NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|320544805|ref|NP_001188757|]
View 

junctophilin, isoform D [Drosophila melanogaster]

Protein Classification

MORN repeat-containing protein( domain architecture ID 10494539)

membrane-occupation-and-recognition-nexus (MORN) repeat-containing protein may be involved in protein-protein interactions

PubMed:  33296386|35568981

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
49-194 8.24e-24

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 102.34  E-value: 8.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPkHQGAYAGAWNYG-FEVSGSYIWPSGSHYEGQWQNGRRHGLGveqigrqI 127
Cdd:COG4642   139 GGIYTFPNGDVYEGEFKNGKPHGQGTLTYA-DGDRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHGQG-------T 210

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 320544805  128 YRgewSKDGHKgrygvrestvstakYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYGIRTSA 194
Cdd:COG4642   211 YT---YADGDR--------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260
PLN03185 super family cl33654
phosphatidylinositol phosphate kinase; Provisional
 84-384 6.25e-13

phosphatidylinositol phosphate kinase; Provisional


The actual alignment was detected with superfamily member PLN03185:

Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 72.94  E-value: 6.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   84 YAGAWNYGF-EVSGSYIWPSGSHYEGQWQNGRRHGLGveqigrqiyRGEWSkdghkgrygvrestvSTAKYEGTWNEGYQ 162
Cdd:PLN03185   11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---------KISWP---------------SGATYEGEFSGGYM 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  163 DGSGCETYADGGKYQGQWQEGKRHGYGirtsapfglashhrrknlhaslsslrsgengnaakmvekaeeirggfvltaks 242
Cdd:PLN03185   67 HGSGTYTGTDGTTYKGRWRLNLKHGLG----------------------------------------------------- 93

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  243 dklpvrrnsltdktgkkgflmnlkmRKQRSTGDlekrgtiasgsirstMSSASWISTGSEQSNLTTKSNHTEsnasftme 322
Cdd:PLN03185   94 -------------------------YQRYPNGD---------------VFEGSWIQGLQEGPGKYTWANGNV-------- 125

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 320544805  323 deqldptvvetYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKY 384
Cdd:PLN03185  126 -----------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTW 176
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
49-194 8.24e-24

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 102.34  E-value: 8.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPkHQGAYAGAWNYG-FEVSGSYIWPSGSHYEGQWQNGRRHGLGveqigrqI 127
Cdd:COG4642   139 GGIYTFPNGDVYEGEFKNGKPHGQGTLTYA-DGDRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHGQG-------T 210

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 320544805  128 YRgewSKDGHKgrygvrestvstakYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYGIRTSA 194
Cdd:COG4642   211 YT---YADGDR--------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 46-192 1.03e-18

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 91.82  E-value: 1.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   46 PINGGRFDFEDGGTYCGGWDEGKAHGHGVC---TGPKHQGAYAGAWNYGfevSGSYIWPSGSHYEGQWQNGRRHGLGVEQ 122
Cdd:PLN03185   20 PEGPGKYLWSDGCMYEGEWRRGMRHGNGKIswpSGATYEGEFSGGYMHG---SGTYTGTDGTTYKGRWRLNLKHGLGYQR 96

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320544805  123 IGR-QIYRGEWSKDGHKG--RYgvreSTVSTAKYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYGIRT 192
Cdd:PLN03185   97 YPNgDVFEGSWIQGLQEGpgKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYT 165
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 84-384 6.25e-13

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 72.94  E-value: 6.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   84 YAGAWNYGF-EVSGSYIWPSGSHYEGQWQNGRRHGLGveqigrqiyRGEWSkdghkgrygvrestvSTAKYEGTWNEGYQ 162
Cdd:PLN03185   11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---------KISWP---------------SGATYEGEFSGGYM 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  163 DGSGCETYADGGKYQGQWQEGKRHGYGirtsapfglashhrrknlhaslsslrsgengnaakmvekaeeirggfvltaks 242
Cdd:PLN03185   67 HGSGTYTGTDGTTYKGRWRLNLKHGLG----------------------------------------------------- 93

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  243 dklpvrrnsltdktgkkgflmnlkmRKQRSTGDlekrgtiasgsirstMSSASWISTGSEQSNLTTKSNHTEsnasftme 322
Cdd:PLN03185   94 -------------------------YQRYPNGD---------------VFEGSWIQGLQEGPGKYTWANGNV-------- 125

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 320544805  323 deqldptvvetYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKY 384
Cdd:PLN03185  126 -----------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTW 176
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 357-379 4.20e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 41.24  E-value: 4.20e-05
                           10        20
                   ....*....|....*....|...
gi 320544805   357 YEGEWYNNRKHGYGVTTFRDGTV 379
Cdd:pfam02493    1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
356-376 4.54e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.09  E-value: 4.54e-04
                            10        20
                    ....*....|....*....|.
gi 320544805    356 KYEGEWYNNRKHGYGVTTFRD 376
Cdd:smart00698    2 RYEGEWRNGKRHGRGVYTYAN 22
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
175-194 9.10e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.32  E-value: 9.10e-04
                            10        20
                    ....*....|....*....|
gi 320544805    175 KYQGQWQEGKRHGYGIRTSA 194
Cdd:smart00698    2 RYEGEWRNGKRHGRGVYTYA 21
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
336-395 9.25e-04

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 41.21  E-value: 9.25e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 320544805  336 GEWKKDKRcgHGVAER--SDG-LKYEGEWYNNRKHGYGVTTFRDGTV-EEGKYKNNILITSQKK 395
Cdd:COG2849    83 GTYKNGKL--EGEWKEyyENGkLKSEGNYKNGKLHGEWKEYYENGKLkEEGNYKNGKKDGVWKY 144
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 176-194 5.94e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 35.08  E-value: 5.94e-03
                           10
                   ....*....|....*....
gi 320544805   176 YQGQWQEGKRHGYGIRTSA 194
Cdd:pfam02493    1 YEGEWKNGKRHGKGVYTWP 19
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
49-194 8.24e-24

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 102.34  E-value: 8.24e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   49 GGRFDFEDGGTYCGGWDEGKAHGHGVCTGPkHQGAYAGAWNYG-FEVSGSYIWPSGSHYEGQWQNGRRHGLGveqigrqI 127
Cdd:COG4642   139 GGIYTFPNGDVYEGEFKNGKPHGQGTLTYA-DGDRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHGQG-------T 210

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 320544805  128 YRgewSKDGHKgrygvrestvstakYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYGIRTSA 194
Cdd:COG4642   211 YT---YADGDR--------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
48-386 1.34e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.57  E-value: 1.34e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   48 NGGRFDFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPSGSHYEGQWQNGRRHGLGVEQigrqi 127
Cdd:COG4642    92 GGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT----- 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  128 yrgewSKDGhkgrygvrestvstAKYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYGIRTSApfglashhrrknl 207
Cdd:COG4642   167 -----YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTYA------------- 214

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  208 haslsslrsgeNGnaakmvekaeeirggfvltaksdklpvrrnsltdktgkkgflmnlkmrkqrstgdlekrgtiasgsi 287
Cdd:COG4642   215 -----------DG------------------------------------------------------------------- 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  288 rstmssaswistgseqsnlttksnhtesnasftmedeqldptvvETYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKH 367
Cdd:COG4642   217 --------------------------------------------DRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRH 252

                         330
                  ....*....|....*....
gi 320544805  368 GYGVTTFRDGTVEEGKYKN 386
Cdd:COG4642   253 GQGTMTYADGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
45-389 9.13e-20

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 90.40  E-value: 9.13e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   45 GPINGGRFDFEDGGTYCGGWDEGKAH-GHGVCTGPKHQGAYAGAWNYGFEVSGSYIWPSGSHYEGQWQNGRRHGLGVEQI 123
Cdd:COG4642    30 GGEGGGGLGTLPGGGGYGGGADGGGGgGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKK 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  124 GRQIYRGEWSKDGHKGRYGVREST-----------VSTAKYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYGIRT 192
Cdd:COG4642   110 GGGGGGGGVLEGDDGGGYGGGTADggrggggiytfPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLT 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  193 SApfglashhrrknlhaslsslrsgeNGNaakmvekaeeirggfvltaksdklpvrrnsltdktgkkgflmnlkmrkqrs 272
Cdd:COG4642   190 YA------------------------NGD--------------------------------------------------- 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  273 tgdlekrgtiasgsirstmssaswistgseqsnlttksnhtesnasftmedeqldptvveTYMGEWKKDKRCGHGVAERS 352
Cdd:COG4642   195 ------------------------------------------------------------VYEGEFKNGQRHGQGTYTYA 214

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 320544805  353 DGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNIL 389
Cdd:COG4642   215 DGDRYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKR 251
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 46-192 1.03e-18

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 91.82  E-value: 1.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   46 PINGGRFDFEDGGTYCGGWDEGKAHGHGVC---TGPKHQGAYAGAWNYGfevSGSYIWPSGSHYEGQWQNGRRHGLGVEQ 122
Cdd:PLN03185   20 PEGPGKYLWSDGCMYEGEWRRGMRHGNGKIswpSGATYEGEFSGGYMHG---SGTYTGTDGTTYKGRWRLNLKHGLGYQR 96

