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Conserved domains on  [gi|1063678409|ref|NP_001319363|]
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Vps52 / Sac2 family [Arabidopsis thaliana]

Protein Classification

VPS52 family protein( domain architecture ID 10514074)

VPS52 family protein such as yeast vacuolar protein sorting-associated protein 52(Vps52, also called Sac2), which is part of a multi subunit complex required for protein sorting at yeast late golgi.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Vps52 pfam04129
Vps52 / Sac2 family; Vps52 complexes with Vps53 and Vps54 to form a multi- subunit complex ...
 107-600 0e+00

Vps52 / Sac2 family; Vps52 complexes with Vps53 and Vps54 to form a multi- subunit complex involved in regulating membrane trafficking events.


:

Pssm-ID: 282044  Cd Length: 508  Bit Score: 670.71  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 107 DYIKESDKLVSLHDQIRDCNCILSQMETLLSGFQEEIGSISSDIKILQENSMDMGLRLKNRRVTESKLAKFVEDFIVPPK 186
Cdd:pfam04129   8 DYIKESSNIASLHNQIAACDSVLEQMEDMLTEFQSDLSNISSDIDFLQEKSNEMQLRLENRQAVESKLSPFVDDLIVPPE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 187 MIHVIVDGEVNEEYIKTLGILSKKLKFVETDQAVKSSKALKDVEPELEKLRQKAISKVYDFIVQKLIALRKPKTNIQILQ 266
Cdd:pfam04129  88 LIDDIIEGPVNEPFFATQLEILNKKLSNVLDQSFKSSKAPKDVDQLLDKLRNKAIEKIRRYIVQKIKTFRKPMTNYQIIQ 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 267 QsVFLKYKYIISFLKEHGKEVFMDVRAAYIDTMNKVLSAHFQSYIQAFEKLQLDIATS-NDLIGVDTRSTGLFSRSKEPL 345
Cdd:pfam04129 168 N-ALLKYKFIFPFLLDNNRSLALELRQAYIDTMNKIYLSYFRSYIRRLTKLQFEEIDTkDDLMGVETTAKGLFFSKPVSL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 346 KNRCAVFALGERIQIIK-EIDQPALIPHIAEASSLKYPYEVLFRSLHKLLMDTATSEYIFCEDFFGE-----QSIFYEIF 419
Cdd:pfam04129 247 KKRNTIFTIGKRGNILTmQLDAPILVPHIAENNTTKYYIEALFRSLHLALLDNATSEYLFLKEFFAVsgdqaEDIFEQIF 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 420 AGPFSVIYEHLDSVLSSCYDAIGLLLMIRIIHHHQLIMSRRRIPCLDSYLDKVNISLWPRFKTVFDLHIGSLRNANINTI 499
Cdd:pfam04129 327 GKTLSEATKYLEQLISDCYDAIGVLLSIRIINRLQLIAERRGVPALDSYLNSVLIQLWPRFQLVFDMHCESLRKANITTL 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 500 WEDDVHPHYIMRRYAEFTASFIHLNVEYGDGQLDINLERLRMAVDSLILKLAKLFPRPKQQMVFLINNYDMTIAVLKEAE 579
Cdd:pfam04129 407 VEPDTRPHYLTRRYAEFLSSFVTLSVTHPNEIVERLLNRLQREVEDFILRLAKCFPKRKSQLRFLINNYDLLLGVLMELH 486

                         490       500
                  ....*....|....*....|.
gi 1063678409 580 PEGGKIQMHFEELLKSNTSLF 600
Cdd:pfam04129 487 LDLSKEQEDFQEYLNSNTENF 507
 
Name Accession Description Interval E-value
Vps52 pfam04129
Vps52 / Sac2 family; Vps52 complexes with Vps53 and Vps54 to form a multi- subunit complex ...
 107-600 0e+00

Vps52 / Sac2 family; Vps52 complexes with Vps53 and Vps54 to form a multi- subunit complex involved in regulating membrane trafficking events.


