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Conserved domains on  [gi|334182416|ref|NP_001184947|]
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glucose-6-phosphate dehydrogenase 4 [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02333 super family cl47074
glucose-6-phosphate 1-dehydrogenase
 14-634 0e+00

glucose-6-phosphate 1-dehydrogenase


The actual alignment was detected with superfamily member PLN02333:

Pssm-ID: 215191 [Multi-domain]  Cd Length: 604  Bit Score: 613.52  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  14 ATAPSSSVCSCHLAASFSNFPVSSrdysfSRSGSLVLNGggsnlcrrfcglklwilKSLNRRQGNNRKHQPVnELTTHSK 93
Cdd:PLN02333   2 ATLSSSHSCPYARSYSYSLSPSSS-----SSHSSVVDPH-----------------RSLSFLSAIPQGLNPA-KLCVRSQ 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  94 HTF-----LSDDERGFAEETRAEDLRPEENILGTDLNDGFHNVGDLPPVSKQLSDDLSDVRrraslcIAVVGATGELARG 168
Cdd:PLN02333  59 RNSyqnvvLMQDGAVATPSNPVENDSSFKKLKDGLLSSIPSSEEDKVVAEFDGNKDESTVS------ITVVGASGDLAKK 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 169 KIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENCGGKMDAFQSRTYYINGGYNNRDGMSRLA 248
Cdd:PLN02333 133 KIFPALFALYYEGCLPEHFTIFGYARSKMTDAELRNMVSKTLTCRIDKRENCGEKMEEFLKRCFYHSGQYDSQEHFAELD 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 249 ERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQLTKSLLSKFEEKQIYRIDHM 328
Cdd:PLN02333 213 KKLKEHEGGRVSNRLFYLSIPPNIFVDAVKCASSSASSVNGWTRVIVEKPFGRDSESSAALTKSLKQYLEEDQIFRIDHY 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 329 LGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAQTEK--FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGE 406
Cdd:PLN02333 293 LGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRggYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAE 372

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 407 DIRNEKVNlyckeqnrlmVLRSIRKIDPRDVILGQYKSSSR---------DKNGVILNGVDPTYCAAALYIDNARWDGVP 477
Cdd:PLN02333 373 DIRNEKVK----------VLRSMRPIQLEDVVIGQYKSHTKggvtypaytDDKTVPKGSLTPTFAAAALFIDNARWDGVP 442

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 478 FLVRVGTGLIKHRVEIHVQFRHVPGNLYRENIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDR 557
Cdd:PLN02333 443 FLMKAGKALHTKSAEIRVQFRHVPGNLYNRNFGTDLDQATNELVIRVQPDEAIYLKINNKVPGLGMRLDRSNLNLLYAAR 522

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334182416 558 YKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHGVPWAD 634
Cdd:PLN02333 523 YSKEIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPVGAHYLAARYKVRWGD 599
 
Name Accession Description Interval E-value
PLN02333 PLN02333
glucose-6-phosphate 1-dehydrogenase
 14-634 0e+00

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215191 [Multi-domain]  Cd Length: 604  Bit Score: 613.52  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  14 ATAPSSSVCSCHLAASFSNFPVSSrdysfSRSGSLVLNGggsnlcrrfcglklwilKSLNRRQGNNRKHQPVnELTTHSK 93
Cdd:PLN02333   2 ATLSSSHSCPYARSYSYSLSPSSS-----SSHSSVVDPH-----------------RSLSFLSAIPQGLNPA-KLCVRSQ 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  94 HTF-----LSDDERGFAEETRAEDLRPEENILGTDLNDGFHNVGDLPPVSKQLSDDLSDVRrraslcIAVVGATGELARG 168
Cdd:PLN02333  59 RNSyqnvvLMQDGAVATPSNPVENDSSFKKLKDGLLSSIPSSEEDKVVAEFDGNKDESTVS------ITVVGASGDLAKK 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 169 KIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENCGGKMDAFQSRTYYINGGYNNRDGMSRLA 248
Cdd:PLN02333 133 KIFPALFALYYEGCLPEHFTIFGYARSKMTDAELRNMVSKTLTCRIDKRENCGEKMEEFLKRCFYHSGQYDSQEHFAELD 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 249 ERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQLTKSLLSKFEEKQIYRIDHM 328
Cdd:PLN02333 213 KKLKEHEGGRVSNRLFYLSIPPNIFVDAVKCASSSASSVNGWTRVIVEKPFGRDSESSAALTKSLKQYLEEDQIFRIDHY 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 329 LGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAQTEK--FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGE 406
Cdd:PLN02333 293 LGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRggYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAE 372

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 407 DIRNEKVNlyckeqnrlmVLRSIRKIDPRDVILGQYKSSSR---------DKNGVILNGVDPTYCAAALYIDNARWDGVP 477
Cdd:PLN02333 373 DIRNEKVK----------VLRSMRPIQLEDVVIGQYKSHTKggvtypaytDDKTVPKGSLTPTFAAAALFIDNARWDGVP 442

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 478 FLVRVGTGLIKHRVEIHVQFRHVPGNLYRENIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDR 557
Cdd:PLN02333 443 FLMKAGKALHTKSAEIRVQFRHVPGNLYNRNFGTDLDQATNELVIRVQPDEAIYLKINNKVPGLGMRLDRSNLNLLYAAR 522

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334182416 558 YKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHGVPWAD 634
Cdd:PLN02333 523 YSKEIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPVGAHYLAARYKVRWGD 599
zwf TIGR00871
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ...
 152-632 3.43e-156

glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273312 [Multi-domain]  Cd Length: 487  Bit Score: 458.32  E-value: 3.43e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  152 ASLCIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTL--TCRVDHQEncggKMDAFQS 229
Cdd:TIGR00871   1 DPCILVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEFRKVVREAIikFETDEIDE----QWDEFAQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  230 RTYYINGGYNNRDGMSRLAERMKQIEGE--SEANRIFYLSVPQEALVDVACTIGDNAQAPRG-WTRIIVEKPFGFNSHSS 306
Cdd:TIGR00871  77 RLSYVSGDVDDDESYDSLAELLEQLDKTygTEGNRLFYLATPPSLFGTIIKQLKKHGLNEQGkWSRVVVEKPFGHDLASA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  307 HQLTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAqTE---KFSDGYGIIRDI 383
Cdd:TIGR00871 157 QELNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQIFEPLWNRRYIDHVQITVAESFG-VEgrgGYYDKSGALRDM 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  384 VHSHILQTIALLAMEPPISLDGEDIRNEKVNlyckeqnrlmVLRSIRKIDPRD--VILGQYKSSS---------RDKNGV 452
Cdd:TIGR00871 236 VQNHLLQLLALVAMEPPVSFDADSIRDEKVK----------VLKALRPIDPDDnnTVRGQYGAGEiggvsvpgyLEEEGV 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  453 ILNGVDPTYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENigINIDLGTNELILRDEPDEAILV 532
Cdd:TIGR00871 306 DKDSNTETFAALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDVPSLLFKAN--ERDANPRNALVIRIQPDEGVYL 383

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  533 KINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTA-PELY 611
Cdd:TIGR00871 384 KFNAKKPGLNFETRPVKLDFSYASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTPILEAWAANKGPsPPNY 463

                         490       500
                  ....*....|....*....|.
gi 334182416  612 EFGGRGPVAAYYLWAKHGVPW 632
Cdd:TIGR00871 464 PAGSWGPKEADELIRKDGRSW 484
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 155-632 2.82e-153

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 451.07  E-value: 2.82e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 155 CIAVV-GATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLT--CRVDHQEncgGKMDAFQSRT 231
Cdd:COG0364   10 CDLVIfGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREALEefSRKPFDE---EVWERFLERL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 232 YYINGGYNNRDGMSRLAERMKQIEGE-SEANRIFYLSVPQEALVDVACTIGDNAQA-PRGWTRIIVEKPFGFNSHSSHQL 309
Cdd:COG0364   87 HYVSGDFTDPEGYERLKELLEELDEErTPGNRVFYLATPPSLFGPICENLGAAGLAtEGGWRRVVIEKPFGHDLASAREL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 310 TKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESI-----AqteKFSDGYGIIRDIV 384
Cdd:COG0364  167 NDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVgvegrG---GYYDGAGALRDMV 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 385 HSHILQTIALLAMEPPISLDGEDIRNEKVnlycKeqnrlmVLRSIRKIDPRDV----ILGQYKSssrdknGVIL------ 454
Cdd:COG0364  244 QNHLLQLLCLVAMEPPASLDADAIRDEKV----K------VLRALRPITPEDVaentVRGQYTA------GWIGgepvpg 307

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 455 ----NGVDP-----TYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENigiNIDLGTNELILRDE 525
Cdd:COG0364  308 yreePGVAPdstteTFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPVPHSLFRET---AEELPPNRLVIRIQ 384

