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Conserved domains on  [gi|281360365|ref|NP_001163082|]
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lingerer, isoform F [Drosophila melanogaster]

Protein Classification

DEAD/DEAH box helicase; LCP family protein( domain architecture ID 13485270)

DEAD/DEAH box-containing ATP-dependent helicase catalyzes the unwinding of DNA or RNA| LytR-CpsA-Psr (LCP) family protein is implicated in the attachment of anionic polymers to cell wall peptidoglycan in bacteria

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UBA_UBP2_like cd14277
UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins; The family contains ...
 85-122 1.93e-12

UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins; The family contains some uncharacterized ubiquitin-associated proteins, including UBAP-2 and its homolog, UBAP2-like [UBP2L, also called protein NICE-4 (for newly identified cDNA from the epidermal differentiation complex EDC)], both of which contain an N-terminal ubiquitin-associated (UBA) domain along with a highly conserved, but function unknown domain (DUF3697).


:

Pssm-ID: 270463  Cd Length: 38  Bit Score: 62.58  E-value: 1.93e-12
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 281360365   85 INEKVLLLLTMTQRSEEEVCCALNECDYDLEAAANFLI 122
Cdd:cd14277     1 IQEKVKQVMELTGRSEDEAVVALHDCDNDVNRAINFLL 38
DUF3697 pfam12478
Ubiquitin-associated protein 2; This domain family is found in eukaryotes, and is ...
 575-607 1.24e-11

Ubiquitin-associated protein 2; This domain family is found in eukaryotes, and is approximately 30 amino acids in length. The family is found in association with pfam00627. There are two conserved sequence motifs: AVEMPG and QFG.


:

Pssm-ID: 372135 [Multi-domain]  Cd Length: 32  Bit Score: 60.14  E-value: 1.24e-11
                           10        20        30
                   ....*....|....*....|....*....|...
gi 281360365   575 PPSKIPASAVEMPGDnALNNIGYLDVQFGALDF 607
Cdd:pfam12478    1 PPSKIPASAVEMPGD-SLNSISSLDVQFGALDF 32
PRK12678 super family cl36163
transcription termination factor Rho; Provisional
 16-229 5.74e-06

transcription termination factor Rho; Provisional


The actual alignment was detected with superfamily member PRK12678:

Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 50.67  E-value: 5.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360365   16 ARNQKKSNASNSGGGGTGHHDGVSHAAAAGKKGGQDASKTDKPEKAQPKATTEQLRIAQITNSTTEDPQINEKVlllltm 95
Cdd:PRK12678   58 ARGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERR------ 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360365   96 tQRSEEEVccalnecdydleaaanflieelpQGAFAKYEKKRKNKAANNTADGAAGDGDWADGNGNADRREKSRNRSSNR 175
Cdd:PRK12678  132 -ERGEAAR-----------------------RGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAER 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 281360365  176 GGTRGSSDSRGWRGRETRENERNQRESREPWSGQNAGQDRGDDRANDNYRGQRN 229
Cdd:PRK12678  188 GERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGD 241
 
Name Accession Description Interval E-value
UBA_UBP2_like cd14277
UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins; The family contains ...
 85-122 1.93e-12

UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins; The family contains some uncharacterized ubiquitin-associated proteins, including UBAP-2 and its homolog, UBAP2-like [UBP2L, also called protein NICE-4 (for newly identified cDNA from the epidermal differentiation complex EDC)], both of which contain an N-terminal ubiquitin-associated (UBA) domain along with a highly conserved, but function unknown domain (DUF3697).


Pssm-ID: 270463  Cd Length: 38  Bit Score: 62.58  E-value: 1.93e-12
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 281360365   85 INEKVLLLLTMTQRSEEEVCCALNECDYDLEAAANFLI 122
Cdd:cd14277     1 IQEKVKQVMELTGRSEDEAVVALHDCDNDVNRAINFLL 38
DUF3697 pfam12478
Ubiquitin-associated protein 2; This domain family is found in eukaryotes, and is ...
 575-607 1.24e-11

Ubiquitin-associated protein 2; This domain family is found in eukaryotes, and is approximately 30 amino acids in length. The family is found in association with pfam00627. There are two conserved sequence motifs: AVEMPG and QFG.


Pssm-ID: 372135 [Multi-domain]  Cd Length: 32  Bit Score: 60.14  E-value: 1.24e-11
                           10        20        30
                   ....*....|....*....|....*....|...
gi 281360365   575 PPSKIPASAVEMPGDnALNNIGYLDVQFGALDF 607
Cdd:pfam12478    1 PPSKIPASAVEMPGD-SLNSISSLDVQFGALDF 32
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 16-229 5.74e-06

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 50.67  E-value: 5.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360365   16 ARNQKKSNASNSGGGGTGHHDGVSHAAAAGKKGGQDASKTDKPEKAQPKATTEQLRIAQITNSTTEDPQINEKVlllltm 95
Cdd:PRK12678   58 ARGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERR------ 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360365   96 tQRSEEEVccalnecdydleaaanflieelpQGAFAKYEKKRKNKAANNTADGAAGDGDWADGNGNADRREKSRNRSSNR 175
Cdd:PRK12678  132 -ERGEAAR-----------------------RGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAER 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 281360365  176 GGTRGSSDSRGWRGRETRENERNQRESREPWSGQNAGQDRGDDRANDNYRGQRN 229
Cdd:PRK12678  188 GERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGD 241
 
Name Accession Description Interval E-value
UBA_UBP2_like cd14277
UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins; The family contains ...
 85-122 1.93e-12

UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins; The family contains some uncharacterized ubiquitin-associated proteins, including UBAP-2 and its homolog, UBAP2-like [UBP2L, also called protein NICE-4 (for newly identified cDNA from the epidermal differentiation complex EDC)], both of which contain an N-terminal ubiquitin-associated (UBA) domain along with a highly conserved, but function unknown domain (DUF3697).


Pssm-ID: 270463  Cd Length: 38  Bit Score: 62.58  E-value: 1.93e-12
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 281360365   85 INEKVLLLLTMTQRSEEEVCCALNECDYDLEAAANFLI 122
Cdd:cd14277     1 IQEKVKQVMELTGRSEDEAVVALHDCDNDVNRAINFLL 38
DUF3697 pfam12478
Ubiquitin-associated protein 2; This domain family is found in eukaryotes, and is ...
 575-607 1.24e-11

Ubiquitin-associated protein 2; This domain family is found in eukaryotes, and is approximately 30 amino acids in length. The family is found in association with pfam00627. There are two conserved sequence motifs: AVEMPG and QFG.


Pssm-ID: 372135 [Multi-domain]  Cd Length: 32  Bit Score: 60.14  E-value: 1.24e-11
                           10        20        30
                   ....*....|....*....|....*....|...
gi 281360365   575 PPSKIPASAVEMPGDnALNNIGYLDVQFGALDF 607
Cdd:pfam12478    1 PPSKIPASAVEMPGD-SLNSISSLDVQFGALDF 32
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 16-229 5.74e-06

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 50.67  E-value: 5.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360365   16 ARNQKKSNASNSGGGGTGHHDGVSHAAAAGKKGGQDASKTDKPEKAQPKATTEQLRIAQITNSTTEDPQINEKVlllltm 95
Cdd:PRK12678   58 ARGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERR------ 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360365   96 tQRSEEEVccalnecdydleaaanflieelpQGAFAKYEKKRKNKAANNTADGAAGDGDWADGNGNADRREKSRNRSSNR 175
Cdd:PRK12678  132 -ERGEAAR-----------------------RGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAER 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 281360365  176 GGTRGSSDSRGWRGRETRENERNQRESREPWSGQNAGQDRGDDRANDNYRGQRN 229
Cdd:PRK12678  188 GERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARGD 241
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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