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Conserved domains on  [gi|386766727|ref|NP_001247361|]
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Glucosamine-phosphate N-acetyltransferase, isoform D [Drosophila melanogaster]

Protein Classification

GNAT family protein( domain architecture ID 106742)

GNAT (Gcn5-related N-acetyltransferase) family protein similar to N-acetyltransferases that catalyze the transfer of an acetyl group from acetyl-CoA to a substrate

PubMed:  15581578

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NAT_SF super family cl17182
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of ...
 43-174 2.52e-50

N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase which catalyze the transfer of an acetyl group to a substrate. The mechanism is an ordered Bi-Bi ternary complex kinetic mechanism for most GNATs: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and then CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/ph enylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


The actual alignment was detected with superfamily member PLN02706:

Pssm-ID: 473072 [Multi-domain]  Cd Length: 150  Bit Score: 160.64  E-value: 2.52e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  43 KVRPLKDTDYDRGFLQLLSQLTHVGNVNRTQFLTRFSQMKASGDY-FVTVIEDTRKNEIIGAASLVIERKFIHNCAVRGR 121
Cdd:PLN02706   8 KVRRLEISDKSKGFLELLQQLTVVGDVTEEEFEARFQELASLGDDhLICVIEDAASGRIIATGSVFVERKFIRNCGKVGH 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 386766727 122 LEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYESLGYV 174
Cdd:PLN02706  88 IEDVVVDSAARGKGLGKKIIEALTEHARSAGCYKVILDCSEENKAFYEKCGYV 140
 
Name Accession Description Interval E-value
PLN02706 PLN02706
glucosamine 6-phosphate N-acetyltransferase
 43-174 2.52e-50

glucosamine 6-phosphate N-acetyltransferase


Pssm-ID: 178308 [Multi-domain]  Cd Length: 150  Bit Score: 160.64  E-value: 2.52e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  43 KVRPLKDTDYDRGFLQLLSQLTHVGNVNRTQFLTRFSQMKASGDY-FVTVIEDTRKNEIIGAASLVIERKFIHNCAVRGR 121
Cdd:PLN02706   8 KVRRLEISDKSKGFLELLQQLTVVGDVTEEEFEARFQELASLGDDhLICVIEDAASGRIIATGSVFVERKFIRNCGKVGH 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 386766727 122 LEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYESLGYV 174
Cdd:PLN02706  88 IEDVVVDSAARGKGLGKKIIEALTEHARSAGCYKVILDCSEENKAFYEKCGYV 140
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 42-188 5.30e-10

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 55.38  E-value: 5.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  42 MKVRPLKDTDYDrGFLQLLSQLTHVgnvnrtqfltrfsqmKASGDYFVtVIEDtrkNEIIGAASLVIERKFIhncavrGR 121
Cdd:COG1246    1 MTIRPATPDDVP-AILELIRPYALE---------------EEIGEFWV-AEED---GEIVGCAALHPLDEDL------AE 54

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386766727 122 LEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYESLGYVAIPGNSNSMTIRYD 188
Cdd:COG1246   55 LRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSAAIHFYEKLGFEEIDKEDLPYAKVWQ 121
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 86-174 7.39e-09

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 51.30  E-value: 7.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727   86 DYFVTVIEDtrKNEIIGAASLVIERKFIHNCAVRgrledVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLI 165
Cdd:pfam13508   2 GGRFFVAED--DGKIVGFAALLPLDDEGALAELR-----LAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAA 74


                  ....*....
gi 386766727  166 KFYESLGYV 174
Cdd:pfam13508  75 AFYEKLGFE 83
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 91-159 1.29e-04

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 38.80  E-value: 1.29e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386766727  91 VIEDtrKNEIIGAASLVIERKFIHncavRGRLEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLD 159
Cdd:cd04301    3 VAED--DGEIVGFASLSPDGSGGD----TAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
 
Name Accession Description Interval E-value
PLN02706 PLN02706
glucosamine 6-phosphate N-acetyltransferase
 43-174 2.52e-50

glucosamine 6-phosphate N-acetyltransferase


Pssm-ID: 178308 [Multi-domain]  Cd Length: 150  Bit Score: 160.64  E-value: 2.52e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  43 KVRPLKDTDYDRGFLQLLSQLTHVGNVNRTQFLTRFSQMKASGDY-FVTVIEDTRKNEIIGAASLVIERKFIHNCAVRGR 121
Cdd:PLN02706   8 KVRRLEISDKSKGFLELLQQLTVVGDVTEEEFEARFQELASLGDDhLICVIEDAASGRIIATGSVFVERKFIRNCGKVGH 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 386766727 122 LEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYESLGYV 174
Cdd:PLN02706  88 IEDVVVDSAARGKGLGKKIIEALTEHARSAGCYKVILDCSEENKAFYEKCGYV 140
PTZ00330 PTZ00330
acetyltransferase; Provisional
 57-175 8.62e-18

acetyltransferase; Provisional


Pssm-ID: 140351 [Multi-domain]  Cd Length: 147  Bit Score: 76.80  E-value: 8.62e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  57 LQLLSQLTHVGNVNRTQfLTRFSQMKASGDYFVTVIEDTRKNEIIGAASLVIERKFIHNCAVRGRLEDVVVNDTYRGKQL 136
Cdd:PTZ00330  21 LELLSHLTSAPALSQEE-LEQIAARRRLAGVVTRVFVHSPTQRIVGTASLFVEPKFTRGGKCVGHIEDVVVDPSYRGQGL 99

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 386766727 137 GKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYESLGYVA 175
Cdd:PTZ00330 100 GRALISDLCEIARSSGCYKVILDCTEDMVAFYKKLGFRA 138
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 42-188 5.30e-10

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 55.38  E-value: 5.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  42 MKVRPLKDTDYDrGFLQLLSQLTHVgnvnrtqfltrfsqmKASGDYFVtVIEDtrkNEIIGAASLVIERKFIhncavrGR 121
Cdd:COG1246    1 MTIRPATPDDVP-AILELIRPYALE---------------EEIGEFWV-AEED---GEIVGCAALHPLDEDL------AE 54

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386766727 122 LEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYESLGYVAIPGNSNSMTIRYD 188
Cdd:COG1246   55 LRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSAAIHFYEKLGFEEIDKEDLPYAKVWQ 121
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 78-177 4.20e-09

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 53.13  E-value: 4.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  78 FSQMKASGDYFVTVIEDtrKNEIIGAASL-VIERKFIHncavrgrLEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKM 156
Cdd:COG0454   25 KAMEGSLAGAEFIAVDD--KGEPIGFAGLrRLDDKVLE-------LKRLYVLPEYRGKGIGKALLEALLEWARERGCTAL 95

                         90       100
                 ....*....|....*....|....
gi 386766727 157 SLDC---KDKLIKFYESLGYVAIP 177
Cdd:COG0454   96 ELDTldgNPAAIRFYERLGFKEIE 119
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 86-174 7.39e-09

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 51.30  E-value: 7.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727   86 DYFVTVIEDtrKNEIIGAASLVIERKFIHNCAVRgrledVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLI 165
Cdd:pfam13508   2 GGRFFVAED--DGKIVGFAALLPLDDEGALAELR-----LAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAA 74


                  ....*....
gi 386766727  166 KFYESLGYV 174
Cdd:pfam13508  75 AFYEKLGFE 83
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 85-173 8.56e-09

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 51.75  E-value: 8.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727   85 GDYFVTVIEDtrkNEIIGAASLVIERKFIHncavRGRLEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCK--- 161
Cdd:pfam00583  32 SEGFFVAEED---GELVGFASLSIIDDEPP----VGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCERIFLEVAadn 104

                          90
                  ....*....|..
gi 386766727  162 DKLIKFYESLGY 173
Cdd:pfam00583 105 LAAIALYEKLGF 116
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
44-177 4.09e-08

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 50.47  E-value: 4.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  44 VRPLKDTDYDRgflqlLSQLTHV--GNVNRTQFLTRFSQMKASGDYFVTVIEDtrknEIIGAASLviERKFIHNCAVRGR 121
Cdd:COG3153    1 IRPATPEDAEA-----IAALLRAafGPGREAELVDRLREDPAAGLSLVAEDDG----EIVGHVAL--SPVDIDGEGPALL 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 386766727 122 LEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYESLGYVAIP 177
Cdd:COG3153   70 LGPLAVDPEYRGQGIGRALMRAALEAARERGARAVVLLGDPSLLPFYERFGFRPAG 125
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
98-176 1.09e-07

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 49.03  E-value: 1.09e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386766727  98 NEIIGAASLVIERkfihncAVRGRLEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKDKLIKFYESLGYVAI 176
Cdd:COG2153   43 GELVATARLLPPG------DGEAKIGRVAVLPEYRGQGLGRALMEAAIEEARERGARRIVLSAQAHAVGFYEKLGFVPV 115
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
42-174 6.58e-07

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 47.68  E-value: 6.58e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  42 MKVRPLKDTDYDRgFLQLLSQLTHVGN-------VNRTQFLTRFSQMKASGdYFVTVIEDtrKNEIIGAASLVIERKFih 114
Cdd:COG1247    2 MTIRPATPEDAPA-IAAIYNEAIAEGTatfetepPSEEEREAWFAAILAPG-RPVLVAEE--DGEVVGFASLGPFRPR-- 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386766727 115 nCAVRGRLED-VVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKD---KLIKFYESLGYV 174
Cdd:COG1247   76 -PAYRGTAEEsIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLAdneASIALYEKLGFE 138
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 119-176 4.01e-06

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 43.88  E-value: 4.01e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386766727 119 RGRLEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKD---KLIKFYESLGYVAI 176
Cdd:COG0456   13 EAEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREdneAAIALYEKLGFEEV 73
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 77-176 8.76e-06

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 43.80  E-value: 8.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727   77 RFSQMKASGDYFVTVIEDtrKNEIIGAASLvierkfihncAVRGRLEDVVVNDTYRGKQLGKLIVVTV--SLLAEELGCY 154
Cdd:pfam13673  21 ALRERIDQGEYFFFVAFE--GGQIVGVIAL----------RDRGHISLLFVDPDYQGQGIGKALLEAVedYAEKDGIKLS 88

                          90       100
                  ....*....|....*....|..
gi 386766727  155 KMSLDCKDKLIKFYESLGYVAI 176
Cdd:pfam13673  89 ELTVNASPYAVPFYEKLGFRAT 110
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 91-159 1.29e-04

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 38.80  E-value: 1.29e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386766727  91 VIEDtrKNEIIGAASLVIERKFIHncavRGRLEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLD 159
Cdd:cd04301    3 VAED--DGEIVGFASLSPDGSGGD----TAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
99-176 1.45e-04

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 39.51  E-value: 1.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  99 EIIGAASLVIERKFIhncavrGRLEDVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKMSLDCKD---KLIKFYESLGYVA 175
Cdd:COG3393    1 ELVAMAGVRAESPGV------AEISGVYTHPEYRGRGLASALVAALAREALARGARTPFLYVDAdnpAARRLYERLGFRP 74


                 .
gi 386766727 176 I 176
Cdd:COG3393   75 V 75
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 42-174 1.31e-03

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 38.44  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  42 MKVRPLKDTDYDRgFLQLLSQ---LTHVGNVNRT-----QFLTRFSQMKASGDYFVTVIEDTRKNEIIGAASLVIERkfi 113
Cdd:COG1670    8 LRLRPLRPEDAEA-LAELLNDpevARYLPGPPYSleearAWLERLLADWADGGALPFAIEDKEDGELIGVVGLYDID--- 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386766727 114 hncAVRGRLE-DVVVNDTYRGKQLGKLIVVTV-SLLAEELGCYKMSLDCKD---KLIKFYESLGYV 174
Cdd:COG1670   84 ---RANRSAEiGYWLAPAYWGKGYATEALRALlDYAFEELGLHRVEAEVDPdntASIRVLEKLGFR 146
PRK07757 PRK07757
N-acetyltransferase;
86-177 6.14e-03

N-acetyltransferase;


Pssm-ID: 236088 [Multi-domain]  Cd Length: 152  Bit Score: 35.94  E-value: 6.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386766727  86 DYFVTVIEDtrknEIIGAASLVIerkFIHNCA-VRGrledVVVNDTYRGKQLGKLIVVTVSLLAEELGCYKM-SLDCKDk 163
Cdd:PRK07757  42 DFYVAEEEG----EIVGCCALHI---LWEDLAeIRS----LAVSEDYRGQGIGRMLVEACLEEARELGVKRVfALTYQP- 109

                         90
                 ....*....|....
gi 386766727 164 liKFYESLGYVAIP 177
Cdd:PRK07757 110 --EFFEKLGFREVD 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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