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Conserved domains on  [gi|1834199339|ref|NP_001261221|]
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uncharacterized protein Dmel_CG13896, isoform E [Drosophila melanogaster]

Protein Classification

myb/SANT-like DNA-binding domain-containing protein( domain architecture ID 10619758)

nyb/SANT (SWI3, ADA2, N-CoR and TFIIIB)-like DNA-binding domain-containing protein may bind DNA and function as a transcription factor

CATH:  1.20.58.1880
Gene Ontology:  GO:0003700|GO:0003677
PubMed:  8882580
SCOP:  4000317

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Myb_DNA-bind_4 pfam13837
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb ...
 7-94 4.30e-11

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT-like DNA binding domains. In particular pfam10545 seems most related. This family is greatly expanded in plants and appears in several proteins annotated as transposon proteins.


:

Pssm-ID: 463994  Cd Length: 84  Bit Score: 57.66  E-value: 4.30e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199339   7 ERKWCTSNTRLLLSLYNERQAD-FRDPKKKIKDIWGEMVVALESQGMtDIDAVQLDRKFRNLKKTYYSIRSKLLAKVPHf 85
Cdd:pfam13837   1 RNKWTEEETLALIEIWGERLELrFQESKKRNKKLWEEIAEKMAELGY-NRSPEQCKEKWENLKKKYRKEKEGNNGSGSS- 78


                  ....*....
gi 1834199339  86 hpnWQFYDE 94
Cdd:pfam13837  79 ---WPFFEE 84
 
Name Accession Description Interval E-value
Myb_DNA-bind_4 pfam13837
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb ...
 7-94 4.30e-11

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT-like DNA binding domains. In particular pfam10545 seems most related. This family is greatly expanded in plants and appears in several proteins annotated as transposon proteins.


Pssm-ID: 463994  Cd Length: 84  Bit Score: 57.66  E-value: 4.30e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199339   7 ERKWCTSNTRLLLSLYNERQAD-FRDPKKKIKDIWGEMVVALESQGMtDIDAVQLDRKFRNLKKTYYSIRSKLLAKVPHf 85
Cdd:pfam13837   1 RNKWTEEETLALIEIWGERLELrFQESKKRNKKLWEEIAEKMAELGY-NRSPEQCKEKWENLKKKYRKEKEGNNGSGSS- 78


                  ....*....
gi 1834199339  86 hpnWQFYDE 94
Cdd:pfam13837  79 ---WPFFEE 84
 
Name Accession Description Interval E-value
Myb_DNA-bind_4 pfam13837
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb ...
 7-94 4.30e-11

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT-like DNA binding domains. In particular pfam10545 seems most related. This family is greatly expanded in plants and appears in several proteins annotated as transposon proteins.


Pssm-ID: 463994  Cd Length: 84  Bit Score: 57.66  E-value: 4.30e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199339   7 ERKWCTSNTRLLLSLYNERQAD-FRDPKKKIKDIWGEMVVALESQGMtDIDAVQLDRKFRNLKKTYYSIRSKLLAKVPHf 85
Cdd:pfam13837   1 RNKWTEEETLALIEIWGERLELrFQESKKRNKKLWEEIAEKMAELGY-NRSPEQCKEKWENLKKKYRKEKEGNNGSGSS- 78


                  ....*....
gi 1834199339  86 hpnWQFYDE 94
Cdd:pfam13837  79 ---WPFFEE 84
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 6-96 4.27e-04

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 38.04  E-value: 4.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199339   6 YERKWCtsntrlllsLYNERQADFRDPKKKIKdIWGEMVVALESqgmtDIDAVQLDRKFRNLKKTYYS-IRSKLLAKVPH 84
Cdd:pfam10545   5 VREHPC---------LWDRSHPDYRNRDARER-AWEEIAEELGS----DVPVEDCKKRWKNLRDQYRReLRRKRTNSGEL 70

                          90
                  ....*....|..
gi 1834199339  85 FHPNWQFYDEMS 96
Cdd:pfam10545  71 YKSRWYYYEELS 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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