|
Name |
Accession |
Description |
Interval |
E-value |
| Frem_N |
pfam19309 |
Frem protein N-terminal domain; This entry represents a presumed domain found at the ... |
63-275 |
1.78e-121 |
|
Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.
:
Pssm-ID: 466034 Cd Length: 202 Bit Score: 381.68 E-value: 1.78e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 63 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVAVLDNDALAQRPGRLSPKRFACDYGPGEVRYSHLGARSPSRDRV 142
Cdd:pfam19309 1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 143 RLQLRYDAPGGAIVLPLALEVEVVFTQLEVVTRNLPLVVEELLGTSNALDARSLEFAYQPETEECRVGILSGLSALPRYG 222
Cdd:pfam19309 81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 350534782 223 ELLHYPQVPGgtgergssetpLMDCKAFQELGVRYRHTALSHSPNRDWLPMVV 275
Cdd:pfam19309 161 RLVNATGAPL-----------MVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1503-1610 |
5.40e-34 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 127.72 E-value: 5.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1503 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1579
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
|
90 100 110
....*....|....*....|....*....|.
gi 350534782 1580 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1610
Cdd:pfam16184 81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1393-1501 |
1.61e-32 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 123.48 E-value: 1.61e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1393 IDRYFYVSIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDQRGLSITSFTQ 1471
Cdd:pfam16184 3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
|
90 100 110
....*....|....*....|....*....|
gi 350534782 1472 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1501
Cdd:pfam16184 83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1273-1388 |
2.45e-32 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 122.71 E-value: 2.45e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1273 HSVEKMALIMVIPVDDETPRMAINNGLEIEIGETKVINNKVLAATDLDSDDKSLVYIIRYGPGHGLLQRRKPLGVfeNIT 1352
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL--PVT 78
|
90 100 110
....*....|....*....|....*....|....*.
gi 350534782 1353 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1388
Cdd:pfam16184 79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
413-530 |
7.83e-31 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 118.47 E-value: 7.83e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 413 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpvgsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSS 491
Cdd:pfam16184 2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPGL 75
|
90 100 110
....*....|....*....|....*....|....*....
gi 350534782 492 dpAPKTFTVAELAAGQVVYQHDDRDgSLCDNLVLRMSDG 530
Cdd:pfam16184 76 --PVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1161-1271 |
3.15e-27 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 108.46 E-value: 3.15e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1161 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVDTPILNAADADIPRDDLTFTITRFPTHGHIMNQLiNGTVLVESF 1239
Cdd:pfam16184 2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
|
90 100 110
....*....|....*....|....*....|..
gi 350534782 1240 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1271
Cdd:pfam16184 81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
534-663 |
6.78e-25 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 101.53 E-value: 6.78e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 534 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGDTVPIPPSTLSATDMDSDDSQLLF-VLEPPfsSSGRLLLRqthapqee 612
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYtVVQGP--SHGHLALK-------- 70
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 350534782 613 qglwhkqgSFYERMVTEWRQQDITEGKLFYRHSGphsPGPVMDQFLFRVQD 663
Cdd:pfam16184 71 --------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1040-1157 |
1.24e-22 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 94.98 E-value: 1.24e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1040 VTVWVTILPVDSQAPEISVGEQFVVLEGDKSLISLTHLSAEDVDSLMDDLLCTIVIQPTSGYVENispapgseKSRAGIA 1119
Cdd:pfam16184 5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 350534782 1120 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1157
Cdd:pfam16184 77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1628-1740 |
1.09e-20 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 89.58 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1628 PQVMKIRVLPVDNRVPQIVVNKGastLRTLPTGHlgFMITSKILKVQDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1707
Cdd:pfam16184 4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
|
90 100 110
....*....|....*....|....*....|...
gi 350534782 1708 QFTQADIDDMKICYVlRERANATSDVFHFIVED 1740
Cdd:pfam16184 79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
|
|
| caca super family |
cl36745 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
2095-2330 |
9.60e-20 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
The actual alignment was detected with superfamily member TIGR00845:
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 97.56 E-value: 9.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2095 AALGEPSKATVSINDSASDLP-KMQFKERVYTCSENDGHV-VAMIYRSGDLQHRSSVRCYTRQGSAQVMMDFEERPNTdi 2172
Cdd:TIGR00845 379 AARKAVSMHEVATDDEENDPVsKIFFEPGHYTCLENCGTVaLTVVRRGGDLTNTVYVDYRTEDGTANAGSDYEFTEGT-- 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2173 siVTFLPGESEKPCVLELMDDDLYEDVEELRLVLGTPQGSSAFGAAVGEQNETL----------IKIQDDADKAVIKFGE 2242
Cdd:TIGR00845 457 --LVFKPGETQKEFRIGIIDDDIFEEDEHFYVRLSNLRVGSEDGILEANHVSAVaqlaspntatVTILDDDHAGIFTFEE 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2243 TKFSVTEPSRpgesvVVKIPVIRQGDTSKVSIVRVHTKDGSAT-SGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMR 2321
Cdd:TIGR00845 535 DVFHVSESIG-----IMEVKVLRTSGARGTVIVPYRTVEGTARgGGKDFEDTCGELEFENDETEKTIRVKIVDDEEYEKN 609
|
....*....
gi 350534782 2322 EAFTVHLKP 2330
Cdd:TIGR00845 610 DTFFIELGE 618
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
802-907 |
2.74e-19 |
|
Cadherin-like;
:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 85.73 E-value: 2.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 802 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHVLRETELHVSDVDTDVAHISFTLTQAPKHGHLQISGRPLHVGGQFRLE 880
Cdd:pfam16184 4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
|
90 100
....*....|....*....|....*..
gi 350534782 881 DIKQGRISYLNSGDESLTDSCSLEVSD 907
Cdd:pfam16184 84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
|
|
| caca super family |
cl36745 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
1758-1995 |
4.76e-17 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
The actual alignment was detected with superfamily member TIGR00845:
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 88.70 E-value: 4.76e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1758 ISFEKEYYLINEDSKFLDIVLKRRGY-LGETSFISISTRDGTAEKDKDFKGkAQKQVQFNPGQTRASWRVRILSDGEHEH 1836
Cdd:TIGR00845 402 IFFEPGHYTCLENCGTVALTVVRRGGdLTNTVYVDYRTEDGTANAGSDYEF-TEGTLVFKPGETQKEFRIGIIDDDIFEE 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1837 SETFQVVLSEP---------------VLAVLEFPEVTTVEIIDpGDESTVF-IPQSEYSVEEDVSELFIPIRRSGDISQE 1900
Cdd:TIGR00845 481 DEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD-DDHAGIFtFEEDVFHVSESIGIMEVKVLRTSGARGT 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1901 LMVICYTQQGTATStvrtsvlSYSDYisrpEDHSSVIRFDKDEREKMCRVVVIDDSLYEEEETFQVLLSMPMGGRIGNKF 1980
Cdd:TIGR00845 560 VIVPYRTVEGTARG-------GGKDF----EDTCGELEFENDETEKTIRVKIVDDEEYEKNDTFFIELGEPRWAKRGIKA 628
|
250
....*....|....*
gi 350534782 1981 PGANVTILTDKDDEP 1995
Cdd:TIGR00845 629 ALLLNETITDDDQKL 643
|
|
| Calx-beta super family |
cl02522 |
Calx-beta domain; |
1997-2089 |
5.05e-15 |
|
Calx-beta domain;
The actual alignment was detected with superfamily member pfam03160:
Pssm-ID: 413355 [Multi-domain] Cd Length: 91 Bit Score: 72.67 E-value: 5.05e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1997 FYFGDTQHSVDESAGYVEVQVWRTGTDLTKPSSVTVRsrkTEPPSADAGTDYVGISRNLDFAPGVSMQTVRVVILDDLgr 2076
Cdd:pfam03160 4 IGFEPPTYQVSENDGVAEVCVVRMSGTLRRTVVVPYR---TEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDDD-- 78
|
90
....*....|...
gi 350534782 2077 pVLEGIEKFELVL 2089
Cdd:pfam03160 79 -VYEGDENFFVLL 90
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
670-795 |
2.32e-14 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 71.48 E-value: 2.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 670 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELHYTVTQPPtdtdeNHspaplGTLV 749
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 350534782 750 FTDNPSVVVTHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 795
Cdd:pfam16184 69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
910-1024 |
1.58e-13 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 69.17 E-value: 1.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 910 HVVPITLRVNVRPADREGAMSVLPAGtlesyLDVLENGATEVTANIIKGTYRDTDDLMLTFLLEGPPLYGEILVHGAP-- 987
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
|
90 100 110
....*....|....*....|....*....|....*...
gi 350534782 988 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1024
Cdd:pfam16184 76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
|
|
| Cadherin_3 super family |
cl28802 |
Cadherin-like; |
327-387 |
8.41e-09 |
|
Cadherin-like;
The actual alignment was detected with superfamily member pfam16184:
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 55.69 E-value: 8.41e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 350534782 327 TALTPDMLAAEDAESNPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 387
Cdd:pfam16184 35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Frem_N |
pfam19309 |
Frem protein N-terminal domain; This entry represents a presumed domain found at the ... |
63-275 |
1.78e-121 |
|
Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.
Pssm-ID: 466034 Cd Length: 202 Bit Score: 381.68 E-value: 1.78e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 63 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVAVLDNDALAQRPGRLSPKRFACDYGPGEVRYSHLGARSPSRDRV 142
Cdd:pfam19309 1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 143 RLQLRYDAPGGAIVLPLALEVEVVFTQLEVVTRNLPLVVEELLGTSNALDARSLEFAYQPETEECRVGILSGLSALPRYG 222
Cdd:pfam19309 81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 350534782 223 ELLHYPQVPGgtgergssetpLMDCKAFQELGVRYRHTALSHSPNRDWLPMVV 275
Cdd:pfam19309 161 RLVNATGAPL-----------MVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1503-1610 |
5.40e-34 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 127.72 E-value: 5.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1503 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1579
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
|
90 100 110
....*....|....*....|....*....|.
gi 350534782 1580 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1610
Cdd:pfam16184 81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1393-1501 |
1.61e-32 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 123.48 E-value: 1.61e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1393 IDRYFYVSIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDQRGLSITSFTQ 1471
Cdd:pfam16184 3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
|
90 100 110
....*....|....*....|....*....|
gi 350534782 1472 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1501
Cdd:pfam16184 83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1273-1388 |
2.45e-32 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 122.71 E-value: 2.45e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1273 HSVEKMALIMVIPVDDETPRMAINNGLEIEIGETKVINNKVLAATDLDSDDKSLVYIIRYGPGHGLLQRRKPLGVfeNIT 1352
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL--PVT 78
|
90 100 110
....*....|....*....|....*....|....*.
gi 350534782 1353 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1388
Cdd:pfam16184 79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
413-530 |
7.83e-31 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 118.47 E-value: 7.83e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 413 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpvgsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSS 491
Cdd:pfam16184 2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPGL 75
|
90 100 110
....*....|....*....|....*....|....*....
gi 350534782 492 dpAPKTFTVAELAAGQVVYQHDDRDgSLCDNLVLRMSDG 530
Cdd:pfam16184 76 --PVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1161-1271 |
3.15e-27 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 108.46 E-value: 3.15e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1161 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVDTPILNAADADIPRDDLTFTITRFPTHGHIMNQLiNGTVLVESF 1239
Cdd:pfam16184 2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
|
90 100 110
....*....|....*....|....*....|..
gi 350534782 1240 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1271
Cdd:pfam16184 81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
534-663 |
6.78e-25 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 101.53 E-value: 6.78e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 534 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGDTVPIPPSTLSATDMDSDDSQLLF-VLEPPfsSSGRLLLRqthapqee 612
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYtVVQGP--SHGHLALK-------- 70
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 350534782 613 qglwhkqgSFYERMVTEWRQQDITEGKLFYRHSGphsPGPVMDQFLFRVQD 663
Cdd:pfam16184 71 --------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1040-1157 |
1.24e-22 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 94.98 E-value: 1.24e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1040 VTVWVTILPVDSQAPEISVGEQFVVLEGDKSLISLTHLSAEDVDSLMDDLLCTIVIQPTSGYVENispapgseKSRAGIA 1119
Cdd:pfam16184 5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 350534782 1120 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1157
Cdd:pfam16184 77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1628-1740 |
1.09e-20 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 89.58 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1628 PQVMKIRVLPVDNRVPQIVVNKGastLRTLPTGHlgFMITSKILKVQDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1707
Cdd:pfam16184 4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
|
90 100 110
....*....|....*....|....*....|...
gi 350534782 1708 QFTQADIDDMKICYVlRERANATSDVFHFIVED 1740
Cdd:pfam16184 79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
2095-2330 |
9.60e-20 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 97.56 E-value: 9.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2095 AALGEPSKATVSINDSASDLP-KMQFKERVYTCSENDGHV-VAMIYRSGDLQHRSSVRCYTRQGSAQVMMDFEERPNTdi 2172
Cdd:TIGR00845 379 AARKAVSMHEVATDDEENDPVsKIFFEPGHYTCLENCGTVaLTVVRRGGDLTNTVYVDYRTEDGTANAGSDYEFTEGT-- 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2173 siVTFLPGESEKPCVLELMDDDLYEDVEELRLVLGTPQGSSAFGAAVGEQNETL----------IKIQDDADKAVIKFGE 2242
Cdd:TIGR00845 457 --LVFKPGETQKEFRIGIIDDDIFEEDEHFYVRLSNLRVGSEDGILEANHVSAVaqlaspntatVTILDDDHAGIFTFEE 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2243 TKFSVTEPSRpgesvVVKIPVIRQGDTSKVSIVRVHTKDGSAT-SGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMR 2321
Cdd:TIGR00845 535 DVFHVSESIG-----IMEVKVLRTSGARGTVIVPYRTVEGTARgGGKDFEDTCGELEFENDETEKTIRVKIVDDEEYEKN 609
|
....*....
gi 350534782 2322 EAFTVHLKP 2330
Cdd:TIGR00845 610 DTFFIELGE 618
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
802-907 |
2.74e-19 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 85.73 E-value: 2.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 802 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHVLRETELHVSDVDTDVAHISFTLTQAPKHGHLQISGRPLHVGGQFRLE 880
Cdd:pfam16184 4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
|
90 100
....*....|....*....|....*..
gi 350534782 881 DIKQGRISYLNSGDESLTDSCSLEVSD 907
Cdd:pfam16184 84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
1758-1995 |
4.76e-17 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 88.70 E-value: 4.76e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1758 ISFEKEYYLINEDSKFLDIVLKRRGY-LGETSFISISTRDGTAEKDKDFKGkAQKQVQFNPGQTRASWRVRILSDGEHEH 1836
Cdd:TIGR00845 402 IFFEPGHYTCLENCGTVALTVVRRGGdLTNTVYVDYRTEDGTANAGSDYEF-TEGTLVFKPGETQKEFRIGIIDDDIFEE 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1837 SETFQVVLSEP---------------VLAVLEFPEVTTVEIIDpGDESTVF-IPQSEYSVEEDVSELFIPIRRSGDISQE 1900
Cdd:TIGR00845 481 DEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD-DDHAGIFtFEEDVFHVSESIGIMEVKVLRTSGARGT 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1901 LMVICYTQQGTATStvrtsvlSYSDYisrpEDHSSVIRFDKDEREKMCRVVVIDDSLYEEEETFQVLLSMPMGGRIGNKF 1980
Cdd:TIGR00845 560 VIVPYRTVEGTARG-------GGKDF----EDTCGELEFENDETEKTIRVKIVDDEEYEKNDTFFIELGEPRWAKRGIKA 628
|
250
....*....|....*
gi 350534782 1981 PGANVTILTDKDDEP 1995
Cdd:TIGR00845 629 ALLLNETITDDDQKL 643
|
|
| Calx-beta |
pfam03160 |
Calx-beta domain; |
1997-2089 |
5.05e-15 |
|
Calx-beta domain;
Pssm-ID: 397326 [Multi-domain] Cd Length: 91 Bit Score: 72.67 E-value: 5.05e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1997 FYFGDTQHSVDESAGYVEVQVWRTGTDLTKPSSVTVRsrkTEPPSADAGTDYVGISRNLDFAPGVSMQTVRVVILDDLgr 2076
Cdd:pfam03160 4 IGFEPPTYQVSENDGVAEVCVVRMSGTLRRTVVVPYR---TEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDDD-- 78
|
90
....*....|...
gi 350534782 2077 pVLEGIEKFELVL 2089
Cdd:pfam03160 79 -VYEGDENFFVLL 90
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
670-795 |
2.32e-14 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 71.48 E-value: 2.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 670 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELHYTVTQPPtdtdeNHspaplGTLV 749
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 350534782 750 FTDNPSVVVTHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 795
Cdd:pfam16184 69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
|
|
| Calx-beta |
pfam03160 |
Calx-beta domain; |
2237-2328 |
2.38e-14 |
|
Calx-beta domain;
Pssm-ID: 397326 [Multi-domain] Cd Length: 91 Bit Score: 70.74 E-value: 2.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2237 VIKFGETKFSVTEpsrpgESVVVKIPVIRQ-GDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFD 2315
Cdd:pfam03160 3 VIGFEPPTYQVSE-----NDGVAEVCVVRMsGTLRRTVVVPYRTEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDD 77
|
90
....*....|...
gi 350534782 2316 GVREMREAFTVHL 2328
Cdd:pfam03160 78 DVYEGDENFFVLL 90
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
1977-2210 |
2.43e-14 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 79.84 E-value: 2.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1977 GNKFPGANVTILTDKDDEPA--FYFGDTQHSVDESAGYVEVQVWRTGTDLTKPSSVTVRsrkTEPPSADAGTDYVGISRN 2054
Cdd:TIGR00845 380 ARKAVSMHEVATDDEENDPVskIFFEPGHYTCLENCGTVALTVVRRGGDLTNTVYVDYR---TEDGTANAGSDYEFTEGT 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2055 LDFAPGVSMQTVRVVILDDlgrPVLEGIEKFELVLRMP---------------MNAALGEPSKATVSINDsaSDLPKM-Q 2118
Cdd:TIGR00845 457 LVFKPGETQKEFRIGIIDD---DIFEEDEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD--DDHAGIfT 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2119 FKERVYTCSENDGHV-VAMIYRSGdlqHRSSVRC--YTRQGSAQV-MMDFEErpnTDISIVtFLPGESEKPCVLELMDDD 2194
Cdd:TIGR00845 532 FEEDVFHVSESIGIMeVKVLRTSG---ARGTVIVpyRTVEGTARGgGKDFED---TCGELE-FENDETEKTIRVKIVDDE 604
|
250
....*....|....*.
gi 350534782 2195 LYEDVEELRLVLGTPQ 2210
Cdd:TIGR00845 605 EYEKNDTFFIELGEPR 620
|
|
| Calx_beta |
smart00237 |
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ... |
2237-2328 |
1.16e-13 |
|
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)
Pssm-ID: 197594 [Multi-domain] Cd Length: 90 Bit Score: 68.82 E-value: 1.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2237 VIKFGETKFSVTEpsrpgESVVVKIPVIRQGDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFDG 2316
Cdd:smart00237 3 SVGFEQPVYTVSE-----SDGEVEVCVVRTGGARGPVVVPYSTEDGTATAGSDYEPVPGELTFPPGETEKEIRIKIIDDD 77
|
90
....*....|..
gi 350534782 2317 VREMREAFTVHL 2328
Cdd:smart00237 78 IYEKDETFYVRL 89
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
910-1024 |
1.58e-13 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 69.17 E-value: 1.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 910 HVVPITLRVNVRPADREGAMSVLPAGtlesyLDVLENGATEVTANIIKGTYRDTDDLMLTFLLEGPPLYGEILVHGAP-- 987
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
|
90 100 110
....*....|....*....|....*....|....*...
gi 350534782 988 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1024
Cdd:pfam16184 76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
|
|
| Calx_beta |
smart00237 |
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ... |
1997-2089 |
1.43e-12 |
|
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)
Pssm-ID: 197594 [Multi-domain] Cd Length: 90 Bit Score: 65.74 E-value: 1.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1997 FYFGDTQHSVDESAGYVEVQVWRTGtDLTKPSSVTVRsrkTEPPSADAGTDYVGISRNLDFAPGVSMQTVRVVILDDlgr 2076
Cdd:smart00237 4 VGFEQPVYTVSESDGEVEVCVVRTG-GARGPVVVPYS---TEDGTATAGSDYEPVPGELTFPPGETEKEIRIKIIDD--- 76
|
90
....*....|...
gi 350534782 2077 PVLEGIEKFELVL 2089
Cdd:smart00237 77 DIYEKDETFYVRL 89
|
|
| Calx-beta |
pfam03160 |
Calx-beta domain; |
1758-1845 |
5.89e-11 |
|
Calx-beta domain;
Pssm-ID: 397326 [Multi-domain] Cd Length: 91 Bit Score: 61.11 E-value: 5.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1758 ISFEKEYYLINEDSKFLDI-VLKRRGYLGETSFISISTRDGTAEKDKDFKGKAQkQVQFNPGQTRASWRVRILSDGEHEH 1836
Cdd:pfam03160 4 IGFEPPTYQVSENDGVAEVcVVRMSGTLRRTVVVPYRTEDGTATAGDDYEPVEG-ELVFGPGETEKCINVTIIDDDVYEG 82
|
....*....
gi 350534782 1837 SETFQVVLS 1845
Cdd:pfam03160 83 DENFFVLLS 91
|
|
| Calx_beta |
smart00237 |
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ... |
1869-1969 |
6.18e-11 |
|
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)
Pssm-ID: 197594 [Multi-domain] Cd Length: 90 Bit Score: 61.12 E-value: 6.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1869 STVFIPQSEYSVEEDVSELFIPIRRSGDISQELMVICYTQQGTATSTvrtsvlsySDYISRPedhsSVIRFDKDEREKMC 1948
Cdd:smart00237 2 GSVGFEQPVYTVSESDGEVEVCVVRTGGARGPVVVPYSTEDGTATAG--------SDYEPVP----GELTFPPGETEKEI 69
|
90 100
....*....|....*....|.
gi 350534782 1949 RVVVIDDSLYEEEETFQVLLS 1969
Cdd:smart00237 70 RIKIIDDDIYEKDETFYVRLS 90
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
327-387 |
8.41e-09 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 55.69 E-value: 8.41e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 350534782 327 TALTPDMLAAEDAESNPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 387
Cdd:pfam16184 35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Frem_N |
pfam19309 |
Frem protein N-terminal domain; This entry represents a presumed domain found at the ... |
63-275 |
1.78e-121 |
|
Frem protein N-terminal domain; This entry represents a presumed domain found at the N-terminus of Frem related proteins.
