 592
Cdd:cd17761 160 FGRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSG-GEMR----EIKPE-------------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 593 egnsllsrlrldsekdddfspVPGQLLRKYISYARNFVNPKMSKDAGEIIQKFYLKLRDHNTSADS-TPITARQLESLVR 671
Cdd:cd17761 221 ---------------------IDPDLLRKYIAYARKNVRPVLTEEAKQLIKDFYVEMRKSGQETPSpVPITARQLEALVR 279
|
330 340
....*....|....*....|....*.
gi 1063708510 672 LAQARARVDLREEITVQDAMDVVEIM 697
Cdd:cd17761 280 LSEASARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
336-562 |
4.77e-116 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 350.29 E-value: 4.77e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 336 DLEFIVKFKEEYgsDTFRRILHSVCPSIYGHEIVKAGITLSLFGGVRKHSMDRNKVpvRGDIHVIIVGDPGLGKSQLLQA 415
Cdd:pfam00493 1 DEEEIKELAKRP--DIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRL--RGDINVLLVGDPGTAKSQLLKY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 416 AAAISPRGIYVCGNATTRAGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTE-HQALLEAMEQQCVSVAKAG 494
Cdd:pfam00493 77 VEKIAPRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEdRVALHEAMEQQTISIAKAG 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063708510 495 LVASLSARTSVIAAANPVGGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLH 562
Cdd:pfam00493 157 IVATLNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
358-700 |
4.36e-112 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 343.58 E-value: 4.36e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 358 SVCPSIYGHEIVKAGITLSLFGGVRKHSmdRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTRAGLT 437
Cdd:cd17757 5 SIAPSIYGHEEVKKGILLMLLGGVHKIT--REGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGLT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 438 VAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQ-ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPVGGHY 516
Cdd:cd17757 83 AAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQvAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGRY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 517 NRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLHSAsgetspalkkfkpVNAASQnagyanmhaegns 596
Cdd:cd17757 163 DRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSK-------------REEAIE------------- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 597 llsrlrldsekdddfSPVPGQLLRKYISYARNFvNPKMSKDAGEIIQKFYLKLRDHNTSADSTP---ITARQLESLVRLA 673
Cdd:cd17757 217 ---------------PPFTAEQLKRYIAYARTF-KPKLTKEAKDELVEQYKELRQDDASGSTRSsyrITVRQLESLIRLS 280
|
330 340
....*....|....*....|....*..
gi 1063708510 674 QARARVDLREEITVQDAMDVVEIMKES 700
Cdd:cd17757 281 EAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
354-700 |
2.34e-103 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 320.92 E-value: 2.34e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 354 RILHSVCPSIYGHEIVKAGITLSLFGGVRKhSMDRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTR 433
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRK-DFTKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 434 AGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQALL-EAMEQQCVSVAKAGLVASLSARTSVIAAANPV 512
Cdd:cd17755 80 VGLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLhEVMEQQTLSIAKAGIITTLNARTSILASANPI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 513 GGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLHSASGEtspalkkfkpvnaasqnagyanmha 592
Cdd:cd17755 160 GSRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTP------------------------- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 593 egnsllsrlrlDSEKDDDFSPvpgQLLRKYISYARNFVNPKMSKDAGEIIQKFYLKLRDHNTSADSTpITA--RQLESLV 670
Cdd:cd17755 215 -----------EHIQDEVLDV---EVLTDYISYAREHIHPKLSEEAAQELVQAYVDMRKMGSDARKR-ITAtpRQLESLI 279
|
330 340 350
....*....|....*....|....*....|
gi 1063708510 671 RLAQARARVDLREEITVQDAMDVVEIMKES 700
Cdd:cd17755 280 RLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
354-700 |
7.94e-101 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 314.77 E-value: 7.94e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 354 RILHSVCPSIYGHEIVKAGITLSLFGGVRKHSMDRNKVpvRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTR 433
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRI--RGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 434 AGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKM-----TTEHqallEAMEQQCVSVAKAGLVASLSARTSVIAA 508
Cdd:cd17753 79 VGLTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMndqdrTSIH----EAMEQQSISISKAGIVTSLQARCSVIAA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 509 ANPVGGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLHSASgetSPALKKFKPVNAASQNAGya 588
Cdd:cd17753 155 ANPIGGRYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRS---HPENDEDREGEEEKNQRQ-- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 589 nmhaegnsllsrlrldSEKDDDFSPVPGQLLRKYISYARNFVNPKMSKDAGEIIQKFYLKLRDHNTSADSTPITARQLES 668
Cdd:cd17753 230 ----------------RPKETKVEPIPQELLRKYIHYAREKVRPKLNQMDMDKVSRVYADLRKESMATGSLPITVRHLES 293
|
330 340 350
....*....|....*....|....*....|..