Pssm-ID: 282044  Cd Length: 508  Bit Score: 670.71  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 107 DYIKESDKLVSLHDQIRDCNCILSQMETLLSGFQEEIGSISSDIKILQENSMDMGLRLKNRRVTESKLAKFVEDFIVPPK 186
Cdd:pfam04129   8 DYIKESSNIASLHNQIAACDSVLEQMEDMLTEFQSDLSNISSDIDFLQEKSNEMQLRLENRQAVESKLSPFVDDLIVPPE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 187 MIHVIVDGEVNEEYIKTLGILSKKLKFVETDQAVKSSKALKDVEPELEKLRQKAISKVYDFIVQKLIALRKPKTNIQILQ 266
Cdd:pfam04129  88 LIDDIIEGPVNEPFFATQLEILNKKLSNVLDQSFKSSKAPKDVDQLLDKLRNKAIEKIRRYIVQKIKTFRKPMTNYQIIQ 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 267 QsVFLKYKYIISFLKEHGKEVFMDVRAAYIDTMNKVLSAHFQSYIQAFEKLQLDIATS-NDLIGVDTRSTGLFSRSKEPL 345
Cdd:pfam04129 168 N-ALLKYKFIFPFLLDNNRSLALELRQAYIDTMNKIYLSYFRSYIRRLTKLQFEEIDTkDDLMGVETTAKGLFFSKPVSL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 346 KNRCAVFALGERIQIIK-EIDQPALIPHIAEASSLKYPYEVLFRSLHKLLMDTATSEYIFCEDFFGE-----QSIFYEIF 419
Cdd:pfam04129 247 KKRNTIFTIGKRGNILTmQLDAPILVPHIAENNTTKYYIEALFRSLHLALLDNATSEYLFLKEFFAVsgdqaEDIFEQIF 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 420 AGPFSVIYEHLDSVLSSCYDAIGLLLMIRIIHHHQLIMSRRRIPCLDSYLDKVNISLWPRFKTVFDLHIGSLRNANINTI 499
Cdd:pfam04129 327 GKTLSEATKYLEQLISDCYDAIGVLLSIRIINRLQLIAERRGVPALDSYLNSVLIQLWPRFQLVFDMHCESLRKANITTL 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 500 WEDDVHPHYIMRRYAEFTASFIHLNVEYGDGQLDINLERLRMAVDSLILKLAKLFPRPKQQMVFLINNYDMTIAVLKEAE 579
Cdd:pfam04129 407 VEPDTRPHYLTRRYAEFLSSFVTLSVTHPNEIVERLLNRLQREVEDFILRLAKCFPKRKSQLRFLINNYDLLLGVLMELH 486

                         490       500
                  ....*....|....*....|.
gi 1063678409 580 PEGGKIQMHFEELLKSNTSLF 600
Cdd:pfam04129 487 LDLSKEQEDFQEYLNSNTENF 507
 
Name Accession Description Interval E-value
Vps52 pfam04129
Vps52 / Sac2 family; Vps52 complexes with Vps53 and Vps54 to form a multi- subunit complex ...
 107-600 0e+00

Vps52 / Sac2 family; Vps52 complexes with Vps53 and Vps54 to form a multi- subunit complex involved in regulating membrane trafficking events.


Pssm-ID: 282044  Cd Length: 508  Bit Score: 670.71  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 107 DYIKESDKLVSLHDQIRDCNCILSQMETLLSGFQEEIGSISSDIKILQENSMDMGLRLKNRRVTESKLAKFVEDFIVPPK 186
Cdd:pfam04129   8 DYIKESSNIASLHNQIAACDSVLEQMEDMLTEFQSDLSNISSDIDFLQEKSNEMQLRLENRQAVESKLSPFVDDLIVPPE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 187 MIHVIVDGEVNEEYIKTLGILSKKLKFVETDQAVKSSKALKDVEPELEKLRQKAISKVYDFIVQKLIALRKPKTNIQILQ 266
Cdd:pfam04129  88 LIDDIIEGPVNEPFFATQLEILNKKLSNVLDQSFKSSKAPKDVDQLLDKLRNKAIEKIRRYIVQKIKTFRKPMTNYQIIQ 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 267 QsVFLKYKYIISFLKEHGKEVFMDVRAAYIDTMNKVLSAHFQSYIQAFEKLQLDIATS-NDLIGVDTRSTGLFSRSKEPL 345
Cdd:pfam04129 168 N-ALLKYKFIFPFLLDNNRSLALELRQAYIDTMNKIYLSYFRSYIRRLTKLQFEEIDTkDDLMGVETTAKGLFFSKPVSL 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 346 KNRCAVFALGERIQIIK-EIDQPALIPHIAEASSLKYPYEVLFRSLHKLLMDTATSEYIFCEDFFGE-----QSIFYEIF 419
Cdd:pfam04129 247 KKRNTIFTIGKRGNILTmQLDAPILVPHIAENNTTKYYIEALFRSLHLALLDNATSEYLFLKEFFAVsgdqaEDIFEQIF 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 420 AGPFSVIYEHLDSVLSSCYDAIGLLLMIRIIHHHQLIMSRRRIPCLDSYLDKVNISLWPRFKTVFDLHIGSLRNANINTI 499
Cdd:pfam04129 327 GKTLSEATKYLEQLISDCYDAIGVLLSIRIINRLQLIAERRGVPALDSYLNSVLIQLWPRFQLVFDMHCESLRKANITTL 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 500 WEDDVHPHYIMRRYAEFTASFIHLNVEYGDGQLDINLERLRMAVDSLILKLAKLFPRPKQQMVFLINNYDMTIAVLKEAE 579
Cdd:pfam04129 407 VEPDTRPHYLTRRYAEFLSSFVTLSVTHPNEIVERLLNRLQREVEDFILRLAKCFPKRKSQLRFLINNYDLLLGVLMELH 486

                         490       500
                  ....*....|....*....|.
gi 1063678409 580 PEGGKIQMHFEELLKSNTSLF 600
Cdd:pfam04129 487 LDLSKEQEDFQEYLNSNTENF 507
Sec3_C pfam09763
Exocyst complex component Sec3; This entry is the conserved middle and C-terminus of the Sec3 ...
 78-414 6.31e-03

Exocyst complex component Sec3; This entry is the conserved middle and C-terminus of the Sec3 protein. Sec3 binds to the C-terminal cytoplasmic domain of GLYT1 (glycine transporter protein 1). Sec3 is the exocyst component that is closest to the plasma membrane docking site and it serves as a spatial landmark in the plasma membrane for incoming secretory vesicles. Sec3 is recruited to the sites of polarised membrane growth through its interaction with Rho1p, a small GTP-binding protein.


Pssm-ID: 401638  Cd Length: 696  Bit Score: 40.01  E-value: 6.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409  78 DKLREYAKGVENNLRKVELDSVeVAILlpdyikESDKLVS-LHDQIRDCNCILSQMETLLSGFQEEIGSISSDIKILQEN 156
Cdd:pfam09763   1 DDADVLEERLSRELSKLEYANI-KSLL------ESDKRVNeLMKHIDKALKECDELDPTLTLYSMELSTLSDDIEYIESQ 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 157 SMDMGLRLKNRRVTESKLAKFVEDFIVPPKMIHVIVDGEVN-----EEYIKTLGILSKKLKFVETDQAVKSS-----KAL 226
Cdd:pfam09763  74 NNGLQVQSANQKLLYKELESLLNTVSLPESDLHALLEGPLSspnglEALEAALVALFKALNAIDGDKKDLDSdlgdmRAL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 227 KDVEPELEKLRQKAISKVYDFI-----------VQKLIALRKPKTNIQILQQ--SVFLKYKYIISFLKEHGKEVFMDVRA 293
Cdd:pfam09763 154 KERRARYEKVTSLFLKRLVDFLnnrfknafkslGSDLDSATSNELSLPNHLNvlNNLLIYSGLMLFLKEVDPETYEALLQ 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678409 294 AYIDTMNKVLSAHFQSyiqAFEKLQLDIATSNDLIGVDTRST-GLFSRSKEPLKNRCAVFALGERIQIIKEIDQPAlipH 372
Cdd:pfam09763 234 LYNASASKIYEREFKD---FFEYLKKQLKKSSGSEESESLFSsGQDELYTEWLALRKSRKLTLDSSKTGANLSTKA---P 307

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 1063678409 373 IAEASSLKYPYEVLFRSLHKLLmDTATSEYIFCEDFFGEQSI 414
Cdd:pfam09763 308 QSKLSGRLRPDEAFAGALDELE-PLILVEQNFIIDFFHLSSL 348
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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