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Conserved domains on  [gi|300793996|ref|NP_001178595|]
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trichoplein keratin filament-binding protein [Rattus norvegicus]

Protein Classification

trichohyalin-plectin-homology domain domain-containing protein( domain architecture ID 12159040)

trichohyalin-plectin-homology domain (TPH) domain-containing protein similar to meiosis-specific nuclear structural protein 1, trichoplein keratin filament-binding protein, and cilia- and flagella-associated proteins

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 142-481 9.29e-20

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


:

Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 90.36  E-value: 9.29e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  142 WRKNNPKLREIELDLHKKHVINSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQGEALRQ 221
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  222 QMEELKQKEMEATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADGRILQA 301
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  302 LLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAE---LQQLLREEAKEMWEKREAEWAREQSARDKLMSEv 378
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERdelRAKLYQEEQERKERQKEREEAEKKARQRQELQQ- 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  379 ltGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELEAQVAERQFQEWEAARQEEEEE 458
Cdd:pfam13868 240 --AREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEG 317

                         330       340
                  ....*....|....*....|...
gi 300793996  459 KEAKKAEQLSNARLQQEARTMVK 481
Cdd:pfam13868 318 ERLREEEAERRERIEEERQKKLK 340
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 142-481 9.29e-20

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 90.36  E-value: 9.29e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  142 WRKNNPKLREIELDLHKKHVINSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQGEALRQ 221
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  222 QMEELKQKEMEATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADGRILQA 301
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  302 LLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAE---LQQLLREEAKEMWEKREAEWAREQSARDKLMSEv 378
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERdelRAKLYQEEQERKERQKEREEAEKKARQRQELQQ- 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  379 ltGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELEAQVAERQFQEWEAARQEEEEE 458
Cdd:pfam13868 240 --AREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEG 317

                         330       340
                  ....*....|....*....|...
gi 300793996  459 KEAKKAEQLSNARLQQEARTMVK 481
Cdd:pfam13868 318 ERLREEEAERRERIEEERQKKLK 340
PTZ00121 PTZ00121
MAEBL; Provisional
 49-482 3.64e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 3.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   49 KQTEWTSKTSYQRSMHALYCGKMEEERRKNLEVRRERLRKLMLEEQDLLAEELEELRLSMSLRE-RRLREQHRDLKSARE 127
Cdd:PTZ00121 1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKAD 1408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  128 EQRKLMAEQLLYEHWRKNNPKLREIElDLHKKhvinSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEER 207
Cdd:PTZ00121 1409 ELKKAAAAKKKADEAKKKAEEKKKAD-EAKKK----AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  208 KQLEGQLQGEALRQQMEELKQKEME---ATKLKKEQENllKQHWELERLDDERK----QMAIVRRKTELGRILRHQYNAQ 280
Cdd:PTZ00121 1484 KADEAKKKAEEAKKKADEAKKAAEAkkkADEAKKAEEA--KKADEAKKAEEAKKadeaKKAEEKKKADELKKAEELKKAE 1561

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  281 LNRRTQQIQEELEADGRILQalleKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREE-------- 352
Cdd:PTZ00121 1562 EKKKAEEAKKAEEDKNMALR----KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEeekkkveq 1637

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  353 --AKEMWEKREAEWAREQSARDKLMSEVLTGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKS 430
Cdd:PTZ00121 1638 lkKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 300793996  431 ARKQELEAQVAERQFQEWEAARQEEEEEKEAKKAEQLSNARLQQEARTMVKR 482
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 201-495 5.72e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 5.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 201 LKAEEERKQLEGQLQGEALRQQMEELKQKEMEATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRhQYNAQ 280
Cdd:COG1196  218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY-ELLAE 296