Pssm-ID: 466034 Cd Length: 202 Bit Score: 381.68 E-value: 1.78e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 63 IVVANRGLRVPFGREVWLDPLRDLVLQVQPGDRCTVAVLDNDALAQRPGRLSPKRFACDYGPGEVRYSHLGARSPSRDRV 142
Cdd:pfam19309 1 ILIANRGLRVPFGRSVWLDPLRDLVIQVQPGDRCEVTVLDNDPLPQRPGALSPRRFPCDFGPREVQYTHFGSRSPSRDRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 143 RLQLRYDAPGGAIVLPLALEVEVVFTQLEVVTRNLPLVVEELLGTSNALDARSLEFAYQPETEECRVGILSGLSALPRYG 222
Cdd:pfam19309 81 RLQLRYDAPTDTLVLPFTLEVEVVFSQLEIVTRNLPLTVEKLLGTSNPIDRRVLEFAYDPGTERCKVTVLPGAGGLPRYG 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 350534782 223 ELLHYPQVPGgtgergssetpLMDCKAFQELGVRYRHTALSHSPNRDWLPMVV 275
Cdd:pfam19309 161 RLVNATGAPL-----------MVDCEAFLRAGVRYQHTATTSSPNRDYVPMVV 202
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1503-1610 |
5.40e-34 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 127.72 E-value: 5.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1503 NPVFRTFRISISDVDNKKPVVTIHN-LVVSESESKLITPFELTVEDRDTPDRLLKFIVTQVPVHGHLLFNNTRSVMV--F 1579
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVtnF 80
|
90 100 110
....*....|....*....|....*....|.
gi 350534782 1580 TKQDLNENLISYKHDGTESTEDSFSFTVTDG 1610
Cdd:pfam16184 81 TQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1393-1501 |
1.61e-32 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 123.48 E-value: 1.61e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1393 IDRYFYVSIGSVDIVFPDVV-SKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDQRGLSITSFTQ 1471
Cdd:pfam16184 3 VPFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQ 82
|
90 100 110
....*....|....*....|....*....|
gi 350534782 1472 LQLAGNKIYYIHTAeDEVKMDSFEFQVTDG 1501
Cdd:pfam16184 83 ADIDSGLVVYVHDG-SESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1273-1388 |
2.45e-32 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 122.71 E-value: 2.45e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1273 HSVEKMALIMVIPVDDETPRMAINNGLEIEIGETKVINNKVLAATDLDSDDKSLVYIIRYGPGHGLLQRRKPLGVfeNIT 1352
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGL--PVT 78
|
90 100 110
....*....|....*....|....*....|....*.
gi 350534782 1353 lgmNFTQDEVDRNLIQYVHFGQEGIRDLIKFDVTDG 1388
Cdd:pfam16184 79 ---NFTQADIDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
413-530 |
7.83e-31 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 118.47 E-value: 7.83e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 413 SDPFAFMVVVKPMNTLAPVVTRNTGLILYEGQYRPLTgpvgsgPQNLVISDEDDL-EAVRLEVVAGLRHGHLVILGSPSS 491
Cdd:pfam16184 2 SVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPIT------PDLLQAEDPDTPpEDLTYTVVQGPSHGHLALKGAPGL 75
|
90 100 110
....*....|....*....|....*....|....*....
gi 350534782 492 dpAPKTFTVAELAAGQVVYQHDDRDgSLCDNLVLRMSDG 530
Cdd:pfam16184 76 --PVTNFTQADIDSGLVVYVHDGSE-STSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1161-1271 |
3.15e-27 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 108.46 E-value: 3.15e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1161 SERQIFPIVIIPTNDEQPEMFMRE-FMVMEGMSLVVDTPILNAADADIPRDDLTFTITRFPTHGHIMNQLiNGTVLVESF 1239
Cdd:pfam16184 2 SVPFTFNITIIPVNDEAPVLTTNTgLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKG-APGLPVTNF 80
|
90 100 110
....*....|....*....|....*....|..
gi 350534782 1240 TLDQiIESSSIIYEHDDSETQEDSFVIKLTDG 1271
Cdd:pfam16184 81 TQAD-IDSGLVVYVHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
534-663 |
6.78e-25 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 101.53 E-value: 6.78e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 534 HQVQFLFPITLVPVDDQPPVLNANTGLTVAEGDTVPIPPSTLSATDMDSDDSQLLF-VLEPPfsSSGRLLLRqthapqee 612
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYtVVQGP--SHGHLALK-------- 70
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 350534782 613 qglwhkqgSFYERMVTEWRQQDITEGKLFYRHSGphsPGPVMDQFLFRVQD 663
Cdd:pfam16184 71 --------GAPGLPVTNFTQADIDSGLVVYVHDG---SESTSDGFTFQVTD 110
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1040-1157 |
1.24e-22 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 94.98 E-value: 1.24e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1040 VTVWVTILPVDSQAPEISVGEQFVVLEGDKSLISLTHLSAEDVDSLMDDLLCTIVIQPTSGYVENispapgseKSRAGIA 1119
Cdd:pfam16184 5 FTFNITIIPVNDEAPVLTTNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLAL--------KGAPGLP 76
|
90 100 110
....*....|....*....|....*....|....*...
gi 350534782 1120 ISAFTLKDLRQGHINYvqsVHRGVEPVEDRFIFRCSDG 1157
Cdd:pfam16184 77 VTNFTQADIDSGLVVY---VHDGSESTSDGFTFQVTDG 111
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
1628-1740 |
1.09e-20 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 89.58 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1628 PQVMKIRVLPVDNRVPQIVVNKGastLRTLPTGHlgFMITSKILKVQDRDSLHFSLRFIVTEAPQHGYLLNLGQGNHSVT 1707
Cdd:pfam16184 4 PFTFNITIIPVNDEAPVLTTNTG---LRLWEGSS--RPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVT 78
|
90 100 110
....*....|....*....|....*....|...
gi 350534782 1708 QFTQADIDDMKICYVlRERANATSDVFHFIVED 1740
Cdd:pfam16184 79 NFTQADIDSGLVVYV-HDGSESTSDGFTFQVTD 110
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
2095-2330 |
9.60e-20 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 97.56 E-value: 9.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2095 AALGEPSKATVSINDSASDLP-KMQFKERVYTCSENDGHV-VAMIYRSGDLQHRSSVRCYTRQGSAQVMMDFEERPNTdi 2172
Cdd:TIGR00845 379 AARKAVSMHEVATDDEENDPVsKIFFEPGHYTCLENCGTVaLTVVRRGGDLTNTVYVDYRTEDGTANAGSDYEFTEGT-- 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2173 siVTFLPGESEKPCVLELMDDDLYEDVEELRLVLGTPQGSSAFGAAVGEQNETL----------IKIQDDADKAVIKFGE 2242
Cdd:TIGR00845 457 --LVFKPGETQKEFRIGIIDDDIFEEDEHFYVRLSNLRVGSEDGILEANHVSAVaqlaspntatVTILDDDHAGIFTFEE 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2243 TKFSVTEPSRpgesvVVKIPVIRQGDTSKVSIVRVHTKDGSAT-SGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMR 2321
Cdd:TIGR00845 535 DVFHVSESIG-----IMEVKVLRTSGARGTVIVPYRTVEGTARgGGKDFEDTCGELEFENDETEKTIRVKIVDDEEYEKN 609
|
....*....
