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Conserved domains on  [gi|348041409|ref|NP_001231697|]
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protein FAM110A isoform 1 [Rattus norvegicus]

Protein Classification

FAM110_N and FAM110_C domain-containing protein( domain architecture ID 10342682)

FAM110_N and FAM110_C domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAM110_C pfam14160
Centrosome-associated C terminus; This is the C-terminus of a family of proteins that ...
 182-288 6.36e-40

Centrosome-associated C terminus; This is the C-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


:

Pssm-ID: 464094  Cd Length: 113  Bit Score: 135.23  E-value: 6.36e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041409  182 PPGLQRSKSDLSERFSRAAADLERFFNFCGLDPEEARGLGVAHL--ARASSDIV---SLAGPSAGPCSSEGGCSRRSSAT 256
Cdd:pfam14160   1 RPSLHRSKSDLSSRYSLALSELERFFNYCGLDPEVVEPLGRENFtsAGASSDSSrfrSVSGSSSESGFSRRSGDSSDGTG 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 348041409  257 VEERTL-ERVPYGVSVIERNARVIKWLYGLRQA 288
Cdd:pfam14160  81 LDEEELaERVPSGVSVIERNARVIKWLYGCKKA 113
FAM110_N super family cl16669
Centrosome-associated N terminus; This is the N-terminus of a family of proteins that ...
 4-104 3.55e-38

Centrosome-associated N terminus; This is the N-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


The actual alignment was detected with superfamily member pfam14161:

Pssm-ID: 464095  Cd Length: 107  Bit Score: 130.69  E-value: 3.55e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041409    4 DTLSPGAPTTPALPFRLRTKVPGYLlPRPADGGARKPSAVERLEADKAKYVKSLRVANTRQEPVQPPLARQPLFSPG-SR 82
Cdd:pfam14161   1 KAVGPGTPFTSAMPFRILNKGPDYF-RRQAEPGAKKLSAVERLEADKAKYVKSQEVANTRQEPVKPPLLAKPLVSPGlKR 79

                          90       100
                  ....*....|....*....|....*...
gi 348041409   83 GPVLTPSRRVLPCS------GRRPQLDL 104
Cdd:pfam14161  80 GPGLTPGRRGPPCParsdacARRENLNL 107
 
Name Accession Description Interval E-value
FAM110_C pfam14160
Centrosome-associated C terminus; This is the C-terminus of a family of proteins that ...
 182-288 6.36e-40

Centrosome-associated C terminus; This is the C-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


Pssm-ID: 464094  Cd Length: 113  Bit Score: 135.23  E-value: 6.36e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041409  182 PPGLQRSKSDLSERFSRAAADLERFFNFCGLDPEEARGLGVAHL--ARASSDIV---SLAGPSAGPCSSEGGCSRRSSAT 256
Cdd:pfam14160   1 RPSLHRSKSDLSSRYSLALSELERFFNYCGLDPEVVEPLGRENFtsAGASSDSSrfrSVSGSSSESGFSRRSGDSSDGTG 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 348041409  257 VEERTL-ERVPYGVSVIERNARVIKWLYGLRQA 288
Cdd:pfam14160  81 LDEEELaERVPSGVSVIERNARVIKWLYGCKKA 113
FAM110_N pfam14161
Centrosome-associated N terminus; This is the N-terminus of a family of proteins that ...
 4-104 3.55e-38

Centrosome-associated N terminus; This is the N-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


Pssm-ID: 464095  Cd Length: 107  Bit Score: 130.69  E-value: 3.55e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041409    4 DTLSPGAPTTPALPFRLRTKVPGYLlPRPADGGARKPSAVERLEADKAKYVKSLRVANTRQEPVQPPLARQPLFSPG-SR 82
Cdd:pfam14161   1 KAVGPGTPFTSAMPFRILNKGPDYF-RRQAEPGAKKLSAVERLEADKAKYVKSQEVANTRQEPVKPPLLAKPLVSPGlKR 79

                          90       100
                  ....*....|....*....|....*...
gi 348041409   83 GPVLTPSRRVLPCS------GRRPQLDL 104
Cdd:pfam14161  80 GPGLTPGRRGPPCParsdacARRENLNL 107
 
Name Accession Description Interval E-value
FAM110_C pfam14160
Centrosome-associated C terminus; This is the C-terminus of a family of proteins that ...
 182-288 6.36e-40

Centrosome-associated C terminus; This is the C-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


Pssm-ID: 464094  Cd Length: 113  Bit Score: 135.23  E-value: 6.36e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041409  182 PPGLQRSKSDLSERFSRAAADLERFFNFCGLDPEEARGLGVAHL--ARASSDIV---SLAGPSAGPCSSEGGCSRRSSAT 256
Cdd:pfam14160   1 RPSLHRSKSDLSSRYSLALSELERFFNYCGLDPEVVEPLGRENFtsAGASSDSSrfrSVSGSSSESGFSRRSGDSSDGTG 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 348041409  257 VEERTL-ERVPYGVSVIERNARVIKWLYGLRQA 288
Cdd:pfam14160  81 LDEEELaERVPSGVSVIERNARVIKWLYGCKKA 113
FAM110_N pfam14161
Centrosome-associated N terminus; This is the N-terminus of a family of proteins that ...
 4-104 3.55e-38

Centrosome-associated N terminus; This is the N-terminus of a family of proteins that colocalize with the centrosome/microtubule organization centre in interphase and at the spindle poles in mitosis.


Pssm-ID: 464095  Cd Length: 107  Bit Score: 130.69  E-value: 3.55e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 348041409    4 DTLSPGAPTTPALPFRLRTKVPGYLlPRPADGGARKPSAVERLEADKAKYVKSLRVANTRQEPVQPPLARQPLFSPG-SR 82
Cdd:pfam14161   1 KAVGPGTPFTSAMPFRILNKGPDYF-RRQAEPGAKKLSAVERLEADKAKYVKSQEVANTRQEPVKPPLLAKPLVSPGlKR 79

                          90       100
                  ....*....|....*....|....*...
gi 348041409   83 GPVLTPSRRVLPCS------GRRPQLDL 104
Cdd:pfam14161  80 GPGLTPGRRGPPCParsdacARRENLNL 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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