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Conserved domains on  [gi|299522750|ref|NP_001177374|]
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Fanconi anemia core complex-associated protein 20 isoform a [Mus musculus]

Protein Classification

FANCA_interact and UBZ_FAAP20 domain-containing protein( domain architecture ID 12174456)

FANCA_interact and UBZ_FAAP20 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FANCA_interact pfam15751
FAAP20 FANCA interaction domain; This domain is found at the N-terminus of Fanconi ...
 34-145 7.16e-40

FAAP20 FANCA interaction domain; This domain is found at the N-terminus of Fanconi anemia-associated protein of 20 kDa (FAAP20), where it is responsible for interaction with Fanconi anemia group A protein (FANCA).


:

Pssm-ID: 464845  Cd Length: 108  Bit Score: 131.44  E-value: 7.16e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299522750   34 SKSEPWAALLRSTvsgTADWTPNrQPLPPLPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGSSRHLFCEP 113
Cdd:pfam15751   1 ESARLWAELLRTV---SADLTLD-GELPPLPAFPGQEPRRSPERTAPPEVFTVGSKTFSWTPFPPAPGGSGRSYRLLRGT 76

                          90       100       110
                  ....*....|....*....|....*....|..
gi 299522750  114 EGSLGSPTPSLKGCPALNSGRTPSAQECVPVQ 145
Cdd:pfam15751  77 GGPLGSPTRSPQGCPAPDPRGTPSAEEQPSVE 108
UBZ_FAAP20 super family cl24348
Ubiquitin-binding zinc-finger; This domain is the ubiquitin-binding zinc-finger of the Fanconi ...
 150-184 3.55e-15

Ubiquitin-binding zinc-finger; This domain is the ubiquitin-binding zinc-finger of the Fanconi anaemia-associated protein of 20 kDa.


The actual alignment was detected with superfamily member pfam15750:

Pssm-ID: 464844  Cd Length: 35  Bit Score: 65.96  E-value: 3.55e-15
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 299522750  150 LLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDV 184
Cdd:pfam15750   1 LQSCPMCQKEFPPGLSQLDIDGHLAQCLSESTDDV 35
 
Name Accession Description Interval E-value
FANCA_interact pfam15751
FAAP20 FANCA interaction domain; This domain is found at the N-terminus of Fanconi ...
 34-145 7.16e-40

FAAP20 FANCA interaction domain; This domain is found at the N-terminus of Fanconi anemia-associated protein of 20 kDa (FAAP20), where it is responsible for interaction with Fanconi anemia group A protein (FANCA).


Pssm-ID: 464845  Cd Length: 108  Bit Score: 131.44  E-value: 7.16e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299522750   34 SKSEPWAALLRSTvsgTADWTPNrQPLPPLPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGSSRHLFCEP 113
Cdd:pfam15751   1 ESARLWAELLRTV---SADLTLD-GELPPLPAFPGQEPRRSPERTAPPEVFTVGSKTFSWTPFPPAPGGSGRSYRLLRGT 76

                          90       100       110
                  ....*....|....*....|....*....|..
gi 299522750  114 EGSLGSPTPSLKGCPALNSGRTPSAQECVPVQ 145
Cdd:pfam15751  77 GGPLGSPTRSPQGCPAPDPRGTPSAEEQPSVE 108
UBZ_FAAP20 pfam15750
Ubiquitin-binding zinc-finger; This domain is the ubiquitin-binding zinc-finger of the Fanconi ...
 150-184 3.55e-15

Ubiquitin-binding zinc-finger; This domain is the ubiquitin-binding zinc-finger of the Fanconi anaemia-associated protein of 20 kDa.


Pssm-ID: 464844  Cd Length: 35  Bit Score: 65.96  E-value: 3.55e-15
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 299522750  150 LLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDV 184
Cdd:pfam15750   1 LQSCPMCQKEFPPGLSQLDIDGHLAQCLSESTDDV 35
 
Name Accession Description Interval E-value
FANCA_interact pfam15751
FAAP20 FANCA interaction domain; This domain is found at the N-terminus of Fanconi ...
 34-145 7.16e-40

FAAP20 FANCA interaction domain; This domain is found at the N-terminus of Fanconi anemia-associated protein of 20 kDa (FAAP20), where it is responsible for interaction with Fanconi anemia group A protein (FANCA).


Pssm-ID: 464845  Cd Length: 108  Bit Score: 131.44  E-value: 7.16e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299522750   34 SKSEPWAALLRSTvsgTADWTPNrQPLPPLPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGSSRHLFCEP 113
Cdd:pfam15751   1 ESARLWAELLRTV---SADLTLD-GELPPLPAFPGQEPRRSPERTAPPEVFTVGSKTFSWTPFPPAPGGSGRSYRLLRGT 76

                          90       100       110
                  ....*....|....*....|....*....|..
gi 299522750  114 EGSLGSPTPSLKGCPALNSGRTPSAQECVPVQ 145
Cdd:pfam15751  77 GGPLGSPTRSPQGCPAPDPRGTPSAEEQPSVE 108
UBZ_FAAP20 pfam15750
Ubiquitin-binding zinc-finger; This domain is the ubiquitin-binding zinc-finger of the Fanconi ...
 150-184 3.55e-15

Ubiquitin-binding zinc-finger; This domain is the ubiquitin-binding zinc-finger of the Fanconi anaemia-associated protein of 20 kDa.


Pssm-ID: 464844  Cd Length: 35  Bit Score: 65.96  E-value: 3.55e-15
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 299522750  150 LLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDV 184
Cdd:pfam15750   1 LQSCPMCQKEFPPGLSQLDIDGHLAQCLSESTDDV 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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