gi 1063708510 669 LVRLAQARARVDLREEITVQDAMDVVEIMKES 700
Cdd:cd17753 294 IIRISEAHAKMHLREYVSEEDVDMAIRVMLDS 325
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
354-700 |
1.26e-95 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 300.84 E-value: 1.26e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 354 RILHSVCPSIYGHEIVKAGITLSLFGGVRKHSMDrnKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTR 433
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPD--GMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 434 AGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQ-ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPV 512
Cdd:cd17756 79 AGLTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRvAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 513 GGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLHSASGETSPalkkfkpvnaasqnagyanmha 592
Cdd:cd17756 159 FGRYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQ---------------------- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 593 egnsllsRLRLDSEKDDDFspvpgqlLRKYISYARNFVNPKMSKDAGEIIQKFYLKLR------DHNTSADST-PITARQ 665
Cdd:cd17756 217 -------SQENEGEIPISK-------LKRYIAYCRAKCAPRLSEEAAEKLSNHYVTIRkdvrqnELESDNRSSiPITVRQ 282
|
330 340 350
....*....|....*....|....*....|....*
gi 1063708510 666 LESLVRLAQARARVDLREEITVQDAMDVVEIMKES 700
Cdd:cd17756 283 LEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
354-700 |
1.34e-94 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 297.78 E-value: 1.34e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 354 RILHSVCPSIYGHEIVKAGITLSLFGGVRKHSmdrNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTR 433
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRG---DGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 434 AGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMT-TEHQALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPV 512
Cdd:cd17758 78 VGLTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDeSDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 513 GGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLHsasgetspalkkfkpvnaasqnagyanMHA 592
Cdd:cd17758 158 YGRYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVH---------------------------QHN 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 593 EgnsllsrlrldsEKDDDFSPVPGQLLRKYISYARNFvNPKMSKDAGEIIQKFYLKLR-DHNTSADSTPITARQLESLVR 671
Cdd:cd17758 211 K------------QPDSDFEPLDPKLLRAYIALAKRK-RPTVPPALADYIVQAYVEMRqEAKRSKDFTFTTPRTLLAILR 277
|
330 340
....*....|....*....|....*....
gi 1063708510 672 LAQARARVDLREEITVQDAMDVVEIMKES 700
Cdd:cd17758 278 LSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
358-698 |
1.46e-91 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 289.75 E-value: 1.46e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 358 SVCPSIYGHEIVKAGITLSLFGGVRKhsMDRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTRAGLT 437
Cdd:cd17754 5 SLAPSIYGHEYIKKAILLMLLGGVEK--NLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGLT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 438 VAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQ-ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPVGGHY 516
Cdd:cd17754 83 AAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRvAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGRY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 517 NRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMSLHSasgetspalkkfkpvnaasqnagYAnmhaegns 596
Cdd:cd17754 163 DVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHR-----------------------YI-------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 597 llsrlrldsekdddfspvpgQLLRKYISYARNFVNPKMSKDAGEIIQKFYLKLRDH----NTSADSTPITARQLESLVRL 672
Cdd:cd17754 212 --------------------KFLRKYIHYAKERIKPKLTQEAAEYIAEEYADLRNDdntkTDKARTSPITARTLETLIRL 271
|
330 340
....*....|....*....|....*.
gi 1063708510 673 AQARARVDLREEITVQDAMDVVEIMK 698
Cdd:cd17754 272 ATAHAKARLSKTVDKVDAEVALNLLR 297
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
121-753 |
6.99e-88 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 297.68 E-value: 6.99e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 121 ETNEFENVMKINVRLHNYPESSiSLKNLRAAYIGKLVTVHGTVVKVSTVKPLVTQMAFDC-GKCKTGI------TREFTD 193
Cdd:PTZ00111 195 DLSLENNSFFPRARLMNKPVSD-CVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCrGQKKIGLndyqpcTCEHYE 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 194 ----GKFSPPLKCDShgCKSK-TF-----TPIRSSAQTIDFQKIRVQELQKPEDHEEGRVP-------------RTVECE 250
Cdd:PTZ00111 274 yviqGEVNEPLLCNE--CNSKyTFelnhnMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDnsglngeiymkdnEVINLN 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 251 LMEDLVDICIPGDVVTVTGIIGVINNYMDIgggKSKTKNQgFYYLFIEAVSVKNTKRQSAFENSEDSSSSAQTADVGDLY 330
Cdd:PTZ00111 352 LYDDLIDSVKTGDRVTVVGILKVTPIRTST---TRRTLKS-LYTYFVNVIHVKVINSTNANQPEKGLKYLGNENDFSDLQ 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 331 SFSQRDLEfivkfkeeYGSDTFRRILHSVCPSIYGHEIVKAGITLSLFGGvRKHSMDRNKVP--------VRGDIHVIIV 402
Cdd:PTZ00111 428 VYKILELS--------RNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSG-NKNSSDFNKSPdacykvdnFRGIINVLLC 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 403 GDPGLGKSQLLQAAAAISPRGIYVCGNATTRAGLTVAV-VKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQALL- 480
Cdd:PTZ00111 499 GDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLy 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 481 EAMEQQCVSVAKAGLVASLSARTSVIAAANPVGGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMS 560
Cdd:PTZ00111 579 EVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 561 LHSASGETSpalkkfkpVNAASQNAGYAN-MHAEGNSllsrlrLDSEKDDDFSPVpgQLLRKYISYARNFVNPKMSKDAG 639
Cdd:PTZ00111 659 DFLLPHMTG--------SGNDEDTYDRSNtMHVEDES------LRSEKDYNKNDL--DMLRMYIKFSKLHCFPKLSDEAK 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 640 EIIQKFYLKLRDHN------------------------TSADSTPITARQLESLVRLAQARARVDLREEITVQDAMDVVE 695
Cdd:PTZ00111 723 KVITREYVKMRQGNfqtsnldelehaqedddddlyyqsSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQ 802
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063708510 696 IMKESLYDKLIDE-HGVVDFGR-SGGMSQQKEAK------RFLSALDKQSELQQKDCFSVSEMYSL 753
Cdd:PTZ00111 803 IVKSSTFQSLVDPtTGKIDFDQlHQGITTNKMQQlnqmyeQVLSVLTRSSNQDSNKSLDLNEVLSL 868
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
355-700 |
1.62e-84 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 270.96 E-value: 1.62e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 355 ILHSVCPSIYGHEIVKAGITLSLFGGVrkHSMDRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPRGIYVCGNATTRA 434
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGV--QRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 435 GLTVAVVKDSmtNDYAFEAGAMVLADGGLCCIDEFDKMtTEHQ--ALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPv 512
Cdd:cd17760 80 GLTVTAVKDG--GEWNLEAGALVLADGGLCCIDEFNSL-KEHDrtSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 513 GGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKQVSEHIMslhSASGETSPALKKFkpvnaasqnagyanmha 592
Cdd:cd17760 156 KGQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL---ENKGEPSKSSKLW----------------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 593 egnsllsrlrldsekdddfspvPGQLLRKYISYARNFvNPKMSKDAGEIIQKFYlKLRDHNTSADSTPITARQLESLVRL 672
Cdd:cd17760 216 ----------------------SMEKMRTYFCLIKNL-RPVLSDEANAILLRYY-QLQRQSDCRNAARTTIRMLESLIRL 271
|
330 340
....*....|....*....|....*...
gi 1063708510 673 AQARARVDLREEITVQDAMDVVEIMKES 700
Cdd:cd17760 272 AEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
144-274 |
1.10e-35 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 131.07 E-value: 1.10e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 144 SLKNLRAAYIGKLVTVHGTVVKVSTVKPLVTQMAFDCGKCKTGITREFTdgkfsPPLKCDSHGCKSK-TFTPIRSSAQTI 222
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKIT-----EPTKCPNPECGNKdPFKLVHEKSKFV 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1063708510 223 DFQKIRVQELqkPEDHEEGRVPRTVECELMEDLVDICIPGDVVTVTGIIGVI 274
Cdd:pfam17207 76 DFQKIKIQES--PEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVV 125
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
617-701 |
2.59e-33 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 123.04 E-value: 2.59e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 617 QLLRKYISYARNFVNPKMSKDAGEIIQKFYLKLR-DHNTSADSTPITARQLESLVRLAQARARVDLREEITVQDAMDVVE 695
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELRkESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIR 80
|
....*.