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 526 PDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHH 605
Cdd:COG0364  385 PDEGISLRFNAKVPGLGMRLRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEP 464

                        490       500
                 ....*....|....*....|....*..
gi 334182416 606 TAPELYEFGGRGPVAAYYLWAKHGVPW 632
Cdd:COG0364  465 EPPPPYPAGSWGPEAADALLARDGRSW 491
G6PD_C pfam02781
Glucose-6-phosphate dehydrogenase, C-terminal domain;
339-632 3.24e-136

Glucose-6-phosphate dehydrogenase, C-terminal domain;


Pssm-ID: 460694  Cd Length: 295  Bit Score: 399.89  E-value: 3.24e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  339 VLRFSNLVFEPLWNRTYIRNIQVIISESIAqTEK---FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGEDIRNEKVNl 415
Cdd:pfam02781   2 VLRFANAIFEPLWNRNYIDHVQITVAETLG-VEGrggYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAEDIRDEKVK- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  416 yckeqnrlmVLRSIRKIDPRDV----ILGQYKSSSRDKNGVI----LNGVDP-----TYCAAALYIDNARWDGVPFLVRV 482
Cdd:pfam02781  80 ---------VLRSLRPITPEDVednvVRGQYGAGWIGGEPVPgyreEEGVPPdsrteTFAALKLFIDNWRWAGVPFYLRT 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  483 GTGLIKHRVEIHVQFRHVPGNLYRENIGinidLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEV 562
Cdd:pfam02781 151 GKRLPERVTEIRIQFKDVPHNLFRDPGT----LPPNELVIRIQPDEGIYLKFNAKVPGLGMRLRPVELDFSYSDRFGERI 226

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  563 PDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHtaPELYEFGGRGPVAAYYLWAKHGVPW 632
Cdd:pfam02781 227 PEAYERLLLDVMRGDQTLFVRSDEVEAAWRIVDPILEAWDEEK--PPPYPAGSWGPKAADELLARDGRKW 294
 
Name Accession Description Interval E-value
PLN02333 PLN02333
glucose-6-phosphate 1-dehydrogenase
 14-634 0e+00

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215191 [Multi-domain]  Cd Length: 604  Bit Score: 613.52  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  14 ATAPSSSVCSCHLAASFSNFPVSSrdysfSRSGSLVLNGggsnlcrrfcglklwilKSLNRRQGNNRKHQPVnELTTHSK 93
Cdd:PLN02333   2 ATLSSSHSCPYARSYSYSLSPSSS-----SSHSSVVDPH-----------------RSLSFLSAIPQGLNPA-KLCVRSQ 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  94 HTF-----LSDDERGFAEETRAEDLRPEENILGTDLNDGFHNVGDLPPVSKQLSDDLSDVRrraslcIAVVGATGELARG 168
Cdd:PLN02333  59 RNSyqnvvLMQDGAVATPSNPVENDSSFKKLKDGLLSSIPSSEEDKVVAEFDGNKDESTVS------ITVVGASGDLAKK 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 169 KIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENCGGKMDAFQSRTYYINGGYNNRDGMSRLA 248
Cdd:PLN02333 133 KIFPALFALYYEGCLPEHFTIFGYARSKMTDAELRNMVSKTLTCRIDKRENCGEKMEEFLKRCFYHSGQYDSQEHFAELD 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 249 ERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQLTKSLLSKFEEKQIYRIDHM 328
Cdd:PLN02333 213 KKLKEHEGGRVSNRLFYLSIPPNIFVDAVKCASSSASSVNGWTRVIVEKPFGRDSESSAALTKSLKQYLEEDQIFRIDHY 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 329 LGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAQTEK--FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGE 406
Cdd:PLN02333 293 LGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRggYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAE 372

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 407 DIRNEKVNlyckeqnrlmVLRSIRKIDPRDVILGQYKSSSR---------DKNGVILNGVDPTYCAAALYIDNARWDGVP 477
Cdd:PLN02333 373 DIRNEKVK----------VLRSMRPIQLEDVVIGQYKSHTKggvtypaytDDKTVPKGSLTPTFAAAALFIDNARWDGVP 442

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 478 FLVRVGTGLIKHRVEIHVQFRHVPGNLYRENIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDR 557
Cdd:PLN02333 443 FLMKAGKALHTKSAEIRVQFRHVPGNLYNRNFGTDLDQATNELVIRVQPDEAIYLKINNKVPGLGMRLDRSNLNLLYAAR 522

                        570       580       590       600       610       620       630
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334182416 558 YKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHGVPWAD 634
Cdd:PLN02333 523 YSKEIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPVGAHYLAARYKVRWGD 599
PLN02640 PLN02640
glucose-6-phosphate 1-dehydrogenase
 152-634 0e+00

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215344 [Multi-domain]  Cd Length: 573  Bit Score: 610.09  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 152 ASLCIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENCGGKMDAFQSRT 231
Cdd:PLN02640  87 STLSITVVGASGDLAKKKIFPALFALFYEDWLPENFTVFGYARTKLTDEELRDMISSTLTCRIDQRENCGDKMDQFLKRC 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 232 YYINGGYNNRDGMSRLAERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQLTK 311
Cdd:PLN02640 167 FYHSGQYDSEEDFAELNKKLKEKEAGKLSNRLFYLSIPPNIFVDVVRCASLRASSENGWTRVIVEKPFGRDSESSGELTR 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 312 SLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAQTEK--FSDGYGIIRDIVHSHIL 389
Cdd:PLN02640 247 CLKQYLTEEQIFRIDHYLGKELVENLSVLRFSNLVFEPLWSRNYIRNVQLIFSEDFGTEGRggYFDNYGIIRDIMQNHLL 326

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 390 QTIALLAMEPPISLDGEDIRNEKVNlyckeqnrlmVLRSIRKIDPRDVILGQYKSSSR---------DKNGVILNGVDPT 460
Cdd:PLN02640 327 QILALFAMETPVSLDAEDIRNEKVK----------VLRSMKPLQLEDVIVGQYKGHSKggksypaytDDPTVPKHSLTPT 396

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 461 YCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENIGINIDLGTNELILRDEPDEAILVKINNKVPG 540
Cdd:PLN02640 397 FAAAALFINNARWDGVPFLMKAGKALHTRRAEIRVQFRHVPGNLYKRNFGTDLDKATNELVLRVQPDEAIYLKINNKVPG 476

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 541 LGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVA 620
Cdd:PLN02640 477 LGMRLDRSDLNLLYRARYPREIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPELYPYGSRGPVG 556

                        490
                 ....*....|....
gi 334182416 621 AYYLWAKHGVPWAD 634
Cdd:PLN02640 557 AHYLAAKYNVRWGD 570
PTZ00309 PTZ00309
glucose-6-phosphate 1-dehydrogenase; Provisional
 130-629 4.01e-160

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 240353 [Multi-domain]  Cd Length: 542  Bit Score: 470.39  E-value: 4.01e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 130 NVGDLPPVSKQLSDDLSDVRRRASLCIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDlRSIIAST 209
Cdd:PTZ00309  31 KPDNGTESCDRIPCKVKDEDKSRALTIIVLGASGDLAKKKTFPALFQLYCEGLLPSEVNIVGYARSKMSDVE-RWKKETL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 210 LTCRVDHQENCGgKMDAFQSRTYYINGGYNNRDGMSRLAERMKQIEG-----ESEANRIFYLSVPQEALVDVACTIGDNA 284
Cdd:PTZ00309 110 ARFFKRLDDREC-HLEQFLKHISYISGSYDEDEDFKRLNKLIERMEEafqgpEKGGNRLFYLALPPSVFASVCEGIHRGC 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 285 QAPRGWTRIIVEKPFGFNSHSSHQLTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIIS 364
Cdd:PTZ00309 189 MSKNGWVRVIVEKPFGRDLESSEELSNQLEPLFDESQLYRIDHYLGKEMVQNLIVLRFANRVFEPLWNRNNIACVQITFK 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 365 ESIAqTE---KFSDGYGIIRDIVHSHILQTIALLAMEPPISLDGEDIRNEKVNlyckeqnrlmVLRSIRKIDPRDVILGQ 441
Cdd:PTZ00309 269 EDIG-TEgrgGYFDSYGIIRDVMQNHLLQILALLAMEKPVSLSAEDIRDEKVK----------VLKCIEPIKMEECVLGQ 337

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 442 YKSSS-------RDKNGVILNGVDPTYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYrenigINID 514
Cdd:PTZ00309 338 YTASAdgsipgyLEDEGVPKDSTTPTFAAAVLHINNDRWEGVPFILEAGKALEERYVEIRIQFKGVDEFRP-----SGDD 412

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 515 LGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNIL 594
Cdd:PTZ00309 413 TQRNELVIRAQPSEAMYLKITAKVPGLSNDLHQTELDLTYKTRYNVRLPDAYERLILDALLGDSTNFVRKDELDVAWRIF 492

                        490       500       510
                 ....*....|....*....|....*....|....*
gi 334182416 595 SPVLEEIDKHHTAPELYEFGGRGPVAAYYLWAKHG 629
Cdd:PTZ00309 493 TPLLHQIDRGEVKPEPYPFGSRGPKEADELIKKNG 527
zwf TIGR00871
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ...
 152-632 3.43e-156

glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273312 [Multi-domain]  Cd Length: 487  Bit Score: 458.32  E-value: 3.43e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  152 ASLCIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTL--TCRVDHQEncggKMDAFQS 229
Cdd:TIGR00871   1 DPCILVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEFRKVVREAIikFETDEIDE----QWDEFAQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  230 RTYYINGGYNNRDGMSRLAERMKQIEGE--SEANRIFYLSVPQEALVDVACTIGDNAQAPRG-WTRIIVEKPFGFNSHSS 306
Cdd:TIGR00871  77 RLSYVSGDVDDDESYDSLAELLEQLDKTygTEGNRLFYLATPPSLFGTIIKQLKKHGLNEQGkWSRVVVEKPFGHDLASA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  307 HQLTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAqTE---KFSDGYGIIRDI 383
Cdd:TIGR00871 157 QELNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQIFEPLWNRRYIDHVQITVAESFG-VEgrgGYYDKSGALRDM 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  384 VHSHILQTIALLAMEPPISLDGEDIRNEKVNlyckeqnrlmVLRSIRKIDPRD--VILGQYKSSS---------RDKNGV 452
Cdd:TIGR00871 236 VQNHLLQLLALVAMEPPVSFDADSIRDEKVK----------VLKALRPIDPDDnnTVRGQYGAGEiggvsvpgyLEEEGV 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  453 ILNGVDPTYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENigINIDLGTNELILRDEPDEAILV 532
Cdd:TIGR00871 306 DKDSNTETFAALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDVPSLLFKAN--ERDANPRNALVIRIQPDEGVYL 383

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  533 KINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTA-PELY 611
Cdd:TIGR00871 384 KFNAKKPGLNFETRPVKLDFSYASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTPILEAWAANKGPsPPNY 463

                         490       500
                  ....*....|....*....|.
gi 334182416  612 EFGGRGPVAAYYLWAKHGVPW 632
Cdd:TIGR00871 464 PAGSWGPKEADELIRKDGRSW 484
PRK05722 PRK05722
glucose-6-phosphate 1-dehydrogenase; Validated
 155-632 2.20e-154

glucose-6-phosphate 1-dehydrogenase; Validated


Pssm-ID: 235579 [Multi-domain]  Cd Length: 495  Bit Score: 453.82  E-value: 2.20e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 155 CIAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVdHQENCGGKMDAFQSRTYYI 234
Cdd:PRK05722  11 DLVIFGATGDLARRKLLPALYNLYKAGLLPEDFRIIGVARRDWSDEDFREVVREALKEFA-RTPFDEEVWERFLSRLYYV 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 235 NGGYNNRDGMSRLAERMKQIEGESEA--NRIFYLSVPQEALVDVACTIGDNAQA-PRGWTRIIVEKPFGFNSHSSHQLTK 311
Cdd:PRK05722  90 SGDVTDPESYERLKELLEELDEERGTggNRVFYLATPPSLFGTICENLAAAGLNeGGGWRRVVIEKPFGHDLASARELND 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 312 SLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAqTEK---FSDGYGIIRDIVHSHI 388
Cdd:PRK05722 170 QVGEVFKEEQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVG-VEGrggYYDKSGALRDMVQNHL 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 389 LQTIALLAMEPPISLDGEDIRNEKVNlyckeqnrlmVLRSIRKIDPRDV----ILGQYKSSS---------RDKNGVILN 455
Cdd:PRK05722 249 LQLLALVAMEPPASLDADSIRDEKVK----------VLRALRPITPEDVkentVRGQYTAGWiggkpvpgyREEEGVNPD 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 456 GVDPTYCAAALYIDNARWDGVPFLVRVGTGLiKHRV-EIHVQFRHVPGNLYRENIGiniDLGTNELILRDEPDEAILVKI 534
Cdd:PRK05722 319 STTETFVALKLEIDNWRWAGVPFYLRTGKRL-PKKVtEIVIVFKPPPHNLFEESAE---ELGPNKLVIRIQPDEGISLRF 394

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 535 NNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFG 614
Cdd:PRK05722 395 NAKVPGEGMELRPVKLDFSYSEAFGEASPEAYERLLLDVMLGDQTLFVRRDEVEAAWKWVDPILEAWEADGGPPPPYPAG 474

                        490
                 ....*....|....*...
gi 334182416 615 GRGPVAAYYLWAKHGVPW 632
Cdd:PRK05722 475 TWGPEAADALLARDGRSW 492
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 155-632 2.82e-153

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 451.07  E-value: 2.82e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 155 CIAVV-GATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLT--CRVDHQEncgGKMDAFQSRT 231
Cdd:COG0364   10 CDLVIfGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSDEEFREEVREALEefSRKPFDE---EVWERFLERL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 232 YYINGGYNNRDGMSRLAERMKQIEGE-SEANRIFYLSVPQEALVDVACTIGDNAQA-PRGWTRIIVEKPFGFNSHSSHQL 309
Cdd:COG0364   87 HYVSGDFTDPEGYERLKELLEELDEErTPGNRVFYLATPPSLFGPICENLGAAGLAtEGGWRRVVIEKPFGHDLASAREL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 310 TKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESI-----AqteKFSDGYGIIRDIV 384
Cdd:COG0364  167 NDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVgvegrG---GYYDGAGALRDMV 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 385 HSHILQTIALLAMEPPISLDGEDIRNEKVnlycKeqnrlmVLRSIRKIDPRDV----ILGQYKSssrdknGVIL------ 454
Cdd:COG0364  244 QNHLLQLLCLVAMEPPASLDADAIRDEKV----K------VLRALRPITPEDVaentVRGQYTA------GWIGgepvpg 307

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 455 ----NGVDP-----TYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENigiNIDLGTNELILRDE 525
Cdd:COG0364  308 yreePGVAPdstteTFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPVPHSLFRET---AEELPPNRLVIRIQ 384

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 526 PDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHH 605
Cdd:COG0364  385 PDEGISLRFNAKVPGLGMRLRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEP 464

                        490       500
                 ....*....|....*....|....*..
gi 334182416 606 TAPELYEFGGRGPVAAYYLWAKHGVPW 632
Cdd:COG0364  465 EPPPPYPAGSWGPEAADALLARDGRSW 491
PLN02539 PLN02539
glucose-6-phosphate 1-dehydrogenase
 154-629 2.49e-142

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 178154 [Multi-domain]  Cd Length: 491  Bit Score: 422.98  E-value: 2.49e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 154 LCIAVVGATGELARGKIFPALFALYYSGYLPED-VAIFGVSRKNLTDEDLRSIIASTLtcrVDHQENCGGKMDAFQSRTY 232
Cdd:PLN02539  18 LSIIVLGASGDLAKKKTFPALFNLYRQGFLPPDeVHIFGYARSKITDEELRDRIRGYL---KDEKNAPAEAVSKFLQLIK 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 233 YINGGYNNRDGMSRLAERMKQIE-----GESEANRIFYLSVPQEALVDVACTIGDNAQAPRG-WTRIIVEKPFGFNSHSS 306
Cdd:PLN02539  95 YVSGAYDSEEGFRRLDKEISEHEisknsAEGSSRRLFYLALPPSVYPPVCKMIKKCCMNKSGlWTRIVVEKPFGKDLESA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 307 HQLTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIAqTE---KFSDGYGIIRDI 383
Cdd:PLN02539 175 EELSSQIGELFDESQLYRIDHYLGKELVQNLLVLRFANRFFLPLWNRDNIANVQIVFREDFG-TEgrgGYFDEYGIIRDI 253

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 384 VHSHILQTIALLAMEPPISLDGEDIRNEKVNlyckeqnrlmVLRSIRKIDPRDVILGQYKsSSRDKNGVILNGVDPTYCA 463
Cdd:PLN02539 254 IQNHLLQVLCLVAMEKPVSLKPEHIRDEKVK----------VLQSVEPIKDEEVVLGQYE-GYRDDPTVPDDSNTPTFAS 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 464 AALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRENiginiDLGTNELILRDEPDEAILVKINNKVPGLGL 543
Cdd:PLN02539 323 VVLRINNERWEGVPFILKAGKALDSRKAEIRVQFKDVPGDIFKCQ-----KQGRNEFVIRLQPSEAMYMKLTVKQPGLEM 397

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 544 QLDASELNLLYKDRYK-TEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGGRGPVAAY 622
Cdd:PLN02539 398 STVQSELDLSYGQRYQdVVIPEAYERLILDTIRGDQQHFVRRDELKAAWEIFTPLLHRIDAGKVKPIPYKQGSRGPAEAD 477


                 ....*..
gi 334182416 623 YLWAKHG 629
Cdd:PLN02539 478 ELLEKAG 484
G6PD_C pfam02781
Glucose-6-phosphate dehydrogenase, C-terminal domain;
339-632 3.24e-136

Glucose-6-phosphate dehydrogenase, C-terminal domain;


Pssm-ID: 460694  Cd Length: 295  Bit Score: 399.89  E-value: 3.24e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  339 VLRFSNLVFEPLWNRTYIRNIQVIISESIAqTEK---FSDGYGIIRDIVHSHILQTIALLAMEPPISLDGEDIRNEKVNl 415
Cdd:pfam02781   2 VLRFANAIFEPLWNRNYIDHVQITVAETLG-VEGrggYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAEDIRDEKVK- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  416 yckeqnrlmVLRSIRKIDPRDV----ILGQYKSSSRDKNGVI----LNGVDP-----TYCAAALYIDNARWDGVPFLVRV 482
Cdd:pfam02781  80 ---------VLRSLRPITPEDVednvVRGQYGAGWIGGEPVPgyreEEGVPPdsrteTFAALKLFIDNWRWAGVPFYLRT 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  483 GTGLIKHRVEIHVQFRHVPGNLYRENIGinidLGTNELILRDEPDEAILVKINNKVPGLGLQLDASELNLLYKDRYKTEV 562
Cdd:pfam02781 151 GKRLPERVTEIRIQFKDVPHNLFRDPGT----LPPNELVIRIQPDEGIYLKFNAKVPGLGMRLRPVELDFSYSDRFGERI 226

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  563 PDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHtaPELYEFGGRGPVAAYYLWAKHGVPW 632
Cdd:pfam02781 227 PEAYERLLLDVMRGDQTLFVRSDEVEAAWRIVDPILEAWDEEK--PPPYPAGSWGPKAADELLARDGRKW 294
PRK12853 PRK12853
glucose-6-phosphate dehydrogenase;
155-632 2.63e-132

glucose-6-phosphate dehydrogenase;


Pssm-ID: 237233 [Multi-domain]  Cd Length: 482  Bit Score: 396.96  E-value: 2.63e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 155 CIAVV-GATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLtcrvdhQENCGGKMDA-----FQ 228
Cdd:PRK12853   9 CTLVIfGATGDLARRKLLPALYRLARAGLLPEDLRIIGVGRDDWSDEQWRARVRESL------RAFGADGFDDavwdrLA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 229 SRTYYINGGYNNRDGMSRLAERMkqiegESEANRIFYLSVPQEALVDVaCTIGDNAQAPRGWTRIIVEKPFGFNSHSSHQ 308
Cdd:PRK12853  83 ARLSYVQGDVTDPADYARLAEAL-----GPGGNPVFYLAVPPSLFAPV-VENLGAAGLLPEGRRVVLEKPFGHDLASARA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 309 LTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISESIA--QTEKFSDGYGIIRDIVHS 386
Cdd:PRK12853 157 LNATLAKVFDEDQIYRIDHFLGKETVQNLLALRFANALLEPLWNRNHIDHVQITVAETLGveGRGGFYDATGALRDMVQN 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 387 HILQTIALLAMEPPISLDGEDIRNEKVNlyckeqnrlmVLRSIRKIDPRDVIL--GQYKSSSRDKNGVI----LNGVDP- 459
Cdd:PRK12853 237 HLLQLLALVAMEPPASFDADAVRDEKAK----------VLRAIRPLDPDDVHTvrGQYTAGTVGGEPVPgyreEPGVDPd 306

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 460 ----TYCAAALYIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYREnigiNIDLGTNELILRDEPDEAILVKIN 535
Cdd:PRK12853 307 srteTFVALKLEIDNWRWAGVPFYLRTGKRLAERRTEIVITFKPVPHALFRG----TGVEPPNRLVIRLQPDEGISLELN 382

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 536 NKVPGLGLQLDASELNLLYKDRykTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEEIDKHHTAPELYEFGG 615
Cdd:PRK12853 383 VKRPGPGMRLRPVELDADYADD--ERPLEAYERLLLDVLRGDPTLFVRADEVEAAWRIVDPVLDAWAADPVPPHEYPAGS 460

                        490
                 ....*....|....*..
gi 334182416 616 RGPVAAYYLWAKHGVPW 632
Cdd:PRK12853 461 WGPAAADALLARDGRGW 477
PRK12854 PRK12854
glucose-6-phosphate 1-dehydrogenase; Provisional
 156-629 8.42e-108

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 237234 [Multi-domain]  Cd Length: 484  Bit Score: 333.93  E-value: 8.42e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 156 IAVVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIastltcRVDHQENCGGKMD-----AFQSR 230
Cdd:PRK12854  14 FVLFGATGDLAKRKLLPGLFHLARAGLLPPDWRIVGTGRGDVSAEAFREHA------RDALDEFGARKLDdgewaRFAKR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 231 TYYINGGYNNrDGMSRLAERMKQIEGE--SEANRIFYLSVPQEALVDVACTIGDNAQAPRgwTRIIVEKPFGFNSHSSHQ 308
Cdd:PRK12854  88 LRYVPGGFLS-AGPGALAAAVAAARAElgGDARLVHYLAVPPSAFLDVTRALGEAGLAEG--SRVVMEKPFGTDLASAEA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 309 LTKSLLSKFEEKQIYRIDHMLGRNLIENLTVLRFSNLVFEPLWNRTYIRNIQVIISES--IAQTEKFSDGYGIIRDIVHS 386
Cdd:PRK12854 165 LNAAVHEVFDESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNREFIDHVQIDVPETlgVDTRAAFYDATGAYRDMVVT 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 387 HILQTIALLAMEPPISLDGEDIRNEKvnlyckeqnrLMVLRSIRKIDPRDVILGQYkSSSRDKNGVILNGVDPTYCAAAL 466
Cdd:PRK12854 245 HLFQVLAFVAMEPPTALEPDAISEEK----------NKVFRSMRPLDPAEVVRGQY-SGYRDEPGVAPDSTTETFVALKV 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 467 YIDNARWDGVPFLVRVGTGLIKHRVEIHVQFRHVPGNLYRenIGINIDLGTNELILRDEPDEAILVKINNKVPGLGLQLD 546
Cdd:PRK12854 314 WIDNWRWAGVPFYLRTGKRMAEGQRIISIAFREPPYSMFP--AGSVGAQGPDHLTFDLADNSKVSLSFYGKRPGPGMRLD 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416 547 ASELNLLYKD-RYKTEVPDSYEHLIHDVIDGDNHLFMRSDEVAAAWNILSPVLEeidkHHTAPELYEFGGRGPVAAYYLW 625
Cdd:PRK12854 392 KLSLQFSLKDtGPKGDVLEAYERLILDALRGDHTLFTTADGIESLWEVSQPLLE----DPPPVKPYAPGSWGPNAIHQLA 467


                 ....
gi 334182416 626 AKHG 629
Cdd:PRK12854 468 APDA 471
G6PD_N pfam00479
Glucose-6-phosphate dehydrogenase, NAD binding domain;
158-336 2.32e-58

Glucose-6-phosphate dehydrogenase, NAD binding domain;


Pssm-ID: 459827 [Multi-domain]  Cd Length: 178  Bit Score: 193.79  E-value: 2.32e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  158 VVGATGELARGKIFPALFALYYSGYLPEDVAIFGVSRKNLTDEDLRSIIASTLTCRVDHQENcggKMDAFQSRTYYINGG 237
Cdd:pfam00479   2 IFGATGDLAKRKLFPALYNLYRDGLLPEGFRIIGVARRDLSDEEFRERVREALKEFKELDEE---KWDRFLERLHYVSGD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334182416  238 YNNRDGMSRLAERMKQIEGESEANRIFYLSVPQEALVDVACTIGDNAQAPR-GWTRIIVEKPFGFNSHSSHQLTKSLLSK 316
Cdd:pfam00479  79 FDDPESYEKLKERLEEHEDETRGNRLFYLAVPPSLFGPIAENLGRAGLSEEgGWRRVVIEKPFGHDLESARELNDQLAKV 158

                         170       180
                  ....*....|....*....|
gi 334182416  317 FEEKQIYRIDHMLGRNLIEN 336
Cdd:pfam00479 159 FKEEQIYRIDHYLGKETVQN 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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