gi 350534782 2322 EAFTVHLKP 2330
Cdd:TIGR00845 610 DTFFIELGE 618
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
802-907 |
2.74e-19 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 85.73 E-value: 2.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 802 PGTFTLYLQPVDNQPPEIV-NTGFTVEEKGHHVLRETELHVSDVDTDVAHISFTLTQAPKHGHLQISGRPLHVGGQFRLE 880
Cdd:pfam16184 4 PFTFNITIIPVNDEAPVLTtNTGLRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPGLPVTNFTQA 83
|
90 100
....*....|....*....|....*..
gi 350534782 881 DIKQGRISYLNSGDESLTDSCSLEVSD 907
Cdd:pfam16184 84 DIDSGLVVYVHDGSESTSDGFTFQVTD 110
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
1758-1995 |
4.76e-17 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 88.70 E-value: 4.76e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1758 ISFEKEYYLINEDSKFLDIVLKRRGY-LGETSFISISTRDGTAEKDKDFKGkAQKQVQFNPGQTRASWRVRILSDGEHEH 1836
Cdd:TIGR00845 402 IFFEPGHYTCLENCGTVALTVVRRGGdLTNTVYVDYRTEDGTANAGSDYEF-TEGTLVFKPGETQKEFRIGIIDDDIFEE 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1837 SETFQVVLSEP---------------VLAVLEFPEVTTVEIIDpGDESTVF-IPQSEYSVEEDVSELFIPIRRSGDISQE 1900
Cdd:TIGR00845 481 DEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD-DDHAGIFtFEEDVFHVSESIGIMEVKVLRTSGARGT 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1901 LMVICYTQQGTATStvrtsvlSYSDYisrpEDHSSVIRFDKDEREKMCRVVVIDDSLYEEEETFQVLLSMPMGGRIGNKF 1980
Cdd:TIGR00845 560 VIVPYRTVEGTARG-------GGKDF----EDTCGELEFENDETEKTIRVKIVDDEEYEKNDTFFIELGEPRWAKRGIKA 628
|
250
....*....|....*
gi 350534782 1981 PGANVTILTDKDDEP 1995
Cdd:TIGR00845 629 ALLLNETITDDDQKL 643
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
1864-2117 |
3.80e-15 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 82.53 E-value: 3.80e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1864 DPGDE-STVFIPQSEYSVEEDVSELFIPI-RRSGDISQELMVICYTQQGTATSTvrtsvlsySDYISRpedhSSVIRFDK 1941
Cdd:TIGR00845 394 EENDPvSKIFFEPGHYTCLENCGTVALTVvRRGGDLTNTVYVDYRTEDGTANAG--------SDYEFT----EGTLVFKP 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1942 DEREKMCRVVVIDDSLYEEEETFQVLLSMPMGGRIGNKFPG--------------ANVTILtDKDDEPAFYFGDTQHSVD 2007
Cdd:TIGR00845 462 GETQKEFRIGIIDDDIFEEDEHFYVRLSNLRVGSEDGILEAnhvsavaqlaspntATVTIL-DDDHAGIFTFEEDVFHVS 540
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2008 ESAGYVEVQVWRT----GTdltkpssVTVRSRKTEPPSADAGTDYVGISRNLDFAPGVSMQTVRVVILDD---------- 2073
Cdd:TIGR00845 541 ESIGIMEVKVLRTsgarGT-------VIVPYRTVEGTARGGGKDFEDTCGELEFENDETEKTIRVKIVDDeeyekndtff 613
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 350534782 2074 --LGRPVLegIEKFELVLRMPmNAALGEPSKATVSINDSASDLPKM 2117
Cdd:TIGR00845 614 ieLGEPRW--AKRGIKAALLL-NETITDDDQKLTSKEEEERRIAEM 656
|
|
| Calx-beta |
pfam03160 |
Calx-beta domain; |
1997-2089 |
5.05e-15 |
|
Calx-beta domain;
Pssm-ID: 397326 [Multi-domain] Cd Length: 91 Bit Score: 72.67 E-value: 5.05e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1997 FYFGDTQHSVDESAGYVEVQVWRTGTDLTKPSSVTVRsrkTEPPSADAGTDYVGISRNLDFAPGVSMQTVRVVILDDLgr 2076
Cdd:pfam03160 4 IGFEPPTYQVSENDGVAEVCVVRMSGTLRRTVVVPYR---TEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDDD-- 78
|
90
....*....|...
gi 350534782 2077 pVLEGIEKFELVL 2089
Cdd:pfam03160 79 -VYEGDENFFVLL 90
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
670-795 |
2.32e-14 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 71.48 E-value: 2.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 670 QSGIQRFVIRIHPVDRLPPELGSGCPLRmvVQESQLTPLRKRWLHYTDLDTDDRELHYTVTQPPtdtdeNHspaplGTLV 749
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTGLR--LWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGP-----SH-----GHLA 68
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 350534782 750 FTDNPSVVVTHFTQAQVNHHKIAYrppgQELGVAARVAQFQFQVED 795
Cdd:pfam16184 69 LKGAPGLPVTNFTQADIDSGLVVY----VHDGSESTSDGFTFQVTD 110
|
|
| Calx-beta |
pfam03160 |
Calx-beta domain; |
2237-2328 |
2.38e-14 |
|
Calx-beta domain;
Pssm-ID: 397326 [Multi-domain] Cd Length: 91 Bit Score: 70.74 E-value: 2.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2237 VIKFGETKFSVTEpsrpgESVVVKIPVIRQ-GDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFD 2315
Cdd:pfam03160 3 VIGFEPPTYQVSE-----NDGVAEVCVVRMsGTLRRTVVVPYRTEDGTATAGDDYEPVEGELVFGPGETEKCINVTIIDD 77
|
90
....*....|...