gi 1063708510 696 IMKESL 701
Cdd:pfam17855 81 LLKESL 86
|
|
| MCM8_WHD |
cd22247 |
winged-helix domain (WHD) found in minichromosome maintenance 8 (MCM8) and similar proteins; ... |
723-788 |
3.94e-25 |
|
winged-helix domain (WHD) found in minichromosome maintenance 8 (MCM8) and similar proteins; MCM8 is a DNA helicase that is a component of the MCM8-MCM9 complex, which is involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR). The MCM8-MCM9 complex is also required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting its nuclease activity. This model corresponds to the C-terminal winged-helix domain (WHD) of MCM8, which mediates protein-nucleic acid interaction, as well as protein-protein interaction.
Pssm-ID: 439328 [Multi-domain] Cd Length: 66 Bit Score: 98.71 E-value: 3.94e-25
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063708510 723 QKEAKRFLSALDKQSELQQKDCFSVSEMYSLADRIGLRVPDIDTFLENLNIAGYLLKKGPKTYQVL 788
Cdd:cd22247 1 RKQAKRFVSALQREAERKGNNLFTVDELKQIAKELGLQVDDFDDFIESLNNQGYLLKKGPNLYQLQ 66
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
398-536 |
5.57e-09 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 54.99 E-value: 5.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 398 HVIIVGDPGLGKSQLLQ-AAAAISPRG--IYVCGNATTRAGLTVAVvkDSMTNDYAFEAGAMVLA--DGGLCCIDEFDKM 472
Cdd:pfam07728 1 GVLLVGPPGTGKTELAErLAAALSNRPvfYVQLTRDTTEEDLFGRR--NIDPGGASWVDGPLVRAarEGEIAVLDEINRA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063708510 473 TTEHQ-ALLEAMEQQCVSVAKAG-LVASLSARTSVIAAANPVGghynraKTVNEnlkMSAALLSRF 536
Cdd:pfam07728 79 NPDVLnSLLSLLDERRLLLPDGGeLVKAAPDGFRLIATMNPLD------RGLNE---LSPALRSRF 135
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
398-562 |
2.22e-06 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 50.17 E-value: 2.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 398 HVIIVGDPGLGKSQLLQA-AAAIsprgiyvcgnattraGLTVAVVK---DSM------TNDYAFEAGAMVLADGGLCC-- 465
Cdd:COG0714 33 HLLLEGVPGVGKTTLAKAlARAL---------------GLPFIRIQftpDLLpsdilgTYIYDQQTGEFEFRPGPLFAnv 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 466 --IDEFDKMTTEHQ-ALLEAMEQQCVSVakAGLVASLSARTSVIAAANPVG--GHYNraktvnenlkMSAALLSRFdLVF 540
Cdd:COG0714 98 llADEINRAPPKTQsALLEAMEERQVTI--PGGTYKLPEPFLVIATQNPIEqeGTYP----------LPEAQLDRF-LLK 164
|
170 180
....*....|....*....|....*..