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 281 LNRRTQQIQEELEADGRILQALLEKDNELQQVE--LARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMWE 358
Cdd:COG1196  297 LARLEQDIARLEERRRELEERLEELEEELAELEeeLEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 359 KREAEWAREQSARDKLMSE-VLTGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELE 437
Cdd:COG1196  377 AEEELEELAEELLEALRAAaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 300793996 438 AQVAERQFQEWEAARQEEEEEKEAKKAEQLSNARLQQEARTMVKRGYRPKIHGHLRIA 495
Cdd:COG1196  457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 202-446 4.19e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 4.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   202 KAEEERKQLEGQLQG--EALRQQMEELKQKEMEATKLKKEQENLLKQHWELERlddeRKQMAIVRRKTELGRILRHQYNA 279
Cdd:TIGR02168  250 EAEEELEELTAELQEleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ----QKQILRERLANLERQLEELEAQL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   280 QLNRRTQQIQEELEADGRILQALLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMwEK 359
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-ER 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   360 REAEWAREQSARDKLMSEVLTGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARkQELEAQ 439
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL-DAAERE 483


                   ....*..
gi 300793996   440 VAERQFQ 446
Cdd:TIGR02168  484 LAQLQAR 490
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 142-481 9.29e-20

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 90.36  E-value: 9.29e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  142 WRKNNPKLREIELDLHKKHVINSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQGEALRQ 221
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  222 QMEELKQKEMEATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADGRILQA 301
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  302 LLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAE---LQQLLREEAKEMWEKREAEWAREQSARDKLMSEv 378
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERdelRAKLYQEEQERKERQKEREEAEKKARQRQELQQ- 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  379 ltGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELEAQVAERQFQEWEAARQEEEEE 458
Cdd:pfam13868 240 --AREEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEG 317

                         330       340
                  ....*....|....*....|...
gi 300793996  459 KEAKKAEQLSNARLQQEARTMVK 481
Cdd:pfam13868 318 ERLREEEAERRERIEEERQKKLK 340
PTZ00121 PTZ00121
MAEBL; Provisional
 49-482 3.64e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.93  E-value: 3.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   49 KQTEWTSKTSYQRSMHALYCGKMEEERRKNLEVRRERLRKLMLEEQDLLAEELEELRLSMSLRE-RRLREQHRDLKSARE 127
Cdd:PTZ00121 1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKaDEAKKKAEEDKKKAD 1408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  128 EQRKLMAEQLLYEHWRKNNPKLREIElDLHKKhvinSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEER 207
Cdd:PTZ00121 1409 ELKKAAAAKKKADEAKKKAEEKKKAD-EAKKK----AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  208 KQLEGQLQGEALRQQMEELKQKEME---ATKLKKEQENllKQHWELERLDDERK----QMAIVRRKTELGRILRHQYNAQ 280
Cdd:PTZ00121 1484 KADEAKKKAEEAKKKADEAKKAAEAkkkADEAKKAEEA--KKADEAKKAEEAKKadeaKKAEEKKKADELKKAEELKKAE 1561

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  281 LNRRTQQIQEELEADGRILQalleKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREE-------- 352
Cdd:PTZ00121 1562 EKKKAEEAKKAEEDKNMALR----KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEeekkkveq 1637

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  353 --AKEMWEKREAEWAREQSARDKLMSEVLTGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKS 430
Cdd:PTZ00121 1638 lkKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 300793996  431 ARKQELEAQVAERQFQEWEAARQEEEEEKEAKKAEQLSNARLQQEARTMVKR 482
Cdd:PTZ00121 1718 AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKK 1769
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 201-495 5.72e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 5.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 201 LKAEEERKQLEGQLQGEALRQQMEELKQKEMEATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRhQYNAQ 280
Cdd:COG1196  218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEY-ELLAE 296

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 281 LNRRTQQIQEELEADGRILQALLEKDNELQQVE--LARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMWE 358
Cdd:COG1196  297 LARLEQDIARLEERRRELEERLEELEEELAELEeeLEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 359 KREAEWAREQSARDKLMSE-VLTGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELE 437
Cdd:COG1196  377 AEEELEELAEELLEALRAAaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 300793996 438 AQVAERQFQEWEAARQEEEEEKEAKKAEQLSNARLQQEARTMVKRGYRPKIHGHLRIA 495
Cdd:COG1196  457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 148-444 1.93e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.42  E-value: 1.93e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 148 KLREIELDLHKKHVINSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQGEALRQQMEELK 227
Cdd:COG1196  223 KELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ 302

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 228 QKEMEATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADGRILQALLEKDN 307
Cdd:COG1196  303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 308 ELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMWEKREAEWAREQSARDKLMSEVLTGRQQQIQ 387
Cdd:COG1196  383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 300793996 388 EKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELEAQVAERQ 444
Cdd:COG1196  463 ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
PTZ00121 PTZ00121
MAEBL; Provisional
 70-487 1.74e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 1.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   70 KMEEERRKNLEVRRERLRKLMLEEQDLLAEELEELRLSMSLRERRlREQHRDLKSAREEQRKLMAEQLLYEHWRKNNPKL 149
Cdd:PTZ00121 1372 KKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA-KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK 1450

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  150 REIEldlHKKHVINSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEArlKAEEERKQLEGQLQGEALRQQMEELKQK 229
Cdd:PTZ00121 1451 KKAE---EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKK--KADEAKKAAEAKKKADEAKKAEEAKKAD 1525

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  230 EMEATKLKKEQENLLKQHwELERLDDERK----QMAIVRRKTELGRILRHQYNAQLnRRTQQIQEELEADGRILQALLEK 305
Cdd:PTZ00121 1526 EAKKAEEAKKADEAKKAE-EKKKADELKKaeelKKAEEKKKAEEAKKAEEDKNMAL-RKAEEAKKAEEARIEEVMKLYEE 1603

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  306 DNELQQVELARREQAMADAAQMKQVIEEQ---LQLEKAREAELQQLLREEAKEMWEKREAEWAREQSARDKLMSEVLTGR 382
Cdd:PTZ00121 1604 EKKMKAEEAKKAEEAKIKAEELKKAEEEKkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA 1683

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  383 QQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELEAQVAERQFQEWEAARQEEEEEKEAK 462
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLK 1763

                         410       420
                  ....*....|....*....|....*
gi 300793996  463 KAEQLSNARLQQEARTMVKRGYRPK 487
Cdd:PTZ00121 1764 KEEEKKAEEIRKEKEAVIEEELDEE 1788
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 220-477 5.32e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 220 RQQMEELKQKEMEATKLKKEQENLlkqhwELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADGRIL 299
Cdd:COG1196  216 RELKEELKELEAELLLLKLRELEA-----ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 300 QALLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMWEKREAEWAREQSARDKLMSEVL 379
Cdd:COG1196  291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 380 TGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELEAQVAERQFQEWEAARQEEEEEK 459
Cdd:COG1196  371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                        250
                 ....*....|....*...
gi 300793996 460 EAKKAEQLSNARLQQEAR 477
Cdd:COG1196  451 EAELEEEEEALLELLAEL 468
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 110-432 6.00e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 6.00e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 110 LRERRLREQHRDLKSAREEQRKLMAEQLLYEhwrknnpklREIELDLHKKHVINSWATQKEEKKQQEATEKQENKQFENE 189
Cdd:COG1196  222 LKELEAELLLLKLRELEAELEELEAELEELE---------AELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 190 YAAARQEAEARLKAEEERKQLEGQLQGEALRQQMEELKQKEMEATKLKKEQEnllkqhwELERLDDERKQMAIVRRKTEL 269
Cdd:COG1196  293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE-------ELEEAEEELEEAEAELAEAEE 365

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 270 griLRHQYNAQLNRRTQQIQEELEADGRILQALLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLL 349
Cdd:COG1196  366 ---ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 350 REEakemwEKREAEWAREQSARDKLMSEVLTGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELK 429
Cdd:COG1196  443 ALE-----EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLA 517


                 ...
gi 300793996 430 SAR 432
Cdd:COG1196  518 GLR 520
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 72-482 7.68e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 7.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  72 EEERRKNLEVRRERLRKlmleeqdllaeELEELRLSMSLRERRLREQHRDLKSAREEQRKLMAEQLlyehwrknnpKLRE 151
Cdd:COG1196  307 LEERRRELEERLEELEE-----------ELAELEEELEELEEELEELEEELEEAEEELEEAEAELA----------EAEE 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 152 IELDLHKKhvINSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQGEALRQQMEELKQKEM 231
Cdd:COG1196  366 ALLEAEAE--LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 232 EATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADGRILQALLEKDNELQQ 311
Cdd:COG1196  444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 312 VELA--------------------RREQAMADAAQMKQVIEEQ----------LQLEKAREAELQQLLREEAKEMWEKRE 361
Cdd:COG1196  524 GAVAvligveaayeaaleaalaaaLQNIVVEDDEVAAAAIEYLkaakagratfLPLDKIRARAALAAALARGAIGAAVDL 603

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 362 -AEWAREQSARDKLMSEVLTGRQQQIQEKIEQNRRAQEETLKYREELI--KSLEEGKQLALRAKEESEELKSARKQELEA 438
Cdd:COG1196  604 vASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLegEGGSAGGSLTGGSRRELLAALLEAEAELEE 683

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....
gi 300793996 439 QVAERQFQEWEAARQEEEEEKEAKKAEQLSNARLQQEARTMVKR 482
Cdd:COG1196  684 LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALE 727
PTZ00121 PTZ00121
MAEBL; Provisional
 143-431 2.76e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 2.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  143 RKNNPKLREIELDLHKKHVINSwaTQKEEKKQQEATEKQENKQFENEyaaarQEAEARLKAEEERKQLEGQLQGEALRQQ 222
Cdd:PTZ00121 1070 EGLKPSYKDFDFDAKEDNRADE--ATEEAFGKAEEAKKTETGKAEEA-----RKAEEAKKKAEDARKAEEARKAEDARKA 1142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  223 MEELKQKEMEATKLKKEQENLLKQhwELERLDDERKQMAIVRRKTELGRI--LRHQYNAQLNRRTQQIQEELEADgrilq 300
Cdd:PTZ00121 1143 EEARKAEDAKRVEIARKAEDARKA--EEARKAEDAKKAEAARKAEEVRKAeeLRKAEDARKAEAARKAEEERKAE----- 1215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  301 allekdnELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMWEKREAEWAREQSARDKLMSEVLT 380
Cdd:PTZ00121 1216 -------EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 300793996  381 GRQQQIQEKIEQNRRAQE-----ETLKYREELIKSLEEGKQLALRAKEESEELKSA 431
Cdd:PTZ00121 1289 KKKADEAKKAEEKKKADEakkkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKA 1344
PTZ00121 PTZ00121
MAEBL; Provisional
 70-366 3.51e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 3.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   70 KMEEERRKNLEVRRERLRKLMLEEQDLLAEELEELRLSMSLRE----RRLREQHRDLKSAREEQRKLMAEQLLYEHWRKN 145
Cdd:PTZ00121 1511 KADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKaeelKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  146 NPKLREIELDLHKKHVINSWATQKEEKKQQEATE-KQENKQFENEYAAARQEAEARLKAEEERKQLE-GQLQGEALRQQM 223
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEeNKIKAAEEAKKA 1670

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  224 EELKQKemeATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTElgrilrhqynAQLNRRTQQIQEELEADGRILQALL 303
Cdd:PTZ00121 1671 EEDKKK---AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA----------EEKKKAEELKKAEEENKIKAEEAKK 1737

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 300793996  304 EKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAElqQLLREEAKEMWEKREAEWAR 366
Cdd:PTZ00121 1738 EAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE--AVIEEELDEEDEKRRMEVDK 1798
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 202-446 4.19e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 4.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   202 KAEEERKQLEGQLQG--EALRQQMEELKQKEMEATKLKKEQENLLKQHWELERlddeRKQMAIVRRKTELGRILRHQYNA 279
Cdd:TIGR02168  250 EAEEELEELTAELQEleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ----QKQILRERLANLERQLEELEAQL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   280 QLNRRTQQIQEELEADGRILQALLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMwEK 359
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-ER 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   360 REAEWAREQSARDKLMSEVLTGRQQQIQEKIEQNRRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARkQELEAQ 439
Cdd:TIGR02168  405 LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL-DAAERE 483


                   ....*..
gi 300793996   440 VAERQFQ 446
Cdd:TIGR02168  484 LAQLQAR 490
PTZ00121 PTZ00121
MAEBL; Provisional
 112-477 5.96e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 5.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  112 ERRLREQHRDLKSAR--EEQRKLMAEQLLYEHWRKNNPKLREIELDLHKKHVINSWATQKEEKKQQEATEKQE-NKQFEN 188
Cdd:PTZ00121 1114 ARKAEEAKKKAEDARkaEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEvRKAEEL 1193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  189 EYAAARQEAEARLKAEEERKQLEGQLQGEALR----QQMEELKQKEMEATKLKKEQENLLKQHWELERLDDERKQMAIVr 264
Cdd:PTZ00121 1194 RKAEDARKAEAARKAEEERKAEEARKAEDAKKaeavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAI- 1272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  265 rKTELGRILRHQYNAQLNRRTQQIQEELEAdgRILQALLEKDNELQQVELARR--EQAMADAAQMKQVIEEQLQLEKARE 342
Cdd:PTZ00121 1273 -KAEEARKADELKKAEEKKKADEAKKAEEK--KKADEAKKKAEEAKKADEAKKkaEEAKKKADAAKKKAEEAKKAAEAAK 1349

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  343 AElQQLLREEAKEMWEKREAEWAREQSARDKlmSEVLTGRQQQIQEKIEQNRRAQE-----ETLKYREELIKSLEEGKQL 417
Cdd:PTZ00121 1350 AE-AEAAADEAEAAEEKAEAAEKKKEEAKKK--ADAAKKKAEEKKKADEAKKKAEEdkkkaDELKKAAAAKKKADEAKKK 1426

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 300793996  418 A---LRAKEESEELKSARKQELEAQVAERQFQEWEAARQEEEEEKEAKKAEQLSNARLQQEAR 477
Cdd:PTZ00121 1427 AeekKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAK 1489
PRK12704 PRK12704
phosphodiesterase; Provisional
 226-371 5.98e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 5.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 226 LKQKEMEATKLKKEQENLLKQHWELERLDDERKqmaIVRRKTELgrilrhqynAQLNRRTQQIQEELEadgRILQALLEK 305
Cdd:PRK12704  44 LEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKE---LRERRNEL---------QKLEKRLLQKEENLD---RKLELLEKR 108

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 300793996 306 DNELQQVElARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMWEKREAEWAREQSAR 371
Cdd:PRK12704 109 EEELEKKE-KELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAKEILLEKVEEEARHEAAV 173
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 72-482 8.31e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 8.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  72 EEERRKNLEVRRERLRKLMLEEQDLLAEELEELRLSMSLRERRLREQHRDLKSAREEQRKLMAEQLLYEHWRKNNPKLRE 151
Cdd:COG1196  335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 152 IELDLHKKHVINSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQGEALRQQMEELKQKEM 231
Cdd:COG1196  415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 232 EATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADGR-------------- 297
Cdd:COG1196  495 LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaieylkaakagra 574

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 298 -ILQALLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMWEKREAEWAREQSARDKLMS 376
Cdd:COG1196  575 tFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 377 EVLTGRQQQIQEKIEQN-----------RRAQEETLKYREELIKSLEEGKQLALRAKEESEELKSARKQELEAQVAERQF 445
Cdd:COG1196  655 GGSAGGSLTGGSRRELLaalleaeaeleELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 300793996 446 QEWEAARQEEEEEKEAKKAEQLSNARLQQEARTMVKR 482
Cdd:COG1196  735 EELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
GyrA COG0188
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
231-295 5.60e-03

DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];


Pssm-ID: 439958 [Multi-domain]  Cd Length: 804  Bit Score: 39.25  E-value: 5.60e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 300793996 231 MEATKLKKEQENLLKQHWELER-LDDERKQMAIVrrKTELGRIlRHQYNAQlnRRTQQIQEELEAD 295
Cdd:COG0188  436 LEREKIEDEYAELLKEIAELEDiLASEERLLKII--KEELLEI-KKKYGDE--RRTEIEEAEGEID 496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 169-363 6.12e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 6.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 169 KEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQgeALRQQMEELKQKEMEA-TKLKKEQENLLKQH 247
Cdd:COG4942   33 QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA--ALEAELAELEKEIAELrAELEAQKEELAELL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996 248 WELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADgrilQALLEKDNELQQVELARREQAMADAAQM 327
Cdd:COG4942  111 RALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD----LAELAALRAELEAERAELEALLAELEEE 186

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 300793996 328 KQVIEEQLQLEKAREAELQQLLREEAKEMWEKREAE 363
Cdd:COG4942  187 RAALEALKAERQKLLARLEKELAELAAELAELQQEA 222
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 70-346 6.39e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 39.34  E-value: 6.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   70 KMEEER---RKNLEVRRERLRKLMLEEQDLLAEELEELRLSMSLRERRLREQHRDLKSAREEQRKLMAEQLLYEHWRKNN 146
Cdd:pfam17380 295 KMEQERlrqEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEI 374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  147 PKLREIELDLHKKHVINSWATQK-----------EEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQ 215
Cdd:pfam17380 375 SRMRELERLQMERQQKNERVRQEleaarkvkileEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLE 454

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996  216 GEALRQQMEELKQKEME--ATKLKKEQENLLKQHWELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEE-- 291
Cdd:pfam17380 455 EQERQQQVERLRQQEEErkRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEer 534

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 300793996  292 ---LEADGRILQALLEKDNELQQVELARREQAMADAAQMKQVIEEQLQLEKAREAELQ 346
Cdd:pfam17380 535 rreAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 82-475 6.80e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 39.18  E-value: 6.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996    82 RRERLRKLMLEEQDLLAEELEELRLSMSLRERRLREQHRDLKSAREEQRKLMAEQLLYEHWRKNNPKLREIELDLHKKHV 161
Cdd:pfam02463  629 LKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQRE 708

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   162 INSWATQKEEKKQQEATEKQENKQFENEYAAARQEAEARLKAEEERKQLEGQLQGEALRQQMEELKQKEMEATKLKKEQE 241
Cdd:pfam02463  709 KEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV 788

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   242 NLLKQHWELERLDDERKQMAIVRRKTELGRILRHQYNAQLNRRTQQIQEELEADGRILQALLEKDNELQQVELARREQAM 321
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300793996   322 ADAAQMKQVIEEQLQLEKAREAELQQLLREEAKEMWEKREAEWAREQSARDKLMSEVLTGRQQQIQEKIEQNRRAQEETL 401
Cdd:pfam02463  869 LQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEK 948

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 300793996   402 KYREELIKSLEEGKQLALRAKEESEELKSARKQELEAQVAERQFQEWEAARQEEEEEKEAKKAEQLSNARLQQE 475
Cdd:pfam02463  949 EKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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