gi 350534782 2316 GVREMREAFTVHL 2328
Cdd:pfam03160 78 DVYEGDENFFVLL 90
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
1977-2210 |
2.43e-14 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 79.84 E-value: 2.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1977 GNKFPGANVTILTDKDDEPA--FYFGDTQHSVDESAGYVEVQVWRTGTDLTKPSSVTVRsrkTEPPSADAGTDYVGISRN 2054
Cdd:TIGR00845 380 ARKAVSMHEVATDDEENDPVskIFFEPGHYTCLENCGTVALTVVRRGGDLTNTVYVDYR---TEDGTANAGSDYEFTEGT 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2055 LDFAPGVSMQTVRVVILDDlgrPVLEGIEKFELVLRMP---------------MNAALGEPSKATVSINDsaSDLPKM-Q 2118
Cdd:TIGR00845 457 LVFKPGETQKEFRIGIIDD---DIFEEDEHFYVRLSNLrvgsedgileanhvsAVAQLASPNTATVTILD--DDHAGIfT 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2119 FKERVYTCSENDGHV-VAMIYRSGdlqHRSSVRC--YTRQGSAQV-MMDFEErpnTDISIVtFLPGESEKPCVLELMDDD 2194
Cdd:TIGR00845 532 FEEDVFHVSESIGIMeVKVLRTSG---ARGTVIVpyRTVEGTARGgGKDFED---TCGELE-FENDETEKTIRVKIVDDE 604
|
250
....*....|....*.
gi 350534782 2195 LYEDVEELRLVLGTPQ 2210
Cdd:TIGR00845 605 EYEKNDTFFIELGEPR 620
|
|
| Calx_beta |
smart00237 |
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ... |
2237-2328 |
1.16e-13 |
|
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)
Pssm-ID: 197594 [Multi-domain] Cd Length: 90 Bit Score: 68.82 E-value: 1.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2237 VIKFGETKFSVTEpsrpgESVVVKIPVIRQGDTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFDG 2316
Cdd:smart00237 3 SVGFEQPVYTVSE-----SDGEVEVCVVRTGGARGPVVVPYSTEDGTATAGSDYEPVPGELTFPPGETEKEIRIKIIDDD 77
|
90
....*....|..
gi 350534782 2317 VREMREAFTVHL 2328
Cdd:smart00237 78 IYEKDETFYVRL 89
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
910-1024 |
1.58e-13 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 69.17 E-value: 1.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 910 HVVPITLRVNVRPADREGAMSVLPAGtlesyLDVLENGATEVTANIIKGTYRDTDDLMLTFLLEGPPLYGEILVHGAP-- 987
Cdd:pfam16184 1 RSVPFTFNITIIPVNDEAPVLTTNTG-----LRLWEGSSRPITPDLLQAEDPDTPPEDLTYTVVQGPSHGHLALKGAPgl 75
|
90 100 110
....*....|....*....|....*....|....*...
gi 350534782 988 -AEQFTQRDILEGSVVYAHTSGEigllPKADSFNLSLS 1024
Cdd:pfam16184 76 pVTNFTQADIDSGLVVYVHDGSE----STSDGFTFQVT 109
|
|
| Calx_beta |
smart00237 |
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ... |
1997-2089 |
1.43e-12 |
|
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)
Pssm-ID: 197594 [Multi-domain] Cd Length: 90 Bit Score: 65.74 E-value: 1.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1997 FYFGDTQHSVDESAGYVEVQVWRTGtDLTKPSSVTVRsrkTEPPSADAGTDYVGISRNLDFAPGVSMQTVRVVILDDlgr 2076
Cdd:smart00237 4 VGFEQPVYTVSESDGEVEVCVVRTG-GARGPVVVPYS---TEDGTATAGSDYEPVPGELTFPPGETEKEIRIKIIDD--- 76
|
90
....*....|...
gi 350534782 2077 PVLEGIEKFELVL 2089
Cdd:smart00237 77 DIYEKDETFYVRL 89
|
|
| Calx-beta |
pfam03160 |
Calx-beta domain; |
1758-1845 |
5.89e-11 |
|
Calx-beta domain;
Pssm-ID: 397326 [Multi-domain] Cd Length: 91 Bit Score: 61.11 E-value: 5.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1758 ISFEKEYYLINEDSKFLDI-VLKRRGYLGETSFISISTRDGTAEKDKDFKGKAQkQVQFNPGQTRASWRVRILSDGEHEH 1836
Cdd:pfam03160 4 IGFEPPTYQVSENDGVAEVcVVRMSGTLRRTVVVPYRTEDGTATAGDDYEPVEG-ELVFGPGETEKCINVTIIDDDVYEG 82
|
....*....
gi 350534782 1837 SETFQVVLS 1845
Cdd:pfam03160 83 DENFFVLLS 91
|
|
| Calx_beta |
smart00237 |
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ... |
1869-1969 |
6.18e-11 |
|
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)
Pssm-ID: 197594 [Multi-domain] Cd Length: 90 Bit Score: 61.12 E-value: 6.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1869 STVFIPQSEYSVEEDVSELFIPIRRSGDISQELMVICYTQQGTATSTvrtsvlsySDYISRPedhsSVIRFDKDEREKMC 1948
Cdd:smart00237 2 GSVGFEQPVYTVSESDGEVEVCVVRTGGARGPVVVPYSTEDGTATAG--------SDYEPVP----GELTFPPGETEKEI 69
|
90 100
....*....|....*....|.