gi 1063708510 541 ILLDKPD-----ELLDKQVSEHIMSLH 562
Cdd:COG0714 165 LYIGYPDaeeerEILRRHTGRHLAEVE 191
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
398-542 |
1.16e-05 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 45.99 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 398 HVIIVGDPGLGKSQLLQAAAAISPRGIYVCgNATTRAGLTVAVVKDSMTNDYAFEAGAMVLADGGLCC--IDEFDKMTTE 475
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPGAPF-LYLNASDLLEGLVVAELFGHFLVRLLFELAEKAKPGVlfIDEIDSLSRG 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063708510 476 -HQALLEAMEQqcvsvakAGLVASLSARTSVIAAANPvgghynraktvNENLKMSAALLSRFDLVFIL 542
Cdd:cd00009 100 aQNALLRVLET-------LNDLRIDRENVRVIGATNR-----------PLLGDLDRALYDRLDIRIVI 149
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
398-544 |
1.17e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.83 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 398 HVIIVGDPGLGKSQLLQAAAAISPRG----IYVCGNATTRAGLTVAVVKDSMTNDYAFEAGAMV--------LADGGLCC 465
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPgggvIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLrlalalarKLKPDVLI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063708510 466 IDEFDKMTTEHQALLEAMEQqcvsVAKAGLVASLSARTSVIAAANPvgghynraktvnENLKMSAALLSRFDLVFILLD 544
Cdd:smart00382 84 LDEITSLLDAEQEALLLLLE----ELRLLLLLKSEKNLTVILTTND------------EKDLGPALLRRRFDRRIVLLL 146
|
|
| PRK09862 |
PRK09862 |
ATP-dependent protease; |
395-574 |
8.14e-05 |
|
ATP-dependent protease;
Pssm-ID: 182120 [Multi-domain] Cd Length: 506 Bit Score: 46.13 E-value: 8.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 395 GDIHVIIVGDPGLGKSQL----------LQAAAAISPRGIYVCGNATT---------------RAGLTVAVVKDSMTndy 449
Cdd:PRK09862 209 GGHNLLLIGPPGTGKTMLasringllpdLSNEEALESAAILSLVNAESvqkqwrqrpfrsphhSASLTAMVGGGAIP--- 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 450 afEAGAMVLADGGLCCIDE---FDKMTTEhqALLEAMEQQCVSVAKAGLVASLSARTSVIAAANPV-GGHY----NRA-- 519
Cdd:PRK09862 286 --GPGEISLAHNGVLFLDElpeFERRTLD--ALREPIESGQIHLSRTRAKITYPARFQLVAAMNPSpTGHYqgnhNRCtp 361
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1063708510 520 -KTVNENLKMSAALLSRFDLVF-ILLDKPDelldkqvsehIMSLHSASGETSPALKK 574
Cdd:PRK09862 362 eQTLRYLNRLSGPFLDRFDLSLeIPLPPPG----------ILSKTVVPGESSATVKQ 408
|
|
| AAA_3 |
pfam07726 |
ATPase family associated with various cellular activities (AAA); This Pfam entry includes some ... |
398-512 |
2.98e-04 |
|
ATPase family associated with various cellular activities (AAA); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 429622 [Multi-domain] Cd Length: 131 Bit Score: 41.39 E-value: 2.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 398 HVIIVGDPGLGKSQLLQAAAAisprgiyVCGNATTR---------AGLTVAVVKDSMTNDYAFEAGA----MVLADgglc 464
Cdd:pfam07726 1 HVLLEGVPGLAKTLLVRTLAR-------SLGLDFRRiqftpdllpSDITGTEVFDQKTREFEFRPGPvfanVLLAD---- 69
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1063708510 465 cidEFDKMTTEHQ-ALLEAMEQQCVSVakAGLVASLSARTSVIAAANPV 512
Cdd:pfam07726 70 ---EINRAPPKTQsALLEAMQERQVTI--DGETHPLPEPFFVLATQNPI 113
|
|
| Sms |
COG1066 |
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and ... |
399-428 |
4.59e-03 |
|
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and repair];
Pssm-ID: 440685 [Multi-domain] Cd Length: 453 Bit Score: 40.42 E-value: 4.59e-03
10 20 30
....*....|....*....|....*....|....
gi 1063708510 399 VIIVGDPGLGKSQL-LQAAAAISPRG---IYVCG 428
Cdd:COG1066 92 VLIGGEPGIGKSTLlLQVAARLAKKGgkvLYVSG 125
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
393-428 |
7.45e-03 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 39.05 E-value: 7.45e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1063708510 393 VRGDIhVIIVGDPGLGKSQL-LQAAAAISPRG---IYVCG 428
Cdd:cd01121 80 VPGSV-VLIGGDPGIGKSTLlLQVAARLAQRGgkvLYVSG 118
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
399-494 |
7.87e-03 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 38.78 E-value: 7.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063708510 399 VIIVGDPGLGKSQLLQAAAAISPRGIYV-CGNATTRAGLTVAVVKD------SMTNDYAFEAGAMVLAD-GGLCCIDEFD 470
Cdd:COG2842 53 GVVYGESGVGKTTAAREYANRNPNVIYVtASPSWTSKELLEELAEElgipapPGTIADLRDRILERLAGtGRLLIIDEAD 132
|
90 100
....*....|....*....|....*
gi 1063708510 471 KMTTEHQALLEAM-EQQCVSVAKAG 494
Cdd:COG2842 133 HLKPKALEELRDIhDETGVGVVLIG 157
|
|
| |
