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Conserved domains on  [gi|386768550|ref|NP_001246488|]
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uncharacterized protein Dmel_CG3253, isoform B [Drosophila melanogaster]

Protein Classification

glycosyltransferase family 49 protein( domain architecture ID 10621298)

glycosyltransferase family 49 protein such as beta-1,4-glucuronyltransferase 1, which transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_49 pfam13896
Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the ...
 52-371 6.33e-136

Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the glycosylation of the alpha-dystroglycan subunit. Dystroglycan is an integral member of the skeletal muscular dystrophin glycoprotein complex, which links dystrophin to proteins in the extracellular matrix.


:

Pssm-ID: 464027  Cd Length: 327  Bit Score: 391.23  E-value: 6.33e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550   52 VCLATQTSVERLNSLPQVAANWQGKMSVALFAAGpEEFVVLQYFVTYMRLCFAN--IRENATFHLLTPRDFDKLPRVAAL 129
Cdd:pfam13896   2 VTLATHGTVDFLDNLEPLVERWRGPISVAVFAPG-TDFSLALDYIAYLRRCFPSelVRENVTFHLVFPSEHMPPKQVTCP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  130 PLNMRGKFDCqypDRTLKALLKFRSLKTLQWRQRNTYPQNHMRNLARKGCQTKYVFLTDIDIVPSTNSVPQLNHFFR--- 206
Cdd:pfam13896  81 SALLSSSNDC---SELLSPLRKLVPPGANYAAQNLLYPINLLRNVARKGAQTHFVLVIDIDLYPSPGLAEKFLEFLArnk 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  207 -TANCTKSCAYVIPTFEIDVRATFPRSKNALVRLIRKGLARPFHEKVFIYNQYATNFSKWL--SPNTNETEVSVSHVVTN 283
Cdd:pfam13896 158 kLLNRTSPCVFVVPAFEVDANATVPRTKAELLRLLKNGEARPFHHKVCPKCHKPTNYDRWLnlSKNSDGLNLFVAYKVTY 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  284 FEFLYEPFYIAVDNAPAHDERFLGYGFTRNSQVYEMHIAGYQFYVLSPVFTGHWGLQRKQARPAWREQQNNANRRKF-DV 362
Cdd:pfam13896 238 WQDPWEPFYIGTRNDPLYDERFTWYGFDRISQVYELCVAGYEFHVLDNAFLVHKGIKETGYFHAAREAQNKKNRKLFrSR 317


                  ....*....
gi 386768550  363 FKSEIFVRY 371
Cdd:pfam13896 318 FKQELKAKY 326
 
Name Accession Description Interval E-value
Glyco_transf_49 pfam13896
Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the ...
 52-371 6.33e-136

Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the glycosylation of the alpha-dystroglycan subunit. Dystroglycan is an integral member of the skeletal muscular dystrophin glycoprotein complex, which links dystrophin to proteins in the extracellular matrix.


Pssm-ID: 464027  Cd Length: 327  Bit Score: 391.23  E-value: 6.33e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550   52 VCLATQTSVERLNSLPQVAANWQGKMSVALFAAGpEEFVVLQYFVTYMRLCFAN--IRENATFHLLTPRDFDKLPRVAAL 129
Cdd:pfam13896   2 VTLATHGTVDFLDNLEPLVERWRGPISVAVFAPG-TDFSLALDYIAYLRRCFPSelVRENVTFHLVFPSEHMPPKQVTCP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  130 PLNMRGKFDCqypDRTLKALLKFRSLKTLQWRQRNTYPQNHMRNLARKGCQTKYVFLTDIDIVPSTNSVPQLNHFFR--- 206
Cdd:pfam13896  81 SALLSSSNDC---SELLSPLRKLVPPGANYAAQNLLYPINLLRNVARKGAQTHFVLVIDIDLYPSPGLAEKFLEFLArnk 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  207 -TANCTKSCAYVIPTFEIDVRATFPRSKNALVRLIRKGLARPFHEKVFIYNQYATNFSKWL--SPNTNETEVSVSHVVTN 283
Cdd:pfam13896 158 kLLNRTSPCVFVVPAFEVDANATVPRTKAELLRLLKNGEARPFHHKVCPKCHKPTNYDRWLnlSKNSDGLNLFVAYKVTY 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  284 FEFLYEPFYIAVDNAPAHDERFLGYGFTRNSQVYEMHIAGYQFYVLSPVFTGHWGLQRKQARPAWREQQNNANRRKF-DV 362
Cdd:pfam13896 238 WQDPWEPFYIGTRNDPLYDERFTWYGFDRISQVYELCVAGYEFHVLDNAFLVHKGIKETGYFHAAREAQNKKNRKLFrSR 317


                  ....*....
gi 386768550  363 FKSEIFVRY 371
Cdd:pfam13896 318 FKQELKAKY 326
 
Name Accession Description Interval E-value
Glyco_transf_49 pfam13896
Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the ...
 52-371 6.33e-136

Glycosyl-transferase for dystroglycan; This glycosyl-transferase brings about the glycosylation of the alpha-dystroglycan subunit. Dystroglycan is an integral member of the skeletal muscular dystrophin glycoprotein complex, which links dystrophin to proteins in the extracellular matrix.


Pssm-ID: 464027  Cd Length: 327  Bit Score: 391.23  E-value: 6.33e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550   52 VCLATQTSVERLNSLPQVAANWQGKMSVALFAAGpEEFVVLQYFVTYMRLCFAN--IRENATFHLLTPRDFDKLPRVAAL 129
Cdd:pfam13896   2 VTLATHGTVDFLDNLEPLVERWRGPISVAVFAPG-TDFSLALDYIAYLRRCFPSelVRENVTFHLVFPSEHMPPKQVTCP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  130 PLNMRGKFDCqypDRTLKALLKFRSLKTLQWRQRNTYPQNHMRNLARKGCQTKYVFLTDIDIVPSTNSVPQLNHFFR--- 206
Cdd:pfam13896  81 SALLSSSNDC---SELLSPLRKLVPPGANYAAQNLLYPINLLRNVARKGAQTHFVLVIDIDLYPSPGLAEKFLEFLArnk 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  207 -TANCTKSCAYVIPTFEIDVRATFPRSKNALVRLIRKGLARPFHEKVFIYNQYATNFSKWL--SPNTNETEVSVSHVVTN 283
Cdd:pfam13896 158 kLLNRTSPCVFVVPAFEVDANATVPRTKAELLRLLKNGEARPFHHKVCPKCHKPTNYDRWLnlSKNSDGLNLFVAYKVTY 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386768550  284 FEFLYEPFYIAVDNAPAHDERFLGYGFTRNSQVYEMHIAGYQFYVLSPVFTGHWGLQRKQARPAWREQQNNANRRKF-DV 362
Cdd:pfam13896 238 WQDPWEPFYIGTRNDPLYDERFTWYGFDRISQVYELCVAGYEFHVLDNAFLVHKGIKETGYFHAAREAQNKKNRKLFrSR 317


                  ....*....
gi 386768550  363 FKSEIFVRY 371
Cdd:pfam13896 318 FKQELKAKY 326
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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