gi 350534782 1949 RVVVIDDSLYEEEETFQVLLS 1969
Cdd:smart00237 70 RIKIIDDDIYEKDETFYVRLS 90
|
|
| Calx_beta |
smart00237 |
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ... |
1758-1845 |
6.68e-11 |
|
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)
Pssm-ID: 197594 [Multi-domain] Cd Length: 90 Bit Score: 61.12 E-value: 6.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1758 ISFEKEYYLINEDSKFLDIVLKRRGYLGETSFISISTRDGTAEKDKDFKGKAQkQVQFNPGQTRASWRVRILSDGEHEHS 1837
Cdd:smart00237 4 VGFEQPVYTVSESDGEVEVCVVRTGGARGPVVVPYSTEDGTATAGSDYEPVPG-ELTFPPGETEKEIRIKIIDDDIYEKD 82
|
....*...
gi 350534782 1838 ETFQVVLS 1845
Cdd:smart00237 83 ETFYVRLS 90
|
|
| Calx-beta |
pfam03160 |
Calx-beta domain; |
1869-1969 |
2.52e-10 |
|
Calx-beta domain;
Pssm-ID: 397326 [Multi-domain] Cd Length: 91 Bit Score: 59.57 E-value: 2.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 1869 STVFIPQSEYSVEEDVSELFIPI-RRSGDISQELMVICYTQQGTATSTvrtsvlsySDYISRPEDhssvIRFDKDEREKM 1947
Cdd:pfam03160 2 GVIGFEPPTYQVSENDGVAEVCVvRMSGTLRRTVVVPYRTEDGTATAG--------DDYEPVEGE----LVFGPGETEKC 69
|
90 100
....*....|....*....|..
gi 350534782 1948 CRVVVIDDSLYEEEETFQVLLS 1969
Cdd:pfam03160 70 INVTIIDDDVYEGDENFFVLLS 91
|
|
| Calx-beta |
pfam03160 |
Calx-beta domain; |
2115-2207 |
3.51e-10 |
|
Calx-beta domain;
Pssm-ID: 397326 [Multi-domain] Cd Length: 91 Bit Score: 58.80 E-value: 3.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2115 PKMQFKERVYTCSENDGHV-VAMIYRSGDLQHRSSVRCYTRQGSAQVMMDFEERPNTdisiVTFLPGESEKPCVLELMDD 2193
Cdd:pfam03160 2 GVIGFEPPTYQVSENDGVAeVCVVRMSGTLRRTVVVPYRTEDGTATAGDDYEPVEGE----LVFGPGETEKCINVTIIDD 77
|
90
....*....|....
gi 350534782 2194 DLYEDVEELRLVLG 2207
Cdd:pfam03160 78 DVYEGDENFFVLLS 91
|
|
| Calx_beta |
smart00237 |
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin ... |
2116-2207 |
4.06e-10 |
|
Domains in Na-Ca exchangers and integrin-beta4; Domain in Na-Ca exchangers and integrin subunit beta4 (and some cyanobacterial proteins)
Pssm-ID: 197594 [Multi-domain] Cd Length: 90 Bit Score: 58.81 E-value: 4.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2116 KMQFKERVYTCSENDGHVVAMIYRSGDLQHRSSVRCYTRQGSAQVMMDFEERPNTdisiVTFLPGESEKPCVLELMDDDL 2195
Cdd:smart00237 3 SVGFEQPVYTVSESDGEVEVCVVRTGGARGPVVVPYSTEDGTATAGSDYEPVPGE----LTFPPGETEKEIRIKIIDDDI 78
|
90
....*....|..
gi 350534782 2196 YEDVEELRLVLG 2207
Cdd:smart00237 79 YEKDETFYVRLS 90
|
|
| Cadherin_3 |
pfam16184 |
Cadherin-like; |
327-387 |
8.41e-09 |
|
Cadherin-like;
Pssm-ID: 465048 [Multi-domain] Cd Length: 111 Bit Score: 55.69 E-value: 8.41e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 350534782 327 TALTPDMLAAEDAESNPDLLIFNLTSafQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQ 387
Cdd:pfam16184 35 RPITPDLLQAEDPDTPPEDLTYTVVQ--GPSHGHLALKGAPGLPVTNFTQADIDSGLVVYV 93
|
|
| caca |
TIGR00845 |
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of ... |
2259-2376 |
1.15e-07 |
|
sodium/calcium exchanger 1; The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other]
Pssm-ID: 273296 [Multi-domain] Cd Length: 928 Bit Score: 57.88 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 2259 VKIPVIRQG-DTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHTVEIEVIFDGVREMREAFTVHLK----PDEN 2333
Cdd:TIGR00845 418 VALTVVRRGgDLTNTVYVDYRTEDGTANAGSDYEFTEGTLVFKPGETQKEFRIGIIDDDIFEEDEHFYVRLSnlrvGSED 497
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 350534782 2334 MVAETQTTKAIVYIEeinsmadvtfpsVPHIVSLMVYDDTFKG 2376
Cdd:TIGR00845 498 GILEANHVSAVAQLA------------SPNTATVTILDDDHAG 528
|
|
| Big_9 |
pfam17963 |
Bacterial Ig domain; This entry represents a wide variety of bacterial Ig domains. |
802-907 |
1.10e-04 |
|
Bacterial Ig domain; This entry represents a wide variety of bacterial Ig domains.
Pssm-ID: 465590 [Multi-domain] Cd Length: 90 Bit Score: 43.48 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 350534782 802 PGTFTLYLQPVdNQPPEIVNTGFTVEEKGhhVLreteLHVSDVDTD---VAHISFTLTQAPKHGHLQISGrplhvggqfr 878
Cdd:pfam17963 1 TATVTVTVTPV-NDAPVAVDDSVTVTEDT--VL----ANDSDPDGDpltITSLTVTIVTAPANGTVTVNA---------- 63
|
90 100
....*....|....*....|....*....
gi 350534782 879 ledikQGRISYLNSGDESLTDSCSLEVSD 907
Cdd:pfam17963 64 -----DGTLTYTPNAGFSGTDSFTYTVSD 87
|
|
| |