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 320544805  123 IGR-QIYRGEWSKDGHKG--RYgvreSTVSTAKYEGTWNEGYQDGSGCETYADGGKYQGQWQEGKRHGYGIRT 192
Cdd:PLN03185   97 YPNgDVFEGSWIQGLQEGpgKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYT 165
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 84-384 6.25e-13

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 72.94  E-value: 6.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   84 YAGAWNYGF-EVSGSYIWPSGSHYEGQWQNGRRHGLGveqigrqiyRGEWSkdghkgrygvrestvSTAKYEGTWNEGYQ 162
Cdd:PLN03185   11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHGNG---------KISWP---------------SGATYEGEFSGGYM 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  163 DGSGCETYADGGKYQGQWQEGKRHGYGirtsapfglashhrrknlhaslsslrsgengnaakmvekaeeirggfvltaks 242
Cdd:PLN03185   67 HGSGTYTGTDGTTYKGRWRLNLKHGLG----------------------------------------------------- 93

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805  243 dklpvrrnsltdktgkkgflmnlkmRKQRSTGDlekrgtiasgsirstMSSASWISTGSEQSNLTTKSNHTEsnasftme 322
Cdd:PLN03185   94 -------------------------YQRYPNGD---------------VFEGSWIQGLQEGPGKYTWANGNV-------- 125

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 320544805  323 deqldptvvetYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKY 384
Cdd:PLN03185  126 -----------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTW 176
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 357-379 4.20e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 41.24  E-value: 4.20e-05
                           10        20
                   ....*....|....*....|...
gi 320544805   357 YEGEWYNNRKHGYGVTTFRDGTV 379
Cdd:pfam02493    1 YEGEWKNGKRHGKGVYTWPDGDR 23
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
86-188 4.30e-05

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 45.06  E-value: 4.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 320544805   86 GAWNYGFEVSGSYIW--PSGS-HYEGQWQNGRRHGLGVeqigrqiyrgEWSKDGHKgrygvrestvstaKYEGTWNEGYQ 162
Cdd:COG2849    58 GLGKYKKGKLGEWKTyyPNGQlKSEGTYKNGKLEGEWK----------EYYENGKL-------------KSEGNYKNGKL 114

                          90       100
                  ....*....|....*....|....*..
gi 320544805  163 DGSGCETYADGG-KYQGQWQEGKRHGY 188
Cdd:COG2849   115 HGEWKEYYENGKlKEEGNYKNGKKDGV 141
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
356-376 4.54e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.09  E-value: 4.54e-04
                            10        20
                    ....*....|....*....|.
gi 320544805    356 KYEGEWYNNRKHGYGVTTFRD 376
Cdd:smart00698    2 RYEGEWRNGKRHGRGVYTYAN 22
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 333-388 5.56e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 44.05  E-value: 5.56e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 320544805  333 TYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNI 388
Cdd:PLN03185   33 MYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNL 88
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
175-194 9.10e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.32  E-value: 9.10e-04
                            10        20
                    ....*....|....*....|
gi 320544805    175 KYQGQWQEGKRHGYGIRTSA 194
Cdd:smart00698    2 RYEGEWRNGKRHGRGVYTYA 21
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
336-395 9.25e-04

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 41.21  E-value: 9.25e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 320544805  336 GEWKKDKRcgHGVAER--SDG-LKYEGEWYNNRKHGYGVTTFRDGTV-EEGKYKNNILITSQKK 395
Cdd:COG2849    83 GTYKNGKL--EGEWKEyyENGkLKSEGNYKNGKLHGEWKEYYENGKLkEEGNYKNGKKDGVWKY 144
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
104-120 2.95e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 35.78  E-value: 2.95e-03
                            10
                    ....*....|....*..
gi 320544805    104 SHYEGQWQNGRRHGLGV 120
Cdd:smart00698    1 DRYEGEWRNGKRHGRGV 17
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
336-390 3.17e-03

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 39.67  E-value: 3.17e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 320544805  336 GEWKKDKRcgHGVAER--SDG-LKYEGEWYNNRKHGYGVTTFRDGT-VEEGKYKNNILI 390
Cdd:COG2849   107 GNYKNGKL--HGEWKEyyENGkLKEEGNYKNGKKDGVWKYYDENGKlVKEEEYKNGKKV 163
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 176-194 5.94e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 35.08  E-value: 5.94e-03
                           10
                   ....*....|....*....
gi 320544805   176 YQGQWQEGKRHGYGIRTSA 194
Cdd:pfam02493    1 YEGEWKNGKRHGKGVYTWP 19
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 106-122 6.05e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 35.08  E-value: 6.05e-03
                           10
                   ....*....|....*..
gi 320544805   106 YEGQWQNGRRHGLGVEQ 122
Cdd:pfam02493    1 YEGEWKNGKRHGKGVYT 17
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH