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Conserved domains on  [gi|758818571|ref|NP_001292016|]
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alpha/beta-tubulin-N-acetyltransferase 9 isoform 11 [Homo sapiens]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 12134272)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.1.-
Gene Ontology:  GO:0008080
PubMed:  9175471|10940244|15581578
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 2-107 1.31e-09

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


:

Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 51.96  E-value: 1.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818571    2 GYHEWMKSEELQRLTASEPLTLEQEYA-MQCSWQEDADK--CTFIVLDAEkwqaqpgateeSCMVGDVNLFLTDLEDLTL 78
Cdd:pfam13302  14 ALFELLSDPEVMRYGVPWPLTLEEAREwLARIWAADEAErgYGWAIELKD-----------TGFIGSIGLYDIDGEPERA 82

                          90       100
                  ....*....|....*....|....*....
gi 758818571   79 gEIEVMIAePSCRGKGLGTEAVLAMLSYG 107
Cdd:pfam13302  83 -ELGYWLG-PDYWGKGYATEAVRALLEYA 109
 
Name Accession Description Interval E-value
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 2-107 1.31e-09

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 51.96  E-value: 1.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818571    2 GYHEWMKSEELQRLTASEPLTLEQEYA-MQCSWQEDADK--CTFIVLDAEkwqaqpgateeSCMVGDVNLFLTDLEDLTL 78
Cdd:pfam13302  14 ALFELLSDPEVMRYGVPWPLTLEEAREwLARIWAADEAErgYGWAIELKD-----------TGFIGSIGLYDIDGEPERA 82

                          90       100
                  ....*....|....*....|....*....
gi 758818571   79 gEIEVMIAePSCRGKGLGTEAVLAMLSYG 107
Cdd:pfam13302  83 -ELGYWLG-PDYWGKGYATEAVRALLEYA 109
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 3-107 3.15e-08

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 48.84  E-value: 3.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818571   3 YHEWMKSEELQRLTASEPLTLEQEYAMQCSWQEDADKCTFIVLDAEKwqaqpgaTEESCMVGDVNLFLTDLEDLTlGEIE 82
Cdd:COG1670   21 LAELLNDPEVARYLPGPPYSLEEARAWLERLLADWADGGALPFAIED-------KEDGELIGVVGLYDIDRANRS-AEIG 92

                         90       100
                 ....*....|....*....|....*
gi 758818571  83 VMIAePSCRGKGLGTEAVLAMLSYG 107
Cdd:COG1670   93 YWLA-PAYWGKGYATEALRALLDYA 116
 
Name Accession Description Interval E-value
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 2-107 1.31e-09

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 51.96  E-value: 1.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818571    2 GYHEWMKSEELQRLTASEPLTLEQEYA-MQCSWQEDADK--CTFIVLDAEkwqaqpgateeSCMVGDVNLFLTDLEDLTL 78
Cdd:pfam13302  14 ALFELLSDPEVMRYGVPWPLTLEEAREwLARIWAADEAErgYGWAIELKD-----------TGFIGSIGLYDIDGEPERA 82

                          90       100
                  ....*....|....*....|....*....
gi 758818571   79 gEIEVMIAePSCRGKGLGTEAVLAMLSYG 107
Cdd:pfam13302  83 -ELGYWLG-PDYWGKGYATEAVRALLEYA 109
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 3-107 3.15e-08

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 48.84  E-value: 3.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 758818571   3 YHEWMKSEELQRLTASEPLTLEQEYAMQCSWQEDADKCTFIVLDAEKwqaqpgaTEESCMVGDVNLFLTDLEDLTlGEIE 82
Cdd:COG1670   21 LAELLNDPEVARYLPGPPYSLEEARAWLERLLADWADGGALPFAIED-------KEDGELIGVVGLYDIDRANRS-AEIG 92

                         90       100
                 ....*....|....*....|....*
gi 758818571  83 VMIAePSCRGKGLGTEAVLAMLSYG 107
Cdd:COG1670   93 YWLA-PAYWGKGYATEALRALLDYA 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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