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Conserved domains on  [gi|2106241829|ref|NP_001188397|]
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serum paraoxonase/arylesterase 2 [Gallus gallus]

Protein Classification

strictosidine synthase family protein( domain architecture ID 10484254)

strictosidine synthase family protein with similarity to strictosidine synthase that catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Arylesterase pfam01731
Arylesterase; This family consists of arylesterases (Also known as serum paraoxonase) EC:3.1.1. ...
 167-252 8.13e-47

Arylesterase; This family consists of arylesterases (Also known as serum paraoxonase) EC:3.1.1.2. These enzymes hydrolyse organophosphorus esters such as paraoxon and are found in the liver and blood. They confer resistance to organophosphate toxicity. Human arylesterase (PON1) is associated with HDL and may protect against LDL oxidation.


:

Pssm-ID: 334656  Cd Length: 86  Bit Score: 153.77  E-value: 8.13e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 167 NDVVAVGPDSFYATNDHYFSDFILMFLEMYLGLTWSNVVYYSPKEVKEVAAGFYSANGINISPDKKYIYIADILDHNVHV 246
Cdd:pfam01731   1 NDIVAVGPDSFYATNDHYFGDPFLQNLEMYLGLIWTGVVYYSPSEVKVVASGFSFANGINYSPDKKYIYVASSLRHSIHV 80


                  ....*.
gi 2106241829 247 MEKHAD 252
Cdd:pfam01731  81 MKKHAN 86
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 106-287 3.42e-11

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 62.99  E-value: 3.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 106 FDLGSFNPHGIstYIDKDDTvyLFVVNHPHQkstveLFKFMEDDNSLVHLKTIRHDLLTSVNDVVaVGPD-SFYATNdhy 184
Cdd:COG3386    44 FAEPSGRPNGL--AFDPDGR--LLVADHGRG-----LVRFDPADGEVTVLADEYGKPLNRPNDGV-VDPDgRLYFTD--- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 185 fsdfilmfleMYLGLTWSNVVYYSPK-EVKEVAAGFYSANGINISPDKKYIYIADILDHNVHVMEKHADWNLTHVKTL-- 261
Cdd:COG3386   111 ----------MGEYLPTGALYRVDPDgSLRVLADGLTFPNGIAFSPDGRTLYVADTGAGRIYRFDLDADGTLGNRRVFad 180

                         170       180
                  ....*....|....*....|....*...
gi 2106241829 262 --QLDTLADNLSVDPDtGDIWTGCHPNG 287
Cdd:COG3386   181 lpDGPGGPDGLAVDAD-GNLWVALWGGG 207
 
Name Accession Description Interval E-value
Arylesterase pfam01731
Arylesterase; This family consists of arylesterases (Also known as serum paraoxonase) EC:3.1.1. ...
 167-252 8.13e-47

Arylesterase; This family consists of arylesterases (Also known as serum paraoxonase) EC:3.1.1.2. These enzymes hydrolyse organophosphorus esters such as paraoxon and are found in the liver and blood. They confer resistance to organophosphate toxicity. Human arylesterase (PON1) is associated with HDL and may protect against LDL oxidation.


Pssm-ID: 334656  Cd Length: 86  Bit Score: 153.77  E-value: 8.13e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 167 NDVVAVGPDSFYATNDHYFSDFILMFLEMYLGLTWSNVVYYSPKEVKEVAAGFYSANGINISPDKKYIYIADILDHNVHV 246
Cdd:pfam01731   1 NDIVAVGPDSFYATNDHYFGDPFLQNLEMYLGLIWTGVVYYSPSEVKVVASGFSFANGINYSPDKKYIYVASSLRHSIHV 80


                  ....*.
gi 2106241829 247 MEKHAD 252
Cdd:pfam01731  81 MKKHAN 86
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 106-287 3.42e-11

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 62.99  E-value: 3.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 106 FDLGSFNPHGIstYIDKDDTvyLFVVNHPHQkstveLFKFMEDDNSLVHLKTIRHDLLTSVNDVVaVGPD-SFYATNdhy 184
Cdd:COG3386    44 FAEPSGRPNGL--AFDPDGR--LLVADHGRG-----LVRFDPADGEVTVLADEYGKPLNRPNDGV-VDPDgRLYFTD--- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 185 fsdfilmfleMYLGLTWSNVVYYSPK-EVKEVAAGFYSANGINISPDKKYIYIADILDHNVHVMEKHADWNLTHVKTL-- 261
Cdd:COG3386   111 ----------MGEYLPTGALYRVDPDgSLRVLADGLTFPNGIAFSPDGRTLYVADTGAGRIYRFDLDADGTLGNRRVFad 180

