|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
14-206 |
1.89e-85 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 249.86 E-value: 1.89e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADN 93
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFRLPIYGNLSWDDIPNYLPDDSKVFLADN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 94 cglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetgasqdwlpHVEVQSYDS-DWTEAPAAVVIGGETYGVSLESLQ 172
Cdd:cd18106 81 ----------------------------------------------NLPVQPYDSiDYCSGPIVLVIGGETHGVSPEAYK 114
|
170 180 190
....*....|....*....|....*....|....
gi 962608812 173 LAESTGGKRLLIPVVPGVDSLNSAMAASILLFEG 206
Cdd:cd18106 115 LAHSTGGSRVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
13-213 |
5.98e-39 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 135.32 E-value: 5.98e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 13 PLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPII--NNLEwetvpnylppdtrvyv 90
Cdd:COG0566 115 PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVArvTNLA---------------- 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 91 adncglyaqaemsnkasdhgwvcdqRVMKFHKyeeEEDVET-GASqdwlPHVEVQSYDSDWTEaPAAVVIGGETYGVSLE 169
Cdd:COG0566 179 -------------------------DALEELK---EAGFWVvGTD----LDGEASLYEVDLPG-PVALVLGNEGKGLSRL 225
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 962608812 170 SLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRGR 213
Cdd:COG0566 226 VLEACD----ELVRIPMAGGVESLNVAVAAAILLYEAARQRRAK 265
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
13-204 |
5.24e-28 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 103.38 E-value: 5.24e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 13 PLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAWEPKVLRAGMGAHFRMPII--NNLEwETVPNYLPPDTRVY 89
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEpRSADPYNPKAIRASAGALFHLPLVvvDNLE-EALKDLKEAGYAVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 90 VADncglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetGASQDWlphvevqsYDSDWTEaPAAVVIGGETYGVSLE 169
Cdd:pfam00588 80 ATS---------------------------------------LGGKSL--------YEIDFPK-KVALVFGNEGTGLSNE 111
|
170 180 190
....*....|....*....|....*....|....*
gi 962608812 170 SLQLAEstggKRLLIPVVPGVDSLNSAMAASILLF 204
Cdd:pfam00588 112 VLELCD----RLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
4-210 |
1.31e-16 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 75.84 E-value: 1.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 4 PKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIInnleweTVPNYlp 83
Cdd:TIGR00186 81 YKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLA------RVTNL-- 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 84 pdtrvyvadncglyaqAEMSNKASDHG-WVcdqrvmkfhkyeeeedVETGASQDWlphvevQSYDSDWTEaPAAVVIGGE 162
Cdd:TIGR00186 153 ----------------SRTITKLKESGfWT----------------VGTDLDAQD------TLYQVKLTK-PLALVVGNE 193
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 962608812 163 TYGVSLESLQLAEStggkRLLIPVVPGVDSLNSAMAASILLFEGKRQL 210
Cdd:TIGR00186 194 GEGVSRLIKENCDF----LIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
149-209 |
1.27e-07 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 50.38 E-value: 1.27e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 962608812 149 DWTEaPAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 209
Cdd:PRK11081 109 DYTR-PTCILMGQEKTGISQEALALAD----QDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
14-206 |
1.89e-85 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 249.86 E-value: 1.89e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADN 93
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCVDPWEPKVLRAGAGAHFRLPIYGNLSWDDIPNYLPDDSKVFLADN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 94 cglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetgasqdwlpHVEVQSYDS-DWTEAPAAVVIGGETYGVSLESLQ 172
Cdd:cd18106 81 ----------------------------------------------NLPVQPYDSiDYCSGPIVLVIGGETHGVSPEAYK 114
|
170 180 190
....*....|....*....|....*....|....
gi 962608812 173 LAESTGGKRLLIPVVPGVDSLNSAMAASILLFEG 206
Cdd:cd18106 115 LAHSTGGSRVHIPLANGVDSLNSAVAASILLFEM 148
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
14-205 |
3.92e-46 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 149.88 E-value: 3.92e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPP-DTRVYVAD 92
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEaGYKVVAAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 93 ncglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetgasqdwlPHVEVQSYDSDWTEaPAAVVIGGETYGVSLESLQ 172
Cdd:cd18095 81 ----------------------------------------------LDGGSSLYDLDLPK-PVALVLGNEGNGLSDELLE 113
|
170 180 190
....*....|....*....|....*....|...
gi 962608812 173 LAEstggKRLLIPVVPGVDSLNSAMAASILLFE 205
Cdd:cd18095 114 LCD----KRVTIPMSGGVESLNVAVAAAILLYE 142
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
13-213 |
5.98e-39 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 135.32 E-value: 5.98e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 13 PLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPII--NNLEwetvpnylppdtrvyv 90
Cdd:COG0566 115 PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVArvTNLA---------------- 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 91 adncglyaqaemsnkasdhgwvcdqRVMKFHKyeeEEDVET-GASqdwlPHVEVQSYDSDWTEaPAAVVIGGETYGVSLE 169
Cdd:COG0566 179 -------------------------DALEELK---EAGFWVvGTD----LDGEASLYEVDLPG-PVALVLGNEGKGLSRL 225
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 962608812 170 SLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRGR 213
Cdd:COG0566 226 VLEACD----ELVRIPMAGGVESLNVAVAAAILLYEAARQRRAK 265
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
14-209 |
1.18e-28 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 104.97 E-value: 1.18e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVpNYLppdtrvyvadn 93
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVAEASSEETL-AWL----------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 94 cglyaqaemsnkasdhgwvcdqrvmKFHKYeeeedvETGASqdwLPHVEVQSYDSDWTeAPAAVVIGGETYGVSLESLQL 173
Cdd:cd18104 69 -------------------------KENKI------RILAT---TPKAEKLYYEADLR-GPIAIVVGSESEGLSEFWLKA 113
|
170 180 190
....*....|....*....|....*....|....*.
gi 962608812 174 AestgGKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 209
Cdd:cd18104 114 A----DERVRIPMAGQADSLNVSVAAAILLYEALRQ 145
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
13-204 |
5.24e-28 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 103.38 E-value: 5.24e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 13 PLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAWEPKVLRAGMGAHFRMPII--NNLEwETVPNYLPPDTRVY 89
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEpRSADPYNPKAIRASAGALFHLPLVvvDNLE-EALKDLKEAGYAVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 90 VADncglyaqaemsnkasdhgwvcdqrvmkfhkyeeeedvetGASQDWlphvevqsYDSDWTEaPAAVVIGGETYGVSLE 169
Cdd:pfam00588 80 ATS---------------------------------------LGGKSL--------YEIDFPK-KVALVFGNEGTGLSNE 111
|
170 180 190
....*....|....*....|....*....|....*
gi 962608812 170 SLQLAEstggKRLLIPVVPGVDSLNSAMAASILLF 204
Cdd:pfam00588 112 VLELCD----RLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
14-205 |
9.17e-27 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 99.92 E-value: 9.17e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNyLPPDTRVYVADn 93
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIICSPDTVDPYNPKVVQASMGSIFRVQIHYTDLPALLAE-LKKAFPVYGAD- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 94 cglyaqaeMsnkasdHGwvcdqrvmkfhkyeeeEDVetgasqdwlphvevqsYDSDWTEaPAAVVIGGETYGVSLESLQL 173
Cdd:cd18109 79 --------L------DG----------------ENL----------------YEFTLPE-KGILVMGNEGHGISPEVLKL 111
|
170 180 190
....*....|....*....|....*....|...
gi 962608812 174 AEstggKRLLIPVVP-GVDSLNSAMAASILLFE 205
Cdd:cd18109 112 LT----HRLTIPRYGkGAESLNVAVATAILLSE 140
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
16-205 |
3.82e-24 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 93.44 E-value: 3.82e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 16 LICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPiinnleWETVPNYLpPDTRVYVADNCG 95
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVP------YERVDNFE-EYLKSLKEEGYP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 96 LYAqaemsnkasdhgwvcdqrvmkfhkyeeeedVETGASQDWLPHVEVQsydsdwTEAPAAVVIGGETYGVSLESLQLAE 175
Cdd:cd18082 75 LIG------------------------------LELTDGSIPLSEFKFK------KPKKIALIFGNERSGLSPELLALCD 118
|
170 180 190
....*....|....*....|....*....|
gi 962608812 176 stggKRLLIPVVPGVDSLNSAMAASILLFE 205
Cdd:cd18082 119 ----YTVHIPMSGKNSSLNVSVATGIALYE 144
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
14-205 |
3.02e-18 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 77.81 E-value: 3.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTK-GCVDAwEPKVLRAGMGAHFRMPII--NNLEwETVpnylppdtrvyv 90
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKrRSAPL-TPTVAKASAGALEHLPIArvTNLA-RAL------------ 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 91 adncglyaqaemsNKASDHG-WV--CDQrvmkfhkyEEEEDVetgasqdwlphvevqsYDSDWTEaPAAVVIGGETYGVS 167
Cdd:cd18103 67 -------------EELKEAGfWIygADG--------EAEKSL----------------YDVDLTG-PLALVLGSEGKGLR 108
|
170 180 190
....*....|....*....|....*....|....*...
gi 962608812 168 LESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFE 205
Cdd:cd18103 109 RLVLKNCD----FLVKIPMAGKVDSLNVSVAAGIILYE 142
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
14-205 |
3.78e-17 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 75.12 E-value: 3.78e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINnlewetVPnylppdtrvyvadn 93
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVR------VP-------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 94 cglyAQAEMSNkasdhgWVCDQRVmkfhKYEEEEDVETGAsqdwlpHVEVQSYDSDWTeAPAAVVIGGETYGVSLESLQL 173
Cdd:cd18107 61 ----SNRELED------WVEARKA----RGTPLQLVGTDE------HGDHQIADHDFT-RPTLLLIGNETAGLSAAWREL 119
|
170 180 190
....*....|....*....|....*....|..
gi 962608812 174 AESTGGkrllIPVVPGVDSLNSAMAASILLFE 205
Cdd:cd18107 120 CDETVS----IPMAGSASSLNAACAASIFLYE 147
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
4-210 |
1.31e-16 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 75.84 E-value: 1.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 4 PKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIInnleweTVPNYlp 83
Cdd:TIGR00186 81 YKTAKSKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLA------RVTNL-- 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 84 pdtrvyvadncglyaqAEMSNKASDHG-WVcdqrvmkfhkyeeeedVETGASQDWlphvevQSYDSDWTEaPAAVVIGGE 162
Cdd:TIGR00186 153 ----------------SRTITKLKESGfWT----------------VGTDLDAQD------TLYQVKLTK-PLALVVGNE 193
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 962608812 163 TYGVSLESLQLAEStggkRLLIPVVPGVDSLNSAMAASILLFEGKRQL 210
Cdd:TIGR00186 194 GEGVSRLIKENCDF----LIKIPMAGKVDSLNVSVAAGILLFEIKRQR 237
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
14-205 |
2.37e-13 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 64.89 E-value: 2.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPiinnleWETVPNYLPPdTRVYVADN 93
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTADAAGVEKIYLCGYTPTPPHPKVAKTALGAEESVP------WEHFEDTLEA-VRALKARG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 94 CGLYAqaemsnkasdhgwvcdqrvmkfhkyeeeedVETGA-SQDWlphvevqsYDSDWtEAPAAVVIGGETYGVSLESLQ 172
Cdd:cd18097 74 YTIIA------------------------------LETTEnSVPL--------HEARL-PRPLALVLGNEVRGVSPEVLA 114
|
170 180 190
....*....|....*....|....*....|...
gi 962608812 173 LAESTggkrLLIPVVPGVDSLNSAMAASILLFE 205
Cdd:cd18097 115 LCDAV----VEIPMFGRKNSLNVAVAAAVALYE 143
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
14-203 |
3.28e-13 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 64.85 E-value: 3.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 14 LLLicDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPI--INNLewetvpnylppdtrvyva 91
Cdd:cd18105 3 LLL--DEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIysVDNL------------------ 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 92 dncglyaqAEMSNKASDHGW-----VCDQRVMKFHKYeeeedvetgasqdwlphVEVQSYDSDWTEAPAAVVIGGETYGV 166
Cdd:cd18105 63 --------ASFLKSSKENGWkvvgtSAPPSASSDKKT-----------------IPANELSELLLEKPTILVLGNEGRGL 117
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 962608812 167 SLESLQLAESTggkrLLIPV-----VPGVDSLNSAMAASILL 203
Cdd:cd18105 118 RTNIKNLCDYL----VSIPGgrsaeNPGVDSLNVSVAAGILL 155
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
149-209 |
1.27e-07 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 50.38 E-value: 1.27e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 962608812 149 DWTEaPAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 209
Cdd:PRK11081 109 DYTR-PTCILMGQEKTGISQEALALAD----QDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
146-210 |
6.78e-07 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 47.46 E-value: 6.78e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 962608812 146 YDSDWTEaPAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 210
Cdd:cd18092 103 DELDYTR-PTALVFGNEKDGVSEEALAAAD----ERVYIPMYGFVESLNVSVAAAIILYELQRQR 162
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
139-210 |
5.36e-06 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 44.75 E-value: 5.36e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 962608812 139 PHVEVQSYDSDWteapaaVVIGGETYGVSLEslqLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 210
Cdd:cd18094 83 PYTDFDFKPGDY------LVFGRESTGLPEE---ILDAFPDRRLRIPMRPKVRSLNLSNSVAIVLYEALRQL 145
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
139-210 |
1.26e-05 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 43.87 E-value: 1.26e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 962608812 139 PHVEVQSYDSDWteapaaVVIGGETYGVSLEslqLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQL 210
Cdd:COG0219 85 PYTDVDYQPGDV------LLFGRETAGLPEE---VLAAPADQRLRIPMRPGVRSLNLSNAVAIVLYEALRQL 147
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
9-209 |
1.32e-05 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 44.57 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 9 QHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHfrmpiinnlewETVPNYlppdtRV 88
Cdd:PRK11181 91 SLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAA-----------ETVPLI-----RV 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 962608812 89 yvadncglyaqaemSNKAsdhgwvcdqRVMKFHKYEEEEDVETGASQDwlpHvevQSYDSDWTeAPAAVVIGgetygvsl 168
Cdd:PRK11181 155 --------------TNLA---------RTMRMLQEKNIWIVGTAGEAD---H---TLYQSKLT-GPLALVMG-------- 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 962608812 169 eslqlAESTGGKRLL---------IPVVPGVDSLNSAMAASILLFEGKRQ 209
Cdd:PRK11181 197 -----AEGEGMRRLTrehcdelisIPMAGSVSSLNVSVATGICLFEAVRQ 241
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
154-205 |
8.96e-03 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 35.55 E-value: 8.96e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 962608812 154 PAAVVIGGETYGVSLESLQLAEstggKRLLIPVVPGVDSLNSAMAASILLFE 205
Cdd:cd18093 105 KVALVFGREDSGLTNEELALCD----LLVTIPTNPEYPSLNLAQAVAIVLYE 152
|
|
| |
