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Conserved domains on  [gi|442627608|ref|NP_001260413|]
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uncharacterized protein Dmel_CG5446, isoform B [Drosophila melanogaster]

Protein Classification

heat shock factor-binding 1 family protein( domain architecture ID 10536259)

heat shock factor-binding 1 (HSBP1) family protein similar to human HSBP1, a regulator of heat shock response that negatively affects HSF1 DNA-binding activity and may have a role in the suppression of the activation of the stress response during the aging process

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HSBP1 pfam06825
Heat shock factor binding protein 1; Heat shock factor binding protein 1 (HSBP1) appears to be ...
 28-72 1.16e-15

Heat shock factor binding protein 1; Heat shock factor binding protein 1 (HSBP1) appears to be a negative regulator of the heat shock response.


:

Pssm-ID: 429139  Cd Length: 51  Bit Score: 64.07  E-value: 1.16e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 442627608  28 QELTIY------NVQDKFQTMSDQIITRIDDMGNRIDDLEKSIADLMNQAG 72
Cdd:pfam06825  1 QELTAFvenllqQLQDKFQTMSDQILGRIDEMGSRIDDLEKSIADLMTQAG 51
 
Name Accession Description Interval E-value
HSBP1 pfam06825
Heat shock factor binding protein 1; Heat shock factor binding protein 1 (HSBP1) appears to be ...
 28-72 1.16e-15

Heat shock factor binding protein 1; Heat shock factor binding protein 1 (HSBP1) appears to be a negative regulator of the heat shock response.


Pssm-ID: 429139  Cd Length: 51  Bit Score: 64.07  E-value: 1.16e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 442627608  28 QELTIY------NVQDKFQTMSDQIITRIDDMGNRIDDLEKSIADLMNQAG 72
Cdd:pfam06825  1 QELTAFvenllqQLQDKFQTMSDQILGRIDEMGSRIDDLEKSIADLMTQAG 51
 
Name Accession Description Interval E-value
HSBP1 pfam06825
Heat shock factor binding protein 1; Heat shock factor binding protein 1 (HSBP1) appears to be ...
 28-72 1.16e-15

Heat shock factor binding protein 1; Heat shock factor binding protein 1 (HSBP1) appears to be a negative regulator of the heat shock response.


Pssm-ID: 429139  Cd Length: 51  Bit Score: 64.07  E-value: 1.16e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 442627608  28 QELTIY------NVQDKFQTMSDQIITRIDDMGNRIDDLEKSIADLMNQAG 72
Cdd:pfam06825  1 QELTAFvenllqQLQDKFQTMSDQILGRIDEMGSRIDDLEKSIADLMTQAG 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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