                         170       180
                  ....*....|....*....|....*...
gi 2106241829 262 --QLDTLADNLSVDPDtGDIWTGCHPNG 287
Cdd:COG3386   181 lpDGPGGPDGLAVDAD-GNLWVALWGGG 207
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
194-287 3.29e-04

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 41.60  E-value: 3.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 194 EMYLGLTWSNVVY----YSPKEVKEVAAGFYsANGINISPDKKYIYIADILDHNVHVMEKHADW-NLTHVKTLQLDTLAD 268
Cdd:COG3391   123 RLYVADSGNGRVSvidtATGKVVATIPVGAG-PHGIAVDPDGKRLYVANSGSNTVSVIVSVIDTaTGKVVATIPVGGGPV 201

                          90
                  ....*....|....*....
gi 2106241829 269 NLSVDPDTGDIWTGCHPNG 287
Cdd:COG3391   202 GVAVSPDGRRLYVANRGSN 220
 
Name Accession Description Interval E-value
Arylesterase pfam01731
Arylesterase; This family consists of arylesterases (Also known as serum paraoxonase) EC:3.1.1. ...
 167-252 8.13e-47

Arylesterase; This family consists of arylesterases (Also known as serum paraoxonase) EC:3.1.1.2. These enzymes hydrolyse organophosphorus esters such as paraoxon and are found in the liver and blood. They confer resistance to organophosphate toxicity. Human arylesterase (PON1) is associated with HDL and may protect against LDL oxidation.


Pssm-ID: 334656  Cd Length: 86  Bit Score: 153.77  E-value: 8.13e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 167 NDVVAVGPDSFYATNDHYFSDFILMFLEMYLGLTWSNVVYYSPKEVKEVAAGFYSANGINISPDKKYIYIADILDHNVHV 246
Cdd:pfam01731   1 NDIVAVGPDSFYATNDHYFGDPFLQNLEMYLGLIWTGVVYYSPSEVKVVASGFSFANGINYSPDKKYIYVASSLRHSIHV 80


                  ....*.
gi 2106241829 247 MEKHAD 252
Cdd:pfam01731  81 MKKHAN 86
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 106-287 3.42e-11

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 62.99  E-value: 3.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 106 FDLGSFNPHGIstYIDKDDTvyLFVVNHPHQkstveLFKFMEDDNSLVHLKTIRHDLLTSVNDVVaVGPD-SFYATNdhy 184
Cdd:COG3386    44 FAEPSGRPNGL--AFDPDGR--LLVADHGRG-----LVRFDPADGEVTVLADEYGKPLNRPNDGV-VDPDgRLYFTD--- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 185 fsdfilmfleMYLGLTWSNVVYYSPK-EVKEVAAGFYSANGINISPDKKYIYIADILDHNVHVMEKHADWNLTHVKTL-- 261
Cdd:COG3386   111 ----------MGEYLPTGALYRVDPDgSLRVLADGLTFPNGIAFSPDGRTLYVADTGAGRIYRFDLDADGTLGNRRVFad 180

                         170       180
                  ....*....|....*....|....*...
gi 2106241829 262 --QLDTLADNLSVDPDtGDIWTGCHPNG 287
Cdd:COG3386   181 lpDGPGGPDGLAVDAD-GNLWVALWGGG 207
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
194-287 3.29e-04

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 41.60  E-value: 3.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2106241829 194 EMYLGLTWSNVVY----YSPKEVKEVAAGFYsANGINISPDKKYIYIADILDHNVHVMEKHADW-NLTHVKTLQLDTLAD 268
Cdd:COG3391   123 RLYVADSGNGRVSvidtATGKVVATIPVGAG-PHGIAVDPDGKRLYVANSGSNTVSVIVSVIDTaTGKVVATIPVGGGPV 201

                          90
                  ....*....|....*....
gi 2106241829 269 NLSVDPDTGDIWTGCHPNG 287
Cdd:COG3391   202 GVAVSPDGRRLYVANRGSN 220
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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