NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|665393402|ref|NP_001287206|]
View 

uncharacterized protein Dmel_CG10053, isoform B [Drosophila melanogaster]

Protein Classification

G patch domain-containing protein( domain architecture ID 10482052)

G patch domain-containing protein similar to Saccharomyces cerevisiae protein YLR271W

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF4187 pfam13821
Domain of unknown function (DUF4187); This family is found at the very C-terminus of proteins ...
 221-266 1.86e-22

Domain of unknown function (DUF4187); This family is found at the very C-terminus of proteins that carry a G-patch domain, pfam01585. The domain is short and cysteine-rich.


:

Pssm-ID: 463989  Cd Length: 50  Bit Score: 87.24  E-value: 1.86e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 665393402  221 YSPSEQLELLTGYLRTAYCFCYWCGTHYDDAEDLGSNCPGLTRDEH 266
Cdd:pfam13821   5 LEPEERLEKLLSYLREEYNYCFWCGTQYEDEEDLEENCPGLTEEDH 50
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 73-116 1.70e-13

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


:

Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 63.30  E-value: 1.70e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 665393402   73 DNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLGRE 116
Cdd:pfam01585   2 SNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLGAE 45
 
Name Accession Description Interval E-value
DUF4187 pfam13821
Domain of unknown function (DUF4187); This family is found at the very C-terminus of proteins ...
 221-266 1.86e-22

Domain of unknown function (DUF4187); This family is found at the very C-terminus of proteins that carry a G-patch domain, pfam01585. The domain is short and cysteine-rich.


Pssm-ID: 463989  Cd Length: 50  Bit Score: 87.24  E-value: 1.86e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 665393402  221 YSPSEQLELLTGYLRTAYCFCYWCGTHYDDAEDLGSNCPGLTRDEH 266
Cdd:pfam13821   5 LEPEERLEKLLSYLREEYNYCFWCGTQYEDEEDLEENCPGLTEEDH 50
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 73-116 1.70e-13

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 63.30  E-value: 1.70e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 665393402   73 DNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLGRE 116
Cdd:pfam01585   2 SNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLGAE 45
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 70-114 8.60e-11

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 56.01  E-value: 8.60e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 665393402    70 ISADNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLG 114
Cdd:smart00443   1 ISTSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLG 45
 
Name Accession Description Interval E-value
DUF4187 pfam13821
Domain of unknown function (DUF4187); This family is found at the very C-terminus of proteins ...
 221-266 1.86e-22

Domain of unknown function (DUF4187); This family is found at the very C-terminus of proteins that carry a G-patch domain, pfam01585. The domain is short and cysteine-rich.


Pssm-ID: 463989  Cd Length: 50  Bit Score: 87.24  E-value: 1.86e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 665393402  221 YSPSEQLELLTGYLRTAYCFCYWCGTHYDDAEDLGSNCPGLTRDEH 266
Cdd:pfam13821   5 LEPEERLEKLLSYLREEYNYCFWCGTQYEDEEDLEENCPGLTEEDH 50
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 73-116 1.70e-13

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 63.30  E-value: 1.70e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 665393402   73 DNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLGRE 116
Cdd:pfam01585   2 SNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLGAE 45
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 70-114 8.60e-11

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 56.01  E-value: 8.60e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 665393402    70 ISADNKGFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLG 114
Cdd:smart00443   1 ISTSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLG 45
G-patch_2 pfam12656
G-patch domain; Yeast Spp2, a G-patch protein and spliceosome component, interacts with the ...
 76-114 2.21e-03

G-patch domain; Yeast Spp2, a G-patch protein and spliceosome component, interacts with the ATP-dependent DExH-box splicing factor Prp2. As this interaction involves the G-patch sequence in Spp2 and is required for the recruitment of Prp2 to the spliceosome before the first catalytic step of splicing, it is proposed that Spp2 might be an accessory factor that confers spliceosome specificity on Prp2.


Pssm-ID: 432700 [Multi-domain]  Cd Length: 61  Bit Score: 35.72  E-value: 2.21e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 665393402   76 GFQLLAKMGYKAGSGLGITSDARTEPVGITIKSGRGGLG 114
Cdd:pfam12656  18 GAAMLRGMGWKPGQGIGKNKKGDVKPKEYKRRPGGLGLG 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH