NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|251823704|ref|NP_001156547|]
View 

protein IL-40 precursor [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Ig_C17orf99 pfam17736
C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein ...
 27-121 4.07e-46

C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein C17orf99, which is found across mammalian species.


:

Pssm-ID: 465476  Cd Length: 95  Bit Score: 149.57  E-value: 4.07e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823704   27 PVVSIAYKVLEVFPKGRWVLITCCAPQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFCWASSTS 106
Cdd:pfam17736   1 PVSQIAYKVLEVFPSGRRVLISCHASQGSPPITYSLVGSDGIVVAKKIPLHGEPANFSLNITLKSSPDLLTYQCQAANTS 80

                          90
                  ....*....|....*
gi 251823704  107 GAHVDSARLQMHWEL 121
Cdd:pfam17736  81 GTQVSSLRLQPPWEL 95
Ig_C17orf99 super family cl39263
C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein ...
 125-214 3.66e-37

C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein C17orf99, which is found across mammalian species.


The actual alignment was detected with superfamily member pfam17736:

Pssm-ID: 465476  Cd Length: 95  Bit Score: 126.46  E-value: 3.66e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823704  125 PVSELrANFTLQDRGAGPRVEMICQASSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSD----WFWCQAANN 200
Cdd:pfam17736   1 PVSQI-AYKVLEVFPSGRRVLISCHASQGSPPITYSLVGSDGIVVAKKIPLHGEPANFSLNITLKSSpdllTYQCQAANT 79

                          90
                  ....*....|....
gi 251823704  201 ANVQHSALTVVPPG 214
Cdd:pfam17736  80 SGTQVSSLRLQPPW 93
 
Name Accession Description Interval E-value
Ig_C17orf99 pfam17736
C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein ...
 27-121 4.07e-46

C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein C17orf99, which is found across mammalian species.


Pssm-ID: 465476  Cd Length: 95  Bit Score: 149.57  E-value: 4.07e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823704   27 PVVSIAYKVLEVFPKGRWVLITCCAPQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFCWASSTS 106
Cdd:pfam17736   1 PVSQIAYKVLEVFPSGRRVLISCHASQGSPPITYSLVGSDGIVVAKKIPLHGEPANFSLNITLKSSPDLLTYQCQAANTS 80

                          90
                  ....*....|....*
gi 251823704  107 GAHVDSARLQMHWEL 121
Cdd:pfam17736  81 GTQVSSLRLQPPWEL 95
Ig_C17orf99 pfam17736
C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein ...
 125-214 3.66e-37

C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein C17orf99, which is found across mammalian species.


Pssm-ID: 465476  Cd Length: 95  Bit Score: 126.46  E-value: 3.66e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823704  125 PVSELrANFTLQDRGAGPRVEMICQASSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSD----WFWCQAANN 200
Cdd:pfam17736   1 PVSQI-AYKVLEVFPSGRRVLISCHASQGSPPITYSLVGSDGIVVAKKIPLHGEPANFSLNITLKSSpdllTYQCQAANT 79

                          90
                  ....*....|....
gi 251823704  201 ANVQHSALTVVPPG 214
Cdd:pfam17736  80 SGTQVSSLRLQPPW 93
 
Name Accession Description Interval E-value
Ig_C17orf99 pfam17736
C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein ...
 27-121 4.07e-46

C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein C17orf99, which is found across mammalian species.


Pssm-ID: 465476  Cd Length: 95  Bit Score: 149.57  E-value: 4.07e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823704   27 PVVSIAYKVLEVFPKGRWVLITCCAPQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFCWASSTS 106
Cdd:pfam17736   1 PVSQIAYKVLEVFPSGRRVLISCHASQGSPPITYSLVGSDGIVVAKKIPLHGEPANFSLNITLKSSPDLLTYQCQAANTS 80

                          90
                  ....*....|....*
gi 251823704  107 GAHVDSARLQMHWEL 121
Cdd:pfam17736  81 GTQVSSLRLQPPWEL 95
Ig_C17orf99 pfam17736
C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein ...
 125-214 3.66e-37

C17orf99 Ig domain; This Ig domain is found in tandem in the uncharacterized human protein C17orf99, which is found across mammalian species.


Pssm-ID: 465476  Cd Length: 95  Bit Score: 126.46  E-value: 3.66e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823704  125 PVSELrANFTLQDRGAGPRVEMICQASSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSD----WFWCQAANN 200
Cdd:pfam17736   1 PVSQI-AYKVLEVFPSGRRVLISCHASQGSPPITYSLVGSDGIVVAKKIPLHGEPANFSLNITLKSSpdllTYQCQAANT 79

                          90
                  ....*....|....
gi 251823704  201 ANVQHSALTVVPPG 214
Cdd:pfam17736  80 SGTQVSSLRLQPPW 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH